Receptor
PDB id Resolution Class Description Source Keywords
4TMZ 2.28 Å NON-ENZYME: OTHER TRANSLATION INITIATION FACTOR EIF5B (517-858) FROM C. THERMO BOUND TO GTPGAMMAS AND POTASSIUM CHAETOMIUM THERMOPHILUM TRANSLATION TRANSLATION FACTOR GTPASE
Ref.: A MONOVALENT CATION ACTS AS STRUCTURAL AND CATALYTI COFACTOR IN TRANSLATIONAL GTPASES. EMBO J. V. 33 2547 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
K A:903;
B:903;
Part of Protein;
Part of Protein;
none;
none;
submit data
39.098 K [K+]
CL B:906;
B:905;
Invalid;
Invalid;
none;
none;
submit data
35.453 Cl [Cl-]
MG A:902;
B:902;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
GOL B:904;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
GSP B:901;
A:901;
Valid;
Valid;
none;
none;
Kd = 0.92 uM
539.246 C10 H16 N5 O13 P3 S c1nc2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4TMZ 2.28 Å NON-ENZYME: OTHER TRANSLATION INITIATION FACTOR EIF5B (517-858) FROM C. THERMO BOUND TO GTPGAMMAS AND POTASSIUM CHAETOMIUM THERMOPHILUM TRANSLATION TRANSLATION FACTOR GTPASE
Ref.: A MONOVALENT CATION ACTS AS STRUCTURAL AND CATALYTI COFACTOR IN TRANSLATIONAL GTPASES. EMBO J. V. 33 2547 2014
Members (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 4TMX - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
2 4TMZ Kd = 0.92 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
3 4TMV - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
4 4TMT - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
5 4TMW Kd = 4.1 uM GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
70% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 222 families.
1 4NCN - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
2 4NCL - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 4TMX - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
4 4TMZ Kd = 0.92 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
5 4TMV - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
6 4TMT - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
7 4TMW Kd = 4.1 uM GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 185 families.
1 4NCN - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
2 4NCL - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 4TMX - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
4 4TMZ Kd = 0.92 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
5 4TMV - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
6 4TMT - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
7 4TMW Kd = 4.1 uM GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GSP; Similar ligands found: 132
No: Ligand ECFP6 Tc MDL keys Tc
1 GSP 1 1
2 GP3 0.897436 0.925
3 GTP 0.853659 0.948718
4 GNH 0.829268 0.936709
5 GDP 0.817073 0.948718
6 G1R 0.8 0.936709
7 GCP 0.77907 0.925
8 GNP 0.770115 0.925
9 GMV 0.767442 0.925
10 5GP 0.756098 0.935897
11 G 0.756098 0.935897
12 G2R 0.747253 0.91358
13 GKE 0.744681 0.91358
14 GDD 0.744681 0.91358
15 GDC 0.744681 0.91358
16 GPG 0.73913 0.91358
17 GTG 0.736842 0.891566
18 G3A 0.729167 0.925
19 G5P 0.721649 0.925
20 GDR 0.71875 0.91358
21 GFB 0.71875 0.91358
22 GAV 0.714286 0.987179
23 GP2 0.712644 0.91358
24 6CK 0.71134 0.891566
25 Y9Z 0.708333 0.860465
26 JB2 0.69697 0.91358
27 GKD 0.69697 0.91358
28 GDP MG 0.696629 0.878049
29 G2P 0.692308 0.91358
30 GDX 0.69 0.925
31 GPD 0.69 0.880952
32 GDP BEF 0.688889 0.857143
33 GCP G 0.677419 0.888889
34 ALF 5GP 0.67033 0.847059
35 0O2 0.666667 0.935897
36 GTP MG 0.666667 0.878049
37 BEF GDP 0.666667 0.847059
38 YGP 0.663265 0.858824
39 JB3 0.657143 0.902439
40 GDP ALF 0.645833 0.847059
41 GDP AF3 0.645833 0.847059
42 G G 0.642857 0.888889
43 GMP 0.641975 0.835443
44 G3D 0.638298 0.935897
45 NGD 0.635514 0.91358
46 2MD 0.633027 0.894118
47 CAG 0.630631 0.840909
48 G4P 0.625 0.935897
49 U2G 0.62037 0.891566
50 FEG 0.62037 0.83908
51 MGD 0.616071 0.894118
52 ZGP 0.614679 0.872093
53 CG2 0.609091 0.891566
54 TPG 0.598291 0.804348
55 3GP 0.595506 0.898734
56 GDP 7MG 0.590476 0.86747
57 GH3 0.581633 0.924051
58 MD1 0.581197 0.894118
59 PGD 0.581197 0.926829
60 2GP 0.577778 0.911392
61 DGT 0.561224 0.878049
62 DBG 0.558333 0.902439
63 G1G 0.550847 0.880952
64 SAP 0.547368 0.924051
65 AGS 0.547368 0.924051
66 FE9 0.546219 0.8
67 G4M 0.539062 0.840909
68 U A G G 0.538462 0.888889
69 G A A A 0.529915 0.878049
70 MGP 0.525253 0.91358
71 GPX 0.524272 0.898734
72 BGO 0.521739 0.879518
73 DGI 0.520408 0.878049
74 6G0 0.52 0.91358
75 I2C FE2 CMO CMO 0.516667 0.774194
76 IDP 0.515464 0.923077
77 GGM 0.508475 0.858824
78 G1R G1R 0.508065 0.879518
79 PGD O 0.504 0.875
80 G G U 0.5 0.888889
81 GTA 0.486726 0.891566
82 P2G 0.484536 0.839506
83 GPC 0.483607 0.83908
84 G C 0.483333 0.857143
85 P1G 0.474747 0.829268
86 DG 0.474227 0.865854
87 DGP 0.474227 0.865854
88 BA3 0.46875 0.85
89 AP5 0.463918 0.85
90 B4P 0.463918 0.85
91 IMP 0.463918 0.910256
92 G2Q 0.462963 0.91358
93 G G G RPC 0.459016 0.833333
94 APC G U 0.456 0.843373
95 U G A 0.452555 0.847059
96 ATP 0.45 0.873418
97 G G G C 0.448819 0.869048
98 A2D 0.447917 0.85
99 5FA 0.445545 0.873418
100 AQP 0.445545 0.873418
101 A G C C 0.445312 0.86747
102 G7M 0.444444 0.901235
103 G U34 0.442623 0.847059
104 01G 0.442478 0.860465
105 ITT 0.44 0.825
106 SGP 0.44 0.876543
107 G C C C 0.431818 0.879518
108 AN2 0.43 0.8625
109 DG DG 0.428571 0.825581
110 A4P 0.42623 0.829545
111 UCG 0.424242 0.86747
112 C2E 0.423077 0.875
113 PCG 0.423077 0.886076
114 35G 0.423077 0.886076
115 MGO 0.420561 0.823529
116 ADP 0.42 0.873418
117 ANP 0.419048 0.851852
118 5GP 5GP 0.419048 0.839506
119 ADQ 0.418182 0.829268
120 APR 0.417476 0.85
121 AR6 0.417476 0.85
122 7DT 0.417476 0.860759
123 A G U 0.414286 0.847059
124 AD9 0.413462 0.851852
125 UP5 0.413223 0.831325
126 A22 0.412844 0.8625
127 25L 0.412281 0.8625
128 M33 0.411765 0.839506
129 JBT 0.410405 0.783505
130 ACP 0.407767 0.851852
131 ACQ 0.40566 0.851852
132 A1R 0.405405 0.8
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4TMZ; Ligand: GSP; Similar sites found: 424
This union binding pocket(no: 1) in the query (biounit: 4tmz.bio2) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3P4X ADP 0.0002442 0.402 1.15942
2 5MZN ADP 0.0009869 0.47806 1.44928
3 3FWY ADP 0.0000708 0.45264 1.44928
4 1SFF IK2 0.007368 0.40126 1.44928
5 1G6O ADP 0.0002955 0.48061 1.51515
6 3H86 AP5 0.002026 0.43329 1.5625
7 5L3W GDP 0.00004618 0.45027 1.63399
8 1JI0 ATP 0.0001653 0.51806 1.66667
9 1GOJ ADP 0.000001857 0.63403 1.73913
10 3MD0 GDP 0.000000004197 0.54855 1.73913
11 3ZFD ANP 0.0000005269 0.51609 1.73913
12 4IDN GNP 0.00002312 0.50316 1.73913
13 2C04 GCP 0.00008072 0.49551 1.73913
14 5LB3 ADP 0.000344 0.49503 1.73913
15 1V8K ANP 0.000004873 0.46843 1.73913
16 1ION ADP 0.0002106 0.42532 1.73913
17 3VM7 GLC 0.01463 0.41817 1.73913
18 4LC1 GDP 0.00000001689 0.69973 1.78042
19 4ZNL BEF ADP 0.00007446 0.51477 1.82482
20 3NHB ADP 0.00009457 0.53701 1.96078
21 5L3V GDP 0.000009959 0.54932 2.00669
22 5L3S GNP 0.00001064 0.50286 2.01342
23 5L3S G 0.03423 0.40121 2.01342
24 2RCN GDP 0.0000000002907 0.59581 2.02899
25 1YTM ATP 0.0003887 0.45599 2.02899
26 2WOJ ADP ALF 0.00009351 0.45201 2.02899
27 3DZD ADP 0.001077 0.40229 2.02899
28 3QXC ATP 0.001077 0.43481 2.06612
29 2CJW GDP 0.0000000001754 0.60087 2.08333
30 2IYL GDP 0.00003918 0.43989 2.11268
31 4D81 ADP 0.0009678 0.45184 2.12014
32 3DEF GDP 0.00001445 0.47547 2.29008
33 2HT6 GDP 0.00000000003779 0.60451 2.29885
34 1ZIN AP5 0.007734 0.41363 2.30415
35 4P4T GDP 0.00000385 0.54796 2.31884
36 4H1V GNP 0.000008001 0.54031 2.31884
37 3QF7 ANP 0.004688 0.41377 2.31884
38 1G41 ADP 0.0003855 0.41323 2.31884
39 5HR5 ADP 0.0008384 0.41296 2.31884
40 1R6B ADP 0.0003185 0.41105 2.31884
41 1ZUI SKM 0.0006217 0.45676 2.38095
42 3E70 GDP 0.0000186 0.4606 2.43902
43 1OFH ADP 0.0002221 0.42149 2.58065
44 1H65 GDP 0.0001276 0.46243 2.59259
45 2ZFI ADP 0.00007847 0.52025 2.6087
46 3BFV ADP 0.00008799 0.51782 2.6087
47 2QG6 NMN 0.001663 0.42851 2.6087
48 2Y65 ADP 0.000004101 0.42312 2.6087
49 4FRZ ADP 0.00001763 0.41549 2.6087
50 2ZR9 DTP 0.0001797 0.41024 2.6087
51 5X40 ACP 0.002593 0.41384 2.73973
52 1UJ2 C5P 0.0008869 0.43833 2.77778
53 1UJ2 ADP 0.003403 0.41391 2.77778
54 4GOX A3P 0.002316 0.41586 2.8754
55 2OFW ADX 0.001556 0.44312 2.88462
56 1TQ4 GDP 0.0000002658 0.59141 2.89855
57 1W0J ADP 0.00006243 0.4484 2.89855
58 1W0J ADP BEF 0.001854 0.40501 2.89855
59 1BG2 ADP 0.0000008012 0.4255 3.07692
60 5I34 GDP 0.00003255 0.53193 3.18841
61 1IWE IMP 0.0001932 0.52453 3.18841
62 1FNN ADP 0.001071 0.44118 3.18841
63 1Z6T ADP 0.001511 0.43871 3.18841
64 4YS0 ADP 0.002127 0.43208 3.18841
65 2VVG ADP 0.000003383 0.41252 3.18841
66 4HSE ADP 0.0003494 0.40442 3.18841
67 2VF7 ADP 0.000448 0.40058 3.18841
68 1VHT BA3 0.0006014 0.40641 3.21101
69 1P72 ADP 0.009033 0.40285 3.29341
70 1MR3 G3D 0.000000005216 0.57311 3.31492
71 2PEZ DAT 0.002367 0.42778 3.35196
72 3ZQ6 ADP ALF 0.00004607 0.492 3.39506
73 4QOS ADP 0.001352 0.44978 3.39623
74 2RC8 DSN 0.0299 0.40309 3.40136
75 2V7Q ATP 0.0000469 0.4451 3.42466
76 2CK3 ANP 0.001635 0.43315 3.42466
77 2CK3 ADP 0.001853 0.41985 3.42466
78 2V7Q ADP 0.0002991 0.40082 3.42466
79 4RLQ 3SK 0.01974 0.41081 3.46821
80 1QF5 GDP 0.0001563 0.49838 3.47826
81 1QF5 RPL 0.008911 0.44649 3.47826
82 2C9O ADP 0.0007223 0.44448 3.47826
83 3ZH4 FLC 0.03174 0.40563 3.47826
84 2ZE7 DST 0.005694 0.40455 3.47826
85 2ZE7 AMP 0.005321 0.40425 3.47826
86 3DC4 ADP 0.00001289 0.4345 3.48837
87 2XT3 ADP 0.000006034 0.41857 3.48837
88 1LVG ADP 0.00001135 0.42996 3.53535
89 3CX8 GSP 0.0000000006286 0.70102 3.5503
90 4WOP CTP 0.0002475 0.46438 3.55556
91 1SQ5 ADP 0.0004291 0.47842 3.57143
92 1O3Y GTP 0.00000000007159 0.72453 3.61446
93 3AB3 GDP 0.0000001182 0.57535 3.65854
94 3TMK T5A 0.003459 0.41661 3.7037
95 3FYH ADP 0.003712 0.40913 3.72671
96 4PX9 ADP 0.0004268 0.49032 3.76712
97 1SVK ALF GDP 0.000000002376 0.67928 3.76812
98 1F5N GNP 0.000001694 0.51565 3.76812
99 4WZ6 ATP 0.00003994 0.55705 3.7931
100 3QKT ANP 0.003274 0.41139 3.83481
101 3KJI ADP 0.0003018 0.42477 3.93701
102 1UKZ ADP 0.009836 0.40247 3.94089
103 1Y3A GDP 0.000001153 0.55163 3.95137
104 2B8W ALF 5GP 0.000001371 0.55105 3.96341
105 1FQK ALF 0.0000008935 0.64939 4
106 1FQK GDP 0.0000003222 0.57438 4
107 1NJF AGS 0.0008326 0.42888 4
108 1NJF ADP 0.001123 0.41275 4
109 1JWY GDP 0.00000104 0.51484 4.05797
110 1JWY ADP 0.00005892 0.43211 4.05797
111 3COB ADP 0.000004062 0.42565 4.05797
112 1QF9 C5P 0.004648 0.42007 4.12371
113 1BH2 GSP 0.000000002184 0.6782 4.12698
114 1NN5 ANP 0.002601 0.42468 4.18605
115 3Q72 GNP 0.00000000003952 0.60405 4.21687
116 1L2T ATP 0.002007 0.41193 4.25532
117 2XTN GTP 0.000002794 0.53583 4.2735
118 3R7F CP 0.01259 0.42245 4.27632
119 1YZN GNP 0.00000000001152 0.70606 4.32432
120 4R43 GDP 0.0007168 0.47322 4.34783
121 2Q2Y ADP 0.001244 0.44853 4.34783
122 2Q2Y MKR 0.001324 0.44618 4.34783
123 4U5X GNP 0.0000000002565 0.66717 4.49438
124 3TK1 GDP 0.000000006757 0.53356 4.54545
125 1YRB GDP 0.000000000925 0.61898 4.58015
126 3W9F I3P 0.01734 0.41164 4.61538
127 4AG5 ADP 0.00008555 0.53719 4.63768
128 3FVQ ATP 0.001083 0.41808 4.63768
129 1T5C ADP 0.000002868 0.41244 4.63768
130 4QM7 GTP 0.0002204 0.4077 4.67836
131 3RAB GNP 0.00000000001544 0.75912 4.73373
132 1M7G ADX 0.0003787 0.46033 4.73934
133 1M7G ADP 0.0005309 0.45097 4.73934
134 1M7G AV2 0.000006092 0.44741 4.73934
135 5CK5 GDP 0.000000003823 0.55409 4.74684
136 2QQ0 TMP 0.002912 0.42393 4.8913
137 2QQ0 ANP 0.002937 0.42377 4.8913
138 2QQ0 THM 0.002708 0.42254 4.8913
139 2NCD ADP 0.00003392 0.55894 4.92754
140 4ZG4 VO4 ADP 0.000008095 0.51684 4.92754
141 1W7J ADP BEF 0.0001033 0.49073 4.92754
142 1P9B GDP 0.0002057 0.43986 4.92754
143 3TKA CTN 0.0105 0.43326 4.92754
144 5TSH ANP 0.0001008 0.41912 4.92754
145 4MKG AP5 0.004757 0.42292 5.06912
146 4MKF AP5 0.006554 0.41782 5.06912
147 1FP6 ADP 0.0003606 0.41958 5.19031
148 1AZT GSP 0.0000000003115 0.71388 5.21739
149 5BQ5 ADP BEF 0.0007008 0.4631 5.29101
150 2CHG ANP 0.0007509 0.41351 5.30973
151 3Q85 GNP 0.0000000002109 0.59984 5.32544
152 4WZA ACP 0.00009162 0.5176 5.43478
153 4WZA ADP 0.00009162 0.5176 5.43478
154 5KSZ GCP 0.0000006513 0.60459 5.50725
155 2FAH GDP 0.001159 0.40626 5.50725
156 1XKV ATP 0.0006909 0.40477 5.50725
157 5N69 ADP 0.00007108 0.50358 5.52764
158 1S3G AP5 0.006764 0.4162 5.52995
159 2G77 GDP 0.0000000001698 0.74886 5.55556
160 2G77 AF3 0.0000006752 0.6488 5.55556
161 3FB4 AP5 0.00604 0.41836 5.55556
162 5H56 TYD 0.003523 0.41769 5.64103
163 5H56 ADP 0.003523 0.41769 5.64103
164 4KFU ACP 0.000002569 0.44165 5.66038
165 2XTZ GSP 0.000000000268 0.7076 5.7971
166 1IHU ADP 0.0006002 0.43998 5.7971
167 1IHU AF3 0.0005905 0.43475 5.7971
168 1Z06 GNP 0.000000000004728 0.77683 5.82011
169 2IXE ATP 0.001224 0.42187 5.90406
170 1G3Q ADP 0.0001475 0.50058 5.90717
171 2F9L GDP 0.0000000241 0.62067 6.03015
172 2VB6 ADP BEF 0.0003052 0.45205 6.04027
173 5M04 GDP 0.0000000004604 0.78982 6.08696
174 2DPY ADP 0.002299 0.45912 6.08696
175 1QHH ATP 0.006095 0.42332 6.08696
176 2CE7 ADP 0.000335 0.41223 6.08696
177 1DS6 GDP 0.000000003105 0.56519 6.25
178 4YMU ATP 0.0001011 0.52172 6.25
179 1OIX GDP 0.0000000002545 0.70853 6.28272
180 1OIV GDP 0.00000001384 0.6364 6.28272
181 3CV2 OXL 0.01355 0.41027 6.37681
182 1ZD9 GDP 0.00000004005 0.63458 6.38298
183 3BER AMP 0.01409 0.40978 6.4257
184 1KSH GDP 0.00000000000632 0.74175 6.45161
185 3RWO GDP 0.00000001337 0.63702 6.48649
186 4V0K GDP 0.0000001113 0.58117 6.50888
187 4R2I ANP 0.0009033 0.48004 6.66667
188 2BIF SIN 0.003688 0.43088 6.66667
189 2BIF ANP 0.002152 0.43088 6.66667
190 5KDO GDP 0.0000007546 0.57202 6.75676
191 1GOT GDP 0.000001371 0.54148 6.84932
192 4C4P GNP 0.0000000002457 0.7123 6.93642
193 4OI4 ATP 0.0006719 0.43796 6.95652
194 2HV8 GTP 0.0000000004118 0.69984 6.97674
195 3UIE ANP 0.0001708 0.42475 7
196 2KIN ADP 0.000001285 0.42032 7
197 4BAS GNP 0.0000000001304 0.70293 7.03518
198 2HF9 GSP 0.0000001212 0.62151 7.07965
199 1TAD GDP 0.000000001712 0.68266 7.09877
200 1TAD ALF 0.000000001712 0.60701 7.09877
201 2D7C GTP 0.0000000003856 0.70103 7.18563
202 2GDJ ANP 0.0001431 0.4101 7.19697
203 4IEE AGS 0.0007019 0.47948 7.24638
204 4IOK ADP 0.002587 0.42044 7.24638
205 4IOK XPO 0.002052 0.41978 7.24638
206 1K6M AGS 0.003638 0.40779 7.24638
207 2RGX AP5 0.007573 0.41603 7.28155
208 1G8S MET 0.008381 0.43244 7.3913
209 2BEK ATP 0.001449 0.42781 7.393
210 3BOS CDP 0.00006945 0.41956 7.43802
211 2FH5 GTP 0.000000000007124 0.74019 7.47664
212 1ZJ6 G3D 0.0000000009955 0.59516 7.48663
213 1GXU 2HP 0.00524 0.4154 7.69231
214 1FZQ GDP 0.0000000004255 0.59626 7.73481
215 1YZG GDP 0.000000001006 0.59499 7.82123
216 4PFO ADP 0.0003065 0.45581 7.82609
217 2GJ8 ALF GDP 0.00000000009966 0.67189 8.13953
218 1PUJ GNP 0.0000000001322 0.65102 8.15603
219 1G16 GDP 0.00000003311 0.60586 8.23529
220 1JJV ATP 0.00004272 0.40592 8.25243
221 3B9Q MLI 0.0001994 0.50924 8.27815
222 4XTR ADP 0.0005631 0.45338 8.29493
223 4XTR ATP 0.0006033 0.43988 8.29493
224 4XVU ATP 0.0006938 0.43739 8.29493
225 5I0H ADP BEF 0.000002532 0.52259 8.4058
226 1F9V ADP 0.00002203 0.41352 8.4058
227 1GP2 GDP 0.000001662 0.5451 8.4507
228 5L3R GCP 0.00000229 0.52931 8.53242
229 2QEN ADP 0.0004336 0.42358 8.69565
230 3BC1 GNP 0.00000000006508 0.73315 8.71795
231 1F2U ATP 0.004556 0.40861 8.72483
232 2QZ4 ADP 0.0002831 0.41606 8.77863
233 4TTQ ATP 0.00005408 0.42855 8.83721
234 2WKQ GTP 0.0000000005113 0.68944 9.03614
235 4BQS ADP 0.0001965 0.50073 9.09091
236 3W5J GDP 0.00000002774 0.48003 9.31373
237 4LPS GDP 0.000000153 0.64313 9.50413
238 1R4A GNP 0.00000000008159 0.7257 9.69697
239 1GWN GTP 0.0000000002182 0.68328 9.7561
240 4PJ3 ANP 0.002311 0.43458 9.85507
241 5KSP GDP 0.0000003123 0.62833 10
242 3IIJ ADP 0.0001661 0.41289 10
243 3RLF ANP 0.001953 0.41891 10.1351
244 5GVR LMR 0.0001835 0.5127 10.2564
245 1DAK DPU 0.0001543 0.49081 10.2679
246 3A1S GDP 0.0000005514 0.61654 10.4651
247 3T12 GDP ALF 0.0000000002231 0.71343 10.6061
248 3T1O GDP 0.00000002735 0.56054 10.6061
249 2ODE ALF GDP 0.000000001927 0.60546 10.6383
250 1W5T ANP 0.002699 0.40274 10.7246
251 1M7B GTP 0.0000000001368 0.7321 10.8696
252 2A5F GTP 0.0000000001002 0.72202 10.8808
253 2ZEJ GDP 0.000001302 0.55671 11.413
254 3A4M ADP 0.00008364 0.40772 11.5385
255 5UWP GNP 0.00000000001186 0.77059 11.8143
256 5UWI GNP 0.00000000001129 0.76818 11.8143
257 5DIF GNP 0.00000000000894 0.71032 11.8143
258 5DHF GNP 0.000000000009715 0.70912 11.8143
259 5UWQ GNP 0.00000000001018 0.70838 11.8143
260 5UWJ GNP 0.00000000001033 0.70815 11.8143
261 5UWU GNP 0.00000000001111 0.70706 11.8143
262 5UWR GNP 0.00000000001133 0.70669 11.8143
263 5UWW GNP 0.00000000001142 0.70663 11.8143
264 5UWH GNP 0.00000000001381 0.70383 11.8143
265 5DI9 GNP 0.0000000000141 0.68848 11.8143
266 5UWS GNP 0.00000000001668 0.68627 11.8143
267 3REF GDP 0.00000000629 0.65263 11.8557
268 1XMV ADP 0.0001679 0.41605 11.8841
269 2IS6 ADP 0.0001535 0.4106 11.8841
270 1KO8 6PG 0.001644 0.40663 12
271 2ZPA ADP 0.0005203 0.42536 12.1739
272 3GJ0 GDP 0.000000000284 0.78656 12.6697
273 3GJ8 GDP 0.0000000001834 0.78269 12.6697
274 3GJ4 GDP 0.0000000002205 0.59907 12.6697
275 3M1I GTP 0.00000000002161 0.75641 12.7854
276 1YZQ GNP 0.000000000006689 0.77769 12.9412
277 4HAT GNP 0.00000000001026 0.77323 12.963
278 1IBR GNP 0.00000000001252 0.76631 12.963
279 5BXQ GDP 0.0000000002212 0.6156 12.963
280 3CH5 GDP 0.0000000003172 0.61145 12.963
281 1G7C 5GP 0.0000001468 0.52191 13.0435
282 4HI0 GDP 0.0000007785 0.57144 13.0653
283 2QTV GNP 0.0000000004608 0.69462 13.1737
284 3GJ7 GDP 0.0000000003353 0.59484 13.2653
285 2FFQ GSP 0.000000000006092 0.77938 13.4503
286 4CVN ADP 0.0002064 0.51308 13.6126
287 5UQW GDP 0.0000000008196 0.68428 13.7566
288 4DSU GDP 0.000000001266 0.68256 13.7566
289 5TAR GDP 0.000000001531 0.71647 14.0541
290 5TB5 GDP 0.0000000006905 0.60775 14.0541
291 3H4S ADP 0.000007488 0.4139 14.0741
292 2BCG GDP 0.000000006443 0.66924 14.0777
293 1F6B GDP 0.000000003427 0.58254 14.1414
294 4M9Q GNP 0.0000000000134 0.76463 14.5374
295 1JJ7 ADP 0.000006747 0.61227 14.6154
296 1NRJ GTP 0.0000000002068 0.68627 14.6789
297 3GJ5 GDP 0.0000000002247 0.61551 14.7059
298 1RYH GNP 0.0000000001274 0.63849 14.7783
299 3VX3 ADP 0.001429 0.41123 14.9194
300 5UWO GNP 0.00000000001177 0.70621 15
301 2C5L GTP 0.00000000000438 0.78537 15.0289
302 1MKY GDP 0.000000000114 0.60822 15.0725
303 4K81 GTP 0.00000000004481 0.74635 15.2047
304 5XCO GDP 0.00000000115 0.61516 15.2047
305 2BVN GNP 0.000000000001952 0.84851 15.3623
306 1D8T GDP 0.00000000009721 0.61275 15.3623
307 5O2T GSP 0.000000000007815 0.71253 15.3846
308 2A9K GDP 0.00000000365 0.60874 15.508
309 2J0V GDP 0.000000008101 0.5637 15.566
310 1LFD GNP 0.00000000000579 0.77682 15.5689
311 4RD0 GDP 0.0000000000009323 0.78865 15.6522
312 1NVV GNP 0.000000000006085 0.7794 15.6627
313 3DDC GNP 0.000000000009356 0.7716 15.6627
314 2UZI GTP 0.000000000009973 0.767 15.6627
315 1NVU GTP 0.00000000004873 0.74165 15.6627
316 5UFQ GNP 0.0000000002678 0.66883 15.6627
317 3KUD GDP 0.000000001781 0.64415 15.6627
318 1WQ1 GDP 0.000000008586 0.63909 15.6627
319 1WQ1 AF3 0.000002005 0.6264 15.6627
320 1CLU DBG 0.00000000314 0.4933 15.6627
321 3QBT GNP 0.000000000006417 0.73165 15.7143
322 1WA5 GTP 0.00000000002363 0.64221 15.9091
323 1D2E GDP 0.000000002265 0.60867 15.942
324 1GRN GDP 0.00000001676 0.58705 16.2304
325 2NGR GDP 0.00000000163 0.58588 16.2304
326 4ITR GDP 0.0000001106 0.56711 16.2304
327 2NGR AF3 0.000007271 0.44426 16.2304
328 1GRN AF3 0.000009267 0.44208 16.2304
329 1DAR GDP 0.000000003289 0.57406 16.2319
330 5KUT GDP 0.0000001705 0.52113 16.4021
331 1S9D GDP 0.000000005891 0.71071 16.4634
332 1RE0 GDP 0.0000000004004 0.57924 16.4634
333 1ZC3 GNP 0.0000000001331 0.72343 16.5714
334 2C78 GNP 0.0000000000004945 0.8247 16.8116
335 2C77 GNP 0.000000000000601 0.78211 16.8116
336 1UPT GTP 0.00000000002383 0.73201 16.9591
337 1U8Z GDP 0.000000001152 0.67494 17.2619
338 1Z08 GNP 0.00000001424 0.63006 17.6471
339 4DCT GDP 0.0000000001434 0.61889 17.6812
340 1Z2A GDP 0.000000082 0.59881 17.8571
341 1M2O GNP 0.0000000002866 0.70639 17.8947
342 1WF3 GNP 0.0000000001265 0.72434 17.9402
343 1B7T ADP 0.0002041 0.42282 17.9487
344 4HDO GNP 0.000000000006376 0.77855 17.9641
345 1GUA GNP 0.00000000001155 0.70591 17.9641
346 1KK1 GNP 0.0000000002164 0.58936 17.971
347 3GJ3 GDP 0.0000000003359 0.59468 18.1818
348 1KK8 BEF ADP 0.0001096 0.44519 18.1818
349 5HCN GCP 0.000000003979 0.71885 18.3908
350 1SVI GDP 0.0000000004327 0.58006 18.4615
351 3PQC GDP 0.00000005019 0.65653 18.9744
352 1OS1 PYR 0.003414 0.41827 19.4203
353 1OS1 ATP 0.003888 0.41446 19.4203
354 1X1R GDP 0.000000004977 0.65772 19.6629
355 2A5J GDP 0.0000000003813 0.75543 19.8953
356 1J2J GTP 0.00000000005278 0.72998 20
357 3KTA AP5 0.002312 0.40572 20.3297
358 1CS4 GSP 0.0000000002811 0.64507 20.4444
359 3ZIA ADP 0.0001053 0.44021 20.6349
360 3ZIA ATP 0.00004254 0.43839 20.6349
361 2GCO GNP 0.0000000001558 0.66293 20.8955
362 2GCN GDP 0.000000008559 0.62947 20.8955
363 1S8F GDP 0.0000000009105 0.69143 20.904
364 3ZS9 ADP ALF 0.00007751 0.45482 21.0526
365 1R2Q GNP 0.00000000001985 0.77854 21.1765
366 2WIC GNP 0.000000003595 0.72095 21.3483
367 3MJH GTP 0.000000000007056 0.73033 21.4286
368 1KAO GDP 0.00000001326 0.58836 21.5569
369 1CR1 TTP 0.002909 0.40224 21.6216
370 5UWT GNP 0.00000000001114 0.76842 21.7391
371 1E96 GTP 0.0000000001904 0.71377 21.875
372 1I4D GDP 0.00000001097 0.53869 21.875
373 3EC1 GDP 0.000000008496 0.5654 22.029
374 4R98 GNH 0.0000003006 0.63853 22.5092
375 4D0N GDP 0.000000005757 0.55673 22.7027
376 1OW3 GDP 0.000000008037 0.59864 22.7979
377 3SBD GNP 0.0000000001489 0.68025 22.9947
378 1MH1 GNP 0.0000000004478 0.64852 23.1183
379 2W2X GSP 0.00000000001994 0.72174 23.2432
380 1G4U GDP 0.0000001432 0.61041 23.3696
381 1G4U AF3 0.0001631 0.52399 23.3696
382 5GJC ATP 0.00002208 0.5472 23.7681
383 1Z0F GDP 0.0000000001104 0.61963 24.0223
384 2FJU GSP 0.0000000000336 0.71395 24.1573
385 1HE1 GDP 0.00000007203 0.61567 24.4318
386 1HE1 AF3 0.00004459 0.54737 24.4318
387 1CXZ GSP 0.0000000000317 0.72732 24.7253
388 5IRC GDP 0.00000001909 0.56459 24.7312
389 5HPY GDP 0.000000008348 0.59859 24.8649
390 1KMQ GNP 0.00000000008441 0.72159 25
391 2OM2 GDP 0.0000005682 0.57729 25
392 2JLR ANP 0.00009311 0.44084 25.5072
393 2WHX ADP 0.000006954 0.42368 25.5072
394 1TX4 ALF GDP 0.0000000001432 0.71216 25.9887
395 3WXM GTP 0.0000000000002919 0.83074 26.3982
396 1Z0A GDP 0.0000000004532 0.61439 26.4368
397 3T5G GDP 0.0000000006344 0.61168 26.5193
398 1XTQ GDP 0.0000000003207 0.69777 27.1186
399 1NF3 GNP 0.0000000003165 0.66805 27.1795
400 1A4R GDP 0.000000001292 0.64151 27.2251
401 1A4R GNH 0.000000001458 0.62913 27.2251
402 2QN6 GDP 0.00000000005471 0.60611 27.7778
403 4NON GDP 0.00000008304 0.55549 28.8462
404 1Z0K GTP 0.000000000007388 0.76507 29.0698
405 4DID GDP 0.00000001384 0.55893 29.5337
406 2BME GNP 0.000000000003196 0.78754 29.5699
407 1KY3 GDP 0.000000002878 0.60214 30.2198
408 1FQJ ALF 0.0000002504 0.67183 30.9524
409 1FQJ GDP 0.0000001254 0.59123 30.9524
410 1VG1 GDP 0.0000000002867 0.60696 31.3514
411 1VG9 GDP 0.0000000006646 0.59811 31.3514
412 1D5C GDP 0.000000002711 0.61438 31.4815
413 1TU3 GNP 0.00000000001785 0.75649 31.6456
414 1EK0 GNP 0.00000000002138 0.75324 31.7647
415 2WJG GDP 0.000000005913 0.72203 32.4468
416 1SKQ GDP 0.000000001095 0.57218 33.3333
417 1VG8 GNP 0.00000000001179 0.7674 33.8164
418 1VG0 GDP 0.000000002623 0.60205 33.8164
419 2WJH GDP 0.000000007079 0.57429 36.1446
420 2WJH FLC 0.000000789 0.50896 36.1446
421 1Z0J GTP 0.00000000002219 0.69638 36.4706
422 1YVD GNP 0.00000000001794 0.7564 37.2781
423 2HCJ GDP 0.00000000002505 0.6133 37.8378
424 4B47 GDP 0.00000000001859 0.61809 38.2609
Pocket No.: 2; Query (leader) PDB : 4TMZ; Ligand: GSP; Similar sites found: 3
This union binding pocket(no: 2) in the query (biounit: 4tmz.bio1) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3WWX DIA 0.01911 0.41404 1.15942
2 5KGS 6SR 0.01948 0.40043 2.6087
3 4UOX PUT 0.013 0.40025 2.6087
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