Receptor
PDB id Resolution Class Description Source Keywords
4YRL 2.3 Å EC: 6.1.1.21 CRYSTAL STRUCTURE OF T. CRUZI HISTIDYL-TRNA SYNTHETASE IN CO 4-(METHYLSULFANYL)ANILINE (CHEM 262) TRYPANOSOMA CRUZI (STRAIN CL BRENER) LIGASE AMINOACYL-TRNA SYNTHETASE AARS HISRS TRYPANOSOMA PROTEIN-INHIBITOR COMPLEX LIGASE-LIGASE INHIBITOR COMPLEX
Ref.: A BINDING HOTSPOT IN TRYPANOSOMA CRUZI HISTIDYL-TRN SYNTHETASE REVEALED BY FRAGMENT-BASED CRYSTALLOGRAP COCKTAIL SCREENS. ACTA CRYSTALLOGR. D BIOL. V. 71 1684 2015 CRYSTALLOGR.
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SO4 A:507;
A:505;
A:506;
 Invalid;
Invalid;
Invalid;
 none;
none;
none;
 submit data
96.063 O4 S [O-]S...
DMS A:508;
 Invalid;
 none;
 submit data
78.133 C2 H6 O S CS(=O...
EDO A:503;
A:504;
 Invalid;
Invalid;
 none;
none;
 submit data
62.068 C2 H6 O2 C(CO)...
4JM A:502;
 Valid;
 none;
 submit data
139.218 C7 H9 N S CSc1c...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4YRI 2 Å EC: 6.1.1.21 CRYSTAL STRUCTURE OF T. CRUZI HISTIDYL-TRNA SYNTHETASE IN CO 1-(3-BROMOPHENYL)METHANAMINE (CHEM 166) TRYPANOSOMA CRUZI (STRAIN CL BRENER) LIGASE AMINOACYL-TRNA SYNTHETASE AARS HISRS TRYPANOSOMA PROTEIN-INHIBITOR COMPLEX LIGASE-LIGASE INHIBITOR COMPLEX
Ref.: A BINDING HOTSPOT IN TRYPANOSOMA CRUZI HISTIDYL-TRN SYNTHETASE REVEALED BY FRAGMENT-BASED CRYSTALLOGRAP COCKTAIL SCREENS. ACTA CRYSTALLOGR. D BIOL. V. 71 1684 2015 CRYSTALLOGR.
Members (16)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4YRI - 4JH C7 H8 Br N c1cc(cc(c1....
2 4YRF - 4HS C5 H4 Br N O C1=CC(=O)N....
3 4YRP - PZH C7 H8 Br N c1cc(ccc1C....
4 4YRC - 0P6 C9 H8 N2 O c1cc2ccc(n....
5 4YRJ - 4JJ C6 H7 Cl N2 c1cc(c(cc1....
6 4YRQ - 4JQ C9 H7 N O2 c1cc2c(cc1....
7 4YP0 - 5IQ C9 H8 N2 c1cc2cnccc....
8 4YRM - 282 C6 H7 N O COc1cccnc1
9 4YRL - 4JM C7 H9 N S CSc1ccc(cc....
10 4YPF - 4FS C9 H8 N2 c1ccc2c(c1....
11 4YRE - 4HR C7 H7 Br O c1ccc(c(c1....
12 4YRN - 4JN C5 H5 Br N2 c1cc(ncc1N....
13 4YRK - 4JL C7 H7 Cl O c1cc(ccc1C....
14 4YRO - 4JO C6 H7 Br N2 Cc1c(ccc(n....
15 4YRR - 691 C11 H10 N2 O CC(=O)Nc1c....
16 4YRG - 4HU C6 H6 Br N O c1cc(nc(c1....
70% Homology Family (16)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4YRI - 4JH C7 H8 Br N c1cc(cc(c1....
2 4YRF - 4HS C5 H4 Br N O C1=CC(=O)N....
3 4YRP - PZH C7 H8 Br N c1cc(ccc1C....
4 4YRC - 0P6 C9 H8 N2 O c1cc2ccc(n....
5 4YRJ - 4JJ C6 H7 Cl N2 c1cc(c(cc1....
6 4YRQ - 4JQ C9 H7 N O2 c1cc2c(cc1....
7 4YP0 - 5IQ C9 H8 N2 c1cc2cnccc....
8 4YRM - 282 C6 H7 N O COc1cccnc1
9 4YRL - 4JM C7 H9 N S CSc1ccc(cc....
10 4YPF - 4FS C9 H8 N2 c1ccc2c(c1....
11 4YRE - 4HR C7 H7 Br O c1ccc(c(c1....
12 4YRN - 4JN C5 H5 Br N2 c1cc(ncc1N....
13 4YRK - 4JL C7 H7 Cl O c1cc(ccc1C....
14 4YRO - 4JO C6 H7 Br N2 Cc1c(ccc(n....
15 4YRR - 691 C11 H10 N2 O CC(=O)Nc1c....
16 4YRG - 4HU C6 H6 Br N O c1cc(nc(c1....
50% Homology Family (16)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4YRI - 4JH C7 H8 Br N c1cc(cc(c1....
2 4YRF - 4HS C5 H4 Br N O C1=CC(=O)N....
3 4YRP - PZH C7 H8 Br N c1cc(ccc1C....
4 4YRC - 0P6 C9 H8 N2 O c1cc2ccc(n....
5 4YRJ - 4JJ C6 H7 Cl N2 c1cc(c(cc1....
6 4YRQ - 4JQ C9 H7 N O2 c1cc2c(cc1....
7 4YP0 - 5IQ C9 H8 N2 c1cc2cnccc....
8 4YRM - 282 C6 H7 N O COc1cccnc1
9 4YRL - 4JM C7 H9 N S CSc1ccc(cc....
10 4YPF - 4FS C9 H8 N2 c1ccc2c(c1....
11 4YRE - 4HR C7 H7 Br O c1ccc(c(c1....
12 4YRN - 4JN C5 H5 Br N2 c1cc(ncc1N....
13 4YRK - 4JL C7 H7 Cl O c1cc(ccc1C....
14 4YRO - 4JO C6 H7 Br N2 Cc1c(ccc(n....
15 4YRR - 691 C11 H10 N2 O CC(=O)Nc1c....
16 4YRG - 4HU C6 H6 Br N O c1cc(nc(c1....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 4JM; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 4JM 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: 4JM; Similar ligands found: 924
No: Ligand Similarity coefficient
1 4VP 0.9961
2 HBA 0.9906
3 4JL 0.9872
4 PHB 0.9861
5 FBA 0.9792
6 C2B 0.9756
7 H8N 0.9735
8 DHR 0.9692
9 RBJ 0.9685
10 AMC 0.9672
11 PBZ 0.9663
12 HBD 0.9662
13 BP9 0.9658
14 4CH 0.9657
15 AEF 0.9652
16 BML 0.9639
17 AC6 0.9633
18 MZW 0.9629
19 4JU 0.9620
20 PAB 0.9618
21 4HS 0.9618
22 IOL 0.9618
23 SYN 0.9611
24 NPO 0.9600
25 YRL 0.9595
26 4FA 0.9584
27 717 0.9570
28 826 0.9565
29 4JN 0.9564
30 PYJ 0.9563
31 P72 0.9554
32 2MH 0.9544
33 HMH 0.9536
34 1Y6 0.9535
35 KOJ 0.9532
36 4MA 0.9530
37 24B 0.9529
38 HMU 0.9527
39 PXY 0.9511
40 PCR 0.9504
41 ABN 0.9494
42 174 0.9493
43 1PT 0.9491
44 ZZT 0.9486
45 4XR 0.9480
46 FYU 0.9472
47 9CL 0.9463
48 PBC 0.9459
49 25R 0.9457
50 PEA 0.9455
51 HBX 0.9455
52 HQE 0.9455
53 LG4 0.9455
54 Z82 0.9452
55 FAN 0.9451
56 PZM 0.9451
57 8H8 0.9448
58 HX3 0.9427
59 CXF 0.9422
60 1MR 0.9420
61 NBE 0.9418
62 HY1 0.9415
63 BEN 0.9414
64 OHG 0.9414
65 BEZ 0.9409
66 DA1 0.9409
67 BAM 0.9404
68 PEL 0.9404
69 FPI 0.9401
70 FPN 0.9397
71 PLQ 0.9394
72 H4N 0.9393
73 FK1 0.9392
74 JAE 0.9392
75 NSP 0.9387
76 AC0 0.9384
77 TH7 0.9381
78 LDP 0.9380
79 ES9 0.9378
80 8NY 0.9375
81 282 0.9367
82 11S 0.9365
83 PYF 0.9362
84 UNU 0.9347
85 BZ3 0.9344
86 B24 0.9336
87 R2B 0.9336
88 APY 0.9334
89 NIO 0.9331
90 NCA 0.9331
91 PY7 0.9330
92 E5X 0.9329
93 27Y 0.9326
94 ANN 0.9325
95 IDH 0.9320
96 NTN 0.9316
97 GLC 0.9316
98 5NU 0.9314
99 AHR 0.9312
100 VGD 0.9310
101 5OB 0.9309
102 CLW 0.9308
103 MWJ 0.9306
104 CEE 0.9306
105 BHA 0.9301
106 5MI 0.9299
107 SS1 0.9298
108 4BZ 0.9297
109 OTR 0.9297
110 36R 0.9295
111 BZX 0.9293
112 6PC 0.9291
113 LDU 0.9288
114 PNZ 0.9287
115 42J 0.9286
116 HC4 0.9285
117 93K 0.9283
118 9X7 0.9281
119 2MI 0.9279
120 5VM 0.9279
121 K2T 0.9278
122 ORN 0.9278
123 IPB 0.9277
124 5XC 0.9274
125 FBB 0.9274
126 7WG 0.9272
127 ES2 0.9268
128 PZA 0.9267
129 JZ3 0.9266
130 SN4 0.9264
131 5MB 0.9262
132 DHB 0.9260
133 1P8 0.9258
134 BR9 0.9258
135 INO 0.9257
136 JZ5 0.9256
137 4J8 0.9256
138 FQI 0.9253
139 FP1 0.9251
140 XIY 0.9250
141 HDH 0.9249
142 ET2 0.9249
143 H42 0.9247
144 MET 0.9245
145 M58 0.9244
146 F60 0.9243
147 5H1 0.9242
148 2K4 0.9242
149 4HO 0.9239
150 4P5 0.9238
151 NOJ 0.9236
152 14O 0.9236
153 MR1 0.9235
154 TSU 0.9235
155 9TW 0.9233
156 6AI 0.9232
157 BNS 0.9232
158 IT2 0.9231
159 NBZ 0.9230
160 ABV 0.9229
161 2LP 0.9229
162 RSO 0.9226
163 DFB 0.9225
164 1M2 0.9224
165 MNN 0.9223
166 4JJ 0.9222
167 F9Y 0.9221
168 IHB 0.9220
169 4JO 0.9219
170 1DH 0.9217
171 HSM 0.9217
172 4NM 0.9216
173 NNO 0.9216
174 5JC 0.9216
175 CHB 0.9214
176 CFI 0.9214
177 BPN 0.9214
178 URF 0.9214
179 P9P 0.9213
180 JZ4 0.9212
181 4NC 0.9211
182 270 0.9211
183 AX7 0.9211
184 4CL 0.9210
185 FA0 0.9210
186 SAN 0.9210
187 WBU 0.9210
188 YCP 0.9209
189 DOB 0.9209
190 XM0 0.9207
191 MCT 0.9206
192 ISZ 0.9206
193 IUR 0.9205
194 TYL 0.9204
195 SS2 0.9204
196 FHB 0.9202
197 NK 0.9200
198 2BG 0.9200
199 TH0 0.9200
200 4A3 0.9196
201 FPY 0.9194
202 JZ2 0.9192
203 0R0 0.9191
204 3HM 0.9191
205 GUA 0.9190
206 VGL 0.9189
207 QSB 0.9185
208 AMH 0.9185
209 OAA 0.9184
210 HGW 0.9183
211 BE7 0.9182
212 SAL 0.9181
213 5CU 0.9179
214 MZG 0.9178
215 XRG 0.9177
216 261 0.9177
217 HGQ 0.9176
218 1AB 0.9176
219 JZ1 0.9175
220 JA8 0.9174
221 2HO 0.9174
222 5MH 0.9167
223 286 0.9167
224 FBM 0.9164
225 TDR 0.9164
226 4ZA 0.9164
227 A1U 0.9163
228 1MC 0.9161
229 3DM 0.9161
230 IDM 0.9160
231 BHO 0.9156
232 OK7 0.9156
233 XYP 0.9154
234 4M0 0.9151
235 69O 0.9150
236 MLT 0.9148
237 2AC 0.9146
238 3SK 0.9144
239 LMR 0.9144
240 XUL 0.9143
241 YPN 0.9143
242 KMT 0.9142
243 BE2 0.9141
244 3U4 0.9136
245 JZ7 0.9135
246 I1E 0.9134
247 QSC 0.9133
248 5UC 0.9132
249 VNJ 0.9132
250 RIB 0.9131
251 XX2 0.9130
252 25T 0.9129
253 MYJ 0.9126
254 14J 0.9124
255 QOS 0.9124
256 PIH 0.9122
257 XYD 0.9120
258 Y8I 0.9120
259 GLU 0.9117
260 DTU 0.9116
261 ES5 0.9116
262 NYL 0.9115
263 BSX 0.9114
264 2YU 0.9112
265 PHU 0.9111
266 ICP 0.9110
267 XBZ 0.9110
268 R8S 0.9110
269 P92 0.9109
270 23A 0.9109
271 4WL 0.9108
272 GXE 0.9108
273 PKU 0.9108
274 XBT 0.9107
275 M4T 0.9107
276 TLD 0.9107
277 4FS 0.9106
278 23W 0.9102
279 HDA 0.9098
280 HSE 0.9097
281 259 0.9096
282 03V 0.9095
283 NIZ 0.9094
284 CYS 0.9094
285 43M 0.9093
286 NVI 0.9093
287 MAE 0.9091
288 GAL 0.9090
289 34A 0.9090
290 NF3 0.9088
291 AEG 0.9088
292 PYD 0.9086
293 54D 0.9083
294 1DJ 0.9082
295 2AQ 0.9080
296 2A9 0.9079
297 6NT 0.9078
298 F9P 0.9076
299 258 0.9075
300 HHN 0.9075
301 4ZE 0.9074
302 BNF 0.9073
303 DEN 0.9072
304 271 0.9071
305 LXC 0.9070
306 COU 0.9066
307 ODO 0.9066
308 TMZ 0.9062
309 HVQ 0.9062
310 MRY 0.9060
311 DGJ 0.9060
312 2MP 0.9060
313 2FY 0.9059
314 3XX 0.9059
315 EDG 0.9058
316 F81 0.9057
317 3A9 0.9056
318 XQ0 0.9056
319 TTO 0.9055
320 P3K 0.9051
321 ASO 0.9050
322 275 0.9050
323 SMV 0.9046
324 JAW 0.9045
325 TM7 0.9045
326 1F1 0.9043
327 TZE 0.9043
328 OCH 0.9042
329 CXL 0.9042
330 TPA 0.9041
331 BVC 0.9037
332 AMS 0.9037
333 MWM 0.9037
334 4XX 0.9035
335 I3A 0.9034
336 QWN 0.9032
337 2ZM 0.9032
338 BDP 0.9032
339 JFJ 0.9031
340 UGC 0.9031
341 82I 0.9030
342 AAS 0.9030
343 QUZ 0.9029
344 MXN 0.9028
345 8WO 0.9027
346 PRY 0.9026
347 CRS 0.9026
348 8CL 0.9026
349 NPY 0.9020
350 FBS 0.9020
351 C2A 0.9019
352 QY9 0.9018
353 IPH 0.9017
354 MUC 0.9016
355 ZBT 0.9015
356 ES6 0.9015
357 HT4 0.9014
358 0HN 0.9013
359 0HO 0.9011
360 ABI 0.9007
361 IFL 0.9005
362 B53 0.9005
363 MS9 0.9005
364 JB5 0.9004
365 1SA 0.9004
366 BVG 0.9002
367 1DU 0.9001
368 7N0 0.9000
369 BGC 0.9000
370 LZM 0.8999
371 QXW 0.8999
372 GAB 0.8999
373 268 0.8997
374 PAC 0.8997
375 GJZ 0.8996
376 PRO 0.8995
377 G4D 0.8993
378 IND 0.8992
379 42A 0.8992
380 IFM 0.8991
381 CWJ 0.8990
382 FB2 0.8988
383 FUL 0.8987
384 HAI 0.8987
385 4SV 0.8986
386 R1X 0.8986
387 DYA 0.8985
388 FEH 0.8985
389 HCS 0.8985
390 GCS 0.8985
391 GIF 0.8984
392 JKE 0.8984
393 1DW 0.8982
394 FCR 0.8981
395 SHA 0.8981
396 5NI 0.8980
397 PCA 0.8980
398 MBN 0.8979
399 BZI 0.8979
400 HHQ 0.8971
401 IF7 0.8971
402 6NI 0.8970
403 3NY 0.8970
404 RSF 0.8969
405 2CK 0.8969
406 LZ1 0.8969
407 93B 0.8967
408 TLA 0.8967
409 GOJ 0.8966
410 PRA 0.8966
411 6M9 0.8965
412 53C 0.8963
413 BZF 0.8963
414 ES7 0.8962
415 0R1 0.8961
416 G2F 0.8961
417 CYH 0.8961
418 94W 0.8960
419 RIP 0.8960
420 G3F 0.8957
421 67N 0.8957
422 5WV 0.8957
423 449 0.8956
424 J1Z 0.8955
425 AGK 0.8955
426 4AA 0.8953
427 ASP 0.8952
428 GVH 0.8951
429 JB8 0.8950
430 OVV 0.8950
431 264 0.8950
432 JDN 0.8948
433 2IM 0.8948
434 RM1 0.8946
435 ISN 0.8945
436 NOY 0.8944
437 KKN 0.8943
438 3HB 0.8943
439 GLA 0.8943
440 URS 0.8943
441 XYS 0.8942
442 OXZ 0.8941
443 4JP 0.8941
444 TP5 0.8940
445 PMB 0.8940
446 TZC 0.8940
447 COI 0.8940
448 L99 0.8939
449 IP0 0.8938
450 IV2 0.8938
451 2HQ 0.8936
452 SR1 0.8935
453 TMT 0.8934
454 FUC 0.8934
455 3OC 0.8933
456 FOA 0.8933
457 7WV 0.8933
458 7HQ 0.8933
459 SW7 0.8931
460 0CT 0.8930
461 F05 0.8930
462 MZ0 0.8929
463 MPI 0.8929
464 DMD 0.8928
465 HEW 0.8928
466 RB5 0.8927
467 T6C 0.8926
468 JBN 0.8926
469 6M4 0.8926
470 3AB 0.8925
471 GDE 0.8925
472 I3E 0.8924
473 4CS 0.8921
474 AZF 0.8921
475 4SD 0.8920
476 DBH 0.8919
477 SRT 0.8918
478 B3R 0.8918
479 2HU 0.8916
480 MNM 0.8916
481 9YL 0.8915
482 0RW 0.8913
483 P2D 0.8910
484 TIU 0.8910
485 7W4 0.8910
486 TZL 0.8909
487 3HA 0.8907
488 2PC 0.8907
489 HYP 0.8907
490 1WD 0.8906
491 C21 0.8906
492 WOT 0.8905
493 4NB 0.8905
494 2KT 0.8905
495 FBJ 0.8903
496 8S0 0.8903
497 OGA 0.8902
498 PYC 0.8902
499 CEJ 0.8902
500 GAG 0.8902
501 OKG 0.8901
502 ROR 0.8901
503 3V4 0.8900
504 A2Q 0.8898
505 M1A 0.8897
506 4AP 0.8897
507 F4E 0.8896
508 GYE 0.8896
509 6X8 0.8895
510 ZXD 0.8894
511 ECE 0.8894
512 SKM 0.8894
513 49F 0.8894
514 60P 0.8893
515 6NA 0.8891
516 86J 0.8890
517 5LA 0.8889
518 UY7 0.8887
519 273 0.8887
520 DHK 0.8886
521 JBE 0.8884
522 SNO 0.8882
523 KJU 0.8881
524 IMR 0.8881
525 1P7 0.8880
526 LYL 0.8880
527 AKG 0.8879
528 SIN 0.8877
529 5AC 0.8876
530 HIO 0.8874
531 M3T 0.8873
532 265 0.8872
533 278 0.8871
534 DHS 0.8868
535 X6X 0.8868
536 QBK 0.8867
537 4XS 0.8867
538 284 0.8867
539 BZ2 0.8866
540 149 0.8866
541 3NT 0.8865
542 5B1 0.8865
543 K34 0.8864
544 8ZE 0.8863
545 2AP 0.8861
546 HVK 0.8861
547 QSH 0.8861
548 2H5 0.8859
549 3ID 0.8859
550 3AP 0.8858
551 ASN 0.8858
552 NLE 0.8857
553 0CU 0.8857
554 YH7 0.8856
555 CWM 0.8855
556 DHY 0.8854
557 JZ9 0.8853
558 WCE 0.8853
559 XAN 0.8853
560 GXL 0.8852
561 5QX 0.8848
562 3DO 0.8846
563 BCP 0.8846
564 Q88 0.8844
565 0MK 0.8844
566 J9N 0.8844
567 MLA 0.8844
568 SOE 0.8844
569 KDV 0.8843
570 EHM 0.8843
571 3M0 0.8841
572 DMG 0.8840
573 KIV 0.8840
574 6RQ 0.8839
575 12Q 0.8838
576 DE5 0.8838
577 7MH 0.8836
578 GBD 0.8836
579 MAK 0.8835
580 ICB 0.8834
581 B57 0.8834
582 N2I 0.8834
583 TTL 0.8831
584 8WT 0.8831
585 M6W 0.8831
586 XYL 0.8831
587 MQN 0.8830
588 DFU 0.8830
589 3CH 0.8829
590 7W1 0.8828
591 TBP 0.8828
592 4YO 0.8827
593 4H2 0.8826
594 1XM 0.8826
595 PYG 0.8826
596 LCN 0.8826
597 RCO 0.8825
598 M4S 0.8824
599 LGA 0.8824
600 4XV 0.8822
601 5HN 0.8821
602 40E 0.8821
603 35C 0.8820
604 JAB 0.8820
605 0JD 0.8820
606 4JT 0.8820
607 CSS 0.8820
608 2CH 0.8819
609 3CE 0.8819
610 GIV 0.8819
611 LEU 0.8819
612 4FH 0.8819
613 HH5 0.8817
614 SEP 0.8817
615 4SX 0.8817
616 LQ2 0.8817
617 EKZ 0.8815
618 EUG 0.8814
619 URC 0.8814
620 BEW 0.8814
621 KJH 0.8814
622 6FZ 0.8813
623 2BX 0.8812
624 AL0 0.8811
625 XQG 0.8811
626 HRZ 0.8811
627 LNR 0.8810
628 URP 0.8809
629 5GU 0.8809
630 FGZ 0.8809
631 DIE 0.8809
632 2D0 0.8808
633 4HM 0.8808
634 280 0.8808
635 9EW 0.8805
636 MLI 0.8804
637 3PY 0.8804
638 BOA 0.8803
639 938 0.8802
640 OXQ 0.8801
641 GAF 0.8801
642 GZL 0.8801
643 ICC 0.8800
644 X0V 0.8799
645 RBL 0.8798
646 V55 0.8798
647 H3M 0.8798
648 9PO 0.8797
649 V1L 0.8797
650 DSN 0.8796
651 BVF 0.8796
652 3F0 0.8795
653 XAZ 0.8795
654 4JC 0.8795
655 HPY 0.8795
656 BTY 0.8793
657 SGL 0.8793
658 0TU 0.8792
659 4JQ 0.8791
660 CTL 0.8790
661 VAL 0.8790
662 8TX 0.8789
663 E60 0.8789
664 HIU 0.8788
665 URA 0.8788
666 RNO 0.8788
667 GUN 0.8786
668 M1Q 0.8785
669 L60 0.8784
670 OVM 0.8782
671 NMJ 0.8782
672 TSS 0.8782
673 7B4 0.8780
674 QBM 0.8778
675 3MB 0.8777
676 173 0.8777
677 47J 0.8776
678 GXY 0.8776
679 4Z4 0.8775
680 JFD 0.8775
681 ES0 0.8774
682 A7N 0.8774
683 JBK 0.8772
684 ABU 0.8772
685 HQT 0.8771
686 BRT 0.8770
687 SYV 0.8770
688 9DG 0.8769
689 G3P 0.8769
690 MBG 0.8768
691 HTS 0.8767
692 5JQ 0.8766
693 2FG 0.8762
694 MED 0.8762
695 B55 0.8760
696 6AP 0.8760
697 FDK 0.8759
698 2XX 0.8758
699 NVA 0.8757
700 RHU 0.8757
701 7MU 0.8754
702 CIG 0.8754
703 E7Z 0.8753
704 26D 0.8753
705 J9T 0.8753
706 KG7 0.8750
707 150 0.8750
708 LEA 0.8750
709 13P 0.8750
710 GTQ 0.8749
711 2CM 0.8747
712 CWS 0.8746
713 ESX 0.8746
714 J6W 0.8745
715 HSO 0.8743
716 TFB 0.8742
717 HYN 0.8741
718 LG3 0.8741
719 SVN 0.8740
720 ABE 0.8740
721 45C 0.8740
722 2FT 0.8740
723 KBZ 0.8739
724 F0J 0.8739
725 HX2 0.8738
726 8GC 0.8737
727 5QY 0.8737
728 PEP 0.8735
729 ILE 0.8734
730 3BZ 0.8733
731 DCY 0.8732
732 HPA 0.8731
733 1GN 0.8731
734 7CZ 0.8730
735 JIF 0.8730
736 5JL 0.8730
737 2HG 0.8729
738 ZZ3 0.8728
739 XIX 0.8727
740 2CO 0.8726
741 FBV 0.8726
742 3MC 0.8721
743 ICO 0.8721
744 6M1 0.8720
745 LG5 0.8718
746 A65 0.8717
747 75K 0.8715
748 3PF 0.8715
749 A2F 0.8713
750 R8V 0.8712
751 94N 0.8711
752 SX1 0.8711
753 SWD 0.8710
754 BCU 0.8708
755 FB1 0.8708
756 HY3 0.8708
757 2CQ 0.8707
758 D48 0.8707
759 1DV 0.8706
760 54G 0.8706
761 DUB 0.8706
762 6MH 0.8705
763 MBD 0.8704
764 EA1 0.8703
765 FUB 0.8702
766 CYT 0.8700
767 TC7 0.8700
768 2RH 0.8700
769 F4Z 0.8700
770 HHA 0.8699
771 IFP 0.8693
772 CAQ 0.8693
773 6F0 0.8692
774 GRE 0.8691
775 6GU 0.8690
776 FCA 0.8690
777 ABA 0.8690
778 A7W 0.8689
779 HLR 0.8688
780 24T 0.8687
781 MSR 0.8686
782 CN0 0.8685
783 OW4 0.8685
784 MRW 0.8684
785 MAN 0.8684
786 VNL 0.8682
787 F31 0.8682
788 SKA 0.8680
789 RUU 0.8679
790 1SQ 0.8678
791 8LG 0.8678
792 DIN 0.8677
793 5RN 0.8677
794 KUF 0.8676
795 PRS 0.8675
796 8GF 0.8675
797 AZA 0.8674
798 1AN 0.8673
799 93Q 0.8671
800 0P6 0.8671
801 M1E 0.8670
802 DX4 0.8670
803 GMN 0.8667
804 1LQ 0.8667
805 2MY 0.8664
806 A5E 0.8663
807 FUD 0.8663
808 G3E 0.8662
809 6KT 0.8661
810 THE 0.8661
811 DMJ 0.8661
812 R67 0.8660
813 JLZ 0.8657
814 1WG 0.8656
815 FP2 0.8655
816 H76 0.8654
817 2C9 0.8654
818 XLS 0.8654
819 SE2 0.8653
820 QX2 0.8652
821 FDB 0.8651
822 3MH 0.8651
823 ADE 0.8651
824 TGX 0.8650
825 0TR 0.8650
826 4M4 0.8650
827 L14 0.8649
828 J5I 0.8648
829 JBH 0.8647
830 TM4 0.8647
831 4HC 0.8647
832 WOO 0.8646
833 ES1 0.8646
834 FUF 0.8644
835 5M0 0.8642
836 OVP 0.8642
837 NFM 0.8641
838 G3H 0.8641
839 S24 0.8640
840 AZG 0.8640
841 069 0.8640
842 Q24 0.8639
843 MRZ 0.8639
844 ALO 0.8638
845 JZ0 0.8638
846 OXE 0.8637
847 J9W 0.8635
848 JPZ 0.8635
849 EV0 0.8634
850 8IG 0.8634
851 FH2 0.8634
852 MEW 0.8633
853 HQY 0.8633
854 5IQ 0.8633
855 1LM 0.8631
856 1NP 0.8631
857 AJ2 0.8631
858 3FA 0.8630
859 5SG 0.8629
860 FK8 0.8628
861 141 0.8628
862 4YS 0.8627
863 5Q0 0.8626
864 AAE 0.8626
865 QWW 0.8624
866 O72 0.8623
867 BTE 0.8622
868 10L 0.8620
869 5RG 0.8619
870 4VY 0.8618
871 MO8 0.8617
872 SNU 0.8614
873 9R5 0.8612
874 FUM 0.8610
875 FFP 0.8609
876 KJY 0.8608
877 DRL 0.8608
878 12T 0.8607
879 FLM 0.8607
880 3Z7 0.8607
881 M2H 0.8606
882 M5K 0.8606
883 PXL 0.8605
884 4ZC 0.8600
885 NDH 0.8595
886 2ZV 0.8591
887 92Z 0.8589
888 ES4 0.8587
889 290 0.8586
890 S2G 0.8586
891 KYD 0.8584
892 TZF 0.8584
893 RNT 0.8583
894 N5J 0.8583
895 L89 0.8583
896 C5J 0.8580
897 MSE 0.8580
898 IGA 0.8580
899 CFP 0.8580
900 AQO 0.8579
901 PQ0 0.8578
902 HPS 0.8573
903 1XX 0.8573
904 AS3 0.8573
905 2A7 0.8568
906 24W 0.8567
907 PRI 0.8565
908 YAN 0.8565
909 DEE 0.8565
910 5RO 0.8564
911 76X 0.8564
912 UNJ 0.8561
913 2AF 0.8560
914 9HX 0.8559
915 B85 0.8555
916 Z6J 0.8549
917 4XH 0.8546
918 PE0 0.8540
919 7HP 0.8540
920 PRF 0.8533
921 1CO 0.8531
922 8K2 0.8530
923 4BY 0.8520
924 AZ8 0.8517
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4YRI; Ligand: 4JH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4yri.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 4YRI; Ligand: 4JH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4yri.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback