Receptor
PDB id Resolution Class Description Source Keywords
4R43 1.8 Å EC: 4.1.1.32 CRYSTAL STRUCTURE ANALYSIS OF MTB PEPCK MYCOBACTERIUM TUBERCULOSIS H37RV KINASE GDP BINDING LYASE
Ref.: STRUCTURAL AND FUNCTIONAL STUDIES OF PHOSPHOENOLPYR CARBOXYKINASE FROM MYCOBACTERIUM TUBERCULOSIS. PLOS ONE V. 10 20682 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PEG A:703;
A:705;
A:706;
A:704;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
106.12 C4 H10 O3 C(COC...
PO4 A:707;
Invalid;
none;
submit data
94.971 O4 P [O-]P...
GDP A:701;
Valid;
none;
Kd = 9.3 uM
443.201 C10 H15 N5 O11 P2 c1nc2...
MN A:702;
Part of Protein;
none;
submit data
54.938 Mn [Mn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4R43 1.8 Å EC: 4.1.1.32 CRYSTAL STRUCTURE ANALYSIS OF MTB PEPCK MYCOBACTERIUM TUBERCULOSIS H37RV KINASE GDP BINDING LYASE
Ref.: STRUCTURAL AND FUNCTIONAL STUDIES OF PHOSPHOENOLPYR CARBOXYKINASE FROM MYCOBACTERIUM TUBERCULOSIS. PLOS ONE V. 10 20682 2015
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 4R43 Kd = 9.3 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4R43 Kd = 9.3 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (48)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4R43 Kd = 9.3 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 4GMW - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 4GNO - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
4 5FH1 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
5 4GNL - PEP C3 H5 O6 P C=C(C(=O)O....
6 4GNP - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
7 3DT2 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
8 5V9H - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
9 3MOF Ki = 860 uM OXL C2 O4 C(=O)(C(=O....
10 4GNQ - OXL C2 O4 C(=O)(C(=O....
11 2QF2 - OAA C4 H3 O5 C(C(=O)C(=....
12 4GMM - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
13 3DT7 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
14 3DTB - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
15 5FH3 Ki = 970 uM OXL C2 O4 C(=O)(C(=O....
16 4GMU - OXL C2 O4 C(=O)(C(=O....
17 1KHF - PEP C3 H5 O6 P C=C(C(=O)O....
18 4YW8 - 1WD C6 H5 N O2 S c1cc(c(nc1....
19 4YWD - NTM C7 H5 N O4 c1cc(c(nc1....
20 5FH4 Ki = 174 uM SPV C3 H4 O6 S C(C(=O)C(=....
21 2RKD Ki = 1.9 mM 3PP C3 H7 O5 P C(CP(=O)(O....
22 3MOH Ki = 1460 uM PGA C2 H5 O6 P C(C(=O)O)O....
23 2RK8 Ki = 230 uM PPF C H3 O5 P C(=O)(O)P(....
24 5V9G Ki = 441 uM OXL C2 O4 C(=O)(C(=O....
25 5FH5 - PGA C2 H5 O6 P C(C(=O)O)O....
26 5V9F Ki = 37 uM SPV C3 H4 O6 S C(C(=O)C(=....
27 4YW9 Ki = 45 uM 1WD C6 H5 N O2 S c1cc(c(nc1....
28 3MOE Ki = 50 uM SPV C3 H4 O6 S C(C(=O)C(=....
29 2RK7 Ki = 89 uM OXL C2 O4 C(=O)(C(=O....
30 4GNM - OXL C2 O4 C(=O)(C(=O....
31 2QF1 - OAA C4 H3 O5 C(C(=O)C(=....
32 5FH2 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
33 2RKA Ki = 1 mM PGA C2 H5 O6 P C(C(=O)O)O....
34 1M51 ic50 = 18.8 uM TSX C21 H25 N5 O3 CCCCN1c2c(....
35 1NHX ic50 ~ 2.11 uM FTB C25 H26 F N5 O3 CCCCN1c2c(....
36 4GMZ - SPV C3 H4 O6 S C(C(=O)C(=....
37 4OX2 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
38 5FH0 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
39 5V97 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
40 1KHB - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
41 3DT4 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
42 2RKE Ki = 82.5 uM SAT C2 H4 O5 S C(C(=O)O)S....
43 2QEY - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
44 4YWB - OXD C2 H2 O4 C(=O)(C(=O....
45 2GMV ic50 = 0.63 uM UN8 C27 H28 F N7 O4 S CCCCN1c2c(....
46 1KHE - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
47 2QZY - PEP C3 H5 O6 P C=C(C(=O)O....
48 2FAH Ki = 50 mM MLA C3 H4 O4 C(C(=O)O)C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4R43; Ligand: GDP; Similar sites found: 561
This union binding pocket(no: 1) in the query (biounit: 4r43.bio1) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3COB ADP 0.000007042 0.49254 1.08401
2 5XDR ADP 0.001384 0.444 1.11821
3 3NKS FAD 0.04535 0.42536 1.25786
4 5I0H ADP BEF 0.0003277 0.48571 1.27796
5 5HR5 ADP 0.00007432 0.51202 1.31827
6 1IHU AF3 0.0001344 0.50669 1.52801
7 1IHU ADP 0.0001485 0.50669 1.52801
8 3FYH ADP 0.0009011 0.47021 1.5528
9 1JWY GDP 0.00009542 0.50421 1.59744
10 1JWY ADP 0.0001092 0.49581 1.59744
11 4A4Z ANP 0.003254 0.424 1.59744
12 3V2U ATP 0.001856 0.45114 1.59817
13 4H1V GNP 0.001004 0.45786 1.62602
14 2J5V PCA 0.03783 0.40005 1.63488
15 2I4I AMP 0.00822 0.41405 1.67866
16 1Z6T ADP 0.00016 0.49607 1.69205
17 2ZPT A3P 0.008927 0.45006 1.69492
18 1KK1 GNP 0.00002927 0.51033 1.70732
19 2ZEJ GDP 0.00006607 0.53 1.75719
20 4FRZ ADP 0.00001971 0.48982 1.75719
21 1SVM ATP 0.006843 0.45133 1.85676
22 3EWA ANP 0.0006168 0.4577 1.86335
23 2GDJ ANP 0.0007628 0.45339 1.89394
24 4QRH 0O2 0.006675 0.42223 1.90476
25 2XTZ GSP 0.0004294 0.48789 1.9774
26 2ZR9 DTP 0.0003196 0.47101 2.00573
27 4AG5 ADP 0.0001137 0.50992 2.04082
28 1W4R TTP 0.002641 0.45204 2.05128
29 4LJ9 ACP 0.00003394 0.5164 2.0649
30 1X6V ADP 0.00004777 0.54075 2.07668
31 1R6B ADP 0.00002889 0.52293 2.07668
32 2ZPA ADP 0.000766 0.46572 2.07668
33 1P72 ADP 0.0002973 0.50575 2.09581
34 2BIF SIN 0.000292 0.5192 2.1322
35 2BIF ANP 0.0001727 0.5192 2.1322
36 2ORV 4TA 0.01366 0.41351 2.13675
37 1NST A3P 0.0004915 0.47273 2.15385
38 1TAD ALF 0.0003472 0.49764 2.16049
39 1TAD GDP 0.0003472 0.49764 2.16049
40 3TBK ANP 0.0002722 0.46048 2.16216
41 2Q2Y ADP 0.0004974 0.50367 2.17984
42 2Q2Y MKR 0.0004712 0.50367 2.17984
43 4ZNL BEF ADP 0.00007001 0.50487 2.18978
44 2CHG ANP 0.0001807 0.49354 2.21239
45 4WOP CTP 0.0004524 0.47892 2.22222
46 2VF7 ADP 0.0008361 0.45429 2.23642
47 2FNA ADP 0.0001669 0.5021 2.2409
48 4FCW ADP 0.00001984 0.53059 2.2508
49 4LX0 BEF GDP 0.000101 0.52086 2.25989
50 3GJ5 GDP 0.00007108 0.50457 2.26244
51 3GJ3 GDP 0.00006398 0.50357 2.26244
52 3GJ0 GDP 0.00006834 0.50223 2.26244
53 5GJC ATP 0.001746 0.43662 2.26244
54 4XDA ADP 0.01904 0.4175 2.26537
55 5JCZ GDP 0.00006807 0.51637 2.267
56 3ZFD ANP 0.0002813 0.47926 2.2792
57 1IBR GNP 0.001429 0.46374 2.31481
58 4LYA ATP 0.00002775 0.52375 2.32558
59 4TMK T5A 0.02308 0.411 2.34742
60 4XGU ADP 0.001719 0.44667 2.35849
61 3QKT ANP 0.002904 0.44519 2.35988
62 2D7C GTP 0.00006497 0.52841 2.39521
63 4NCN GTP 0.0007194 0.47315 2.39617
64 5MZN ADP 0.0002243 0.46101 2.39617
65 2XAU ADP 0.0008826 0.45577 2.39617
66 1V8K ANP 0.0003019 0.47216 2.43902
67 2ZFI ADP 0.00005718 0.50584 2.45902
68 1XP8 AGS 0.01927 0.45269 2.45902
69 2C78 GNP 0.0001843 0.5 2.46914
70 2C77 GNP 0.0001956 0.49657 2.46914
71 1JI0 ATP 0.0005606 0.4719 2.5
72 1LVG ADP 0.00004118 0.49473 2.52525
73 3WY9 GDP 0.00001417 0.52366 2.53456
74 3WYA GDP 0.00002834 0.52005 2.53456
75 1L2T ATP 0.001199 0.4641 2.55319
76 1QHG ATP 0.003635 0.42893 2.55591
77 2VVG ADP 0.000002301 0.49205 2.57143
78 1OS1 PYR 0.0002734 0.50447 2.59259
79 1OS1 ATP 0.0002536 0.50447 2.59259
80 2OBM ADP 0.0001919 0.4377 2.59366
81 1SQ5 ADP 0.00002961 0.52242 2.5974
82 4B7P 9UN 0.0482 0.4054 2.6087
83 3CNL GNP 0.00002836 0.51065 2.67176
84 1ZJ6 G3D 0.03289 0.40416 2.6738
85 5L3V GDP 0.0001606 0.49077 2.67559
86 5HCN GCP 0.0002046 0.48301 2.68199
87 1G7S GDP 0.00003883 0.50122 2.6936
88 1F5N GNP 0.0005631 0.48382 2.7027
89 5LTJ ADP 0.0005768 0.46186 2.71565
90 4YS0 ADP 0.002102 0.44248 2.71565
91 2JLR ANP 0.002935 0.43336 2.71565
92 1E2K TMC 0.0002742 0.51706 2.71903
93 4YMU ATP 0.000783 0.44626 2.72727
94 2WHX ADP 0.0005481 0.43483 2.75081
95 4HSE ADP 0.00009423 0.49881 2.77078
96 1YQT ADP 0.00004876 0.47415 2.7881
97 4TTQ ATP 0.0000893 0.49682 2.7907
98 1NJF ADP 0.00004257 0.52619 2.8
99 1NJF AGS 0.00008509 0.51635 2.8
100 4ZKD GDP 0.0008523 0.47489 2.80561
101 4P32 ADP 0.002065 0.44888 2.81124
102 5GOE GDP 0.00005241 0.51377 2.8436
103 4IDN GNP 0.0003659 0.4855 2.84464
104 3NKV GNP 0.0001164 0.5159 2.85714
105 5M7P ADP 0.00008547 0.51161 2.8754
106 4GOX A3P 0.0001493 0.50658 2.8754
107 1JJ7 ADP 0.0000313 0.45564 2.8754
108 3B5J 12D 0.001698 0.42522 2.88066
109 2GK6 ADP 0.001498 0.42438 2.88462
110 4LPS GDP 0.0001226 0.49345 2.89256
111 2XT3 ADP 0.000006481 0.49407 2.90698
112 5XCO GDP 0.00006996 0.51063 2.92398
113 5WDR GNP 0.0003547 0.49379 2.92398
114 1T8U A3P 0.0006032 0.47287 2.94118
115 2IXE ATP 0.002015 0.4494 2.95203
116 1U8Z GDP 0.0002333 0.49709 2.97619
117 1YTM ATP 0.00004934 0.44971 3.00752
118 2Y65 ADP 0.000003844 0.50226 3.0137
119 5VGR GDP 0.0001398 0.49887 3.01624
120 2Z5F A3P 0.001398 0.45518 3.02013
121 1OIV GDP 0.00002688 0.54735 3.03514
122 1OIX GDP 0.00006005 0.5301 3.03514
123 4PJ3 ANP 0.0005352 0.46856 3.03514
124 3GJ7 GDP 0.00008963 0.49674 3.06122
125 4YDS ATP 0.00006193 0.48287 3.07018
126 3IUY AMP 0.008559 0.40437 3.07018
127 1SVI GDP 0.000005324 0.54248 3.07692
128 3PQC GDP 0.00002898 0.52594 3.07692
129 1D5C GDP 0.00004827 0.521 3.08642
130 5MEX SZZ 0.003797 0.45577 3.10559
131 5MEX PAP 0.001411 0.45293 3.10559
132 2BEK ATP 0.002284 0.46714 3.11284
133 2A9K GDP 0.0001728 0.49447 3.13901
134 2B8T THM 0.01129 0.41285 3.13901
135 5CK5 GDP 0.00004974 0.50119 3.16456
136 2IYL GDP 0.00005193 0.50779 3.16901
137 2IS6 ADP 0.0003085 0.47172 3.19489
138 1ZRH A3P 0.007204 0.42062 3.19489
139 1VHT BA3 0.001321 0.44748 3.21101
140 3EC1 GDP 0.00002472 0.52611 3.25203
141 1M7B GTP 0.0001358 0.50424 3.26087
142 1IN4 ADP 0.00007384 0.51467 3.29341
143 3BFV ADP 0.0008007 0.45241 3.32103
144 1YZG GDP 0.00008233 0.50157 3.35196
145 1WA5 GTP 0.001463 0.46931 3.35463
146 2CE7 ADP 0.03553 0.40448 3.36134
147 2WIC GNP 0.00008053 0.50202 3.37079
148 5LB3 ADP 0.0003032 0.46517 3.37079
149 3E5H GNP 0.004637 0.43679 3.37079
150 4RD0 GDP 0.0001283 0.50766 3.37349
151 3LRE ADP 0.000001843 0.49497 3.38028
152 1XTQ GDP 0.0001793 0.50269 3.38983
153 3ZQ6 ADP ALF 0.0002913 0.49802 3.39506
154 4IOK XPO 0.01759 0.43275 3.39893
155 4IOK ADP 0.02135 0.43245 3.39893
156 4GBM A3P 0.0008383 0.46989 3.40557
157 2AWN ADP 0.000002987 0.47346 3.41207
158 3RLF ANP 0.0007237 0.47302 3.41207
159 3W5J GDP 0.00002707 0.47235 3.43137
160 1RYH GNP 0.00009324 0.50194 3.44828
161 4WZ6 ATP 0.0002652 0.44879 3.44828
162 1UKZ ADP 0.005521 0.44274 3.44828
163 1R0X ATP 0.0008928 0.44211 3.4965
164 3FWY ADP 0.0000697 0.51335 3.50318
165 5K5Z ANP 0.002088 0.45225 3.50318
166 2F9L GDP 0.00004493 0.5321 3.51759
167 3Q85 GNP 0.00001822 0.529 3.5503
168 2ZTS ADP 0.02937 0.41441 3.58566
169 5H56 TYD 0.0009915 0.47636 3.58974
170 5H56 ADP 0.0009915 0.47636 3.58974
171 2WKQ GTP 0.00029 0.49246 3.61446
172 3P4X ADP 0.0000781 0.49049 3.63196
173 3DKP ADP 0.001213 0.444 3.67347
174 5JCP GDP ALF 0.0001715 0.44443 3.67412
175 1D2N ANP 0.00135 0.45591 3.67647
176 1H65 GDP 0.0001164 0.50972 3.7037
177 1G3M PCQ 0.008755 0.43811 3.7415
178 1G3M A3P 0.008755 0.43811 3.7415
179 3SBD GNP 0.0003673 0.49124 3.74332
180 3VMF GTP 0.0002198 0.50225 3.75335
181 1G41 ADP 0.0162 0.46393 3.82883
182 4ZG4 VO4 ADP 0.0004852 0.48152 3.83387
183 4NON GDP 0.0001257 0.51796 3.84615
184 2G77 GDP 0.00004226 0.52376 3.90244
185 1OE0 TTP 0.01838 0.40852 3.91304
186 1GOJ ADP 0.000003227 0.48757 3.94366
187 2WOJ ADP ALF 0.0001403 0.51377 3.9548
188 3ZS9 ADP ALF 0.0001882 0.50744 3.9548
189 1S8F GDP 0.01256 0.44496 3.9548
190 1WF3 GNP 0.000144 0.51321 3.98671
191 1RJ9 GCP 0.0008707 0.49445 4
192 2C04 GCP 0.001266 0.45303 4.0404
193 5TSH ANP 0.00002614 0.52169 4.08163
194 5TSH ADP 0.0000144 0.49832 4.08163
195 4QM7 GTP 0.0004526 0.46396 4.09357
196 3QXC ATP 0.01634 0.43739 4.13223
197 5KSZ GCP 0.0001399 0.49361 4.24528
198 2XTN GTP 0.00006424 0.5245 4.2735
199 1X8J A3P 0.00592 0.44899 4.2735
200 5O2T GSP 0.0003725 0.49273 4.27807
201 4V03 ADP 0.0004183 0.47111 4.28016
202 5WRJ A3P 0.0002719 0.4958 4.29043
203 4PFO ADP 0.0002507 0.49943 4.3131
204 1WDT GTP 0.001118 0.4578 4.3131
205 5MVR ADP 0.0001309 0.48907 4.32099
206 4D0N GDP 0.00005322 0.5073 4.32432
207 3LXR GDP 0.0000797 0.50516 4.32432
208 2FH5 GTP 0.0004704 0.4781 4.32432
209 3KJI ADP 0.03174 0.409 4.33071
210 1VG0 GDP 0.00005107 0.51714 4.34783
211 1VG8 GNP 0.0001425 0.51344 4.34783
212 1KMQ GNP 0.0002839 0.49291 4.34783
213 4TMZ GSP 0.0007168 0.47322 4.34783
214 3DZD ADP 0.001257 0.45091 4.34783
215 2ZE7 AMP 0.01172 0.41683 4.34783
216 2ZE7 DST 0.01253 0.41683 4.34783
217 2PZE ATP 0.000136 0.44749 4.36681
218 3QF7 ANP 0.001409 0.45296 4.38356
219 4M9Q GNP 0.0002373 0.49466 4.40529
220 4R98 GNH 0.00001409 0.53419 4.42804
221 4XOI GTP 0.0003531 0.49022 4.44444
222 2RCN GDP 0.00002854 0.51991 4.46927
223 5IRN ADP 0.000066 0.51183 4.47284
224 5J1J ANP 0.000389 0.48622 4.47284
225 5N69 ADP 0.0004454 0.47236 4.47284
226 4IEE AGS 0.009449 0.40676 4.4898
227 1U0J ADP 0.001873 0.42905 4.49438
228 3EZ2 ADP 0.001621 0.43089 4.52261
229 4DCT GDP 0.00005727 0.50897 4.60526
230 1ZIN AP5 0.003616 0.45907 4.60829
231 1PUJ GNP 0.00006982 0.51067 4.60993
232 2CJW GDP 0.00003115 0.51814 4.6875
233 1R2Q GNP 0.0001273 0.52742 4.70588
234 4DSU GDP 0.0001535 0.51184 4.7619
235 3B7G ANP 0.001042 0.4498 4.78261
236 2WJG GDP 0.00002845 0.51998 4.78723
237 1KAO GDP 0.0001142 0.50309 4.79042
238 1NY5 ADP 0.000276 0.48473 4.79233
239 2D7D ADP 0.00174 0.4367 4.79233
240 2OFW ADX 0.00007559 0.54468 4.80769
241 4E03 ADP 0.002805 0.42958 4.85437
242 2IL4 COA 0.006147 0.41805 4.85437
243 4PPF FLC 0.00002983 0.44213 4.85714
244 4EU7 CIT 0.03408 0.40831 4.86381
245 4EU7 COA 0.03711 0.40543 4.86381
246 1VG1 GDP 0.00002799 0.52357 4.86486
247 1VG9 GDP 0.00005384 0.51023 4.86486
248 2HF9 GSP 0.0009674 0.47045 4.86726
249 1DAK DPU 0.01196 0.46088 4.91071
250 1DAK ADP 0.01196 0.46088 4.91071
251 1XKV ATP 0.0001878 0.48756 4.91493
252 1ION ADP 0.0006557 0.46188 4.93827
253 1OW3 GDP 0.000167 0.49518 4.95868
254 3DEF GDP 0.0001179 0.49985 4.96183
255 1MKY GDP 0.00002396 0.52345 5.01139
256 2C9O ADP 0.0129 0.45067 5.04386
257 1UAD GNP 0.0003325 0.49338 5.05051
258 1AQU A3P 0.002445 0.43934 5.05051
259 1G3Q ADP 0.0003977 0.46944 5.06329
260 4MKG AP5 0.004704 0.45314 5.06912
261 5FTB ANP 0.0005053 0.44062 5.08083
262 2HT6 GDP 0.00004085 0.50416 5.17241
263 3SXN COA 0.01602 0.4054 5.21327
264 5L3W GDP 0.0001538 0.49166 5.22876
265 1Z0K GTP 0.0002343 0.49699 5.23256
266 2GJ8 ALF GDP 0.0003598 0.49348 5.23256
267 5KSP GDP 0.00006458 0.50652 5.26316
268 4J0Q GDP 0.00000805 0.53441 5.31178
269 4P3Y GDP 0.00001062 0.52928 5.32995
270 4G5G GDP 0.0000234 0.52393 5.32995
271 3U6B GDP 0.00001518 0.52261 5.32995
272 3U6K GDP 0.00002687 0.52113 5.32995
273 5JBQ GDP 0.00002812 0.52021 5.32995
274 1JJV ATP 0.00005413 0.47335 5.33981
275 4LC1 GDP 0.00004404 0.51113 5.34125
276 1D8T GDP 0.00002282 0.52444 5.34351
277 2BVN GNP 0.00008225 0.50728 5.34351
278 1Z2A GDP 0.0002593 0.41266 5.35714
279 1MH1 GNP 0.0003058 0.49698 5.37634
280 1YZN GNP 0.0002166 0.50442 5.40541
281 5L3S GNP 0.0002424 0.49826 5.40541
282 5DI3 GNP 0.000269 0.492 5.40541
283 1F2U ATP 0.002859 0.44879 5.40541
284 2WJH GDP 0.00009781 0.49805 5.42169
285 3Q72 GNP 0.00007683 0.4916 5.42169
286 2WJH FLC 0.0001881 0.48752 5.42169
287 1Y63 ADP 0.00005999 0.50487 5.43478
288 1G4U GDP 0.000211 0.4927 5.43478
289 1FQK GDP 0.0004239 0.48439 5.44218
290 1T5C ADP 0.000001017 0.50459 5.44413
291 2DPY ADP 0.000008186 0.5622 5.47945
292 2BCG GDP 0.0000806 0.51283 5.51876
293 3DC4 ADP 0.00004765 0.48815 5.52326
294 3CPJ GDP 0.00001616 0.54093 5.54324
295 1F6B GDP 0.0001469 0.48975 5.55556
296 3WXM GTP 0.0004552 0.48663 5.58511
297 2PEZ DAT 0.00005083 0.54456 5.58659
298 2PEZ GGZ 0.00005083 0.54456 5.58659
299 1Z83 AP5 0.004791 0.44587 5.61225
300 1SVK ALF GDP 0.0007963 0.48115 5.66572
301 1NRJ GTP 0.0001355 0.50429 5.6962
302 4DID GDP 0.00007752 0.5028 5.69948
303 1KO8 6PG 0.0007834 0.46525 5.71429
304 4LHW GNP 0.0001333 0.51298 5.74713
305 3IO3 ADP 0.017 0.42694 5.74713
306 1A4R GNH 0.0000959 0.50672 5.75916
307 2NGR GDP 0.00007673 0.50301 5.75916
308 1A4R GDP 0.0001606 0.49841 5.75916
309 4ITR GDP 0.0001631 0.49808 5.75916
310 1XX6 ADP 0.000232 0.44898 5.75916
311 1TQ4 GDP 0.00001672 0.54831 5.81114
312 5G41 AP5 0.005534 0.45439 5.8296
313 5M04 GDP 0.00004963 0.50093 5.83333
314 4P4T GDP 0.02321 0.41981 5.83333
315 1UPT GTP 0.0003102 0.48899 5.84795
316 1EK0 GNP 0.0002231 0.50194 5.88235
317 2QEN ADP 0.00003158 0.52982 5.91054
318 1GRN GDP 0.00011 0.50386 5.91133
319 3T5G GDP 0.00009295 0.502 5.92105
320 4HDO GNP 0.0005103 0.48594 5.98802
321 4HDQ GNP 0.0006275 0.48148 5.98802
322 3X1Z GNP 0.0008093 0.47766 5.98802
323 3TNF GNP 0.00006845 0.53112 5.98958
324 4NU0 AP5 0.003456 0.45788 5.99078
325 3UIE ANP 0.00002155 0.53202 6
326 5TB5 GDP 0.00006988 0.50786 6
327 3BER AMP 0.005738 0.4125 6.0241
328 2GWH A3P 0.002117 0.44233 6.04027
329 1TX4 ALF GDP 0.0002725 0.40695 6.06061
330 1ZCB GDP 0.0002339 0.50092 6.07735
331 4YC7 GNP 0.0002015 0.49812 6.07735
332 3AB3 GDP 0.0003261 0.48581 6.07735
333 1Y3A GDP 0.0001375 0.50833 6.07903
334 3BFX A3P 0.000512 0.47415 6.08108
335 5TAR GDP 0.00009525 0.46397 6.08108
336 5EE5 GTP 0.0003031 0.48948 6.10329
337 4KFU ACP 0.00007448 0.47104 6.13208
338 2OM2 GDP 0.0001968 0.42713 6.15385
339 4R2I ANP 0.003499 0.40911 6.19048
340 1I4D GDP 0.00002567 0.51193 6.25
341 1DS6 GDP 0.00004298 0.51162 6.25
342 2HCJ GDP 0.00001531 0.52239 6.26866
343 4BFW ZVW 0.0004831 0.50433 6.28931
344 3GJX GTP 0.002137 0.45506 6.30137
345 2RGX AP5 0.008507 0.44177 6.31068
346 5L3R GCP 0.0002519 0.49744 6.31229
347 5TIV A3P 0.001427 0.48325 6.32411
348 1BH2 GSP 0.0008759 0.47753 6.34921
349 2C5L GTP 0.000453 0.48851 6.35838
350 2OZE AGS 0.01413 0.43116 6.37584
351 3SFV GDP 0.00008813 0.51334 6.39535
352 3E70 GDP 0.000247 0.47916 6.40244
353 4K81 GTP 0.0004124 0.49225 6.43275
354 1SKQ GDP 0.000008719 0.53274 6.43678
355 5IRC GDP 0.0003552 0.47447 6.46766
356 1G16 GDP 0.0001135 0.51026 6.47059
357 4DKX GDP 0.00006933 0.50194 6.48148
358 3TMK T5A 0.001284 0.46922 6.48148
359 4PX9 ADP 0.000266 0.4659 6.50685
360 3GJ8 GDP 0.00009882 0.49784 6.52174
361 4BAS GNP 0.0002522 0.49337 6.53266
362 3A4M ADP 0.00003134 0.49743 6.53846
363 1ZUI SKM 0.0009959 0.4832 6.54762
364 5WRI A3P 0.0002734 0.49167 6.5625
365 4CVN ADP 0.000005366 0.53023 6.56934
366 5I34 GDP 0.002889 0.42898 6.57596
367 1CLU DBG 0.0006225 0.50094 6.62651
368 1WQ1 GDP 0.0002011 0.50024 6.62651
369 1NVV GNP 0.0002713 0.49956 6.62651
370 1NVU GTP 0.0002962 0.49766 6.62651
371 2UZI GTP 0.0003624 0.49153 6.62651
372 3KUD GDP 0.000313 0.48667 6.62651
373 3IIJ ADP 0.00007995 0.49906 6.66667
374 3H4S ADP 0.000006385 0.49383 6.66667
375 2FJU GSP 0.0001891 0.49728 6.74157
376 3DOE GTP 0.0004362 0.48379 6.77083
377 1OXV ANP 0.0003345 0.46227 6.79887
378 3NHB ADP 0.00009016 0.46639 6.86275
379 1DAR GDP 0.00005798 0.50556 6.86901
380 2BME GNP 0.0003045 0.49526 6.98925
381 1KSH GDP 0.000349 0.48438 6.98925
382 1G6H ADP 0.00007248 0.44382 7.00389
383 3RWO GDP 0.00004977 0.53413 7.02703
384 1NF3 GNP 0.0002441 0.5 7.03125
385 1ZC3 GNP 0.000328 0.49547 7.07965
386 3RAB GNP 0.0001343 0.51283 7.10059
387 5IRR GSP 0.0005154 0.47825 7.14286
388 4HAT GNP 0.00143 0.46533 7.14286
389 5FG3 GDP 0.00002565 0.51274 7.1885
390 2FSH ANP 0.0009104 0.44305 7.1885
391 5SZH GNP 0.00008066 0.5257 7.18954
392 3MGB PAP 0.002648 0.44172 7.21003
393 5E95 GDP 0.0001108 0.50372 7.2165
394 1YRB GDP 0.00005337 0.51622 7.25191
395 4U5X GNP 0.0001801 0.49602 7.30337
396 2B8W ALF 5GP 0.0004213 0.48645 7.31707
397 5BYK A3P 0.001067 0.48536 7.33591
398 5BYK OAQ 0.001067 0.48536 7.33591
399 3DDC GNP 0.0003377 0.49484 7.36196
400 1S3G AP5 0.007844 0.44162 7.37327
401 2VB6 ADP BEF 0.0003062 0.49131 7.38255
402 4BQS ADP 0.0007341 0.48997 7.38636
403 4BQS K2Q 0.0007341 0.48997 7.38636
404 5KUT GDP 0.00001513 0.53612 7.40741
405 4GOJ GNP 0.0001859 0.49982 7.40741
406 1AZT GSP 0.0002078 0.5088 7.46269
407 4C4P GNP 0.00007892 0.52617 7.47664
408 3BD9 A3P 0.0003649 0.4712 7.5
409 3FVQ ATP 0.001926 0.44843 7.52089
410 2QG6 NMN 0.0007591 0.47904 7.53769
411 1YZQ GNP 0.0003315 0.49524 7.64706
412 1YVD GNP 0.0001655 0.50835 7.69231
413 1BG2 ADP 0.000002994 0.48966 7.69231
414 1FZQ GDP 0.00005099 0.50816 7.73481
415 5HPY GDP 0.000148 0.49769 7.75862
416 2W83 GTP 0.0002503 0.4956 7.79221
417 3QBT GNP 0.0001151 0.41017 7.85714
418 1FP6 ADP 0.00009345 0.50465 7.95848
419 4B47 GDP 0.00001207 0.52673 7.98898
420 4PC3 GDP 0.00002714 0.53021 8.15603
421 4XSH GSP 0.0001609 0.49837 8.21918
422 1FNN ADP 0.0002741 0.48722 8.22622
423 1Z08 GNP 0.0009309 0.46767 8.23529
424 3TKL GTP 0.00007666 0.52284 8.2397
425 1KY3 GDP 0.00006063 0.51359 8.24176
426 1W5T ANP 0.0003382 0.48504 8.25243
427 1W5T ADP 0.0005142 0.47178 8.25243
428 2A5F GTP 0.0002224 0.50009 8.29016
429 4WZA ACP 0.0007334 0.51231 8.33333
430 4WZA ADP 0.0007334 0.51231 8.33333
431 1UJ2 ADP 0.008676 0.45222 8.33333
432 1UJ2 C5P 0.02325 0.42909 8.33333
433 1VKJ A3P 0.001141 0.45946 8.42105
434 1Z06 GNP 0.00007707 0.52273 8.46561
435 5BQ5 ADP BEF 0.0001179 0.49713 8.46561
436 2X77 GDP 0.0001557 0.48857 8.46561
437 2PL3 ADP 0.0006599 0.45008 8.47458
438 3TK1 GDP 0.000006452 0.52785 8.48485
439 4U00 ADP 0.00001609 0.46579 8.60656
440 3BOS CDP 0.0001077 0.49302 8.67769
441 4MKF AP5 0.004164 0.45694 8.75576
442 3KTA AP5 0.000236 0.4855 8.79121
443 5UWH GNP 0.001044 0.47051 8.86076
444 5UWI GNP 0.001187 0.46775 8.86076
445 5UWO GNP 0.001197 0.46755 8.86076
446 5UWP GNP 0.001304 0.46733 8.86076
447 5UWS GNP 0.001317 0.46711 8.86076
448 5UWU GNP 0.001271 0.46626 8.86076
449 5DIF GNP 0.001307 0.46567 8.86076
450 5UWT GNP 0.001349 0.46498 8.86076
451 5UWW GNP 0.001371 0.46463 8.86076
452 5DI9 GNP 0.001632 0.46247 8.86076
453 5DHF GNP 0.001538 0.46216 8.86076
454 4V0K GDP 0.0002711 0.49587 8.87574
455 4X8O AP5 0.009545 0.44193 8.8785
456 2J0V GDP 0.00004032 0.51613 8.96226
457 2GAG NAD 0.02763 0.41215 9.04762
458 4RZ3 ADP 0.0004463 0.47473 9.15254
459 1Q20 A3P 0.00808 0.43431 9.36455
460 1Q20 PLO 0.00808 0.43431 9.36455
461 2HV8 GTP 0.0000738 0.52567 9.375
462 5BXQ GDP 0.000175 0.48618 9.44882
463 2EW1 GNP 0.0002374 0.49671 9.45274
464 1F9V ADP 0.00001808 0.49235 9.51009
465 1HE1 GDP 0.0002493 0.42394 9.62963
466 2W2X GSP 0.0002699 0.48979 9.67742
467 1QF9 ADP 0.00853 0.43656 9.79381
468 1QF9 ALF 0.00853 0.43656 9.79381
469 1QF9 C5P 0.00853 0.43656 9.79381
470 5UFQ GNP 0.0002201 0.50223 9.83607
471 3PCR GTP 0.00011 0.51306 9.87654
472 4KAX GTP 0.0002107 0.49717 10.0592
473 1D2E GDP 0.00004286 0.52076 10.0756
474 3T1O GDP 0.000105 0.49951 10.101
475 3T12 GDP ALF 0.0003544 0.48618 10.101
476 1ZD9 GDP 0.0001339 0.50222 10.1064
477 4KVG GTP 0.000398 0.48952 10.119
478 4ITM ATP 0.01936 0.40597 10.1587
479 1Z0J GTP 0.0001516 0.5121 10.1695
480 1GWN GTP 0.0001402 0.50358 10.2439
481 2JAQ DCP 0.0166 0.40626 10.2439
482 3Q9L ATP 0.0008379 0.46163 10.3846
483 2KIN ADP 0.000001961 0.49529 10.5042
484 4ZI2 GNP 0.0002385 0.49455 10.5263
485 2CBZ ATP 0.00001876 0.56146 10.5485
486 4D81 ADP 0.00007257 0.50987 10.6007
487 1Z0F GDP 0.00004946 0.51196 10.6145
488 3REF GDP 0.0001253 0.50817 10.8247
489 1E96 GTP 0.0002418 0.50021 10.8374
490 3CX8 GSP 0.0005277 0.48855 10.8374
491 2W58 ADP 0.00002026 0.46254 10.8911
492 3H86 AP5 0.00266 0.46014 10.9375
493 2GCO GNP 0.0001516 0.4972 10.9453
494 2GCN GDP 0.0002239 0.49589 10.9453
495 2FFQ GSP 0.0004158 0.49036 11.1111
496 4QOS ADP 0.0003011 0.47787 11.3208
497 3WYF GTP 0.0009241 0.47479 11.4155
498 3M1I GTP 0.001048 0.47043 11.4155
499 1LFD GNP 0.0002697 0.49787 11.4943
500 1R4A GNP 0.0003969 0.48772 11.5152
501 4D0G GTP 0.0001681 0.50195 11.5942
502 1MR3 G3D 0.0001085 0.49593 11.6022
503 2EFE GNH 0.0002751 0.48232 11.6022
504 5UQW GDP 0.0001244 0.51251 11.6402
505 5K04 COA 0.01228 0.41272 11.7647
506 5X40 ACP 0.003065 0.44232 11.9863
507 3FB4 AP5 0.005706 0.44879 12.037
508 2A5J GDP 0.00005057 0.48617 12.0419
509 5KDO GDP 0.0002036 0.49572 12.1622
510 1B7T ADP 0.00009296 0.502 12.1795
511 1KK8 BEF ADP 0.0001348 0.49963 12.3377
512 3N5C GDP 0.00003308 0.51692 12.3457
513 1TU3 GNP 0.00005949 0.5303 12.6582
514 1GP2 GDP 0.0002027 0.41353 12.6761
515 1J99 AND 0.01638 0.41864 12.9693
516 2QZ4 ADP 0.0001944 0.48685 12.9771
517 1M2O GNP 0.0001889 0.50551 13.1579
518 4YLG GDP 0.00007993 0.51051 13.2948
519 4HI0 GDP 0.00003233 0.53444 13.3858
520 3WYG GTP 0.001336 0.46681 13.7363
521 4OI4 ATP 0.00327 0.44094 13.913
522 1W0J ADP 0.0001026 0.50271 13.9216
523 2V7Q ATP 0.0001432 0.49313 13.9216
524 1W0J ADP BEF 0.000313 0.48445 13.9216
525 2CK3 ANP 0.000328 0.48347 13.9216
526 2CK3 ADP 0.000574 0.47795 13.9216
527 2V7Q ADP 0.0002844 0.47337 13.9216
528 3A1S GDP 0.00001529 0.5359 13.9535
529 5H67 ATP 0.002016 0.43633 14.3617
530 1G7C 5GP 0.0009302 0.44938 14.8936
531 2QTV GNP 0.0004005 0.48753 14.9701
532 1CXZ GSP 0.0003121 0.48886 15.1163
533 5J1S ATP 0.0003359 0.49129 15.1408
534 3VX3 ADP 0.0009361 0.46152 15.3226
535 1M7G AV2 0.00004573 0.50191 16.1137
536 1M7G ADX 0.0003304 0.50191 16.1137
537 1M7G ADP 0.0003448 0.4978 16.1137
538 4XTR ADP 0.00007224 0.51513 16.129
539 4XTR ATP 0.00009985 0.51513 16.129
540 4XVU ATP 0.0001146 0.51219 16.129
541 1FQJ GDP 0.0003309 0.48965 16.6667
542 1GOT GDP 0.0002634 0.49245 17.8082
543 3GJ4 GDP 0.00004984 0.50862 18.1818
544 3BC1 GNP 0.000132 0.51319 18.6441
545 1HTW ADP 0.0002886 0.47598 19.6203
546 3AQ4 GDP 0.00005913 0.50832 20.6522
547 1Z0A GDP 0.00004573 0.51657 20.6897
548 5IFS ADP 0.0005516 0.46543 21.519
549 1O3Y GTP 0.0001584 0.50532 22.8916
550 2J59 GTP 0.0002097 0.49935 22.8916
551 1J2J GTP 0.0002295 0.41431 22.8916
552 1RE0 GDP 0.00004755 0.5013 23.1707
553 1S9D GDP 0.00004129 0.50064 23.1707
554 3ZIA ATP 0.0001208 0.49375 23.1884
555 3ZIA ADP 0.0002006 0.48885 23.1884
556 4Q1A 2XZ 0.002745 0.51504 25.7143
557 4Q1A UDP 0.002745 0.51504 25.7143
558 3MJH GTP 0.00008091 0.5237 26.4706
559 1X1R GDP 0.0002665 0.49994 28.6517
560 5UWR GNP 0.00125 0.46662 29.6296
561 2ODE ALF GDP 0.0004497 0.49203 34.0426
562 2QN6 GDP 0.00002259 0.51477 50
Feedback