Receptor
PDB id Resolution Class Description Source Keywords
4PC6 2.2 Å NON-ENZYME: OTHER ELONGATION FACTOR TU:TS COMPLEX WITH BOUND GDPNP ESCHERICHIA COLI G:GEF:NUCLEOTIDE COMPLEX ELONGATION FACTOR TRANSLATION PRSYNTHESIS
Ref.: STRUCTURAL OUTLINE OF THE DETAILED MECHANISM FOR EL FACTOR TS-MEDIATED GUANINE NUCLEOTIDE EXCHANGE ON E FACTOR TU. J.STRUCT.BIOL. V. 191 10 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL D:301;
C:301;
B:402;
D:302;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
GNP A:401;
B:401;
Valid;
Valid;
Atoms found MORE than expected: % Diff = 2;
none;
submit data
522.196 C10 H17 N6 O13 P3 c1nc2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4PC3 1.83 Å NON-ENZYME: OTHER ELONGATION FACTOR TU:TS COMPLEX WITH PARTIALLY BOUND GDP ESCHERICHIA COLI G:GEF:GDP COMPLEX ELONGATION FACTOR TRANSLATION PROTEIN S
Ref.: STRUCTURAL OUTLINE OF THE DETAILED MECHANISM FOR EL FACTOR TS-MEDIATED GUANINE NUCLEOTIDE EXCHANGE ON E FACTOR TU. J.STRUCT.BIOL. V. 191 10 2015
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 4PC6 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 4PC3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 4PC2 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 4PC6 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 4PC3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 4PC2 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 4PC6 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 4PC3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 4PC2 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GNP; Similar ligands found: 128
No: Ligand ECFP6 Tc MDL keys Tc
1 GNP 1 1
2 GDP 0.839506 0.973684
3 GP3 0.82716 0.948718
4 GTP 0.809524 0.973684
5 GNH 0.807229 0.986842
6 G1R 0.77907 0.961039
7 GCP 0.77907 0.948718
8 GSP 0.770115 0.925
9 5GP 0.756098 0.960526
10 G 0.756098 0.960526
11 G2R 0.747253 0.936709
12 GMV 0.747126 0.948718
13 GAV 0.714286 0.936709
14 GP2 0.712644 0.936709
15 G2P 0.711111 0.936709
16 Y9Z 0.708333 0.880952
17 GDP MG 0.696629 0.9
18 GDD 0.690722 0.936709
19 GDC 0.690722 0.936709
20 GKE 0.690722 0.936709
21 GDP BEF 0.688889 0.878049
22 G5P 0.686869 0.948718
23 GPG 0.684211 0.936709
24 GTG 0.683673 0.91358
25 GFB 0.683673 0.936709
26 GDR 0.683673 0.936709
27 JB2 0.68 0.936709
28 GKD 0.68 0.936709
29 G3A 0.676768 0.948718
30 6CK 0.676768 0.91358
31 GDX 0.673267 0.948718
32 ALF 5GP 0.67033 0.86747
33 GTP MG 0.666667 0.9
34 BEF GDP 0.666667 0.86747
35 YGP 0.663265 0.879518
36 GCP G 0.659574 0.911392
37 GPD 0.656863 0.902439
38 GDP AF3 0.645833 0.86747
39 GDP ALF 0.645833 0.86747
40 JB3 0.641509 0.925
41 DBG 0.640351 0.974359
42 G3D 0.638298 0.960526
43 G4P 0.625 0.960526
44 GMP 0.621951 0.857143
45 NGD 0.62037 0.936709
46 GGM 0.618182 0.925926
47 0O2 0.616162 0.960526
48 G G 0.61 0.911392
49 2MD 0.603604 0.870588
50 CAG 0.60177 0.904762
51 U2G 0.590909 0.91358
52 FEG 0.590909 0.858824
53 GDP 7MG 0.590476 0.888889
54 MGD 0.587719 0.870588
55 ZGP 0.585586 0.848837
56 CG2 0.580357 0.91358
57 ANP 0.568421 0.922078
58 PGD 0.567797 0.902439
59 MD1 0.567797 0.870588
60 3GP 0.56044 0.922078
61 TPG 0.558333 0.822222
62 GH3 0.55 0.948052
63 FE9 0.546219 0.778947
64 GPX 0.539216 0.922078
65 G4M 0.539062 0.860465
66 DGI 0.536082 0.9
67 BGO 0.535088 0.901235
68 IDP 0.53125 0.947368
69 DGT 0.53 0.9
70 2GP 0.526882 0.935065
71 G1R G1R 0.520325 0.901235
72 I2C FE2 CMO CMO 0.516667 0.811111
73 U A G G 0.512605 0.911392
74 AGO 0.504202 0.91358
75 G A A A 0.504202 0.9
76 P2G 0.5 0.860759
77 G1G 0.5 0.902439
78 MGP 0.49505 0.936709
79 PGD O 0.492063 0.831461
80 6G0 0.490196 0.936709
81 P1G 0.489796 0.85
82 DGP 0.474227 0.8875
83 DG 0.474227 0.8875
84 G G U 0.473684 0.911392
85 IMP 0.463918 0.934211
86 G2Q 0.462963 0.936709
87 GPC 0.459677 0.858824
88 G C 0.459016 0.878049
89 GTA 0.448276 0.91358
90 G7M 0.444444 0.924051
91 MAP 0.439252 0.898734
92 G G G RPC 0.435484 0.853659
93 B4P 0.434343 0.871795
94 AP5 0.434343 0.871795
95 ADP 0.434343 0.896104
96 A2D 0.43299 0.871795
97 U G A 0.431655 0.86747
98 G G G C 0.426357 0.890244
99 SGP 0.425743 0.807229
100 AU1 0.425743 0.922078
101 BA3 0.424242 0.871795
102 35G 0.423077 0.909091
103 PCG 0.423077 0.909091
104 A G C C 0.423077 0.888889
105 C2E 0.423077 0.897436
106 APC G U 0.421875 0.864198
107 ATP 0.421569 0.896104
108 ACQ 0.419048 0.873418
109 5GP 5GP 0.419048 0.860759
110 AQP 0.417476 0.896104
111 5FA 0.417476 0.896104
112 01G 0.417391 0.880952
113 UNP 0.415842 0.810127
114 AN2 0.415842 0.909091
115 6AD 0.415094 0.821429
116 ITT 0.411765 0.846154
117 M33 0.411765 0.860759
118 G C C C 0.410448 0.901235
119 G U34 0.408 0.86747
120 ACP 0.407767 0.873418
121 APR 0.403846 0.871795
122 AR6 0.403846 0.871795
123 DG DG 0.403509 0.845238
124 A4P 0.403226 0.848837
125 UCG 0.402985 0.888889
126 AD9 0.4 0.873418
127 SAP 0.4 0.851852
128 AGS 0.4 0.851852
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4PC3; Ligand: GDP; Similar sites found: 432
This union binding pocket(no: 1) in the query (biounit: 4pc3.bio1) has 19 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4REP FAD 0.03084 0.40153 1.52284
2 1V8K ANP 0.00009525 0.50425 1.77305
3 4ZNL BEF ADP 0.00004571 0.48318 1.82482
4 1XKV ATP 0.00009811 0.47768 2.12766
5 1NST A3P 0.001024 0.44254 2.12766
6 5MEX SZZ 0.01979 0.40808 2.17391
7 5MEX PAP 0.008985 0.40234 2.17391
8 3NHB ADP 0.00003626 0.44443 2.28426
9 3DEF GDP 0.000004177 0.54603 2.29008
10 5HCN GCP 0.00000002576 0.66342 2.29885
11 3BER AMP 0.003497 0.40218 2.40964
12 2J5V PCA 0.009657 0.41997 2.45232
13 3ZQ6 ADP ALF 0.0001219 0.49882 2.46914
14 2G77 GDP 0.000000001956 0.69743 2.48227
15 1YTM ATP 0.0002379 0.44199 2.48227
16 5BQ5 ADP BEF 0.0006354 0.45432 2.6455
17 3DZD ADP 0.004026 0.41388 2.83688
18 1YZQ GNP 0.00000001426 0.68084 2.94118
19 1ZUI SKM 0.001101 0.46615 2.97619
20 3Q72 GNP 0.000000001679 0.64004 3.01205
21 5I0H ADP BEF 0.0009767 0.44774 3.04569
22 2VVG ADP 0.0000004801 0.47435 3.19149
23 5TSH ANP 0.00007817 0.46424 3.19149
24 5TSH ADP 0.0001172 0.43141 3.19149
25 1P72 ADP 0.0006983 0.4715 3.29341
26 1QF5 GDP 0.01316 0.4534 3.29949
27 1QF5 RPL 0.01316 0.4534 3.29949
28 4PJ3 ANP 0.001738 0.43005 3.29949
29 2B8W ALF 5GP 0.002228 0.43706 3.35366
30 1JJV ATP 0.00004395 0.54105 3.39806
31 3FYH ADP 0.0013 0.44779 3.41615
32 5X40 ACP 0.001343 0.44535 3.42466
33 1T5C ADP 0.0000005808 0.47074 3.4384
34 2WKQ GTP 0.0000006191 0.59755 3.5461
35 2DPY ADP 0.00006187 0.52791 3.5461
36 1GOJ ADP 0.0000005423 0.47312 3.5461
37 2I4I AMP 0.006227 0.40009 3.5461
38 3TBK ANP 0.0003039 0.43681 3.5533
39 2Z5F A3P 0.009673 0.40272 3.69128
40 5UQW GDP 0.00000001194 0.67877 3.7037
41 1KMQ GNP 0.0000008662 0.5909 3.80435
42 1Z06 GNP 0.000000009259 0.68384 3.80711
43 1JJ7 ADP 0.000003591 0.61065 3.84615
44 1VKJ A3P 0.002595 0.42858 3.85965
45 5M04 GDP 0.000000000139 0.68043 3.88889
46 4PFO ADP 0.000672 0.46275 3.90071
47 4FCW ADP 0.0005296 0.44019 3.90071
48 3B7G ANP 0.0003592 0.44847 3.91304
49 1TX4 ALF GDP 0.000001082 0.51545 3.9548
50 1ION ADP 0.00008955 0.47971 4.11523
51 1VHT BA3 0.000672 0.44193 4.12844
52 4LPS GDP 0.00000003682 0.61417 4.13223
53 3BOS CDP 0.00005786 0.51456 4.13223
54 3Q85 GNP 0.0000000001785 0.69075 4.14201
55 2GDJ ANP 0.0002519 0.444 4.16667
56 1G3Q ADP 0.00002675 0.52338 4.21941
57 4AG5 ADP 0.00001126 0.5711 4.25532
58 5WRI A3P 0.0005511 0.46102 4.25532
59 2VF7 ADP 0.0004484 0.44078 4.25532
60 2XAU ADP 0.001201 0.4307 4.25532
61 5WRJ A3P 0.0005191 0.46609 4.29043
62 3RWO GDP 0.00000001848 0.6729 4.32432
63 5L3V GDP 0.0000006316 0.57216 4.34783
64 1OE0 TTP 0.00836 0.41372 4.34783
65 4PX9 ADP 0.0003401 0.43154 4.45205
66 2GCN GDP 0.0000002478 0.61289 4.47761
67 2GCO GNP 0.000000289 0.60074 4.47761
68 4U00 ADP 0.000007055 0.44045 4.5082
69 2F9L GDP 0.00000001473 0.58001 4.52261
70 3QBT GNP 0.00000003842 0.54342 4.5977
71 2BIF ANP 0.000587 0.47649 4.60993
72 2BIF SIN 0.0009936 0.47649 4.60993
73 1IHU AF3 0.00002593 0.46814 4.60993
74 1IHU ADP 0.0000255 0.45989 4.60993
75 3QF7 ANP 0.0008092 0.44931 4.65753
76 1Z08 GNP 0.00000003965 0.652 4.70588
77 1OIV GDP 0.00000001005 0.68509 4.71204
78 1OIX GDP 0.00000002494 0.66691 4.71204
79 1NY5 ADP 0.001477 0.43543 4.82234
80 4O33 TZN 0.03735 0.40165 4.82234
81 4O33 3PG 0.03735 0.40165 4.82234
82 1VG0 GDP 0.000000005142 0.67485 4.83092
83 1VG8 GNP 0.00000002571 0.66899 4.83092
84 2CHG ANP 0.0004316 0.45926 4.86726
85 3COB ADP 0.0000009849 0.48034 4.87805
86 2JAQ DCP 0.008934 0.40772 4.87805
87 1KY3 GDP 0.00000001482 0.6545 4.94506
88 2W58 ADP 0.00002621 0.42511 4.9505
89 2FAH GDP 0.00009881 0.4852 4.96454
90 4GOX A3P 0.000263 0.47766 4.96454
91 2AWN ADP 0.000002074 0.44017 4.96454
92 4Q1A UDP 0.002251 0.5063 5
93 4Q1A 2XZ 0.002251 0.5063 5
94 4LJ9 ACP 0.00066 0.46423 5.01475
95 2ZEJ GDP 0.00000002943 0.66627 5.07614
96 1W5T ANP 0.001968 0.434 5.07614
97 1W5T ADP 0.004503 0.41383 5.07614
98 4TTQ ATP 0.0001406 0.45833 5.11628
99 3KJI ADP 0.002704 0.45098 5.11811
100 1H65 GDP 0.00001196 0.48318 5.18518
101 3H86 AP5 0.0007777 0.47205 5.20833
102 1TU3 GNP 0.000000005378 0.69761 5.26316
103 5KUT GDP 0.00000002389 0.62195 5.29101
104 1R2Q GNP 0.00000001455 0.69722 5.29412
105 4R2I ANP 0.0009448 0.41691 5.31915
106 3BD9 A3P 0.001371 0.42252 5.35714
107 1F2U ATP 0.001981 0.44273 5.36913
108 4NON GDP 0.0000000503 0.65803 5.38462
109 2D7C GTP 0.00000001952 0.67181 5.38922
110 1VG1 GDP 0.0000000004824 0.68935 5.40541
111 1VG9 GDP 0.000000001555 0.66964 5.40541
112 1RYH GNP 0.00000006452 0.61465 5.41872
113 3CYI ATP 0.00178 0.45907 5.45455
114 2ZE7 DST 0.01446 0.40264 5.5336
115 1UJ2 C5P 0.01262 0.43215 5.55556
116 1UJ2 ADP 0.0169 0.42573 5.55556
117 1WF3 GNP 0.00000003107 0.66519 5.58376
118 1SVK ALF GDP 0.0000000776 0.65401 5.58376
119 5KDO GDP 0.00000004734 0.59067 5.58376
120 1GP2 GDP 0.0000000408 0.56857 5.58376
121 1Z0F GDP 0.0000000006455 0.73775 5.58659
122 3VX3 ADP 0.0004691 0.45993 5.64516
123 2XTZ GSP 0.00000006865 0.64664 5.67376
124 2Q2Y ADP 0.000719 0.47996 5.67376
125 2Q2Y MKR 0.0007148 0.47889 5.67376
126 1SVM ATP 0.002181 0.46371 5.67376
127 4A4Z ANP 0.002316 0.43826 5.67376
128 3FVQ ATP 0.001955 0.43413 5.67376
129 3DC4 ADP 0.00004358 0.45096 5.81395
130 2BEK ATP 0.005795 0.43389 5.83658
131 2IXE ATP 0.001156 0.44642 5.83756
132 5XCO GDP 0.000000006661 0.66987 5.84795
133 2BME GNP 0.00000004462 0.65527 5.91398
134 1MH1 GNP 0.0000004587 0.61105 5.91398
135 1G4U GDP 0.0000004687 0.56171 5.97826
136 1KAO GDP 0.00000002891 0.64529 5.98802
137 4MKG AP5 0.003343 0.44762 5.99078
138 4MKF AP5 0.003826 0.44583 5.99078
139 4D0N GDP 0.00000002284 0.60955 6.02837
140 5KSZ GCP 0.000001166 0.56256 6.02837
141 4FRZ ADP 0.000004726 0.47499 6.02837
142 1IN4 ADP 0.0004073 0.46269 6.02837
143 4ZG4 VO4 ADP 0.0008026 0.45555 6.02837
144 5LB3 ADP 0.0003006 0.43763 6.02837
145 1BH2 GSP 0.0000003987 0.48853 6.03175
146 3FWY ADP 0.00001034 0.53149 6.05096
147 3T1O GDP 0.00000000666 0.65714 6.06061
148 3RC3 ANP 0.004466 0.42947 6.09137
149 3DKP ADP 0.0003764 0.44045 6.12245
150 4U5X GNP 0.0000003441 0.60052 6.17978
151 2HF9 GSP 0.0000001663 0.62893 6.19469
152 1FP6 ADP 0.00005972 0.49488 6.34518
153 1X6V ADP 0.0005506 0.47181 6.34518
154 1Z6T ADP 0.0006349 0.45179 6.34518
155 2PL3 ADP 0.001097 0.45928 6.35593
156 1TAD ALF 0.0000001138 0.64392 6.38298
157 1TAD GDP 0.0000001138 0.64392 6.38298
158 1GOT GDP 0.00000005176 0.64376 6.38298
159 1IWE IMP 0.0002323 0.54383 6.38298
160 1W0J ADP 0.00001959 0.51631 6.38298
161 2ZFI ADP 0.00003305 0.47797 6.38298
162 3ZFD ANP 0.0001546 0.46833 6.38298
163 2CK3 ADP 0.00089 0.4535 6.38298
164 1L2T ATP 0.001355 0.44697 6.38298
165 1W0J ADP BEF 0.001148 0.4425 6.38298
166 2CK3 ANP 0.001239 0.44101 6.38298
167 4GBM A3P 0.0008178 0.41044 6.38298
168 4QM7 GTP 0.00007639 0.4646 6.43275
169 1EK0 GNP 0.0000001038 0.52759 6.47059
170 4V0K GDP 0.000000007986 0.57616 6.50888
171 2J0V GDP 0.00000001808 0.62505 6.60377
172 4M9Q GNP 0.000000002622 0.62016 6.60793
173 1JI0 ATP 0.00005297 0.5313 6.66667
174 2B8T THM 0.008019 0.40818 6.72646
175 3ZS9 ADP ALF 0.0001272 0.49796 6.73759
176 1OS1 ATP 0.0006316 0.46902 6.73759
177 1OS1 PYR 0.000682 0.46902 6.73759
178 1P9B GDP 0.005492 0.43819 6.73759
179 2WOJ ADP ALF 0.0001433 0.41733 6.73759
180 4IDN GNP 0.0008367 0.4133 6.73759
181 2C04 GCP 0.00001182 0.52891 6.85279
182 1F9V ADP 0.000006328 0.47062 6.85279
183 5IRC GDP 0.0000008775 0.56629 6.96517
184 2XT3 ADP 0.00000171 0.62187 6.97674
185 4KFU ACP 0.000003568 0.48358 7.07547
186 1OXV ANP 0.00008774 0.45235 7.08215
187 1JWY GDP 0.0000002894 0.59736 7.0922
188 1JWY ADP 0.0002467 0.45087 7.0922
189 1R6B ADP 0.0003691 0.44704 7.0922
190 1X8J A3P 0.02367 0.40719 7.0922
191 4KBF AMP 0.002344 0.40448 7.0922
192 2RCN GDP 0.0000000006235 0.66939 7.1066
193 4QOS ADP 0.0008181 0.44934 7.1066
194 3P4X ADP 0.000163 0.44505 7.1066
195 1FZQ GDP 0.0000000001214 0.78482 7.18232
196 3REF GDP 0.0000005219 0.5351 7.2165
197 2BCG GDP 0.00000001004 0.6276 7.28155
198 2VB6 ADP BEF 0.0006594 0.45944 7.38255
199 1D5C GDP 0.000000004842 0.65736 7.40741
200 3FB4 AP5 0.004267 0.44248 7.40741
201 4LC1 GDP 0.0000000003771 0.6786 7.4184
202 4D81 ADP 0.0005405 0.45252 7.42049
203 2ZPA ADP 0.000106 0.48891 7.44681
204 2W2X GSP 0.0000003211 0.6049 7.56757
205 2V7Q ATP 0.0000157 0.51183 7.57576
206 2V7Q ADP 0.0004286 0.43462 7.57576
207 3E70 GDP 0.000000522 0.56489 7.62195
208 1Z83 AP5 0.00455 0.43425 7.65306
209 1YVD GNP 0.00000002282 0.66868 7.69231
210 1OW3 GDP 0.0000003086 0.59946 7.77202
211 5L3S GNP 0.000002283 0.57416 7.80142
212 5L3W GDP 0.0000007026 0.56988 7.80142
213 4IOK ADP 0.00905 0.4409 7.80142
214 4IOK XPO 0.007647 0.44008 7.80142
215 4YS0 ADP 0.001042 0.43259 7.80142
216 4OI4 ATP 0.000993 0.45133 7.82609
217 4NU0 AP5 0.002355 0.45274 7.8341
218 2IS6 ADP 0.0001192 0.45706 7.86802
219 4DSU GDP 0.00000002131 0.67276 7.93651
220 4BQS ADP 0.000655 0.47694 7.95455
221 4BQS K2Q 0.000655 0.47694 7.95455
222 1BG2 ADP 0.0000004044 0.47709 8
223 1AQU A3P 0.008097 0.40244 8.08081
224 1YZN GNP 0.00000004411 0.53146 8.10811
225 1YQT ADP 0.00002969 0.55065 8.12183
226 1TQ4 GDP 0.000000004726 0.68756 8.15603
227 3CX8 GSP 0.00000007796 0.65159 8.15603
228 3AB3 GDP 0.00000003178 0.65022 8.15603
229 2IYL GDP 0.0000003277 0.55991 8.15603
230 4R43 GDP 0.00002714 0.53021 8.15603
231 4WZA ADP 0.0003449 0.51348 8.15603
232 4WZA ACP 0.0004727 0.50656 8.15603
233 1OYY AGS 0.01015 0.40763 8.15603
234 1FQK GDP 0.000000113 0.55146 8.16327
235 1I4D GDP 0.00000001745 0.69369 8.33333
236 1DS6 GDP 0.00000001613 0.61494 8.33333
237 1E96 GTP 0.0000008886 0.5954 8.37438
238 3M1I GTP 0.00000004228 0.65899 8.37696
239 2KIN ADP 0.0000003203 0.47899 8.40336
240 4C4P GNP 0.00000002143 0.67265 8.41121
241 1PUJ GNP 0.000000001916 0.69383 8.51064
242 3TK1 GDP 0.0000000001287 0.65952 8.51064
243 4WZ6 ATP 0.0000462 0.54014 8.51064
244 5MZN ADP 0.0002128 0.50099 8.51064
245 1F5N GNP 0.0008386 0.46003 8.51064
246 4HI0 GDP 0.00000003753 0.64696 8.54271
247 1ZJ6 G3D 0.00000000008813 0.77789 8.55615
248 3SBD GNP 0.000001078 0.49749 8.55615
249 2OFW ADX 0.0002262 0.50302 8.65385
250 1Z0K GTP 0.00000002494 0.57234 8.72093
251 1T8U A3P 0.001424 0.44034 8.82353
252 3A4M ADP 0.00001303 0.47129 8.84615
253 5O2T GSP 0.00000003099 0.53698 8.86525
254 5I34 GDP 0.000002767 0.53461 8.86525
255 4DCT GDP 0.0000000002818 0.75446 8.88325
256 1S8F GDP 0.00000001264 0.54003 8.88325
257 1NHX PEP 0.001561 0.4669 8.88325
258 1NHX FTB 0.001679 0.46638 8.88325
259 5KSP GDP 0.0000001615 0.62641 8.94737
260 2XTN GTP 0.000001908 0.57525 8.97436
261 2FJU GSP 0.0000005503 0.59434 8.98876
262 1O3Y GTP 0.000000008764 0.6819 9.03614
263 3B5J 12D 0.0001569 0.50763 9.0535
264 1LVG ADP 0.000004746 0.49195 9.09091
265 1S9D GDP 0.0000000008603 0.73196 9.14634
266 1RE0 GDP 0.0000000001206 0.68202 9.14634
267 2ZR9 DTP 0.000135 0.45466 9.21986
268 4IEE AGS 0.005269 0.42596 9.21986
269 4GDX GLU 0.01352 0.41639 9.23077
270 4P32 ADP 0.001248 0.40523 9.23695
271 1M7B GTP 0.0000002758 0.60788 9.23913
272 2C5L GTP 0.00000003074 0.5374 9.24856
273 4K81 GTP 0.00000006516 0.6528 9.35672
274 4TMK T5A 0.008781 0.42066 9.38967
275 2GK6 ADP 0.0006426 0.41748 9.39086
276 1W78 ADP 0.01309 0.40012 9.39086
277 2QEN ADP 0.0000964 0.48828 9.42857
278 3IIJ ADP 0.00002145 0.48801 9.44444
279 1M2O GNP 0.0000001151 0.63631 9.47368
280 2PEZ DAT 0.0003208 0.48747 9.49721
281 2PEZ GGZ 0.0003208 0.48747 9.49721
282 3UIE ANP 0.00006037 0.48661 9.5
283 4HSE ADP 0.0001745 0.45759 9.57447
284 3BFV ADP 0.00001658 0.5404 9.5941
285 1WQ1 GDP 0.00000001171 0.67616 9.63855
286 1CLU DBG 0.00000008437 0.67368 9.63855
287 1NVU GTP 0.00000004128 0.65947 9.63855
288 3KUD GDP 0.00000002096 0.65837 9.63855
289 3DDC GNP 0.00000006878 0.64921 9.63855
290 1NVV GNP 0.00000004189 0.53227 9.63855
291 1UKZ ADP 0.003635 0.43889 9.85222
292 3KTA AP5 0.0004705 0.45519 9.89011
293 5L3R GCP 0.000002106 0.49365 9.92908
294 1NJF ADP 0.0001475 0.48247 10
295 1NJF AGS 0.000249 0.47668 10
296 2D7D ADP 0.002502 0.412 10
297 4BAS GNP 0.00000003942 0.64912 10.0503
298 1SQ5 ADP 0.00001976 0.52949 10.0649
299 5CK5 GDP 0.00000001283 0.60806 10.1266
300 1NF3 GNP 0.000001251 0.49317 10.2564
301 2Y65 ADP 0.0000009949 0.48139 10.2837
302 5HPY GDP 0.0000002887 0.60075 10.3448
303 1ZIN AP5 0.003116 0.4491 10.4061
304 2ZJ5 ADP 0.01838 0.40672 10.4061
305 3GJ0 GDP 0.000000001539 0.73232 10.4072
306 3GJ8 GDP 0.000000003005 0.65828 10.4072
307 2CJW GDP 0.0000000003525 0.76279 10.4167
308 1GRN GDP 0.0000003127 0.59921 10.4712
309 2NGR GDP 0.00000009184 0.59677 10.4712
310 4ITR GDP 0.0000004822 0.59395 10.4712
311 1A4R GNH 0.0000001663 0.59326 10.4712
312 1A4R GDP 0.0000001095 0.58633 10.4712
313 2UZI GTP 0.0000000275 0.66495 10.5769
314 2ZPT A3P 0.02089 0.41966 10.6383
315 5BXQ GDP 0.000000001316 0.67198 10.6481
316 1IBR GNP 0.00000007442 0.64762 10.6481
317 2A9K GDP 0.00000001673 0.65589 10.6952
318 1GWN GTP 0.0000003756 0.60183 10.7317
319 2QTV GNP 0.0000002098 0.62169 10.7784
320 4HDO GNP 0.00000009784 0.52141 10.7784
321 1KO8 6PG 0.001477 0.43759 10.8571
322 1U0J ADP 0.0009902 0.41411 10.8614
323 1FNN ADP 0.0001913 0.47741 10.9929
324 5HR5 ADP 0.0003614 0.4627 10.9929
325 2FSH ANP 0.0008605 0.42372 10.9929
326 3BFX A3P 0.002522 0.40968 10.9929
327 5N69 ADP 0.0005205 0.45324 11.0553
328 4H1V GNP 0.000003657 0.55161 11.1111
329 5GJC ATP 0.0004784 0.43281 11.1675
330 3GJ7 GDP 0.000000003086 0.71794 11.2245
331 5H56 ADP 0.0005981 0.4717 11.2821
332 5H56 TYD 0.0005981 0.4717 11.2821
333 1ZC3 GNP 0.00000005751 0.6528 11.4286
334 2QZ4 ADP 0.0003017 0.46898 11.4504
335 4WOP CTP 0.0007726 0.45233 11.5556
336 3ZIA ADP 0.00007909 0.48948 11.5942
337 3ZIA ATP 0.00003836 0.48692 11.5942
338 3T12 GDP ALF 0.0000000161 0.66677 11.7647
339 1M7G ADX 0.0001149 0.50696 11.8483
340 1M7G AV2 0.000004882 0.50219 11.8483
341 1M7G ADP 0.0002007 0.49228 11.8483
342 1XTQ GDP 0.000000009762 0.67977 11.8644
343 1U8Z GDP 0.00000003025 0.65736 11.9048
344 2A5J GDP 0.000000003476 0.69279 12.0419
345 1YZG GDP 0.00000000009595 0.71799 12.2905
346 2WIC GNP 0.006703 0.44374 12.3596
347 1HE1 GDP 0.0000003958 0.55222 12.5926
348 3H4S ADP 0.000001364 0.47699 12.5926
349 1CS4 GSP 0.00000006476 0.51974 12.6904
350 1AZT GSP 0.00000003139 0.51844 12.6904
351 1B7T ADP 0.0004899 0.45944 12.8205
352 1G6H ADP 0.000009646 0.43711 12.8405
353 4HAT GNP 0.0000000991 0.64434 12.8571
354 2FFQ GSP 0.00000003025 0.66572 12.8655
355 1KK8 BEF ADP 0.0004851 0.44461 12.9496
356 1WA5 GTP 0.000000129 0.48466 13.0682
357 1Z2A GDP 0.00000001565 0.57909 13.0952
358 1Z0A GDP 0.000000003324 0.66994 13.2184
359 1MR3 G3D 0.0000000005575 0.68672 13.2597
360 1SVI GDP 0.0000000002563 0.66795 13.3333
361 2HT6 GDP 0.0000000001984 0.67427 13.4518
362 4NCN GTP 0.000000009468 0.58757 13.4518
363 3T5G GDP 0.000000002479 0.67574 13.8158
364 5TB5 GDP 0.000000001871 0.67999 14
365 5TAR GDP 0.000000004513 0.67736 14.1892
366 2A5F GTP 0.000000007054 0.68925 14.5078
367 3RLF ANP 0.001196 0.44764 14.539
368 1XX6 ADP 0.0001178 0.42229 14.6597
369 3RAB GNP 0.00000001009 0.68501 14.7929
370 4DID GDP 0.00000008038 0.59959 15.1316
371 3GJ4 GDP 0.000000001889 0.65254 15.1515
372 1G16 GDP 0.00000009405 0.63199 15.2941
373 5UWP GNP 0.00000006138 0.65401 15.3846
374 5UWU GNP 0.00000005723 0.6529 15.3846
375 5UWS GNP 0.00000006505 0.65284 15.3846
376 5DI9 GNP 0.00000006798 0.65195 15.3846
377 5UWT GNP 0.00000006598 0.65004 15.3846
378 5UWR GNP 0.00000006604 0.65002 15.3846
379 5UWI GNP 0.00000006651 0.64988 15.3846
380 5UWH GNP 0.00000004538 0.53098 15.3846
381 5UWQ GNP 0.0000000522 0.52889 15.3846
382 5UWO GNP 0.00000005115 0.52834 15.3846
383 5UWW GNP 0.00000006362 0.52773 15.3846
384 5UWJ GNP 0.00000006152 0.52708 15.3846
385 1G7S GDP 0.00000000004099 0.79333 15.4822
386 1DAR GDP 0.00000000007307 0.70648 15.4822
387 3EC1 GDP 0.000000001495 0.67109 15.4822
388 4YMU ATP 0.0002711 0.43459 15.8333
389 4B47 GDP 0.00000000000339 0.87498 15.978
390 1F6B GDP 0.000000004873 0.65137 16.1616
391 2WHX ADP 0.00007085 0.43588 16.2437
392 2JLR ANP 0.001351 0.4349 16.2437
393 1UPT GTP 0.00000001618 0.66667 16.6667
394 2OM2 GDP 0.00000002237 0.60254 16.6667
395 2GJ8 ALF GDP 0.000000003121 0.56665 16.8605
396 3A1S GDP 0.0000002797 0.58021 17.0543
397 1CXZ GSP 0.0000005507 0.59716 17.4419
398 4XTR ATP 0.0001329 0.49118 17.5115
399 4XTR ADP 0.00009434 0.49118 17.5115
400 4XVU ATP 0.0001788 0.4853 17.5115
401 3W5J GDP 0.00000008829 0.68028 17.5127
402 1KSH GDP 0.000000001941 0.705 18.2796
403 1NRJ GTP 0.00000005363 0.63996 18.3486
404 3BC1 GNP 0.00000004307 0.65597 18.4615
405 2HV8 GTP 0.00000003675 0.65915 18.75
406 4CVN ADP 0.00001853 0.55418 18.8482
407 1MKY GDP 0.00000000001981 0.72665 19.5431
408 1R4A GNP 0.000000002948 0.59179 19.6078
409 1ZD9 GDP 0.00000001572 0.66064 19.6809
410 4R98 GNH 0.0000000159 0.61637 19.9262
411 3GJ3 GDP 0.000000001764 0.65116 21.2121
412 1GUA GNP 0.00000005525 0.52792 21.5569
413 1YRB GDP 0.000000005655 0.67302 21.7557
414 1LFD GNP 0.00000004417 0.65547 21.8391
415 1Z0J GTP 0.0000000176 0.67661 22.0339
416 1X1R GDP 0.0000000524 0.5279 23.5955
417 2ODE ALF GDP 0.0000001328 0.64079 24.1135
418 5UFQ GNP 0.00000002009 0.67123 24.5902
419 2WJG GDP 0.000000000322 0.68232 26.0638
420 3PQC GDP 0.00000005214 0.61923 26.1538
421 3GJ5 GDP 0.000000003812 0.70194 26.4706
422 1J2J GTP 0.00000003185 0.57081 28.8889
423 2WJH GDP 0.0000000003251 0.69923 29.5181
424 2WJH FLC 0.000001737 0.55336 29.5181
425 5FG3 GDP 0.000000000009109 0.71879 29.6954
426 1FQJ GDP 0.0000001062 0.63248 30.9524
427 5DIF GNP 0.00000005765 0.52697 31.5789
428 2FH5 GTP 0.00000002019 0.60263 33.1776
429 3MJH GTP 0.000000008913 0.56309 35.2941
430 4RD0 GDP 0.0000000001551 0.75825 35.7868
431 2QN6 GDP 0.0000000000009894 0.9011 36.0406
432 1KK1 GNP 0.0000000000002577 0.77649 42.3858
433 1Y3A GDP 0.00000004531 0.56674 50
Pocket No.: 2; Query (leader) PDB : 4PC3; Ligand: GDP; Similar sites found: 7
This union binding pocket(no: 2) in the query (biounit: 4pc3.bio2) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5EP2 AZU 0.01307 0.40033 4.29688
2 2D2F ADP 0.0001178 0.40213 5.2
3 3HY2 ATP 0.002711 0.40235 5.45455
4 3MGB PAP 0.01243 0.40135 5.83756
5 3IUY AMP 0.005319 0.4012 6.14035
6 3B9Q MLI 0.00001694 0.40898 9.92908
7 4QRH 0O2 0.01205 0.40016 13.3333
Feedback