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Receptor
PDB id Resolution Class Description Source Keywords
4U0S 2.49 Å EC: 2.7.7.- STRUCTURE OF EUKARYOTIC FIC DOMAIN CONTAINING PROTEIN WITH A HOMO SAPIENS TPR FIC ADP ADENYLATION TRANSFERASE
Ref.: CRYSTAL STRUCTURE OF THE HUMAN, FIC-DOMAIN CONTAINI PROTEIN HYPE AND IMPLICATIONS FOR ITS FUNCTIONS. STRUCTURE V. 22 1831 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG B:502;
A:502;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
ADP A:501;
B:501;
Valid;
Valid;
none;
none;
Kd = 160 nM
427.201 C10 H15 N5 O10 P2 c1nc(...
PG4 B:503;
A:503;
Invalid;
Invalid;
none;
none;
submit data
194.226 C8 H18 O5 C(COC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4U0S 2.49 Å EC: 2.7.7.- STRUCTURE OF EUKARYOTIC FIC DOMAIN CONTAINING PROTEIN WITH A HOMO SAPIENS TPR FIC ADP ADENYLATION TRANSFERASE
Ref.: CRYSTAL STRUCTURE OF THE HUMAN, FIC-DOMAIN CONTAINI PROTEIN HYPE AND IMPLICATIONS FOR ITS FUNCTIONS. STRUCTURE V. 22 1831 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 21 families.
1 4U0S Kd = 160 nM ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 20 families.
1 4U0S Kd = 160 nM ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 19 families.
1 4U0S Kd = 160 nM ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADP; Similar ligands found: 452
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 HEJ 0.9 1
3 ATP 0.9 1
4 A2D 0.895522 0.971831
5 5FA 0.887324 1
6 AQP 0.887324 1
7 AP5 0.884058 0.971831
8 B4P 0.884058 0.971831
9 BA3 0.869565 0.971831
10 AN2 0.84507 0.985915
11 AT4 0.84507 0.958904
12 M33 0.833333 0.958333
13 ACQ 0.826667 0.972222
14 A 0.823529 0.971429
15 AMP 0.823529 0.971429
16 ACP 0.821918 0.972222
17 6YZ 0.818182 0.972222
18 APR 0.810811 0.971831
19 AR6 0.810811 0.971831
20 ANP 0.802632 0.972222
21 SAP 0.8 0.945946
22 AGS 0.8 0.945946
23 AD9 0.8 0.972222
24 ADX 0.783784 0.873418
25 CA0 0.783784 0.945205
26 TAT 0.779221 0.958904
27 T99 0.779221 0.958904
28 50T 0.773333 0.958333
29 ABM 0.763889 0.917808
30 APC 0.763158 0.958904
31 PRX 0.763158 0.893333
32 ATF 0.759494 0.958904
33 A22 0.753086 0.985915
34 AP2 0.743243 0.958904
35 A12 0.743243 0.958904
36 SRA 0.736111 0.918919
37 ADQ 0.73494 0.945205
38 25L 0.732558 0.985915
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 A3R 0.714286 0.907895
44 ATR 0.708861 0.971429
45 ADP PO3 0.708861 0.943662
46 PAP 0.708861 0.985714
47 SRP 0.707317 0.906667
48 7D3 0.706667 0.905405
49 25A 0.702381 0.971831
50 9X8 0.697674 0.92
51 OAD 0.697674 0.945205
52 RBY 0.6875 0.932432
53 ADV 0.6875 0.932432
54 00A 0.686047 0.883117
55 OOB 0.682353 0.931507
56 5SV 0.682353 0.848101
57 8QN 0.682353 0.931507
58 3OD 0.681818 0.945205
59 BIS 0.681818 0.933333
60 ALF ADP 0.674699 0.87013
61 ADP ALF 0.674699 0.87013
62 AMO 0.674419 0.932432
63 4AD 0.674419 0.92
64 PAJ 0.674419 0.884615
65 GAP 0.670732 0.893333
66 MAP 0.670588 0.945946
67 AHX 0.666667 0.896104
68 VO4 ADP 0.666667 0.931507
69 DLL 0.666667 0.931507
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LMS 0.653333 0.82716
75 LAD 0.651685 0.860759
76 WAQ 0.651685 0.883117
77 B5V 0.651685 0.906667
78 PR8 0.651685 0.85
79 ITT 0.65 0.943662
80 7D4 0.65 0.905405
81 G5P 0.648936 0.921053
82 XYA 0.647059 0.84507
83 ADN 0.647059 0.84507
84 RAB 0.647059 0.84507
85 1ZZ 0.644444 0.839506
86 ME8 0.644444 0.839506
87 FYA 0.644444 0.905405
88 NB8 0.644444 0.896104
89 TXA 0.644444 0.932432
90 6AD 0.642857 0.909091
91 ADP BMA 0.640449 0.918919
92 G3A 0.638298 0.921053
93 DAL AMP 0.632184 0.905405
94 AFH 0.631579 0.884615
95 9SN 0.630435 0.871795
96 9ZA 0.625 0.907895
97 DQV 0.625 0.958333
98 9ZD 0.625 0.907895
99 GTA 0.625 0.886076
100 YAP 0.623656 0.894737
101 B5M 0.623656 0.894737
102 FA5 0.623656 0.906667
103 B5Y 0.623656 0.894737
104 UP5 0.622449 0.92
105 HFD 0.619048 0.945946
106 XAH 0.617021 0.839506
107 AV2 0.616279 0.917808
108 AOC 0.615385 0.821918
109 48N 0.612245 0.896104
110 4UV 0.610526 0.894737
111 6V0 0.606061 0.896104
112 NAI 0.606061 0.907895
113 DND 0.606061 0.932432
114 NAX 0.606061 0.873418
115 NXX 0.606061 0.932432
116 TXD 0.606061 0.907895
117 5N5 0.605634 0.819444
118 5AS 0.604938 0.77907
119 A4P 0.60396 0.843373
120 DAT 0.60241 0.905405
121 A2R 0.602273 0.985915
122 TXE 0.6 0.907895
123 OMR 0.6 0.851852
124 4UU 0.597938 0.894737
125 GA7 0.597938 0.906667
126 A A 0.597826 0.944444
127 A4D 0.597222 0.819444
128 5CD 0.597222 0.805556
129 AP0 0.594059 0.896104
130 4TC 0.594059 0.896104
131 A3P 0.592593 0.971429
132 T5A 0.592233 0.841463
133 139 0.592233 0.873418
134 7D5 0.592105 0.878378
135 ATP A A A 0.589474 0.930556
136 LAQ 0.585859 0.839506
137 MYR AMP 0.585106 0.817073
138 F2R 0.580952 0.864198
139 YLP 0.58 0.819277
140 UPA 0.578431 0.907895
141 7DD 0.578313 0.985714
142 3AM 0.576923 0.929577
143 ADJ 0.576923 0.851852
144 COD 0.575472 0.811765
145 NAD 0.575472 0.931507
146 3AT 0.574713 0.971831
147 JB6 0.574468 0.883117
148 4UW 0.574257 0.860759
149 EP4 0.573333 0.753247
150 A2P 0.573171 0.957143
151 CNA 0.571429 0.932432
152 TYM 0.568627 0.906667
153 PPS 0.568182 0.873418
154 DTA 0.565789 0.786667
155 M2T 0.565789 0.734177
156 AR6 AR6 0.565657 0.917808
157 A3D 0.564815 0.918919
158 80F 0.564815 0.841463
159 3DH 0.564103 0.773333
160 G5A 0.563218 0.77907
161 YLB 0.563107 0.819277
162 YLC 0.563107 0.839506
163 AMP DBH 0.561224 0.893333
164 TYR AMP 0.561224 0.87013
165 MTA 0.558442 0.773333
166 DTP 0.556818 0.905405
167 AHZ 0.554455 0.817073
168 NA7 0.553191 0.958904
169 IOT 0.552381 0.831325
170 ZAS 0.55 0.766234
171 7MD 0.55 0.8625
172 ARG AMP 0.55 0.829268
173 IMO 0.548781 0.929577
174 YLA 0.54717 0.819277
175 NAE 0.544643 0.894737
176 TAD 0.544554 0.884615
177 A5A 0.544444 0.807229
178 2AM 0.544304 0.943662
179 TSB 0.543478 0.819277
180 6RE 0.54321 0.759494
181 AYB 0.542056 0.809524
182 NAQ 0.539823 0.871795
183 V3L 0.539326 0.971831
184 SSA 0.538462 0.8
185 AF3 ADP 3PG 0.538462 0.8375
186 ZID 0.535088 0.918919
187 LPA AMP 0.533981 0.817073
188 52H 0.532609 0.77907
189 VMS 0.532609 0.788235
190 54H 0.532609 0.788235
191 BTX 0.53211 0.841463
192 A3N 0.53012 0.786667
193 J7C 0.53012 0.769231
194 5X8 0.528736 0.763158
195 BT5 0.527273 0.831325
196 8X1 0.526882 0.752809
197 5CA 0.526882 0.8
198 53H 0.526882 0.77907
199 ARU 0.526316 0.860759
200 EAD 0.525862 0.873418
201 RGT 0.525253 0.958904
202 OVE 0.52439 0.905405
203 S4M 0.52381 0.666667
204 7DT 0.522727 0.985714
205 GDP 0.522222 0.92
206 DDS 0.522222 0.878378
207 AVV 0.521277 0.896104
208 NDE 0.521008 0.932432
209 7MC 0.518868 0.841463
210 DSH 0.518072 0.725
211 MAO 0.517647 0.759036
212 NSS 0.515789 0.8
213 DSZ 0.515789 0.8
214 LSS 0.515789 0.761364
215 P5A 0.515464 0.744444
216 DZD 0.513514 0.884615
217 NVA LMS 0.510417 0.752809
218 9K8 0.510204 0.714286
219 12D 0.509615 0.785714
220 M24 0.508772 0.85
221 YLY 0.508772 0.809524
222 P1H 0.508333 0.851852
223 5AD 0.506849 0.746479
224 GJV 0.505882 0.75
225 LEU LMS 0.505155 0.752809
226 AMP NAD 0.504505 0.905405
227 4TA 0.504505 0.807229
228 G A A A 0.504505 0.871795
229 NAJ PZO 0.504425 0.848101
230 GSU 0.5 0.77907
231 128 0.5 0.776471
232 KAA 0.5 0.752809
233 71V 0.5 0.907895
234 A3G 0.5 0.8
235 NDC 0.5 0.871795
236 7D7 0.5 0.743243
237 N0B 0.495726 0.819277
238 NJP 0.495495 0.945946
239 ODP 0.495495 0.909091
240 2SA 0.494624 0.932432
241 6C6 0.494505 0.881579
242 SFG 0.494382 0.75
243 0WD 0.491071 0.921053
244 YSA 0.490196 0.77907
245 PO4 PO4 A A A A PO4 0.489796 0.902778
246 SAM 0.48913 0.690476
247 6IA 0.48913 0.8375
248 A7D 0.488636 0.776316
249 6FA 0.488 0.841463
250 FB0 0.487805 0.804598
251 NAJ PYZ 0.487179 0.807229
252 A5D 0.483516 0.786667
253 IDP 0.483516 0.918919
254 SA8 0.483516 0.707317
255 PGS 0.483146 0.883117
256 MHZ 0.483146 0.697674
257 DA 0.482353 0.878378
258 D5M 0.482353 0.878378
259 NEC 0.482353 0.746667
260 NIA 0.481928 0.822785
261 Y3J 0.480519 0.726027
262 8PZ 0.480392 0.8
263 FAD 0.480315 0.851852
264 FAS 0.480315 0.851852
265 FDA 0.48 0.833333
266 N6P 0.479592 0.915493
267 GGZ 0.479167 0.825
268 U A 0.478261 0.907895
269 SAH 0.478261 0.74359
270 SAI 0.478261 0.734177
271 A G 0.477876 0.883117
272 NPW 0.477477 0.886076
273 NDP 0.477477 0.921053
274 AAM 0.476744 0.971429
275 C2R 0.47561 0.90411
276 AMZ 0.47561 0.916667
277 A A A 0.474747 0.905405
278 GTP 0.473684 0.92
279 U A G G 0.473684 0.883117
280 SMM 0.473684 0.686047
281 NZQ 0.473214 0.909091
282 TXP 0.473214 0.921053
283 A3S 0.47191 0.810811
284 SFD 0.46875 0.734043
285 AIR 0.468354 0.901408
286 AAT 0.468085 0.707317
287 EEM 0.468085 0.690476
288 J7V 0.466667 0.833333
289 Z5A 0.466667 0.77907
290 7C5 0.466667 0.818182
291 62F 0.465649 0.8625
292 HDV 0.463158 0.893333
293 FAY 0.462121 0.8625
294 A3T 0.461538 0.821918
295 ETB 0.461538 0.833333
296 DCA 0.461538 0.823529
297 A6D 0.46 0.722892
298 A U 0.459459 0.87013
299 GEK 0.459184 0.7375
300 6K6 0.459184 0.930556
301 RFL 0.458647 0.821429
302 NAP 0.458333 0.945205
303 S7M 0.458333 0.690476
304 4YB 0.457944 0.761364
305 WSA 0.454545 0.788235
306 TAP 0.454545 0.907895
307 FNK 0.454545 0.804598
308 COA 0.453782 0.823529
309 0T1 0.453782 0.823529
310 101 0.453488 0.878378
311 XNP 0.452174 0.873418
312 NA0 0.45082 0.932432
313 7RP 0.448276 0.928571
314 GP3 0.446809 0.921053
315 TM1 0.446602 0.77381
316 APU 0.446429 0.894737
317 PUA 0.445378 0.884615
318 V1N 0.443396 0.917808
319 7RA 0.443182 0.957747
320 COS 0.442623 0.804598
321 AMX 0.442623 0.833333
322 30N 0.442623 0.752688
323 CAO 0.442623 0.795455
324 QQY 0.44186 0.815789
325 ACK 0.44186 0.861111
326 649 0.441441 0.744444
327 0UM 0.44 0.698795
328 NHD 0.439655 0.905405
329 CMX 0.439024 0.823529
330 SCO 0.439024 0.823529
331 GCP 0.438776 0.896104
332 8BR 0.438202 0.906667
333 GNH 0.4375 0.907895
334 8Q2 0.4375 0.772727
335 3AD 0.4375 0.805556
336 NVA 2AD 0.43617 0.759494
337 62X 0.435644 0.666667
338 FCX 0.435484 0.795455
339 ACO 0.435484 0.795455
340 FAM 0.435484 0.804598
341 9JJ 0.434783 0.8625
342 GNP 0.434343 0.896104
343 9GM 0.434343 0.896104
344 NMX 0.433071 0.76087
345 MGP 0.43299 0.884615
346 26A 0.432099 0.763158
347 HAX 0.432 0.804598
348 K15 0.431373 0.682353
349 DG1 0.430894 0.921053
350 1DG 0.430894 0.921053
351 QQX 0.430233 0.805195
352 2VA 0.430108 0.8
353 S8M 0.43 0.759494
354 2MC 0.429688 0.769231
355 6G0 0.428571 0.884615
356 P5F 0.428571 0.823529
357 FYN 0.428571 0.823529
358 3KK 0.428571 0.804598
359 A C A C 0.428571 0.848101
360 7L1 0.427419 0.795455
361 FAI 0.426966 0.916667
362 RMB 0.426966 0.873239
363 AS 0.426966 0.833333
364 1RB 0.425287 0.885714
365 CA6 0.425197 0.729167
366 SOP 0.425197 0.804598
367 OXK 0.425197 0.804598
368 MCD 0.425197 0.804598
369 COK 0.425197 0.804598
370 G1R 0.424242 0.907895
371 SXZ 0.423077 0.710843
372 CC5 0.423077 0.816901
373 F2N 0.422535 0.813953
374 EO7 0.422222 0.788235
375 ANZ 0.422018 0.8
376 1VU 0.421875 0.795455
377 CMC 0.421875 0.804598
378 CO6 0.421875 0.804598
379 ZDA 0.421053 0.864865
380 GKE 0.420561 0.884615
381 GDC 0.420561 0.884615
382 GDD 0.420561 0.884615
383 NFD 0.420168 0.883117
384 GSP 0.42 0.873418
385 D3Y 0.42 0.789474
386 MC4 0.419847 0.76087
387 3D1 0.419753 0.773333
388 3L1 0.419753 0.773333
389 FA9 0.41958 0.864198
390 5GP 0.419355 0.906667
391 G 0.419355 0.906667
392 KB1 0.419048 0.698795
393 CAJ 0.418605 0.804598
394 SCD 0.418605 0.823529
395 CMP 0.417582 0.901408
396 2BA 0.417582 0.915493
397 SO8 0.416667 0.789474
398 VRT 0.416667 0.769231
399 N01 0.416667 0.905405
400 IVC 0.415385 0.813953
401 1HE 0.415385 0.786517
402 A1S 0.415385 0.804598
403 BCO 0.415385 0.804598
404 3HC 0.415385 0.813953
405 MLC 0.415385 0.804598
406 NMN AMP PO4 0.415254 0.87013
407 2FA 0.414634 0.813333
408 MGO 0.414141 0.860759
409 3NZ 0.413462 0.782051
410 COO 0.412214 0.804598
411 MCA 0.412214 0.795455
412 YE1 0.412214 0.813953
413 CAA 0.412214 0.813953
414 GAV 0.411765 0.884615
415 PRT 0.411215 0.931507
416 JLN 0.411111 0.890411
417 P2P 0.411111 0.902778
418 ZZB 0.410256 0.77381
419 SP1 0.409091 0.842105
420 RP1 0.409091 0.842105
421 2CP 0.409091 0.795455
422 SCA 0.409091 0.804598
423 103 0.409091 0.837838
424 PAX 0.408 0.829268
425 FAD NBT 0.407143 0.75
426 COW 0.406015 0.795455
427 3CP 0.406015 0.804598
428 IRC 0.406015 0.813953
429 BYC 0.406015 0.804598
430 CA8 0.406015 0.729167
431 1GZ 0.406015 0.795455
432 COF 0.406015 0.786517
433 HGG 0.406015 0.804598
434 2KQ 0.406015 0.786517
435 G2P 0.405941 0.884615
436 SLU 0.404959 0.770115
437 U A C C 0.404959 0.858974
438 RBZ 0.404494 0.849315
439 1CZ 0.404412 0.795455
440 FAQ 0.402985 0.804598
441 BCA 0.402985 0.795455
442 4CA 0.402985 0.795455
443 MTP 0.402439 0.730769
444 8OD 0.402062 0.945205
445 CO7 0.401515 0.804598
446 GRA 0.4 0.804598
447 G2R 0.4 0.884615
448 ENQ 0.4 0.916667
449 CNV FAD 0.4 0.8
450 GMV 0.4 0.896104
451 HXC 0.4 0.786517
452 HF7 0.4 0.893333
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4U0S; Ligand: ADP; Similar sites found with APoc: 176
This union binding pocket(no: 1) in the query (biounit: 4u0s.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 5TVI MYR None
2 2VWA PTY None
3 2ZFZ ARG None
4 4F4S EFO None
5 3QLM PLM None
6 1YUC EPH 0.784314
7 3O01 DXC 1.62338
8 4OHU NAD 1.7301
9 4OHU 2TK 1.7301
10 1ZPD CIT 1.74419
11 3ITJ CIT 1.77515
12 2UXI G50 1.90476
13 2J5V PCA 2.03488
14 3B9Z CO2 2.03488
15 1QZR CDX 2.03488
16 1QZR ANP 2.03488
17 5U97 PIT 2.03488
18 2R0N TGC 2.03488
19 2OG2 MLI 2.03488
20 1Y7I SAL 2.23881
21 3VET TOY 2.32558
22 5IUY BOG 2.32558
23 1OXO IK2 2.32558
24 4WGF HX2 2.43902
25 2E2R 2OH 2.45902
26 4ONC 40B 2.46479
27 3WCA FPS 2.61628
28 1FO3 KIF 2.61628
29 5JBE MAL 2.61628
30 4DO1 ANN 2.61628
31 1X9D SMD 2.61628
32 1XMY ROL 2.61628
33 3V66 D3A 2.64706
34 1IZC PYR 2.65487
35 1GEG GLC 2.73438
36 1YOK P6L 2.73438
37 5K7K 6RJ 2.90698
38 5IM3 DTP 2.90698
39 1B4N GUA 2.90698
40 2YYJ 4HP 2.90698
41 2IHU TP9 2.90698
42 4Z7X 3CX 2.94118
43 2UW1 GVM 2.95858
44 2C6Q NDP 3.1339
45 3TL1 JRO 3.14465
46 1DL5 SAH 3.15457
47 3WYJ H78 3.16206
48 4F06 PHB 3.19767
49 4LY9 1YY 3.19767
50 4LY9 S6P 3.19767
51 3K5I AIR 3.19767
52 5LIA 6XN 3.19767
53 5LX9 OLB 3.25733
54 1R6N 434 3.31754
55 4MRP GSH 3.48837
56 3AQT RCO 3.48837
57 5KD8 TNR 3.48837
58 1Q7E MET 3.48837
59 2BO4 FLC 3.48837
60 3KFC 61X 3.55731
61 4LA7 A1O 3.62694
62 5JNN 6LM 3.68421
63 5CX6 CDP 3.77907
64 4H6Q TFB 3.84615
65 5M37 9SZ 3.91304
66 5M36 9SZ 3.93013
67 6BR8 PGV 3.96825
68 4OIV XX9 3.9823
69 3TDC 0EU 4.06977
70 1NU4 MLA 4.12371
71 4G86 BNT 4.22535
72 3OJI PYV 4.2328
73 2YIV YIV 4.26829
74 5JO1 6LM 4.32432
75 1EM6 CP4 4.36047
76 4WBD CIT 4.36047
77 1ZXM ANP 4.36047
78 1Q19 SSC 4.36047
79 5EK3 5PK 4.36047
80 4K4D HFQ 4.37956
81 4WVO 3UZ 4.41989
82 4Q9M FPP 4.47154
83 6A0S NDP 4.51807
84 5OLK DTP 4.65116
85 1H74 ADP 4.72973
86 4UMJ BFQ 4.72973
87 1H74 ILE 4.72973
88 5DRB 5FJ 4.811
89 1ZED PNP 4.94186
90 5UR6 8KM 4.97238
91 5C9J DAO 5.05051
92 2GBB CIT 5.12821
93 4O4Z N2O 5.19481
94 2BCG GER 5.23256
95 4PGK Y69 5.32787
96 2CIX CEJ 5.35117
97 3CF6 SP1 5.38922
98 3OID TCL 5.52326
99 1XPJ TLA 5.55556
100 4TV1 36M 5.57769
101 5W7B MYR 5.67376
102 5ZZ6 NAD 5.76923
103 4RYV ZEA 5.80645
104 4COL DTP 5.81395
105 1YKJ FAD 5.81395
106 4JLS 3ZE 5.92105
107 3KO0 TFP 5.94059
108 4DOL PLM 5.99078
109 4W97 UCA 6
110 1LVK MNT BEF 6.10465
111 3PDB PMP 6.10465
112 5URY PAM 6.16438
113 4I90 CHT 6.27063
114 6BVK EAV 6.58683
115 6BVM EBV 6.58683
116 6BVL EBY 6.58683
117 6BVJ EAS 6.58683
118 6BVI EC4 6.58683
119 2VBQ BSJ 6.66667
120 3RV5 DXC 6.74157
121 6ESN BWE 6.74157
122 5TIV A3P 7.11462
123 2AX9 BHM 7.42188
124 5KDX GAL TNR 7.55814
125 5H06 MAL 7.55814
126 1BWO LPC 7.77778
127 4URX FK1 8.10811
128 1JBW TMF 8.13953
129 1JBW ACQ 8.13953
130 4NTO 1PW 8.21256
131 1M48 FRG 8.27068
132 3KDJ A8S 8.41584
133 2XXP DSL 8.43023
134 1SBR VIB 8.5
135 6CB2 OLC 8.53242
136 1D5Z ACE ALC ARG ALA ODA SER LEU NH2 8.83978
137 5UGW GSH 9.14286
138 5ZKC 3C0 9.30233
139 2AWN ADP 9.30233
140 5NM7 GLY 9.3985
141 3N7S 3N7 9.56522
142 5C1M OLC 10.1351
143 4M7V RAR 10.2857
144 5UWA 8ND 10.3448
145 1EU1 GLC 10.4651
146 2ZCQ B65 10.5802
147 2O66 FLC 11.1111
148 5MWE TCE 11.4286
149 5CHR 4NC 11.6788
150 4KVL PLM 12.7907
151 2V5E SCR 13
152 4OGQ 2WD 13.5135
153 4OGQ 7PH 13.5135
154 4OGQ 1O2 13.5135
155 3KP6 SAL 13.9073
156 2HZL PYR 13.9535
157 4BNU 9KQ 14.8256
158 1MT1 AG2 15.3846
159 4DJA FAD 15.8301
160 4DJA DLZ 15.8301
161 3JRS A8S 15.8654
162 6MVU K4V 16.5698
163 1M2Z BOG 16.7315
164 2Y69 CHD 18.9189
165 5Z84 CHD 19.1781
166 5W97 CHD 19.1781
167 5ZCO CHD 19.1781
168 5ZCO TGL 19.1781
169 2DYR TGL 19.1781
170 5Z84 TGL 19.1781
171 2DYS TGL 19.1781
172 6C0B MLI 19.2308
173 4ZGM 32M 19.3548
174 5UC1 486 19.8198
175 5NNT DPV 29.7297
176 3SE5 ANP 47.561
Pocket No.: 2; Query (leader) PDB : 4U0S; Ligand: ADP; Similar sites found with APoc: 34
This union binding pocket(no: 2) in the query (biounit: 4u0s.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 4WG0 CHD None
2 1RRC ADP 1.3289
3 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 1.36054
4 4PVV HO4 2.16049
5 4GBD MCF 2.32558
6 5G3N X28 2.3622
7 4BFW ZVW 2.51572
8 4XU6 TDA 2.85714
9 2Z7I 742 3.23529
10 2CBZ ATP 3.37553
11 1QPB PYM 3.73002
12 4U82 FPS 3.90625
13 5V4R MGT 4.32099
14 5W6Y TRP 4.74684
15 4MAF ADX 4.94186
16 1G6H ADP 5.05837
17 5CSM TRP 5.07812
18 2YB9 HA0 5.23256
19 1XQP 8HG 5.46875
20 6H5E ANP 5.57769
21 6GMN F4E 5.76923
22 1W78 PD8 5.81395
23 6MPT C30 5.94406
24 2VTD LKM 6.10465
25 5C2H 4PX 6.39535
26 1T0S BML 6.97674
27 3FUR Z12 6.98529
28 3AD8 PYC 7.67327
29 3AD8 FAD 7.67327
30 3WQM B29 7.97342
31 2OWZ CIT 9.33735
32 5LJ0 6XX 10.7692
33 1NHZ 486 15.3571
34 4C12 ADP 25.8721
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