Receptor
PDB id Resolution Class Description Source Keywords
4RD0 1.71 Å NON-ENZYME: TRANSCRIPT_TRANSLATE STRUCTURE OF AIF2-GAMMA D19A VARIANT FROM SULFOLOBUS SOLFATA BOUND TO GDP SULFOLOBUS SOLFATARICUS ROSSMANN FOLD TRANSLATION
Ref.: IDENTIFICATION OF A SECOND GTP-BOUND MAGNESIUM ION ARCHAEAL INITIATION FACTOR 2. NUCLEIC ACIDS RES. V. 43 2946 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CL A:504;
Invalid;
none;
submit data
35.453 Cl [Cl-]
MG A:502;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
GDP A:503;
A:501;
Valid;
Valid;
none;
none;
Kd = 0.24 uM
443.201 C10 H15 N5 O11 P2 c1nc2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4RD0 1.71 Å NON-ENZYME: TRANSCRIPT_TRANSLATE STRUCTURE OF AIF2-GAMMA D19A VARIANT FROM SULFOLOBUS SOLFATA BOUND TO GDP SULFOLOBUS SOLFATARICUS ROSSMANN FOLD TRANSLATION
Ref.: IDENTIFICATION OF A SECOND GTP-BOUND MAGNESIUM ION ARCHAEAL INITIATION FACTOR 2. NUCLEIC ACIDS RES. V. 43 2946 2015
Members (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 257 families.
1 4RD6 Kd = 0.52 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 4RD2 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
3 4RD4 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
4 4RD1 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
5 4RCY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
6 4RD3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
7 4RCZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
8 4RD0 Kd = 0.24 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (11)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 222 families.
1 4RD6 Kd = 0.52 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 4RD2 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
3 4RD4 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
4 4RD1 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
5 4RCY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
6 4RD3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
7 4RCZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
8 4RD0 Kd = 0.24 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
9 1KK3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
10 1KK2 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
11 1KK1 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
50% Homology Family (11)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 185 families.
1 4RD6 Kd = 0.52 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 4RD2 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
3 4RD4 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
4 4RD1 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
5 4RCY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
6 4RD3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
7 4RCZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
8 4RD0 Kd = 0.24 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
9 1KK3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
10 1KK2 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
11 1KK1 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4RD0; Ligand: GDP; Similar sites found: 477
This union binding pocket(no: 1) in the query (biounit: 4rd0.bio1) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3IO3 ADP 0.01756 0.40339 1.43678
2 5I34 GDP 0.0000109 0.55224 1.44578
3 1AZT GSP 0.00000000009493 0.64029 1.49254
4 3EWA ANP 0.0001125 0.51045 1.5528
5 3R7F CP 0.01081 0.4256 1.64474
6 5GJC ATP 0.00001767 0.5496 1.68675
7 2XAU ADP 0.001437 0.44667 1.68675
8 5TSH ANP 0.00007409 0.4282 1.68675
9 3ZS9 ADP ALF 0.00002558 0.46568 1.69492
10 2WOJ ADP ALF 0.00003591 0.46076 1.69492
11 2XT3 ADP 0.000002518 0.62167 1.74419
12 1FNN ADP 0.001234 0.4366 1.79949
13 3ZQ6 ADP ALF 0.00001896 0.47009 1.85185
14 4XGU ADP 0.0001135 0.48676 1.92771
15 4A4Z ANP 0.001319 0.45837 1.92771
16 2XTZ GSP 0.00000000007164 0.6829 1.9774
17 3DC4 ADP 0.000001829 0.61626 2.03488
18 3DKP ADP 0.0005457 0.40119 2.04082
19 1JWY GDP 0.0000003273 0.60741 2.16867
20 1JWY ADP 0.000009014 0.55616 2.16867
21 4LYA ATP 0.00005435 0.51907 2.16867
22 4PX9 ADP 0.0003224 0.49441 2.16867
23 2VF7 ADP 0.000516 0.47262 2.16867
24 5XDR ADP 0.001487 0.45077 2.16867
25 1MLY ACZ PLP 0.003436 0.40175 2.16867
26 3FWY ADP 0.00001076 0.49062 2.2293
27 2QEN ADP 0.0000692 0.45995 2.28571
28 1F9V ADP 0.00001169 0.5814 2.30548
29 5KSZ GCP 0.0000005327 0.60595 2.40964
30 2JLR ANP 0.00006158 0.50421 2.40964
31 3TBK ANP 0.001089 0.47396 2.40964
32 1OYY AGS 0.001481 0.45592 2.40964
33 4PJ3 ANP 0.002539 0.4309 2.40964
34 2Y65 ADP 0.000001543 0.43775 2.46575
35 2ZR9 DTP 0.0001559 0.50354 2.5788
36 2WHX ADP 0.000008988 0.58791 2.6506
37 1DNP MHF 0.001596 0.47471 2.6506
38 2GK6 ADP 0.002934 0.45186 2.6506
39 2IXE ATP 0.0004885 0.44562 2.6506
40 3RC3 ANP 0.01041 0.41893 2.6506
41 5G41 AP5 0.003168 0.43905 2.69058
42 4RZ3 ADP 0.0003369 0.46579 2.71186
43 4V03 ADP 0.00005527 0.51236 2.72374
44 1ZCB GDP 0.00000003356 0.6278 2.76243
45 4P32 ADP 0.002706 0.41461 2.81124
46 1M7G ADX 0.0001309 0.4844 2.8436
47 1M7G ADP 0.0002324 0.47034 2.8436
48 1M7G AV2 0.000002085 0.46936 2.8436
49 2OFW ADX 0.0004771 0.46955 2.88462
50 2AWN ADP 0.000002182 0.63636 2.88714
51 4ZKD GDP 0.000000000004072 0.71166 2.89157
52 1YTM ATP 0.0002555 0.46173 2.89157
53 2FSH ANP 0.002782 0.44764 2.89157
54 1V8K ANP 0.0000009097 0.61233 2.92683
55 1EK0 GNP 0.00000000001318 0.70839 2.94118
56 3BFV ADP 0.00001436 0.55398 2.95203
57 3CX8 GSP 0.0000000001645 0.63258 2.95858
58 3B9Q MLI 0.00003759 0.56004 2.98013
59 4O48 ASP 0.02998 0.40103 3.01205
60 5N69 ADP 0.00001848 0.52793 3.01508
61 4XVU ATP 0.00009085 0.46765 3.04348
62 5MVR ADP 0.00001291 0.55624 3.08642
63 4IDN GNP 0.00007013 0.48076 3.13253
64 1X6V ADP 0.0004574 0.4087 3.13253
65 5J1J ANP 0.00003593 0.48356 3.15789
66 1XPJ TLA 0.02506 0.41509 3.1746
67 1NRJ GTP 0.00000000004877 0.74756 3.21101
68 4DKX GDP 0.00000000005899 0.81628 3.24074
69 2WKQ GTP 0.0000000004735 0.68037 3.31325
70 4AG5 ADP 0.00002807 0.56127 3.31633
71 4JLV ADP 0.0001328 0.51365 3.34572
72 1YQT ADP 0.00006092 0.5439 3.37349
73 4R43 GDP 0.0001283 0.50766 3.37349
74 5IRN ADP 0.00007433 0.5005 3.37349
75 1F5N GNP 0.000005705 0.49048 3.37349
76 5MZN ADP 0.001497 0.46686 3.37349
77 3G5S GSH 0.02135 0.40322 3.37349
78 1JJV ATP 0.00001792 0.5718 3.39806
79 3DEF GDP 0.000005732 0.551 3.43511
80 2PZE ATP 0.000004916 0.60967 3.49345
81 1R0X ATP 0.0001052 0.41342 3.4965
82 3EZ2 ADP 0.000292 0.49656 3.51759
83 3EC1 GDP 0.0000000007775 0.74931 3.52304
84 4M9Q GNP 0.00000000000205 0.79477 3.52423
85 2G77 GDP 0.0000000001902 0.7431 3.53535
86 2G77 AF3 0.0000002819 0.66711 3.53535
87 2Q2Y ADP 0.000337 0.47753 3.54223
88 2Q2Y MKR 0.0003305 0.47666 3.54223
89 1SVI GDP 0.0000000008774 0.77237 3.58974
90 5LB3 ADP 0.000206 0.50412 3.61446
91 5FTB ANP 0.00008423 0.50387 3.61446
92 5FHD ADP ALF 0.0002962 0.459 3.61446
93 2IS6 ADP 0.0001957 0.41237 3.61446
94 1Z06 GNP 0.000000000003341 0.74778 3.7037
95 3PCR GTP 0.00000000002676 0.73071 3.7037
96 2X77 GDP 0.00000000216 0.72822 3.7037
97 1HTW ADP 0.00002661 0.45338 3.79747
98 1QXA GLY GLY GLY 0.0375 0.40148 3.82979
99 5HCN GCP 0.000000005231 0.70996 3.83142
100 4LJ9 ACP 0.0008828 0.46687 3.83481
101 1JJ7 ADP 0.000002931 0.62732 3.84615
102 5I0H ADP BEF 0.0000003229 0.56914 3.85542
103 4UOX PUT 0.007023 0.41081 3.85542
104 2OG2 MLI 0.00003503 0.56917 3.89972
105 2Y8E GNP 0.00000000001264 0.70888 3.91061
106 1ZC3 GNP 0.000000000122 0.7344 4
107 1CS4 GSP 0.00000000007983 0.65512 4
108 3VX3 ADP 0.0008327 0.44402 4.03226
109 1UAD GNP 0.00000000005203 0.74688 4.0404
110 1Z6T ADP 0.0005284 0.45711 4.06091
111 1XKV ATP 0.0003649 0.47431 4.09639
112 4OHY ANP 0.00004524 0.47158 4.09639
113 1IHU AF3 0.0001191 0.47118 4.09639
114 1IHU ADP 0.0001166 0.46276 4.09639
115 1YZQ GNP 0.000000000004351 0.71057 4.11765
116 2EFE GNH 0.000000007034 0.68309 4.11985
117 1U8Z GDP 0.000000002681 0.64927 4.16667
118 3T34 GDP 0.000004573 0.52023 4.16667
119 4FCW ADP 0.0004681 0.4143 4.18006
120 3CNL GNP 0.0000000004415 0.78727 4.19847
121 3RLF ANP 0.0005188 0.43672 4.21053
122 2B8W ALF 5GP 0.000005472 0.53176 4.26829
123 4PPF FLC 0.000005644 0.59898 4.28571
124 3N5C GDP 0.0000000000222 0.83695 4.32099
125 2OBM ADP 0.0009898 0.48296 4.32277
126 3RWO GDP 0.00000000277 0.67372 4.32432
127 4ZG4 VO4 ADP 0.000001141 0.54385 4.33735
128 2FAH GDP 0.0001195 0.49115 4.33735
129 4OI4 ATP 0.0005566 0.43533 4.34783
130 2ZFI ADP 0.000004414 0.57893 4.37158
131 4KBF AMP 0.003262 0.44418 4.38356
132 3FVQ ATP 0.0004129 0.45286 4.45682
133 3AB3 GDP 0.00000002202 0.61709 4.47154
134 4BQS ADP 0.00006737 0.52129 4.54545
135 1KO8 6PG 0.001459 0.43344 4.57143
136 2DPY ADP 0.0004866 0.4919 4.57831
137 1TU3 GNP 0.000000000002081 0.80614 4.67836
138 1R2Q GNP 0.000000000005587 0.61807 4.70588
139 5K5Z ANP 0.0003047 0.44057 4.77707
140 1H65 GDP 0.00004623 0.4883 4.81482
141 1IWE IMP 0.00007719 0.54854 4.81928
142 5LTJ ADP 0.0002212 0.4901 4.81928
143 5LTJ BEF 0.004038 0.45217 4.81928
144 2BME GNP 0.000000000004619 0.79146 4.83871
145 5IRR GSP 0.0000000449 0.61387 4.87013
146 4FRZ ADP 0.000009526 0.42962 4.92228
147 3KTA AP5 0.0007311 0.45545 4.94506
148 1FZQ GDP 0.00000000002014 0.83901 4.97238
149 4NON GDP 0.00000003738 0.55924 5
150 1JI0 ATP 0.00004627 0.5443 5
151 2KIN ADP 0.0000006169 0.43332 5
152 3A1S GDP 0.0000001464 0.6412 5.03876
153 1X1R GDP 0.000000004706 0.60037 5.05618
154 1G6H ADP 0.0000062 0.60662 5.05837
155 1MKY GDP 0.000000000007808 0.85905 5.06024
156 2ZPA ADP 0.001367 0.43467 5.06024
157 1OXV ANP 0.00005086 0.42119 5.09915
158 1FP6 ADP 0.00004128 0.51209 5.19031
159 5L3W GDP 0.00001589 0.47349 5.22876
160 1TAD ALF 0.0000000005476 0.61558 5.24691
161 1TAD GDP 0.0000000005476 0.61558 5.24691
162 5KSP GDP 0.0000001838 0.6365 5.26316
163 2IYL GDP 0.000005723 0.57344 5.28169
164 4HSE ADP 0.0001458 0.4987 5.28967
165 5UQW GDP 0.0000000008919 0.65351 5.29101
166 4DSU GDP 0.000000001034 0.62451 5.29101
167 5KUT GDP 0.00000002326 0.55839 5.29101
168 5M04 GDP 0.00000000006514 0.82877 5.3012
169 3RAB GNP 0.000000000008458 0.78032 5.32544
170 4WOP CTP 0.000118 0.47601 5.33333
171 1RYH GNP 0.00000000008461 0.66014 5.41872
172 3Q72 GNP 0.00000000005124 0.61682 5.42169
173 1M7B GTP 0.0000000003212 0.71273 5.43478
174 2CBZ ATP 0.0000007008 0.66524 5.48523
175 3E70 GDP 0.000006105 0.5642 5.4878
176 4E3Q PMP 0.00801 0.42015 5.54217
177 3P4X ADP 0.0001459 0.41634 5.54217
178 3T12 GDP ALF 0.00000000003142 0.74536 5.55556
179 3T1O GDP 0.000000001607 0.72294 5.55556
180 4KAX GTP 0.000000000001608 0.79916 5.59006
181 1XTQ GDP 0.0000000001596 0.6985 5.64972
182 4H1V GNP 0.000002859 0.55772 5.69106
183 4YDS ATP 0.00003023 0.55378 5.70175
184 3NKV GNP 0.000000000009944 0.71216 5.71429
185 1I4D GDP 0.000000005646 0.73198 5.72917
186 2HF9 GSP 0.0000006618 0.53469 5.75221
187 3QF7 ANP 0.001521 0.43265 5.75342
188 2NGR GDP 0.000000001788 0.73212 5.75916
189 1GRN GDP 0.00000001059 0.66563 5.75916
190 1GRN AF3 0.0000002347 0.66198 5.75916
191 2NGR AF3 0.0000006198 0.64036 5.75916
192 4ITR GDP 0.0000001986 0.60138 5.75916
193 1R6B ADP 0.0002051 0.49166 5.78313
194 5M7P ADP 0.000835 0.44397 5.78313
195 1BG2 ADP 0.000000317 0.43927 5.78313
196 2ZJ5 ADP 0.03015 0.40237 5.78313
197 2X7I CIT 0.01965 0.40104 5.84416
198 2FFQ GSP 0.000000000004351 0.71078 5.84795
199 4QM7 GTP 0.0001042 0.51206 5.84795
200 3W5J GDP 0.00000007652 0.69894 5.88235
201 3SBD GNP 0.00000000007194 0.68152 5.88235
202 4R98 GNH 0.0000000255 0.68793 5.90406
203 1MH1 GNP 0.0000000001131 0.66025 5.91398
204 1SVK ALF GDP 0.0000000005808 0.60296 5.94901
205 1BO4 COA 0.01025 0.41491 5.95238
206 1G4U GDP 0.0000001715 0.60415 5.97826
207 1G4U AF3 0.0000124 0.5855 5.97826
208 2WIC GNP 0.0000000006755 0.75221 5.99251
209 5CK5 GDP 0.000000006483 0.56117 6.01266
210 1NVU GTP 0.00000000003055 0.76002 6.0241
211 2UZI GTP 0.00000000001733 0.70364 6.0241
212 1NVV GNP 0.00000000001356 0.69308 6.0241
213 1WQ1 AF3 0.0000001278 0.68968 6.0241
214 1WQ1 GDP 0.000000008961 0.62816 6.0241
215 1CLU DBG 0.000000003713 0.48649 6.0241
216 1TQ4 GDP 0.00000005961 0.61624 6.05327
217 2GDJ ANP 0.000132 0.50707 6.06061
218 4YC7 GNP 0.0000000004035 0.69915 6.07735
219 1FQK ALF 0.00000176 0.62914 6.12245
220 1FQK GDP 0.000000046 0.6007 6.12245
221 4WEI GLC GAL 0.00963 0.42797 6.13718
222 5JCZ GDP 0.00000000239 0.68477 6.14525
223 2OM2 GDP 0.00000008672 0.60931 6.15385
224 4LPS GDP 0.00000003788 0.6691 6.19835
225 3NHB ADP 0.00003368 0.5578 6.20915
226 4LX0 BEF GDP 0.000000000005832 0.79065 6.21469
227 3COB ADP 0.0000008662 0.44751 6.23306
228 1HE1 GDP 0.00000008112 0.61054 6.25
229 1HE1 AF3 0.000006753 0.58716 6.25
230 1A4R GNH 0.0000000003623 0.73068 6.28272
231 1A4R GDP 0.0000000003453 0.72126 6.28272
232 1G3Q ADP 0.00003495 0.52819 6.32911
233 5IFS ADP 0.0002758 0.42368 6.32911
234 1BH2 GSP 0.0000000009216 0.6082 6.34921
235 4C4P GNP 0.00000000002846 0.68236 6.35838
236 2ODE ALF GDP 0.0000000002949 0.62376 6.38298
237 1Y3A GDP 0.0000001292 0.58238 6.38298
238 1APZ ASP 0.02254 0.40623 6.38298
239 2GJ8 ALF GDP 0.00000000004254 0.67419 6.39535
240 2HV8 GTP 0.0000000001385 0.67163 6.39535
241 2XTN GTP 0.000002834 0.52889 6.41026
242 1VHT BA3 0.0003819 0.47339 6.42202
243 3WUR O4B 0.02576 0.40536 6.43275
244 2QZ4 ADP 0.0001789 0.48868 6.48855
245 1SQ5 ADP 0.00004145 0.52467 6.49351
246 5L3R GCP 0.000001403 0.53092 6.50602
247 4TTQ ATP 0.00006992 0.43656 6.51163
248 2D7C GTP 0.00000000008717 0.73739 6.58683
249 1D2N ANP 0.002056 0.42319 6.61765
250 3PQC GDP 0.00000008906 0.642 6.66667
251 4QRH 0O2 0.003841 0.40269 6.66667
252 3KJI ADP 0.00592 0.42076 6.69291
253 3REF GDP 0.000000001929 0.67084 6.70103
254 4GOX A3P 0.001598 0.41757 6.70927
255 2C04 GCP 0.00007042 0.49596 6.73401
256 2A5F GTP 0.000000000004027 0.74473 6.73575
257 3E5H GNP 0.00000000009478 0.67719 6.74157
258 5GOE GDP 0.0000000002453 0.76084 6.74699
259 2FJU GSP 0.00000000003911 0.75163 6.74699
260 5JCP GDP ALF 0.0000000003419 0.7318 6.74699
261 3BC1 GNP 0.00000000002268 0.76217 6.77966
262 1D5C GDP 0.00000000233 0.69481 6.79012
263 4E03 ADP 0.0000515 0.44713 6.79612
264 3ZFD ANP 0.00000006671 0.64783 6.83761
265 5BQ5 ADP BEF 0.0003875 0.4731 6.87831
266 1ZD9 GDP 0.00000002712 0.63894 6.91489
267 2A5J GDP 0.0000000007073 0.73949 6.98795
268 2ZEJ GDP 0.0000001444 0.54637 7.06522
269 4D81 ADP 0.0005808 0.45999 7.06714
270 1PUJ GNP 0.000000000087 0.76964 7.0922
271 1P4V GLY 0.02667 0.40262 7.11864
272 4GDX GLU 0.008535 0.43452 7.21925
273 4DCT GDP 0.0000000001046 0.7907 7.22892
274 2J59 GTP 0.000000000005896 0.75657 7.22892
275 1O3Y GTP 0.00000000000747 0.75265 7.22892
276 4YS0 ADP 0.001142 0.44224 7.22892
277 1KSH GDP 0.000000000001675 0.78395 7.23684
278 3T5G GDP 0.000000001044 0.73165 7.23684
279 1Z0K GTP 0.000000000004702 0.76057 7.24638
280 2FNA ADP 0.0003441 0.45197 7.28291
281 1S9D GDP 0.0000000001769 0.77986 7.31707
282 1RE0 GDP 0.00000000001285 0.63592 7.31707
283 5TB5 GDP 0.0000000009011 0.7346 7.33333
284 4K81 GTP 0.00000000004713 0.65993 7.36434
285 1E96 GTP 0.0000000001743 0.66788 7.38916
286 3KUD GDP 0.000000002651 0.67375 7.40741
287 5TAR GDP 0.000000002374 0.70449 7.43243
288 2WJG GDP 0.0000000002206 0.78839 7.44681
289 2GCO GNP 0.0000000002538 0.67105 7.46269
290 2GCN GDP 0.00000002142 0.62726 7.46269
291 4YMU ATP 0.00008426 0.52352 7.5
292 5X40 ACP 0.001204 0.43118 7.53425
293 4BAS GNP 0.00000000007612 0.72934 7.53769
294 4HI0 GDP 0.0000003593 0.58305 7.53769
295 5H67 ATP 0.009776 0.41181 7.53769
296 2J0V GDP 0.00000001505 0.68816 7.54717
297 4KFU ACP 0.000008848 0.43352 7.54717
298 3QKT ANP 0.001215 0.41549 7.66962
299 3M1I GTP 0.00000000001098 0.69634 7.76256
300 3WYF GTP 0.00000000001911 0.67421 7.76256
301 3BFX A3P 0.003314 0.41794 7.77027
302 1OW3 GDP 0.000000008254 0.61218 7.77202
303 1NF3 GNP 0.0000000002957 0.65932 7.8125
304 4IOK XPO 0.004158 0.43898 7.8712
305 4IOK ADP 0.005235 0.43898 7.8712
306 1UKZ ADP 0.003042 0.42772 7.88177
307 1M2O GNP 0.0000000001069 0.67618 7.89474
308 2W58 ADP 0.000003504 0.62385 7.92079
309 5VGR GDP 0.0004948 0.45838 7.95181
310 2VB6 ADP BEF 0.00003407 0.4845 8.05369
311 2OZE AGS 0.01635 0.40479 8.05369
312 1F6B GDP 0.0000000005788 0.61889 8.08081
313 4D0N GDP 0.000000003802 0.57385 8.10811
314 3AQ4 GDP 0.00000000007544 0.79746 8.15217
315 1KMQ GNP 0.00000000009727 0.72854 8.15217
316 1Y63 ADP 0.00001849 0.54864 8.15217
317 4PFO ADP 0.0000559 0.49126 8.19277
318 5H56 TYD 0.001413 0.43811 8.20513
319 5H56 ADP 0.001413 0.43811 8.20513
320 4XOI GTP 0.0000000002523 0.67596 8.33333
321 3LXR GDP 0.00000002526 0.66741 8.33333
322 4XSH GSP 0.0000000004214 0.7175 8.37989
323 2WJH GDP 0.0000000002425 0.63268 8.43373
324 2WJH FLC 0.0000004325 0.5299 8.43373
325 1OS1 PYR 0.001297 0.43972 8.43373
326 1OS1 ATP 0.001285 0.43838 8.43373
327 1TX4 ALF GDP 0.0000000001098 0.70586 8.47458
328 1Z0J GTP 0.000000000006852 0.70385 8.47458
329 1LVG ADP 0.000001608 0.61913 8.58586
330 3Q85 GNP 0.00000000001266 0.651 8.87574
331 4V0K GDP 0.00000002105 0.6004 8.87574
332 4CVN ADP 0.00001911 0.56399 8.90052
333 1XX6 ADP 0.0001166 0.5309 8.90052
334 1L2T ATP 0.0007716 0.42263 8.93617
335 2EW1 GNP 0.000000000003641 0.78835 8.95522
336 4WZ6 ATP 0.00001312 0.58 8.96552
337 2A9K GDP 0.00000001077 0.6653 8.96861
338 2QTV GNP 0.0000000002318 0.67856 8.98204
339 5HR5 ADP 0.000523 0.45731 9.15663
340 5DI3 GNP 0.00000000000774 0.77072 9.18919
341 1GWN GTP 0.0000000003686 0.68977 9.26829
342 3WYG GTP 0.00000000002105 0.67319 9.34066
343 5KDO GDP 0.0000001338 0.6013 9.45946
344 3B5J 12D 0.00006411 0.53704 9.46502
345 5O2T GSP 0.00000000001343 0.69361 9.46746
346 3GJ0 GDP 0.0000000003186 0.78061 9.50226
347 3Q9L ATP 0.00004732 0.50363 9.61539
348 3H4S ADP 0.00000204 0.62833 9.62963
349 5IRC GDP 0.00000001504 0.57824 9.67742
350 4MKF AP5 0.002436 0.44017 9.67742
351 3TK1 GDP 0.00000000008063 0.83962 9.69697
352 3GJX GTP 0.00000000001822 0.76958 9.72222
353 1IBR GNP 0.00000000001911 0.68853 9.72222
354 5BXQ GDP 0.00000000021 0.63347 9.72222
355 4U00 ADP 0.00001077 0.40255 9.83607
356 5EE5 GTP 0.000000000003858 0.78332 9.94152
357 1NJF AGS 0.0003527 0.45152 10
358 1NJF ADP 0.000389 0.43776 10
359 5L3V GDP 0.000002052 0.57876 10.0334
360 4LC1 GDP 0.000000001249 0.75172 10.089
361 1KAO GDP 0.00000001072 0.66538 10.1796
362 1B7T ADP 0.00004001 0.51888 10.2564
363 1ION ADP 0.00009345 0.50177 10.2881
364 2W83 GTP 0.000000000003405 0.76601 10.3896
365 1KK8 BEF ADP 0.00001132 0.53119 10.3896
366 4GOJ GNP 0.000000000001051 0.80686 10.4167
367 3LRE ADP 0.000001651 0.63448 10.4225
368 1ZJ6 G3D 0.00000000004292 0.8091 10.6024
369 1YZG GDP 0.00000000005193 0.80516 10.6145
370 1WA5 GTP 0.00000000001827 0.63633 10.7955
371 3DOE GTP 0.000000000002233 0.77326 10.9091
372 1GOT GDP 0.0000002253 0.58467 10.9589
373 4YLG GDP 0.0000000007696 0.71616 10.9827
374 1MR3 G3D 0.0000000003401 0.62529 11.0497
375 4U5X GNP 0.0000000007401 0.66503 11.236
376 1S8F GDP 0.0000000006743 0.62081 11.2994
377 1WDT GTP 0.0000000004299 0.71713 11.3253
378 5HPY GDP 0.000000007483 0.61368 11.3514
379 1GOJ ADP 0.0000003743 0.67359 11.5493
380 1CXZ GSP 0.00000000003301 0.74447 11.6279
381 5E5U MLI 0.008251 0.41789 11.7424
382 1R4A GNP 0.000000000007742 0.73316 11.7647
383 2RCN GDP 0.0000000002005 0.79041 12.0112
384 4ZI2 GNP 0.0000000000007796 0.81227 12.0301
385 4ZNL BEF ADP 0.0001053 0.50542 12.0438
386 2V7Q ATP 0.00003521 0.52145 12.5
387 1W0J ADP 0.00004988 0.50837 12.5
388 2V7Q ADP 0.0001276 0.50778 12.5
389 1W0J ADP BEF 0.0006549 0.44855 12.5
390 2CK3 ANP 0.0006987 0.44733 12.5
391 2CK3 ADP 0.001054 0.42457 12.5
392 5AHO TLA 0.01873 0.41617 12.5
393 1OIX GDP 0.00000000008257 0.73838 12.5654
394 1OIV GDP 0.00000001021 0.6497 12.5654
395 3B7G ANP 0.001292 0.45367 12.6087
396 5GVR LMR 0.001568 0.45303 12.8205
397 1G16 GDP 0.00000005753 0.60938 12.9412
398 5L3S GNP 0.000005983 0.50594 13.1757
399 5L3S G 0.01241 0.4244 13.1757
400 3QBT GNP 0.000000000002449 0.73503 13.2184
401 3TNF GNP 0.000000000006743 0.68845 13.2184
402 4LHW GNP 0.0000000001165 0.67377 13.2184
403 1J2J GTP 0.00000000001103 0.74555 13.3333
404 1YRB GDP 0.0000000011 0.71965 13.3588
405 4XTR ADP 0.0001204 0.48051 13.5135
406 4XTR ATP 0.00007423 0.47109 13.5135
407 1WF3 GNP 0.0000000001111 0.65924 13.6213
408 4D0G GTP 0.0000000001426 0.71798 13.7143
409 4R2I ANP 0.003175 0.45009 13.8095
410 1VG8 GNP 0.000000000002907 0.80353 14.0097
411 1VG0 GDP 0.000000001977 0.7081 14.0097
412 2BCG GDP 0.000000009463 0.6588 14.0777
413 3A4M ADP 0.000009265 0.43912 14.6154
414 2PL3 ADP 0.0003576 0.49216 14.8305
415 2VVG ADP 0.000000503 0.66593 14.8571
416 3UIE ANP 0.00006421 0.50934 15
417 5E95 GDP 0.00000001569 0.65805 15.4639
418 1GP2 GDP 0.0000002322 0.572 15.493
419 1DS6 GDP 0.000000004495 0.57249 15.625
420 4TMZ GSP 0.0000000000009323 0.78865 15.6522
421 1VG9 GDP 0.0000000003416 0.76628 15.6757
422 1YZN GNP 0.000000000009896 0.69848 15.6757
423 1VG1 GDP 0.000000000117 0.63614 15.6757
424 1Z08 GNP 0.000000007773 0.63137 15.8824
425 3ZIA ADP 0.000111 0.44545 15.942
426 3ZIA ATP 0.00005594 0.44138 15.942
427 1T5C ADP 0.0000008667 0.43024 16.0458
428 2F9L GDP 0.00000001595 0.61862 16.0804
429 5UFQ GNP 0.0000000004382 0.6504 16.3934
430 1KY3 GDP 0.000000004431 0.61001 16.4835
431 4NTX AMR 0.02476 0.40222 16.6667
432 2W2X GSP 0.00000000003119 0.75582 16.7568
433 5J1S ATP 0.0006299 0.4274 17.0732
434 1YVD GNP 0.000000000005823 0.72237 17.1598
435 3H86 AP5 0.0007487 0.45575 17.1875
436 3IIJ ADP 0.00003218 0.53692 17.2222
437 1Z0A GDP 0.0000000003715 0.75247 17.2414
438 2FH5 GTP 0.00000000001601 0.76813 17.2897
439 1UPT GTP 0.00000000001653 0.75699 18.3333
440 2CJW GDP 0.00000000007809 0.81035 18.75
441 2C5L GTP 0.000000000006232 0.70487 18.8034
442 1Z0F GDP 0.0000000001226 0.78744 18.9944
443 1FQJ ALF 0.0000005157 0.65181 19.0476
444 1FQJ GDP 0.00000002742 0.60925 19.0476
445 3CPJ GDP 0.000000008721 0.60003 19.2825
446 2HT6 GDP 0.000000000006354 0.87926 20.6897
447 1LFD GNP 0.000000000007473 0.71749 22.9885
448 4DID GDP 0.00000002004 0.68224 23.0263
449 3TKL GTP 0.000000000003848 0.74497 23.4694
450 3WXM GTP 0.0000000000002444 0.84556 23.8554
451 3VMF GTP 0.0000000000000866 0.78963 23.8554
452 5SZH GNP 0.000000000003186 0.80184 25.1232
453 3SFV GDP 0.00000002982 0.61093 25.4144
454 3MJH GTP 0.000000000001 0.74893 26.4706
455 5WDR GNP 0.00000000002083 0.6867 28.0702
456 5XCO GDP 0.000000002133 0.62154 28.5714
457 4J0Q GDP 0.000000000001243 0.91465 28.6747
458 3DDC GNP 0.00000000001989 0.68749 30.1205
459 2VOH CIT 0.005219 0.44218 30.7692
460 2C78 GNP 0.00000000000002442 0.87492 32.0988
461 2C77 GNP 0.00000000000002109 0.86112 32.0988
462 3WY9 GDP 0.000000000001506 0.91049 34.6988
463 3WYA GDP 0.000000000002333 0.8846 34.6988
464 3U6B GDP 0.0000000000001503 0.96047 35.7868
465 5JBQ GDP 0.0000000000004782 0.91812 35.7868
466 4G5G GDP 0.0000000000006686 0.91103 35.7868
467 3U6K GDP 0.000000000001144 0.89968 35.7868
468 4PC3 GDP 0.0000000001551 0.75825 35.7868
469 4P3Y GDP 0.0000000000001902 0.68709 35.7868
470 2BVN GNP 0.0000000000000232 0.93184 35.8779
471 1D8T GDP 0.0000000000004526 0.69686 35.8779
472 4HDQ GNP 0.00000000009538 0.73895 41.3174
473 4HDO GNP 0.00000000001927 0.68794 41.3174
474 1GUA GNP 0.00000000001259 0.69392 41.9162
475 3X1Z GNP 0.00000000001592 0.67631 41.9162
476 4KVG GTP 0.0000000000232 0.69937 42.2619
477 1Z2A GDP 0.00000003305 0.60558 43.4524
Pocket No.: 2; Query (leader) PDB : 4RD0; Ligand: GDP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4rd0.bio1) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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