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Receptor
PDB id Resolution Class Description Source Keywords
4Z2S 1.7 Å NON-ENZYME: BINDING THE CRYSTAL STRUCTURE OF SCLEROTIUM ROLFSII LECTIN VARIANT 2 COMPLEX WITH N-ACETYL-GLUCOSAMINE ATHELIA ROLFSII LECTIN SUGAR BINDING PROTEIN CARBOHYDRATE- BINDING SPECIFISUGAR BINDING PROTEIN
Ref.: MOLECULAR CLONING, CARBOHYDRATE SPECIFICITY AND THE STRUCTURE OF TWO SCLEROTIUM ROLFSII LECTIN VARIANTS MOLECULES V. 20 10848 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NAG B:203;
A:203;
Valid;
Valid;
none;
none;
submit data
221.208 C8 H15 N O6 CC(=O...
NDG A:202;
B:202;
Valid;
Valid;
none;
none;
submit data
221.208 C8 H15 N O6 CC(=O...
TRS A:201;
Invalid;
none;
submit data
122.143 C4 H12 N O3 C(C(C...
MPD B:201;
Invalid;
none;
submit data
118.174 C6 H14 O2 C[C@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4Z2S 1.7 Å NON-ENZYME: BINDING THE CRYSTAL STRUCTURE OF SCLEROTIUM ROLFSII LECTIN VARIANT 2 COMPLEX WITH N-ACETYL-GLUCOSAMINE ATHELIA ROLFSII LECTIN SUGAR BINDING PROTEIN CARBOHYDRATE- BINDING SPECIFISUGAR BINDING PROTEIN
Ref.: MOLECULAR CLONING, CARBOHYDRATE SPECIFICITY AND THE STRUCTURE OF TWO SCLEROTIUM ROLFSII LECTIN VARIANTS MOLECULES V. 20 10848 2015
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 4Z2Q - NDG C8 H15 N O6 CC(=O)N[C@....
2 4Z2S - NDG C8 H15 N O6 CC(=O)N[C@....
70% Homology Family (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 391 families.
1 1Y2U - NAG GAL n/a n/a
2 1Y2X - NGA SER GAL n/a n/a
3 1Y2W - NAG C8 H15 N O6 CC(=O)N[C@....
4 1Y2V - NGA GAL SER n/a n/a
5 4Z2Q - NDG C8 H15 N O6 CC(=O)N[C@....
6 4Z2S - NDG C8 H15 N O6 CC(=O)N[C@....
50% Homology Family (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 298 families.
1 1Y2U - NAG GAL n/a n/a
2 1Y2X - NGA SER GAL n/a n/a
3 1Y2W - NAG C8 H15 N O6 CC(=O)N[C@....
4 1Y2V - NGA GAL SER n/a n/a
5 4Z2Q - NDG C8 H15 N O6 CC(=O)N[C@....
6 4Z2S - NDG C8 H15 N O6 CC(=O)N[C@....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: NAG; Similar ligands found: 105
No: Ligand ECFP6 Tc MDL keys Tc
1 NGA 1 1
2 NAG 1 1
3 A2G 1 1
4 BM3 1 1
5 HSQ 1 1
6 NDG 1 1
7 BGN 0.638298 0.888889
8 SIZ 0.630435 0.906977
9 YX1 0.625 0.65
10 STZ 0.612245 0.65
11 4QY 0.591837 0.735849
12 BMX 0.591837 0.735849
13 16G 0.591837 0.735849
14 9C1 0.58 0.886364
15 SNG 0.5625 0.866667
16 NGS 0.54902 0.661017
17 NDG NAG 0.54386 0.833333
18 CBS 0.54386 0.833333
19 NAG GDL 0.54386 0.833333
20 CBS CBS 0.54386 0.833333
21 ASG 0.538462 0.661017
22 BG8 0.537037 0.906977
23 MAG 0.530612 0.909091
24 2F8 0.530612 0.909091
25 NDG GAL 0.517857 0.888889
26 NLC 0.517857 0.888889
27 GAL NDG 0.517857 0.888889
28 NAG A2G 0.517241 0.833333
29 4V5 0.517241 0.829787
30 NAG NGA 0.517241 0.833333
31 4UZ 0.508475 0.808511
32 NAG NAG NAG NAG NDG 0.508197 0.816327
33 NDG NAG NAG NAG 0.508197 0.816327
34 NAG NAG NDG 0.508197 0.816327
35 NAG NAG NDG NAG 0.508197 0.816327
36 CTO 0.508197 0.816327
37 NDG NAG NAG NDG 0.508197 0.816327
38 NAG NAG NAG NDG 0.508197 0.816327
39 NDG NAG NAG 0.508197 0.816327
40 NAG NAG NAG NAG NAG 0.508197 0.816327
41 NAG NAG NAG NAG NAG NAG 0.508197 0.816327
42 NAG NAG NAG NAG NAG NAG NAG NAG 0.508197 0.816327
43 MQG 0.5 0.698113
44 NBG 0.5 0.951219
45 GAL NGA 0.491228 0.888889
46 A2G GAL 0.491228 0.888889
47 GAL A2G 0.491228 0.888889
48 AMU 0.490909 0.930233
49 NG1 0.490566 0.754717
50 GN1 0.490566 0.754717
51 NAG GAL 0.474576 0.888889
52 GAL NAG 0.474576 0.888889
53 NAG FUC 0.474576 0.866667
54 NAG GAL NAG 0.455882 0.833333
55 3YW 0.448276 0.930233
56 GLA GAL NAG 0.446154 0.888889
57 MAN BMA NAG 0.446154 0.888889
58 NGA GAL 0.428571 0.869565
59 FUC GAL NAG 0.426471 0.869565
60 GAL NAG FUC 0.426471 0.869565
61 DR2 0.426471 0.869565
62 NAG GAL FUC 0.426471 0.869565
63 NDG GAL FUC 0.426471 0.869565
64 FUC GAL NDG 0.426471 0.869565
65 FUL GAL NAG 0.426471 0.869565
66 G6S NAG 0.426471 0.645161
67 TNR 0.42623 0.833333
68 GYU 0.42623 0.740741
69 GAL NGA A2G 0.424242 0.833333
70 NAG BDP 0.421875 0.851064
71 NAG MBG 0.419355 0.851064
72 NGA GAL BGC 0.41791 0.888889
73 NAG NDG 0.415385 0.784314
74 NAG NAG 0.415385 0.784314
75 AZC 0.415094 0.795918
76 SN5 SN5 0.412698 0.705882
77 A2G MBG 0.412698 0.851064
78 MBG A2G 0.412698 0.851064
79 HS2 0.411765 0.8125
80 5AX 0.411765 0.866667
81 NAG MAN BMA 0.411765 0.888889
82 6ZC 0.409091 0.655738
83 LEC 0.409091 0.655738
84 TCG 0.408451 0.689655
85 GAL BGC NAG GAL 0.408451 0.888889
86 NAG MAN 0.40625 0.851064
87 WOO 0.404762 0.7
88 MAN 0.404762 0.7
89 GAL 0.404762 0.7
90 BGC 0.404762 0.7
91 BMA 0.404762 0.7
92 GLA 0.404762 0.7
93 ALL 0.404762 0.7
94 GLC 0.404762 0.7
95 GXL 0.404762 0.7
96 GIV 0.404762 0.7
97 NAG AMU 0.402778 0.8
98 NAG MUB 0.402778 0.8
99 NAG A2G GAL 0.402778 0.833333
100 A2G GAL FUC 0.4 0.869565
101 FUC GLA A2G 0.4 0.869565
102 DR3 0.4 0.869565
103 A2G GLA FUC 0.4 0.869565
104 NGA GAL FUC 0.4 0.869565
105 FUC GAL A2G 0.4 0.869565
Ligand no: 2; Ligand: NDG; Similar ligands found: 105
No: Ligand ECFP6 Tc MDL keys Tc
1 NGA 1 1
2 NAG 1 1
3 A2G 1 1
4 BM3 1 1
5 HSQ 1 1
6 NDG 1 1
7 BGN 0.638298 0.888889
8 SIZ 0.630435 0.906977
9 YX1 0.625 0.65
10 STZ 0.612245 0.65
11 4QY 0.591837 0.735849
12 BMX 0.591837 0.735849
13 16G 0.591837 0.735849
14 9C1 0.58 0.886364
15 SNG 0.5625 0.866667
16 NGS 0.54902 0.661017
17 NDG NAG 0.54386 0.833333
18 CBS 0.54386 0.833333
19 NAG GDL 0.54386 0.833333
20 CBS CBS 0.54386 0.833333
21 ASG 0.538462 0.661017
22 BG8 0.537037 0.906977
23 MAG 0.530612 0.909091
24 2F8 0.530612 0.909091
25 NDG GAL 0.517857 0.888889
26 NLC 0.517857 0.888889
27 GAL NDG 0.517857 0.888889
28 NAG A2G 0.517241 0.833333
29 4V5 0.517241 0.829787
30 NAG NGA 0.517241 0.833333
31 4UZ 0.508475 0.808511
32 NAG NAG NAG NAG NDG 0.508197 0.816327
33 NDG NAG NAG NAG 0.508197 0.816327
34 NAG NAG NDG 0.508197 0.816327
35 NAG NAG NDG NAG 0.508197 0.816327
36 CTO 0.508197 0.816327
37 NDG NAG NAG NDG 0.508197 0.816327
38 NAG NAG NAG NDG 0.508197 0.816327
39 NDG NAG NAG 0.508197 0.816327
40 NAG NAG NAG NAG NAG 0.508197 0.816327
41 NAG NAG NAG NAG NAG NAG 0.508197 0.816327
42 NAG NAG NAG NAG NAG NAG NAG NAG 0.508197 0.816327
43 MQG 0.5 0.698113
44 NBG 0.5 0.951219
45 GAL NGA 0.491228 0.888889
46 A2G GAL 0.491228 0.888889
47 GAL A2G 0.491228 0.888889
48 AMU 0.490909 0.930233
49 NG1 0.490566 0.754717
50 GN1 0.490566 0.754717
51 NAG GAL 0.474576 0.888889
52 GAL NAG 0.474576 0.888889
53 NAG FUC 0.474576 0.866667
54 NAG GAL NAG 0.455882 0.833333
55 3YW 0.448276 0.930233
56 GLA GAL NAG 0.446154 0.888889
57 MAN BMA NAG 0.446154 0.888889
58 NGA GAL 0.428571 0.869565
59 FUC GAL NAG 0.426471 0.869565
60 GAL NAG FUC 0.426471 0.869565
61 DR2 0.426471 0.869565
62 NAG GAL FUC 0.426471 0.869565
63 NDG GAL FUC 0.426471 0.869565
64 FUC GAL NDG 0.426471 0.869565
65 FUL GAL NAG 0.426471 0.869565
66 G6S NAG 0.426471 0.645161
67 TNR 0.42623 0.833333
68 GYU 0.42623 0.740741
69 GAL NGA A2G 0.424242 0.833333
70 NAG BDP 0.421875 0.851064
71 NAG MBG 0.419355 0.851064
72 NGA GAL BGC 0.41791 0.888889
73 NAG NDG 0.415385 0.784314
74 NAG NAG 0.415385 0.784314
75 AZC 0.415094 0.795918
76 SN5 SN5 0.412698 0.705882
77 A2G MBG 0.412698 0.851064
78 MBG A2G 0.412698 0.851064
79 HS2 0.411765 0.8125
80 5AX 0.411765 0.866667
81 NAG MAN BMA 0.411765 0.888889
82 6ZC 0.409091 0.655738
83 LEC 0.409091 0.655738
84 TCG 0.408451 0.689655
85 GAL BGC NAG GAL 0.408451 0.888889
86 NAG MAN 0.40625 0.851064
87 WOO 0.404762 0.7
88 MAN 0.404762 0.7
89 GAL 0.404762 0.7
90 BGC 0.404762 0.7
91 BMA 0.404762 0.7
92 GLA 0.404762 0.7
93 ALL 0.404762 0.7
94 GLC 0.404762 0.7
95 GXL 0.404762 0.7
96 GIV 0.404762 0.7
97 NAG AMU 0.402778 0.8
98 NAG MUB 0.402778 0.8
99 NAG A2G GAL 0.402778 0.833333
100 A2G GAL FUC 0.4 0.869565
101 FUC GLA A2G 0.4 0.869565
102 DR3 0.4 0.869565
103 A2G GLA FUC 0.4 0.869565
104 NGA GAL FUC 0.4 0.869565
105 FUC GAL A2G 0.4 0.869565
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4Z2S; Ligand: NAG; Similar sites found with APoc: 100
This union binding pocket(no: 1) in the query (biounit: 4z2s.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 4G6I RS3 None
2 5AHM IMP None
3 1FK5 OLA None
4 1GAR U89 None
5 4AVB ACO None
6 2P4T NAP None
7 5OVC ACE GLU ALA GLN THR ARG LEU None
8 4HMX FMN 0.704225
9 4HMX WUB 0.704225
10 2QX0 APC 1.40845
11 2C43 COA 2.11268
12 1YKI FMN 2.11268
13 1YKI NFZ 2.11268
14 1KQB BEZ 2.11268
15 1KQB FMN 2.11268
16 1ICV FMN 2.11268
17 1TMM APC 3.52113
18 1TMM HHR 3.52113
19 3G6K FAD 3.52113
20 3G6K POP 3.52113
21 5DWQ SFG 3.52113
22 2Q1W NAD 3.52113
23 1TLL NAP 3.52113
24 3WR7 COA 3.52113
25 3GDN MXN 3.52113
26 5DXA SFG 3.52113
27 5DX1 SFG 3.52113
28 2O3Z AI7 3.52113
29 1KYZ SAH 3.52113
30 5DX0 SFG 3.52113
31 5DX8 SFG 3.52113
32 5VN0 NAI 3.52113
33 1L6O SER LEU LYS LEU MET THR THR VAL 4.21053
34 2XMY CDK 4.22535
35 3AB1 FAD 4.22535
36 2CDU FAD 4.22535
37 2C91 NAP 4.22535
38 1SVM ATP 4.22535
39 2HS3 FGR 4.22535
40 4NRT 2NG 4.22535
41 4OOP DUP 4.22535
42 3NB0 G6P 4.22535
43 1YVD GNP 4.22535
44 5WHT SIA GAL GLC 4.34783
45 6DWD HDV 4.92958
46 6DWD GTP 4.92958
47 4DS0 A2G GAL NAG FUC 4.92958
48 5ETR APC 4.92958
49 5ETR 5RW 4.92958
50 1PVN MZP 5.05319
51 2A9D MTE 5.6338
52 4NTD FAD 5.6338
53 6BN0 NAG NAG NAG NAG NAG NAG 6.32911
54 4U03 TLL 6.33803
55 4U03 GTP 6.33803
56 3NRZ FAD 6.33803
57 4R57 ACO 6.33803
58 1RC0 KT5 6.33803
59 1FIQ FAD 7.04225
60 2I6A 5I5 7.04225
61 6C6O ENG 7.04225
62 2ZW5 COA 7.04225
63 4TR9 38D 7.04225
64 4AG8 AXI 7.04225
65 3DZ6 M8E 7.74648
66 4LO6 SIA GAL 7.74648
67 2C6Q NDP 8.4507
68 3VDB 149 8.4507
69 1PVC ILE SER GLU VAL 8.4507
70 5AE2 FAD 8.4507
71 1ERB ETR 8.4507
72 4Z87 5GP 8.4507
73 4HMT FMN 8.4507
74 4HMT NNV 8.4507
75 1T9M FMN 8.4507
76 4MRT COA 9.85915
77 1QR0 COA 9.85915
78 3CZ7 ACO 9.85915
79 4LX0 BEF GDP 10.5634
80 5OGX FAD 10.5634
81 5XFV FMN 10.5634
82 5JAQ NAI 10.5634
83 1TKE SER 10.5634
84 5V59 8X1 10.5634
85 5JFL NAD 11.2676
86 1XTT U5P 11.2676
87 2VUT NAD 11.9718
88 1ZFJ IMP 11.9718
89 2ZBA COA 11.9718
90 1OVD FMN 13.3803
91 1OVD ORO 13.3803
92 5WA0 MSS 14.0845
93 4PW9 MSS 14.0845
94 5JCZ GDP 15.493
95 2ZAT NAP 16.1972
96 4CZG QH3 16.9014
97 2YVJ NAI 17.4312
98 2HV8 GTP 21.875
99 4PYW ACE THR THR ALA ILE NH2 23.9437
100 6BMN PAP 30.2817
Pocket No.: 2; Query (leader) PDB : 4Z2S; Ligand: NDG; Similar sites found with APoc: 100
This union binding pocket(no: 2) in the query (biounit: 4z2s.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 4G6I RS3 None
2 5AHM IMP None
3 1FK5 OLA None
4 1GAR U89 None
5 4AVB ACO None
6 2P4T NAP None
7 5OVC ACE GLU ALA GLN THR ARG LEU None
8 4HMX FMN 0.704225
9 4HMX WUB 0.704225
10 2QX0 APC 1.40845
11 2C43 COA 2.11268
12 1YKI FMN 2.11268
13 1YKI NFZ 2.11268
14 1KQB BEZ 2.11268
15 1KQB FMN 2.11268
16 1ICV FMN 2.11268
17 1TMM APC 3.52113
18 1TMM HHR 3.52113
19 3G6K FAD 3.52113
20 3G6K POP 3.52113
21 5DWQ SFG 3.52113
22 2Q1W NAD 3.52113
23 1TLL NAP 3.52113
24 3WR7 COA 3.52113
25 3GDN MXN 3.52113
26 5DXA SFG 3.52113
27 5DX1 SFG 3.52113
28 2O3Z AI7 3.52113
29 1KYZ SAH 3.52113
30 5DX0 SFG 3.52113
31 5DX8 SFG 3.52113
32 5VN0 NAI 3.52113
33 1L6O SER LEU LYS LEU MET THR THR VAL 4.21053
34 2XMY CDK 4.22535
35 3AB1 FAD 4.22535
36 2CDU FAD 4.22535
37 2C91 NAP 4.22535
38 1SVM ATP 4.22535
39 2HS3 FGR 4.22535
40 4NRT 2NG 4.22535
41 4OOP DUP 4.22535
42 3NB0 G6P 4.22535
43 1YVD GNP 4.22535
44 5WHT SIA GAL GLC 4.34783
45 6DWD HDV 4.92958
46 6DWD GTP 4.92958
47 4DS0 A2G GAL NAG FUC 4.92958
48 5ETR APC 4.92958
49 5ETR 5RW 4.92958
50 1PVN MZP 5.05319
51 2A9D MTE 5.6338
52 4NTD FAD 5.6338
53 6BN0 NAG NAG NAG NAG NAG NAG 6.32911
54 4U03 TLL 6.33803
55 4U03 GTP 6.33803
56 3NRZ FAD 6.33803
57 4R57 ACO 6.33803
58 1RC0 KT5 6.33803
59 1FIQ FAD 7.04225
60 2I6A 5I5 7.04225
61 6C6O ENG 7.04225
62 2ZW5 COA 7.04225
63 4TR9 38D 7.04225
64 4AG8 AXI 7.04225
65 3DZ6 M8E 7.74648
66 4LO6 SIA GAL 7.74648
67 2C6Q NDP 8.4507
68 3VDB 149 8.4507
69 1PVC ILE SER GLU VAL 8.4507
70 5AE2 FAD 8.4507
71 1ERB ETR 8.4507
72 4Z87 5GP 8.4507
73 4HMT FMN 8.4507
74 4HMT NNV 8.4507
75 1T9M FMN 8.4507
76 4MRT COA 9.85915
77 1QR0 COA 9.85915
78 3CZ7 ACO 9.85915
79 4LX0 BEF GDP 10.5634
80 5OGX FAD 10.5634
81 5XFV FMN 10.5634
82 5JAQ NAI 10.5634
83 1TKE SER 10.5634
84 5V59 8X1 10.5634
85 5JFL NAD 11.2676
86 1XTT U5P 11.2676
87 2VUT NAD 11.9718
88 1ZFJ IMP 11.9718
89 2ZBA COA 11.9718
90 1OVD FMN 13.3803
91 1OVD ORO 13.3803
92 5WA0 MSS 14.0845
93 4PW9 MSS 14.0845
94 5JCZ GDP 15.493
95 2ZAT NAP 16.1972
96 4CZG QH3 16.9014
97 2YVJ NAI 17.4312
98 2HV8 GTP 21.875
99 4PYW ACE THR THR ALA ILE NH2 23.9437
100 6BMN PAP 30.2817
Pocket No.: 3; Query (leader) PDB : 4Z2S; Ligand: NDG; Similar sites found with APoc: 39
This union binding pocket(no: 3) in the query (biounit: 4z2s.bio2) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 2HMT NAI None
2 6AIX A3P 1.40845
3 5J5R IMP 2.11268
4 5J5R 6G1 2.11268
5 6GNC FAD 2.11268
6 3A06 NDP 2.8169
7 3OTI C0T 2.8169
8 3V91 UPG 2.8169
9 2BP1 NDP 4.22535
10 4IXH IMP 4.22535
11 2D7C GTP 4.22535
12 4AF0 IMP 4.22535
13 2ZFN ACO 4.22535
14 4O4K 2PK 4.92958
15 5VC5 96M 4.92958
16 2FT0 ACO 4.92958
17 5D9J 0N8 5.6338
18 1QD1 FON 6.33803
19 4U9U FAD 6.33803
20 4QVB F42 7.04225
21 2BPM 529 7.04225
22 5IVE 6E8 7.04225
23 3P48 DUP 7.04225
24 4Z0G 5GP 8.4507
25 2C6Q IMP 8.4507
26 6EBQ FMN 9.15493
27 3ORQ ADP 9.15493
28 6GL8 F3Q 9.88372
29 4KVG GTP 10.5634
30 1SOX MTE 12.6761
31 5LEF GTP 12.6761
32 1ZC3 GNP 13.3803
33 1Z0J GTP 15.2542
34 5NII FAD 15.493
35 1I1D COA 17.6056
36 1I1D 16G 17.6056
37 2Y8E GNP 18.3099
38 5IH9 6BF 19.0141
39 3R5J ACE ALA ASP VAL ALA ASA 19.6429
Pocket No.: 4; Query (leader) PDB : 4Z2S; Ligand: NAG; Similar sites found with APoc: 39
This union binding pocket(no: 4) in the query (biounit: 4z2s.bio2) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 2HMT NAI None
2 6AIX A3P 1.40845
3 5J5R IMP 2.11268
4 5J5R 6G1 2.11268
5 6GNC FAD 2.11268
6 3A06 NDP 2.8169
7 3OTI C0T 2.8169
8 3V91 UPG 2.8169
9 2BP1 NDP 4.22535
10 4IXH IMP 4.22535
11 2D7C GTP 4.22535
12 4AF0 IMP 4.22535
13 2ZFN ACO 4.22535
14 4O4K 2PK 4.92958
15 5VC5 96M 4.92958
16 2FT0 ACO 4.92958
17 5D9J 0N8 5.6338
18 1QD1 FON 6.33803
19 4U9U FAD 6.33803
20 4QVB F42 7.04225
21 2BPM 529 7.04225
22 5IVE 6E8 7.04225
23 3P48 DUP 7.04225
24 4Z0G 5GP 8.4507
25 2C6Q IMP 8.4507
26 6EBQ FMN 9.15493
27 3ORQ ADP 9.15493
28 6GL8 F3Q 9.88372
29 4KVG GTP 10.5634
30 1SOX MTE 12.6761
31 5LEF GTP 12.6761
32 1ZC3 GNP 13.3803
33 1Z0J GTP 15.2542
34 5NII FAD 15.493
35 1I1D COA 17.6056
36 1I1D 16G 17.6056
37 2Y8E GNP 18.3099
38 5IH9 6BF 19.0141
39 3R5J ACE ALA ASP VAL ALA ASA 19.6429
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