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Receptor
PDB id Resolution Class Description Source Keywords
4YCA 1.81 Å EC: 1.1.1.169 EVIDENCE OF KINETIC COOPERATIVITY IN DIMERIC KETOPANTOATE RE FROM STAPHYLOCOCCUS AUREUS STAPHYLOCOCCUS AUREUS REDUCTASE DIMER ROSSMANN KINETIC COOPERATIVITY OXIDOREDU
Ref.: EVIDENCE OF KINETIC COOPERATIVITY IN DIMERIC KETOPA REDUCTASE FROM STAPHYLOCOCCUS AUREUS. BIOCHEMISTRY V. 54 3360 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NDP A:800;
B:800;
Valid;
Valid;
none;
none;
Kd = 117 nM
745.421 C21 H30 N7 O17 P3 c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4YCA 1.81 Å EC: 1.1.1.169 EVIDENCE OF KINETIC COOPERATIVITY IN DIMERIC KETOPANTOATE RE FROM STAPHYLOCOCCUS AUREUS STAPHYLOCOCCUS AUREUS REDUCTASE DIMER ROSSMANN KINETIC COOPERATIVITY OXIDOREDU
Ref.: EVIDENCE OF KINETIC COOPERATIVITY IN DIMERIC KETOPA REDUCTASE FROM STAPHYLOCOCCUS AUREUS. BIOCHEMISTRY V. 54 3360 2015
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 4YCA Kd = 117 nM NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 4YCA Kd = 117 nM NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 4YCA Kd = 117 nM NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: NDP; Similar ligands found: 172
No: Ligand ECFP6 Tc MDL keys Tc
1 NDP 1 1
2 0WD 0.827273 1
3 NAI 0.803738 0.986842
4 NMN AMP PO4 0.794643 0.948052
5 NPW 0.692308 0.962025
6 NZQ 0.686441 0.987013
7 1DG 0.68 1
8 DG1 0.68 1
9 A2R 0.650943 0.909091
10 A22 0.64486 0.934211
11 TXP 0.644628 0.924051
12 ATR 0.640777 0.894737
13 NA7 0.636364 0.886076
14 XNP 0.620968 0.949367
15 AP0 0.598361 0.948718
16 A2P 0.598039 0.881579
17 NJP 0.574803 0.923077
18 25L 0.550847 0.934211
19 ODP 0.550388 0.936709
20 NAX 0.544 0.949367
21 25A 0.53913 0.921053
22 80F 0.537879 0.914634
23 2AM 0.529412 0.87013
24 6V0 0.519685 0.974026
25 NAP 0.514493 0.922078
26 7L1 0.507143 0.763441
27 EAD 0.507143 0.949367
28 A2D 0.504673 0.921053
29 TXE 0.503876 0.935897
30 NA0 0.496454 0.910256
31 TXD 0.496124 0.911392
32 SAP 0.495575 0.875
33 AGS 0.495575 0.875
34 P1H 0.493056 0.925926
35 CO7 0.489796 0.791209
36 TAP 0.489362 0.864198
37 PAP 0.482456 0.907895
38 BA3 0.481818 0.921053
39 NAJ PZO 0.478261 0.924051
40 ATP 0.477876 0.921053
41 HEJ 0.477876 0.921053
42 B4P 0.477477 0.921053
43 AP5 0.477477 0.921053
44 ADP 0.477477 0.921053
45 OAD 0.47541 0.897436
46 AR6 0.473684 0.896104
47 AQP 0.473684 0.921053
48 5FA 0.473684 0.921053
49 APR 0.473684 0.896104
50 AN2 0.473214 0.909091
51 3OD 0.467742 0.897436
52 50T 0.464912 0.884615
53 NAJ PYZ 0.464789 0.879518
54 9X8 0.463415 0.851852
55 PO4 PO4 A A A A PO4 0.463415 0.857143
56 V3L 0.461538 0.896104
57 2A5 0.46087 0.85
58 AT4 0.460177 0.886076
59 A1R 0.459016 0.841463
60 4AD 0.459016 0.875
61 ADQ 0.459016 0.897436
62 OVE 0.458716 0.8375
63 OMR 0.458647 0.813953
64 PPS 0.457627 0.811765
65 AD9 0.456897 0.897436
66 CA0 0.45614 0.897436
67 M33 0.45614 0.884615
68 ADJ 0.455882 0.879518
69 A3P 0.455357 0.894737
70 ACP 0.452174 0.897436
71 ENP 0.451613 0.85
72 UP5 0.451128 0.948052
73 SRP 0.45 0.8625
74 ANP 0.449153 0.897436
75 ACQ 0.449153 0.897436
76 PRX 0.448276 0.82716
77 A3R 0.447154 0.841463
78 5AL 0.445378 0.884615
79 7D4 0.443478 0.8375
80 ADX 0.443478 0.811765
81 6YZ 0.438017 0.897436
82 A 0.436364 0.894737
83 AMP 0.436364 0.894737
84 4TC 0.433824 0.924051
85 7D3 0.433628 0.8375
86 DCA 0.433566 0.788889
87 ETB 0.433566 0.797753
88 BIS 0.433071 0.864198
89 1ZZ 0.433071 0.802326
90 00A 0.432 0.864198
91 ATF 0.429752 0.886076
92 DQV 0.428571 0.934211
93 0T1 0.427586 0.788889
94 5SV 0.427419 0.788235
95 8QN 0.427419 0.884615
96 3AM 0.427273 0.857143
97 N01 0.426573 0.884615
98 PR8 0.425197 0.811765
99 LAD 0.425197 0.821429
100 WAQ 0.425197 0.841463
101 DTP 0.425 0.8375
102 AMO 0.424 0.886076
103 PAJ 0.424 0.843373
104 APC 0.423729 0.886076
105 UPA 0.423358 0.935897
106 48N 0.422222 0.853659
107 FYA 0.421875 0.860759
108 PTJ 0.421875 0.853659
109 CNA 0.421429 0.910256
110 PUA 0.42069 0.9125
111 DND 0.419118 0.910256
112 NXX 0.419118 0.910256
113 AV2 0.418033 0.848101
114 COA 0.417808 0.788889
115 3UK 0.417323 0.897436
116 OOB 0.416 0.909091
117 IVC 0.415584 0.78022
118 DAT 0.415254 0.8375
119 NDO 0.414966 0.897436
120 139 0.414286 0.901235
121 B5V 0.414062 0.886076
122 T99 0.413223 0.886076
123 TAT 0.413223 0.886076
124 3AT 0.413223 0.896104
125 YLB 0.413043 0.784091
126 62F 0.4125 0.823529
127 ABM 0.412281 0.848101
128 B5M 0.412214 0.875
129 YAP 0.412214 0.875
130 YLP 0.411765 0.784091
131 NB8 0.410853 0.853659
132 ME8 0.410853 0.802326
133 SON 0.410256 0.886076
134 DLL 0.409449 0.909091
135 AHX 0.409449 0.853659
136 CAO 0.409396 0.763441
137 30N 0.409396 0.72449
138 AMX 0.409396 0.797753
139 COS 0.409396 0.771739
140 7D5 0.409091 0.8125
141 4UW 0.408759 0.9125
142 F2R 0.408451 0.825581
143 APX 0.407692 0.841463
144 SRA 0.40708 0.85
145 CMX 0.406667 0.788889
146 SCO 0.406667 0.788889
147 TYM 0.405797 0.886076
148 COD 0.405594 0.777778
149 CA6 0.405229 0.70297
150 OXK 0.405229 0.771739
151 AP2 0.405172 0.886076
152 A12 0.405172 0.886076
153 9SN 0.40458 0.853659
154 LAQ 0.404412 0.802326
155 T5A 0.404255 0.914634
156 FAM 0.403974 0.771739
157 ACO 0.403974 0.763441
158 FCX 0.403974 0.763441
159 VO4 ADP 0.403226 0.860759
160 ADP VO4 0.403226 0.860759
161 YLC 0.402878 0.823529
162 1VU 0.402597 0.763441
163 B5Y 0.401515 0.875
164 FA5 0.401515 0.886076
165 HAX 0.401316 0.771739
166 AR6 AR6 0.4 0.871795
167 CAJ 0.4 0.771739
168 AFH 0.4 0.843373
169 APU 0.4 0.923077
170 A U 0.4 0.898734
171 TXA 0.4 0.886076
172 4UU 0.4 0.948052
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4YCA; Ligand: NDP; Similar sites found with APoc: 1007
This union binding pocket(no: 1) in the query (biounit: 4yca.bio1) has 28 residues
No: Leader PDB Ligand Sequence Similarity
1 1UJ5 5RP 0.881057
2 1F06 NDP 1.02041
3 1F06 2NP 1.02041
4 5GWT NAD 1.07914
5 5GWT SIN 1.07914
6 1G8S MET 1.30435
7 3K5I AIR 1.36054
8 3GD4 FAD 1.36054
9 3GD4 NAD 1.36054
10 1D1T NAD 1.36054
11 4Q9N NAI 1.36054
12 5VKT NAP 1.65746
13 1Q9I TEO 1.70068
14 1Q9I FAD 1.70068
15 4TXI FAD 1.70068
16 3TWO NDP 1.70068
17 4K5S PM0 1.70068
18 6AIN FAD 1.70068
19 4BV6 FAD 1.70068
20 2AQJ FAD 1.70068
21 2AQJ TRP 1.70068
22 1X7D ORN 1.70068
23 1X7D NAD 1.70068
24 2BRY FAD 1.70068
25 4REP FAD 1.70068
26 4K5S FAD 1.70068
27 5L4L NAP 1.70068
28 1D7O TCL 1.70068
29 1D7O NAD 1.70068
30 1VM6 NAD 1.75439
31 1BDB NAD 1.80505
32 2B4Q NAP 1.81159
33 1JA9 NDP 1.82482
34 2GDZ NAD 1.87266
35 1ZEM NAD 1.9084
36 5B4T 3HR 1.92308
37 5B4T NAD 1.92308
38 1E6W NAD 1.92308
39 4NBW NAD 1.94553
40 2AG5 NAD 2.03252
41 5Y8L NAD 2.04082
42 5Y8L HUI 2.04082
43 2NPX NAD 2.04082
44 1LDN NAD 2.04082
45 2FZW NAD 2.04082
46 2O4C NAD 2.04082
47 5DN9 NAD 2.04082
48 4NTC FAD 2.04082
49 4R5M NAP 2.04082
50 1CDO NAD 2.04082
51 1LVL NAD 2.04082
52 1LVL FAD 2.04082
53 6A0S HSE 2.04082
54 6A0S NDP 2.04082
55 1KNR FAD 2.04082
56 5UAO FAD 2.04082
57 3IHG FAD 2.04082
58 3OA2 NAD 2.04082
59 2Q1S NAI 2.04082
60 1OC2 NAD 2.04082
61 1OC2 TDX 2.04082
62 4R5M 4NO 2.04082
63 5A04 BGC 2.04082
64 2O07 SPD 2.04082
65 2O07 MTA 2.04082
66 5AOG IAC 2.04082
67 1ZBQ NAD 2.04082
68 5Z75 NAD 2.04082
69 4A0S NAP 2.04082
70 4ZRN NAD 2.04082
71 4R1S NAP 2.04082
72 2NPX FAD 2.04082
73 5A04 NDP 2.04082
74 1EK6 UPG 2.04082
75 1EK6 NAI 2.04082
76 4ZRN UPG 2.04082
77 3AB1 FAD 2.04082
78 3SSO SAH 2.04082
79 3JQF NAP 2.08333
80 5K6A NAP 2.08333
81 3BMQ NAP 2.08333
82 1LUA NAP 2.09059
83 1MXH DHF 2.17391
84 1MXH NAP 2.17391
85 1C0I BE2 2.20386
86 1C0I FAD 2.20386
87 6F9Q NAD 2.20588
88 2VZ0 D64 2.23881
89 2VZ0 NAP 2.23881
90 1IY8 NAD 2.24719
91 3OZ2 FAD 2.267
92 1X1T NAD 2.30769
93 5YSS NAD 2.34375
94 5A1T NAI 2.34604
95 5A1T OXM 2.34604
96 2WSB NAD 2.3622
97 2Q46 NAP 2.37154
98 2PV7 NAD 2.38095
99 1H2B NAJ 2.38095
100 5TOW ADN 2.38095
101 5TOW NAI 2.38095
102 1V8B NAD 2.38095
103 4M52 M52 2.38095
104 1D4D FAD 2.38095
105 4M52 FAD 2.38095
106 1RJW ETF 2.38095
107 2A8X FAD 2.38095
108 2WET FAD 2.38095
109 4RSL FAD 2.38095
110 4B4U NAP 2.38095
111 5JCM NAD 2.38095
112 5JCM ISD 2.38095
113 5JCM FAD 2.38095
114 5LD5 NAD 2.38095
115 1DSS NAD 2.38095
116 5HXI FAD 2.38095
117 6C4M NAP 2.38095
118 2DBZ NAP 2.38095
119 5GUD NDP 2.38095
120 2XVF FAD 2.38095
121 5FI3 NAP 2.38095
122 5HXI 5HN 2.38095
123 6BII NAP 2.38095
124 5GUD 2IT 2.38095
125 2IXB NAD 2.38095
126 5XWC 8GL 2.38095
127 5XWC NAP 2.38095
128 5XWC 2IT 2.38095
129 2I3G NAP 2.38095
130 2YY7 NAD 2.38095
131 4YT4 FE9 2.38095
132 1F8G NAD 2.38095
133 3GMB FAD 2.38095
134 3UBM COA 2.38095
135 3SJ7 NDP 2.38095
136 1PJS NAD 2.38095
137 6H3O FAD 2.38095
138 5GUD CIT 2.38095
139 3KO8 NAD 2.38095
140 5K4W NAI 2.38095
141 5K4W THR 2.38095
142 3OND ADN 2.38095
143 3OND NAD 2.38095
144 6DNT NAD 2.38095
145 2IXB A2G 2.38095
146 5DMZ ADP 2.38095
147 2XZ9 PYR 2.38095
148 2CFC NAD 2.4
149 4NBU NAI 2.4
150 5OCM NAP 2.4055
151 5F5N NAD 2.42215
152 5EES NAP 2.42915
153 1C3V NDP 2.44898
154 1NM5 NAD 2.46305
155 2RH4 EMO 2.52708
156 6C4T NA7 2.66667
157 1U7T TDT 2.68199
158 1U7T NAD 2.68199
159 5ZI9 FLC 2.69231
160 3OID NDP 2.71318
161 2VHW NAI 2.72109
162 2WPF WPF 2.72109
163 2WPF FAD 2.72109
164 1J0X NAD 2.72109
165 3NYC FAD 2.72109
166 3NYC IAR 2.72109
167 1P0F NAP 2.72109
168 1U3U BNF 2.72109
169 1U3U NAD 2.72109
170 5BRT CH9 2.72109
171 4MIG G3F 2.72109
172 5OC1 FAD 2.72109
173 1GTE FAD 2.72109
174 6FHO FAD 2.72109
175 4NTD FAD 2.72109
176 3H9E NAD 2.72109
177 3ITJ FAD 2.72109
178 4Z0H NAD 2.72109
179 6F97 FAD 2.72109
180 4YNU FAD 2.72109
181 4YNU LGC 2.72109
182 2VTD LKM 2.72109
183 3L9W AMP 2.72109
184 1Q0H FOM 2.72109
185 1Q0H NDP 2.72109
186 3GF4 FAD 2.72109
187 3GF4 UPG 2.72109
188 5BRT FAD 2.72109
189 4WCX MET 2.72109
190 5MLR NAP 2.72109
191 5MLR GRQ 2.72109
192 5HV7 RBL 2.72109
193 4MDH NAD 2.72109
194 5HTX ADP 2.72109
195 5MDH NAD 2.72109
196 3L9W GSH 2.72109
197 3QJ4 FAD 2.72109
198 4TQG NDP 2.72109
199 1YB5 NAP 2.72109
200 3M89 GSP 2.72109
201 4YUW 4JU 2.72109
202 4KWI NAP 2.72109
203 4KWI 1TJ 2.72109
204 5TC4 NAD 2.72109
205 4YUW S4M 2.72109
206 3VYW SAM 2.72109
207 4W6Z 8ID 2.72109
208 4GLL NAD 2.72109
209 2JAC GSH 2.72727
210 2Q2V NAD 2.7451
211 3RJ5 NAD 2.75591
212 2D5A COA 2.77778
213 6GNA FAD 2.77778
214 5A96 GTP 2.81124
215 3ZV6 4HB 2.84698
216 3ZV6 NAD 2.84698
217 5U5N NAD 2.86738
218 2OOR NAD 2.87356
219 5OOH NAP 2.91262
220 5OOH 9ZZ 2.91262
221 5THQ NDP 2.94118
222 5T9E NAP 2.95203
223 5T9F NAP 2.95203
224 5T9F TYR 2.95203
225 5EOW FAD 2.96296
226 5WQP NAP 2.99145
227 3LZW FAD 3.01205
228 3LZW NAP 3.01205
229 1LK7 DER 3.05677
230 2Q0L NAP 3.06122
231 3ULK NDP 3.06122
232 2NVK NAP 3.06122
233 2IID PHE 3.06122
234 2IID FAD 3.06122
235 5EIN NAP 3.06122
236 2NVK FAD 3.06122
237 3GFB NAD 3.06122
238 2Q0L FAD 3.06122
239 3CGB FAD 3.06122
240 5UR0 NAD 3.06122
241 5JWC FAD 3.06122
242 2JHF NAD 3.06122
243 5GSN FAD 3.06122
244 5GSN NAP 3.06122
245 5GSN MMZ 3.06122
246 4UP3 FAD 3.06122
247 1GPE FAD 3.06122
248 1GQ2 NAP 3.06122
249 1T0S BML 3.06122
250 5HSA FAS 3.06122
251 3X0V FAD 3.06122
252 5KMS NAD 3.06122
253 2XVE FAD 3.06122
254 1RYD NDP 3.06122
255 1H6C NDP 3.06122
256 3KB6 NAD 3.06122
257 1ZH8 NAP 3.06122
258 4MO2 FDA 3.06122
259 4MO2 FAD 3.06122
260 1H6C SIN 3.06122
261 3A06 NDP 3.06122
262 1HYE NAP 3.06122
263 5KKA 6V0 3.06122
264 4DPL NAP 3.06122
265 4UP3 NDP 3.06122
266 3A06 FOM 3.06122
267 1R6D NAD 3.06122
268 5KMS FAD 3.06122
269 1R6D DAU 3.06122
270 1BXK NAD 3.06122
271 3WMX NAD 3.06122
272 1B8U NAD 3.06122
273 1B8U OAA 3.06122
274 4XFR CIT 3.06122
275 3LU1 NAD 3.06122
276 6GNC FAD 3.06122
277 4USR FAD 3.06122
278 6HL7 CP 3.06122
279 4OKD GLC GLC GLC 3.06122
280 4YAG NAI 3.11419
281 4RDI ATP 3.125
282 4RDH AMP 3.125
283 3ICC NAP 3.13725
284 1ZQ9 SAM 3.15789
285 4EA7 JB2 3.18182
286 4EA7 COA 3.18182
287 1RL4 BRR 3.19149
288 1HDR NAD 3.27869
289 1AE1 NAP 3.2967
290 3NOJ PYR 3.36134
291 1NVM NAD 3.40136
292 6AA8 NAD 3.40136
293 4ZVV NAD 3.40136
294 4ZVV GN0 3.40136
295 1N1G BCP 3.40136
296 5FJN BE2 3.40136
297 9LDB NAD 3.40136
298 5I39 FAD 3.40136
299 1LDM NAD 3.40136
300 1RSG FAD 3.40136
301 4XB2 NDP 3.40136
302 1KEV NDP 3.40136
303 5EZ7 FAD 3.40136
304 9LDT NAD 3.40136
305 2Z3Y F2N 3.40136
306 3ZNN FAD 3.40136
307 3ZNN 4WL 3.40136
308 1O6Z NAD 3.40136
309 5N6C NAD 3.40136
310 3B1J NAD 3.40136
311 2D2I NAP 3.40136
312 3B20 NAD 3.40136
313 2QRK AMP 3.40136
314 4JBI NDP 3.40136
315 4RQU NAD 3.40136
316 4XB2 HSE 3.40136
317 2CVQ NDP 3.40136
318 3GDN FAD 3.40136
319 3GDN HBX 3.40136
320 3C7A NAD 3.40136
321 3RC1 NAP 3.40136
322 4U7W NDP 3.40136
323 1TB4 PEJ 3.40136
324 3RC1 TLO 3.40136
325 4J1Q NDP 3.40136
326 5Z2F NAP 3.40136
327 5Z2L NDP 3.40136
328 4JJF FE9 3.40136
329 4RF2 NAP 3.40136
330 4B7X NAP 3.40136
331 4JJF N2I 3.40136
332 1H9A NAP 3.40136
333 1W8D NAP 3.40136
334 1W73 NAP 3.40136
335 1W6U NAP 3.40136
336 6BWL NAD 3.40136
337 1ZGS XMM 3.40136
338 5FJN FAD 3.40136
339 2RI1 GLP 3.40426
340 5GT9 NAP 3.42205
341 1GEE NAD 3.44828
342 1E3W NAD 3.44828
343 1NFQ NAI 3.46154
344 2AHR NAP 3.4749
345 3VPD BUA 3.55872
346 4D79 ATP 3.62319
347 5O4J 9KH 3.64964
348 5O4J SAH 3.64964
349 5O4J PJL 3.64964
350 4D3F NAP 3.7415
351 5BVA FAD 3.7415
352 2YVF FAD 3.7415
353 2YVF NAD 3.7415
354 1YY5 FAD 3.7415
355 1TDF NAP 3.7415
356 1TDF FAD 3.7415
357 5ZYN FAD 3.7415
358 3WGT FAD 3.7415
359 3WGT QSC 3.7415
360 2R4J FAD 3.7415
361 2R4J 13P 3.7415
362 4ZGS NAD 3.7415
363 4XYB NDP 3.7415
364 2C7G FAD 3.7415
365 1KOL NAD 3.7415
366 4AP3 FAD 3.7415
367 4AP3 NAP 3.7415
368 2C7G ODP 3.7415
369 4EIP FAD 3.7415
370 4D04 NAP 3.7415
371 4D04 FAD 3.7415
372 6F7L FAD 3.7415
373 2B9W FAD 3.7415
374 4EIP K2C 3.7415
375 1UWK URO 3.7415
376 1UWK NAD 3.7415
377 1PS9 FAD 3.7415
378 1NAA ABL 3.7415
379 1NAA 6FA 3.7415
380 1PS9 NAP 3.7415
381 5NA1 FAD 3.7415
382 4KP7 NAP 3.7415
383 3WQQ IB3 3.7415
384 3WQQ NDP 3.7415
385 4KP7 1UQ 3.7415
386 4L8F MTX 3.7415
387 1I2B USQ 3.7415
388 1I2B NAD 3.7415
389 1I2B UPG 3.7415
390 5IN4 GDP 3.7415
391 5IN4 6CK 3.7415
392 4YAC NAI 3.7415
393 5IN4 NAP 3.7415
394 6GAS FAD 3.7415
395 3V1U NAD 3.7415
396 5A07 GDP 3.7415
397 3ZVS MLI 3.75
398 5NM7 GLY 3.7594
399 4CJX NAP 3.76176
400 1JAY NAP 3.77358
401 2DT5 NAD 3.79147
402 1NE7 AGP 3.80623
403 5ZZ6 NAD 3.84615
404 5ZZ6 ADP 3.84615
405 2BQP GLC 3.84615
406 1GEG NAD 3.90625
407 1RYI GOA 3.9267
408 1RYI FAD 3.9267
409 1WMA NDP 3.98551
410 1WMA AB3 3.98551
411 4TSK NDP 4
412 2BDG PBZ 4.03587
413 2VVM FAD 4.0404
414 2VVL FAD 4.0404
415 1NYT NAP 4.05904
416 3VPH NAD 4.08163
417 3WBF NAP 4.08163
418 3FPZ AHZ 4.08163
419 3WBF API 4.08163
420 1YKJ FAD 4.08163
421 1YKJ PHB 4.08163
422 3VPH OXM 4.08163
423 1MO9 FAD 4.08163
424 1MO9 KPC 4.08163
425 5BUK FAD 4.08163
426 5MZI FYK 4.08163
427 5MZI FAD 4.08163
428 3K7M FAD 4.08163
429 2DKH FAD 4.08163
430 5Y77 FAD 4.08163
431 5MBX FAD 4.08163
432 5MBX SP5 4.08163
433 4YRY FAD 4.08163
434 2DKH 3HB 4.08163
435 1E1M FAD 4.08163
436 1E1M NAP 4.08163
437 4YRY NAD 4.08163
438 5YB7 ORN 4.08163
439 5X68 FAD 4.08163
440 5E4R NAP 4.08163
441 5YB7 FAD 4.08163
442 4Z24 FAD 4.08163
443 2B4R NAD 4.08163
444 2B4R AES 4.08163
445 5NUF NAD 4.08163
446 4IV9 FAD 4.08163
447 5NUE NAD 4.08163
448 5MQ6 NDP 4.08163
449 4AT0 FAD 4.08163
450 5XWV 8H6 4.08163
451 5XWV NDP 4.08163
452 2ZL4 ALA ALA ALA ALA 4.08163
453 2YG3 FAD 4.08163
454 2HIM ASP 4.08163
455 2NZ2 ASP 4.08163
456 3CV3 UDP 4.08163
457 4Y1B NAP 4.08163
458 3RK0 AMP 4.08163
459 4ITU NAI 4.08922
460 4ITU 1HS 4.08922
461 3AY6 BGC 4.08922
462 3AY6 NAI 4.08922
463 3BFF FPM 4.19847
464 3AFN NAP 4.26357
465 5L95 AMP 4.30108
466 1PN0 FAD 4.3609
467 1PN0 IPH 4.3609
468 1TKU 5RP 4.41176
469 1P77 ATR 4.41176
470 1A5Z NAD 4.42177
471 1GV0 NAD 4.42177
472 4ZCC FAD 4.42177
473 4ZCC NAI 4.42177
474 2GAG FAD 4.42177
475 1M2W NAD 4.42177
476 2GAG FOA 4.42177
477 2GAG NAD 4.42177
478 1LJ8 NAD 4.42177
479 5O9F 9ON 4.42177
480 5O9F NAD 4.42177
481 5NMX NAP 4.42177
482 5J7X FAD 4.42177
483 3LXD FAD 4.42177
484 5TTJ FAD 4.42177
485 4PLG NAI 4.42177
486 4PLG OXM 4.42177
487 4XDZ NDP 4.42177
488 4GKV NAD 4.42177
489 5JY6 NAD 4.42177
490 1I8T FAD 4.42177
491 3NKS FAD 4.42177
492 4RPL FAD 4.42177
493 4RPL 3UC 4.42177
494 4KQW NAP 4.42177
495 4TM3 FAD 4.42177
496 5EB4 FAD 4.42177
497 1VDC FAD 4.42177
498 5NMX FAD 4.42177
499 2FR1 NDP 4.42177
500 1COY FAD 4.42177
501 1COY AND 4.42177
502 1X14 NAD 4.42177
503 2C29 NAP 4.42177
504 1V6A TRE 4.42177
505 4BVA NDP 4.42177
506 1SB8 UD2 4.42177
507 1SB8 NAD 4.42177
508 1EQ2 NAP 4.42177
509 5NII FAD 4.42177
510 2C29 DQH 4.42177
511 4BVA T3 4.42177
512 4Z94 ATP 4.42177
513 4IDC NDP 4.42177
514 4IDC 1XX 4.42177
515 2X6T NAP 4.42177
516 1RKX NAD 4.42177
517 1PZG A3D 4.42177
518 5OFW 9TW 4.4843
519 1UAY ADN 4.54545
520 2AG8 NAP 4.56274
521 1O8B ABF 4.56621
522 5XH2 NPO 4.58015
523 4E13 NAD 4.59364
524 1G0N NDP 4.59364
525 1G0N PHH 4.59364
526 2V6G NAP 4.67033
527 2PK3 A2R 4.6729
528 2DKN NAI 4.70588
529 6C4N NAP 4.7619
530 2CDC XYP 4.7619
531 2CDC XYS 4.7619
532 5M67 NAD 4.7619
533 5M67 ADE 4.7619
534 5M67 3D1 4.7619
535 5G3U FDA 4.7619
536 1EZ4 NAD 4.7619
537 5G3U ITW 4.7619
538 4E5N NAD 4.7619
539 5KOX RFP 4.7619
540 5KOX FAD 4.7619
541 5ZBC FAD 4.7619
542 4HA6 FAD 4.7619
543 2CDC NAP 4.7619
544 3HDY GDU 4.7619
545 3HDY FDA 4.7619
546 1E5Q NDP 4.7619
547 3HDY FAD 4.7619
548 1K3T BRZ 4.7619
549 4PLT NAI 4.7619
550 4PLT OXM 4.7619
551 3Q9T FAY 4.7619
552 1U1I NAD 4.7619
553 5L4S NAP 4.7619
554 5L4S 6KX 4.7619
555 2PZM NAD 4.7619
556 2PZM UDP 4.7619
557 1REO FAD 4.7619
558 1ORR NAD 4.7619
559 4USQ FAD 4.7619
560 1JQ3 AAT 4.7619
561 3ORF NAD 4.78088
562 3H8V ATP 4.79452
563 4URF NAD 4.83871
564 5T2U NAP 4.83871
565 1RP0 AHZ 4.92958
566 1LES GLC FRU 4.97238
567 3SJU NDP 5.01792
568 1LTH NAD 5.10204
569 4YKG NAD 5.10204
570 4YKG FAD 5.10204
571 3T31 DCQ 5.10204
572 3T31 FAD 5.10204
573 2HJR APR 5.10204
574 2RAB NAD 5.10204
575 2RAB FAD 5.10204
576 1YQZ FAD 5.10204
577 3I6I NDP 5.10204
578 5ZI2 ADP 5.10204
579 3CIF NAD 5.10204
580 1O0S NAI 5.10204
581 5ZI2 NAD 5.10204
582 5AOV NAP 5.10204
583 4KVL PLM 5.10204
584 2GCG NDP 5.10204
585 1SC6 NAD 5.10204
586 2GLX NDP 5.10204
587 5KVS NAP 5.10204
588 1E7S NAP 5.10204
589 1HDG NAD 5.10204
590 3DAG FEG 5.10204
591 2EXX NAP 5.10204
592 3IHB GLU 5.10204
593 3A4V NAD 5.10204
594 3A4V PYR 5.10204
595 1FL2 FAD 5.10204
596 2IZ1 ATR 5.10204
597 4JDR FAD 5.10204
598 3CIF G3H 5.10204
599 5KVS 6XR 5.10204
600 5N53 8NB 5.12821
601 1VL0 NAI 5.13699
602 2CUL FAD 5.17241
603 3H4V NAP 5.20833
604 3H4V DVP 5.20833
605 5D4V SAH 5.22388
606 3NUG NAD 5.26316
607 2IMG MLT 5.29801
608 4OSP NAP 5.32319
609 4CQM NAP 5.32787
610 2BD0 NAP 5.32787
611 4JK3 NAD 5.40541
612 4IN9 SER TRP PHE PRO 5.42169
613 1HKU NAD 5.44218
614 6CEP NAD 5.44218
615 6CEP OXM 5.44218
616 4J36 1HR 5.44218
617 4J36 FAD 5.44218
618 1GR0 NAD 5.44218
619 1CF2 NAP 5.44218
620 4XQC 13D 5.44218
621 3QV1 NAD 5.44218
622 2Y6Q I7T 5.44218
623 3BAZ NAP 5.44218
624 1E3I CXF 5.44218
625 1PGP 6PG 5.44218
626 1GAD NAD 5.44218
627 5N0J FAD 5.44218
628 5TUK FAD 5.44218
629 1QMG APX 5.44218
630 2Y6Q FAD 5.44218
631 1Q19 SSC 5.44218
632 1YKF NAP 5.44218
633 1RPN NDP 5.44218
634 1Y1P NMN AMP PO4 5.44218
635 1UP7 NAD 5.44218
636 4PIV NDP 5.44218
637 1GY8 NAD 5.44218
638 4XQC NAD 5.44218
639 1KYQ NAD 5.47445
640 1DRV A3D 5.49451
641 1ZK4 NAP 5.57769
642 1ZK4 AC0 5.57769
643 4XZ3 COA 5.65217
644 3WXB NDP 5.73477
645 3CGD FAD 5.78231
646 5TUF TDC 5.78231
647 3CGD COA 5.78231
648 3CGD NAD 5.78231
649 4X9M FAD 5.78231
650 5Z20 NAI 5.78231
651 2VYN NAD 5.78231
652 5TUF FAD 5.78231
653 1RM4 NDP 5.78231
654 2QZZ EMF 5.78231
655 2QZZ NAP 5.78231
656 1VI2 NAD 5.78231
657 1LC3 NAD 5.78231
658 1V35 NAI 5.78231
659 4J4H NAI 5.79151
660 4J4H 1J1 5.79151
661 3NGL NAP 5.7971
662 4YSX FAD 5.85106
663 3WD6 GSH 5.85938
664 1NPD NAD 5.90278
665 1N5D NDP 5.90278
666 3QWI CUE 5.92593
667 3QWI NAP 5.92593
668 3Q3C NAD 6.02007
669 1XKQ NDP 6.07143
670 2EV9 SKM 6.08365
671 2EV9 NAP 6.08365
672 1XG5 NAP 6.09319
673 1WDK NAD 6.12245
674 1ZK7 FAD 6.12245
675 5U8U FAD 6.12245
676 3LAD FAD 6.12245
677 1LLU NAD 6.12245
678 3E1T FAD 6.12245
679 4JNA FAD 6.12245
680 4U8P FDA 6.12245
681 4U8P UDP 6.12245
682 4BJZ P3A 6.12245
683 4BJZ FAD 6.12245
684 2B5W NAP 6.12245
685 3WLE NAD 6.12245
686 1YS4 NAP 6.12245
687 2Q1W NAD 6.12245
688 2JB2 PHE 6.12245
689 2JB2 FAD 6.12245
690 5MSO NAP 6.12245
691 3ISN EDM 6.12245
692 5YEC ATP 6.12245
693 3GVL SLB SIA 6.12245
694 4BGB ADP 6.12245
695 5EJ2 NAD 6.16883
696 3A28 NAD 6.20155
697 1Z0N BCD 6.25
698 4NBT NAD 6.25
699 1P19 IMP 6.33484
700 5OJL TXP 6.37584
701 4EDF UPG 6.46258
702 5U5G NAP 6.46258
703 6ER9 FAD 6.46258
704 6ER9 NAP 6.46258
705 3UCL NAP 6.46258
706 3UCL CYH 6.46258
707 3UCL FAD 6.46258
708 3F8D FAD 6.46258
709 3QVP FAD 6.46258
710 5WGR FAD 6.46258
711 4DSG FAD 6.46258
712 4DSG UDP 6.46258
713 4Y9D NAI 6.46258
714 5YAP NAI 6.46258
715 5YAP 8S0 6.46258
716 2GSD NAD 6.46258
717 2EG5 SAH 6.46258
718 2NAD NAD 6.46258
719 5FEU NAP 6.52921
720 2CVZ NDP 6.57439
721 1FK8 NAD 6.61479
722 1JNR FAD 6.66667
723 4D42 NAP 6.73759
724 4D42 W0I 6.73759
725 6F3N NAD 6.80272
726 6F3N ADN 6.80272
727 3NJ4 NAD 6.80272
728 3NJ4 AFX 6.80272
729 1GZ4 ATP 6.80272
730 3KLJ FAD 6.80272
731 5GZ6 NDP 6.80272
732 5GZ6 7C3 6.80272
733 1Q1R FAD 6.80272
734 3CMC NAD 6.80272
735 6F3M NAD 6.80272
736 4C3Y FAD 6.80272
737 5DF1 NAP 6.80272
738 5DF1 58X 6.80272
739 5O98 NAP 6.80272
740 4C3Y ANB 6.80272
741 5KQA GSH 6.81818
742 6CI9 NAP 6.94981
743 1J5P NAD 7.11462
744 1VL8 NAP 7.11611
745 4XDY NAI 7.14286
746 3AD8 FAD 7.14286
747 3AD8 PYC 7.14286
748 3AD8 NAD 7.14286
749 3QFA FAD 7.14286
750 4MP8 MLI 7.14286
751 4MP8 NAD 7.14286
752 4B63 ORN 7.14286
753 4B63 NAP 7.14286
754 4B63 FAD 7.14286
755 3S5W NAP 7.14286
756 2DTX BMA 7.14286
757 3S5W FAD 7.14286
758 1Z45 NAD 7.14286
759 4O1M NAD 7.14286
760 5J60 FAD 7.14286
761 2F1K NAP 7.16846
762 1WP4 NDP 7.26644
763 2JAH NDP 7.28745
764 4B9E FAH 7.30897
765 4XYM COA 7.32759
766 1VL1 CIT 7.32759
767 1EDO NAP 7.37705
768 5FFF NAP 7.393
769 5FFF 5XC 7.393
770 3O26 NDP 7.3955
771 1NNU NAD 7.42358
772 1NNU TCT 7.42358
773 1DLJ NAI 7.48299
774 1DLJ UGA 7.48299
775 3AYI FAD 7.48299
776 3AYI HCI 7.48299
777 3AXB FAD 7.48299
778 3AXB PRO 7.48299
779 2E5V FAD 7.48299
780 3G5S FAD 7.48299
781 6GAR FAD 7.48299
782 2IVD FAD 7.48299
783 1SAY PYR 7.48299
784 3ETG GTP 7.48299
785 3ETG GLU 7.48299
786 2GVC FAD 7.48299
787 2GV8 FAD 7.48299
788 1DIG NAP 7.48299
789 2GV8 NDP 7.48299
790 1VQW FAD 7.48299
791 5Y1G NAD 7.48299
792 5Y1G AKB 7.48299
793 1DIG L37 7.48299
794 6EL3 NAP 7.48299
795 3ETG NDP 7.48299
796 4O0L NDP 7.63636
797 5O42 9JW 7.66423
798 5O42 BGC 7.66423
799 5O42 NAD 7.66423
800 2JAP NDP 7.69231
801 6FP4 E1T 7.82313
802 6FP4 FAD 7.82313
803 3ICT ADP 7.82313
804 3ICS ADP 7.82313
805 2CDU FAD 7.82313
806 2CDU ADP 7.82313
807 5BJX NAD 7.82313
808 3ICT FAD 7.82313
809 3ICS FAD 7.82313
810 3ICR FAD 7.82313
811 5BJX UDP 7.82313
812 3G2O SAM 7.82313
813 2I7C AAT 7.82313
814 2BKA NDP 7.85124
815 2EWM NAD 8.03213
816 2DC1 NAD 8.05085
817 2AE2 PTO 8.07692
818 2AE2 NAP 8.07692
819 3OJO NAD 8.16327
820 5MIT NAP 8.16327
821 5MIT FAD 8.16327
822 4GUS FAD 8.16327
823 4GUT FAD 8.16327
824 4FWE FAD 8.16327
825 1O94 ADP 8.16327
826 4HSU FAD 8.16327
827 1DJN ADP 8.16327
828 1OMO NAD 8.16327
829 5VN0 NAI 8.16327
830 5VN0 FAD 8.16327
831 1PL6 572 8.16327
832 1PL6 NAD 8.16327
833 1R37 NAD 8.16327
834 1UDB UFG 8.16327
835 1UDB NAD 8.16327
836 1Y8Q ATP 8.16327
837 4D7E FAD 8.16327
838 2EB5 OXL 8.2397
839 3WV8 ATP 8.25688
840 2BGM NAJ 8.27338
841 2Q7V FAD 8.30769
842 1I36 NAP 8.33333
843 2NV2 GLN 8.33333
844 1GZ6 NAI 8.46395
845 5TWB FAD 8.5034
846 4OPC PGT 8.5034
847 1T26 NAI 8.5034
848 1T26 GBD 8.5034
849 4OPC FDA 8.5034
850 3C1O NAP 8.5034
851 5K0A FAD 8.5034
852 2ZXI FAD 8.5034
853 3HB5 NAP 8.5034
854 2GN4 NDP 8.5034
855 2GN4 UD1 8.5034
856 1KEW NAD 8.5034
857 1KEW TYD 8.5034
858 5TS5 FAD 8.5034
859 1OBB NAD 8.5034
860 3V1Y NAD 8.60534
861 4FN4 NAD 8.66142
862 1MV8 NAD 8.7156
863 2HK9 NAP 8.72727
864 2HK9 ATR 8.72727
865 2GMH FAD 8.84354
866 1X87 NAD 8.84354
867 5OF1 SAL 9.04762
868 2YVJ NAI 9.17431
869 2YVJ FAD 9.17431
870 5JE8 NAD 9.18367
871 1BZL GCG 9.18367
872 1BZL FAD 9.18367
873 2HQM FAD 9.18367
874 1C1X NAD 9.18367
875 4CNK FAD 9.18367
876 3FG2 FAD 9.18367
877 1BW9 NAD 9.18367
878 1BXG NAD 9.18367
879 1O5I NAD 9.18367
880 1VGR COA 9.18367
881 4KOA NDP 9.18367
882 2RGJ FAD 9.45274
883 5XVH NAP 9.52381
884 5YU3 PRO 9.52381
885 5YU3 NAD 9.52381
886 4C2G ALA ALA ALA ALA 9.52381
887 3B12 FAH 9.52381
888 1FWV SGA MAG FUC 9.70149
889 3TN7 NJP 9.72763
890 4EMI NAD 9.86395
891 6A3J SOE 9.86395
892 4EMJ FAD 9.86395
893 2A92 NAI 9.86395
894 6A3J NAI 9.86395
895 4HXY NDP 9.86395
896 4EMI FAD 9.86395
897 2BKX F6R 9.91736
898 1WPQ NAD 10.0287
899 3VZS NAP 10.1167
900 3VZS CAA 10.1167
901 5ODQ FAD 10.2041
902 1FEC FAD 10.2041
903 1SOW NAD 10.2041
904 4QED NAP 10.4839
905 1Z82 NDP 10.5442
906 5J5Z FAD 10.5442
907 5UAV TFB 10.5442
908 5UAV NDP 10.5442
909 2RGH FAD 10.5442
910 2GZ3 NAP 10.5442
911 1N7G NDP 10.5442
912 1N7G GDR 10.5442
913 1QXA GLY GLY GLY 10.6383
914 4URS C2E 10.6383
915 4G5H NAP 10.7438
916 4G5H UD7 10.7438
917 4II2 ATP 10.8434
918 1XHC FAD 10.8844
919 2RGO FAD 10.8844
920 2YYY NAP 10.8844
921 1VJT NAD 10.8844
922 2F5Z FAD 10.9375
923 2AOT SAH 10.9589
924 2O66 FLC 11.1111
925 4OM8 NAD 11.2245
926 5W3K NDP 11.2245
927 5W3K 9TY 11.2245
928 1QO8 FAD 11.2245
929 1RM0 D6P 11.2245
930 1RM0 NAI 11.2245
931 5OVL NAP 11.2245
932 5JCA FAD 11.2676
933 5JCA NDP 11.2676
934 3NZ1 3NY 11.4943
935 1UXG NAD 11.5646
936 1UXG FUM 11.5646
937 2QA1 FAD 11.5646
938 3O9Z NAD 11.5646
939 3O9Z AKG 11.5646
940 3GLC R5P 11.5646
941 5H81 NAP 11.5681
942 5X9D 80F 11.9048
943 1CER NAD 11.9048
944 3FPF TNA 11.9048
945 3FPF MTA 11.9048
946 1LSS NAD 12.1429
947 4MOP 2H5 12.2449
948 4J56 FAD 12.2449
949 2DFV NAD 12.2449
950 1Q7B NAP 12.2951
951 5OVK NDP 12.5
952 1GUZ NAD 12.585
953 1J49 NAD 12.585
954 5BSH PRO 12.6354
955 1H5Q NAP 12.8302
956 1MUU NAD 12.9252
957 2ZJ1 ARJ 12.9252
958 2ZJ1 NAD 12.9252
959 3L4S NAD 12.9252
960 3L4S 3PG 12.9252
961 3H5N ATP 12.9252
962 3HAD NAD 12.987
963 1M0S CIT 13.242
964 3B1F NAD 13.2653
965 1GET FAD 13.2653
966 1GET NAP 13.2653
967 3FWN ATR 13.2653
968 4L8V NAP 13.2653
969 5N2I NAP 13.3621
970 2NU8 COA 13.4021
971 5Z21 NAI 13.6054
972 1HYH NAD 13.9456
973 1EBF NAD 13.9456
974 1KJ8 GAR 13.9456
975 2VT3 ATP 13.9535
976 3Q9N COA 14.1844
977 1VKF CIT 14.3617
978 1NVT NAP 14.6259
979 1E6E FAD 14.8438
980 1V59 NAD 14.966
981 1V59 FAD 14.966
982 3GGO ENO 14.966
983 3GGO NAI 14.966
984 3KIF GDL 15.0943
985 2G5C NAD 15.3025
986 3CTY FAD 15.3061
987 1XHL NDP 15.4882
988 5CAE SIN 15.6463
989 1H82 GZZ 15.6463
990 5CAE COA 15.6463
991 1H82 FAD 15.6463
992 1YQD NAP 15.6463
993 1VKO NAD 16.6667
994 3ABI NAD 17.0068
995 5T2Y 753 17.1717
996 1F8F NAD 17.6871
997 3SQP FAD 18.0272
998 3NT6 FAD 18.7075
999 3NTA FAD 19.0476
1000 3NTD FAD 19.7279
1001 3RNM FAD 20.6897
1002 4OOE NDP 20.7483
1003 4OOE FOM 20.7483
1004 5G4L NDP 21.6783
1005 3UOY NAP 21.7687
1006 3UOY FAD 21.7687
1007 2HMT NAI 32.6389
Pocket No.: 2; Query (leader) PDB : 4YCA; Ligand: NDP; Similar sites found with APoc: 41
This union binding pocket(no: 2) in the query (biounit: 4yca.bio1) has 28 residues
No: Leader PDB Ligand Sequence Similarity
1 5TKL G3H 2.38095
2 1EYQ NAR 2.7027
3 5FPE 3TR 2.72109
4 5CX8 TG6 2.72109
5 6BR7 BEF 3.00752
6 5YLF BGC 3.06122
7 4BWL MN9 3.06122
8 1NXJ TLA 3.27869
9 1JLV GSH 3.34928
10 1SJD NPG 3.40136
11 3LN9 FLC 3.59712
12 2J5V PCA 3.7415
13 1EI6 PPF 3.7415