Receptor
PDB id Resolution Class Description Source Keywords
4UWJ 1.7 Å EC: 2.3.1.97 CRYSTAL STRUCTURE OF ASPERGILLUS FUMIGATUS N-MYRISTOYL TRANSFERASE IN COMPLEX WITH MYRISTOYL COA AND A CAPPED P YRAZOLE SULPHONAMIDE LIGAND ASPERGILLUS FUMIGATUS TRANSFERASE DRUG DISCOVERY
Ref.: LEAD OPTIMIZATION OF A PYRAZOLE SULFONAMIDE SERIES TRYPANOSOMA BRUCEI N-MYRISTOYLTRANSFERASE INHIBITOR IDENTIFICATION AND EVALUATION OF CNS PENETRANT COMP POTENTIAL TREATMENTS FOR STAGE 2 HUMAN AFRICAN TRYPANOSOMIASIS. J.MED.CHEM. V
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MYA A:1494;
Valid;
none;
submit data
977.89 C35 H62 N7 O17 P3 S CCCCC...
7L5 A:1493;
Valid;
none;
submit data
509.44 C21 H28 Cl2 F2 N4 O2 S Cc1c(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4UWJ 1.7 Å EC: 2.3.1.97 CRYSTAL STRUCTURE OF ASPERGILLUS FUMIGATUS N-MYRISTOYL TRANSFERASE IN COMPLEX WITH MYRISTOYL COA AND A CAPPED P YRAZOLE SULPHONAMIDE LIGAND ASPERGILLUS FUMIGATUS TRANSFERASE DRUG DISCOVERY
Ref.: LEAD OPTIMIZATION OF A PYRAZOLE SULFONAMIDE SERIES TRYPANOSOMA BRUCEI N-MYRISTOYLTRANSFERASE INHIBITOR IDENTIFICATION AND EVALUATION OF CNS PENETRANT COMP POTENTIAL TREATMENTS FOR STAGE 2 HUMAN AFRICAN TRYPANOSOMIASIS. J.MED.CHEM. V
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 4QBJ - 2XQ C25 H23 F3 N2 O3 Cc1c(oc2c1....
2 4UWJ - 7L5 C21 H28 Cl2 F2 N4 O2 S Cc1c(c(n(n....
3 4UWI - MYA C35 H62 N7 O17 P3 S CCCCCCCCCC....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 7 families.
1 4QBJ - 2XQ C25 H23 F3 N2 O3 Cc1c(oc2c1....
2 4UWJ - 7L5 C21 H28 Cl2 F2 N4 O2 S Cc1c(c(n(n....
3 4UWI - MYA C35 H62 N7 O17 P3 S CCCCCCCCCC....
50% Homology Family (52)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4CAF Ki = 75 nM 370 C21 H23 N5 O2 S Cc1c(c(n[n....
2 4B10 - NHW C36 H64 N7 O17 P3 S CCCCCCCCCC....
3 4BBH Ki = 0.08 uM YBN C22 H23 N O4 S COc1cccc(c....
4 2YND Ki = 32 nM 646 C21 H24 Cl2 N6 O2 S Cc1c(c(n(n....
5 5G22 Ki = 0.1 uM YN4 C25 H27 N5 O3 S CCOC(=O)c1....
6 4B11 ic50 = 2.3 uM 7I1 C26 H26 N2 O3 Cc1c2c(ccc....
7 4CAE Ki = 18 nM 3F3 C23 H23 N3 O3 S COc1cccc(c....
8 4B12 ic50 = 10.2 uM C23 C23 H25 N O3 Cc1c2c(ccc....
9 5G1Z Ki = 4.7 uM U53 C16 H16 N2 O3 S CCOC(=O)c1....
10 2YNE Ki = 2.7 nM YNE C22 H25 N5 O2 S Cc1c(c(n(n....
11 4B13 ic50 = 2 uM X25 C23 H23 N3 O3 Cc1c2c(ccc....
12 4A95 ic50 = 2.9 uM 9MT C18 H22 N2 O S CCCCc1c(nc....
13 4B14 ic50 = 0.6 uM 4XB C23 H25 N O5 Cc1c2c(ccc....
14 4C68 - EN5 C27 H53 N5 O4 C1CCC(CC1)....
15 5AG5 - DLR C17 H15 N3 O S c1ccc(cc1)....
16 4CYO Ki = 1.6 nM UEK C29 H30 Cl2 F N3 O3 c1cc(ccc1C....
17 2WSA Kd = 1 nM 646 C21 H24 Cl2 N6 O2 S Cc1c(c(n(n....
18 4A2Z - MYA C35 H62 N7 O17 P3 S CCCCCCCCCC....
19 4UCP Kd = 200 uM 9X3 C13 H20 N2 O CNCc1cccc(....
20 4A33 - PS8 C21 H24 Cl2 N6 O2 S Cc1c(c(n(n....
21 4CYP - A62 C21 H23 Cl2 N O3 c1cc(ccc1C....
22 4UCM Kd = 180 uM X6W C12 H15 N3 CNCc1cc(nn....
23 5G21 - YN4 C25 H27 N5 O3 S CCOC(=O)c1....
24 4CYQ Ki = 59 nM YAU C29 H29 Cl2 F N2 O4 c1cc(ccc1C....
25 4CGP - MYA C35 H62 N7 O17 P3 S CCCCCCCCCC....
26 2WUU ic50 = 68.7 nM NHW C36 H64 N7 O17 P3 S CCCCCCCCCC....
27 5AG6 - 5PE C16 H16 N2 O3 S COc1cc(ccc....
28 4CGL ic50 = 0.031 uM A6K C21 H24 Cl2 N2 O2 c1cc(ccc1C....
29 5AGE - M9M C23 H31 N3 O3 Cc1cc(no1)....
30 5A27 Ki = 0.02 uM TUT C21 H24 Cl N3 O3 [H]/N=C(Cc....
31 4A32 - MYA C35 H62 N7 O17 P3 S CCCCCCCCCC....
32 4C7H - COA C21 H36 N7 O16 P3 S CC(C)(CO[P....
33 4UCN - JRB C10 H15 N3 c1ccc(c(c1....
34 4C7I - JJ1 C27 H52 N4 O5 C1CCC(CC1)....
35 4CGN ic50 = 0.55 uM 7AH C21 H22 F N3 O c1cc(ccc1C....
36 5AG4 - MYA C35 H62 N7 O17 P3 S CCCCCCCCCC....
37 5G20 - QBY C23 H24 N2 O3 S CCSc1c2cc(....
38 4A30 - MYA C35 H62 N7 O17 P3 S CCCCCCCCCC....
39 4CGM ic50 = 1.02 uM CWZ C27 H28 N4 S c1cc(cc(c1....
40 4A31 - MYA C35 H62 N7 O17 P3 S CCCCCCCCCC....
41 5A28 Ki = 0.01 uM TUQ C20 H24 Cl N5 O2 Cc1c(c(n(n....
42 4CGO ic50 = 0.299 uM 6KV C17 H24 N6 S CN1CCC(CC1....
43 4CYN Ki = 1406 nM A6M C21 H24 Cl2 N2 O2 c1cc(ccc1C....
44 4C2X - NHW C36 H64 N7 O17 P3 S CCCCCCCCCC....
45 4QBJ - 2XQ C25 H23 F3 N2 O3 Cc1c(oc2c1....
46 4UWJ - 7L5 C21 H28 Cl2 F2 N4 O2 S Cc1c(c(n(n....
47 4UWI - MYA C35 H62 N7 O17 P3 S CCCCCCCCCC....
48 1IIC - MYA C35 H62 N7 O17 P3 S CCCCCCCCCC....
49 1IID - NHM C36 H64 N7 O17 P3 S CCCCCCCCCC....
50 1IYK Ki = 0.25 uM MIM C33 H52 N6 O4 Cc1nccn1CC....
51 4C2Y - MYA C35 H62 N7 O17 P3 S CCCCCCCCCC....
52 4C2Z ic50 = 17 nM 646 C21 H24 Cl2 N6 O2 S Cc1c(c(n(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: MYA; Similar ligands found: 133
No: Ligand ECFP6 Tc MDL keys Tc
1 DCC 1 1
2 ST9 1 1
3 5F9 1 1
4 MFK 1 1
5 UCC 1 1
6 MYA 1 1
7 CO8 0.992126 1
8 HXC 0.945736 1
9 BCO 0.877863 0.977528
10 YNC 0.876812 0.945055
11 HDC 0.862319 1
12 GRA 0.859259 0.955556
13 1HE 0.849624 0.956044
14 1VU 0.848485 0.988764
15 SCA 0.837037 0.955556
16 IVC 0.835821 0.966292
17 3HC 0.835821 0.966292
18 MRS 0.829787 1
19 MRR 0.829787 1
20 CS8 0.828571 0.988889
21 UOQ 0.822695 0.977778
22 NHM 0.822695 0.977778
23 NHW 0.822695 0.977778
24 MLC 0.822222 0.955556
25 0ET 0.821429 0.977778
26 8Z2 0.818182 0.988889
27 ACO 0.818182 0.988764
28 HGG 0.817518 0.955556
29 CAA 0.816176 0.966292
30 3KK 0.80597 0.977528
31 CAO 0.80303 0.923913
32 COS 0.80303 0.934066
33 OXK 0.8 0.955556
34 FAQ 0.798561 0.955556
35 CO6 0.794118 0.977528
36 0T1 0.793893 0.955056
37 2MC 0.788321 0.935484
38 TGC 0.787234 0.945055
39 FYN 0.779412 0.955056
40 DCA 0.778626 0.955056
41 MCA 0.776978 0.966667
42 COO 0.776978 0.955556
43 SOP 0.773723 0.955556
44 COK 0.773723 0.934066
45 MC4 0.771429 0.925532
46 COA MYR 0.770833 0.966667
47 PLM COA 0.770833 0.966667
48 COA PLM 0.770833 0.966667
49 CMC 0.768116 0.934066
50 COA 0.766917 0.955056
51 COW 0.765957 0.945055
52 IRC 0.765957 0.966292
53 1GZ 0.765957 0.945055
54 BYC 0.765957 0.955556
55 30N 0.762963 0.876289
56 AMX 0.762963 0.94382
57 CAJ 0.76259 0.955556
58 BCA 0.760563 0.945055
59 CMX 0.757353 0.933333
60 A1S 0.757143 0.955556
61 2NE 0.756944 0.934783
62 COF 0.753521 0.913979
63 3CP 0.753521 0.934066
64 ETB 0.75188 0.922222
65 2CP 0.746479 0.945055
66 HAX 0.746377 0.913043
67 1CZ 0.744828 0.945055
68 SCO 0.744526 0.933333
69 NMX 0.742857 0.865979
70 2KQ 0.741259 0.977778
71 FAM 0.73913 0.913043
72 FCX 0.73913 0.903226
73 SCD 0.737589 0.933333
74 4CA 0.736111 0.923913
75 MCD 0.735714 0.955556
76 CA6 0.735714 0.887755
77 WCA 0.72973 0.934783
78 4KX 0.724832 0.924731
79 CCQ 0.721088 0.935484
80 CIC 0.721088 0.934066
81 0FQ 0.716216 0.934066
82 4CO 0.716216 0.923913
83 DAK 0.715232 0.924731
84 UCA 0.7125 0.977778
85 01A 0.711409 0.894737
86 HFQ 0.708609 0.913979
87 1CV 0.706667 0.955556
88 CA8 0.705479 0.868687
89 YE1 0.703448 0.923077
90 1HA 0.703226 0.934783
91 NHQ 0.701299 0.944444
92 S0N 0.697987 0.913043
93 01K 0.687898 0.955556
94 CA3 0.675 0.934066
95 COT 0.672956 0.934066
96 CA5 0.664634 0.894737
97 CO7 0.657718 0.955556
98 93P 0.650602 0.923913
99 93M 0.641176 0.923913
100 COD 0.624114 0.94382
101 5TW 0.605556 0.93617
102 4BN 0.605556 0.93617
103 HMG 0.601266 0.923077
104 JBT 0.597826 0.916667
105 OXT 0.585635 0.93617
106 BSJ 0.548913 0.904255
107 191 0.524691 0.887755
108 PAP 0.515385 0.775281
109 RFC 0.49711 0.956044
110 SFC 0.49711 0.956044
111 ACE SER ASP ALY THR NH2 COA 0.484694 0.913043
112 PPS 0.481481 0.721649
113 A3P 0.469231 0.764045
114 1ZZ 0.468531 0.866667
115 0WD 0.467949 0.755319
116 OMR 0.45098 0.877778
117 S2N 0.443662 0.688889
118 PTJ 0.428571 0.833333
119 PUA 0.426829 0.784946
120 MYR AMP 0.425676 0.846154
121 3AM 0.423077 0.752809
122 MDE 0.419689 0.978022
123 A22 0.416667 0.777778
124 NA7 0.414966 0.820225
125 5SV 0.413793 0.853933
126 YLB 0.411392 0.888889
127 PAJ 0.410959 0.844444
128 ATR 0.407143 0.764045
129 WAQ 0.402685 0.822222
130 YLP 0.401274 0.888889
131 A2D 0.4 0.766667
132 3OD 0.4 0.788889
133 A2R 0.4 0.777778
Ligand no: 2; Ligand: 7L5; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 7L5 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4UWJ; Ligand: MYA; Similar sites found: 141
This union binding pocket(no: 1) in the query (biounit: 4uwj.bio1) has 61 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2BOS GLA GAL 0.002043 0.49303 None
2 4BG4 ADP 0.0109 0.4367 1.1236
3 4PPF FLC 0.002881 0.50385 1.42857
4 4OFJ HIS 0.04064 0.42383 1.4742
5 4KBA 1QM 0.02183 0.42793 1.51057
6 2ZPA ACO 0.0001232 0.51508 1.9656
7 5MRH Q9Z 0.01396 0.44994 1.9656
8 4CJN QNZ 0.03438 0.43455 1.9656
9 1TV5 N8E 0.03663 0.43077 1.9656
10 4MRP GSH 0.03143 0.43378 2.2113
11 1Y7P RIP 0.006593 0.43012 2.24215
12 3H55 GLA 0.04306 0.41548 2.25
13 4O9S 2RY 0.01752 0.40744 2.32558
14 1VPD TLA 0.02969 0.43176 2.34114
15 2WPW ACO 0.001616 0.48249 2.35988
16 2WPX ACO 0.001355 0.48208 2.35988
17 3A16 PXO 0.02906 0.42124 2.41287
18 3FW9 SLX 0.01957 0.42087 2.42424
19 5KJW 53C 0.01598 0.45403 2.457
20 2NSX IFM 0.04267 0.4157 2.457
21 1JI0 ATP 0.02804 0.437 2.5
22 5H2U 1N1 0.02404 0.42247 2.62172
23 5D48 L96 0.02486 0.40065 2.63158
24 2G30 ALA ALA PHE 0.0001916 0.502 2.71318
25 2BOY BHO 0.03145 0.42288 2.75591
26 5KO1 6UY 0.01426 0.43414 2.82686
27 3KIF GDL 0.04538 0.42488 2.83019
28 2ZFN ACO 0.01064 0.41962 2.9484
29 2FT0 ACO 0.02065 0.42587 2.97872
30 5LN8 GAL 0.0492 0.43476 3.05344
31 4K30 NLG 0.00518 0.47397 3.125
32 4MAF ADX 0.04733 0.40441 3.21782
33 4RYV ZEA 0.04847 0.41598 3.22581
34 2CM4 RCL 0.007773 0.43432 3.33333
35 4LED XXR 0.02529 0.41065 3.35821
36 2JDC CAO 0.0003926 0.47373 3.42466
37 1QY1 PRZ 0.03888 0.40093 3.44828
38 4WVW SLT 0.0117 0.4342 3.47222
39 2VDF OCT 0.003883 0.45068 3.55731
40 4AVB ACO 0.0006506 0.47423 3.6036
41 5CHR 4NC 0.01341 0.45665 3.64964
42 4YVN EBS 0.008512 0.46801 3.6855
43 2CBZ ATP 0.02463 0.43542 3.79747
44 4OTH DRN 0.03424 0.40359 3.81232
45 3ZJ0 ACO 0.001263 0.46128 3.8835
46 1N71 COA 0.0009744 0.48092 3.88889
47 3P2H NOO 0.00653 0.44787 3.9801
48 4H6U ACO 0.006004 0.43965 4
49 5W8E SXZ 0.0002271 0.46808 4.0724
50 5W8E ADE 0.0002718 0.46791 4.0724
51 2B4B COA 0.001054 0.47927 4.09357
52 4WOE ADP 0.02045 0.4454 4.1769
53 1BOB ACO 0.00002767 0.54044 4.375
54 2D6M LBT 0.03094 0.41761 4.40252
55 4FFG LBS 0.01374 0.45978 4.4226
56 2JIG PD2 0.03156 0.43004 4.46429
57 1OPB RET 0.01588 0.43175 4.47761
58 3I7V ATP 0.02216 0.42842 4.47761
59 4XBT FLC 0.04504 0.41129 4.51613
60 1QFT HSM 0.04707 0.40732 4.57143
61 1OGX EQU 0.02442 0.42536 4.58015
62 5C3R HMU 0.04365 0.40621 4.66472
63 5C3R AKG 0.04365 0.40621 4.66472
64 4NSQ COA 0.0009879 0.48894 4.6683
65 5GVR LMR 0.008287 0.47277 4.70085
66 1BO4 COA 0.0000291 0.59153 4.7619
67 5VRH OLB 0.02207 0.44557 4.914
68 1MFD GLA MMA ABE 0.01282 0.44006 5.02283
69 1DZK PRZ 0.01383 0.43483 5.09554
70 4J8T DOG 0.02374 0.42275 5.10949
71 5L2R MLA 0.02799 0.43338 5.15971
72 3UW5 MAA CHG PRO 0DQ 0.04664 0.42568 5.17241
73 4ZS4 ATP 0.03209 0.4102 5.21173
74 4NS0 PIO 0.01839 0.43533 5.26316
75 5FUI APY 0.005648 0.45418 5.30303
76 3C8F MT2 0.03402 0.4152 5.30612
77 1XK5 TPG 0.04373 0.42137 5.39216
78 5AIG VPR 0.001341 0.50662 5.6
79 1GP6 SIN 0.02822 0.40041 5.61798
80 1GP6 DH2 0.02822 0.40041 5.61798
81 2CNT COA 0.0000456 0.53052 5.625
82 4U0W 16G 0.04106 0.40756 5.69106
83 4MJ0 SIA SIA 0.04322 0.42647 5.81818
84 4UA3 COA 0.0001995 0.5141 6.18557
85 5FPX GLY SER SER HIS HIS HIS HIS HIS 0.04691 0.40195 6.19469
86 4DSU BZI 0.007101 0.47558 6.34921
87 5OO5 UUA 0.006366 0.45209 6.45161
88 1FK5 OLA 0.01473 0.41839 6.45161
89 3KP6 SAL 0.01738 0.44797 6.62252
90 3B9Q MLI 0.04718 0.41284 6.62252
91 2NLR BGC BGC G2F SHG 0.04221 0.41279 6.83761
92 3RGA LSB 0.009608 0.44294 7.06714
93 4K55 H6P 0.02675 0.42493 7.25806
94 3H7J PPY 0.01503 0.43644 7.40741
95 4UTW RFW 0.01046 0.44469 7.42358
96 3B6R ADP 0.004152 0.46157 7.61155
97 5K04 COA 0.001853 0.46035 7.61671
98 4U9W COA 0.0000881 0.51324 7.72947
99 5H86 BCO 0.00006 0.50865 7.7381
100 5OCA 9QZ 0.003402 0.50368 7.93651
101 2E27 AB0 0.0153 0.4397 7.93651
102 5D1R 56S 0.03932 0.41763 7.94979
103 1JJ7 ADP 0.03544 0.43381 8.84615
104 1QSM ACO 0.00002557 0.53293 9.21053
105 2ZW5 COA 0.0006211 0.48242 9.30233
106 1WWZ ACO 0.000189 0.48732 9.43396
107 4B5P ACO 0.001298 0.45447 9.5
108 5F6U 5VK 0.001179 0.51975 9.55414
109 2VWA PTY 0.03806 0.43384 9.90099
110 1CM0 COA 0.002202 0.47999 11.3095
111 3SHZ 5CO 0.01801 0.43969 11.5274
112 2Z5Y HRM 0.01985 0.44137 11.5479
113 5V4R MGT 0.04131 0.43754 11.7284
114 5XLY C2E 0.01708 0.42688 12.0301
115 3KFF XBT 0.01962 0.44594 12.3457
116 3KFF ZBT 0.01962 0.44594 12.3457
117 1PUA COA 0.0002198 0.51671 12.8834
118 1QSR ACO 0.00005561 0.52222 12.963
119 1QSN COA 0.0003138 0.50913 12.963
120 1Q2D COA 0.0009121 0.49067 12.963
121 5FU3 BGC BGC BGC 0.02167 0.44421 13.2075
122 3T50 FMN 0.04242 0.40414 13.2812
123 1N5S ADL 0.01364 0.43513 13.3929
124 3SXN COA 0.0000439 0.54072 13.5135
125 1NCQ W11 0.03175 0.41043 13.5593
126 3T4L ZEA 0.01054 0.43742 14.0741
127 4QC6 30N 0.00144 0.46544 14.5251
128 2HKA C3S 0.006701 0.44384 14.6154
129 2PZE ATP 0.04522 0.42452 14.8472
130 5FVJ ACO 0.00005569 0.51395 15.6627
131 1BHX ASP PHE GLU GLU ILE 0.003092 0.48144 16.6667
132 1GT4 UNA 0.03127 0.41656 16.9811
133 2HZQ STR 0.0487 0.42206 17.8161
134 1EB1 ASP TYR GLU PRO ILE PRO GLU GLU ALA PHE 0.0241 0.4291 18.5185
135 4XT2 43L 0.03343 0.40165 18.8034
136 4AG9 COA 0.0003999 0.52972 19.3939
137 4AG9 16G 0.008172 0.45846 19.3939
138 1EPB REA 0.0207 0.42582 19.5122
139 5H9Q TD2 0.01156 0.42326 20
140 4MTI 2DX 0.04643 0.42415 20.8696
141 4PSW COA 0.0007482 0.49956 21.0526
Pocket No.: 2; Query (leader) PDB : 4UWJ; Ligand: 7L5; Similar sites found: 141
This union binding pocket(no: 2) in the query (biounit: 4uwj.bio1) has 61 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2BOS GLA GAL 0.002043 0.49303 None
2 4BG4 ADP 0.0109 0.4367 1.1236
3 4PPF FLC 0.002881 0.50385 1.42857
4 4OFJ HIS 0.04064 0.42383 1.4742
5 4KBA 1QM 0.02183 0.42793 1.51057
6 2ZPA ACO 0.0001232 0.51508 1.9656
7 5MRH Q9Z 0.01396 0.44994 1.9656
8 4CJN QNZ 0.03438 0.43455 1.9656
9 1TV5 N8E 0.03663 0.43077 1.9656
10 4MRP GSH 0.03143 0.43378 2.2113
11 1Y7P RIP 0.006593 0.43012 2.24215
12 3H55 GLA 0.04306 0.41548 2.25
13 4O9S 2RY 0.01752 0.40744 2.32558
14 1VPD TLA 0.02969 0.43176 2.34114
15 2WPW ACO 0.001616 0.48249 2.35988
16 2WPX ACO 0.001355 0.48208 2.35988
17 3A16 PXO 0.02906 0.42124 2.41287
18 3FW9 SLX 0.01957 0.42087 2.42424
19 5KJW 53C 0.01598 0.45403 2.457
20 2NSX IFM 0.04267 0.4157 2.457
21 1JI0 ATP 0.02804 0.437 2.5
22 5H2U 1N1 0.02404 0.42247 2.62172
23 5D48 L96 0.02486 0.40065 2.63158
24 2G30 ALA ALA PHE 0.0001916 0.502 2.71318
25 2BOY BHO 0.03145 0.42288 2.75591
26 5KO1 6UY 0.01426 0.43414 2.82686
27 3KIF GDL 0.04538 0.42488 2.83019
28 2ZFN ACO 0.01064 0.41962 2.9484
29 2FT0 ACO 0.02065 0.42587 2.97872
30 5LN8 GAL 0.0492 0.43476 3.05344
31 4K30 NLG 0.00518 0.47397 3.125
32 4MAF ADX 0.04733 0.40441 3.21782
33 4RYV ZEA 0.04847 0.41598 3.22581
34 2CM4 RCL 0.007773 0.43432 3.33333
35 4LED XXR 0.02529 0.41065 3.35821
36 2JDC CAO 0.0003926 0.47373 3.42466
37 1QY1 PRZ 0.03888 0.40093 3.44828
38 4WVW SLT 0.0117 0.4342 3.47222
39 2VDF OCT 0.003883 0.45068 3.55731
40 4AVB ACO 0.0006506 0.47423 3.6036
41 5CHR 4NC 0.01341 0.45665 3.64964
42 4YVN EBS 0.008512 0.46801 3.6855
43 2CBZ ATP 0.02463 0.43542 3.79747
44 4OTH DRN 0.03424 0.40359 3.81232
45 3ZJ0 ACO 0.001263 0.46128 3.8835
46 1N71 COA 0.0009744 0.48092 3.88889
47 3P2H NOO 0.00653 0.44787 3.9801
48 4H6U ACO 0.006004 0.43965 4
49 5W8E SXZ 0.0002271 0.46808 4.0724
50 5W8E ADE 0.0002718 0.46791 4.0724
51 2B4B COA 0.001054 0.47927 4.09357
52 4WOE ADP 0.02045 0.4454 4.1769
53 1BOB ACO 0.00002767 0.54044 4.375
54 2D6M LBT 0.03094 0.41761 4.40252
55 4FFG LBS 0.01374 0.45978 4.4226
56 2JIG PD2 0.03156 0.43004 4.46429
57 1OPB RET 0.01588 0.43175 4.47761
58 3I7V ATP 0.02216 0.42842 4.47761
59 4XBT FLC 0.04504 0.41129 4.51613
60 1QFT HSM 0.04707 0.40732 4.57143
61 1OGX EQU 0.02442 0.42536 4.58015
62 5C3R HMU 0.04365 0.40621 4.66472
63 5C3R AKG 0.04365 0.40621 4.66472
64 4NSQ COA 0.0009879 0.48894 4.6683
65 5GVR LMR 0.008287 0.47277 4.70085
66 1BO4 COA 0.0000291 0.59153 4.7619
67 5VRH OLB 0.02207 0.44557 4.914
68 1MFD GLA MMA ABE 0.01282 0.44006 5.02283
69 1DZK PRZ 0.01383 0.43483 5.09554
70 4J8T DOG 0.02374 0.42275 5.10949
71 5L2R MLA 0.02799 0.43338 5.15971
72 3UW5 MAA CHG PRO 0DQ 0.04664 0.42568 5.17241
73 4ZS4 ATP 0.03209 0.4102 5.21173
74 4NS0 PIO 0.01839 0.43533 5.26316
75 5FUI APY 0.005648 0.45418 5.30303
76 3C8F MT2 0.03402 0.4152 5.30612
77 1XK5 TPG 0.04373 0.42137 5.39216
78 5AIG VPR 0.001341 0.50662 5.6
79 1GP6 SIN 0.02822 0.40041 5.61798
80 1GP6 DH2 0.02822 0.40041 5.61798
81 2CNT COA 0.0000456 0.53052 5.625
82 4U0W 16G 0.04106 0.40756 5.69106
83 4MJ0 SIA SIA 0.04322 0.42647 5.81818
84 4UA3 COA 0.0001995 0.5141 6.18557
85 5FPX GLY SER SER HIS HIS HIS HIS HIS 0.04691 0.40195 6.19469
86 4DSU BZI 0.007101 0.47558 6.34921
87 5OO5 UUA 0.006366 0.45209 6.45161
88 1FK5 OLA 0.01473 0.41839 6.45161
89 3KP6 SAL 0.01738 0.44797 6.62252
90 3B9Q MLI 0.04718 0.41284 6.62252
91 2NLR BGC BGC G2F SHG 0.04221 0.41279 6.83761
92 3RGA LSB 0.009608 0.44294 7.06714
93 4K55 H6P 0.02675 0.42493 7.25806
94 3H7J PPY 0.01503 0.43644 7.40741
95 4UTW RFW 0.01046 0.44469 7.42358
96 3B6R ADP 0.004152 0.46157 7.61155
97 5K04 COA 0.001853 0.46035 7.61671
98 4U9W COA 0.0000881 0.51324 7.72947
99 5H86 BCO 0.00006 0.50865 7.7381
100 5OCA 9QZ 0.003402 0.50368 7.93651
101 2E27 AB0 0.0153 0.4397 7.93651
102 5D1R 56S 0.03932 0.41763 7.94979
103 1JJ7 ADP 0.03544 0.43381 8.84615
104 1QSM ACO 0.00002557 0.53293 9.21053
105 2ZW5 COA 0.0006211 0.48242 9.30233
106 1WWZ ACO 0.000189 0.48732 9.43396
107 4B5P ACO 0.001298 0.45447 9.5
108 5F6U 5VK 0.001179 0.51975 9.55414
109 2VWA PTY 0.03806 0.43384 9.90099
110 1CM0 COA 0.002202 0.47999 11.3095
111 3SHZ 5CO 0.01801 0.43969 11.5274
112 2Z5Y HRM 0.01985 0.44137 11.5479
113 5V4R MGT 0.04131 0.43754 11.7284
114 5XLY C2E 0.01708 0.42688 12.0301
115 3KFF XBT 0.01962 0.44594 12.3457
116 3KFF ZBT 0.01962 0.44594 12.3457
117 1PUA COA 0.0002198 0.51671 12.8834
118 1QSR ACO 0.00005561 0.52222 12.963
119 1QSN COA 0.0003138 0.50913 12.963
120 1Q2D COA 0.0009121 0.49067 12.963
121 5FU3 BGC BGC BGC 0.02167 0.44421 13.2075
122 3T50 FMN 0.04242 0.40414 13.2812
123 1N5S ADL 0.01364 0.43513 13.3929
124 3SXN COA 0.0000439 0.54072 13.5135
125 1NCQ W11 0.03175 0.41043 13.5593
126 3T4L ZEA 0.01054 0.43742 14.0741
127 4QC6 30N 0.00144 0.46544 14.5251
128 2HKA C3S 0.006701 0.44384 14.6154
129 2PZE ATP 0.04522 0.42452 14.8472
130 5FVJ ACO 0.00005569 0.51395 15.6627
131 1BHX ASP PHE GLU GLU ILE 0.003092 0.48144 16.6667
132 1GT4 UNA 0.03127 0.41656 16.9811
133 2HZQ STR 0.0487 0.42206 17.8161
134 1EB1 ASP TYR GLU PRO ILE PRO GLU GLU ALA PHE 0.0241 0.4291 18.5185
135 4XT2 43L 0.03343 0.40165 18.8034
136 4AG9 COA 0.0003999 0.52972 19.3939
137 4AG9 16G 0.008172 0.45846 19.3939
138 1EPB REA 0.0207 0.42582 19.5122
139 5H9Q TD2 0.01156 0.42326 20
140 4MTI 2DX 0.04643 0.42415 20.8696
141 4PSW COA 0.0007482 0.49956 21.0526
Feedback