Receptor
PDB id Resolution Class Description Source Keywords
4RZB 1.86 Å EC: 3.-.-.- THE STRUCTURE OF N-FORMIMINO-L-GLUTAMATE IMINOHYDROLASE FROM PSEUDOMONAS AERUGINOSA COMPLEXED WITH N-FORMIMINO-L-ASPARTAW ITH MERCURY PSEUDOMONAS AERUGINOSA PAO1 AMIDOHYDROLASE FOLD N-FORMIMINO-L-GLUTAMATE IMINOHYDROLASEFORMIMINO-L-ASPARTATE HYDROLASE
Ref.: STRUCTURE OF N-FORMIMINO-L-GLUTAMATE IMINOHYDROLASE PSEUDOMONAS AERUGINOSA. BIOCHEMISTRY V. 54 890 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SO4 B:507;
A:506;
B:508;
B:506;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
ZN A:502;
B:502;
Part of Protein;
Part of Protein;
none;
none;
submit data
65.409 Zn [Zn+2...
NFQ A:501;
B:501;
Valid;
Valid;
none;
none;
Ki = 30 uM
160.128 C5 H8 N2 O4 [H]/N...
GOL A:507;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4RZB 1.86 Å EC: 3.-.-.- THE STRUCTURE OF N-FORMIMINO-L-GLUTAMATE IMINOHYDROLASE FROM PSEUDOMONAS AERUGINOSA COMPLEXED WITH N-FORMIMINO-L-ASPARTAW ITH MERCURY PSEUDOMONAS AERUGINOSA PAO1 AMIDOHYDROLASE FOLD N-FORMIMINO-L-GLUTAMATE IMINOHYDROLASEFORMIMINO-L-ASPARTATE HYDROLASE
Ref.: STRUCTURE OF N-FORMIMINO-L-GLUTAMATE IMINOHYDROLASE PSEUDOMONAS AERUGINOSA. BIOCHEMISTRY V. 54 890 2015
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 253 families.
1 4RZB Ki = 30 uM NFQ C5 H8 N2 O4 [H]/N=C/N[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 4RZB Ki = 30 uM NFQ C5 H8 N2 O4 [H]/N=C/N[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 173 families.
1 4RZB Ki = 30 uM NFQ C5 H8 N2 O4 [H]/N=C/N[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: NFQ; Similar ligands found: 5
No: Ligand ECFP6 Tc MDL keys Tc
1 NFQ 1 1
2 NIG 0.527778 0.870968
3 OEM 0.46875 0.69697
4 NCD 0.428571 0.777778
5 EKQ 0.428571 0.65
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4RZB; Ligand: NFQ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4rzb.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 4RZB; Ligand: NFQ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4rzb.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
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