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Receptor
PDB id Resolution Class Description Source Keywords
4ZGS 2.46 Å EC: 1.-.-.- IDENTIFICATION OF THE PYRUVATE REDUCTASE OF CHLAMYDOMONAS RE CHLAMYDOMONAS REINHARDTII PYRUVATE DEHYDROGENASE FERMENTATION GREEN ALGA BIOHYDROGEOXIDOREDUCTASE
Ref.: IDENTIFICATION OF THE ELUSIVE PYRUVATE REDUCTASE OF CHLAMYDOMONAS REINHARDTII CHLOROPLASTS. PLANT CELL.PHYSIOL. V. 57 82 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NAD H:1000;
F:1000;
C:1000;
B:1000;
D:1000;
G:1000;
A:1000;
E:1000;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
663.425 C21 H27 N7 O14 P2 c1cc(...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4ZGS 2.46 Å EC: 1.-.-.- IDENTIFICATION OF THE PYRUVATE REDUCTASE OF CHLAMYDOMONAS RE CHLAMYDOMONAS REINHARDTII PYRUVATE DEHYDROGENASE FERMENTATION GREEN ALGA BIOHYDROGEOXIDOREDUCTASE
Ref.: IDENTIFICATION OF THE ELUSIVE PYRUVATE REDUCTASE OF CHLAMYDOMONAS REINHARDTII CHLOROPLASTS. PLANT CELL.PHYSIOL. V. 57 82 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 318 families.
1 4ZGS - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 280 families.
1 4ZGS - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1J49 - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
2 5Z21 - NAI C21 H29 N7 O14 P2 c1nc(c2c(n....
3 5Z20 - OXM C2 H3 N O3 C(=O)(C(=O....
4 4ZGS - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: NAD; Similar ligands found: 230
No: Ligand ECFP6 Tc MDL keys Tc
1 A3D 0.872727 0.986111
2 NHD 0.821429 0.972222
3 NAP 0.811966 0.986111
4 NFD 0.791304 0.946667
5 NXX 0.765766 0.972603
6 DND 0.765766 0.972603
7 AMP NAD 0.74359 0.972222
8 ZID 0.737705 0.986111
9 NAQ 0.729508 0.934211
10 NAE 0.721311 0.959459
11 NA0 0.712 0.972603
12 TAP 0.704 0.921053
13 NDE 0.689922 0.972603
14 NAJ 0.683333 0.972222
15 NDC 0.679389 0.934211
16 NDO 0.674603 0.958904
17 N01 0.656 0.972222
18 CNA 0.642276 0.972603
19 NBP 0.621212 0.922078
20 8ID 0.609756 0.922078
21 A2D 0.576923 0.958333
22 ADP 0.575472 0.931507
23 NGD 0.574803 0.922078
24 BA3 0.566038 0.958333
25 M33 0.564815 0.918919
26 ADP PO3 0.563636 0.957747
27 B4P 0.560748 0.958333
28 AP5 0.560748 0.958333
29 AN2 0.555556 0.918919
30 AT4 0.555556 0.894737
31 GAP 0.553571 0.932432
32 OOB 0.551724 0.972222
33 CA0 0.550459 0.932432
34 9JJ 0.546053 0.898734
35 HEJ 0.545455 0.931507
36 ACP 0.545455 0.906667
37 ATP 0.545455 0.931507
38 DQV 0.544 0.972222
39 ADP ALF 0.54386 0.883117
40 ALF ADP 0.54386 0.883117
41 DAL AMP 0.543103 0.945205
42 APR 0.540541 0.931507
43 AQP 0.540541 0.931507
44 AR6 0.540541 0.931507
45 5FA 0.540541 0.931507
46 ADP VO4 0.53913 0.945205
47 VO4 ADP 0.53913 0.945205
48 AD9 0.535714 0.906667
49 SAP 0.535714 0.883117
50 AGS 0.535714 0.883117
51 WAQ 0.533333 0.896104
52 ABM 0.53271 0.905405
53 DLL 0.529412 0.972222
54 00A 0.529412 0.921053
55 ACQ 0.526316 0.906667
56 NJP 0.526316 0.959459
57 ANP 0.526316 0.906667
58 OAD 0.525 0.932432
59 ADX 0.522523 0.839506
60 5AL 0.521739 0.945205
61 A1R 0.521008 0.871795
62 9SN 0.520325 0.909091
63 A 0.518868 0.930556
64 AMP 0.518868 0.930556
65 50T 0.517857 0.893333
66 ATF 0.517241 0.894737
67 1ZZ 0.516393 0.851852
68 3OD 0.516393 0.932432
69 SON 0.513514 0.92
70 PRX 0.513274 0.881579
71 6YZ 0.512821 0.906667
72 SRP 0.512821 0.92
73 9X8 0.512397 0.883117
74 ADP BMA 0.512397 0.932432
75 3UK 0.512397 0.958904
76 MYR AMP 0.512195 0.851852
77 NAJ PZO 0.510949 0.909091
78 NMN 0.509434 0.875
79 A3R 0.508333 0.871795
80 B5V 0.508197 0.945946
81 AMP DBH 0.507937 0.906667
82 A22 0.504202 0.945205
83 ATP A A A 0.504 0.971831
84 B5M 0.504 0.933333
85 FA5 0.504 0.945946
86 8QN 0.5 0.945205
87 NAX 0.496183 0.886076
88 TYR AMP 0.496063 0.933333
89 PR8 0.495935 0.8625
90 AMO 0.495868 0.92
91 ADQ 0.495868 0.932432
92 4AD 0.495868 0.933333
93 PAJ 0.495868 0.873418
94 A12 0.495495 0.894737
95 AP2 0.495495 0.894737
96 AHZ 0.492308 0.851852
97 YAP 0.492063 0.933333
98 FYA 0.491935 0.918919
99 AHX 0.491803 0.884615
100 4UU 0.488372 0.933333
101 5SV 0.487603 0.8375
102 TAT 0.487179 0.894737
103 T99 0.487179 0.894737
104 APC 0.486957 0.894737
105 SRA 0.486239 0.881579
106 6V0 0.484848 0.909091
107 NAI 0.484848 0.921053
108 GTA 0.484615 0.898734
109 A A 0.483871 0.958333
110 LAD 0.483871 0.873418
111 AU1 0.482456 0.906667
112 F2R 0.481752 0.831325
113 OMR 0.481203 0.841463
114 TXE 0.481203 0.921053
115 AF3 ADP 3PG 0.481203 0.873418
116 LAQ 0.480916 0.851852
117 G3A 0.48062 0.909091
118 B5Y 0.480315 0.933333
119 NB8 0.48 0.884615
120 TXA 0.48 0.92
121 BIS 0.48 0.871795
122 ME8 0.48 0.851852
123 PTJ 0.48 0.884615
124 139 0.477941 0.886076
125 LPA AMP 0.477273 0.851852
126 AFH 0.476923 0.873418
127 AR6 AR6 0.476923 0.958333
128 G5P 0.476923 0.909091
129 ARG AMP 0.476923 0.841463
130 25L 0.47619 0.945205
131 NAJ PYZ 0.475524 0.864198
132 25A 0.47541 0.958333
133 9ZA 0.47541 0.896104
134 9ZD 0.47541 0.896104
135 DZD 0.47482 0.897436
136 TXD 0.473684 0.921053
137 4UV 0.472868 0.933333
138 TYM 0.470149 0.945946
139 RBY 0.470085 0.894737
140 ADV 0.470085 0.894737
141 4TA 0.467626 0.864198
142 48N 0.466165 0.884615
143 XAH 0.465116 0.851852
144 4UW 0.462687 0.897436
145 M24 0.461538 0.886076
146 80F 0.460993 0.853659
147 IOT 0.459854 0.821429
148 T5A 0.456522 0.853659
149 EAD 0.455782 0.886076
150 MAP 0.455285 0.883117
151 GA7 0.454545 0.894737
152 BT5 0.453901 0.821429
153 A4P 0.452555 0.833333
154 UP5 0.451852 0.933333
155 PAP 0.445378 0.917808
156 4TC 0.445255 0.909091
157 AP0 0.445255 0.884615
158 YLP 0.444444 0.831325
159 P1H 0.443709 0.864198
160 AOC 0.442478 0.810811
161 Z5A 0.439189 0.833333
162 LMS 0.4375 0.817073
163 2A5 0.436975 0.857143
164 A G 0.43662 0.921053
165 G A A A 0.43662 0.909091
166 COD 0.43662 0.802326
167 ADJ 0.435714 0.841463
168 YLB 0.434783 0.831325
169 YLC 0.434783 0.851852
170 U A G G 0.433566 0.921053
171 ATR 0.433333 0.90411
172 7MD 0.432836 0.851852
173 8X1 0.432 0.764045
174 G5A 0.429752 0.790698
175 PO4 PO4 A A A A PO4 0.429688 0.943662
176 TAD 0.42963 0.873418
177 5AS 0.42735 0.770115
178 BTX 0.426573 0.831325
179 YLA 0.425532 0.831325
180 DSZ 0.425197 0.790698
181 NCN 0.424779 0.805556
182 UPA 0.42446 0.921053
183 8PZ 0.424242 0.811765
184 VMS 0.424 0.8
185 54H 0.424 0.8
186 9K8 0.423077 0.744444
187 N0B 0.422819 0.853659
188 6AD 0.422764 0.85
189 AYB 0.422535 0.821429
190 7D3 0.422414 0.844156
191 YLY 0.421769 0.821429
192 TSB 0.420635 0.809524
193 ODP 0.41958 0.922078
194 AV2 0.419355 0.855263
195 FB0 0.419355 0.775281
196 A5A 0.419355 0.819277
197 NNR 0.419048 0.739726
198 A A A 0.418605 0.918919
199 U A 0.417808 0.946667
200 649 0.417266 0.775281
201 NMN AMP PO4 0.416667 0.933333
202 SSA 0.416 0.790698
203 P5A 0.415385 0.755556
204 LSS 0.414062 0.772727
205 A2R 0.412698 0.918919
206 52H 0.412698 0.790698
207 JB6 0.412214 0.896104
208 5N5 0.411215 0.783784
209 YSA 0.410448 0.811765
210 53H 0.409449 0.790698
211 5CA 0.409449 0.790698
212 ITT 0.408333 0.878378
213 7D4 0.408333 0.844156
214 NA7 0.407692 0.894737
215 LEU LMS 0.407692 0.784091
216 5CD 0.407407 0.794521
217 0WD 0.406897 0.909091
218 A3P 0.40678 0.930556
219 HFD 0.406504 0.883117
220 AVV 0.40625 0.860759
221 RAB 0.40566 0.808219
222 XYA 0.40566 0.808219
223 ADN 0.40566 0.808219
224 FDA 0.405063 0.823529
225 GSU 0.40458 0.790698
226 7MC 0.404255 0.831325
227 NSS 0.403101 0.811765
228 6FA 0.402516 0.853659
229 PPS 0.4 0.817073
230 NVA LMS 0.4 0.784091
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4ZGS; Ligand: NAD; Similar sites found with APoc: 910
This union binding pocket(no: 1) in the query (biounit: 4zgs.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 5KK4 44E None
2 1PZG A3D 0.906344
3 1UXG FUM 1.2945
4 1UXG NAD 1.2945
5 1YQZ FAD 1.29534
6 1VJT NAD 1.29534
7 5LD5 NAD 1.39665
8 4PVD NDP 1.46199
9 3LZW FAD 1.50602
10 3LZW NAP 1.50602
11 1RYO OXL 1.52905
12 1DLJ UGA 1.5544
13 1DLJ NAI 1.5544
14 1X87 NAD 1.5544
15 1I2B UPG 1.5544
16 1I2B NAD 1.5544
17 1I2B USQ 1.5544
18 1O0S NAI 1.5544
19 5EZ7 FAD 1.5544
20 5I39 FAD 1.5544
21 5FJN FAD 1.5544
22 5FJN BE2 1.5544
23 4CNK FAD 1.5544
24 3S5W FAD 1.5544
25 3S5W NAP 1.5544
26 1LVL NAD 1.5544
27 1LVL FAD 1.5544
28 4WOE 3S5 1.5544
29 2JHF NAD 1.60428
30 1U3U BNF 1.60428
31 1U3U NAD 1.60428
32 4Q9N NAI 1.67785
33 1WPQ NAD 1.7192
34 2DFV NAD 1.72911
35 1ORR NAD 1.72911
36 3I6I NDP 1.7341
37 1UDB NAD 1.77515
38 1UDB UFG 1.77515
39 2NPX NAD 1.81347
40 4TXI FAD 1.81347
41 4RSL FAD 1.81347
42 2GV8 FAD 1.81347
43 2GVC FAD 1.81347
44 1PS9 FAD 1.81347
45 1OBB NAD 1.81347
46 2NPX FAD 1.81347
47 2BRY FAD 1.81347
48 1PS9 NAP 1.81347
49 1VQW FAD 1.81347
50 3C7A NAD 1.81347
51 3NYC IAR 1.83727
52 3NYC FAD 1.83727
53 3AY6 NAI 1.85874
54 3AY6 BGC 1.85874
55 1JAY NAP 1.88679
56 1TDF NAP 1.89873
57 1TDF FAD 1.89873
58 1GEE NAD 1.91571
59 5ZI9 FLC 1.92308
60 1EQ2 NAP 1.93548
61 3AB1 FAD 1.94444
62 5A3B APR 1.9802
63 1RJW ETF 2.0649
64 1V59 FAD 2.07254
65 3QVP FAD 2.07254
66 5TS5 FAD 2.07254
67 1UP7 NAD 2.07254
68 3QFA FAD 2.07254
69 1V59 NAD 2.07254
70 6FP4 FAD 2.07254
71 6FP4 E1T 2.07254
72 4YNU FAD 2.07254
73 4YNU LGC 2.07254
74 5HV7 RBL 2.07254
75 1Z0N BCD 2.08333
76 4IDC 1XX 2.10843
77 4IDC NDP 2.10843
78 4R5M 4NO 2.12766
79 4R5M NAP 2.12766
80 3FPZ AHZ 2.14724
81 2Q7V FAD 2.15385
82 4TQG NDP 2.16718
83 5O4J 9KH 2.18978
84 5O4J PJL 2.18978
85 5O4J SAH 2.18978
86 3DAG FEG 2.23464
87 6BR7 BEF 2.25564
88 1YKF NAP 2.27273
89 2I3G NAP 2.27273
90 5N0J FAD 2.2792
91 6GAR FAD 2.29226
92 3FXU TSU 2.29508
93 2ZAT NAP 2.30769
94 1O6Z NAD 2.31023
95 5YU3 PRO 2.32558
96 5YU3 NAD 2.32558
97 1RM0 D6P 2.33161
98 1RM0 NAI 2.33161
99 1GQ2 NAP 2.33161
100 1Z45 NAD 2.33161
101 1RYD NDP 2.33161
102 5MBX SP5 2.33161
103 5MBX FAD 2.33161
104 1E1M NAP 2.33161
105 1E1M FAD 2.33161
106 3V1U NAD 2.33161
107 1QO8 FAD 2.33161
108 2C7G FAD 2.33161
109 2C7G ODP 2.33161
110 5YB7 FAD 2.33161
111 5TUF TDC 2.33161
112 5YB7 ORN 2.33161
113 4QS9 BGC 2.33161
114 5TUF FAD 2.33161
115 1P31 EPU 2.33161
116 3HDY GDU 2.33161
117 3HDY FDA 2.33161
118 3HDY FAD 2.33161
119 1P3D UMA 2.33161
120 1FK8 NAD 2.33463
121 2Q46 NAP 2.37154
122 1XSE NDP 2.37288
123 4BVA NDP 2.38806
124 4BVA T3 2.38806
125 4RQU NAD 2.4
126 2CFC NAD 2.4
127 1SZ2 BGC 2.40964
128 1P0F NAP 2.41287
129 4MO2 FAD 2.44565
130 4MO2 FDA 2.44565
131 5GZ6 7C3 2.45399
132 5GZ6 NDP 2.45399
133 1Q0H FOM 2.46305
134 1Q0H NDP 2.46305
135 4G5H NAP 2.47934
136 4G5H UD7 2.47934
137 2BKA NDP 2.47934
138 1MO9 FAD 2.48566
139 1MO9 KPC 2.48566
140 2R8Q IBM 2.50696
141 2B5W NAP 2.52101
142 4O1M NAD 2.53968
143 2BQP GLC 2.5641
144 3O26 NDP 2.57235
145 1KOL NAD 2.59067
146 2IZ1 ATR 2.59067
147 5BVA FAD 2.59067
148 1K3T BRZ 2.59067
149 1PN0 FAD 2.59067
150 1PN0 IPH 2.59067
151 5BRT FAD 2.59067
152 5BRT CH9 2.59067
153 2VTD LKM 2.59067
154 4IV9 FAD 2.59067
155 3M89 GSP 2.59067
156 3SSO SAH 2.59067
157 2VZ0 D64 2.61194
158 2VZ0 NAP 2.61194
159 2WD7 NAP 2.61194
160 6DNT NAD 2.61628
161 2GN4 UD1 2.61628
162 2GN4 NDP 2.61628
163 5A1T NAI 2.6393
164 5A1T OXM 2.6393
165 2DTX BMA 2.65152
166 1VI2 NAD 2.66667
167 4GLL NAD 2.67062
168 4ZVV GN0 2.71084
169 4ZVV NAD 2.71084
170 6GAS FAD 2.71903
171 5IN4 GDP 2.74725
172 5IN4 NAP 2.74725
173 5IN4 6CK 2.74725
174 4J7U YTZ 2.77778
175 4J7U NAP 2.77778
176 1D4D FAD 2.7972
177 2PT9 2MH 2.80374
178 2PT9 S4M 2.80374
179 1Z6Z NAP 2.83688
180 5JWC FAD 2.84974
181 5WGR FAD 2.84974
182 2D2I NAP 2.84974
183 1RSG FAD 2.84974
184 1YY5 FAD 2.84974
185 5JAQ NAI 2.84974
186 1Q1R FAD 2.84974
187 1N9G NAP 2.84974
188 1LJ8 NAD 2.84974
189 1M2W NAD 2.84974
190 2BD0 NAP 2.86885
191 3KO8 NAD 2.88462
192 1H9A NAP 2.8866
193 3B1J NAD 2.94985
194 3B20 NAD 2.94985
195 2O07 SPD 2.96053
196 2O07 MTA 2.96053
197 4YUW 4JU 2.96053
198 4YUW S4M 2.96053
199 4GKV NAD 2.97619
200 9LDB NAD 3.01205
201 9LDT NAD 3.01205
202 1J0X NAD 3.01205
203 1GAD NAD 3.0303
204 1LDM NAD 3.03951
205 1V35 NAI 3.03951
206 1JQ3 AAT 3.04054
207 4USQ FAD 3.04709
208 4USR FAD 3.04709
209 6BWL NAD 3.04878
210 1ZEM NAD 3.05344
211 1VM6 NAD 3.07018
212 1NFQ NAI 3.07692
213 2ZB4 NAP 3.08123
214 2ZB4 5OP 3.08123
215 1OAA OAA 3.0888
216 6CI9 NAP 3.0888
217 5UAV NDP 3.10559
218 5UAV TFB 3.10559
219 1UWK URO 3.10881
220 1UWK NAD 3.10881
221 5G3U FDA 3.10881
222 1FEC FAD 3.10881
223 3WQQ IB3 3.10881
224 3WQQ NDP 3.10881
225 4KP7 NAP 3.10881
226 4KP7 1UQ 3.10881
227 1GPE FAD 3.10881
228 5G3U ITW 3.10881
229 4X1B MLI 3.10881
230 2JHP SAH 3.10881
231 5JCM FAD 3.10881
232 5JCM ISD 3.10881
233 4XQC NAD 3.10881
234 1P77 ATR 3.10881
235 4U7W NDP 3.10881
236 5JCM NAD 3.10881
237 4U8P UDP 3.10881
238 4XQC 13D 3.10881
239 4U8P FDA 3.10881
240 4C3Y FAD 3.10881
241 4Y1B NAP 3.10881
242 3VSE SAH 3.10881
243 4C3Y ANB 3.10881
244 2ZB3 NDP 3.11615
245 4RDI ATP 3.125
246 4RDH AMP 3.125
247 4KQW NAP 3.14286
248 2I7C AAT 3.18021
249 1E3I CXF 3.19149
250 5TWB FAD 3.19767
251 1XKQ NDP 3.21429
252 5A04 NDP 3.24484
253 5A04 BGC 3.24484
254 3VYW SAM 3.24675
255 4D79 ATP 3.26087
256 4L8V NAP 3.2641
257 1RM4 NDP 3.2641
258 3OZ2 FAD 3.27456
259 1N1G BCP 3.27869
260 6CEP OXM 3.29341
261 6CEP NAD 3.29341
262 4B4U NAP 3.30033
263 1L7N ALF 3.31754
264 3AYI FAD 3.32871
265 3AYI HCI 3.32871
266 5OVL NAP 3.33333
267 1WVG APR 3.34262
268 1SOW NAD 3.35366
269 1WDK NAD 3.36788
270 1YKJ FAD 3.36788
271 1YKJ PHB 3.36788
272 1H82 GZZ 3.36788
273 1H82 FAD 3.36788
274 3K7M FAD 3.36788
275 1PGP 6PG 3.36788
276 1KNR FAD 3.36788
277 4DSG UDP 3.36788
278 4DSG FAD 3.36788
279 4PIV NDP 3.36788
280 3KLJ FAD 3.37662
281 5KVS NAP 3.37662
282 3GFB NAD 3.42857
283 1GZ6 NAI 3.44828
284 1EZ4 NAD 3.45912
285 2AHR NAP 3.4749
286 4J56 FAD 3.50877
287 4D42 NAP 3.5461
288 4D42 W0I 3.5461
289 5AYV KPL 3.55987
290 5AYV NAP 3.55987
291 1RPN NDP 3.58209
292 4EUE NAI 3.58852
293 4Z0H NAD 3.59281
294 1O5I NAD 3.61446
295 3L9W AMP 3.62694
296 5J5Z FAD 3.62694
297 3UCL NAP 3.62694
298 3UCL CYH 3.62694
299 3UCL FAD 3.62694
300 3L9W GSH 3.62694
301 1DJN ADP 3.62694
302 2ZXI FAD 3.62694
303 1Q9I FAD 3.62694
304 1Q9I TEO 3.62694
305 3DTU DXC 3.62694
306 4RPL FAD 3.62694
307 4RPL 3UC 3.62694
308 5TUK FAD 3.62694
309 2X6T NAP 3.64146
310 5Y1G AKB 3.65854
311 5Y1G NAD 3.65854
312 3H5N ATP 3.68272
313 5T9E NAP 3.69004
314 5EOW FAD 3.7037
315 1D7O TCL 3.7037
316 1D7O NAD 3.7037
317 1XXR MAN 3.72671
318 3C1O NAP 3.73832
319 4YCA NDP 3.7415
320 5ZI2 ADP 3.76812
321 5ZI2 NAD 3.76812
322 1NVM NAD 3.76812
323 3A4V PYR 3.78549
324 3A4V NAD 3.78549
325 2GZ3 NAP 3.82514
326 2AE2 PTO 3.84615
327 2AE2 NAP 3.84615
328 3IT7 TLA 3.84615
329 4NTO 1PW 3.86473
330 3L4S NAD 3.86905
331 3L4S 3PG 3.86905
332 2FKA BEF 3.87597
333 4OOE FOM 3.88601
334 4OOE NDP 3.88601
335 5U8U FAD 3.88601
336 1REO FAD 3.88601
337 5DNK SAH 3.88601
338 3CMC NAD 3.89222
339 3FGZ BEF 3.90625
340 5OVK NDP 3.90625
341 1RYI FAD 3.9267
342 1RYI GOA 3.9267
343 3RJ5 NAD 3.93701
344 1SB8 NAD 3.97727
345 1SB8 UD2 3.97727
346 1ZK4 NAP 3.98406
347 1ZK4 AC0 3.98406
348 1CDO NAD 4.01069
349 5A96 GTP 4.01606
350 5BJX NAD 4.09836
351 5BJX UDP 4.09836
352 2XYQ SAH 4.09836
353 3ABI NAD 4.10959
354 1ZH8 NAP 4.11765
355 5NM7 GLY 4.13534
356 1MV8 NAD 4.14508
357 1MUU NAD 4.14508
358 5X68 FAD 4.14508
359 5HSA FAS 4.14508
360 4EIP FAD 4.14508
361 5KOX FAD 4.14508
362 5KOX RFP 4.14508
363 5NA1 FAD 4.14508
364 2YG3 FAD 4.14508
365 5E4R NAP 4.14508
366 4HXY NDP 4.14508
367 1LCF OXL 4.14508
368 3GDN HBX 4.14508
369 3GDN FAD 4.14508
370 4EIP K2C 4.14508
371 1Q19 SSC 4.14508
372 3VPH NAD 4.19355
373 3VPH OXM 4.19355
374 1GUZ NAD 4.19355
375 5YEC ATP 4.20168
376 3K5I AIR 4.21836
377 1YS4 NAP 4.23729
378 1XCL SAH 4.25532
379 3OID NDP 4.26357
380 5UR0 NAD 4.29799
381 1F8F NAD 4.31267
382 3Q3C NAD 4.34783
383 2B4Q NAP 4.34783
384 1NNU NAD 4.36681
385 1NNU TCT 4.36681
386 3QJ4 FAD 4.38596
387 3WLE NAD 4.39883
388 3OA2 NAD 4.40252
389 2YVF NAD 4.40415
390 2YVF FAD 4.40415
391 2RGJ FAD 4.40415
392 6AIN FAD 4.40415
393 4M52 FAD 4.40415
394 4EDF UPG 4.40415
395 2IID FAD 4.40415
396 2IID PHE 4.40415
397 2A8X FAD 4.40415
398 4M52 M52 4.40415
399 2RGH FAD 4.40415
400 1GET FAD 4.40415
401 1GET NAP 4.40415
402 4AT0 FAD 4.40415
403 5H6S HDH 4.40415
404 5CAE SIN 4.47284
405 5CAE COA 4.47284
406 5X20 NAD 4.48718
407 3RFV NAI 4.49438
408 3RFV 15L 4.49438
409 1VL8 NAP 4.49438
410 1VDC FAD 4.5045
411 1HDR NAD 4.5082
412 1CER NAD 4.53172
413 2PZM UDP 4.54545
414 2PZM NAD 4.54545
415 3MAG SAH 4.56026
416 1ZQ9 SAM 4.5614
417 3HB5 NAP 4.58716
418 2YVJ NAI 4.58716
419 2YVJ FAD 4.58716
420 4JBI NDP 4.59459
421 2HNK SAH 4.60251
422 1X1T NAD 4.61538
423 5OJI ISN 4.61538
424 5OJI NAP 4.61538
425 3ZV6 4HB 4.62633
426 3ZV6 NAD 4.62633
427 3WXB NDP 4.6595
428 1D1T NAD 4.66321
429 1PJS NAD 4.66321
430 1U8X NAD 4.66321
431 4EMI NAD 4.66321
432 3E1T FAD 4.66321
433 2E5V FAD 4.66321
434 4EMI FAD 4.66321
435 4EMJ FAD 4.66321
436 5EB4 FAD 4.66321
437 5E70 RCD 4.66321
438 4XDZ NDP 4.66472
439 1JNR FAD 4.66667
440 1KEW NAD 4.70914
441 1KEW TYD 4.70914
442 3MCT SAH 4.7138
443 3ITJ FAD 4.73373
444 2DT5 NAD 4.73934
445 1LDN NAD 4.74684
446 2Q1S NAI 4.77454
447 4NTC FAD 4.77612
448 4UP3 NDP 4.77707
449 4UP3 FAD 4.77707
450 1NYT NAP 4.79705
451 4MZU TDR 4.80769
452 5O9F 9ON 4.82955
453 5O9F NAD 4.82955
454 1OC2 TDX 4.88506
455 1OC2 NAD 4.88506
456 1ZBQ NAD 4.89297
457 3H9E NAD 4.91329
458 2HYQ MAN MAN 4.91803
459 2HYR BGC GLC 4.91803
460 2GUD MAN 4.91803
461 2NU5 NAG 4.91803
462 2GUC MAN 4.91803
463 2NUO BGC 4.91803
464 3G5S FAD 4.92228
465 2QA1 FAD 4.92228
466 2IXB NAD 4.92228
467 2GMH FAD 4.92228
468 3ETG GLU 4.92228
469 2HQM FAD 4.92228
470 3ETG GTP 4.92228
471 3ETG NDP 4.92228
472 1GTE FAD 4.92228
473 3NTA FAD 4.92228
474 3NTD FAD 4.92228
475 3NT6 FAD 4.92228
476 2IXB A2G 4.92228
477 3IHG FAD 4.92228
478 3F8D FAD 4.95356
479 5B4T 3HR 5
480 5B4T NAD 5
481 1H2B NAJ 5.01393
482 1LTH NAD 5.01567
483 1P1C SAH 5.02513
484 2C29 NAP 5.04451
485 2C29 DQH 5.04451
486 4K26 NDP 5.07246
487 4K26 SFF 5.07246
488 2Q1W NAD 5.1051
489 1KEV NDP 5.12821
490 1YB5 NAP 5.12821
491 5H81 NAP 5.18135
492 2YY7 NAD 5.18135
493 5BUK FAD 5.18135
494 5MLR NAP 5.18135
495 5MLR GRQ 5.18135
496 3FG2 FAD 5.18135
497 2R4J 13P 5.18135
498 2R4J FAD 5.18135
499 5MSO NAP 5.18135
500 1NAA 6FA 5.18135
501 1CZA GLC 5.18135
502 1NAA ABL 5.18135
503 1NPD NAD 5.20833
504 2IVD FAD 5.23013
505 5VKT NAP 5.24862
506 1YJQ NAP 5.28053
507 1RP0 AHZ 5.28169
508 5JE8 NAD 5.29801
509 1EBF NAD 5.30726
510 4MP8 MLI 5.30973
511 4MP8 NAD 5.30973
512 3A06 NDP 5.31915
513 3A06 FOM 5.31915
514 5FI3 NAP 5.32213
515 1U7T TDT 5.36398
516 1U7T NAD 5.36398
517 2IDO TMP 5.37634
518 1XHL NDP 5.38721
519 5BSH PRO 5.41516
520 1E5Q NDP 5.44041
521 1H6C NDP 5.44041
522 5ZYN FAD 5.44041
523 4BJZ P3A 5.44041
524 4BJZ FAD 5.44041
525 1H6C SIN 5.44041
526 3VZS NAP 5.44747
527 3VZS CAA 5.44747
528 3OJF NDP 5.44747
529 3OJF IMJ 5.44747
530 1E6E FAD 5.46875
531 2DKN NAI 5.4902
532 1HYH NAD 5.50162
533 5MIT NAP 5.50459
534 5MIT FAD 5.50459
535 4OHU NAD 5.53633
536 4OHU 2TK 5.53633
537 2A92 NAI 5.60748
538 3VGL BGC 5.60748
539 1A5Z NAD 5.64263
540 1G0N NDP 5.65371
541 1G0N PHH 5.65371
542 2VYN NAD 5.68862
543 1T26 NAI 5.69948
544 1T26 GBD 5.69948
545 5Y77 FAD 5.69948
546 5MZI FYK 5.69948
547 5MZI FAD 5.69948
548 4MIG G3F 5.69948
549 2XVE FAD 5.69948
550 2VVM FAD 5.69948
551 2VVL FAD 5.69948
552 2CDU FAD 5.69948
553 5OC1 FAD 5.69948
554 5GUD NDP 5.69948
555 2CDU ADP 5.69948
556 5GUD 2IT 5.69948
557 1J78 OLA 5.69948
558 5GUD CIT 5.69948
559 4FRZ ADP 5.69948
560 2DM6 IMN 5.70571
561 2DM6 NAP 5.70571
562 1LSS NAD 5.71429
563 5Y8L NAD 5.76271
564 5Y8L HUI 5.76271
565 4JK3 NAD 5.79151
566 4J4H NAI 5.79151
567 4J4H 1J1 5.79151
568 3B1F NAD 5.86207
569 1NVT NAP 5.92335
570 3QV1 NAD 5.93472
571 4J1Q NDP 5.95855
572 2JB2 PHE 5.95855
573 2JB2 FAD 5.95855
574 1GY8 NAD 5.95855
575 1DSS NAD 6.00601
576 3TWO NDP 6.03448
577 4URF NAD 6.04839
578 3TTM PUT 6.06936
579 5EES NAP 6.07287
580 1EJ0 SAM 6.11111
581 1WMA AB3 6.15942
582 1WMA NDP 6.15942
583 3H8V ATP 6.16438
584 4JNA FAD 6.17647
585 5JY6 NAD 6.17978
586 3AFN NAP 6.20155
587 1DIG NAP 6.20915
588 1DIG L37 6.20915
589 1HDG NAD 6.21762
590 2Y6Q I7T 6.21762
591 2Y6Q FAD 6.21762
592 5XWV 8H6 6.21762
593 5XWV NDP 6.21762
594 1BZL GCG 6.21762
595 1BZL FAD 6.21762
596 3LAD FAD 6.21762
597 4RVG TYD 6.21762
598 4CM9 NAP 6.25
599 4CMI NAP 6.25
600 4CM8 NAP 6.25
601 4CLR NAP 6.25
602 3BMO NAP 6.25
603 3JQA NAP 6.25
604 4CM4 NAP 6.25
605 3JQF NAP 6.25
606 3BMN NAP 6.25
607 3BMQ NAP 6.25
608 3JQ9 NAP 6.25
609 3JQG NAP 6.25
610 1N5D NDP 6.25
611 3JQ7 NAP 6.25
612 4CME NAP 6.25
613 4CLO NAP 6.25
614 4IF4 BEF 6.25
615 3JQ8 NAP 6.25
616 3JQB NAP 6.25
617 5L4S 6KX 6.28931
618 5L4S NAP 6.28931
619 2WSB NAD 6.29921
620 1COY FAD 6.31164
621 1COY AND 6.31164
622 6BJO DUY 6.4
623 5KKA 6V0 6.41026
624 5ZEC NAP 6.43275
625 5L95 AMP 6.45161
626 5KVA SAM 6.47482
627 4MOP 2H5 6.47668
628 4D04 FAD 6.47668
629 4D04 NAP 6.47668
630 3NUG NAD 6.47668
631 1QMG APX 6.47668
632 3O8M GLC 6.47668
633 3O8M BGC 6.47668
634 1BXK NAD 6.47887
635 4J36 1HR 6.50602
636 4J36 FAD 6.50602
637 1NM5 NAD 6.51042
638 1F8G NAD 6.51042
639 2OOR NAD 6.51042
640 1L7E NAI 6.51042
641 5DF1 NAP 6.52174
642 5DF1 58X 6.52174
643 1GR0 NAD 6.53951
644 4ZCC NAI 6.54762
645 4ZCC FAD 6.54762
646 1W8D NAP 6.62252
647 1W73 NAP 6.62252
648 3WGT FAD 6.62824
649 3WGT QSC 6.62824
650 3CH6 NAP 6.64336
651 3CH6 311 6.64336
652 3GGO ENO 6.6879
653 3GGO NAI 6.6879
654 3OJO NAD 6.73575
655 5UAO FAD 6.73575
656 5AHO TLA 6.73575
657 1VBJ CIT 6.76157
658 1I8T FAD 6.81199
659 3HAD NAD 6.81818
660 2CDC XYP 6.8306
661 2CDC XYS 6.8306
662 1YQD NAP 6.8306
663 2CDC NAP 6.8306
664 5K4W THR 6.85358
665 5K4W NAI 6.85358
666 3WBF NAP 6.88525
667 3WBF API 6.88525
668 4KOA NDP 6.90691
669 5NUE NAD 6.92771
670 5NUF NAD 6.92771
671 6A0S NDP 6.92771
672 6A0S HSE 6.92771
673 2GLX NDP 6.92771
674 5DRN 5CT 6.94444
675 4AP3 NAP 6.99482
676 4AP3 FAD 6.99482
677 2DKH FAD 6.99482
678 1Y8Q ATP 6.99482
679 2DKH 3HB 6.99482
680 6F97 FAD 6.99482
681 3AD8 NAD 7.07071
682 3AD8 FAD 7.07071
683 3AD8 PYC 7.07071
684 4HA6 FAD 7.08661
685 1GV0 NAD 7.09677
686 1L5Y BEF 7.09677
687 2GDZ NAD 7.11611
688 3LU1 NAD 7.14286
689 4JDR FAD 7.173
690 3ZNN FAD 7.20461
691 3ZNN 4WL 7.20461
692 4I7E PEP 7.21003
693 5KMS NAD 7.25389
694 2C5A NAD 7.25389
695 2C5A GDC 7.25389
696 5KMS FAD 7.25389
697 3FWN ATR 7.25389
698 6AA8 NAD 7.28477
699 5LOG SAH 7.29614
700 1BW9 NAD 7.30337
701 1BXG NAD 7.30337
702 1LLU NAD 7.30994
703 1C1X NAD 7.32394
704 5JCA NDP 7.39437
705 5JCA FAD 7.39437
706 2G5C NAD 7.47331
707 2QRK AMP 7.51295
708 2RGO FAD 7.51295
709 3CIF NAD 7.52089
710 3CIF G3H 7.52089
711 1V6A TRE 7.53012
712 1W6U NAP 7.61589
713 1CF2 NAP 7.71513
714 5Z2L NDP 7.7551
715 3EGI ADP 7.76699
716 3NKS FAD 7.77202
717 3ULK NDP 7.77202
718 4YKG FAD 7.77202
719 4YKG NAD 7.77202
720 1PL6 NAD 7.86517
721 1PL6 572 7.86517
722 3TTN SPD 7.94118
723 2CVQ NDP 7.95107
724 2XVF FAD 8.03109
725 3X0V FAD 8.03109
726 4DPL NAP 8.07799
727 1F06 NDP 8.125
728 1F06 2NP 8.125
729 3CBG SAH 8.18966
730 1VKO NAD 8.29016
731 2WPF FAD 8.29016
732 2AQJ TRP 8.29016
733 2AQJ FAD 8.29016
734 2WPF WPF 8.29016
735 2CVZ NDP 8.3045
736 4ZRN NAD 8.33333
737 4ZRN UPG 8.33333
738 6BQ6 TER 8.45921
739 5TC4 NAD 8.5443
740 6F3N NAD 8.54922
741 6F3N ADN 8.54922
742 6F3M NAD 8.54922
743 4TM3 FAD 8.54922
744 4A0S NAP 8.54922
745 3V1Y NAD 8.60534
746 1PR9 NAP 8.60656
747 3D3W NAP 8.60656
748 3JYN NDP 8.61539
749 2Q2V NAD 8.62745
750 3O9Z NAD 8.65385
751 3O9Z AKG 8.65385
752 4FC7 NAP 8.66426
753 4FC7 COA 8.66426
754 1H5Q NAP 8.67924
755 1KJ8 GAR 8.69565
756 1OMO NAD 8.69565
757 2HK9 NAP 8.72727
758 2HK9 ATR 8.72727
759 5O42 NAD 8.75912
760 5O42 BGC 8.75912
761 5O42 9JW 8.75912
762 5M67 3D1 8.80829
763 5M67 NAD 8.80829
764 5M67 ADE 8.80829
765 1LC3 NAD 8.84354
766 5ZBC FAD 8.86918
767 1RKX NAD 8.96359
768 1GEG NAD 8.98438
769 2NU8 COA 9.02778
770 5N2I NAP 9.05172
771 3ZOA ACR 9.06736
772 4EA7 COA 9.09091
773 4EA7 JB2 9.09091
774 3SJ7 NDP 9.12698
775 4II2 ATP 9.20245
776 2FR1 NDP 9.25926
777 2Q0L NAP 9.32476
778 2Q0L FAD 9.32476
779 5D4V SAH 9.32836
780 1WP4 NDP 9.34256
781 2F5Z FAD 9.375
782 2FZW NAD 9.38338
783 1X7D ORN 9.42857
784 1X7D NAD 9.42857
785 5X9D 80F 9.53947
786 6F9Q NAD 9.55882
787 1U1I NAD 9.58549
788 1LES GLC FRU 9.61539
789 4D3F NAP 9.67742
790 1FL2 FAD 9.67742
791 2PV7 NAD 9.73154
792 1GZ4 ATP 9.84456
793 4REP FAD 9.84456
794 1A99 PUT 9.88372
795 3O03 NAP 9.96564
796 6EL3 NAP 9.97375
797 5W3K 9TY 10
798 5W3K NDP 10
799 4XDY NAI 10.0592
800 3H4V NAP 10.0694
801 3H4V DVP 10.0694
802 2NVK FAD 10.1036
803 2NVK NAP 10.1036
804 3RNM FAD 10.3448
805 1R6D NAD 10.3858
806 1R6D DAU 10.3858
807 1OFS SUC 10.4167
808 4NBT NAD 10.4167
809 1FWV SGA MAG FUC 10.4478
810 4JJF N2I 10.4651
811 4JJF FE9 10.4651
812 1HYE NAP 10.5431
813 1C3V NDP 10.6122
814 5TQZ GLC 10.6667
815 3NGL NAP 10.8696
816 5TOW ADN 10.8808
817 5TOW NAI 10.8808
818 4OPC FDA 10.8808
819 4OPC PGT 10.8808
820 1C0I FAD 11.0193
821 1C0I BE2 11.0193
822 1LOB MMA 11.0497
823 1E3W NAD 11.1111
824 1E6W NAD 11.1538
825 2VT3 ATP 11.1628
826 2B4R NAD 11.3043
827 2B4R AES 11.3043
828 1TB4 PEJ 11.3208
829 1ZK7 FAD 11.399
830 3SQP FAD 11.5063
831 1E7S NAP 11.5265
832 4W6Z 8ID 11.5274
833 1KYQ NAD 11.6788
834 1LUA NAP 11.8467
835 4ZA2 NAD 11.8577
836 2ZJ1 ARJ 11.9171
837 2ZJ1 NAD 11.9171
838 1Z82 NDP 11.9403
839 1QH9 LAC 12.069
840 1R37 NAD 12.1037
841 2F1K NAP 12.1864
842 1X14 NAD 12.6943
843 4QED NAP 12.9032
844 1O94 ADP 13.2576
845 6EQS BV8 13.4545
846 1N7G GDR 13.4715
847 1N7G NDP 13.4715
848 3NDJ SAH 13.4715
849 3NDJ JHZ 13.4715
850 2YYY NAP 13.7026
851 5EJ2 NAD 13.7306
852 5DOZ NDP 13.9053
853 5T9F NAP 14.0221
854 5T9F TYR 14.0221
855 3WV8 ATP 14.2202
856 4YSX FAD 14.3617
857 4MDH NAD 14.3713
858 5MDH NAD 14.4144
859 2RH4 EMO 14.4404
860 3QWI NAP 14.4444
861 3QWI CUE 14.4444
862 5EIN NAP 14.8148
863 5ZZ6 ADP 14.9038
864 5ZZ6 NAD 14.9038
865 5ODQ FAD 15
866 1DRV A3D 15.0183
867 2VHW NAI 15.1194
868 1EK6 NAI 15.2299
869 1EK6 UPG 15.2299
870 1WOQ BGC 15.544
871 2EV9 SKM 15.5894
872 2EV9 NAP 15.5894
873 2HMT NAI 15.9722
874 1AE1 NAP 16.1172
875 4TSK NDP 16.2857
876 1V8B NAD 16.3212
877 3ICC NAP 16.4706
878 4CJX NAP 17.5549
879 1Q7B NAP 17.623
880 1SAY PYR 17.7285
881 5OOH 9ZZ 18.4466
882 5OOH NAP 18.4466
883 2DC1 NAD 19.0678
884 3NJ4 AFX 20
885 3NJ4 NAD 20
886 4XZ3 COA 20.4348
887 1I36 NAP 20.8333
888 4XYM COA 20.8696
889 1J5P NAD 22.5296
890 3ORF NAD 23.506
891 2BOS GLA GAL GLC NBU 23.5294
892 4CQM NAP 23.7705
893 4XYB NDP 26.087
894 3OND ADN 26.6839
895 3OND NAD 26.6839
896 5DN9 NAD 28.5714
897 2O4C NAD 29.4737
898 2NAD NAD 33.1606
899 1SC6 NAD 33.1606
900 2GSD NAD 33.4197
901 1HKU NAD 33.7989
902 2DBZ NAP 36.8263
903 5AOV NAP 37.2024
904 6BII NAP 38.1381
905 5N6C NAD 38.6667
906 3BAZ NAP 41.7417
907 2GCG NDP 43.0303
908 2VOH CIT 46.1538
909 3KB6 NAD 46.7066
910 5OFW 9TW 47.9821
Pocket No.: 2; Query (leader) PDB : 4ZGS; Ligand: NAD; Similar sites found with APoc: 24
This union binding pocket(no: 2) in the query (biounit: 4zgs.bio1) has 24 residues
No: Leader PDB Ligand Sequence Similarity
1 1OFL NGK GCD 1.29534
2 2GV8 NDP 1.81347
3 3OIG NAD 2.63158
4 4WAS NAP 3.2967
5 5KVS 6XR 3.37662
6 2AWN ADP 3.93701
7 1KNY KAN 3.95257
8 1LVW TYD 4.40678
9 5FII PHE 4.90196
10 2GUD BMA 4.91803
11 1A27 NAP 5.19031
12 4LHD GLY 5.44041
13 1C3M MAN MAN 5.44218
14 2GN3 MAN 5.55556
15 2GN3 MMA 5.55556
16 4X3R 686 5.69948
17 2J5V PCA 5.99455
18 3HVJ 705 6.33484
19 1NM5 NAP 6.51042
20 1QG6 NAD 6.89655
21 1QG6 TCL 6.89655
22 3GF4 UPG 8.03109
23 3GF4 FAD 8.03109
24 3GD8 GOL 8.07175
Pocket No.: 3; Query (leader) PDB : 4ZGS; Ligand: NAD; Similar sites found with APoc: 18
This union binding pocket(no: 3) in the query (biounit: 4zgs.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 2ZWS PLM 1.29534
2 3LRE ADP 1.69014
3 3KC1 2T6 2.07715
4 2BES RES 2.32558
5 1OUK 084 2.45902
6 2YN4 39J 2.54237
7 5TG5 JW8 2.85714
8 5KQA GSH 3.78788
9 3KCC CMP 3.84615
10 6GR0 F8W 4.02299
11 5VLQ ANP 4.14508
12 4XFR CIT 5.18135
13 5YLF BGC 5.68862
14 3ZOK GLY 5.82011
15 1Y7P RIP 7.17489
16 3B8I OXL 8.03109
17 6MJ7 ARG 10.9091
18 3LQV ADE 15.3846
Pocket No.: 4; Query (leader) PDB : 4ZGS; Ligand: NAD; Similar sites found with APoc: 23
This union binding pocket(no: 4) in the query (biounit: 4zgs.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 2AOT SAH 1.71233
2 3FPF TNA 2.34899
3 3FPF MTA 2.34899
4 5KJW 53C 2.59067
5 4XCZ T3Q 2.84974
6 2J0B UDP 2.85714
7 5T2Y 753 3.0303
8 3GRU AMP 3.05085
9 2EUG URA 3.49345
10 2VDF OCT 3.55731
11 5OFI 9TQ 4.09836
12 5UIJ TYD 4.66321
13 1G4U AF3 4.8913
14 5TV6 PML 5
15 2WQ4 SFU 5.12821
16 5G6U TRP 6.13027
17 2ZL4 ALA ALA ALA ALA 6.63265
18 3QPB