Receptor
PDB id Resolution Class Description Source Keywords
4P7U 1.5 Å NON-ENZYME: SIGNAL_HORMONE EXTRACELLULAR DOMAIN OF TYPE II TRANSFORMING GROWTH FACTOR B RECEPTOR IN COMPLEX WITH NDSB-201 HOMO SAPIENS NDSB-201 TYPE II TRANSFORMING GROWTH FACTOR BETA RECEPTOR PROTEIN
Ref.: THE NON-DETERGENT SULFOBETAINE-201 ACTS AS A PHARMA CHAPERONE TO PROMOTE FOLDING AND CRYSTALLIZATION OF II TGF-BETA RECEPTOR EXTRACELLULAR DOMAIN. PROTEIN EXPR.PURIF. V. 115 19 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
1PS A:201;
Valid;
Atoms found LESS than expected: % Diff = 0;
submit data
201.243 C8 H11 N O3 S c1cc[...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4P7U 1.5 Å NON-ENZYME: SIGNAL_HORMONE EXTRACELLULAR DOMAIN OF TYPE II TRANSFORMING GROWTH FACTOR B RECEPTOR IN COMPLEX WITH NDSB-201 HOMO SAPIENS NDSB-201 TYPE II TRANSFORMING GROWTH FACTOR BETA RECEPTOR PROTEIN
Ref.: THE NON-DETERGENT SULFOBETAINE-201 ACTS AS A PHARMA CHAPERONE TO PROMOTE FOLDING AND CRYSTALLIZATION OF II TGF-BETA RECEPTOR EXTRACELLULAR DOMAIN. PROTEIN EXPR.PURIF. V. 115 19 2015
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 286 families.
1 4P7U - 1PS C8 H11 N O3 S c1cc[n+](c....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 4P7U - 1PS C8 H11 N O3 S c1cc[n+](c....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 174 families.
1 4P7U - 1PS C8 H11 N O3 S c1cc[n+](c....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 1PS; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 1PS 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4P7U; Ligand: 1PS; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4p7u.bio1) has 9 residues
No: Leader PDB Ligand Sequence Similarity
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