Receptor
PDB id Resolution Class Description Source Keywords
4lvd 1.75 Å EC: 2.4.2.12 FRAGMENT-BASED IDENTIFICATION OF AMIDES DERIVED FROM TRANS-2 3-YL)CYCLOPROPANECARBOXYLIC ACID AS POTENT INHIBITORS OF HUN ICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) HOMO SAPIENS TRANSFERASE TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
Ref.: IDENTIFICATION OF AMIDES DERIVED FROM 1H-PYRAZOLO[3,4-B]PYRIDINE-5-CARBOXYLIC ACID AS POT INHIBITORS OF HUMAN NICOTINAMIDE PHOSPHORIBOSYLTRAN (NAMPT). BIOORG.MED.CHEM.LETT. V. 23 5488 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
1EB A:603;
B:603;
 Valid;
Valid;
 none;
none;
 submit data
206.198 C10 H10 N2 O3 c1cc(...
PO4 A:602;
B:601;
B:602;
A:601;
 Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
 submit data
94.971 O4 P [O-]P...
EDO B:604;
 Invalid;
 none;
 submit data
62.068 C2 H6 O2 C(CO)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4O12 2.5 Å EC: 2.4.2.12 STRUCTURAL AND BIOCHEMICAL ANALYSES OF THE CATALYSIS AND POT IMPACT OF INHIBITOR PHOSPHORIBOSYLATION BY HUMAN NICOTINAMIP HOSPHORIBOSYLTRANSFERASE HOMO SAPIENS TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
Ref.: STRUCTURAL AND BIOCHEMICAL ANALYSES OF THE CATALYSI POTENCY IMPACT OF INHIBITOR PHOSPHORIBOSYLATION BY NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE. CHEMBIOCHEM V. 15 1121 2014
Members (48)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4O0Z ic50 = 0.057 uM 2RM C22 H16 F2 N2 O3 S c1cc2ccc(c....
2 5KIT ic50 = 0.013 uM 6TA C21 H30 N4 O3 CC(C)(C)OC....
3 3DKJ - UNU C7 H7 N O c1ccc(cc1)....
4 4L4L - 1XC C26 H25 F2 N3 O10 P S c1cc(ccc1C....
5 2GVG - NMN C11 H16 N2 O8 P c1cc(c[n+]....
6 4LVB - 20N C12 H14 N2 O2 CC(=O)Nc1c....
7 4N9D ic50 = 0.019 uM 2HJ C23 H25 N3 O3 S CC(C)(C)c1....
8 4M6P ic50 = 0.054 uM 20R C20 H16 N4 O3 S c1ccc(cc1)....
9 4LVG - 20O C21 H18 N2 O3 S c1ccc(cc1)....
10 4O10 ic50 = 0.078 uM 2QF C22 H16 F2 N2 O3 S c1cc2cc(cc....
11 4O28 ic50 = 0.029 uM 1QS C21 H15 F2 N3 O3 S c1cc(ccc1C....
12 4LV9 - 20J C8 H7 Cl N2 O2 S CC1=Nc2ccc....
13 3DKL - PRP C5 H13 O14 P3 C([C@@H]1[....
14 4LVD - 1EB C10 H10 N2 O3 c1cc(ccc1N....
15 2H3D - NMN C11 H16 N2 O8 P c1cc(c[n+]....
16 4O1B ic50 = 0.385 uM DGB C24 H29 N3 O2 c1ccc(cc1)....
17 5NSD - 96Q C35 H29 F3 N4 O3 c1cc(ccc1c....
18 4O13 ic50 = 0.015 uM 2P1 C21 H15 F3 N4 O3 S c1cc(cc(c1....
19 4JR5 ic50 = 0.007 uM 1LS C18 H22 N4 O2 S2 c1cc(cnc1)....
20 3DGR - A12 C11 H17 N5 O9 P2 c1nc(c2c(n....
21 2E5C - PRP C5 H13 O14 P3 C([C@@H]1[....
22 4LTS ic50 = 4.4 nM LTS C21 H16 F3 N5 O3 S c1cc(cc(c1....
23 5U2N - 7TA C23 H26 N4 O2 CC(C)C(=O)....
24 4JNM ic50 = 3 nM 1LJ C19 H18 N4 O3 S c1ccc(cc1)....
25 4N9C Kd = 126 uM 2ZM C7 H5 N3 O2 c1cc2c(cc1....
26 4KFO - 1QS C21 H15 F2 N3 O3 S c1cc(ccc1C....
27 4L4M ic50 = 0.01 uM 1XD C21 H15 F2 N3 O3 S c1cc(ccc1C....
28 3DHD - NMN C11 H16 N2 O8 P c1cc(c[n+]....
29 4O12 ic50 = 0.002 uM 2QG C19 H22 Cl N5 O c1cc(ccc1O....
30 4M6Q ic50 = 0.0061 uM 20T C26 H24 F3 N4 O10 P S c1cc(cc(c1....
31 4KFN - 1QR C20 H22 N4 O3 S c1cc(ccc1C....
32 2E5D - NCA C6 H6 N2 O c1cc(cnc1)....
33 4WQ6 ic50 = 0.026 uM 3TQ C24 H29 N3 O3 S CC(C)CN1CC....
34 4O15 ic50 = 0.095 uM 2P1 C21 H15 F3 N4 O3 S c1cc(cc(c1....
35 4O1D ic50 = 0.024 uM DGB C24 H29 N3 O2 c1ccc(cc1)....
36 5UPF Ki = 2.5 nM 8HV C24 H26 F N3 O3 CC(C)(C(=O....
37 4LVF - 20P C15 H14 N2 O c1ccc(cc1)....
38 4LWW ic50 = 29 nM LWW C21 H17 N3 O3 S c1ccc(cc1)....
39 5UPE Ki = 9 nM 8HY C25 H23 N3 O2 c1ccc(cc1)....
40 3DHF - NMN C11 H16 N2 O8 P c1cc(c[n+]....
41 4LVA - 20M C22 H28 N6 O4 S2 c1cc(ccc1C....
42 4O16 - 1XC C26 H25 F2 N3 O10 P S c1cc(ccc1C....
43 6PEB ic50 = 2.7 nM OE4 C24 H20 N4 O3 c1ccc2c(c1....
44 5WI0 ic50 = 360 uM AQ1 C13 H14 F N3 O CCCC1=CC(=....
45 4N9E ic50 = 0.015 uM 2HL C26 H25 N5 O2 c1ccc(cc1)....
46 5U2M - 7T7 C21 H23 N3 O3 c1ccc2c(c1....
47 5WI1 ic50 = 10 uM AOY C12 H13 N O2 c1ccc(cc1)....
48 4KFP ic50 = 0.01 uM 1R7 C25 H30 N4 O4 S c1cc(ccc1C....
70% Homology Family (48)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4O0Z ic50 = 0.057 uM 2RM C22 H16 F2 N2 O3 S c1cc2ccc(c....
2 5KIT ic50 = 0.013 uM 6TA C21 H30 N4 O3 CC(C)(C)OC....
3 3DKJ - UNU C7 H7 N O c1ccc(cc1)....
4 4L4L - 1XC C26 H25 F2 N3 O10 P S c1cc(ccc1C....
5 2GVG - NMN C11 H16 N2 O8 P c1cc(c[n+]....
6 4LVB - 20N C12 H14 N2 O2 CC(=O)Nc1c....
7 4N9D ic50 = 0.019 uM 2HJ C23 H25 N3 O3 S CC(C)(C)c1....
8 4M6P ic50 = 0.054 uM 20R C20 H16 N4 O3 S c1ccc(cc1)....
9 4LVG - 20O C21 H18 N2 O3 S c1ccc(cc1)....
10 4O10 ic50 = 0.078 uM 2QF C22 H16 F2 N2 O3 S c1cc2cc(cc....
11 4O28 ic50 = 0.029 uM 1QS C21 H15 F2 N3 O3 S c1cc(ccc1C....
12 4LV9 - 20J C8 H7 Cl N2 O2 S CC1=Nc2ccc....
13 3DKL - PRP C5 H13 O14 P3 C([C@@H]1[....
14 4LVD - 1EB C10 H10 N2 O3 c1cc(ccc1N....
15 2H3D - NMN C11 H16 N2 O8 P c1cc(c[n+]....
16 4O1B ic50 = 0.385 uM DGB C24 H29 N3 O2 c1ccc(cc1)....
17 5NSD - 96Q C35 H29 F3 N4 O3 c1cc(ccc1c....
18 4O13 ic50 = 0.015 uM 2P1 C21 H15 F3 N4 O3 S c1cc(cc(c1....
19 4JR5 ic50 = 0.007 uM 1LS C18 H22 N4 O2 S2 c1cc(cnc1)....
20 3DGR - A12 C11 H17 N5 O9 P2 c1nc(c2c(n....
21 2E5C - PRP C5 H13 O14 P3 C([C@@H]1[....
22 4LTS ic50 = 4.4 nM LTS C21 H16 F3 N5 O3 S c1cc(cc(c1....
23 5U2N - 7TA C23 H26 N4 O2 CC(C)C(=O)....
24 4JNM ic50 = 3 nM 1LJ C19 H18 N4 O3 S c1ccc(cc1)....
25 4N9C Kd = 126 uM 2ZM C7 H5 N3 O2 c1cc2c(cc1....
26 4KFO - 1QS C21 H15 F2 N3 O3 S c1cc(ccc1C....
27 4L4M ic50 = 0.01 uM 1XD C21 H15 F2 N3 O3 S c1cc(ccc1C....
28 3DHD - NMN C11 H16 N2 O8 P c1cc(c[n+]....
29 4O12 ic50 = 0.002 uM 2QG C19 H22 Cl N5 O c1cc(ccc1O....
30 4M6Q ic50 = 0.0061 uM 20T C26 H24 F3 N4 O10 P S c1cc(cc(c1....
31 4KFN - 1QR C20 H22 N4 O3 S c1cc(ccc1C....
32 2E5D - NCA C6 H6 N2 O c1cc(cnc1)....
33 4WQ6 ic50 = 0.026 uM 3TQ C24 H29 N3 O3 S CC(C)CN1CC....
34 4O15 ic50 = 0.095 uM 2P1 C21 H15 F3 N4 O3 S c1cc(cc(c1....
35 4O1D ic50 = 0.024 uM DGB C24 H29 N3 O2 c1ccc(cc1)....
36 5UPF Ki = 2.5 nM 8HV C24 H26 F N3 O3 CC(C)(C(=O....
37 4LVF - 20P C15 H14 N2 O c1ccc(cc1)....
38 4LWW ic50 = 29 nM LWW C21 H17 N3 O3 S c1ccc(cc1)....
39 5UPE Ki = 9 nM 8HY C25 H23 N3 O2 c1ccc(cc1)....
40 3DHF - NMN C11 H16 N2 O8 P c1cc(c[n+]....
41 4LVA - 20M C22 H28 N6 O4 S2 c1cc(ccc1C....
42 4O16 - 1XC C26 H25 F2 N3 O10 P S c1cc(ccc1C....
43 6PEB ic50 = 2.7 nM OE4 C24 H20 N4 O3 c1ccc2c(c1....
44 5WI0 ic50 = 360 uM AQ1 C13 H14 F N3 O CCCC1=CC(=....
45 4N9E ic50 = 0.015 uM 2HL C26 H25 N5 O2 c1ccc(cc1)....
46 5U2M - 7T7 C21 H23 N3 O3 c1ccc2c(c1....
47 5WI1 ic50 = 10 uM AOY C12 H13 N O2 c1ccc(cc1)....
48 4KFP ic50 = 0.01 uM 1R7 C25 H30 N4 O4 S c1cc(ccc1C....
50% Homology Family (48)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4O0Z ic50 = 0.057 uM 2RM C22 H16 F2 N2 O3 S c1cc2ccc(c....
2 5KIT ic50 = 0.013 uM 6TA C21 H30 N4 O3 CC(C)(C)OC....
3 3DKJ - UNU C7 H7 N O c1ccc(cc1)....
4 4L4L - 1XC C26 H25 F2 N3 O10 P S c1cc(ccc1C....
5 2GVG - NMN C11 H16 N2 O8 P c1cc(c[n+]....
6 4LVB - 20N C12 H14 N2 O2 CC(=O)Nc1c....
7 4N9D ic50 = 0.019 uM 2HJ C23 H25 N3 O3 S CC(C)(C)c1....
8 4M6P ic50 = 0.054 uM 20R C20 H16 N4 O3 S c1ccc(cc1)....
9 4LVG - 20O C21 H18 N2 O3 S c1ccc(cc1)....
10 4O10 ic50 = 0.078 uM 2QF C22 H16 F2 N2 O3 S c1cc2cc(cc....
11 4O28 ic50 = 0.029 uM 1QS C21 H15 F2 N3 O3 S c1cc(ccc1C....
12 4LV9 - 20J C8 H7 Cl N2 O2 S CC1=Nc2ccc....
13 3DKL - PRP C5 H13 O14 P3 C([C@@H]1[....
14 4LVD - 1EB C10 H10 N2 O3 c1cc(ccc1N....
15 2H3D - NMN C11 H16 N2 O8 P c1cc(c[n+]....
16 4O1B ic50 = 0.385 uM DGB C24 H29 N3 O2 c1ccc(cc1)....
17 5NSD - 96Q C35 H29 F3 N4 O3 c1cc(ccc1c....
18 4O13 ic50 = 0.015 uM 2P1 C21 H15 F3 N4 O3 S c1cc(cc(c1....
19 4JR5 ic50 = 0.007 uM 1LS C18 H22 N4 O2 S2 c1cc(cnc1)....
20 3DGR - A12 C11 H17 N5 O9 P2 c1nc(c2c(n....
21 2E5C - PRP C5 H13 O14 P3 C([C@@H]1[....
22 4LTS ic50 = 4.4 nM LTS C21 H16 F3 N5 O3 S c1cc(cc(c1....
23 5U2N - 7TA C23 H26 N4 O2 CC(C)C(=O)....
24 4JNM ic50 = 3 nM 1LJ C19 H18 N4 O3 S c1ccc(cc1)....
25 4N9C Kd = 126 uM 2ZM C7 H5 N3 O2 c1cc2c(cc1....
26 4KFO - 1QS C21 H15 F2 N3 O3 S c1cc(ccc1C....
27 4L4M ic50 = 0.01 uM 1XD C21 H15 F2 N3 O3 S c1cc(ccc1C....
28 3DHD - NMN C11 H16 N2 O8 P c1cc(c[n+]....
29 4O12 ic50 = 0.002 uM 2QG C19 H22 Cl N5 O c1cc(ccc1O....
30 4M6Q ic50 = 0.0061 uM 20T C26 H24 F3 N4 O10 P S c1cc(cc(c1....
31 4KFN - 1QR C20 H22 N4 O3 S c1cc(ccc1C....
32 2E5D - NCA C6 H6 N2 O c1cc(cnc1)....
33 4WQ6 ic50 = 0.026 uM 3TQ C24 H29 N3 O3 S CC(C)CN1CC....
34 4O15 ic50 = 0.095 uM 2P1 C21 H15 F3 N4 O3 S c1cc(cc(c1....
35 4O1D ic50 = 0.024 uM DGB C24 H29 N3 O2 c1ccc(cc1)....
36 5UPF Ki = 2.5 nM 8HV C24 H26 F N3 O3 CC(C)(C(=O....
37 4LVF - 20P C15 H14 N2 O c1ccc(cc1)....
38 4LWW ic50 = 29 nM LWW C21 H17 N3 O3 S c1ccc(cc1)....
39 5UPE Ki = 9 nM 8HY C25 H23 N3 O2 c1ccc(cc1)....
40 3DHF - NMN C11 H16 N2 O8 P c1cc(c[n+]....
41 4LVA - 20M C22 H28 N6 O4 S2 c1cc(ccc1C....
42 4O16 - 1XC C26 H25 F2 N3 O10 P S c1cc(ccc1C....
43 6PEB ic50 = 2.7 nM OE4 C24 H20 N4 O3 c1ccc2c(c1....
44 5WI0 ic50 = 360 uM AQ1 C13 H14 F N3 O CCCC1=CC(=....
45 4N9E ic50 = 0.015 uM 2HL C26 H25 N5 O2 c1ccc(cc1)....
46 5U2M - 7T7 C21 H23 N3 O3 c1ccc2c(c1....
47 5WI1 ic50 = 10 uM AOY C12 H13 N O2 c1ccc(cc1)....
48 4KFP ic50 = 0.01 uM 1R7 C25 H30 N4 O4 S c1cc(ccc1C....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 1EB; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 1EB 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: 1EB; Similar ligands found: 413
No: Ligand Similarity coefficient
1 NY4 0.9658
2 9NB 0.9604
3 LWA 0.9595
4 LR8 0.9583
5 VC3 0.9501
6 J1K 0.9479
7 7N8 0.9447
8 S0D 0.9433
9 GJG 0.9431
10 6P3 0.9419
11 20N 0.9414
12 TID 0.9410
13 JCZ 0.9408
14 HNT 0.9378
15 6SD 0.9378
16 NFZ 0.9343
17 NDD 0.9342
18 4UM 0.9328
19 B15 0.9320
20 14N 0.9305
21 3VS 0.9294
22 4AF 0.9284
23 A5Q 0.9272
24 4FC 0.9270
25 L4K 0.9264
26 K3D 0.9254
27 OLU 0.9252
28 0UL 0.9251
29 3VQ 0.9246
30 M28 0.9243
31 LO1 0.9235
32 4I8 0.9235
33 PQM 0.9233
34 7FU 0.9225
35 4CN 0.9225
36 MKN 0.9217
37 KLS 0.9213
38 JMG 0.9204
39 IS2 0.9191
40 RSV 0.9188
41 RYV 0.9188
42 QIV 0.9180
43 1FE 0.9171
44 2J1 0.9168
45 3UF 0.9164
46 5H6 0.9157
47 8V8 0.9154
48 WA1 0.9148
49 M83 0.9144
50 AJ1 0.9143
51 3W3 0.9141
52 TEF 0.9140
53 3W6 0.9139
54 5O6 0.9139
55 N4E 0.9139
56 397 0.9135
57 JA5 0.9133
58 2JX 0.9128
59 4CF 0.9126
60 I2E 0.9123
61 JBZ 0.9114
62 5SJ 0.9114
63 TMG 0.9114
64 G1L 0.9113
65 FYR 0.9113
66 2FX 0.9107
67 EZL 0.9105
68 A98 0.9101
69 8EU 0.9100
70 PQS 0.9097
71 XCG 0.9097
72 5TT 0.9096
73 K7H 0.9095
74 RYY 0.9094
75 RCV 0.9093
76 NAL 0.9089
77 PNP 0.9088
78 G14 0.9087
79 KLE 0.9087
80 Y3L 0.9083
81 I3E 0.9083
82 G2V 0.9082
83 2PV 0.9082
84 AJG 0.9081
85 NK5 0.9081
86 363 0.9079
87 2P3 0.9078
88 M4N 0.9075
89 E3X 0.9073
90 7MW 0.9072
91 6FB 0.9071
92 FCW 0.9070
93 2PK 0.9070
94 8D6 0.9070
95 4MB 0.9067
96 A7H 0.9061
97 GB5 0.9059
98 3O5 0.9057
99 8YH 0.9053
100 PRL 0.9051
101 6N4 0.9050
102 D25 0.9045
103 5VU 0.9038
104 BIH 0.9034
105 BX4 0.9032
106 1DR 0.9030
107 833 0.9027
108 4NP 0.9024
109 A9B 0.9024
110 4ZF 0.9022
111 JAH 0.9021
112 P4T 0.9020
113 S7S 0.9019
114 27K 0.9013
115 AD6 0.9011
116 ZZA 0.9005
117 0XR 0.9005
118 109 0.9005
119 CT0 0.9004
120 EES 0.8999
121 H75 0.8995
122 ZTW 0.8994
123 B1J 0.8991
124 BQ2 0.8991
125 613 0.8990
126 D26 0.8988
127 FZM 0.8988
128 C0V 0.8987
129 7EH 0.8984
130 2QC 0.8980
131 ODK 0.8980
132 TYR 0.8976
133 LC1 0.8975
134 1A5 0.8967
135 NPS 0.8966
136 F02 0.8966
137 4BX 0.8959
138 AES 0.8957
139 5ER 0.8956
140 52F 0.8954
141 C4E 0.8953
142 YZ9 0.8952
143 HC4 0.8950
144 A6W 0.8949
145 PIQ 0.8948
146 GOE 0.8947
147 M78 0.8946
148 D9Z 0.8943
149 VFJ 0.8941
150 4HB 0.8940
151 J38 0.8937
152 5TO 0.8936
153 GHQ 0.8935
154 M25 0.8930
155 4NS 0.8930
156 7G0 0.8928
157 4FE 0.8928
158 0K7 0.8928
159 8CC 0.8923
160 GO2 0.8923
161 FHV 0.8923
162 1XS 0.8921
163 5GV 0.8910
164 S0A 0.8907
165 EZ1 0.8906
166 WV7 0.8905
167 WLH 0.8904
168 GVY 0.8903
169 ZSP 0.8903
170 H4B 0.8901
171 245 0.8901
172 1Q2 0.8901
173 P7V 0.8901
174 BC5 0.8897
175 3F4 0.8895
176 II4 0.8895
177 L2K 0.8894
178 S8P 0.8894
179 0QA 0.8892
180 72D 0.8892
181 DVK 0.8891
182 KMY 0.8888
183 1Q1 0.8888
184 RYJ 0.8885
185 NPX 0.8884
186 BGU 0.8882
187 2D2 0.8876
188 M29 0.8875
189 0OK 0.8875
190 NEU 0.8874
191 8NB 0.8874
192 F40 0.8873
193 Q8G 0.8872
194 MD6 0.8872
195 6C8 0.8870
196 657 0.8869
197 6FG 0.8866
198 K82 0.8866
199 HBI 0.8866
200 LIG 0.8861
201 0F3 0.8860
202 YE6 0.8859
203 SZ5 0.8859
204 6H2 0.8859
205 N9M 0.8859
206 VFM 0.8858
207 1HP 0.8852
208 3VX 0.8852
209 0LA 0.8852
210 4AU 0.8851
211 ZRK 0.8850
212 RZ0 0.8848
213 WG8 0.8848
214 SJK 0.8846
215 5OR 0.8846
216 P81 0.8842
217 STV 0.8841
218 TRP 0.8841
219 6DQ 0.8840
220 FT6 0.8839
221 0SY 0.8838
222 BVS 0.8837
223 HRM 0.8837
224 2L1 0.8836
225 6C9 0.8835
226 80G 0.8835
227 AP6 0.8834
228 SX2 0.8833
229 2WU 0.8832
230 20D 0.8830
231 RGK 0.8830
232 YE7 0.8829
233 9R5 0.8824
234 1OT 0.8824
235 SWX 0.8823
236 CXH 0.8821
237 2O8 0.8820
238 L15 0.8820
239 5E5 0.8820
240 0DF 0.8818
241 1R5 0.8817
242 LZ4 0.8816
243 ENO 0.8816
244 4JE 0.8812
245 T1N 0.8811
246 DFL 0.8811
247 RDV 0.8807
248 N91 0.8806
249 S60 0.8806
250 OQC 0.8805
251 A7N 0.8803
252 KWV 0.8803
253 CHQ 0.8803
254 IJ6 0.8802
255 BSU 0.8800
256 LZ5 0.8798
257 PTB 0.8795
258 VJJ 0.8795
259 F4K 0.8793
260 VFG 0.8793
261 A8D 0.8793
262 1V4 0.8788
263 6MW 0.8788
264 BIO 0.8786
265 AVX 0.8784
266 801 0.8783
267 VGS 0.8783
268 GB4 0.8783
269 L1O 0.8782
270 6KT 0.8782
271 ESJ 0.8780
272 5M2 0.8779
273 4Z1 0.8777
274 DHC 0.8777
275 L1T 0.8775
276 TJM 0.8775
277 4BF 0.8773
278 7G2 0.8772
279 K0G 0.8770
280 9FH 0.8769
281 90G 0.8769
282 ERZ 0.8768
283 S62 0.8767
284 L03 0.8762
285 EQW 0.8762
286 PH3 0.8761
287 3W8 0.8760
288 OHJ 0.8760
289 ITE 0.8760
290 JGB 0.8759
291 6C5 0.8755
292 9JT 0.8755
293 QBP 0.8754
294 NEO 0.8753
295 0OO 0.8752
296 68B 0.8750
297 WCU 0.8750
298 1V1 0.8748
299 0NJ 0.8747
300 HH6 0.8747
301 NKI 0.8746
302 EE8 0.8745
303 25F 0.8744
304 SJR 0.8743
305 C82 0.8739
306 9CE 0.8735
307 S98 0.8734
308 MR5 0.8734
309 47V 0.8732
310 BMZ 0.8731
311 122 0.8729
312 CR4 0.8729
313 7L4 0.8728
314 MGB 0.8727
315 FER 0.8724
316 IOP 0.8724
317 6C4 0.8723
318 X0U 0.8716
319 BXS 0.8716
320 108 0.8713
321 5B2 0.8712
322 LI7 0.8709
323 FMH 0.8708
324 RGP 0.8708
325 K4V 0.8708
326 A05 0.8708
327 ZHA 0.8707
328 4FF 0.8707
329 HRD 0.8706
330 4BL 0.8704
331 120 0.8703
332 FTK 0.8703
333 A73 0.8703
334 U13 0.8702
335 PQV 0.8700
336 0FR 0.8700
337 9KZ 0.8699
338 2GQ 0.8699
339 PHI 0.8693
340 NIF 0.8692
341 OJM 0.8691
342 789 0.8690
343 9BF 0.8687
344 A26 0.8686
345 7O4 0.8685
346 JF8 0.8684
347 P4L 0.8682
348 S0W 0.8681
349 121 0.8680
350 4Z0 0.8676
351 1ZC 0.8675
352 124 0.8675
353 22T 0.8673
354 Z3R 0.8671
355 D8Q 0.8668
356 0NX 0.8668
357 3D3 0.8667
358 AZM 0.8659
359 RA7 0.8650
360 SOJ 0.8646
361 GO8 0.8645
362 HPP 0.8642
363 08C 0.8639
364 FMQ 0.8639
365 27F 0.8636
366 H2B 0.8635
367 5OO 0.8634
368 ZYX 0.8633
369 IDZ 0.8632
370 RF2 0.8630
371 0MB 0.8629
372 3CX 0.8627
373 A18 0.8627
374 CFA 0.8624
375 GEN 0.8624
376 1Q4 0.8621
377 DAH 0.8619
378 HPK 0.8618
379 1V3 0.8618
380 SNV 0.8618
381 KLV 0.8613
382 EST 0.8613
383 S0E 0.8612
384 F18 0.8612
385 5RD 0.8610
386 CG 0.8610
387 4AB 0.8606
388 HHB 0.8605
389 STX 0.8605
390 5EZ 0.8597
391 ZEA 0.8597
392 A63 0.8594
393 92G 0.8593
394 LR2 0.8591
395 X6W 0.8590
396 BHS 0.8589
397 REG 0.8585
398 Q0K 0.8584
399 CBE 0.8583
400 LPA 0.8576
401 HL6 0.8572
402 HRG 0.8572
403 250 0.8571
404 ALY 0.8570
405 IBP 0.8570
406 EAE 0.8569
407 795 0.8567
408 JPQ 0.8564
409 CIU 0.8561
410 HPZ 0.8557
411 ZIP 0.8549
412 J84 0.8531
413 ZYC 0.8525
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4O12; Ligand: 2QG; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4o12.bio1) has 107 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 4O12; Ligand: 2QG; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4o12.bio1) has 126 residues
No: Leader PDB Ligand Sequence Similarity
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