Receptor
PDB id Resolution Class Description Source Keywords
4TYL 1.85 Å EC: 3.6.1.3 FRAGMENT-BASED SCREENING OF THE BROMODOMAIN OF ATAD2 HOMO SAPIENS BROMODOMAIN HYDROLASE-HYDROLASE INHIBITOR COMPLEX
Ref.: FRAGMENT-BASED SCREENING OF THE BROMODOMAIN OF ATAD J.MED.CHEM. V. 57 9687 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CL A:1206;
A:1204;
A:1202;
A:1205;
 Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
 submit data
35.453 Cl [Cl-]
39O A:1203;
 Valid;
 none;
 Kd = 600 uM
191.23 C10 H13 N3 O Cc1cc...
SO4 A:1201;
 Invalid;
 none;
 submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6HDN 1.9 Å EC: 3.6.1.3 CRYSTAL STRUCTURE OF HUMAN ATAD2 BROMODOMAIN IN COMPLEX WITH 8-((8-METHYL-8-AZABICYCLOOCTAN-3-YL)AMINO)-1,7-NAPHTHYRIDIN HOMO SAPIENS INHIBITOR ATAD2 BROMODOMAIN EPIGENETICS ATPASE FAMILY AACONTAINING PROTEIN 2 TRANSCRIPTION
Ref.: AIMING TO MISS A MOVING TARGET: BROMO AND EXTRA TER DOMAIN (BET) SELECTIVITY IN CONSTRAINED ATAD2 INHIB J. MED. CHEM. V. 61 8321 2018
Members (18)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 6 families.
1 5A5R ic50 = 1.3 uM NP8 C20 H23 N5 O2 CC1=Cc2c(c....
2 5A82 ic50 = 2.51 uM YEJ C20 H28 N4 O4 S CC1=Cc2ccn....
3 5A5Q Kd = 21 uM 6XC C14 H18 N4 O CC1=Cc2ccn....
4 6S55 - KW5 C17 H21 Br N4 O5 S C[C@H]1CCC....
5 5A81 Kd = 2.9 uM 78J C21 H30 N4 O2 CC1=Cc2ccn....
6 5A5P ic50 = 0.1 mM JTF C14 H19 N3 O CC1=Cc2ccc....
7 4TU4 Kd = 175 uM 37N C18 H16 N2 O5 S Cc1c(c(on1....
8 4TZ8 Kd = 500 uM 39U C9 H13 N3 O S CC1(Cc2c(s....
9 5A5O - J5I C10 H9 N O CC1=Cc2ccc....
10 6HDN ic50 = 3.16 uM FZB C17 H22 N4 O CC1=Cc2ccn....
11 6S57 - KVT C20 H28 N4 O5 S Cc1ccc(cc1....
12 5A5N - 8WS C11 H21 N3 O3 CC(=O)NCCC....
13 4TTE Kd = 202 uM 36Z C13 H14 N2 O3 Cc1c(c(on1....
14 4TYL Kd = 600 uM 39O C10 H13 N3 O Cc1cc2c(cc....
15 4TZ2 Kd = 350 uM 39R C14 H12 N4 c1ccc(cc1)....
16 5A83 ic50 = 0.158 uM YD3 C27 H34 N4 O4 S Cc1cc(cnc1....
17 5LJ0 ic50 = 0.00000001 M 6XX C28 H35 F2 N5 O3 Cc1cc(cnc1....
18 6S56 - KVZ C22 H23 Cl N4 O5 S CN(C)S(=O)....
70% Homology Family (19)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 5A5R ic50 = 1.3 uM NP8 C20 H23 N5 O2 CC1=Cc2c(c....
2 5A82 ic50 = 2.51 uM YEJ C20 H28 N4 O4 S CC1=Cc2ccn....
3 5A5Q Kd = 21 uM 6XC C14 H18 N4 O CC1=Cc2ccn....
4 6S55 - KW5 C17 H21 Br N4 O5 S C[C@H]1CCC....
5 5A81 Kd = 2.9 uM 78J C21 H30 N4 O2 CC1=Cc2ccn....
6 5A5P ic50 = 0.1 mM JTF C14 H19 N3 O CC1=Cc2ccc....
7 4TU4 Kd = 175 uM 37N C18 H16 N2 O5 S Cc1c(c(on1....
8 4TZ8 Kd = 500 uM 39U C9 H13 N3 O S CC1(Cc2c(s....
9 5A5O - J5I C10 H9 N O CC1=Cc2ccc....
10 6HDN ic50 = 3.16 uM FZB C17 H22 N4 O CC1=Cc2ccn....
11 6S57 - KVT C20 H28 N4 O5 S Cc1ccc(cc1....
12 5A5N - 8WS C11 H21 N3 O3 CC(=O)NCCC....
13 4TTE Kd = 202 uM 36Z C13 H14 N2 O3 Cc1c(c(on1....
14 4TYL Kd = 600 uM 39O C10 H13 N3 O Cc1cc2c(cc....
15 4TZ2 Kd = 350 uM 39R C14 H12 N4 c1ccc(cc1)....
16 5A83 ic50 = 0.158 uM YD3 C27 H34 N4 O4 S Cc1cc(cnc1....
17 5LJ0 ic50 = 0.00000001 M 6XX C28 H35 F2 N5 O3 Cc1cc(cnc1....
18 6S56 - KVZ C22 H23 Cl N4 O5 S CN(C)S(=O)....
19 6VEO - YD4 C26 H33 N5 O4 S Cc1cc(cnc1....
50% Homology Family (19)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 5A5R ic50 = 1.3 uM NP8 C20 H23 N5 O2 CC1=Cc2c(c....
2 5A82 ic50 = 2.51 uM YEJ C20 H28 N4 O4 S CC1=Cc2ccn....
3 5A5Q Kd = 21 uM 6XC C14 H18 N4 O CC1=Cc2ccn....
4 6S55 - KW5 C17 H21 Br N4 O5 S C[C@H]1CCC....
5 5A81 Kd = 2.9 uM 78J C21 H30 N4 O2 CC1=Cc2ccn....
6 5A5P ic50 = 0.1 mM JTF C14 H19 N3 O CC1=Cc2ccc....
7 4TU4 Kd = 175 uM 37N C18 H16 N2 O5 S Cc1c(c(on1....
8 4TZ8 Kd = 500 uM 39U C9 H13 N3 O S CC1(Cc2c(s....
9 5A5O - J5I C10 H9 N O CC1=Cc2ccc....
10 6HDN ic50 = 3.16 uM FZB C17 H22 N4 O CC1=Cc2ccn....
11 6S57 - KVT C20 H28 N4 O5 S Cc1ccc(cc1....
12 5A5N - 8WS C11 H21 N3 O3 CC(=O)NCCC....
13 4TTE Kd = 202 uM 36Z C13 H14 N2 O3 Cc1c(c(on1....
14 4TYL Kd = 600 uM 39O C10 H13 N3 O Cc1cc2c(cc....
15 4TZ2 Kd = 350 uM 39R C14 H12 N4 c1ccc(cc1)....
16 5A83 ic50 = 0.158 uM YD3 C27 H34 N4 O4 S Cc1cc(cnc1....
17 5LJ0 ic50 = 0.00000001 M 6XX C28 H35 F2 N5 O3 Cc1cc(cnc1....
18 6S56 - KVZ C22 H23 Cl N4 O5 S CN(C)S(=O)....
19 6VEO - YD4 C26 H33 N5 O4 S Cc1cc(cnc1....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 39O; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 39O 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: 39O; Similar ligands found: 813
No: Ligand Similarity coefficient
1 3PF 0.9605
2 TOF 0.9571
3 R8V 0.9557
4 D48 0.9546
5 GDE 0.9544
6 1KP 0.9543
7 5QY 0.9532
8 AZ9 0.9528
9 AJY 0.9504
10 12Q 0.9496
11 G3E 0.9492
12 SE2 0.9491
13 BDP 0.9490
14 KUF 0.9487
15 AJV 0.9479
16 0N7 0.9477
17 HQD 0.9466
18 CWS 0.9458
19 J5I 0.9456
20 APZ 0.9453
21 JG8 0.9451
22 I6G 0.9451
23 8W9 0.9440
24 0P6 0.9438
25 TTL 0.9436
26 2HQ 0.9430
27 KT7 0.9429
28 HQT 0.9425
29 4Z4 0.9423
30 DIN 0.9420
31 QSH 0.9418
32 2FQ 0.9415
33 PXL 0.9413
34 KJH 0.9409
35 SKA 0.9409
36 7W1 0.9407
37 86J 0.9406
38 15E 0.9406
39 8CM 0.9399
40 GVG 0.9394
41 BGC 0.9394
42 E7Z 0.9392
43 ZYR 0.9386
44 A7W 0.9382
45 0W1 0.9375
46 5QX 0.9373
47 SKM 0.9368
48 6QF 0.9367
49 MUA 0.9364
50 MRW 0.9363
51 6RQ 0.9360
52 GTR 0.9359
53 0FO 0.9358
54 UFO 0.9357
55 FGZ 0.9356
56 9FL 0.9353
57 IV2 0.9352
58 SYV 0.9351
59 CFF 0.9346
60 0XT 0.9341
61 N8Y 0.9339
62 CH9 0.9335
63 1IT 0.9331
64 9CA 0.9331
65 BEA 0.9330
66 15L 0.9330
67 30G 0.9329
68 CLZ 0.9328
69 LT2 0.9328
70 A29 0.9327
71 28N 0.9315
72 1A7 0.9315
73 B62 0.9312
74 XHP 0.9311
75 TIY 0.9301
76 4NC 0.9301
77 GLC 0.9300
78 ESI 0.9291
79 ANC 0.9286
80 KKN 0.9286
81 3Z8 0.9283
82 G12 0.9281
83 2AK 0.9280
84 2LY 0.9279
85 V1T 0.9275
86 INO 0.9273
87 4AA 0.9270
88 6X9 0.9267
89 ROI 0.9264
90 7WR 0.9264
91 PEY 0.9264
92 LDR 0.9263
93 E7S 0.9259
94 3IT 0.9256
95 AN3 0.9254
96 PHH 0.9253
97 EN1 0.9251
98 JLZ 0.9251
99 DHB 0.9248
100 4MU 0.9245
101 BPU 0.9241
102 7B3 0.9239
103 DQU 0.9239
104 CHB 0.9237
105 173 0.9233
106 P9P 0.9231
107 6ME 0.9230
108 4A3 0.9227
109 92P 0.9227
110 OTW 0.9226
111 44W 0.9224
112 B60 0.9224
113 3QV 0.9221
114 9AP 0.9220
115 DHK 0.9219
116 97T 0.9217
117 5WV 0.9217
118 FHB 0.9216
119 VXX 0.9215
120 93K 0.9215
121 DPZ 0.9215
122 KTW 0.9215
123 68A 0.9212
124 HKD 0.9212
125 92K 0.9211
126 NNO 0.9210
127 BPY 0.9210
128 5VL 0.9206
129 MYJ 0.9205
130 4RU 0.9204
131 3HM 0.9202
132 BZJ 0.9202
133 0FN 0.9197
134 37T 0.9197
135 4JQ 0.9197
136 J9Q 0.9196
137 MAQ 0.9195
138 MQN 0.9194
139 MVN 0.9191
140 R9Y 0.9191
141 GJP 0.9190
142 8WO 0.9189
143 DMD 0.9187
144 0HN 0.9185
145 C2Y 0.9185
146 344 0.9185
147 15N 0.9185
148 ES7 0.9183
149 8WT 0.9180
150 ISN 0.9179
151 UFV 0.9176
152 1P7 0.9174
153 5RO 0.9173
154 OCH 0.9173
155 2HO 0.9172
156 1HN 0.9172
157 9MG 0.9170
158 5TY 0.9166
159 KJU 0.9166
160 COU 0.9165
161 9TW 0.9165
162 DX3 0.9164
163 XX2 0.9163
164 CTL 0.9162
165 X11 0.9161
166 G3F 0.9160
167 1LQ 0.9160
168 44V 0.9160
169 3ID 0.9159
170 1NP 0.9157
171 0FK 0.9155
172 BZ2 0.9155
173 0HO 0.9154
174 3A9 0.9151
175 226 0.9150
176 GNM 0.9146
177 AA 0.9146
178 EGR 0.9146
179 UNC 0.9144
180 8HC 0.9144
181 JB5 0.9143
182 1SQ 0.9143
183 8S0 0.9143
184 X8D 0.9141
185 6BL 0.9141
186 GCS 0.9140
187 0JD 0.9140
188 H42 0.9139
189 IHB 0.9138
190 3J8 0.9137
191 0TU 0.9137
192 MSR 0.9136
193 DPT 0.9136
194 03V 0.9134
195 ABI 0.9132
196 2AQ 0.9132
197 FDR 0.9132
198 4FS 0.9130
199 ES5 0.9128
200 DNA 0.9126
201 2ZM 0.9125
202 BZE 0.9125
203 FLV 0.9124
204 3NY 0.9123
205 2HU 0.9122
206 ES1 0.9121
207 RXA 0.9120
208 ESP 0.9119
209 AJ2 0.9119
210 0BP 0.9117
211 9KT 0.9116
212 E1T 0.9115
213 F31 0.9115
214 ICB 0.9114
215 9FE 0.9113
216 GTQ 0.9112
217 9R5 0.9111
218 6NT 0.9111
219 1F1 0.9108
220 DNF 0.9108
221 VNL 0.9108
222 495 0.9106
223 32X 0.9106
224 L22 0.9104
225 4YO 0.9104
226 MT0 0.9104
227 O72 0.9104
228 GZL 0.9103
229 N2I 0.9103
230 QWN 0.9103
231 24W 0.9102
232 TT4 0.9101
233 NCT 0.9101
234 EA1 0.9100
235 H5B 0.9099
236 MPV 0.9098
237 5SG 0.9098
238 5NI 0.9098
239 HA5 0.9094
240 VK3 0.9093
241 FBB 0.9092
242 4P5 0.9090
243 ANF 0.9088
244 5GU 0.9088
245 5Q0 0.9088
246 PJW 0.9088
247 5RN 0.9086
248 JPZ 0.9086
249 5IQ 0.9086
250 HQJ 0.9085
251 N5J 0.9085
252 JDN 0.9084
253 JR2 0.9083
254 PH2 0.9080
255 6NI 0.9080
256 N0Z 0.9079
257 12T 0.9078
258 QXW 0.9078
259 4YS 0.9078
260 4HC 0.9078
261 ESX 0.9077
262 4ME 0.9076
263 JAW 0.9073
264 LI6 0.9070
265 SXS 0.9069
266 DHQ 0.9068
267 Z5P 0.9068
268 MS9 0.9068
269 7W4 0.9066
270 2AL 0.9066
271 0F9 0.9066
272 GCU 0.9064
273 8XL 0.9064
274 KGK 0.9064
275 PYQ 0.9064
276 AY4 0.9064
277 L5V 0.9063
278 HQY 0.9063
279 VGD 0.9062
280 AZ8 0.9060
281 8NX 0.9060
282 NDH 0.9060
283 L99 0.9059
284 HIS 0.9059
285 ES2 0.9057
286 M5K 0.9057
287 KYA 0.9055
288 HHR 0.9054
289 XQ0 0.9053
290 NQ 0.9051
291 5RG 0.9051
292 K2T 0.9050
293 CK2 0.9045
294 0W8 0.9044
295 IWT 0.9043
296 4WL 0.9043
297 ORO 0.9042
298 4VS 0.9042
299 HBO 0.9040
300 F4E 0.9039
301 AQO 0.9038
302 JU2 0.9038
303 TWO 0.9036
304 27B 0.9035
305 67N 0.9035
306 C2U 0.9035
307 QPR 0.9035
308 ET2 0.9034
309 1QP 0.9032
310 OXC 0.9032
311 HJP 0.9032
312 5B1 0.9031
313 EXD 0.9030
314 4XH 0.9030
315 SYA 0.9029
316 BNL 0.9027
317 GAL 0.9027
318 8ZE 0.9026
319 SYR 0.9026
320 M2K 0.9025
321 MXD 0.9020
322 DNC 0.9020
323 K44 0.9019
324 URC 0.9018
325 L7T 0.9018
326 36R 0.9018
327 4ZA 0.9018
328 SNU 0.9018
329 BSP 0.9017
330 M0Q 0.9016
331 6TZ 0.9015
332 Q71 0.9015
333 ONR 0.9015
334 FOT 0.9015
335 4V2 0.9015
336 TZF 0.9014
337 1P8 0.9013
338 FA0 0.9013
339 F2W 0.9013
340 HDH 0.9012
341 CLW 0.9010
342 QWW 0.9010
343 ODO 0.9010
344 BIK 0.9008
345 7VS 0.9008
346 2K8 0.9006
347 M0W 0.9005
348 1XN 0.9005
349 PE0 0.9005
350 Q6T 0.9005
351 Q88 0.9004
352 4M0 0.9002
353 54G 0.8998
354 NDM 0.8997
355 MEW 0.8997
356 6CS 0.8996
357 PHB 0.8996
358 FHC 0.8996
359 HH8 0.8996
360 DOB 0.8995
361 2D0 0.8994
362 SLS 0.8993
363 3WA 0.8992
364 4SX 0.8990
365 GF4 0.8990
366 BHA 0.8989
367 CCV 0.8989
368 7B4 0.8989
369 7MX 0.8989
370 NAG 0.8987
371 M1H 0.8986
372 94W 0.8986
373 Q24 0.8985
374 2FY 0.8984
375 CWM 0.8982
376 THA 0.8982
377 ICO 0.8981
378 5M0 0.8980
379 OA3 0.8979
380 K6X 0.8978
381 JBQ 0.8978
382 X0U 0.8976
383 NPO 0.8975
384 X0V 0.8975
385 5VM 0.8975
386 20J 0.8974
387 AW5 0.8972
388 INE 0.8972
389 J9W 0.8972
390 HBD 0.8971
391 MOK 0.8971
392 HLZ 0.8968
393 NID 0.8968
394 NTZ 0.8967
395 QX4 0.8967
396 FF2 0.8967
397 6KT 0.8966
398 209 0.8962
399 D07 0.8962
400 5CU 0.8960
401 M1A 0.8959
402 DRG 0.8958
403 R20 0.8957
404 MO8 0.8956
405 64C 0.8956
406 PFB 0.8955
407 CPZ 0.8953
408 A5E 0.8953
409 X48 0.8952
410 ES0 0.8952
411 9ZE 0.8952
412 ADZ 0.8950
413 4XV 0.8950
414 IJZ 0.8950
415 CTS 0.8948
416 5WY 0.8948
417 4TU 0.8944
418 C9E 0.8944
419 JYB 0.8944
420 54X 0.8942
421 1XA 0.8942
422 PIY 0.8941
423 DRL 0.8940
424 PBZ 0.8940
425 8TX 0.8940
426 537 0.8939
427 DEE 0.8938
428 5NU 0.8938
429 HZQ 0.8938
430 HHS 0.8937
431 8MO 0.8935
432 KJ5 0.8934
433 TGX 0.8934
434 EKZ 0.8932
435 CWJ 0.8930
436 PQ0 0.8930
437 TEP 0.8930
438 ZME 0.8929
439 Q7A 0.8929
440 KTJ 0.8928
441 QBK 0.8928
442 5MK 0.8927
443 PAB 0.8927
444 52C 0.8925
445 M1Q 0.8925
446 9TZ 0.8925
447 9UL 0.8925
448 5OB 0.8924
449 UNJ 0.8923
450 DBH 0.8923
451 JXN 0.8923
452 4KL 0.8922
453 4JT 0.8922
454 M6N 0.8922
455 069 0.8920
456 D1X 0.8920
457 JUG 0.8919
458 LNR 0.8919
459 3HA 0.8919
460 XIY 0.8917
461 KJY 0.8917
462 4MA 0.8914
463 LDP 0.8914
464 EVA 0.8914
465 4XS 0.8914
466 IFP 0.8913
467 JP2 0.8911
468 826 0.8911
469 M5H 0.8910
470 4FH 0.8910
471 1Y6 0.8910
472 4BL 0.8910
473 2BG 0.8910
474 6FB 0.8909
475 PRF 0.8909
476 MWP 0.8907
477 LGC 0.8906
478 X0W 0.8906
479 3M0 0.8905
480 GCB 0.8904
481 PIM 0.8903
482 ADA 0.8903
483 149 0.8902
484 BZ3 0.8902
485 SX1 0.8902
486 JBH 0.8900
487 5LA 0.8897
488 7ZE 0.8897
489 F6P 0.8896
490 QIC 0.8896
491 KDV 0.8896
492 B5D 0.8895
493 JTH 0.8895
494 75K 0.8894
495 PQK 0.8894
496 2H5 0.8893
497 H4E 0.8892
498 G1O 0.8890
499 3F0 0.8889
500 DIU 0.8888
501 DOR 0.8888
502 SHG 0.8887
503 Q77 0.8887
504 AKH 0.8887
505 7NI 0.8885
506 428 0.8885
507 692 0.8881
508 E35 0.8880
509 ASO 0.8879
510 42C 0.8879
511 J6W 0.8878
512 4BY 0.8873
513 SOR 0.8873
514 4AN 0.8872
515 B57 0.8871
516 AC6 0.8867
517 ISZ 0.8867
518 7MU 0.8867
519 6FZ 0.8865
520 4CS 0.8865
521 SRO 0.8864
522 8XQ 0.8864
523 J9T 0.8863
524 TTY 0.8862
525 H33 0.8860
526 K32 0.8860
527 SWA 0.8860
528 F12 0.8859
529 QUZ 0.8857
530 3ZB 0.8856
531 LL1 0.8855
532 CFI 0.8854
533 FE DB1 0.8854
534 XAZ 0.8854
535 GM7 0.8854
536 3HB 0.8853
537 QAS 0.8852
538 1LM 0.8850
539 NPY 0.8850
540 5VJ 0.8850
541 2HC 0.8849
542 GJS 0.8849
543 1M2 0.8848
544 BHO 0.8848
545 DBJ 0.8847
546 ZVO 0.8847
547 6E8 0.8846
548 BTY 0.8846
549 FQX 0.8845
550 PZI 0.8844
551 GZ8 0.8842
552 L5E 0.8842
553 LKA 0.8842
554 KW8 0.8840
555 5XC 0.8840
556 2O6 0.8840
557 2ZQ 0.8839
558 K25 0.8838
559 UAN 0.8838
560 7ME 0.8835
561 QSB 0.8835
562 P72 0.8834
563 SHA 0.8833
564 ABV 0.8832
565 XQK 0.8832
566 APG 0.8830
567 7VP 0.8830
568 PHU 0.8827
569 K97 0.8827
570 5JQ 0.8826
571 5NS 0.8826
572 I3A 0.8823
573 3R4 0.8821
574 GO8 0.8821
575 TYL 0.8819
576 HNQ 0.8818
577 AX7 0.8818
578 DBX 0.8817
579 2FG 0.8816
580 A13 0.8816
581 SW7 0.8815
582 RM1 0.8814
583 HX4 0.8812
584 RMN 0.8812
585 36E 0.8811
586 GHM 0.8809
587 J9N 0.8807
588 PBA 0.8806
589 JA8 0.8805
590 PPY 0.8803
591 LSA 0.8803
592 1GN 0.8802
593 MAJ 0.8800
594 X05 0.8800
595 B55 0.8800
596 1Z6 0.8800
597 6M9 0.8798
598 AZA 0.8798
599 E3D 0.8796
600 174 0.8796
601 QAT 0.8796
602 8OZ 0.8795
603 8GC 0.8794
604 GLA 0.8794
605 GUN 0.8793
606 53C 0.8793
607 OMD 0.8792
608 3TJ 0.8792
609 PNZ 0.8792
610 36Y 0.8791
611 SVN 0.8790
612 3NT 0.8789
613 SG2 0.8788
614 PHE 0.8788
615 ANN 0.8787
616 2KA 0.8786
617 2EC 0.8786
618 45L 0.8784
619 BA5 0.8784
620 Z82 0.8784
621 NIZ 0.8784
622 JY4 0.8783
623 2F6 0.8783
624 FUD 0.8781
625 JF2 0.8780
626 JF1 0.8777
627 JAE 0.8776
628 3R6 0.8772
629 BZX 0.8771
630 39A 0.8770
631 PD2 0.8769
632 CXH 0.8768
633 QX2 0.8768
634 MR1 0.8767
635 PDC 0.8766
636 XDE 0.8766
637 4NB 0.8765
638 JTA 0.8763
639 GXY 0.8762
640 E1K 0.8762
641 K34 0.8759
642 270 0.8757
643 F05 0.8757
644 5JL 0.8756
645 IGA 0.8755
646 GYE 0.8755
647 GCW 0.8754
648 XM5 0.8754
649 61M 0.8753
650 FBU 0.8753
651 3AB 0.8753
652 7I2 0.8752
653 JB8 0.8752
654 3MB 0.8751
655 K17 0.8750
656 WCE 0.8750
657 3Y7 0.8750
658 FDB 0.8750
659 14O 0.8748
660 D3G 0.8747
661 JND 0.8746
662 OVV 0.8746
663 GNV 0.8745
664 5HN 0.8743
665 RUY 0.8743
666 EYK 0.8741
667 K22 0.8740
668 ENO 0.8740
669 HRM 0.8739
670 5H1 0.8737
671 7HQ 0.8736
672 S60 0.8736
673 KFH 0.8735
674 CB1 0.8734
675 582 0.8734
676 GAB 0.8734
677 23J 0.8733
678 5NE 0.8733
679 M4E 0.8732
680 APS 0.8731
681 OTR 0.8730
682 1DW 0.8730
683 PRZ 0.8730
684 F60 0.8730
685 BGU 0.8729
686 5MI 0.8728
687 AMR 0.8725
688 3MG 0.8725
689 PX7 0.8724
690 P92 0.8723
691 YQA 0.8723
692 TH7 0.8723
693 SAL 0.8723
694 GZ2 0.8722
695 1WC 0.8719
696 ES9 0.8719
697 TBS 0.8718
698 NMJ 0.8715
699 8IG 0.8710
700 2K4 0.8710
701 11S 0.8710
702 GIV 0.8709
703 LZ2 0.8708
704 CFP 0.8708
705 18N 0.8708
706 0RW 0.8707
707 6AI 0.8706
708 8NB 0.8706
709 5MB 0.8705
710 795 0.8704
711 M1Z 0.8701
712 ASC 0.8698
713 O2A 0.8696
714 2MI 0.8696
715 B21 0.8696
716 FK1 0.8695
717 9EW 0.8694
718 BP7 0.8691
719 F9Y 0.8690
720 4I8 0.8688
721 2CK 0.8687
722 12B 0.8685
723 78Y 0.8682
724 H4N 0.8681
725 BRT 0.8681
726 HHA 0.8680
727 6M4 0.8679
728 NVU 0.8676
729 LQ2 0.8675
730 MJ2 0.8674
731 CNI 0.8673
732 M3H 0.8672
733 W8G 0.8672
734 2QC 0.8672
735 6VD 0.8668
736 HMH 0.8668
737 3BZ 0.8663
738 OVM 0.8661
739 TRP 0.8660
740 EQT 0.8659
741 DDU 0.8657
742 DXK 0.8656
743 BE2 0.8656
744 LZM 0.8653
745 WUB 0.8649
746 R2P 0.8649
747 EVF 0.8645
748 X09 0.8645
749 B56 0.8643
750 A2F 0.8643
751 FBM 0.8642
752 EJZ 0.8641
753 42A 0.8639
754 CKA 0.8638
755 82I 0.8637
756 GVY 0.8636
757 I3E 0.8634
758 THM 0.8633
759 9TF 0.8628
760 HLD 0.8627
761 GV9 0.8624
762 ITE 0.8624
763 64E 0.8624
764 8WZ 0.8623
765 2JK 0.8622
766 7WV 0.8618
767 YH7 0.8618
768 Q02 0.8617
769 TMG 0.8613
770 4V6 0.8612
771 EMZ 0.8610
772 V55 0.8609
773 PRL 0.8607
774 ES6 0.8606
775 6OT 0.8605
776 XFE 0.8602
777 JBK 0.8602
778 K5W 0.8601
779 DK1 0.8600
780 IPB 0.8600
781 HLR 0.8600
782 8NY 0.8597
783 4NM 0.8594
784 JRO 0.8591
785 MHK 0.8589
786 M6Z 0.8588
787 DHR 0.8588
788 LAO 0.8588
789 FCR 0.8587
790 MT5 0.8587
791 PO6 0.8580
792 680 0.8580
793 3QM 0.8580
794 DX1 0.8580
795 KYN 0.8580
796 GOE 0.8579
797 3U4 0.8576
798 K8X 0.8575
799 K37 0.8571
800 AX3 0.8571
801 S0E 0.8566
802 6AP 0.8565
803 1X8 0.8561
804 GNY 0.8561
805 0NX 0.8557
806 N2M 0.8556
807 P7Y 0.8556
808 6GU 0.8552
809 505 0.8544
810 XCG 0.8542
811 9RW 0.8540
812 KBB 0.8534
813 0FR 0.8526
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6HDN; Ligand: FZB; Similar sites found with APoc: 10
This union binding pocket(no: 1) in the query (biounit: 6hdn.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 4XUB 43D 27.3504
2 6HAZ FX5 27.6423
3 6HAZ FX5 27.6423
4 6DF7 G9V 30.7692
5 6DF7 G9V 30.7692
6 6J3O B4L 30.7692
7 6J3P B8O 39.2308
8 6J3P B8O 39.2308
9 5MG2 7M8 40
10 5IGL BMF 46.9231
11 5MLJ 9ST 50
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