Receptor
PDB id Resolution Class Description Source Keywords
4kil 1.75 Å EC: 2.-.-.- 7-(4-FLUOROPHENYL)-3-HYDROXYQUINOLIN-2(1H)-ONE BOUND TO INFL H1N1 ENDONUCLEASE INFLUENZA A VIRUS (A/LIMA/WRAIR1695P/2009(H1N1)) ENDONUCLEASE CAP-SNATCHING INFLUENZA RNA BINDING PROTEIN-COMPLEX
Ref.: 3-HYDROXYQUINOLIN-2(1H)-ONES AS INHIBITORS OF INFLU ENDONUCLEASE. ACS MED CHEM LETT V. 4 547 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
EDO A:304;
 Invalid;
 none;
 submit data
62.068 C2 H6 O2 C(CO)...
1R5 A:305;
 Valid;
 none;
 ic50 = 0.5 uM
255.244 C15 H10 F N O2 c1cc(...
MN A:302;
A:301;
 Part of Protein;
Part of Protein;
 none;
none;
 submit data
54.938 Mn [Mn+2...
SO4 A:303;
 Invalid;
 none;
 submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4KIL 1.75 Å EC: 2.-.-.- 7-(4-FLUOROPHENYL)-3-HYDROXYQUINOLIN-2(1H)-ONE BOUND TO INFL H1N1 ENDONUCLEASE INFLUENZA A VIRUS (A/LIMA/WRAIR1695P/2009(H1N1)) ENDONUCLEASE CAP-SNATCHING INFLUENZA RNA BINDING PROTEIN-COMPLEX
Ref.: 3-HYDROXYQUINOLIN-2(1H)-ONES AS INHIBITORS OF INFLU ENDONUCLEASE. ACS MED CHEM LETT V. 4 547 2013
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 313 families.
1 4AWF ic50 = 2.7 uM XI7 C10 H8 O4 c1ccc(cc1)....
2 4KIL ic50 = 0.5 uM 1R5 C15 H10 F N O2 c1cc(ccc1c....
70% Homology Family (69)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 25 families.
1 5D42 - TMP C10 H15 N2 O8 P CC1=CN(C(=....
2 4YYL ic50 = 9.7 uM 4KN C14 H11 F O5 c1cc(ccc1O....
3 5WDN - G1K C17 H17 N3 O6 c1ccc(cc1)....
4 4ZI0 - 4P9 C13 H11 Cl N2 O3 c1cc(ccc1N....
5 4AWK ic50 = 0.13 uM CI1 C23 H24 Cl N O6 S c1ccc(cc1)....
6 5WE9 Ki = 0.06 uM GY7 C24 H22 F2 N4 O4 c1ccc(cc1)....
7 6E0Q ic50 = 8 nM HKD C9 H8 O5 CC1=C(C=C(....
8 5CL0 - U5P C9 H13 N2 O9 P C1=CN(C(=O....
9 6DCY ic50 = 3.5 uM G5V C7 H6 O5 CC1=C(C(=O....
10 5CCY - TMP C10 H15 N2 O8 P CC1=CN(C(=....
11 4AVL - TMP C10 H15 N2 O8 P CC1=CN(C(=....
12 4AVG ic50 = 0.06 uM SL6 C23 H30 Cl N O4 c1cc(ccc1C....
13 6FS6 - E4Z C24 H19 F2 N3 O4 S c1ccc2c(c1....
14 5W44 Ki = 0.36 uM GY6 C24 H22 Cl2 N4 O4 c1ccc(cc1)....
15 5WEF Ki = 0.36 uM GY6 C24 H22 Cl2 N4 O4 c1ccc(cc1)....
16 5I13 - 4P9 C13 H11 Cl N2 O3 c1cc(ccc1N....
17 4E5L - DBH C7 H6 O4 c1cc(c(c(c....
18 5D9J Kd = 22 nM 0N8 C23 H24 Cl N O4 c1ccc(cc1)....
19 6FS7 - E4Z C24 H19 F2 N3 O4 S c1ccc2c(c1....
20 5W3I Ki = 1.6 uM GY5 C20 H24 N4 O6 COCCNC(=O)....
21 4E5F ic50 = 15 uM 0N7 C9 H7 N O3 c1ccc2c(c1....
22 5EGA ic50 = 8.7 uM GK0 C14 H12 N2 O7 c1c(cc(c(c....
23 6YA5 ic50 = 0.072 uM LU2 C15 H10 O6 c1cc(c(cc1....
24 6YEM ic50 = 0.29 uM OOH C15 H14 O7 CCCCC(=O)C....
25 6DZQ ic50 = 0.043 uM HJP C7 H6 O5 CC1=CC(=O)....
26 5W7U Ki = 0.009 uM GY8 C24 H21 Cl2 N5 O4 c1ccc2c(c1....
27 4LN7 ic50 = 0.041 uM 1ZQ C17 H11 F2 N O2 c1cc(ccc1c....
28 4E5J Ki = 18.7 uM 581 C13 H11 N3 O5 CC(=O)Nc1c....
29 4E5H ic50 = 0.43 uM 0N8 C23 H24 Cl N O4 c1ccc(cc1)....
30 5WCT - GY4 C17 H16 Cl N3 O5 c1cc(ccc1C....
31 5FDG - 0N8 C23 H24 Cl N O4 c1ccc(cc1)....
32 4ZHZ - 4P8 C14 H10 Cl N O4 c1ccc(c(c1....
33 4AWH - U5P C9 H13 N2 O9 P C1=CN(C(=O....
34 5WA7 Ki = 0.4 uM KU4 C26 H27 Cl N4 O5 c1ccc(cc1)....
35 5WG9 Ki = 2.6 uM KU4 C26 H27 Cl N4 O5 c1ccc(cc1)....
36 5VRJ - R07 C24 H20 F3 N3 O3 S C[C@H](C(F....
37 5VQN - R07 C24 H20 F3 N3 O3 S C[C@H](C(F....
38 5W92 Ki = 0.02 uM KU0 C23 H21 Cl2 N5 O6 S c1ccc(cc1)....
39 5WEI Ki = 2 uM GY6 C24 H22 Cl2 N4 O4 c1ccc(cc1)....
40 5VPX Kd = 4.6 uM R07 C24 H20 F3 N3 O3 S C[C@H](C(F....
41 5WDC Ki = 0.4 uM G2K C25 H25 Cl N4 O5 c1ccc(cc1)....
42 5WEB Ki = 0.01 uM KU5 C25 H25 Cl N4 O6 S2 c1ccc(cc1)....
43 5WB3 Ki = 0.06 uM GYA C28 H29 Cl N4 O6 S COc1cc2c(c....
44 5VPT Kd = 9.5 nM R07 C24 H20 F3 N3 O3 S C[C@H](C(F....
45 5DEB - U5P C9 H13 N2 O9 P C1=CN(C(=O....
46 5W9G Ki = 0.15 uM KU2 C25 H25 Cl N4 O5 S c1ccc(cc1)....
47 5WAP Ki = 0.3 uM KU9 C26 H25 Cl N4 O4 S c1ccc2c(c1....
48 5WDW Ki = 0.29 uM 8KU C26 H25 Cl N4 O5 S c1ccc2c(c1....
49 5D8U Kd = 949 nM 0N8 C23 H24 Cl N O4 c1ccc(cc1)....
50 5W73 Ki = 0.5 uM GY9 C25 H25 Cl N4 O6 c1ccc(cc1)....
51 5WFW Ki = 0.8 uM GYA C28 H29 Cl N4 O6 S COc1cc2c(c....
52 5WFM Ki = 0.3 uM KU5 C25 H25 Cl N4 O6 S2 c1ccc(cc1)....
53 5WF3 Ki = 1.4 uM KU2 C25 H25 Cl N4 O5 S c1ccc(cc1)....
54 5WFZ Ki < 0.01 uM KU0 C23 H21 Cl2 N5 O6 S c1ccc(cc1)....
55 4M5R ic50 = 1000 uM MSR C9 H8 N2 O c1cc(ccc1n....
56 4M4Q ic50 = 0.011 uM 21A C18 H12 F N5 O2 c1cc(ccc1c....
57 4MK1 ic50 = 16 uM 27Y C5 H4 Br N O2 C1=C(C(=O)....
58 4M5O ic50 = 0.38 uM X48 C11 H9 N O2 c1ccc(cc1)....
59 6NEM ic50 = 12 nM KKS C23 H17 N5 O2 c1ccc2c(c1....
60 4MK5 ic50 = 0.45 uM 28A C12 H11 N O3 COc1cccc(c....
61 4M5U ic50 = 0.023 uM 20F C18 H12 F N5 O2 c1cc(ccc1c....
62 6NEL ic50 = 11 nM KKV C18 H12 F N O4 c1cc(ccc1C....
63 4W9S ic50 = 0.15 uM 3K1 C11 H8 N6 O2 c1cc(ccc1c....
64 4MK2 ic50 = 0.73 uM 28B C12 H8 N2 O2 c1cc(cc(c1....
65 4AWF ic50 = 2.7 uM XI7 C10 H8 O4 c1ccc(cc1)....
66 4KIL ic50 = 0.5 uM 1R5 C15 H10 F N O2 c1cc(ccc1c....
67 3HW4 - TMP C10 H15 N2 O8 P CC1=CN(C(=....
68 3HW3 - U5P C9 H13 N2 O9 P C1=CN(C(=O....
69 3HW5 - AMP C10 H14 N5 O7 P c1nc(c2c(n....
50% Homology Family (71)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 22 families.
1 5D42 - TMP C10 H15 N2 O8 P CC1=CN(C(=....
2 4YYL ic50 = 9.7 uM 4KN C14 H11 F O5 c1cc(ccc1O....
3 5WDN - G1K C17 H17 N3 O6 c1ccc(cc1)....
4 4ZI0 - 4P9 C13 H11 Cl N2 O3 c1cc(ccc1N....
5 4AWK ic50 = 0.13 uM CI1 C23 H24 Cl N O6 S c1ccc(cc1)....
6 5WE9 Ki = 0.06 uM GY7 C24 H22 F2 N4 O4 c1ccc(cc1)....
7 6E0Q ic50 = 8 nM HKD C9 H8 O5 CC1=C(C=C(....
8 5CL0 - U5P C9 H13 N2 O9 P C1=CN(C(=O....
9 6DCY ic50 = 3.5 uM G5V C7 H6 O5 CC1=C(C(=O....
10 5CCY - TMP C10 H15 N2 O8 P CC1=CN(C(=....
11 4AVL - TMP C10 H15 N2 O8 P CC1=CN(C(=....
12 4AVG ic50 = 0.06 uM SL6 C23 H30 Cl N O4 c1cc(ccc1C....
13 6FS6 - E4Z C24 H19 F2 N3 O4 S c1ccc2c(c1....
14 5W44 Ki = 0.36 uM GY6 C24 H22 Cl2 N4 O4 c1ccc(cc1)....
15 5WEF Ki = 0.36 uM GY6 C24 H22 Cl2 N4 O4 c1ccc(cc1)....
16 5I13 - 4P9 C13 H11 Cl N2 O3 c1cc(ccc1N....
17 4E5L - DBH C7 H6 O4 c1cc(c(c(c....
18 5D9J Kd = 22 nM 0N8 C23 H24 Cl N O4 c1ccc(cc1)....
19 6FS7 - E4Z C24 H19 F2 N3 O4 S c1ccc2c(c1....
20 5W3I Ki = 1.6 uM GY5 C20 H24 N4 O6 COCCNC(=O)....
21 4E5F ic50 = 15 uM 0N7 C9 H7 N O3 c1ccc2c(c1....
22 5EGA ic50 = 8.7 uM GK0 C14 H12 N2 O7 c1c(cc(c(c....
23 6YA5 ic50 = 0.072 uM LU2 C15 H10 O6 c1cc(c(cc1....
24 6YEM ic50 = 0.29 uM OOH C15 H14 O7 CCCCC(=O)C....
25 6DZQ ic50 = 0.043 uM HJP C7 H6 O5 CC1=CC(=O)....
26 5W7U Ki = 0.009 uM GY8 C24 H21 Cl2 N5 O4 c1ccc2c(c1....
27 4LN7 ic50 = 0.041 uM 1ZQ C17 H11 F2 N O2 c1cc(ccc1c....
28 4E5J Ki = 18.7 uM 581 C13 H11 N3 O5 CC(=O)Nc1c....
29 4E5H ic50 = 0.43 uM 0N8 C23 H24 Cl N O4 c1ccc(cc1)....
30 5WCT - GY4 C17 H16 Cl N3 O5 c1cc(ccc1C....
31 5FDG - 0N8 C23 H24 Cl N O4 c1ccc(cc1)....
32 4ZHZ - 4P8 C14 H10 Cl N O4 c1ccc(c(c1....
33 4AWH - U5P C9 H13 N2 O9 P C1=CN(C(=O....
34 5WA7 Ki = 0.4 uM KU4 C26 H27 Cl N4 O5 c1ccc(cc1)....
35 5WG9 Ki = 2.6 uM KU4 C26 H27 Cl N4 O5 c1ccc(cc1)....
36 5VRJ - R07 C24 H20 F3 N3 O3 S C[C@H](C(F....
37 5VQN - R07 C24 H20 F3 N3 O3 S C[C@H](C(F....
38 5W92 Ki = 0.02 uM KU0 C23 H21 Cl2 N5 O6 S c1ccc(cc1)....
39 5WEI Ki = 2 uM GY6 C24 H22 Cl2 N4 O4 c1ccc(cc1)....
40 5VPX Kd = 4.6 uM R07 C24 H20 F3 N3 O3 S C[C@H](C(F....
41 5WDC Ki = 0.4 uM G2K C25 H25 Cl N4 O5 c1ccc(cc1)....
42 5WEB Ki = 0.01 uM KU5 C25 H25 Cl N4 O6 S2 c1ccc(cc1)....
43 5WB3 Ki = 0.06 uM GYA C28 H29 Cl N4 O6 S COc1cc2c(c....
44 5VPT Kd = 9.5 nM R07 C24 H20 F3 N3 O3 S C[C@H](C(F....
45 5DEB - U5P C9 H13 N2 O9 P C1=CN(C(=O....
46 5W9G Ki = 0.15 uM KU2 C25 H25 Cl N4 O5 S c1ccc(cc1)....
47 5WAP Ki = 0.3 uM KU9 C26 H25 Cl N4 O4 S c1ccc2c(c1....
48 5WDW Ki = 0.29 uM 8KU C26 H25 Cl N4 O5 S c1ccc2c(c1....
49 5D8U Kd = 949 nM 0N8 C23 H24 Cl N O4 c1ccc(cc1)....
50 5W73 Ki = 0.5 uM GY9 C25 H25 Cl N4 O6 c1ccc(cc1)....
51 5WFW Ki = 0.8 uM GYA C28 H29 Cl N4 O6 S COc1cc2c(c....
52 5WFM Ki = 0.3 uM KU5 C25 H25 Cl N4 O6 S2 c1ccc(cc1)....
53 5WF3 Ki = 1.4 uM KU2 C25 H25 Cl N4 O5 S c1ccc(cc1)....
54 5WFZ Ki < 0.01 uM KU0 C23 H21 Cl2 N5 O6 S c1ccc(cc1)....
55 4M5R ic50 = 1000 uM MSR C9 H8 N2 O c1cc(ccc1n....
56 4M4Q ic50 = 0.011 uM 21A C18 H12 F N5 O2 c1cc(ccc1c....
57 4MK1 ic50 = 16 uM 27Y C5 H4 Br N O2 C1=C(C(=O)....
58 4M5O ic50 = 0.38 uM X48 C11 H9 N O2 c1ccc(cc1)....
59 6NEM ic50 = 12 nM KKS C23 H17 N5 O2 c1ccc2c(c1....
60 4MK5 ic50 = 0.45 uM 28A C12 H11 N O3 COc1cccc(c....
61 4M5U ic50 = 0.023 uM 20F C18 H12 F N5 O2 c1cc(ccc1c....
62 6NEL ic50 = 11 nM KKV C18 H12 F N O4 c1cc(ccc1C....
63 4W9S ic50 = 0.15 uM 3K1 C11 H8 N6 O2 c1cc(ccc1c....
64 4MK2 ic50 = 0.73 uM 28B C12 H8 N2 O2 c1cc(cc(c1....
65 6FS9 - E4Z C24 H19 F2 N3 O4 S c1ccc2c(c1....
66 6FS8 - E4Z C24 H19 F2 N3 O4 S c1ccc2c(c1....
67 4AWF ic50 = 2.7 uM XI7 C10 H8 O4 c1ccc(cc1)....
68 4KIL ic50 = 0.5 uM 1R5 C15 H10 F N O2 c1cc(ccc1c....
69 3HW4 - TMP C10 H15 N2 O8 P CC1=CN(C(=....
70 3HW3 - U5P C9 H13 N2 O9 P C1=CN(C(=O....
71 3HW5 - AMP C10 H14 N5 O7 P c1nc(c2c(n....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 1R5; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 1R5 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: 1R5; Similar ligands found: 355
No: Ligand Similarity coefficient
1 D64 0.9610
2 1HP 0.9521
3 G2V 0.9511
4 LIG 0.9437
5 5ZM 0.9421
6 OSY 0.9420
7 GEN 0.9413
8 DFV 0.9394
9 HMO 0.9381
10 3F4 0.9369
11 RGK 0.9362
12 SZ5 0.9361
13 CR4 0.9360
14 BMZ 0.9360
15 122 0.9360
16 3WL 0.9351
17 O9T 0.9348
18 LU2 0.9339
19 27F 0.9336
20 08C 0.9334
21 120 0.9332
22 121 0.9329
23 801 0.9329
24 D26 0.9321
25 25F 0.9320
26 NKI 0.9318
27 E9L 0.9307
28 HWB 0.9304
29 22M 0.9304
30 DFL 0.9303
31 7EH 0.9300
32 3TI 0.9297
33 O9Z 0.9294
34 D25 0.9287
35 NVS 0.9287
36 HUL 0.9285
37 CDJ 0.9285
38 0MB 0.9280
39 6DQ 0.9276
40 QUE 0.9270
41 W8L 0.9265
42 NAR 0.9264
43 97K 0.9264
44 RF2 0.9257
45 H2W 0.9247
46 Q8D 0.9239
47 PIQ 0.9237
48 VT3 0.9230
49 0DF 0.9223
50 91F 0.9222
51 MYU 0.9220
52 AGI 0.9220
53 4CN 0.9216
54 A9B 0.9216
55 M3W 0.9210
56 M16 0.9206
57 E92 0.9205
58 6H2 0.9203
59 F36 0.9201
60 20D 0.9198
61 J8D 0.9197
62 AP6 0.9193
63 2OX 0.9189
64 WLH 0.9186
65 KMP 0.9183
66 SAK 0.9182
67 1V1 0.9180
68 E98 0.9178
69 124 0.9173
70 OA4 0.9172
71 1UZ 0.9169
72 ZTW 0.9163
73 OLU 0.9162
74 A73 0.9159
75 1V4 0.9157
76 135 0.9157
77 E8Z 0.9156
78 L2K 0.9155
79 6BK 0.9153
80 A63 0.9150
81 35K 0.9145
82 LI7 0.9142
83 EES 0.9133
84 5EZ 0.9131
85 7G2 0.9130
86 6JP 0.9130
87 C0V 0.9129
88 1V3 0.9125
89 4P9 0.9123
90 O53 0.9114
91 E6Q 0.9100
92 F40 0.9090
93 39R 0.9088
94 68C 0.9087
95 5WW 0.9087
96 H75 0.9086
97 F5N 0.9081
98 TFX 0.9079
99 6JM 0.9077
100 U55 0.9077
101 HPX 0.9075
102 4UM 0.9075
103 DQH 0.9074
104 C4E 0.9071
105 7FZ 0.9064
106 1V0 0.9064
107 0UL 0.9060
108 AX1 0.9060
109 5XM 0.9058
110 NU3 0.9058
111 L02 0.9049
112 TEF 0.9048
113 90M 0.9043
114 0NJ 0.9043
115 397 0.9041
116 BXS 0.9037
117 NIF 0.9032
118 245 0.9028
119 4L2 0.9028
120 RKY 0.9028
121 1V8 0.9026
122 SJR 0.9025
123 O9Q 0.9024
124 A64 0.9023
125 WG8 0.9022
126 LC1 0.9022
127 FSE 0.9019
128 OUG 0.9019
129 FCW 0.9017
130 AD6 0.9016
131 BSU 0.9016
132 1UT 0.9015
133 DX8 0.9013
134 AO 0.9008
135 802 0.9003
136 SDN 0.9002
137 CIU 0.8991
138 20N 0.8988
139 J84 0.8988
140 YZ9 0.8987
141 29F 0.8986
142 IRH 0.8986
143 5B2 0.8985
144 OUA 0.8983
145 4FC 0.8983
146 1UR 0.8981
147 J8G 0.8979
148 2JX 0.8977
149 79X 0.8976
150 3XL 0.8970
151 XZ1 0.8969
152 Y27 0.8969
153 SU9 0.8966
154 MRI 0.8961
155 HH6 0.8954
156 2P3 0.8952
157 1Q1 0.8950
158 272 0.8949
159 5NN 0.8944
160 MBT 0.8943
161 DEH 0.8942
162 CUE 0.8937
163 DX2 0.8936
164 ESJ 0.8934
165 52F 0.8934
166 HCC 0.8932
167 LZ7 0.8932
168 22T 0.8929
169 31F 0.8928
170 SLX 0.8928
171 5TO 0.8925
172 STL 0.8925
173 JVD 0.8924
174 JVB 0.8920
175 4ZF 0.8916
176 8M5 0.8914
177 A9E 0.8910
178 NYJ 0.8910
179 3GX 0.8908
180 BJ4 0.8904
181 9EG 0.8900
182 XAV 0.8896
183 NAL 0.8895
184 1GV 0.8892
185 JKN 0.8892
186 LVY 0.8889
187 F08 0.8888
188 Q12 0.8886
189 4KN 0.8883
190 06R 0.8882
191 W2E 0.8881
192 833 0.8881
193 DX7 0.8879
194 UN9 0.8878
195 P4L 0.8877
196 M4N 0.8875
197 KU1 0.8875
198 3G5 0.8874
199 BVB 0.8872
200 1Q2 0.8870
201 J38 0.8869
202 S0D 0.8868
203 LWA 0.8867
204 3CA 0.8867
205 MYC 0.8864
206 IY5 0.8863
207 K97 0.8861
208 TID 0.8855
209 J2N 0.8852
210 7FC 0.8851
211 2ZI 0.8851
212 0K7 0.8850
213 AZB 0.8849
214 UAY 0.8848
215 123 0.8845
216 OSJ 0.8840
217 HDI 0.8838
218 HPK 0.8836
219 SGW 0.8836
220 5ER 0.8832
221 9CE 0.8831
222 X2L 0.8828
223 B7H 0.8824
224 5ET 0.8823
225 MKN 0.8820
226 5TU 0.8818
227 1EB 0.8817
228 WF4 0.8815
229 UN3 0.8815
230 9JT 0.8814
231 6P3 0.8813
232 HAU 0.8808
233 NNF 0.8807
234 338 0.8805
235 A6W 0.8802
236 IDZ 0.8800
237 PIT 0.8799
238 CBE 0.8795
239 613 0.8795
240 KWD 0.8795
241 6XR 0.8794
242 FYR 0.8792
243 A05 0.8787
244 1FL 0.8783
245 XYS XYS 0.8780
246 JMM 0.8779
247 5M2 0.8778
248 JCQ 0.8777
249 Q0K 0.8777
250 BBP 0.8776
251 BUX 0.8775
252 ZUF 0.8771
253 HPZ 0.8770
254 IYX 0.8768
255 6VW 0.8768
256 69W 0.8767
257 YE7 0.8767
258 MT6 0.8764
259 1OT 0.8763
260 DTQ 0.8761
261 EBB 0.8761
262 P7V 0.8756
263 YE6 0.8755
264 J3B 0.8754
265 0SX 0.8753
266 FJR 0.8747
267 907 0.8745
268 4B8 0.8745
269 Z3R 0.8742
270 P4T 0.8742
271 334 0.8739
272 T21 0.8736
273 EQU 0.8734
274 4HG 0.8731
275 NZ4 0.8730
276 136 0.8728
277 GN5 0.8727
278 ML1 0.8726
279 FTK 0.8723
280 P34 0.8719
281 88X 0.8717
282 LWS 0.8716
283 28A 0.8714
284 7N8 0.8713
285 A8D 0.8712
286 361 0.8711
287 7KE 0.8709
288 797 0.8708
289 1FE 0.8708
290 NPZ 0.8695
291 ECS 0.8689
292 KWV 0.8689
293 LR2 0.8687
294 EST 0.8687
295 FHV 0.8686
296 LZJ 0.8686
297 BXZ 0.8683
298 ZRK 0.8681
299 GF7 0.8679
300 4AU 0.8677
301 6WU 0.8677
302 OT4 0.8677
303 57U 0.8676
304 MBE 0.8668
305 B4L 0.8665
306 17M 0.8665
307 ENY 0.8664
308 NPS 0.8661
309 ESR 0.8661
310 J1K 0.8657
311 6FG 0.8653
312 6FX 0.8653
313 J2W 0.8648
314 5OR 0.8647
315 FMH 0.8643
316 VGV 0.8642
317 J3Z 0.8641
318 ZRL 0.8633
319 0H5 0.8632
320 9C8 0.8622
321 ML2 0.8621
322 AQN 0.8617
323 3D3 0.8617
324 EV2 0.8616
325 L43 0.8613
326 7FU 0.8611
327 KVD 0.8611
328 JF5 0.8610
329 3SU 0.8605
330 ZW2 0.8600
331 ESM 0.8594
332 BU7 0.8594
333 39Z 0.8592
334 KLS 0.8585
335 PNJ 0.8583
336 HRD 0.8580
337 MR6 0.8580
338 MXM 0.8579
339 XYP XYP 0.8578
340 BER 0.8574
341 NQ7 0.8574
342 0S0 0.8568
343 SQG 0.8566
344 JTN 0.8564
345 0LA 0.8562
346 ECZ 0.8560
347 8E3 0.8558
348 ERZ 0.8555
349 8XY 0.8554
350 0XR 0.8550
351 18E 0.8550
352 CUH 0.8548
353 2WU 0.8536
354 JCZ 0.8520
355 HTK 0.8516
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4KIL; Ligand: 1R5; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4kil.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
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