Receptor
PDB id Resolution Class Description Source Keywords
4XHV 1.23 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF DROSOPHILA SPINOPHILIN-PDZ AND A C-TERM PEPTIDE OF NEUREXIN DROSOPHILA MELANOGASTER SPINOPHILIN NEUREXIN PRAESYNAPTIC DENSITY SYNAPSE SIGNALPROTEIN
Ref.: PRESYNAPTIC SPINOPHILIN TUNES NEUREXIN SIGNALLING T ACTIVE ZONE ARCHITECTURE AND FUNCTION. NAT COMMUN V. 6 8362 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ASP SER LYS ASP VAL LYS GLU TRP TYR VAL ZN B:1831;
 Valid;
 Atoms found MORE than expected: % Diff = 1.111;
 Kd = 50 uM
n/a n/a
EDO A:1401;
 Invalid;
 none;
 submit data
62.068 C2 H6 O2 C(CO)...
CL A:1402;
 Invalid;
 none;
 submit data
35.453 Cl [Cl-]
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4XHV 1.23 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF DROSOPHILA SPINOPHILIN-PDZ AND A C-TERM PEPTIDE OF NEUREXIN DROSOPHILA MELANOGASTER SPINOPHILIN NEUREXIN PRAESYNAPTIC DENSITY SYNAPSE SIGNALPROTEIN
Ref.: PRESYNAPTIC SPINOPHILIN TUNES NEUREXIN SIGNALLING T ACTIVE ZONE ARCHITECTURE AND FUNCTION. NAT COMMUN V. 6 8362 2015
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 4XHV Kd = 50 uM ASP SER LYS ASP VAL LYS GLU TRP TYR VAL ZN n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 4XHV Kd = 50 uM ASP SER LYS ASP VAL LYS GLU TRP TYR VAL ZN n/a n/a
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 6JUE Kd = 1.1 uM LEU GLU GLU ASP GLY THR ILE ILE THR LEU n/a n/a
2 4XHV Kd = 50 uM ASP SER LYS ASP VAL LYS GLU TRP TYR VAL ZN n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: ASP SER LYS ASP VAL LYS GLU TRP TYR VAL ZN ; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Ligands (3D)
Ligand no: 1; Ligand: ASP SER LYS ASP VAL LYS GLU TRP TYR VAL ZN ; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
Feedback