Receptor
PDB id Resolution Class Description Source Keywords
4ORM 2.07 Å EC: 1.3.5.2 CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM DIHYDROOROTATE DEHYDROGENASE BOUND WITH INHIBITOR DSM338 (N-[3,5-DIFLUORO-( TRIFLUOROMETHYL)PHENYL]-5-METHYL-2-(TRIFLUOROMETHYL)[1,2, 4] TRIAZOLO[1,5-A]PYRIMIDIN-7-AMINE) PLASMODIUM FALCIPARUM ALPHA/BETA BARREL OXIDOREDUCTASE FMN MITOCHONDRIAL MEMBRAOXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
Ref.: FLUORINE MODULATES SPECIES SELECTIVITY IN THE TRIAZOLOPYRIMIDINE CLASS OF PLASMODIUM FALCIPARUM DIHYDROOROTATE DEHYDROGENASE INHIBITORS. J.MED.CHEM. V. 57 5381 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ORO A:1003;
Valid;
none;
submit data
156.096 C5 H4 N2 O4 C1=C(...
GOL A:1004;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
SO4 A:1005;
A:1006;
Invalid;
Invalid;
none;
none;
submit data
96.063 O4 S [O-]S...
2V6 A:1001;
Valid;
none;
ic50 = 0.0018 uM
397.226 C14 H7 F8 N5 Cc1cc...
FMN A:1002;
Valid;
none;
submit data
456.344 C17 H21 N4 O9 P Cc1cc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4ORM 2.07 Å EC: 1.3.5.2 CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM DIHYDROOROTATE DEHYDROGENASE BOUND WITH INHIBITOR DSM338 (N-[3,5-DIFLUORO-( TRIFLUOROMETHYL)PHENYL]-5-METHYL-2-(TRIFLUOROMETHYL)[1,2, 4] TRIAZOLO[1,5-A]PYRIMIDIN-7-AMINE) PLASMODIUM FALCIPARUM ALPHA/BETA BARREL OXIDOREDUCTASE FMN MITOCHONDRIAL MEMBRAOXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
Ref.: FLUORINE MODULATES SPECIES SELECTIVITY IN THE TRIAZOLOPYRIMIDINE CLASS OF PLASMODIUM FALCIPARUM DIHYDROOROTATE DEHYDROGENASE INHIBITORS. J.MED.CHEM. V. 57 5381 2014
Members (10)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 3I65 ic50 = 0.047 uM JZ8 C16 H15 N5 Cc1cc([n+]....
2 4RX0 - D65 C14 H12 F7 N5 S Cc1cc(n2c(....
3 5DEL ic50 = 16 nM D59 C14 H10 Cl2 N2 O3 Cc1c(cccc1....
4 5TBO - 78Z C14 H11 F5 N6 Cc1cc(n2c(....
5 4CQ8 ic50 = 0.08 uM JBW C17 H14 N4 O S Cc1nc2c(cc....
6 3I68 ic50 = 0.056 uM J4Z C20 H15 N5 Cc1cc(n2c(....
7 4ORM ic50 = 0.0018 uM 2V6 C14 H7 F8 N5 Cc1cc(n2c(....
8 3O8A ic50 = 0.022 uM O8A C17 H14 F3 N3 O2 S Cc1nc2cc(c....
9 5FI8 ic50 = 0.0046 uM 5Y5 C18 H18 Br F2 N5 Cc1cc(n2c(....
10 3I6R ic50 = 0.28 uM J5Z C13 H10 F3 N5 Cc1cc(n2c(....
70% Homology Family (11)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1TV5 Ki ~ 1000 nM A26 C12 H9 F3 N2 O2 C/C(=C(C#N....
2 3I65 ic50 = 0.047 uM JZ8 C16 H15 N5 Cc1cc([n+]....
3 4RX0 - D65 C14 H12 F7 N5 S Cc1cc(n2c(....
4 5DEL ic50 = 16 nM D59 C14 H10 Cl2 N2 O3 Cc1c(cccc1....
5 5TBO - 78Z C14 H11 F5 N6 Cc1cc(n2c(....
6 4CQ8 ic50 = 0.08 uM JBW C17 H14 N4 O S Cc1nc2c(cc....
7 3I68 ic50 = 0.056 uM J4Z C20 H15 N5 Cc1cc(n2c(....
8 4ORM ic50 = 0.0018 uM 2V6 C14 H7 F8 N5 Cc1cc(n2c(....
9 3O8A ic50 = 0.022 uM O8A C17 H14 F3 N3 O2 S Cc1nc2cc(c....
10 5FI8 ic50 = 0.0046 uM 5Y5 C18 H18 Br F2 N5 Cc1cc(n2c(....
11 3I6R ic50 = 0.28 uM J5Z C13 H10 F3 N5 Cc1cc(n2c(....
50% Homology Family (44)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1TV5 Ki ~ 1000 nM A26 C12 H9 F3 N2 O2 C/C(=C(C#N....
2 3I65 ic50 = 0.047 uM JZ8 C16 H15 N5 Cc1cc([n+]....
3 4RX0 - D65 C14 H12 F7 N5 S Cc1cc(n2c(....
4 5DEL ic50 = 16 nM D59 C14 H10 Cl2 N2 O3 Cc1c(cccc1....
5 5TBO - 78Z C14 H11 F5 N6 Cc1cc(n2c(....
6 4CQ8 ic50 = 0.08 uM JBW C17 H14 N4 O S Cc1nc2c(cc....
7 3I68 ic50 = 0.056 uM J4Z C20 H15 N5 Cc1cc(n2c(....
8 4ORM ic50 = 0.0018 uM 2V6 C14 H7 F8 N5 Cc1cc(n2c(....
9 3O8A ic50 = 0.022 uM O8A C17 H14 F3 N3 O2 S Cc1nc2cc(c....
10 5FI8 ic50 = 0.0046 uM 5Y5 C18 H18 Br F2 N5 Cc1cc(n2c(....
11 3I6R ic50 = 0.28 uM J5Z C13 H10 F3 N5 Cc1cc(n2c(....
12 3KVL ic50 = 5.5 uM 7Z5 C17 H19 N3 O3 CCC(=O)Nc1....
13 3F1Q ic50 = 0.117 uM BCE C17 H14 N2 O2 C/C(=C(C#N....
14 2FPT ic50 = 33 nM ILB C20 H14 F5 N O4 c1cc(cc(c1....
15 3G0X ic50 = 0.053 uM MD7 C19 H16 N2 O2 c1ccc(cc1)....
16 2PRL ic50 = 81 nM R2C C20 H17 N O4 COc1ccc(c(....
17 3FJ6 ic50 = 0.022 uM CIH C17 H12 Cl2 N2 O2 C/C(=C(C#N....
18 4OQV ic50 = 1.6 uM 2V6 C14 H7 F8 N5 Cc1cc(n2c(....
19 2B0M - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
20 5MVC ic50 = 0.016 uM Y9B C15 H7 F4 N3 O2 S c1ccc(cc1)....
21 3U2O ic50 = 110 nM 03U C20 H17 F N2 O4 CC/C(=C(C#....
22 3KVM ic50 = 0.5 uM 951 C18 H13 Cl N2 O3 c1ccc(c(c1....
23 1D3H - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
24 2FQI ic50 = 7 nM ILH C20 H10 F7 N O4 c1cc(cc(c1....
25 3ZWS ic50 = 0.051 uM AVQ C13 H10 Cl2 N4 O S Cc1cc(n2c(....
26 5K9D - FNR C17 H23 N4 O9 P Cc1cc2c(cc....
27 5MVD ic50 = 0.041 uM U91 C18 H13 F4 N3 O2 Cc1c(c(nn1....
28 2FPY ic50 = 2 nM ILF C19 H10 F5 N O4 S c1cc(cc(c1....
29 5K9C ic50 = 0.56 uM MLJ C21 H21 F3 N2 O3 c1ccc2c(c1....
30 3G0U ic50 = 0.2 uM MDY C18 H15 Cl N2 O3 C/C(=C(C#N....
31 4IGH ic50 = 1 nM 1EA C26 H22 F N O3 Cc1cc(c(cc....
32 3FJL ic50 = 0.13 uM CJH C19 H18 N2 O3 CCOc1cccc(....
33 2PRH ic50 = 15 nM 238 C23 H15 Cl F N O2 Cc1c(c2cc(....
34 2FPV ic50 = 44 nM ILC C19 H14 F N O4 S COc1cccc(c....
35 3ZWT ic50 = 0.013 uM KFZ C14 H12 Cl2 N4 O S CCc1cc(n2c....
36 3KVK ic50 = 0.7 uM 6X1 C14 H10 Cl2 N2 O3 c1ccc(c(c1....
37 1D3G - BRE C23 H16 F N O2 Cc1c(c2cc(....
38 2BXV ic50 = 280 nM 3FT C20 H15 F4 N O4 c1cc(cc(c1....
39 3KVJ ic50 = 0.1 uM 1X5 C18 H19 N3 O3 CN(Cc1cccn....
40 5MUT ic50 = 0.045 uM HYT C16 H10 F4 N4 O2 Cn1nc(c(n1....
41 2WV8 ic50 = 0.21 uM VGN C21 H17 N O3 CC(=O)Nc1c....
42 1UUO ic50 = 6 nM BRF C23 H15 F2 N O2 Cc1c(c2cc(....
43 4ORI ic50 = 0.088 uM 2V6 C14 H7 F8 N5 Cc1cc(n2c(....
44 1UUM ic50 = 698 nM AFI C22 H19 Cl O3 c1ccc2c(c1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ORO; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 ORO 1 1
Ligand no: 2; Ligand: 2V6; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 2V6 1 1
2 78Z 0.492958 0.941176
3 D65 0.478873 0.813559
Ligand no: 3; Ligand: FMN; Similar ligands found: 16
No: Ligand ECFP6 Tc MDL keys Tc
1 FMN 1 1
2 RBF 0.75641 0.876712
3 RS3 0.571429 0.831169
4 FAS 0.543307 0.876543
5 FAD 0.543307 0.876543
6 FAE 0.539062 0.865854
7 DAL FAD PER 0.5 0.833333
8 LFN 0.475 0.643836
9 C3F 0.473684 0.74359
10 CF4 0.463918 0.734177
11 FAY 0.446043 0.864198
12 FNR 0.444444 0.909091
13 RFL 0.442857 0.845238
14 4LS 0.411215 0.875
15 1VY 0.406593 0.769231
16 DLZ 0.404494 0.782051
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4ORM; Ligand: ORO; Similar sites found: 279
This union binding pocket(no: 1) in the query (biounit: 4orm.bio1) has 61 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4I67 G G G RPC 0.01496 0.44412 None
2 5N8V KZZ 0.0417 0.42319 None
3 1YRX FMN 0.046 0.4108 None
4 1VYP TNF 0.000293 0.4898 1.37363
5 1VYP FMN 0.0003589 0.48223 1.37363
6 1K7L 544 0.009074 0.42015 1.38889
7 3SP6 IL2 0.002034 0.46929 1.40351
8 2NPA MMB 0.002852 0.45496 1.48148
9 2HHP FLC 0.003067 0.45069 1.49626
10 3UDZ ADP 0.04021 0.40531 1.49626
11 3FEI CTM 0.01326 0.41786 1.49813
12 4M5P FMN 0.0002962 0.50151 1.74564
13 3VV1 GAL FUC 0.04356 0.41755 1.875
14 2PX6 DH9 0.02601 0.4207 1.89873
15 2GOU FMN 0.003522 0.42075 1.91781
16 3WMX THR 0.004094 0.44351 1.95531
17 5W3Y ACO 0.0114 0.46182 1.98864
18 1DJN FMN 0.004705 0.4385 1.99501
19 1ZC9 PMP 0.03723 0.40698 1.99501
20 1RJD SAM 0.03922 0.40585 2.09581
21 3IPQ 965 0.01389 0.40298 2.12014
22 4JIQ 1L5 0.000265 0.48805 2.12202
23 4JIQ FMN 0.000265 0.48805 2.12202
24 3TDC 0EU 0.0006007 0.52873 2.24439
25 5VLQ ANP 0.04032 0.4146 2.24439
26 2PIA FMN 0.02777 0.41058 2.24439
27 2FLI DX5 0.004874 0.44394 2.27273
28 2VVG ADP 0.04536 0.42874 2.28571
29 2Q3O FMN 0.0001496 0.51116 2.30179
30 3GLC R5P 0.02406 0.42914 2.37288
31 3ATY FMN 0.0005837 0.47635 2.37467
32 2AKO ADP 0.03704 0.41275 2.39044
33 5EYW PGA 0.01291 0.45183 2.40964
34 3W54 RNB 0.02524 0.4183 2.43161
35 5K13 6Q7 0.03403 0.40372 2.43902
36 2DBX GLU 0.04379 0.4274 2.45902
37 4M26 AKG 0.01854 0.44958 2.47253
38 2HSA FMN 0.00006822 0.50255 2.49377
39 3A2Q ACA ACA 0.01022 0.43811 2.49377
40 2R40 20E 0.02297 0.40448 2.63158
41 5K53 STE 0.01082 0.43048 2.67176
42 3CHT 4NB 0.04857 0.42398 2.67857
43 2QCD U5P 0.02381 0.41384 2.69231
44 1Z48 FMN 0.00008891 0.54674 2.74314
45 1Z42 FMN 0.0001659 0.54428 2.74314
46 1Z44 FMN 0.0001286 0.5442 2.74314
47 1Z41 FMN 0.0001 0.54413 2.74314
48 2UZ1 TPP 0.01252 0.41394 2.74314
49 5VRH OLB 0.01379 0.45728 2.87356
50 4WQ2 3SU 0.04598 0.40505 2.89017
51 1P4C FMN 0.002952 0.42853 2.89474
52 3O01 DXC 0.03806 0.44115 2.92208
53 5LX9 OLB 0.00378 0.46776 2.9316
54 5DG2 GAL GLC 0.01699 0.40439 2.96296
55 1OX5 1PR 0.005024 0.42629 2.99252
56 2G50 ALA 0.04434 0.41813 2.99252
57 5KOR GDP 0.02572 0.41221 2.99252
58 1E4I NFG 0.0484 0.40698 2.99252
59 4WOH 4NP 0.03082 0.42236 3.01205
60 3WV6 GAL BGC 0.03177 0.40965 3.04054
61 2WG9 OCA 0.03559 0.43101 3.07692
62 3VGL ANP 0.01387 0.43477 3.11526
63 3IL6 B83 0.01397 0.42509 3.11526
64 1TPY 16A 0.02137 0.42511 3.13589
65 5V3Y 5V8 0.003245 0.4803 3.14685
66 1QPR PPC 0.02948 0.40672 3.16901
67 1QDS PGA 0.01039 0.45276 3.18725
68 3KRU FMN 0.001005 0.445 3.207
69 4RYV ZEA 0.01696 0.44112 3.22581
70 2O1V ADP 0.005558 0.46758 3.2419
71 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 0.002343 0.50179 3.34728
72 5UGW GSH 0.01798 0.47665 3.42857
73 3ET1 ET1 0.009309 0.44014 3.43643
74 4I9A NCN 0.008642 0.44176 3.47222
75 4UP4 NDG 0.02613 0.43674 3.49127
76 4UP4 NAG 0.02613 0.43674 3.49127
77 3SQP 3J8 0.04313 0.42834 3.49127
78 1OYB FMN 0.0007233 0.47568 3.5
79 1OYB HBA 0.001237 0.45537 3.5
80 3M31 FAD 0.01856 0.41113 3.60825
81 2JGV ADP 0.04472 0.41459 3.63636
82 5CHR 4NC 0.007663 0.47077 3.64964
83 1RBL CAP 0.01434 0.41892 3.66972
84 3G58 988 0.03936 0.421 3.67454
85 5HGZ ACO 0.01568 0.412 3.7037
86 4NES UDP 0.03338 0.41214 3.74332
87 3TAO PGH 0.01135 0.45066 3.74532
88 5W3X ACO 0.0425 0.42761 3.75
89 3V49 PK0 0.02699 0.40129 3.7594
90 3ZGJ RMN 0.02493 0.43581 3.77358
91 3B6C SDN 0.008479 0.4668 3.84615
92 4Y24 TD2 0.02929 0.42809 3.8961
93 2BTM PGA 0.01565 0.44716 3.96825
94 1ICP FMN 0.0001575 0.48723 3.98936
95 4IA6 EIC 0.00003123 0.61636 3.99003
96 3NV6 CAM 0.008908 0.43822 3.99003
97 1WDD CAP 0.01575 0.42257 3.99003
98 4NAE 1GP 0.001151 0.52128 4
99 2Q3R FMN 0.00001273 0.57165 4.03226
100 2GTE VA 0.006988 0.43063 4.03226
101 4QNW FMN 0.00006534 0.53255 4.08163
102 1NQ7 ARL 0.02901 0.40965 4.09836
103 2Q4V ACO 0.02086 0.40406 4.11765
104 3VKC FPQ 0.007824 0.43419 4.1958
105 4XP7 FNR 0.0002014 0.51857 4.2394
106 4TMC FMN 0.00035 0.494 4.2394
107 4TMC HBA 0.0009655 0.46653 4.2394
108 2C6Q IMP 0.009786 0.42126 4.2394
109 4V3I ASP LEU THR ARG PRO 0.0147 0.4575 4.28016
110 2V68 CAP 0.01772 0.42009 4.28571
111 2V63 CAP 0.01559 0.41994 4.28571
112 2V67 CAP 0.01613 0.41924 4.28571
113 2VDH CAP 0.01717 0.41794 4.28571
114 1IR2 CAP 0.01815 0.41679 4.28571
115 3A75 GLU 0.03273 0.43482 4.32432
116 2BYC FMN 0.0103 0.44504 4.37956
117 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 0.003508 0.5074 4.42177
118 2WPX ACO 0.02291 0.41748 4.42478
119 1TIQ COA 0.01836 0.43188 4.44444
120 2FDW D3G 0.01123 0.45522 4.48878
121 3FAL LO2 0.01123 0.40472 4.54545
122 4UA3 COA 0.006183 0.44223 4.63918
123 3GAY P6T 0.01356 0.42573 4.64396
124 4BI7 PGA 0.01555 0.44732 4.66926
125 1M2Z BOG 0.02233 0.44296 4.66926
126 5NBW 8SK 0.01214 0.44506 4.6729
127 2CIX CEJ 0.04589 0.40944 4.68227
128 1DKF BMS 0.01097 0.42436 4.72103
129 4A3R CIT 0.0209 0.42892 4.73815
130 5M45 AMP 0.03463 0.41426 4.7619
131 4M8E 29V 0.02206 0.41016 4.7619
132 4POJ 2VP 0.0257 0.4046 4.7619
133 2YPI PGA 0.02695 0.43009 4.8583
134 5XDT ZI7 0.01667 0.4061 4.87013
135 1UZH CAP 0.01775 0.41725 4.91803
136 5OCS FMN 0.0001861 0.52025 4.98753
137 1Q23 FUA 0.03876 0.40349 5.02283
138 1B57 PGH 0.009653 0.45451 5.02793
139 2YFB SIN 0.01395 0.43667 5.03876
140 2R14 FMN 0.001189 0.45612 5.03979
141 2R14 TXD 0.002053 0.43499 5.03979
142 1WS1 BB2 0.03642 0.41313 5.12821
143 3B0P FMN 0.0000212 0.57849 5.14286
144 1SW0 PGA 0.01199 0.44536 5.24194
145 1LYX PGA 0.0179 0.43246 5.24194
146 3IX9 MTX 0.03064 0.41404 5.26316
147 3AQT RCO 0.03189 0.43653 5.30612
148 5UC9 MYR 0.0159 0.45408 5.30973
149 4RC8 STE 0.01426 0.41904 5.40541
150 2Z6J FMN 0.0008369 0.45665 5.42169
151 4OAR 2S0 0.02205 0.41546 5.42636
152 5KZV HCD 0.01703 0.44511 5.51181
153 5DKK FMN 0.02594 0.41203 5.51724
154 1Q6O LG6 0.00764 0.44804 5.55556
155 1TRD PGH 0.004281 0.46922 5.6
156 4MLM TLA 0.0312 0.43201 5.61225
157 3AIH BMA MAN MAN 0.01705 0.4507 5.64516
158 2D6M LBT 0.02336 0.42383 5.66038
159 4DR9 BB2 0.02616 0.42057 5.72917
160 2ZFI ADP 0.03236 0.42571 5.7377
161 1SQS TLA 0.04309 0.42503 5.78512
162 1G27 BB1 0.01643 0.42773 5.95238
163 4YMZ 13P 0.011 0.45573 5.9761
164 4V2O CLQ 0.03374 0.4284 6.09756
165 4UTU LRY 0.002797 0.47458 6.11354
166 4UTW RFW 0.002374 0.47398 6.11354
167 5V4R MGT 0.02287 0.4534 6.17284
168 2FJK 13P 0.0354 0.42355 6.22951
169 3QCP FAD 0.02329 0.40192 6.23441
170 5A5W GUO 0.005886 0.40015 6.32411
171 3B9Z CO2 0.001774 0.48928 6.48379
172 1IR1 CAP 0.0321 0.4075 6.50407
173 1UJP CIT 0.01983 0.4236 6.64207
174 2HFP NSI 0.02351 0.40639 6.73759
175 3BW2 FMN 0.0001274 0.48769 6.77507
176 5MBC FMN 0.03259 0.41564 6.79887
177 2OL1 UMP 0.04485 0.40842 6.80272
178 1Q1Y BB2 0.04946 0.40912 6.80628
179 3KO0 TFP 0.0137 0.44864 6.93069
180 3RET SAL 0.03988 0.4141 6.93069
181 3RET PYR 0.03988 0.4141 6.93069
182 3SXN COA 0.03487 0.40321 6.98254
183 5TWO 7MV 0.0191 0.4185 6.98529
184 5HCV 60R 0.03002 0.40147 7.00389
185 4NB5 2JT 0.03466 0.40853 7.01754
186 3R5W F42 0.04067 0.40506 7.14286
187 1OFD AKG 0.0005256 0.4536 7.23192
188 1OFD FMN 0.000675 0.44412 7.23192
189 3EXS 5RP 0.001065 0.50661 7.23982
190 3OGN 3OG 0.04209 0.40702 7.25806
191 4JEJ 1GP 0.0002403 0.53573 7.37705
192 5HZ9 5M8 0.04259 0.40675 7.40741
193 2RDT FMN 0.0004342 0.47857 7.49354
194 2RDT 2RD 0.000651 0.4554 7.49354
195 2BJ4 OHT 0.02288 0.41469 7.53968
196 1GVF PGH 0.009362 0.46434 7.69231
197 1KBJ FMN 0.0004396 0.47834 7.73067
198 3N9R TD3 0.03204 0.42594 7.81759
199 3C56 PH4 0.01504 0.42354 7.81759
200 2TPS TPS 0.0104 0.41753 7.92952
201 2PRG BRL 0.02123 0.42211 7.95455
202 4EKQ NPO 0.0327 0.4126 8.02139
203 3IT6 ORN 0.04264 0.42626 8.0402
204 3LLI FAD 0.01979 0.40283 8.04598
205 2IYG FMN 0.02964 0.42426 8.06452
206 1WW5 SGA BGC 0.0245 0.44035 8.125
207 2Z6I FMN 0.0005618 0.48445 8.13253
208 3P9T TCL 0.02885 0.42845 8.21918
209 1T0S BML 0.03395 0.41515 8.22943
210 1NU4 MLA 0.04394 0.4224 8.24742
211 3OVR 5SP 0.008232 0.43019 8.33333
212 2YLD CMO 0.03301 0.43341 8.66142
213 4Q9N 0WE 0.01372 0.43851 8.72483
214 2CNT COA 0.03998 0.40283 8.75
215 2GJN FMN 0.0004796 0.47667 8.84146
216 2GJN NIS 0.0005858 0.46628 8.84146
217 4IXH IMP 0.01096 0.42166 8.86427
218 1ZFJ IMP 0.0327 0.40712 8.97756
219 1S8G DAO 0.04943 0.41223 9.09091
220 5EY0 GTP 0.02218 0.43473 9.48905
221 2ZRU FMN 0.0003432 0.45284 9.51087
222 5EPQ OLA 0.01474 0.4334 9.7561
223 4OKZ 3E9 0.004172 0.44089 9.86301
224 3CR3 ADP 0.02472 0.41305 9.91736
225 5TCI MLI 0.001254 0.51804 10.1449
226 5XNA SHV 0.01435 0.45685 10.1449
227 1AL8 FMN 0.0003843 0.48823 10.585
228 1AL8 DHP 0.0005859 0.46018 10.585
229 5LWY OLB 0.02998 0.42066 10.6164
230 2VWA PTY 0.01782 0.45396 10.8911
231 3SIX GDP 0.04568 0.41409 10.9091
232 3D78 NBB 0.02146 0.41071 10.9244
233 3L0E G58 0.004367 0.43152 11.0672
234 3KFC 61X 0.01247 0.40493 11.0672
235 4MG8 27J 0.04053 0.41372 11.3725
236 1NF8 BOG 0.003274 0.4992 11.5942
237 4XPL ACO 0.01003 0.43851 11.6564
238 4HBM 0Y7 0.01305 0.43612 11.6667
239 4Z4P SAH 0.04958 0.40615 12.0482
240 3W9Z FMN 0.0005332 0.49783 12.1118
241 1VHN FMN 0.00247 0.48193 12.2642
242 5KAU RHQ 0.04133 0.40471 12.7273
243 4LWU 20U 0.01349 0.4389 12.9412
244 5LGA 6VH 0.007599 0.40542 12.9676
245 1SDW IYT 0.0336 0.42133 13.0573
246 4IBF 1D5 0.02511 0.42473 13.1783
247 4WT2 3UD 0.01258 0.40916 13.3333
248 3CTL S6P 0.04085 0.40237 13.4199
249 4AF0 IMP 0.004811 0.44107 13.7157
250 3QH2 3NM 0.0005228 0.53574 14.0271
251 4XB4 45D 0.03053 0.40351 14.4737
252 4OAS 2SW 0.009091 0.44787 14.5833
253 2YMZ LAT 0.01873 0.4043 14.6154
254 2WOR 2AN 0.002705 0.49967 15
255 1A78 TDG 0.04749 0.40556 15.6716
256 1L6O SER LEU LYS LEU MET THR THR VAL 0.04695 0.40738 15.7895
257 1VKF CIT 0.01659 0.45007 15.9574
258 1MT1 AG2 0.03391 0.43698 17.3077
259 1C3X 8IG 0.03291 0.42708 18.4211
260 2F6U CIT 0.005395 0.47801 19.6581
261 2NLI FMN 0.0005019 0.48293 19.837
262 2NLI LAC 0.00124 0.45234 19.837
263 1KBI PYR 0.0002317 0.48702 21.4464
264 5EYK 5U5 0.02389 0.40143 22.0339
265 1UZD CAP 0.0186 0.41629 23.1343
266 5CSS G3P 0.01937 0.44197 23.4513
267 1RV1 IMZ 0.02107 0.43224 24.7059
268 4EWN 0VR 0.001621 0.48244 28.4585
269 1GTE FMN 0.0000000001783 0.70435 30.6733
270 1GTE IUR 0.0000000001783 0.70435 30.6733
271 4WZH FMN 0.000000000005629 0.82713 31.1239
272 3MJY FMN 0.000000000001032 0.80734 36.9942
273 3MJY IJZ 0.000000000001032 0.80734 36.9942
274 1EP2 FMN 0.0000000001395 0.74983 39.2283
275 1EP2 ORO 0.00000000002116 0.74061 39.2283
276 3OIX FMN 0.00000000001076 0.83326 39.4203
277 3C3N FMN 0.0000000000005467 0.79531 44.5513
278 1OVD ORO 0.0000000000001664 0.80769 47.91
279 1OVD FMN 0.0000000000001664 0.80769 47.91
Pocket No.: 2; Query (leader) PDB : 4ORM; Ligand: FMN; Similar sites found: 247
This union binding pocket(no: 2) in the query (biounit: 4orm.bio1) has 61 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4I67 G G G RPC 0.01496 0.44412 None
2 5N8V KZZ 0.0417 0.42319 None
3 1YRX FMN 0.02357 0.42291 None
4 1VYP TNF 0.000293 0.4898 1.37363
5 1VYP FMN 0.0003589 0.48223 1.37363
6 1K7L 544 0.009074 0.42015 1.38889
7 3SP6 IL2 0.002034 0.46929 1.40351
8 2NPA MMB 0.002852 0.45496 1.48148
9 2HHP FLC 0.003067 0.45069 1.49626
10 3UDZ ADP 0.04021 0.40531 1.49626
11 3FEI CTM 0.01326 0.41786 1.49813
12 3VV1 GAL FUC 0.04356 0.41755 1.875
13 2PX6 DH9 0.02601 0.4207 1.89873
14 2GOU FMN 0.003522 0.42075 1.91781
15 3WMX THR 0.004094 0.44351 1.95531
16 5W3Y ACO 0.0114 0.46182 1.98864
17 1DJN FMN 0.004705 0.4385 1.99501
18 1ZC9 PMP 0.03723 0.40698 1.99501
19 1RJD SAM 0.03922 0.40585 2.09581
20 4JIQ 1L5 0.000265 0.48805 2.12202
21 4JIQ FMN 0.000265 0.48805 2.12202
22 3TDC 0EU 0.0006007 0.52873 2.24439
23 5VLQ ANP 0.04032 0.4146 2.24439
24 2PIA FMN 0.02777 0.41058 2.24439
25 2FLI DX5 0.004874 0.44394 2.27273
26 2VVG ADP 0.04536 0.42874 2.28571
27 2Q3O FMN 0.0001496 0.51116 2.30179
28 3GLC R5P 0.02406 0.42914 2.37288
29 3ATY FMN 0.0005837 0.47635 2.37467
30 2AKO ADP 0.03704 0.41275 2.39044
31 5EYW PGA 0.01291 0.45183 2.40964
32 3W54 RNB 0.02524 0.4183 2.43161
33 5K13 6Q7 0.03403 0.40372 2.43902
34 2DBX GLU 0.04379 0.4274 2.45902
35 4M26 AKG 0.01854 0.44958 2.47253
36 2HSA FMN 0.00006822 0.50255 2.49377
37 2OEM 1AE 0.04174 0.41622 2.49377
38 2R40 20E 0.02297 0.40448 2.63158
39 5K53 STE 0.01082 0.43048 2.67176
40 3CHT 4NB 0.04857 0.42398 2.67857
41 2QCD U5P 0.02381 0.41384 2.69231
42 1Z42 FMN 0.0001659 0.54428 2.74314
43 1Z44 FMN 0.0001286 0.5442 2.74314
44 1Z41 FMN 0.0001 0.54413 2.74314
45 2UZ1 TPP 0.01252 0.41394 2.74314
46 5VRH OLB 0.01379 0.45728 2.87356
47 4WQ2 3SU 0.04598 0.40505 2.89017
48 3O01 DXC 0.03806 0.44115 2.92208
49 5LX9 OLB 0.00378 0.46776 2.9316
50 5DG2 GAL GLC 0.01699 0.40439 2.96296
51 1OX5 1PR 0.005024 0.42629 2.99252
52 2G50 ALA 0.04434 0.41813 2.99252
53 5KOR GDP 0.02572 0.41221 2.99252
54 4WOH 4NP 0.03082 0.42236 3.01205
55 3WV6 GAL BGC 0.03177 0.40965 3.04054
56 2WG9 OCA 0.03559 0.43101 3.07692
57 1TPY 16A 0.02137 0.42511 3.13589
58 5V3Y 5V8 0.003245 0.4803 3.14685
59 1QPR PPC 0.02948 0.40672 3.16901
60 3KRU FMN 0.001005 0.445 3.207
61 4RYV ZEA 0.01696 0.44112 3.22581
62 2O1V ADP 0.005558 0.46758 3.2419
63 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 0.002343 0.50179 3.34728
64 4NTO 1PW 0.02544 0.43522 3.38164
65 5UGW GSH 0.01798 0.47665 3.42857
66 3ET1 ET1 0.009309 0.44014 3.43643
67 4UP4 NDG 0.02613 0.43674 3.49127
68 4UP4 NAG 0.02613 0.43674 3.49127
69 3SQP 3J8 0.04313 0.42834 3.49127
70 3M31 FAD 0.01856 0.41113 3.60825
71 2JGV ADP 0.04472 0.41459 3.63636
72 5CHR 4NC 0.007663 0.47077 3.64964
73 1RBL CAP 0.01434 0.41892 3.66972
74 3G58 988 0.03936 0.421 3.67454
75 5HGZ ACO 0.01568 0.412 3.7037
76 3TAO PGH 0.01135 0.45066 3.74532
77 5W3X ACO 0.0425 0.42761 3.75
78 3V49 PK0 0.02699 0.40129 3.7594
79 3ZGJ RMN 0.02493 0.43581 3.77358
80 3B6C SDN 0.008479 0.4668 3.84615
81 4Y24 TD2 0.02929 0.42809 3.8961
82 2BTM PGA 0.01565 0.44716 3.96825
83 1ICP FMN 0.0001575 0.48723 3.98936
84 4IA6 EIC 0.00003123 0.61636 3.99003
85 3NV6 CAM 0.008908 0.43822 3.99003
86 1WDD CAP 0.01575 0.42257 3.99003
87 3ER9 3AT 0.03527 0.41385 3.99003
88 4NAE 1GP 0.001151 0.52128 4
89 2Q3R FMN 0.00001273 0.57165 4.03226
90 2GTE VA 0.006988 0.43063 4.03226
91 4QNW FMN 0.00006534 0.53255 4.08163
92 1NQ7 ARL 0.02901 0.40965 4.09836
93 2Q4V ACO 0.02086 0.40406 4.11765
94 3VKC FPQ 0.007824 0.43419 4.1958
95 4XP7 FNR 0.0002014 0.51857 4.2394
96 4TMC FMN 0.00035 0.494 4.2394
97 4TMC HBA 0.0009655 0.46653 4.2394
98 2C6Q IMP 0.009786 0.42126 4.2394
99 4V3I ASP LEU THR ARG PRO 0.0147 0.4575 4.28016
100 2V68 CAP 0.01772 0.42009 4.28571
101 2V63 CAP 0.01559 0.41994 4.28571
102 2V67 CAP 0.01613 0.41924 4.28571
103 2VDH CAP 0.01717 0.41794 4.28571
104 1IR2 CAP 0.01815 0.41679 4.28571
105 3A75 GLU 0.03273 0.43482 4.32432
106 2BYC FMN 0.0103 0.44504 4.37956
107 2WPX ACO 0.02291 0.41748 4.42478
108 1TIQ COA 0.01836 0.43188 4.44444
109 2FDW D3G 0.01123 0.45522 4.48878
110 3FAL LO2 0.01123 0.40472 4.54545
111 4UA3 COA 0.006183 0.44223 4.63918
112 3GAY P6T 0.01356 0.42573 4.64396
113 1M2Z BOG 0.02233 0.44296 4.66926
114 5NBW 8SK 0.01214 0.44506 4.6729
115 2CIX CEJ 0.04589 0.40944 4.68227
116 1DKF BMS 0.01097 0.42436 4.72103
117 5M45 AMP 0.03463 0.41426 4.7619
118 4M8E 29V 0.02206 0.41016 4.7619
119 4POJ 2VP 0.0257 0.4046 4.7619
120 2YPI PGA 0.02695 0.43009 4.8583
121 5XDT ZI7 0.01667 0.4061 4.87013
122 1UZH CAP 0.01775 0.41725 4.91803
123 5OCS FMN 0.0001861 0.52025 4.98753
124 1Q23 FUA 0.03876 0.40349 5.02283
125 1B57 PGH 0.009653 0.45451 5.02793
126 2YFB SIN 0.01395 0.43667 5.03876
127 1WS1 BB2 0.03642 0.41313 5.12821
128 3B0P FMN 0.0000212 0.57849 5.14286
129 1SW0 PGA 0.01199 0.44536 5.24194
130 3IX9 MTX 0.03064 0.41404 5.26316
131 3AQT RCO 0.03189 0.43653 5.30612
132 5UC9 MYR 0.0159 0.45408 5.30973
133 4RC8 STE 0.01426 0.41904 5.40541
134 2Z6J FMN 0.0008369 0.45665 5.42169
135 4OAR 2S0 0.02205 0.41546 5.42636
136 5KZV HCD 0.01703 0.44511 5.51181
137 5DKK FMN 0.02594 0.41203 5.51724
138 1Q6O LG6 0.00764 0.44804 5.55556
139 1TRD PGH 0.004281 0.46922 5.6
140 4MLM TLA 0.0312 0.43201 5.61225
141 3AIH BMA MAN MAN 0.01705 0.4507 5.64516
142 2D6M LBT 0.02336 0.42383 5.66038
143 4DR9 BB2 0.02616 0.42057 5.72917
144 3HF3 FMN 0.0001496 0.51555 5.73066
145 2ZFI ADP 0.03236 0.42571 5.7377
146 1SQS TLA 0.04309 0.42503 5.78512
147 1G27 BB1 0.01643 0.42773 5.95238
148 4YMZ 13P 0.011 0.45573 5.9761
149 4V2O CLQ 0.03374 0.4284 6.09756
150 4UTU LRY 0.002797 0.47458 6.11354
151 4UTW RFW 0.002374 0.47398 6.11354
152 5V4R MGT 0.02287 0.4534 6.17284
153 2FJK 13P 0.0354 0.42355 6.22951
154 3QCP FAD 0.02329 0.40192 6.23441
155 5A5W GUO 0.005886 0.40015 6.32411
156 4Q4K FMN 0.0001789 0.49559 6.44258
157 1UJP CIT 0.01983 0.4236 6.64207
158 2HFP NSI 0.02351 0.40639 6.73759
159 5MBC FMN 0.03259 0.41564 6.79887
160 2OL1 UMP 0.04485 0.40842 6.80272
161 1Q1Y BB2 0.04946 0.40912 6.80628
162 3KO0 TFP 0.0137 0.44864 6.93069
163 3RET PYR 0.03988 0.4141 6.93069
164 3RET SAL 0.03988 0.4141 6.93069
165 3SXN COA 0.03487 0.40321 6.98254
166 5TWO 7MV 0.0191 0.4185 6.98529
167 5HCV 60R 0.03002 0.40147 7.00389
168 4NB5 2JT 0.03466 0.40853 7.01754
169 3R5W F42 0.04067 0.40506 7.14286
170 1OFD AKG 0.0005256 0.4536 7.23192
171 1OFD FMN 0.000675 0.44412 7.23192
172 3EXS 5RP 0.001065 0.50661 7.23982
173 3OGN 3OG 0.04209 0.40702 7.25806
174 5HZ9 5M8 0.04259 0.40675 7.40741
175 2BJ4 OHT 0.02288 0.41469 7.53968
176 3N9R TD3 0.03204 0.42594 7.81759
177 3C56 PH4 0.01504 0.42354 7.81759
178 2TPS TPS 0.0104 0.41753 7.92952
179 2PRG BRL 0.02123 0.42211 7.95455
180 4EKQ NPO 0.0327 0.4126 8.02139
181 3IT6 ORN 0.04264 0.42626 8.0402
182 3LLI FAD 0.01979 0.40283 8.04598
183 1WW5 SGA BGC 0.0245 0.44035 8.125
184 2Z6I FMN 0.0005618 0.48445 8.13253
185 3P9T TCL 0.02885 0.42845 8.21918
186 1T0S BML 0.03395 0.41515 8.22943
187 1NU4 MLA 0.04394 0.4224 8.24742
188 3OVR 5SP 0.008232 0.43019 8.33333
189 4Q9N 0WE 0.01372 0.43851 8.72483
190 2CNT COA 0.03998 0.40283 8.75
191 2GJN FMN 0.0004796 0.47667 8.84146
192 2GJN NIS 0.0005858 0.46628 8.84146
193 4IXH IMP 0.01096 0.42166 8.86427
194 1S8G DAO 0.04943 0.41223 9.09091
195 3T7S SAM 0.0376 0.40676 9.32836
196 5EY0 GTP 0.02218 0.43473 9.48905
197 2ZRU FMN 0.0003432 0.45284 9.51087
198 5EPQ OLA 0.01474 0.4334 9.7561
199 1X0P FAD 0.02636 0.42361 9.79021
200 4OKZ 3E9 0.004172 0.44089 9.86301
201 3CR3 ADP 0.02472 0.41305 9.91736
202 5TCI MLI 0.001254 0.51804 10.1449
203 5XNA SHV 0.01435 0.45685 10.1449
204 5LWY OLB 0.02998 0.42066 10.6164
205 2VWA PTY 0.01782 0.45396 10.8911
206 3SIX GDP 0.04568 0.41409 10.9091
207 3D78 NBB 0.02146 0.41071 10.9244
208 3L0E G58 0.004367 0.43152 11.0672
209 3KFC 61X 0.01247 0.40493 11.0672
210 4MG8 27J 0.04053 0.41372 11.3725
211 4XPL ACO 0.01003 0.43851 11.6564
212 4HBM 0Y7 0.01305 0.43612 11.6667
213 4Z4P SAH 0.04958 0.40615 12.0482
214 3W9Z FMN 0.0005332 0.49783 12.1118
215 1VHN FMN 0.00247 0.48193 12.2642
216 5KAU RHQ 0.04133 0.40471 12.7273
217 4LWU 20U 0.01349 0.4389 12.9412
218 5LGA 6VH 0.007599 0.40542 12.9676
219 1SDW IYT 0.0336 0.42133 13.0573
220 4IBF 1D5 0.02511 0.42473 13.1783
221 4WT2 3UD 0.01258 0.40916 13.3333
222 3CTL S6P 0.04085 0.40237 13.4199
223 3QH2 3NM 0.0005228 0.53574 14.0271
224 4XB4 45D 0.03053 0.40351 14.4737
225 1TB3 FMN 0.0004466 0.46507 14.4886
226 4OAS 2SW 0.009091 0.44787 14.5833
227 2YMZ LAT 0.01873 0.4043 14.6154
228 1A78 TDG 0.04749 0.40556 15.6716
229 1L6O SER LEU LYS LEU MET THR THR VAL 0.04695 0.40738 15.7895
230 1VKF CIT 0.01659 0.45007 15.9574
231 1MT1 AG2 0.03391 0.43698 17.3077
232 1C3X 8IG 0.03291 0.42708 18.4211
233 2F6U CIT 0.005395 0.47801 19.6581
234 5EYK 5U5 0.02389 0.40143 22.0339
235 1UZD CAP 0.0186 0.41629 23.1343
236 5CSS G3P 0.01937 0.44197 23.4513
237 1RV1 IMZ 0.02107 0.43224 24.7059
238 4EWN 0VR 0.001621 0.48244 28.4585
239 1GTE IUR 0.0000000001783 0.70435 30.6733
240 1GTE FMN 0.0000000001783 0.70435 30.6733
241 4WZH FMN 0.000000000005629 0.82713 31.1239
242 3MJY FMN 0.000000000001032 0.80734 36.9942
243 3MJY IJZ 0.000000000001032 0.80734 36.9942
244 3OIX FMN 0.00000000001076 0.83326 39.4203
245 3C3N FMN 0.0000000000005467 0.79531 44.5513
246 1OVD FMN 0.0000000000001664 0.80769 47.91
247 1OVD ORO 0.0000000000001664 0.80769 47.91
Pocket No.: 3; Query (leader) PDB : 4ORM; Ligand: 2V6; Similar sites found: 247
This union binding pocket(no: 3) in the query (biounit: 4orm.bio1) has 61 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4I67 G G G RPC 0.01496 0.44412 None
2 5N8V KZZ 0.0417 0.42319 None
3 1YRX FMN 0.02357 0.42291 None
4 1VYP TNF 0.000293 0.4898 1.37363
5 1VYP FMN 0.0003589 0.48223 1.37363
6 1K7L 544 0.009074 0.42015 1.38889
7 3SP6 IL2 0.002034 0.46929 1.40351
8 2NPA MMB 0.002852 0.45496 1.48148
9 2HHP FLC 0.003067 0.45069 1.49626
10 3UDZ ADP 0.04021 0.40531 1.49626
11 3FEI CTM 0.01326 0.41786 1.49813
12 3VV1 GAL FUC 0.04356 0.41755 1.875
13 2PX6 DH9 0.02601 0.4207 1.89873
14 2GOU FMN 0.003522 0.42075 1.91781
15 3WMX THR 0.004094 0.44351 1.95531
16 5W3Y ACO 0.0114 0.46182 1.98864
17 1DJN FMN 0.004705 0.4385 1.99501
18 1ZC9 PMP 0.03723 0.40698 1.99501
19 1RJD SAM 0.03922 0.40585 2.09581
20 4JIQ 1L5 0.000265 0.48805 2.12202
21 4JIQ FMN 0.000265 0.48805 2.12202
22 3TDC 0EU 0.0006007 0.52873 2.24439
23 5VLQ ANP 0.04032 0.4146 2.24439
24 2PIA FMN 0.02777 0.41058 2.24439
25 2FLI DX5 0.004874 0.44394 2.27273
26 2VVG ADP 0.04536 0.42874 2.28571
27 2Q3O FMN 0.0001496 0.51116 2.30179
28 3GLC R5P 0.02406 0.42914 2.37288
29 3ATY FMN 0.0005837 0.47635 2.37467
30 2AKO ADP 0.03704 0.41275 2.39044
31 5EYW PGA 0.01291 0.45183 2.40964
32 3W54 RNB 0.02524 0.4183 2.43161
33 5K13 6Q7 0.03403 0.40372 2.43902
34 2DBX GLU 0.04379 0.4274 2.45902
35 4M26 AKG 0.01854 0.44958 2.47253
36 2HSA FMN 0.00006822 0.50255 2.49377
37 2OEM 1AE 0.04174 0.41622 2.49377
38 2R40 20E 0.02297 0.40448 2.63158
39 5K53 STE 0.01082 0.43048 2.67176
40 3CHT 4NB 0.04857 0.42398 2.67857
41 2QCD U5P 0.02381 0.41384 2.69231
42 1Z42 FMN 0.0001659 0.54428 2.74314
43 1Z44 FMN 0.0001286 0.5442 2.74314
44 1Z41 FMN 0.0001 0.54413 2.74314
45 2UZ1 TPP 0.01252 0.41394 2.74314
46 5VRH OLB 0.01379 0.45728 2.87356
47 4WQ2 3SU 0.04598 0.40505 2.89017
48 3O01 DXC 0.03806 0.44115 2.92208
49 5LX9 OLB 0.00378 0.46776 2.9316
50 5DG2 GAL GLC 0.01699 0.40439 2.96296
51 1OX5 1PR 0.005024 0.42629 2.99252
52 2G50 ALA 0.04434 0.41813 2.99252
53 5KOR GDP 0.02572 0.41221 2.99252
54 4WOH 4NP 0.03082 0.42236 3.01205
55 3WV6 GAL BGC 0.03177 0.40965 3.04054
56 2WG9 OCA 0.03559 0.43101 3.07692
57 1TPY 16A 0.02137 0.42511 3.13589
58 5V3Y 5V8 0.003245 0.4803 3.14685
59 1QPR PPC 0.02948 0.40672 3.16901
60 3KRU FMN 0.001005 0.445 3.207
61 4RYV ZEA 0.01696 0.44112 3.22581
62 2O1V ADP 0.005558 0.46758 3.2419
63 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 0.002343 0.50179 3.34728
64 4NTO 1PW 0.02544 0.43522 3.38164
65 5UGW GSH 0.01798 0.47665 3.42857
66 3ET1 ET1 0.009309 0.44014 3.43643
67 4UP4 NDG 0.02613 0.43674 3.49127
68 4UP4 NAG 0.02613 0.43674 3.49127
69 3SQP 3J8 0.04313 0.42834 3.49127
70 3M31 FAD 0.01856 0.41113 3.60825
71 2JGV ADP 0.04472 0.41459 3.63636
72 5CHR 4NC 0.007663 0.47077 3.64964
73 1RBL CAP 0.01434 0.41892 3.66972
74 3G58 988 0.03936 0.421 3.67454
75 5HGZ ACO 0.01568 0.412 3.7037
76 3TAO PGH 0.01135 0.45066 3.74532
77 5W3X ACO 0.0425 0.42761 3.75
78 3V49 PK0 0.02699 0.40129 3.7594
79 3ZGJ RMN 0.02493 0.43581 3.77358
80 3B6C SDN 0.008479 0.4668 3.84615
81 4Y24 TD2 0.02929 0.42809 3.8961
82 2BTM PGA 0.01565 0.44716 3.96825
83 1ICP FMN 0.0001575 0.48723 3.98936
84 4IA6 EIC 0.00003123 0.61636 3.99003
85 3NV6 CAM 0.008908 0.43822 3.99003
86 1WDD CAP 0.01575 0.42257 3.99003
87 3ER9 3AT 0.03527 0.41385 3.99003
88 4NAE 1GP 0.001151 0.52128 4
89 2Q3R FMN 0.00001273 0.57165 4.03226
90 2GTE VA 0.006988 0.43063 4.03226
91 4QNW FMN 0.00006534 0.53255 4.08163
92 1NQ7 ARL 0.02901 0.40965 4.09836
93 2Q4V ACO 0.02086 0.40406 4.11765
94 3VKC FPQ 0.007824 0.43419 4.1958
95 4XP7 FNR 0.0002014 0.51857 4.2394
96 4TMC FMN 0.00035 0.494 4.2394
97 4TMC HBA 0.0009655 0.46653 4.2394
98 2C6Q IMP 0.009786 0.42126 4.2394
99 4V3I ASP LEU THR ARG PRO 0.0147 0.4575 4.28016
100 2V68 CAP 0.01772 0.42009 4.28571
101 2V63 CAP 0.01559 0.41994 4.28571
102 2V67 CAP 0.01613 0.41924 4.28571
103 2VDH CAP 0.01717 0.41794 4.28571
104 1IR2 CAP 0.01815 0.41679 4.28571
105 3A75 GLU 0.03273 0.43482 4.32432
106 2BYC FMN 0.0103 0.44504 4.37956
107 2WPX ACO 0.02291 0.41748 4.42478
108 1TIQ COA 0.01836 0.43188 4.44444
109 2FDW D3G 0.01123 0.45522 4.48878
110 3FAL LO2 0.01123 0.40472 4.54545
111 4UA3 COA 0.006183 0.44223 4.63918
112 3GAY P6T 0.01356 0.42573 4.64396
113 1M2Z BOG 0.02233 0.44296 4.66926
114 5NBW 8SK 0.01214 0.44506 4.6729
115 2CIX CEJ 0.04589 0.40944 4.68227
116 1DKF BMS 0.01097 0.42436 4.72103
117 5M45 AMP 0.03463 0.41426 4.7619
118 4M8E 29V 0.02206 0.41016 4.7619
119 4POJ 2VP 0.0257 0.4046 4.7619
120 2YPI PGA 0.02695 0.43009 4.8583
121 5XDT ZI7 0.01667 0.4061 4.87013
122 1UZH CAP 0.01775 0.41725 4.91803
123 5OCS FMN 0.0001861 0.52025 4.98753
124 1Q23 FUA 0.03876 0.40349 5.02283
125 1B57 PGH 0.009653 0.45451 5.02793
126 2YFB SIN 0.01395 0.43667 5.03876
127 1WS1 BB2 0.03642 0.41313 5.12821
128 3B0P FMN 0.0000212 0.57849 5.14286
129 1SW0 PGA 0.01199 0.44536 5.24194
130 3IX9 MTX 0.03064 0.41404 5.26316
131 3AQT RCO 0.03189 0.43653 5.30612
132 5UC9 MYR 0.0159 0.45408 5.30973
133 4RC8 STE 0.01426 0.41904 5.40541
134 2Z6J FMN 0.0008369 0.45665 5.42169
135 4OAR 2S0 0.02205 0.41546 5.42636
136 5KZV HCD 0.01703 0.44511 5.51181
137 5DKK FMN 0.02594 0.41203 5.51724
138 1Q6O LG6 0.00764 0.44804 5.55556
139 1TRD PGH 0.004281 0.46922 5.6
140 4MLM TLA 0.0312 0.43201 5.61225
141 3AIH BMA MAN MAN 0.01705 0.4507 5.64516
142 2D6M LBT 0.02336 0.42383 5.66038
143 4DR9 BB2 0.02616 0.42057 5.72917
144 3HF3 FMN 0.0001496 0.51555 5.73066
145 2ZFI ADP 0.03236 0.42571 5.7377
146 1SQS TLA 0.04309 0.42503 5.78512
147 1G27 BB1 0.01643 0.42773 5.95238
148 4YMZ 13P 0.011 0.45573 5.9761
149 4V2O CLQ 0.03374 0.4284 6.09756
150 4UTU LRY 0.002797 0.47458 6.11354
151 4UTW RFW 0.002374 0.47398 6.11354
152 5V4R MGT 0.02287 0.4534 6.17284
153 2FJK 13P 0.0354 0.42355 6.22951
154 3QCP FAD 0.02329 0.40192 6.23441
155 5A5W GUO 0.005886 0.40015 6.32411
156 4Q4K FMN 0.0001789 0.49559 6.44258
157 1UJP CIT 0.01983 0.4236 6.64207
158 2HFP NSI 0.02351 0.40639 6.73759
159 5MBC FMN 0.03259 0.41564 6.79887
160 2OL1 UMP 0.04485 0.40842 6.80272
161 1Q1Y BB2 0.04946 0.40912 6.80628
162 3KO0 TFP 0.0137 0.44864 6.93069
163 3RET PYR 0.03988 0.4141 6.93069
164 3RET SAL 0.03988 0.4141 6.93069
165 3SXN COA 0.03487 0.40321 6.98254
166 5TWO 7MV 0.0191 0.4185 6.98529
167 5HCV 60R 0.03002 0.40147 7.00389
168 4NB5 2JT 0.03466 0.40853 7.01754
169 3R5W F42 0.04067 0.40506 7.14286
170 1OFD AKG 0.0005256 0.4536 7.23192
171 1OFD FMN 0.000675 0.44412 7.23192
172 3EXS 5RP 0.001065 0.50661 7.23982
173 3OGN 3OG 0.04209 0.40702 7.25806
174 5HZ9 5M8 0.04259 0.40675 7.40741
175 2BJ4 OHT 0.02288 0.41469 7.53968
176 3N9R TD3 0.03204 0.42594 7.81759
177 3C56 PH4 0.01504 0.42354 7.81759
178 2TPS TPS 0.0104 0.41753 7.92952
179 2PRG BRL 0.02123 0.42211 7.95455
180 4EKQ NPO 0.0327 0.4126 8.02139
181 3IT6 ORN 0.04264 0.42626 8.0402
182 3LLI FAD 0.01979 0.40283 8.04598
183 1WW5 SGA BGC 0.0245 0.44035 8.125
184 2Z6I FMN 0.0005618 0.48445 8.13253
185 3P9T TCL 0.02885 0.42845 8.21918
186 1T0S BML 0.03395 0.41515 8.22943
187 1NU4 MLA 0.04394 0.4224 8.24742
188 3OVR 5SP 0.008232 0.43019 8.33333
189 4Q9N 0WE 0.01372 0.43851 8.72483
190 2CNT COA 0.03998 0.40283 8.75
191 2GJN FMN 0.0004796 0.47667 8.84146
192 2GJN NIS 0.0005858 0.46628 8.84146
193 4IXH IMP 0.01096 0.42166 8.86427
194 1S8G DAO 0.04943 0.41223 9.09091
195 3T7S SAM 0.0376 0.40676 9.32836
196 5EY0 GTP 0.02218 0.43473 9.48905
197 2ZRU FMN 0.0003432 0.45284 9.51087
198 5EPQ OLA 0.01474 0.4334 9.7561
199 1X0P FAD 0.02636 0.42361 9.79021
200 4OKZ 3E9 0.004172 0.44089 9.86301
201 3CR3 ADP 0.02472 0.41305 9.91736
202 5TCI MLI 0.001254 0.51804 10.1449
203 5XNA SHV 0.01435 0.45685 10.1449
204 5LWY OLB 0.02998 0.42066 10.6164
205 2VWA PTY 0.01782 0.45396 10.8911
206 3SIX GDP 0.04568 0.41409 10.9091
207 3D78 NBB 0.02146 0.41071 10.9244
208 3L0E G58 0.004367 0.43152 11.0672
209 3KFC 61X 0.01247 0.40493 11.0672
210 4MG8 27J 0.04053 0.41372 11.3725
211 4XPL ACO 0.01003 0.43851 11.6564
212 4HBM 0Y7 0.01305 0.43612 11.6667
213 4Z4P SAH 0.04958 0.40615 12.0482
214 3W9Z FMN 0.0005332 0.49783 12.1118
215 1VHN FMN 0.00247 0.48193 12.2642
216 5KAU RHQ 0.04133 0.40471 12.7273
217 4LWU 20U 0.01349 0.4389 12.9412
218 5LGA 6VH 0.007599 0.40542 12.9676
219 1SDW IYT 0.0336 0.42133 13.0573
220 4IBF 1D5 0.02511 0.42473 13.1783
221 4WT2 3UD 0.01258 0.40916 13.3333
222 3CTL S6P 0.04085 0.40237 13.4199
223 3QH2 3NM 0.0005228 0.53574 14.0271
224 4XB4 45D 0.03053 0.40351 14.4737
225 1TB3 FMN 0.0004466 0.46507 14.4886
226 4OAS 2SW 0.009091 0.44787 14.5833
227 2YMZ LAT 0.01873 0.4043 14.6154
228 1A78 TDG 0.04749 0.40556 15.6716
229 1L6O SER LEU LYS LEU MET THR THR VAL 0.04695 0.40738 15.7895
230 1VKF CIT 0.01659 0.45007 15.9574
231 1MT1 AG2 0.03391 0.43698 17.3077
232 1C3X 8IG 0.03291 0.42708 18.4211
233 2F6U CIT 0.005395 0.47801 19.6581
234 5EYK 5U5 0.02389 0.40143 22.0339
235 1UZD CAP 0.0186 0.41629 23.1343
236 5CSS G3P 0.01937 0.44197 23.4513
237 1RV1 IMZ 0.02107 0.43224 24.7059
238 4EWN 0VR 0.001621 0.48244 28.4585
239 1GTE IUR 0.0000000001783 0.70435 30.6733
240 1GTE FMN 0.0000000001783 0.70435 30.6733
241 4WZH FMN 0.000000000005629 0.82713 31.1239
242 3MJY FMN 0.000000000001032 0.80734 36.9942
243 3MJY IJZ 0.000000000001032 0.80734 36.9942
244 3OIX FMN 0.00000000001076 0.83326 39.4203
245 3C3N FMN 0.0000000000005467 0.79531 44.5513
246 1OVD FMN 0.0000000000001664 0.80769 47.91
247 1OVD ORO 0.0000000000001664 0.80769 47.91
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