-->
Receptor
PDB id Resolution Class Description Source Keywords
4WG0 1.82 Å NON-ENZYME: TRANSCRIPT_TRANSLATE CRYSTAL STRUCTURE OF A TRIDECAMERIC SUPERHELIX HOMO SAPIENS TIF2 CO-ACTIVATOR PEPTIDE ARCIMBOLDO MOLECULAR REPLACEMENTSUPERHELIX GLUCOCORTICOID RECEPTOR TRANSCRIPTION
Ref.: STRUCTURE OF A 13-FOLD SUPERHELIX (ALMOST) DETERMIN FIRST PRINCIPLES. IUCRJ V. 2 177 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CHD F:103;
E:104;
A:103;
J:103;
I:103;
H:103;
D:102;
C:102;
L:103;
G:103;
B:102;
M:103;
K:103;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
408.571 C24 H40 O5 C[C@H...
SO4 E:102;
E:101;
E:103;
D:101;
I:101;
H:102;
F:102;
G:101;
G:102;
A:102;
A:101;
I:102;
J:102;
M:102;
H:101;
C:101;
K:102;
M:101;
L:102;
F:101;
B:101;
K:101;
L:101;
J:101;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4WG0 1.82 Å NON-ENZYME: TRANSCRIPT_TRANSLATE CRYSTAL STRUCTURE OF A TRIDECAMERIC SUPERHELIX HOMO SAPIENS TIF2 CO-ACTIVATOR PEPTIDE ARCIMBOLDO MOLECULAR REPLACEMENTSUPERHELIX GLUCOCORTICOID RECEPTOR TRANSCRIPTION
Ref.: STRUCTURE OF A 13-FOLD SUPERHELIX (ALMOST) DETERMIN FIRST PRINCIPLES. IUCRJ V. 2 177 2015
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 291 families.
1 4WG0 - CHD C24 H40 O5 C[C@H](CCC....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 247 families.
1 4WG0 - CHD C24 H40 O5 C[C@H](CCC....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 4WG0 - CHD C24 H40 O5 C[C@H](CCC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: CHD; Similar ligands found: 6
No: Ligand ECFP6 Tc MDL keys Tc
1 CHD 1 1
2 GCH 0.785714 0.714286
3 DXC 0.609195 1
4 JN3 0.6 1
5 4OA 0.478261 0.972222
6 CHO 0.474747 0.714286
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4WG0; Ligand: CHD; Similar sites found with APoc: 439
This union binding pocket(no: 1) in the query (biounit: 4wg0.bio1) has 7 residues
No: Leader PDB Ligand Sequence Similarity
1 1TMX HGX None
2 5WRE 7TL None
3 2JBZ COA None
4 5N9T 8QQ None
5 4TMK T5A None
6 4E70 N7I None
7 3BQD DAY None
8 6G9I CXX None
9 4HIA FMN None
10 5JFL NAD None
11 2Z6D FMN None
12 6HH6 A3R None
13 3SHZ 5CO None
14 1OUK 084 None
15 3G08 FEE None
16 2JC9 ADN None
17 3RUG DB6 None
18 5GPG RAP None
19 3BJC WAN None
20 2AX9 BHM None
21 4ZBR DIF None
22 5NTP 98E None
23 1XM4 PIL None
24 4ZBR NPS None
25 2QZZ EMF None
26 2QZZ NAP None
27 4ASE AV9 None
28 3GWT 066 None
29 5G3N X28 None
30 2OFV 242 None
31 4O4K 2PK None
32 2XXP DSL None
33 3GWL FAD None
34 1PG4 PRX None
35 1PG4 COA None
36 3W54 RNB None
37 3LLI FAD None
38 3T50 FMN None
39 1XMU ROF None
40 5NTW 98N None
41 5MT9 SRO None
42 3V49 PK0 None
43 5WL1 D3D None
44 5WL1 CUY None
45 5OWC AYZ None
46 6B04 C6J None
47 2R40 20E None
48 2Z6C FMN None
49 4EES FMN None
50 3T58 FAD None
51 5KAU RHQ None
52 4MGB XDH None
53 2E9L PLM None
54 2E9L BGC None
55 2C9E PID None
56 3ET1 ET1 None
57 4WUJ FMN None
58 2A1L PCW None
59 1T27 PCW None
60 5UC1 486 None
61 3MBG FAD None
62 4V1T ADP None
63 4BQS ADP None
64 4BQS K2Q None
65 5EHR 5OD None
66 1SR7 MOF None
67 3D72 FAD None
68 1E1M FAD None
69 1E1M NAP None
70 2XN3 ID8 None
71 4OAS 2SW None
72 1OQC FAD None
73 3RET SAL None
74 4U0I 0LI None
75 2D4V NAD None
76 1NHZ 486 None
77 1NWW HPN None
78 4ZVI 4S4 None
79 6C1R EFD None
80 3GF4 U5P None
81 4OKS 2T9 None
82 3FAP ARD None
83 3RY9 1CA None
84 5U3B 7TD None
85 2J7T 274 None
86 1DMH LIO None
87 6G5J EM8 None
88 4MGD 27N None
89 2PR5 FMN None
90 5HCV 60R None
91 5CJF 520 None
92 1JR8 FAD None
93 1GNI OLA None
94 2CB8 MYA None
95 3EE4 MYR None
96 4IS0 1R4 None
97 4XNV BUR None
98 5LXT GDP None
99 5LXT 7AK None
100 2RKN LP3 None
101 1FK5 OLA None
102 5DY5 5GR None
103 5C9J STE None
104 5DCH 1YO None
105 5CSD ACD None
106 3RMK BML None
107 2VAP GDP None
108 3QCP FAD None
109 3SP6 IL2 None
110 2DYR PGV None
111 1XMY ROL None
112 1XRO LEU None
113 3UUD EST None
114 2XSU PIE None
115 6GG9 FMN None
116 4DRJ RAP None
117 3E7O 35F None
118 3GXO MQA None
119 2QCX PF1 None
120 6ET8 BWH None
121 5DX3 EST None
122 1W2Y DUN None
123 2ABS ACP None
124 5MWE TCE None
125 2OZ5 7XY None
126 3Q8G PEE None
127 3AI3 SOE None
128 5EW9 5VC None
129 5DJT FMN None
130 1LN1 DLP None
131 3QCJ NX4 None
132 1RQJ RIS None
133 2DYS PGV None
134 2WCJ M21 None
135 3HUJ AGH None
136 4H07 IPH None
137 2R75 01G None
138 2E3N 6CM None
139 2HFP NSI None
140 2AIB ERG None
141 4NKW PLO None
142 4XOQ F42 None
143 5ZCO PGV None
144 4KWD JF2 None
145 5OLK DTP None
146 4RC8 STE None
147 1D5Z ACE ALC ARG ALA ODA SER LEU NH2 None
148 3KPX CZH None
149 3R5Y F42 None
150 2BHW LUX None
151 2RH1 CLR None
152 2HFK E4H None
153 2V0U FMN None
154 2WPX ACO None
155 5WGQ EST None
156 6GBV FMN None
157 1S17 GNR None
158 5W7D PX8 None
159 3LOO B4P None
160 5ZBL AMP None
161 1BWO LPC None
162 5UWA 8ND None
163 4I67 G G G RPC None
164 5K13 6Q7 None
165 4FDV 0UK None
166 1P72 ADP None
167 1N8V BDD None
168 3ZS7 ATP None
169 4QGE 35O None
170 5IM3 DTP None
171 1DQE BOM None
172 5UV1 0FV None
173 3RET PYR None
174 3LDW IPE None
175 4INW 1EY None
176 1N9L FMN None
177 3VVY ET None
178 3D78 NBB None
179 1Z0S ATP None
180 2XN5 FUN None
181 1XON PIL None
182 3UUA 0CZ None
183 3WYJ H78 None
184 3B99 U51 None
185 1UUO ORO None
186 1UUO FMN None
187 1UUO BRF None
188 3KDU NKS None
189 3LDW ZOL None
190 5DKK FMN None
191 4DRI RAP None
192 4MG9 27K None
193 5DXG EST None
194 1T0S BML None
195 5WGD EST None
196 5Z84 CHD None
197 5NWI TYR PHE SER SEP ASN None
198 4J7Q B7N None
199 4X6F 3XU None
200 2FKW RG1 None
201 2I0G I0G None
202 5E7V M7E None
203 4TV1 36M None
204 1N1G BCP None
205 3F10 8HG None
206 4M73 SAH None
207 2PJL 047 None
208 5EFW FMN None
209 4JKV 1KS None
210 4P3H 25G None
211 5L92 C0R None
212 4LWU 20U None
213 1FP1 HCC None
214 5K52 OCD None
215 2Q2Y MKR None
216 2Q2Y ADP None
217 5LIA 6XN None
218 5LWY OLA None
219 1SUW NAP None
220 3SE5 ANP None
221 5Y72 DST None
222 2P54 735 None
223 5HYR EST None
224 5U98 VAL THR THR ASP ILE GLN VAL LYS VAL None
225 3P7N FMN None
226 3GQT UFO None
227 3R9C ECL None
228 1ZED PNP None
229 4WQ2 3SU None
230 5L92 MLA None
231 4M73 M72 None
232 1OPK MYR None
233 5B4B LP5 None
234 2EW5 Y12 None
235 3AHQ FAD None
236 2FV5 541 None
237 4ETZ C2E None
238 5ZM0 FAD None
239 5MWY YNU None
240 4MGA 27L None
241 4MG7 27H None
242 3KMZ EQO None
243 3A51 VDY None
244 1YYE 196 None
245 4QWT ACD None
246 3UWB BB2 None
247 5IXK 6EW None
248 5LOF 70R None
249 2QJY UQ2 None
250 5DXE EST None
251 2XCG XCG None
252 3G4G D71 None
253 2OBD PCW None
254 5LPA ATP None
255 5LPA 71R None
256 1PZO CBT None
257 1RDT 570 None
258 5N1Z 8GQ None
259 1M13 HYF None
260 4WT2 3UD None
261 2HU5 GLY PHE None
262 3O55 FAD None
263 5LX9 OLB None
264 4DXJ IPE None
265 2IDO TMP None
266 2C0U FAD NBT None
267 4I6G FAD None
268 5W97 CHD None
269 5TIV A3P None
270 5J6D 6H5 None
271 2GSQ GBI None
272 5Z1N PEF None
273 5OSW DIU None
274 5JKG 6LF None
275 3E8T UQ8 None
276 2QV6 GTP None
277 2PRG BRL None
278 1N46 PFA None
279 3SQP 3J8 None
280 5TBM 79A None
281 6B2M COA None
282 6BR8 6OU None
283 5YWX GSH None
284 5YWX 93C None
285 4XRQ 1B0 None
286 3F5O UOC COA None
287 2BCG GER None
288 4DJA FAD None
289 4DJA DLZ None
290 2VHW NAI None
291 3ZKI WZV None
292 1U3R 338 None
293 1UVC STE None
294 5UC9 MYR None
295 3CV9 VDX None
296 3G58 988 None
297 4UCC ZKW None
298 3G9E RO7 None
299 5TUX ECH None
300 5Z84 TGL None
301 5TWO 7MV None
302 6F68 GSH None
303 6F68 4EU None
304 5ECP ATP None
305 5ECP MET None
306 5ECP JAA None
307 5K53 STE None
308 3HP9 CF1 None
309 3IX9 MTX None
310 4JZX 476 None
311 5Y02 HBX None
312 1U3D FAD None
313 3UXH UXH None
314 3UXH FAD None
315 4UNR QZE None
316 5UI2 EQ3 None
317 6IIU A8X None
318 2IYA ZIO None
319 5ZCO PSC None
320 2DYS PEK None
321 5HGR 45D None
322 2IBZ UQ6 None
323 3M6P BB2 None
324 2VG1 FPP None
325 1JAY F42 None
326 1QV1 CZH None
327 4DXJ 0M9 None
328 4HBM 0Y7 None
329 1OFU GDP None
330 5VRH OLC None
331 1XX4 BAM None
332 4L1F COS None
333 5KLP IHP None
334 3GWN FAD None
335 5D9J 0N8 None
336 5ZCO CHD None
337 1JF0 CZH None
338 3IIS PID None
339 6GL8 F3Q None
340 4UDB CV7 None
341 4TWP AXI None
342 4OGQ BCR None
343 1IYK MYA None
344 5N69 2OW None
345 1BUC CAA None
346 3KJD 78P None
347 5DUF G7A None
348 3EBL GA4 None
349 1M5B BN1 None
350 5JZI LYS LEU VAL ALA LEU GLY ILE ASN ALA VAL None
351 3VRV YSD None
352 2QZT PLM None
353 6D59 FVJ None
354 4E90 7RG None
355 2VBQ BSJ None
356 2WKQ FMN None
357 6A5Y 9CR None
358 4LH7 NMN None
359 4RHP PEF None
360 5ZCO TGL None
361 3NHT U46 None
362 4OKZ 3E9 None
363 1RV1 IMZ None
364 3EUT DCR None
365 1OW4 2AN None
366 4ITH RCM None
367 3L1N PLM None
368 3FAL REA None
369 3ND6 ATP None
370 3FAL LO2 None
371 5L7G 6QE None
372 2P1C GG3 None
373 2J07 FAD None
374 2J07 HDF None
375 4IBF 1D5 None
376 4KIB SAH None
377 5FPN KYD None
378 4DM8 REA None
379 3WUR O4B None
380 4ZBA GDS None
381 6BR9 6OU None
382 1V1A ADP None
383 4WGF HX2 None
384 6D55 FWA None
385 4BFW ZVW None
386 5SVV FMN None
387 6D5H FV7 None
388 2Q1H AS4 None
389 2O7B HC4 None
390 1QIN GIP None
391 2YJD YJD None
392 2DYS TGL None
393 2WAT COA None
394 1HBK MYR None
395 5IVX ARG GLY PRO GLY ARG ALA PHE VAL THR ILE None
396 5THQ NDP None
397 5IJJ I6P None
398 2C43 COA None
399 2RHQ GAX None
400 5KJK 6T1 None
401 5KJK SAM None
402 5Z84 PGV None
403 6BJ3 ILE PRO LEU THR GLU GLU ALA GLU LEU None
404 6BVI EC4 None
405 5MW4 5JU None
406 1W5F G2P None
407 1RKD RIB None
408 1RKD ADP None
409 1YKD CMP None
410 2HJ3 FAD None
411 4CRL C1I None
412 4LNU GTP None
413 6CB2 OLC None
414 1HBK COA None
415 3OTX AP5 None
416 1GP2 GDP None
417 4OMJ 2TX None
418 4MNS 2AX None
419 5GUE GGS None
420 1EBL COA None
421 6F70 GSH None
422 4ELG 52I None
423 3WQM B29 None
424 6BVL EBY None
425 6D56 FVM None
426 1MID LAP None
427 3KMR EQN None
428 5UXM TRP None
429 6BVJ EAS None
430 4ELG 52J None
431 4R38 RBF None
432 2YOO K2B 33.3333
433 4ASJ N6A 33.3333
434 5NM7 GLY 33.3333
435 3G5N PB2 33.3333
436 1POC GEL 33.3333
437 6FX0 E9T 46.6667
438 4GU5 FAD 46.6667
439 2HHP FLC 46.6667
Pocket No.: 2; Query (leader) PDB : 4WG0; Ligand: CHD; Similar sites found with APoc: 75
This union binding pocket(no: 2) in the query (biounit: 4wg0.bio1) has 7 residues
No: Leader PDB Ligand Sequence Similarity
1 3V66 D3A None
2 4AG8 AXI None
3 5G57 6M5 None
4 2ZSH GA3 None
5 2E9L OLA None
6 6C7D EOJ None
7 2X5W K2B None
8 4C2X NHW None
9 2WSA 646 None
10 2WSA MYA None
11 5BYK OAQ None
12 5BYK A3P None
13 1MHC FME TYR PHE ILE ASN ILE LEU THR LEU None
14 5N5U 7N8 None
15 3OZV FAD None
16 5EK3 5PK None
17 1LRI CLR None
18 4KP7 NAP None
19 3HAZ NAD None
20 3UNG ADP None
21 4J4H 1J1 None
22 3WHB DCC None
23 5LX9 OLA None
24 4OIV XX9 None
25 3PE2 E1B None
26 5LGA 6VH None
27 3T6E MQ9 None
28 1K7L 544 None
29 4PFT MAB None
30 5Z84 PSC None
31 1W96 S1A None
32 3I51 6PL None
33 3IS2 FAD None
34 1TV5 A26 None
35 1J54 TMP None
36 4KP7 1UQ None
37 5ZBK AMP None
38 4FAJ LEU VAL THR LEU VAL PHE VAL None
39 1Q1Y BB2 None
40 3NJQ NJQ None
41 2O4J VD4 None
42 5B25 4QJ None
43 2YLD CMO None
44 3HDY GDU None
45 3HDY FDA None
46 3TGE TGE None
47 3H78 BE2 None
48 2BW7 APC None
49 2DYS PSC None
50 3FSM 2NC None
51 3E7J NAG GCU NAG GCD None
52 4OGQ 1O2 None
53 5OPM DTP None
54 1QFT HSM None
55 1NJF AGS None
56 1AOE NDP None
57 1AOE GW3 None
58 3JRX S1A None
59 4NS3 NAD None
60 4PXQ UAP SGN IDS SGN IDS SGN None
61 2D5Z L35 None
62 1TIQ COA None
63 3VC1 GST None
64 4XB4 45D None
65 5Y02 MXN None
66 1HK8 DGT None
67 1V97 MTE None
68 2A3I C0R None
69 5C2H 4XU None
70 2DYR PSC None
71 5LWY OLB None
72 3QT6 2P0 None
73 3ZQE DXC None
74 2VL8 UDP None
75 2VL8 CTS None
Pocket No.: 3; Query (leader) PDB : 4WG0; Ligand: CHD; Similar sites found with APoc: 249
This union binding pocket(no: 3) in the query (biounit: 4wg0.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 5N1X 8HH None
2 5DEY 59T None
3 1NP7 FAD None
4 1QNF FAD None
5 4XVX P33 FDA None
6 5AE2 FYC None
7 5AE2 FAD None
8 2ZCQ B65 None
9 3F3E LEU None
10 2CNT COA None
11 2B96 ANN None
12 4J4H NAI None
13 1DNP FAD None
14 1Y75 NAG None
15 2QTR NXX None
16 6GMN F4E None
17 3H0A D30 None
18 2J4D FAD None
19 5U98 1KX None
20 1JNQ EGT None
21 3RV5 DXC None
22 5W7U GY8 None
23 1OLM VTQ None
24 4M4Q 21A None
25 2O3Z AI7 None
26 3FUR Z12 None
27 1BZL GCG None
28 3ZPG 5GP None
29 3CH6 311 None
30 3CH6 NAP None
31 5B0W 22B None
32 1VG0 GER None
33 1VR0 3SL None
34 1H12 XYS None
35 1H12 XYP None
36 4B6C B5U None
37 4XU6 TDA None
38 6G09 BXP None
39 3GKJ HC3 None
40 3PPM JG1 None
41 6C0B PAM None
42 2Q6B HR2 None
43 4CDN FAD None
44 1QO8 FAD None
45 6FS8 E4Z None
46 2BHW NEX None
47 2CDC XYS None
48 2NPA MMB None
49 3H2B SAH None
50 4G31 0WH None
51 3C88 ARG ARG GLY CYS NH2 None
52 5KBZ 3B2 None
53 3WCA FPS None
54 3O01 DXC None
55 2UUU PL3 None
56 2JLB UDM None
57 4F97 VDO None
58 4C2V YJA None
59 5HCY 60D None
60 2VZZ SCA None
61 5A89 FMN None
62 5A89 ADP None
63 5ZYN FAD None
64 3L9R L9R None
65 3KRO DST None
66 3KRO IPE None
67 1R5L VIV None
68 4ZW9 GLC None
69 4ZW9 BGC None
70 4COL DTP None
71 5N87 N66 None
72 5JPH COA None
73 5FH7 5XL None
74 1LVK MNT BEF None
75 1KPG 16A None
76 4JHG ZEA None
77 2DYR TGL None
78 1MDC PLM None
79 4IGH FMN None
80 4IGH 1EA None
81 4IGH ORO None
82 5O42 BGC None
83 5O42 9JW None
84 5O42 NAD None
85 3NT6 COA None
86 2OO8 RAJ None
87 5BVE 4VG None
88 6B5Q PPI CZS 2KY MLY 1XY None
89 6DQU GLY ILE ILE ASN THR LEU None
90 6BR8 PGV None
91 3NTD COA None
92 3SDV 911 None
93 6ESN BWE None
94 3OKA GDD None
95 5K7K 6RJ None
96 5UR1 YY9 None
97 2DYR PEK None
98 5GLN XYS None
99 5GLN XYP XYP XYP None
100 4R81 FMN None
101 5UGW GSH None
102 2BMR 3NT None
103 1BOB ACO None
104 3PFD FDA None
105 1N20 3AG None
106 4RW3 PLM None
107 2ALG DAO None
108 2ALG HP6 None
109 3U5S FAD None
110 1W0O DAN None
111 1N6B DMZ None
112 1DBT U5P None
113 4LOC BTN None
114 5W3Y IHP None
115 5ZCO PEK None
116 3OU2 SAH None
117 1DTL BEP None
118 1O7Q UDP None
119 5APK 76E None
120 1YRO UDP None
121 3OKP GDD None
122 5X40 ACP None
123 5W3X IHP None
124 6FE1 V14 None
125 3TJH SER PRO LEU ASP SER LEU TRP TRP ILE None
126 1Q5H DUD None
127 2QQC AG2 None
128 1TF9 PHI None
129 5MPT SAH None
130 1W4R TTP None
131 5E58 CPZ None
132 5HTX ADP None
133 4V3I ASP LEU THR ARG PRO None
134 5WPJ NDP None
135 2OCI TYC None
136 3NB0 G6P None
137 1BXK NAD None
138 5WIU AQD None
139 3RGA ILD None
140 1KPH 10A None
141 5HZ5 65X None
142 5V3Y 5V8 None
143 2FP2 TSA None
144 4AZP A9M None
145 4NB5 2JT None
146 2Z77 HE7 None
147 4KBS PX2 None
148 3GGO ENO None
149 3GGO NAI None
150 5EOB 5QQ None
151 5DLY 5D7 None
152 5DLY SAH None
153 5G5G MCN None
154 5GWE GWM None
155 2C3Q GTX None
156 4ITM ATP None
157 5MYD DUP None
158 4RZ3 ADP None
159 1TW4 CHD None
160 2O5L MNR None
161 6EOF ADP None
162 3HRD MCN None
163 1IZE IVA VAL VAL STA ALA STA None
164 3HY2 ATP None
165 2YCH ATP None
166 4BR5 ANP None
167 3CQD ATP None
168 4MRP GSH None
169 2QJY SMA None
170 5XJN 88L None
171 5OVL NAP None
172 2AEL SAZ None
173 2QM9 TDZ None
174 3IPQ 965 None
175 1O6U PLM None
176 6A5Y 9R0 None
177 3OLL EST None
178 2FYU FDN None
179 2NNQ T4B None
180 3D9F FAD None
181 4F97 GDP None
182 4FAI PBD None
183 5JFS 6K0 None
184 2XFH CL6 None
185 5B0I BOG None
186 3KB9 BTM None
187 2IV3 UDP None
188 4Q9M FPP None
189 4XVX P6G FDA None
190 1FA2 DOM None
191 5CJH 522 None
192 4MLN ODV None
193 5J6C FMN None
194 6BMM OLB None
195 3W68 VIV None
196 1RDT L79 None
197 1P1M MET None
198 3KYO LYS LEU PRO ALA GLN PHE TYR ILE LEU None
199 4G6I RS3 None
200 4G86 BNT None
201 4CZG QH3 None
202 1OPK P16 None
203 4CVZ TYR GLU LEU ASP GLU LYS PHE ASP ARG LEU None
204 3QKD HI0 None
205 3RDE OYP None
206 4O08 PO6 None
207 1LDN NAD None
208 1RL4 BRR None
209 3MTW M3R None
210 4A1O JLN None
211 1ELW GLY PRO THR ILE GLU GLU VAL ASP None
212 1N13 AG2 None
213 4A2B AGS None
214 2Z3U CRR None
215 1GQ2 NAP None
216 6CBN OZY None
217 1MT1 AG2 None
218 3R9V DXC None
219 1OGX EQU None
220 4WEY EG6 None
221 3PDT ADP None
222 3BF1 PAU None
223 3BF1 ADP None
224 5UFS 1TA None
225 6FK6 DOK None
226 2FXD DR7 None
227 3CYI ATP None
228 2JAP NDP None
229 4U63 FAD None
230 5MIL DUP None
231 1LOX RS7 None
232 1YHM AHD None
233 1HFE CYS None
234 1KZN CBN None
235 6MVU K4V None
236 4EWH T77 None
237 2QQD AG2 None
238 4CRZ ACO None
239 5EDL VIB None
240 2H7C COA None
241 1GV0 NAD None
242 5LS7 ACO None
243 1VLH PNS None
244 2RHO GSP None
245 3CXH SMA 4.10959
246 2BES RES 33.3333
247 2PFC PLM 33.3333
248 5TO8 7FM 46.6667
249 5N26 CPT 46.6667
Pocket No.: 4; Query (leader) PDB : 4WG0; Ligand: CHD; Similar sites found with APoc: 120
This union binding pocket(no: 4) in the query (biounit: 4wg0.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 5IKH 6BW None
2 3QLM PLM None
3 1PVN MZP None
4 6EQS BV8 None
5 1QNF HDF None
6 4NES UDP None
7 4CQE CQE None
8 4Q9M 2ZW None
9 1T57 FMN None
10 1S8G DAO None
11 2YNE NHW None
12 2YNE YNE None
13 1UDY FAD None
14 5DRB 5FJ None
15 4NAT ADP None
16 5KF6 FAD None
17 5KF6 TFB None
18 2C29 NAP None
19 2C29 DQH None
20 4KCF AKM None
21 5W8Q BU4 None
22 3X1M COA None
23 2FR6 CTN None
24 4WRI OKA None
25 3IVM ZPR None
26 6GBX S77 None
27 1ZSQ PIB None
28 4F7E 0SH None
29 3VHE 42Q None
30 3U3U EAH None
31 5HMY LNY None
32 4LSJ LSJ None
33 2J1P GRG None
34 4OGQ UMQ None
35 3S43 478 None
36 1KQP ADJ None
37 4QOM PYG None
38 4GV4 MEJ None
39 3O3O 2RH None
40 2R40 EPH None
41 3JRS A8S None
42 4PJT 2YQ None
43 2FR6 URI None
44 1ESM COA None
45 3WBG 2AN None
46 4BUY F37 None
47 2Z7I 742 None
48 2IBZ SMA None
49 4MYD 164 None
50 4F9U PBD None
51 4O1Z MXM None
52 5O0B 9FE None
53 2QE0 NAP None
54 3ZBQ GDP None
55 3NTA COA None
56 4MFL MFK None
57 1EZV SMA None
58 3EMY IVA VAL VAL STA ALA STA None
59 3JZB 4HY None
60 2F2H XTG None
61 1FO0 ILE ASN PHE ASP PHE ASN THR ILE None
62 1WBI BTN None
63 5X0J SEP None
64 5X0J AMP None
65 5WS9 ATP None
66 2P8U COA None
67 2QZX IVA VAL VAL STA ALA STA None
68 3T6E UQ9 None
69 5Z84 PEK None
70 2WZG UPG None
71 2QCD U5P None
72 1UU1 PMP HSA None
73 2RHO GDP None
74 2JG1 ANP None
75 4ZRB COA None
76 3RYC GTP None
77 4HKP TKW None
78 2W41 ADP None
79 6C0T EE4 None
80 3FON VAL ASN ASP ILE PHE GLU ALA ILE None
81 3HB5 E2B None
82 5EXW 7DT None
83 3ICS COA None
84 4JNE ATP None
85 4OAR 2S0 None
86 3HRD FAD None
87 5HZ9 5M8 None
88 4XTX 590 None
89 4J26 EST None
90 2F59 INI None
91 2AK3 AMP None
92 1XPK CAA None
93 6BQC LOP None
94 1Q2C COA None
95 4HA9 NDP None
96 2Z77 NCA None
97 3L41 LYS PRO SEP GLN GLU LEU None
98 1UI0 URA None
99 5Y6Q MCN None
100 5M3E APR None
101 4HMT FMN None
102 4HMT NNV None
103 6C7R EO4 None
104 2Y69 CHD None
105 3ABA FLI None
106 5XDT ZI7 None
107 9LDB NAD None
108 5JNN 6LM None
109 1GUZ NAD None
110 2NV4 SAM None
111 1A05 IPM None
112 2PX6 DH9 None
113 4U0S ADP None
114 2QWO ADP None
115 4BJ8 BTN None
116 5XJ8 NKO None
117 1X9D SMD None
118 3OA2 NAD None
119 3HKW IX6 40
120 2ZKJ ADP 46.6667
Pocket No.: 5; Query (leader) PDB : 4WG0; Ligand: CHD; Similar sites found with APoc: 50
This union binding pocket(no: 5) in the query (biounit: 4wg0.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 2IFB PLM None
2 1NJF ADP None
3 4CDN FO1 None
4 5FM0 WAQ None
5 1JQ9 PHE LEU SER TYR LYS None
6 3COW 52H None
7 4JWK CTN None
8 3QDJ ALA ALA GLY ILE GLY ILE LEU THR VAL None
9 4NJS G08 None
10 2GU8 796 None
11 3EYK EYK None
12 4ZOW CLM None
13 5ET3 60C None
14 5ZKC 3C0 None
15 3BGD PM6 None
16 4U82 FPS None
17 3T34 GDP None
18 1ZAP A70 None
19 4REF 3N0 None
20 2BIF BOG None
21 5NWD 9C8 None
22 1VPV PLM None
23 5MT9 ARG None
24 2X4T ASN LEU VAL PRW MET VAL ALA THR VAL None
25 2IMF TOM None
26 2IMF GSH None
27 3B6C SDN None
28 3HYW DCQ None
29 4KVL PLM None
30 4BVM VCA None
31 5OVK NDP None
32 1JJE BYS None
33 6BE0 IHP None
34 1LSH PLD None
35 3X01 AMP None
36 6B21 C9V None
37 4H6Q TFB None
38 4P42 PEE None
39 4BVM PLM None
40 1DQX BMP None
41 3G5D 1N1 None
42 2OQ2 A3P None
43 4V24 GYR None
44 6BMS PLM None
45 2D24 XYS XYS XYS XYS XYS None
46 2BVL GLC None
47 2BVL UDP None
48 3UG4 AHR 40
49 5FTW SAH 40
50 3CB2 GDP 40
Pocket No.: 6; Query (leader) PDB : 4WG0; Ligand: CHD; Similar sites found with APoc: 25
This union binding pocket(no: 6) in the query (biounit: 4wg0.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 4YV5 SVR None
2 2EV1 OLA None
3 1EWF PC1 None
4 2UUU FAD None
5 5LUN OGA None
6 5LUN ARG None
7 2GN4 UD1 None
8 1TKK ALA GLU None
9 3E3U NVC None
10 5K5M 68T None
11 3L9R L9Q None
12 1U8V FAD None
13 5J6A P46 None
14 4A2A ATP None
15 6DUB SAH None
16 4GBD MCF None
17 5JJR 68E None
18 3OV6 MK0 None
19 5H62 UDP None
20 2XTS MTE None
21 9LDT NAD None
22 1GHE ACO None
23 3D04 SAK None
24 5HGZ ACO None
25 6FK3 PPI None
Pocket No.: 7; Query (leader) PDB : 4WG0; Ligand: CHD; Similar sites found with APoc: 36
This union binding pocket(no: 7) in the query (biounit: 4wg0.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 3LSJ PLM COA None
2 3P5P A3C None
3 1UDY CS8 None
4 5HWO HMG None
5 2GMH UQ5 None
6 1OAA OAA None
7 3PB9 1BN None
8 5OJI ISN None
9 2C3W GLC GLC GLC GLC None
10 1PI5 SM2 None
11 1LBT T80 None
12 2Q4H AMP None
13 4Z5W TYS ILE TYS THR GLN None
14 2H8Z FMN None
15 2H8Z 8CM None
16 4IA6 EIC None
17 6ADI 9UO None
18 1XPK HMG None
19 5ND5 TPP None
20 1O7Q GAL NAG None
21 1XPM CAA None
22 1XPM HMG None
23 1SIV PSI None
24 4LZJ 22H None
25 4PIO SAH None
26 3ZO7 K6H None
27 4Q6R 30J None
28 3DSK T25 None
29 5KKB BMA NAG MAN MAN MAN MAN MAN MAN MAN None
30 5FKP 6UL None
31 1JXZ BCA None
32 1OGZ EQU None
33 2GBP BGC None
34 4EKQ NPO None
35 3FV3 IVA VAL VAL STA ALA STA None
36 2IGA XX3 46.6667
Pocket No.: 8; Query (leader) PDB : 4WG0; Ligand: CHD; Similar sites found with APoc: 14
This union binding pocket(no: 8) in the query (biounit: 4wg0.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 5C0C ARG GLN PHE GLY PRO ASP TRP ILE VAL ALA None
2 3R1V AZB None
3 5TDU PCR None
4 3D9F N6C None
5 1IID NHM None
6 5ODQ FAD None
7 4QBK 3NZ None
8 6C8T EQJ None
9 1COY FAD None
10 1F5V FMN None
11 4WNP 3RJ None
12 4NKT 2KH None
13 2WOE AR6 None
14 5K1F IMP None
Pocket No.: 9; Query (leader) PDB : 4WG0; Ligand: CHD; Similar sites found with APoc: 21
This union binding pocket(no: 9) in the query (biounit: 4wg0.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 1QZR ANP None
2 3QFJ LEU LEU PHE GLY PHE PRO VAL TYR VAL None
3 3SCM LGN None
4 2PHN GDP None
5 2APC UDM None
6 3N3T C2E None
7 5BNS 4VM None
8 4OGQ 2WA None
9 5XVH TLA None
10 6GIN IR2 None
11 4Q0A GLY HIS LYS ILE LEU HIS ARG LEU LEU GLN None
12 5CHR 4NC None
13 2GJ3 FAD None
14 2C9O ADP None
15 1EP2 FMN None
16 5XJ7 87O None
17 1KJM ALA GLN PHE SER ALA SER ALA SER ARG None
18 5TK8 7D5 None
19 3C9U ADP None
20 4XRZ SI6 None
21 1RJD SAM 40
Pocket No.: 10; Query (leader) PDB : 4WG0; Ligand: CHD; Similar sites found with APoc: 136
This union binding pocket(no: 10) in the query (biounit: 4wg0.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 2J8C U10 None
2 2J8C SPO None
3 4F4P 0SB None
4 1UBY DMA None
5 3VPH NAD None
6 1OWB NAD None
7 1LDM NAD None
8 3VPH OXM None
9 5MFI LYS ARG LYS ARG LYS ARG LYS ARG None
10 4OYA 1VE None
11 6CEP NAD None
12 3I6I NDP None
13 4F4S EFO None
14 6BR9 PGV None
15 2VCN ISZ None
16 6D28 NEC None
17 3ZCB ATP None
18 4CLI 5P8 None
19 1C9K 5GP None
20 4WN5 MVC None
21 3UYK 0CX None
22 1LEK GLU GLN TYR LYS PHE TYR SER VAL None
23 2OBD 2OB None
24 2BNE U5P None
25 4Q86 AMP None
26 5J32 IPM None
27 4PLT NAI None
28 3ER9 3AT None
29 2C78 PUL None
30 1L7P SEP None
31 4DOL PLM None
32 3KFC 61X None
33 1YQZ FAD None
34 2ZYI STE None
35 1ZGA HMK None
36 1ADO 13P None
37 4YRY FAD None
38 5TVA COA None
39 1P6D 3PC None
40 1Z83 AP5 None
41 2GTE VA None
42 1RQ2 CIT None
43 5AZC PGT None
44 1EE0 CAA None
45 1BGQ RDC None
46 4PGK Y69 None
47 5JF2 SF7 None
48 1DIG NAP None
49 1DIG L37 None
50 5OHJ 9VE None
51 3ICT COA None
52 4O6W ACE PRO LEU 2SO SER TPO NH2 None
53 4WO4 JLS None
54 2YPO PHE None
55 3WQT ANP None
56 5O22 C3R None
57 4DHY S41 None
58 1TV5 N8E None
59 4JK3 NAD None
60 3QVP FAD None
61 2OKL BB2 None
62 5CUQ NSC None
63 2WYA HMG None
64 3ZVS MLI None
65 4DOO DAO None
66 3ORF NAD None
67 2HFU MEV None
68 4EOX 0S5 None
69 1D1G NDP None
70 4RKS MEV None
71 2WME NAP None
72 3O9Z NAD None
73 4MG8 27J None
74 5FWA J7C None
75 4B9Q ATP None
76 4LBP 1WG None
77 1FO3 KIF None
78 4DR9 BB2 None
79 1NYT NAP None
80 2ZMF CMP None
81 5OVV ACE ILE GLU SER THR GLU ILE None
82 5WA0 MSS None
83 3RS8 APR None
84 5AG3 3EB None
85 2D5X L35 None