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Receptor
PDB id Resolution Class Description Source Keywords
4WGF 2.34 Å EC: 3.-.-.- YCAC FROM PSEUDOMONAS AERUGINOSA WITH HEXANE-2,5-DIOL AND CO ACRYLAMIDE PSEUDOMONAS AERUGINOSA CO-PURIFIED HYDROLASE PARALLEL BETA-SHEET CONTAMINANT.
Ref.: CRYSTAL STRUCTURE OF A HIDDEN PROTEIN, YCAC, A PUTA CYSTEINE HYDROLASE FROM PSEUDOMONAS AERUGINOSA, WIT WITHOUT AN ACRYLAMIDE ADDUCT. INT J MOL SCI V. 16 15971 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
HX2 A:305;
C:302;
B:302;
G:302;
F:302;
D:302;
H:302;
A:302;
 Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
 none;
none;
none;
none;
none;
none;
none;
none;
 submit data
118.174 C6 H14 O2 C[C@H...
CL F:303;
C:303;
D:303;
H:303;
A:303;
E:302;
B:303;
G:303;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
none;
none;
none;
 submit data
35.453 Cl [Cl-]
SO4 G:304;
F:304;
D:304;
E:303;
F:305;
H:304;
B:304;
C:304;
A:304;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
none;
none;
none;
none;
 submit data
96.063 O4 S [O-]S...
ROP E:301;
H:301;
G:301;
B:301;
A:301;
D:301;
C:301;
F:301;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
none;
none;
none;
 submit data
73.094 C3 H7 N O CCC(=...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4WGF 2.34 Å EC: 3.-.-.- YCAC FROM PSEUDOMONAS AERUGINOSA WITH HEXANE-2,5-DIOL AND CO ACRYLAMIDE PSEUDOMONAS AERUGINOSA CO-PURIFIED HYDROLASE PARALLEL BETA-SHEET CONTAMINANT.
Ref.: CRYSTAL STRUCTURE OF A HIDDEN PROTEIN, YCAC, A PUTA CYSTEINE HYDROLASE FROM PSEUDOMONAS AERUGINOSA, WIT WITHOUT AN ACRYLAMIDE ADDUCT. INT J MOL SCI V. 16 15971 2015
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 253 families.
1 4WGF - HX2 C6 H14 O2 C[C@H](CC[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 4WGF - HX2 C6 H14 O2 C[C@H](CC[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 173 families.
1 4WGF - HX2 C6 H14 O2 C[C@H](CC[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: HX2; Similar ligands found: 5
No: Ligand ECFP6 Tc MDL keys Tc
1 DYD 1 1
2 HX2 1 1
3 BU4 0.6 0.7
4 BU2 0.6 0.7
5 SBT 0.5 0.625
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4WGF; Ligand: HX2; Similar sites found with APoc: 278
This union binding pocket(no: 1) in the query (biounit: 4wgf.bio1) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 2ZKJ ADP None
2 1BGQ RDC None
3 4UNR QZE None
4 4POJ 2VP None
5 3BEJ MUF None
6 4M8E 29V None
7 3OKI OKI None
8 1P1C SAH None
9 3DCT 064 None
10 2CNT COA None
11 2WG9 OCA None
12 3RUU 37G None
13 5ICK FEZ None
14 4OAR 2S0 0.97561
15 1SR7 MOF 0.97561
16 2JG1 ANP 0.97561
17 3R5Y F42 1.36054
18 4XCL AGS 1.46341
19 5UC4 83S 1.46341
20 2AX9 BHM 1.46341
21 3K9U ACO 1.88679
22 4L1F COS 1.95122
23 3H4L ANP 1.95122
24 5HCV 60R 1.95122
25 3D9F N6C 1.95122
26 5B4B LP5 1.95122
27 3HLX PQQ 1.95122
28 4R5M NAP 1.95122
29 1BWO LPC 2.22222
30 1LL2 UPG 2.43902
31 3OZV FAD 2.43902
32 6C7D EOJ 2.43902
33 5ZM0 FAD 2.43902
34 1KIJ NOV 2.43902
35 5J6A P46 2.43902
36 5U3B 7TD 2.43902
37 4ZBR NPS 2.43902
38 4GU5 FAD 2.43902
39 3LDW ZOL 2.43902
40 1TL2 NDG 2.43902
41 4QOM PYG 2.43902
42 1ATL 0QI 2.47525
43 3R5W F42 2.67857
44 4BIX ADP 2.92683
45 3P3G UKW 2.92683
46 3P3G 3P3 2.92683
47 1MO9 FAD 2.92683
48 1MO9 KPC 2.92683
49 2WPF WPF 2.92683
50 2WPF FAD 2.92683
51 6BA2 7KM 2.92683
52 5L7G 6QE 2.92683
53 5MWY YNU 2.92683
54 3ZOK NAD 2.92683
55 3SJU NDP 2.92683
56 2Z7I 742 2.92683
57 5K7H IVC 2.92683
58 5TUX ECH 2.92683
59 3T58 FAD 2.92683
60 1M7G ADP 2.92683
61 3KCC CMP 2.92683
62 6A5Y 9CR 2.92683
63 3NZK C90 2.92683
64 1M7G ADX 2.92683
65 3IBH GSH 2.92683
66 4GFD 0YB 2.92683
67 4KOT CE3 3.08642
68 3WHB DCC 3.09278
69 2WTX UDP 3.41463
70 3KMZ EQO 3.41463
71 3G9E RO7 3.41463
72 6DIO NAD 3.41463
73 3FUR Z12 3.41463
74 2P4Y C03 3.41463
75 2WTX VDO 3.41463
76 5TWO 7MV 3.41463
77 4NE2 ADP 3.41463
78 3ET3 ET1 3.41463
79 4KVL PLM 3.41463
80 1RDT 570 3.41463
81 3B1M KRC 3.41463
82 2HFP NSI 3.41463
83 5HTX ADP 3.41463
84 2QV6 GTP 3.41463
85 2ZYI STE 3.41463
86 1FM9 570 3.41463
87 2PI8 NAG NAG NAG NAG NAG NAG 3.41463
88 2PRG BRL 3.41463
89 1M7Y PPG 3.41463
90 3BF1 PAU 3.41463
91 3GWN FAD 3.50877
92 2QZT PLM 3.6036
93 4DR9 BB2 3.64583
94 5AEW BNL 3.7234
95 3ZLR X0B 3.79747
96 3UWB BB2 3.8961
97 1ZXM ANP 3.90244
98 2X5W K2B 3.90244
99 4M52 M52 3.90244
100 5AE2 FAD 3.90244
101 5AE2 FYC 3.90244
102 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 3.90244
103 4PJT 2YQ 3.90244
104 3FAL LO2 3.90244
105 3FAL REA 3.90244
106 4M0R 644 3.90244
107 1LOR BMP 3.90244
108 6FX0 E9T 3.90244
109 3IPQ 965 3.90244
110 2HKJ RDC 3.90244
111 2ZGY GDP 3.90244
112 1X1Z BMP 3.90244
113 3ZCN ATP 3.90244
114 1DB1 VDX 3.90244
115 4GV4 MEJ 3.90244
116 6C28 WCA 4.30108
117 3JUQ AKD 4.32432
118 3JUQ AJD 4.32432
119 2O1V ADP 4.39024
120 4URL XAM 4.39024
121 3WYJ H78 4.39024
122 4I6G FAD 4.39024
123 4G2R H1L 4.39024
124 1XRO LEU 4.39024
125 4GCZ ADP 4.39024
126 1JAY F42 4.39024
127 2XCG XCG 4.39024
128 4XSU UDP 4.39024
129 5AB7 MLC 4.39024
130 6EJI UD2 4.87805
131 2Q1H AS4 4.87805
132 4P6X HCY 4.87805
133 3AYI FAD 4.87805
134 4DM8 REA 4.87805
135 5HGR 45D 4.87805
136 3RY9 1CA 4.87805
137 3RC1 TLO 4.87805
138 3EWK FAD 4.87805
139 1U1F 183 4.87805
140 2JHP GUN 4.87805
141 5G5W R8C 4.87805
142 4PL9 ADP 4.91803
143 2CJF RP4 5.09554
144 5H86 BCO 5.35714
145 1M5B BN1 5.36585
146 2EVL GAL SPH EIC 5.36585
147 4JZX 476 5.36585
148 1RF6 GPJ 5.36585
149 1RF6 S3P 5.36585
150 3GZ9 D32 5.36585
151 3KIF GDL 5.66038
152 2QZO KN1 5.85366
153 2BJ4 OHT 5.85366
154 4TUZ 36J 5.85366
155 1GKZ ADP 5.85366
156 5DXE EST 5.85366
157 4MGB XDH 5.85366
158 2QA8 GEN 5.85366
159 4MGD 27N 5.85366
160 4TV1 36M 5.85366
161 3UUD EST 5.85366
162 4URN NOV 5.85366
163 4MG8 27J 5.85366
164 5WGQ EST 5.85366
165 5HYR EST 5.85366
166 5WGD EST 5.85366
167 3TO7 COA 5.85366
168 4DXJ 0M9 5.85366
169 4DXJ IPE 5.85366
170 1ID0 ANP 5.92105
171 2WPX ACO 6.34146
172 1KZN CBN 6.34146
173 2VL8 CTS 6.34146
174 1CER NAD 6.34146
175 2VL8 UDP 6.34146
176 4CMI NAP 6.34146
177 3WDM ADN 6.34146
178 4CME NAP 6.34146
179 2UYT LRH 6.34146
180 2UYT ADP 6.34146
181 2HHP FLC 6.82927
182 1NRL SRL 6.82927
183 4EI7 GDP 6.82927
184 4L77 CNL 6.82927
185 1FCH TYR GLN SER LYS LEU 6.82927
186 3ZY6 GFB 6.82927
187 4IHL 1F5 6.82927
188 3KDU NKS 6.82927
189 1K7L 544 6.82927
190 2DTX BMA 6.82927
191 5FPX GLY SER SER HIS HIS HIS HIS HIS 7.07965
192 2HJ3 FAD 7.2
193 1QZR ANP 7.31707
194 1QZR CDX 7.31707
195 5F5R ANP 7.31707
196 4IPE ANP 7.31707
197 4IVG ANP 7.31707
198 4N3A UDP 7.31707
199 5BNW 12V 7.31707
200 4GYW UDP 7.31707
201 3LLI FAD 7.31707
202 1WS1 BB2 7.31707
203 3R5Z F42 7.58621
204 1UUO BRF 7.80488
205 1UUO ORO 7.80488
206 1UUO FMN 7.80488
207 1BUC CAA 7.80488
208 2J4D FAD 7.80488
209 4LY9 1YY 7.80488
210 4LY9 S6P 7.80488
211 2XTZ GSP 7.80488
212 1PZO CBT 7.80488
213 4XB4 45D 7.89474
214 1U3R 338 8.29268
215 2I0G I0G 8.29268
216 2YJD YJD 8.29268
217 1YYE 196 8.29268
218 2P1C GG3 8.29268
219 3V91 UPG 8.29268
220 3OLL EST 8.29268
221 4HIA FMN 8.29268
222 4J24 EST 8.29268
223 2Q2V NAD 8.29268
224 5MW4 5JU 8.78049
225 5OSW DIU 8.78049
226 2IOR ADP 8.93617
227 3RV5 DXC 8.98876
228 2RKN LP3 9.09091
229 4DJA FAD 9.26829
230 4DJA DLZ 9.26829
231 1CF2 NAP 9.26829
232 3KIH GDL 9.27835
233 5J6D 6H5 9.7561
234 4RHE FMN 9.7561
235 1N7G GDR 9.7561
236 1U3D FAD 9.7561
237 6A56 LAT 9.7561
238 5XJ8 NKO 9.95025
239 5IDM ANP 10.0559
240 5CJH 522 10.2439
241 3TDC 0EU 10.2439
242 1VGV UD1 10.7317
243 4U63 FAD 10.7317
244 3AHQ FAD 10.7317
245 4NB5 2JT 11.1111
246 3F3E LEU 11.2195
247 1KOR ANP 11.7073
248 1KOR ARG 11.7073
249 1KOR SIN 11.7073
250 3QCP FAD 11.7073
251 5X1M DHB 11.7073
252 2WT9 NIO 11.7073
253 5X1M THG 11.7073
254 5UXF 2BA 11.7073
255 1N62 FAD 12.0482
256 2OO0 PLP 12.1951
257 2W41 ADP 12.1951
258 5K8B PDG 12.1951
259 4QVX 3CQ 12.5749
260 2J4K U5P 12.6829
261 5VE5 GSH 12.6829
262 5CB8 ADX 13.198
263 6D28 NEC 14.6341
264 5YJF SAH 15.122
265 4YSX EPH 15.4255
266 3KFC 61X 16.5854
267 6MPT C30 17.0732
268 6CC0 EWM 17.561
269 3D36 ADP 18.0488
270 2OFW ADX 18.0488
271 2Q4X HMH 18.5366
272 3L9W GSH 19.5122
273 3H4T UDP 20.9756
274 1Y8O ADP 21.0938
275 1ZSQ PIB 21.9512
276 5Z84 PEK 22.3529
277 2DYR PEK 22.3529
278 2EV1 OLA 24.878
Pocket No.: 2; Query (leader) PDB : 4WGF; Ligand: HX2; Similar sites found with APoc: 334
This union binding pocket(no: 2) in the query (biounit: 4wgf.bio1) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 5NNT DPV None
2 2BW7 APC None
3 4OIV XX9 None
4 2YJ0 COA None
5 2FKW RG1 None
6 1QIN GIP None
7 5UEX 89D None
8 4KBS PX2 None
9 5N8V KZZ None
10 3NFD COA None
11 2PEH LYS ARG LYS SER ARG TRP ASP GLU THR PRO None
12 3QP8 HL0 None
13 3TKY SAH 0.97561
14 2PXX SAH 1.46341
15 6AP6 TLF 1.46341
16 3OJI PYV 1.5873
17 4DDS 0J7 1.95122
18 2A3I C0R 1.95122
19 4DDY DN6 1.95122
20 3ROE THM 1.95122
21 4DE3 DN8 1.95122
22 5JO1 6LM 1.95122
23 4UA7 3GK 1.95122
24 4DE2 DN3 1.95122
25 4UAA 3GK 1.95122
26 6BU3 3GK 1.95122
27 1P3D ANP 1.95122
28 5A8E XTK 1.95122
29 6BT6 3GK 1.95122
30 1NJJ GET 1.95122
31 4DE1 0J6 1.95122
32 3RO7 TDR 1.95122
33 4DS8 A8S 1.95122
34 2WUF KEM 1.95122
35 4DE0 0JB 1.95122
36 4B5P ACO 2
37 4RLT FSE 2.04082
38 4MUV PCG 2.11268
39 1POC GEL 2.23881
40 1OGX EQU 2.29008
41 2FP2 TSA 2.40964
42 5WL1 D3D 2.43902
43 5WL1 CUY 2.43902
44 1YMT DR9 2.43902
45 4NJH 2K8 2.43902
46 4NJH SAM 2.43902
47 5E58 CPZ 2.43902
48 3JRS A8S 2.43902
49 1N4H REA 2.43902
50 1ZDT PEF 2.43902
51 1HG4 LPP 2.43902
52 5KBZ 3B2 2.43902
53 4Y9J UCC 2.43902
54 4ZBR DIF 2.43902
55 4U0S ADP 2.43902
56 1YP0 PEF 2.43902
57 5HGZ ACO 2.43902
58 3WQM B29 2.43902
59 3OV6 MK0 2.43902
60 2HI4 BHF 2.43902
61 4W97 UCA 2.5
62 1VHT BA3 2.75229
63 1C9K 5GP 2.77778
64 4QJR PIZ 2.85714
65 4K4D HFQ 2.91971
66 4OYA 1VE 2.92683
67 6EOP F15 2.92683
68 4UDB CV7 2.92683
69 5HES 032 2.92683
70 3HCN CHD 2.92683
71 4ITM ATP 2.92683
72 3NHT U46 2.92683
73 1ZMT RNO 2.92683
74 3VRV YSD 2.92683
75 3HYW DCQ 2.92683
76 4YDQ HFG 2.92683
77 4YDQ ANP 2.92683
78 5UQK U2F 2.92683
79 3L9R L9R 2.92683
80 5MBC FMN 2.92683
81 3A51 VDY 2.92683
82 1UKZ ADP 2.95567
83 1UKZ AMP 2.95567
84 4K7O EKZ 2.97619
85 3TL1 JRO 3.14465
86 1OQC FAD 3.2
87 3KP6 SAL 3.31126
88 5UR6 8KM 3.31492
89 4WVO 3UZ 3.31492
90 2E2R 2OH 3.41463
91 1YOK P6L 3.41463
92 1DKF OLA 3.41463
93 2R0N TGC 3.41463
94 1FM9 9CR 3.41463
95 1RDT L79 3.41463
96 6AP8 BNY 3.41463
97 5BVE 4VG 3.41463
98 5G57 6M5 3.41463
99 4M4Q 21A 3.41463
100 5BYK A3P 3.41463
101 5BYK OAQ 3.41463
102 1YUC EPH 3.41463
103 1ZDU P3A 3.41463
104 3BF1 ADP 3.41463
105 4D9M 0JO 3.41463
106 5UN9 NHT 3.41463
107 4V24 GYR 3.41463
108 2BTO GTP 3.41463
109 3ET1 ET1 3.41463
110 2JAP J01 3.41463
111 3H0A 9RA 3.41463
112 3MBG FAD 3.59712
113 2VBQ BSJ 3.63636
114 5IF4 6AK 3.77358
115 3K87 FAD 3.78378
116 4UYF 73B 3.8961
117 5O42 NAD 3.90244
118 5O42 BGC 3.90244
119 5O42 9JW 3.90244
120 3AJH BL3 3.90244
121 3HB5 E2B 3.90244
122 3HB5 NAP 3.90244
123 1UBY DMA 3.90244
124 3P0K FAD 3.90244
125 5J47 6JJ 3.90244
126 4XRQ 1B0 3.90244
127 3QJ4 FAD 3.90244
128 1UOU CMU 3.90244
129 2AK3 AMP 3.90244
130 4KIB SAH 3.90244
131 4Q9M 2ZW 3.90244
132 4Q9M FPP 3.90244
133 2R40 EPH 3.90244
134 2BCG GDP 3.90244
135 1ZOA 140 3.90244
136 2D3M COA 3.90244
137 2BCG GER 3.90244
138 2YDW WSH 3.92157
139 3O55 FAD 4
140 3S0E EOL 4.20168
141 3IX9 NDP 4.21053
142 4ELG 52I 4.21687
143 4ELG 52J 4.21687
144 4EKQ NPO 4.27807
145 3HUJ AGH 4.39024
146 4ORM ORO 4.39024
147 4ORM FMN 4.39024
148 4ORM 2V6 4.39024
149 4NKW PLO 4.39024
150 4M73 M72 4.39024
151 4M73 SAH 4.39024
152 4EMI FAD 4.39024
153 1DMH LIO 4.39024
154 5KOR GDP 4.39024
155 2Q8G AZX 4.39024
156 2X24 X24 4.39024
157 4CZG ADP 4.39024
158 3B1Q NOS 4.39024
159 5X5M 7YU 4.39024
160 1LBT T80 4.39024
161 4UYG 73B 4.4586
162 5BVT PAM 4.47761
163 4BJX 73B 4.57516
164 4B6C B5U 4.59184
165 5VOM 9GY 4.69799
166 3ZLM ANP 4.78723
167 3G4Q MCH 4.79452
168 5KAU RHQ 4.84848
169 1M2Z BOG 4.87805
170 1M2Z DEX 4.87805
171 3LN0 52B 4.87805
172 4E2J MOF 4.87805
173 3GN8 DEX 4.87805
174 2C78 PUL 4.87805
175 3CV3 UDP 4.87805
176 2BIF BOG 4.87805
177 1NHZ 486 4.87805
178 5EIB GTP 4.87805
179 4LSJ LSJ 4.87805
180 4LNU GTP 4.87805
181 3RYC GTP 4.87805
182 3OID TCL 4.87805
183 2XBK XBK 4.87805
184 6CGN DA 4.87805
185 4DP3 NDP 4.87805
186 5EYP LOC 4.87805
187 5ZKC 3C0 4.87805
188 3RYC GDP 4.87805
189 6F70 GSH 4.87805
190 4OAS 2SW 5.20833
191 3B6C SDN 5.36585
192 3GKJ HC3 5.36585
193 5MOB A8S 5.36585
194 3Q9T FAY 5.36585
195 5KBE IPH 5.36585
196 3KDJ A8S 5.36585
197 4BR5 ANP 5.36585
198 1BW9 PPY 5.36585
199 3SE5 ANP 5.4878
200 4WT2 3UD 5.71429
201 5AAV GW5 5.85366
202 2JFZ DGL 5.85366
203 2JFZ 003 5.85366
204 2QE4 JJ3 5.85366
205 2E9L PLM 5.85366
206 5NE5 KIF 5.85366
207 1FL2 FAD 5.85366
208 3D78 NBB 5.88235
209 6D6L FY4 5.88235
210 1RV1 IMZ 5.88235
211 1M48 FRG 6.01504
212 5ITZ GTP 6.20155
213 5ITZ GDP 6.20155
214 1N5S ADL 6.25
215 2NP9 YE1 6.34146
216 1KPG 16A 6.34146
217 1GNI OLA 6.34146
218 3FC4 EDO 6.34146
219 4Y30 49L 6.34146
220 4Y30 SAH 6.34146
221 5WIU AQD 6.34146
222 5LKT BCO 6.34146
223 5FS0 5JC 6.82927
224 5M36 9SZ 6.82927
225 1FO3 KIF 6.82927
226 1X9D SMD 6.82927
227 4CYD CMP 6.82927
228 6BR8 6OU 6.82927
229 5M37 9SZ 6.82927
230 4WQ2 3SU 6.93642
231 4JGX PLM 6.97674
232 1N8V BDD 7.14286
233 4LA7 A1O 7.25389
234 4FHD EEM 7.31707
235 4FHD 0TT 7.31707
236 1NP7 FAD 7.31707
237 4WO4 JLS 7.31707
238 3RUG DB6 7.31707
239 4QWT ACD 7.31707
240 4OIC A8S 7.31707
241 2OBF F83 7.31707
242 6FS0 E4W 7.31707
243 4O1Z MXM 7.80488
244 2YOO K2B 7.80488
245 3RUV ANP 8.29268
246 2PX6 DH9 8.29268
247 2C9E PID 8.29268
248 5U5G NAP 8.29268
249 6C8R EQV 8.29268
250 5LJ0 6XX 8.46154
251 5MWE TCE 8.64198
252 4CVZ TYR GLU LEU ASP GLU LYS PHE ASP ARG LEU 8.78049
253 5IKR ID8 8.78049
254 3NZW BOC TY5 ALA RE0 ABN 8.78049
255 4WPF 3SN 8.78049
256 5NI5 8YB 8.78049
257 5NTW 98N 8.78049
258 6ESN BWE 8.78049
259 4P53 NAI 8.78049
260 4J7Q B7N 9.26829
261 2NU8 COA 9.26829
262 5ZBC FAD 9.26829
263 3QDJ ALA ALA GLY ILE GLY ILE LEU THR VAL 9.26829
264 4OHU NAD 9.26829
265 4OHU 2TK 9.26829
266 5LX9 OLB 9.26829
267 3ZGJ RMN 9.26829
268 5LX9 OLA 9.26829
269 6GL8 F3Q 9.30233
270 4P6W MOF 9.7561
271 1P1M MET 9.7561
272 5C0C ARG GLN PHE GLY PRO ASP TRP ILE VAL ALA 10
273 3FS1 MYR 10.2439
274 1PZL MYR 10.2439
275 2Y31 SMQ 10.2439
276 3WCS MAN NAG GAL 10.2439
277 3FS1 ALA ALA LEU ALA ALA LEU LEU ALA ALA 10.2439
278 4BNU 9KQ 10.4089
279 6HH6 A3R 10.7317
280 3UA1 08Y 10.7317
281 3CX5 SMA 11.0236
282 2H7C COA 11.2195
283 6F6E PLM 11.2195
284 3WCA FPS 11.2195
285 3KXC PLM 11.3402
286 4PYW ACE THR THR ALA ILE NH2 11.7073
287 2UUU FAD 11.7073
288 2UUU PL3 11.7073
289 4EMJ FAD 12.1495
290 1M21 PHE CSI LEU PHA 12.1951
291 5V13 JH3 12.1951
292 1NYT NAP 12.1951
293 2IFB PLM 12.2137
294 5N17 8FK 12.3188
295 5UGW GSH 12.5714
296 5Y02 HBX 13.0841
297 4OPC PGT 13.1707
298 5TPR NAD 13.1707
299 3JZ4 NAP 13.1707
300 5KKB BMA NAG MAN MAN MAN MAN MAN MAN MAN 13.6585
301 2NAD NAD 13.6585
302 5ECP ATP 13.6585
303 3G58 988 14.1463
304 1XON PIL 14.1463
305 3G4G D71 14.1463
306 2WTN FER 14.6341
307 3DZT EAH 15.6098
308 5LWY OLA 15.9664
309 4D7M TDC 16.0976
310 4QBK 3NZ 16.4948
311 4I4B 1CV 16.5854
312 5I7S NAD 16.5854
313 5I7S E9P 16.5854
314 1XMY ROL 17.0732
315 3GWT 066 17.0732
316 1XM4 PIL 17.0732
317 5OHJ 9VE 17.0732
318 1XMU ROF 17.0732
319 5HIP 61O 17.561
320 4ZOH MCN 19.5122
321 2PEZ DAT 20.6704
322 2PEZ GGZ 20.6704
323 3QP4 HL0 21.4286
324 4IXW IXW 21.4634
325 2Y69 CHD 22.093
326 5Z84 CHD 22.3529
327 5W97 CHD 22.3529
328 5ZCO CHD 22.3529
329 5ZCO PEK 22.3529
330 2DYS PEK 22.3529
331 5ZCO TGL 22.3529
332 1CX4 CMP 22.9268
333 1IID NHM 25.3659
334 2GSD NAD 28.7805
Pocket No.: 3; Query (leader) PDB : 4WGF; Ligand: HX2; Similar sites found with APoc: 532
This union binding pocket(no: 3) in the query (biounit: 4wgf.bio1) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 5F1R 42O None
2 3GWL FAD None
3 5V4R MGT None
4 5MT9 ARG None
5 5MT9 SRO None
6 5N7O 69Y None
7 5JF2 SF7 None
8 3R1V AZB None
9 2VWA PTY None
10 6EVN PRO PRO GLY PRO ALA GLY PRO PRO GLY None
11 1U1B PAX None
12 2QO4 CHD None
13 1XXA ARG None
14 4K49 HFQ None
15 4WG0 CHD None
16 1FK5 OLA None
17 4RYV ZEA None
18 2HFN FMN None
19 1UO5 PIH None
20 4INW 1EY None
21 1UVC STE None
22 2EI4 22B 0.97561
23 3EKK GS2 0.97561
24 5K53 STE 1.46341
25 3VVY ET 1.54639
26 3R96 AMP 1.59574
27 3R96 ACO 1.59574
28 3D04 SAK 1.88679
29 5BQI GSH 1.94805
30 5BQI 4UL 1.94805
31 2OBD PCW 1.95122
32 4EWN 0VR 1.95122
33 5WX3 COA 1.95122
34 4DOO DAO 1.95122
35 4UCC ZKW 1.95122
36 5DUF G7A 1.95122
37 4X8O AP5 1.95122
38 4ASJ N6A 1.95122
39 5VFC 9BA 1.95122
40 4V3I ASP LEU THR ARG PRO 1.95122
41 5L92 MLA 1.95122
42 5OLK DTP 1.95122
43 2O5L MNR 1.96078
44 4I67 G G G RPC 2.29885
45 5B0I BOG 2.33236
46 1TW4 CHD 2.4
47 2GTE VA 2.41935
48 5C9J DAO 2.43902
49 1NQ7 HIS LYS ILE LEU HIS ARG LEU LEU GLN GLU 2.43902
50 1H9G COA MYR 2.43902
51 2FV5 541 2.43902
52 5N9T 8QQ 2.43902
53 6C1R EFD 2.43902
54 4BJZ FAD 2.43902
55 4BJZ P3A 2.43902
56 1OKC CXT 2.43902
57 3LDW IPE 2.43902
58 1XW6 GSH 2.43902
59 5IXK 6EW 2.43902
60 4H6Q TFB 2.43902
61 4X6F 3XU 2.43902
62 3HX3 RET 2.43902
63 3FUU ADN 2.43902
64 4E3Q PMP 2.43902
65 3MDV CL6 2.43902
66 3SQP 3J8 2.43902
67 1EBL COA 2.43902
68 5UFN SAH 2.43902
69 4RQL SNE 2.43902
70 5Y79 3PG 2.43902
71 5C9J STE 2.43902
72 3ANP DCC 2.45098
73 1SBR VIB 2.5
74 3KPX CZH 2.52525
75 3E3U NVC 2.53807
76 4JE7 BB2 2.53807
77 3RWP ABQ 2.57235
78 5IJJ I6P 2.60417
79 1T0I FMN 2.6178
80 1Q1Y BB2 2.6178
81 3G5K BB2 2.73224
82 3SFI 3SF 2.92683
83 5LOF 70R 2.92683
84 1IYK MYA 2.92683
85 5L7G LYS SER LEU LEU GLN GLN LEU LEU THR GLU 2.92683
86 5B25 4QJ 2.92683
87 2C43 COA 2.92683
88 1EKO NAP 2.92683
89 3L9R L9Q 2.92683
90 3PG7 PTY 2.92683
91 6A5Y 9R0 2.92683
92 6BMS PLM 2.92683
93 5X3R 7Y3 2.92683
94 1LVK MNT BEF 2.92683
95 3WH1 NAG NAG NAG NAG 2.92683
96 3I53 SAH 2.92683
97 1J78 VDY 2.92683
98 3IQE F42 2.92683
99 3IQE H4M 2.92683
100 5G3R NAG 2.92683
101 3ABA FLI 2.92683
102 2V6K TGG 2.92683
103 2OHV NHL 2.92683
104 1DGH NDP 2.92683
105 4H6U ACO 3
106 1JF0 CZH 3.07692
107 2CIG 1DG 3.14465
108 2EW5 Y12 3.31492
109 2OI9 GLN LEU SER PRO PHE PRO PHE ASP LEU 3.35196
110 1DKF BMS 3.41463
111 5C1M OLC 3.41463
112 2WSA MYA 3.41463
113 2WSA 646 3.41463
114 5K52 OCD 3.41463
115 2XSU PIE 3.41463
116 6H21 UD1 3.41463
117 2WH8 II2 3.41463
118 6BQC LOP 3.41463
119 6B5G CQY 3.41463
120 6B5G NAD 3.41463
121 3BJC WAN 3.41463
122 1RQJ RIS 3.41463
123 3SHZ 5CO 3.41463
124 3TGE TGE 3.41463
125 5N69 2OW 3.41463
126 4LPG 1MV 3.41463
127 4N4J HG1 3.41463
128 3H0A D30 3.41463
129 1D5Z ACE ALC ARG ALA ODA SER LEU NH2 3.41463
130 4HEE 14R 3.41463
131 3AI3 SOE 3.41463
132 4GBD MCF 3.41463
133 4ONA UW1 3.41463
134 5C1M CLR 3.41463
135 2VZZ SCA 3.41463
136 1IH7 GMP 3.41463
137 3H78 BE2 3.41463
138 6BYM HC3 3.44828
139 5UWA 8ND 3.44828
140 5YWX 93C 3.53535
141 5YWX GSH 3.53535
142 6CHP F0Y 3.72671
143 5D9J 0N8 3.74332
144 4NAT ADP 3.75
145 4NAT 2W5 3.75
146 4BVM VCA 3.7594
147 4BVM PLM 3.7594
148 2NNQ T4B 3.81679
149 5V3Y 5V8 3.90244
150 4C2X NHW 3.90244
151 5AZC PGT 3.90244
152 4G31 0WH 3.90244
153 5N5U 7N8 3.90244
154 2A1L PCW 3.90244
155 5N5U AMP 3.90244
156 6ARJ BW4 3.90244
157 3VHZ SOG 3.90244
158 3CGD NAD 3.90244
159 3CGD FAD 3.90244
160 3RMK BML 3.90244
161 3CGD COA 3.90244
162 3FWN 6PG 3.90244
163 3FWN ATR 3.90244
164 3UR0 SVR 3.90244
165 6ARJ SAH 3.90244
166 5FBN 5WF 3.90244
167 3EE4 MYR 3.90244
168 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 3.90244
169 2ISJ FMN 3.90244
170 2XFH CL6 3.90244
171 5CC2 CKA 3.90244
172 4ZW9 GLC 3.90244
173 4ZW9 BGC 3.90244
174 1G2N EPH 3.90244
175 6CEP NAD 3.90244
176 3O3R NAP 3.90244
177 2F5T MAL 3.90244
178 5UI2 EQ3 3.90244
179 4P42 PEE 3.90244
180 3WBG 2AN 3.92157
181 1WUB OTP 3.93258
182 3OGN 3OG 4.03226
183 1X0P FAD 4.1958
184 5CHR 4NC 4.37956
185 3W54 RNB 4.39024
186 4JD3 PLM 4.39024
187 4JD3 COA 4.39024
188 5JKG 6LF 4.39024
189 4TWP AXI 4.39024
190 3E8T UQ8 4.39024
191 3QMK SGN IDS SGN IDS 4.39024
192 4F7E 0SH 4.39024
193 4OMJ 2TX 4.39024
194 2BHZ MAL 4.39024
195 4MIB 28M 4.39024
196 1OLM VTQ 4.39024
197 3HDY GDU 4.39024
198 3HDY FDA 4.39024
199 1Z8O DEB 4.39024
200 3HDY FAD 4.39024
201 5AG3 3EB 4.39024
202 4ZW3 4S9 4.39024
203 4EMI NAD 4.39024
204 4FAJ LEU VAL THR LEU VAL PHE VAL 4.39024
205 4ZAL FNR 4.39024
206 4ZAL 4LR 4.39024
207 6FQZ 6PG 4.39024
208 4CZG QH3 4.39024
209 1TV5 N8E 4.39024
210 1XVB BHL 4.39024
211 1UDY CS8 4.39024
212 1R5L VIV 4.39024
213 5IM3 DTP 4.39024
214 3W68 VIV 4.39024
215 2YVJ FAD 4.39024
216 1FP1 HCC 4.39024
217 4Y9T PA1 4.39024
218 1OPK MYR 4.39024
219 1TV5 A26 4.39024
220 3X1M COA 4.40252
221 3QKD HI0 4.41989
222 5HZ9 5M8 4.44444
223 1XZ3 ICF 4.5977
224 3IIS PID 4.63576
225 4CL6 7SB 4.67836
226 3E7O 35F 4.87805
227 4Q0A GLY HIS LYS ILE LEU HIS ARG LEU LEU GLN 4.87805
228 5UC1 486 4.87805
229 1EM6 CP4 4.87805
230 5LGA 6VH 4.87805
231 5UFS 1TA 4.87805
232 2RHQ GAX 4.87805
233 3BQD DAY 4.87805
234 6BMM OLB 4.87805
235 3I51 6PL 4.87805
236 5EEH P9P 4.87805
237 5EEH SAH 4.87805
238 3ICS COA 4.87805
239 3ICT COA 4.87805
240 6CR2 LFV 4.87805
241 4BFW ZVW 4.87805
242 5TIV A3P 4.87805
243 3LSJ COA PLM 4.87805
244 5EYP GTP 4.87805
245 5X93 K87 4.87805
246 2UXI G50 4.87805
247 2OXN OAN 4.87805
248 4HBM 0Y7 5
249 3HRD MCN 5
250 4MNS 2AX 5.03145
251 1TID ATP 5.04202
252 4AZP A9M 5.07246
253 5HZ5 65X 5.22388
254 5W7B MYR 5.36585
255 3E70 GDP 5.36585
256 2XXP DSL 5.36585
257 5H94 LYS MET ASN THR GLN PHE THR ALA VAL 5.36585
258 2RH1 CLR 5.36585
259 6B21 C9V 5.36585
260 5C2H 4PX 5.36585
261 5GK9 ACO 5.36585
262 2RH1 CAU 5.36585
263 5B0W 22B 5.36585
264 5C2H 4XU 5.36585
265 4RPL FAD 5.36585
266 3W5N RAM 5.36585
267 3VSS FRU 5.36585
268 1JQI CAA 5.36585
269 3KRO DST 5.36585
270 3KRO IPE 5.36585
271 3LOO B4P 5.36585
272 1PGP 6PG 5.36585
273 4JZB P2H 5.36585
274 6G33 5ID 5.36585
275 3GF4 U5P 5.36585
276 5GUE GGS 5.36585
277 2O3Z AI7 5.36585
278 3RLF MAL 5.36585
279 1C1X HFA 5.36585
280 5GWE GWM 5.36585
281 5EW0 3C7 5.36585
282 5XJN 88L 5.36585
283 5V03 658 5.36913
284 1LQY BB2 5.43478
285 2HW2 RFP 5.59441
286 6C7R EO4 5.6
287 3QLM PLM 5.64516
288 2QQC AG2 5.66038
289 2QQD AG2 5.66038
290 2D5Z L35 5.67376
291 4OGN 2U5 5.71429
292 4WRI OKA 5.72917
293 1N13 AG2 5.76923
294 1MT1 AG2 5.76923
295 1DQE BOM 5.83942
296 5LXT 7AK 5.85366
297 1EWF PC1 5.85366
298 4F06 PHB 5.85366
299 1MV8 NAD 5.85366
300 1MUU NAD 5.85366
301 1AKY AP5 5.85366
302 2QJY SMA 5.85366
303 2VAT COA 5.85366
304 5LXT GTP 5.85366
305 3NT6 COA 5.85366
306 3NTA COA 5.85366
307 3NTD COA 5.85366
308 1EE0 CAA 5.85366
309 3PIJ FRU 5.85366
310 1D6H COA 5.85366
311 2IVN ANP 5.85366
312 4KCF AKM 5.85366
313 4NU0 AP5 5.85366
314 4ASE AV9 5.85366
315 6IIU A8X 5.85366
316 1DEK DGP 5.85366
317 5A4W QCT 5.85366
318 4QJK COA 5.85366
319 3ZS7 ATP 5.85366
320 6CAY ERG 5.91716
321 2V5E SCR 5.94059
322 1S17 GNR 6.11111
323 6GBV FMN 6.16438
324 3L1N PLM 6.18557
325 5CSD ACD 6.28931
326 3QCJ NX4 6.34146
327 2J8C U10 6.34146
328 2J8C SPO 6.34146
329 4RHP PEF 6.34146
330 3GFZ FMN 6.34146
331 3Q8G PEE 6.34146
332 1KPH 10A 6.34146
333 1TMX HGX 6.34146
334 1W8S FBP 6.34146
335 1KPH SAH 6.34146
336 4CRL C1I 6.34146
337 1KPG SAH 6.34146
338 1PFK ADP 6.34146
339 2WPW ACO 6.34146
340 2GSQ GBI 6.43564
341 5MTE BB2 6.56934
342 1NTV ASN PHE ASP ASN PRO VAL TYR ARG LYS THR 6.57895
343 2VBU CDP 6.61765
344 5LGD PLM 6.70391
345 2PR5 FMN 6.81818
346 1M13 HYF 6.82927
347 6BR9 PGV 6.82927
348 3SP6 IL2 6.82927
349 5HCN DAO 6.82927
350 3HKW IX6 6.82927
351 1HK8 DGT 6.82927
352 3FEI CTM 6.82927
353 6BR9 6OU 6.82927
354 1OWB NAD 6.82927
355 6BR8 PGV 6.82927
356 2E3N 6CM 6.82927
357 2WKQ FMN 6.82927
358 2JLD AG1 6.82927
359 5UJ3 CE4 6.82927
360 1W2Y DUN 6.82927
361 4EOX 0S5 6.89655
362 5IVX ARG GLY PRO GLY ARG ALA PHE VAL THR ILE 7
363 1ZT1 PHE GLU ALA ASN GLY ASN LEU ILE 7
364 3G08 FEE 7.07071
365 1LEK GLU GLN TYR LYS PHE TYR SER VAL 7.07071
366 2QM9 TDZ 7.09677
367 5Z1N PEF 7.14286
368 1Z83 AP5 7.14286
369 4UA3 COA 7.2165
370 5FH7 5XL 7.25806
371 2FR3 REA 7.29927
372 4V1T ADP 7.31707
373 4Q86 AMP 7.31707
374 4KWD JF2 7.31707
375 1LSH PLD 7.31707
376 3B99 U51 7.31707
377 2HU5 GLY PHE 7.31707
378 3PVW QRX 7.31707
379 1N9L FMN 7.33945
380 1CBK ROI 7.5
381 2OKL BB2 7.56757
382 5X4Q 7Z6 7.80142
383 3TJH SER PRO LEU ASP SER LEU TRP TRP ILE 7.80488
384 1OUK 084 7.80488
385 6B2M COA 7.80488
386 1U8V FAD 7.80488
387 5IBE 69M 7.80488
388 4COL DTP 7.80488
389 4XVX P33 FDA 7.80488
390 3Q2H QHF 7.80488
391 3KF3 FRU 7.80488
392 5K0S 0OU 7.80488
393 4EES FMN 7.82609
394 5G3N X28 7.87402
395 4F4S EFO 7.89474
396 1H0A I3P 8.22785
397 6BJ3 ILE PRO LEU THR GLU GLU ALA GLU LEU 8.29268
398 5EK3 5PK 8.29268
399 4IGH 1EA 8.29268
400 4IGH FMN 8.29268
401 4IGH ORO 8.29268
402 4XU6 TDA 8.29268
403 3PVT 3HC 8.29268
404 3V49 PK0 8.29268
405 4QMN DB8 8.29268
406 2ZSH GA3 8.29268
407 1LOX RS7 8.29268
408 1E8G FCR 8.29268
409 1UHK CZN 8.37696
410 4H07 IPH 8.44156
411 3U3U EAH 8.78049
412 5NTP 98E 8.78049
413 3JRX S1A 8.78049
414 5APK 76E 8.78049
415 2FDW D3G 8.78049
416 4CDN FAD 8.78049
417 1L0I PSR 8.97436
418 2ZCQ B65 9.26829
419 5JHD GLY ILE LEU GLY PHE VAL PHE THR LEU 9.26829
420 1OGA GLY ILE LEU GLY PHE VAL PHE THR LEU 9.26829
421 2GWH PCI 9.26829
422 5ISZ GLY ILE LEU GLY PHE VAL PHE THR LEU 9.26829
423 4OGQ 2WA 9.26829
424 2IZ1 ATR 9.26829
425 2IZ1 RES 9.26829
426 3QFJ LEU LEU PHE GLY PHE PRO VAL TYR VAL 9.26829
427 4OGQ 2WM 9.26829
428 5JZI LYS LEU VAL ALA LEU GLY ILE ASN ALA VAL 9.26829
429 1AUA BOG 9.26829
430 4OGQ SQD 9.26829
431 3R9C ECL 9.26829
432 4OGQ 7PH 9.26829
433 1CMC SAM 9.61539
434 5EFW FMN 9.65517
435 4V2O CLQ 9.7561
436 5U98 1KX 9.7561
437 5T70 THR SER ASN LEU GLN GLU GLN ILE GLY TRP 9.7561
438 2OFV 242 9.7561
439 4R6W PC 9.7561
440 1QNF HDF 9.7561
441 4RW3 PLM 9.7561
442 3RET PYR 9.90099
443 3RET SAL 9.90099
444 1JHG TRP 9.90099
445 5XJ7 87O 9.95025
446 4XIZ LPP 10
447 1GHE ACO 10.1695
448 5SVV FMN 10.219
449 1R6N 434 10.2439
450 3SCM LGN 10.2439
451 4Q0P 0MK 10.2439
452 1QV1 CZH 10.2564
453 5DKK FMN 10.3448
454 5HH0 COA 10.5
455 2YNE NHW 10.7317
456 2YNE YNE 10.7317
457 2YNC YNC 10.7317
458 3QUZ QUV 10.7317
459 6GH1 ARG LEU PRO ALA LYS ALA PRO LEU LEU 10.7317
460 2Q2Y MKR 10.7317
461 2Q2Y ADP 10.7317
462 3BIY 01K 10.7317
463 4PFC 2QX 10.7317
464 2JJK R15 10.7317
465 1XX4 BAM 10.7317
466 2IBZ UQ6 11.0236
467 2IBZ SMA 11.0236
468 1SIV PSI 11.1111
469 6F68 4EU 11.2195
470 4C9G CXT 11.2195
471 6F68 GSH 11.2195
472 3RDE OYP 11.2195
473 2Z6D FMN 11.5385
474 3EM0 CHD 11.5942
475 2VBF TPP 11.7073
476 1Y75 NAG 11.8644
477 1G27 BB1 11.9048
478 2WOR 2AN 12
479 2D5X L35 12.0567
480 4RFM 3P6 12.1951
481 5ICE SAH 12.1951
482 5ICE 2H4 12.1951
483 3T6E UQ9 12.1951
484 5MU6 KFK 12.1951
485 5MU6 MYA 12.1951
486 1SAY PYR 12.1951
487 2B4D COA 12.2807
488 2GJ3 FAD 12.5
489 4RC8 STE 12.6829
490 3COW 52H 12.6829
491 1KYZ SAH 12.6829
492 2JC9 ADN 12.6829
493 1EZV SMA 12.7273
494 5Y02 MXN 13.0841
495 2W90 6PG 13.1707
496 4Z87 5GP 13.1707
497 5UC9 MYR 13.1707
498 5ECP MET 13.6585
499 5ECP JAA 13.6585
500 6EQ8 BQZ 13.6585
501 1T57 FMN 14.5631
502 1W96 S1A 14.6341
503 4IBF 1D5 14.7287
504 4B7H NDP 15.122
505 4YSX E23 15.4255
506 4O4Z N2O 15.5844
507 3CXH SMA 16.0714
508 4XRZ SI6 16.0976
509 2ALG DAO 16.3043
510 2ALG HP6 16.3043
511 5OM2 DXT 17.5
512 3V66 D3A 18.5366
513 4ZVV NAD 18.5366
514 4ZVV GN0 18.5366
515 5G0H E1Z