Receptor
PDB id Resolution Class Description Source Keywords
4n97 1.97 Å EC: 2.7.7.7 E. COLI SLIDING CLAMP IN COMPLEX WITH 5-NITROINDOLE ESCHERICHIA COLI SLIDING CLAMP DNAN TRANSFERASE
Ref.: DISCOVERY OF LEAD COMPOUNDS TARGETING THE BACTERIAL CLAMP USING A FRAGMENT-BASED APPROACH. J.MED.CHEM. V. 57 2799 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PEG A:402;
A:403;
B:401;
A:404;
 Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
 submit data
106.12 C4 H10 O3 C(COC...
2HU A:401;
 Valid;
 none;
 submit data
162.145 C8 H6 N2 O2 c1cc2...
CA A:405;
 Part of Protein;
 none;
 submit data
40.078 Ca [Ca+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4K3P 2.15 Å EC: 2.7.7.7 E. COLI SLIDING CLAMP IN COMPLEX WITH ACQLALF ESCHERICHIA COLI E. COLI SLIDING CLAMP TRANSFERASE
Ref.: STRUCTURAL AND THERMODYNAMIC DISSECTION OF LINEAR M RECOGNITION BY THE E. COLI SLIDING CLAMP J.MED.CHEM. V. 56 8665 2013
Members (22)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 21 families.
1 4MJR Ki = 283 uM 0LA C15 H12 Cl N O2 C[C@@H](c1....
2 4N94 - 2HO C7 H5 F2 N O c1cc(c(cc1....
3 4N98 Ki = 280 uM 4FC C13 H9 F O2 c1cc(ccc1c....
4 4N95 - 2HQ C8 H4 Cl N O2 c1cc2c(cc1....
5 4MJQ Ki = 193 uM 27R C15 H12 Br N O3 c1cc(c(c(c....
6 3D1E - THR LEU MET THR GLY GLN LEU GLY LEU PHE n/a n/a
7 6FVM - ACE GLN ALC ASP LEU PHE n/a n/a
8 3D1G Ki ~ 10 uM 322 C14 H13 Br2 N O5 S2 CCOc1cc(c(....
9 4K3O Kd = 36.7 uM ACE GLN ALA ASP LEU PHE n/a n/a
10 4K3L ic50 = 1.1 mM ACE LEU PHE n/a n/a
11 4N9A Ki = 64 uM 2J2 C13 H12 Cl N O2 c1cc2c(cc1....
12 4K3K ic50 = 4.44 mM SFK C15 H21 N O3 CC(C)CCC(=....
13 3D1F - SER GLU GLN VAL GLU LEU GLU PHE ASP 323 n/a n/a
14 4K3M Kd = 281.2 uM ALA LEU ASP LEU PHE n/a n/a
15 4K3R Kd = 259.1 uM ACE GLN LEU ASP LEU ALA n/a n/a
16 4K3Q Kd = 115.1 uM ACE GLN LEU ASP ALA PHE n/a n/a
17 4K3P Kd = 1.6 uM ACE GLN LEU ALA LEU PHE n/a n/a
18 4N99 Ki = 216 uM 2J1 C13 H12 Cl N O2 c1c2c(cc(c....
19 4MJP Ki = 131 uM 27O C19 H22 O2 C[C@H](c1c....
20 6FVL - ACE GLN ALC ASP LEU PHE n/a n/a
21 4N96 - 6NI C7 H5 N3 O2 c1cc2cn[nH....
22 4N97 - 2HU C8 H6 N2 O2 c1cc2c(cc[....
70% Homology Family (23)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 20 families.
1 4MJR Ki = 283 uM 0LA C15 H12 Cl N O2 C[C@@H](c1....
2 4N94 - 2HO C7 H5 F2 N O c1cc(c(cc1....
3 4N98 Ki = 280 uM 4FC C13 H9 F O2 c1cc(ccc1c....
4 4N95 - 2HQ C8 H4 Cl N O2 c1cc2c(cc1....
5 4MJQ Ki = 193 uM 27R C15 H12 Br N O3 c1cc(c(c(c....
6 3D1E - THR LEU MET THR GLY GLN LEU GLY LEU PHE n/a n/a
7 6FVM - ACE GLN ALC ASP LEU PHE n/a n/a
8 3D1G Ki ~ 10 uM 322 C14 H13 Br2 N O5 S2 CCOc1cc(c(....
9 4K3O Kd = 36.7 uM ACE GLN ALA ASP LEU PHE n/a n/a
10 4K3L ic50 = 1.1 mM ACE LEU PHE n/a n/a
11 4N9A Ki = 64 uM 2J2 C13 H12 Cl N O2 c1cc2c(cc1....
12 4K3K ic50 = 4.44 mM SFK C15 H21 N O3 CC(C)CCC(=....
13 3D1F - SER GLU GLN VAL GLU LEU GLU PHE ASP 323 n/a n/a
14 4K3M Kd = 281.2 uM ALA LEU ASP LEU PHE n/a n/a
15 4K3R Kd = 259.1 uM ACE GLN LEU ASP LEU ALA n/a n/a
16 4K3Q Kd = 115.1 uM ACE GLN LEU ASP ALA PHE n/a n/a
17 4K3P Kd = 1.6 uM ACE GLN LEU ALA LEU PHE n/a n/a
18 4N99 Ki = 216 uM 2J1 C13 H12 Cl N O2 c1c2c(cc(c....
19 4MJP Ki = 131 uM 27O C19 H22 O2 C[C@H](c1c....
20 6FVL - ACE GLN ALC ASP LEU PHE n/a n/a
21 4N96 - 6NI C7 H5 N3 O2 c1cc2cn[nH....
22 4N97 - 2HU C8 H6 N2 O2 c1cc2c(cc[....
23 4TSZ Kd = 99 nM ACE GLN ALC ASP LEU ZCL n/a n/a
50% Homology Family (23)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 20 families.
1 4MJR Ki = 283 uM 0LA C15 H12 Cl N O2 C[C@@H](c1....
2 4N94 - 2HO C7 H5 F2 N O c1cc(c(cc1....
3 4N98 Ki = 280 uM 4FC C13 H9 F O2 c1cc(ccc1c....
4 4N95 - 2HQ C8 H4 Cl N O2 c1cc2c(cc1....
5 4MJQ Ki = 193 uM 27R C15 H12 Br N O3 c1cc(c(c(c....
6 3D1E - THR LEU MET THR GLY GLN LEU GLY LEU PHE n/a n/a
7 6FVM - ACE GLN ALC ASP LEU PHE n/a n/a
8 3D1G Ki ~ 10 uM 322 C14 H13 Br2 N O5 S2 CCOc1cc(c(....
9 4K3O Kd = 36.7 uM ACE GLN ALA ASP LEU PHE n/a n/a
10 4K3L ic50 = 1.1 mM ACE LEU PHE n/a n/a
11 4N9A Ki = 64 uM 2J2 C13 H12 Cl N O2 c1cc2c(cc1....
12 4K3K ic50 = 4.44 mM SFK C15 H21 N O3 CC(C)CCC(=....
13 3D1F - SER GLU GLN VAL GLU LEU GLU PHE ASP 323 n/a n/a
14 4K3M Kd = 281.2 uM ALA LEU ASP LEU PHE n/a n/a
15 4K3R Kd = 259.1 uM ACE GLN LEU ASP LEU ALA n/a n/a
16 4K3Q Kd = 115.1 uM ACE GLN LEU ASP ALA PHE n/a n/a
17 4K3P Kd = 1.6 uM ACE GLN LEU ALA LEU PHE n/a n/a
18 4N99 Ki = 216 uM 2J1 C13 H12 Cl N O2 c1c2c(cc(c....
19 4MJP Ki = 131 uM 27O C19 H22 O2 C[C@H](c1c....
20 6FVL - ACE GLN ALC ASP LEU PHE n/a n/a
21 4N96 - 6NI C7 H5 N3 O2 c1cc2cn[nH....
22 4N97 - 2HU C8 H6 N2 O2 c1cc2c(cc[....
23 4TSZ Kd = 99 nM ACE GLN ALC ASP LEU ZCL n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 2HU; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 2HU 1 1
2 5NI 0.446809 0.894737
Similar Ligands (3D)
Ligand no: 1; Ligand: 2HU; Similar ligands found: 1173
No: Ligand Similarity coefficient
1 6NT 1.0000
2 ABI 1.0000
3 1F1 1.0000
4 3NY 1.0000
5 6NI 1.0000
6 2ZM 1.0000
7 0HN 1.0000
8 JAW 0.9998
9 3A9 0.9992
10 0HO 0.9968
11 JDN 0.9953
12 JB8 0.9951
13 15N 0.9925
14 0JD 0.9893
15 E1T 0.9836
16 HA5 0.9787
17 5OB 0.9735
18 SLS 0.9720
19 J9Q 0.9720
20 BZ2 0.9718
21 BZ3 0.9716
22 6KT 0.9713
23 5XC 0.9694
24 M2K 0.9688
25 INO 0.9687
26 9FE 0.9678
27 9FL 0.9676
28 4WL 0.9672
29 9CA 0.9664
30 ESX 0.9663
31 1IT 0.9657
32 5RN 0.9655
33 DHB 0.9652
34 4ZA 0.9647
35 ICO 0.9647
36 NNO 0.9646
37 ICB 0.9645
38 9ZE 0.9645
39 EA1 0.9644
40 4P5 0.9641
41 8ZE 0.9625
42 PD2 0.9622
43 2HC 0.9617
44 97T 0.9613
45 FHB 0.9611
46 K97 0.9598
47 MSR 0.9595
48 8WO 0.9592
49 ANN 0.9591
50 PNZ 0.9586
51 TYL 0.9578
52 OVM 0.9573
53 2BG 0.9570
54 CHB 0.9570
55 3MB 0.9568
56 4A3 0.9568
57 4NC 0.9568
58 8XL 0.9567
59 F9Y 0.9566
60 4NB 0.9566
61 92P 0.9556
62 C2Y 0.9555
63 KYA 0.9553
64 GJP 0.9551
65 1HN 0.9549
66 P9P 0.9549
67 8G0 0.9546
68 4RU 0.9545
69 2HO 0.9544
70 CWJ 0.9542
71 HIS 0.9541
72 CH9 0.9541
73 MAJ 0.9540
74 HHI 0.9537
75 3HM 0.9535
76 93K 0.9533
77 3PF 0.9532
78 GO2 0.9532
79 PEY 0.9527
80 XX2 0.9525
81 4BZ 0.9520
82 F31 0.9519
83 XIY 0.9519
84 94W 0.9517
85 F4E 0.9516
86 2O6 0.9514
87 6TZ 0.9513
88 PDC 0.9508
89 BZJ 0.9506
90 MYJ 0.9505
91 MR1 0.9504
92 M4E 0.9503
93 ESI 0.9501
94 DNF 0.9499
95 FA0 0.9498
96 428 0.9496
97 52C 0.9493
98 PIM 0.9492
99 N2I 0.9486
100 AN3 0.9484
101 PHB 0.9483
102 COU 0.9480
103 5QY 0.9475
104 PAB 0.9473
105 6FZ 0.9472
106 4BL 0.9470
107 VNL 0.9470
108 ET2 0.9469
109 KDV 0.9468
110 SNO 0.9467
111 I3A 0.9465
112 H42 0.9463
113 9TW 0.9460
114 SNU 0.9460
115 0F9 0.9459
116 OCH 0.9455
117 8HC 0.9455
118 FBB 0.9454
119 N1E 0.9451
120 HBD 0.9451
121 4TU 0.9450
122 173 0.9450
123 0FK 0.9449
124 BHA 0.9444
125 PIY 0.9444
126 12T 0.9443
127 03V 0.9442
128 5CU 0.9442
129 4FS 0.9441
130 D48 0.9441
131 2LY 0.9439
132 5RO 0.9439
133 ES5 0.9438
134 IHB 0.9437
135 PJW 0.9436
136 JB5 0.9432
137 DOB 0.9432
138 92K 0.9431
139 QSB 0.9431
140 ODO 0.9430
141 ZYR 0.9429
142 BPN 0.9427
143 TZF 0.9422
144 2AQ 0.9420
145 1Y6 0.9416
146 K2T 0.9415
147 LQ2 0.9413
148 4I8 0.9413
149 IAC 0.9408
150 5NU 0.9407
151 OW4 0.9407
152 4M0 0.9406
153 BEA 0.9403
154 4BY 0.9403
155 NPO 0.9403
156 HQJ 0.9400
157 5VL 0.9399
158 1M2 0.9396
159 KTW 0.9394
160 4MA 0.9394
161 2FY 0.9392
162 MQN 0.9392
163 SKF 0.9391
164 AKG 0.9390
165 1A7 0.9389
166 HC4 0.9389
167 E7Z 0.9388
168 ES2 0.9384
169 BGC 0.9384
170 30G 0.9379
171 OGA 0.9377
172 27B 0.9376
173 N8Y 0.9374
174 5LA 0.9373
175 G3E 0.9372
176 GDE 0.9372
177 4FA 0.9371
178 4JQ 0.9370
179 CPZ 0.9370
180 7HQ 0.9365
181 JG8 0.9365
182 GAB 0.9364
183 TCA 0.9362
184 TT4 0.9360
185 PBZ 0.9360
186 CLW 0.9358
187 PHU 0.9358
188 HDH 0.9355
189 KJU 0.9355
190 TSS 0.9351
191 3ZB 0.9350
192 Z5P 0.9350
193 36R 0.9348
194 9R5 0.9348
195 S0E 0.9345
196 0BP 0.9345
197 4NM 0.9342
198 PPY 0.9342
199 826 0.9342
200 6RQ 0.9340
201 MS9 0.9340
202 2F6 0.9338
203 SE2 0.9337
204 4SX 0.9337
205 AA 0.9336
206 GVG 0.9333
207 VGD 0.9332
208 SKM 0.9331
209 36E 0.9330
210 BCU 0.9327
211 NID 0.9325
212 UNJ 0.9324
213 J5I 0.9323
214 M4T 0.9322
215 4Z4 0.9322
216 5MI 0.9322
217 RM1 0.9322
218 P9E 0.9319
219 0TU 0.9318
220 1P8 0.9317
221 11S 0.9315
222 BNL 0.9312
223 5MB 0.9310
224 F60 0.9310
225 JAE 0.9310
226 ANF 0.9310
227 ES9 0.9309
228 L5V 0.9309
229 YZM 0.9309
230 TTL 0.9308
231 TIU 0.9307
232 RNO 0.9304
233 TTY 0.9304
234 7W1 0.9303
235 1L5 0.9303
236 S2G 0.9303
237 3HB 0.9302
238 AOT 0.9301
239 12Q 0.9298
240 363 0.9296
241 E5X 0.9295
242 4ME 0.9293
243 4LW 0.9292
244 0N7 0.9291
245 2K4 0.9290
246 5H1 0.9288
247 14O 0.9287
248 15E 0.9286
249 6AI 0.9284
250 5QX 0.9282
251 OW7 0.9282
252 EVF 0.9282
253 717 0.9281
254 R20 0.9280
255 LT2 0.9279
256 4YO 0.9277
257 J6W 0.9277
258 DHR 0.9276
259 C1M 0.9271
260 ONR 0.9271
261 B62 0.9270
262 H4N 0.9269
263 JLZ 0.9267
264 CTL 0.9267
265 2HQ 0.9264
266 N91 0.9263
267 ISZ 0.9263
268 AC6 0.9263
269 4AA 0.9262
270 ABV 0.9262
271 A7H 0.9260
272 2HG 0.9260
273 FK1 0.9257
274 XHP 0.9256
275 5GU 0.9256
276 X0V 0.9254
277 URC 0.9253
278 LZM 0.9253
279 174 0.9252
280 IOS 0.9251
281 EN1 0.9250
282 42A 0.9248
283 A5E 0.9248
284 BZX 0.9245
285 BPY 0.9245
286 OTR 0.9244
287 XDK 0.9243
288 3ID 0.9243
289 DQU 0.9242
290 BTY 0.9242
291 IWT 0.9242
292 44W 0.9240
293 KTJ 0.9240
294 RD4 0.9239
295 DRG 0.9238
296 JA8 0.9237
297 SW7 0.9236
298 5VM 0.9236
299 KJH 0.9233
300 DNA 0.9232
301 EXD 0.9232
302 CFI 0.9232
303 3AB 0.9231
304 FHC 0.9230
305 GOJ 0.9229
306 HQD 0.9229
307 4CS 0.9228
308 86J 0.9227
309 AZ9 0.9227
310 0W1 0.9226
311 NOJ 0.9224
312 GZL 0.9222
313 H5B 0.9221
314 61M 0.9221
315 HQT 0.9219
316 2FQ 0.9218
317 A29 0.9218
318 OVV 0.9215
319 OTW 0.9214
320 WCE 0.9214
321 5WY 0.9214
322 AX7 0.9212
323 SHA 0.9210
324 2KA 0.9209
325 KUF 0.9209
326 PQK 0.9209
327 BDP 0.9209
328 1VK 0.9209
329 J9W 0.9208
330 LDP 0.9207
331 SRO 0.9206
332 4FH 0.9205
333 EKZ 0.9204
334 N2Z 0.9203
335 8GC 0.9203
336 1AL 0.9202
337 3VX 0.9201
338 3DM 0.9200
339 3AE 0.9200
340 53C 0.9200
341 4HM 0.9199
342 PH3 0.9199
343 GTQ 0.9198
344 8NY 0.9197
345 0FO 0.9197
346 L22 0.9195
347 Z82 0.9195
348 6ME 0.9195
349 4KL 0.9194
350 PBA 0.9194
351 8NX 0.9193
352 7O4 0.9192
353 NCT 0.9191
354 DHK 0.9191
355 6QF 0.9190
356 IFP 0.9189
357 GNM 0.9188
358 XAZ 0.9188
359 L99 0.9188
360 IV2 0.9187
361 8WT 0.9186
362 Q24 0.9186
363 AJY 0.9186
364 PO6 0.9186
365 THA 0.9186
366 4JT 0.9184
367 TGX 0.9183
368 VXX 0.9182
369 4HC 0.9180
370 6VD 0.9180
371 QPR 0.9177
372 MPV 0.9176
373 SAN 0.9176
374 2MI 0.9175
375 S7J 0.9174
376 AJ2 0.9174
377 3NT 0.9174
378 GUA 0.9174
379 INE 0.9173
380 2AL 0.9173
381 75K 0.9172
382 AZ8 0.9172
383 PE0 0.9172
384 FGZ 0.9171
385 X0U 0.9170
386 E7S 0.9170
387 MEW 0.9169
388 R8S 0.9169
389 AEF 0.9169
390 4MU 0.9167
391 259 0.9166
392 ESP 0.9166
393 BK9 0.9165
394 DMD 0.9165
395 M5K 0.9165
396 M6N 0.9164
397 5HN 0.9164
398 KOJ 0.9164
399 OVP 0.9163
400 NDH 0.9160
401 TPA 0.9159
402 AQO 0.9158
403 5JQ 0.9158
404 EUG 0.9158
405 GLC 0.9156
406 CKA 0.9155
407 1P7 0.9155
408 QSH 0.9155
409 5WV 0.9154
410 XQG 0.9151
411 L14 0.9150
412 M1Q 0.9150
413 DIN 0.9149
414 36Y 0.9147
415 YRL 0.9146
416 PAC 0.9146
417 M4S 0.9146
418 270 0.9145
419 7MU 0.9143
420 3F0 0.9143
421 BHO 0.9143
422 SKA 0.9143
423 069 0.9140
424 NIZ 0.9139
425 5XB 0.9139
426 DE5 0.9138
427 K34 0.9138
428 FP1 0.9138
429 CWS 0.9137
430 GTR 0.9136
431 GLN 0.9136
432 FYU 0.9135
433 DBH 0.9132
434 I1E 0.9131
435 URO 0.9131
436 I3E 0.9131
437 NMJ 0.9130
438 HX4 0.9129
439 XQ0 0.9128
440 EUE 0.9127
441 8TX 0.9127
442 Q6T 0.9127
443 V1T 0.9127
444 7ZE 0.9126
445 4V2 0.9126
446 MLT 0.9126
447 9AP 0.9124
448 PH2 0.9124
449 M1A 0.9123
450 5RG 0.9123
451 3OC 0.9123
452 39O 0.9122
453 AHN 0.9121
454 Q02 0.9121
455 5B1 0.9118
456 44V 0.9117
457 XIZ 0.9117
458 TSR 0.9116
459 A7W 0.9114
460 MVN 0.9112
461 AZG 0.9111
462 P92 0.9109
463 3HA 0.9109
464 HHS 0.9107
465 8CM 0.9106
466 YH7 0.9105
467 ANC 0.9103
468 7NI 0.9103
469 A2F 0.9103
470 LR5 0.9102
471 HBA 0.9102
472 FDR 0.9101
473 QBK 0.9101
474 8H8 0.9101
475 XAN 0.9100
476 GWM 0.9099
477 42C 0.9099
478 X48 0.9099
479 LDR 0.9098
480 3R4 0.9098
481 B55 0.9097
482 4XR 0.9097
483 DNC 0.9096
484 NVU 0.9096
485 FBF 0.9095
486 67N 0.9094
487 MUA 0.9094
488 XM0 0.9094
489 AY4 0.9093
490 GUN 0.9092
491 MRW 0.9091
492 9DG 0.9091
493 0P6 0.9091
494 BIK 0.9090
495 54G 0.9090
496 BRT 0.9090
497 8OZ 0.9090
498 SYV 0.9087
499 FUD 0.9087
500 7WR 0.9085
501 J9N 0.9084
502 GCU 0.9083
503 P72 0.9082
504 5TY 0.9082
505 15L 0.9081
506 F12 0.9081
507 IPB 0.9080
508 FCR 0.9079
509 HMH 0.9079
510 7VP 0.9077
511 5M0 0.9076
512 FE DB1 0.9076
513 LNR 0.9075
514 J9T 0.9075
515 5GT 0.9074
516 QX4 0.9074
517 AMH 0.9073
518 M6Z 0.9073
519 3BZ 0.9072
520 QWN 0.9071
521 4JC 0.9070
522 PXL 0.9070
523 2K8 0.9068
524 7VS 0.9067
525 1WC 0.9067
526 1XM 0.9065
527 0GZ 0.9064
528 4J8 0.9061
529 261 0.9061
530 PRZ 0.9061
531 2A9 0.9060
532 ISN 0.9060
533 2ZQ 0.9058
534 3M0 0.9057
535 6AP 0.9056
536 344 0.9055
537 JP2 0.9055
538 BOA 0.9052
539 GF4 0.9051
540 OAA 0.9051
541 LEL 0.9050
542 6GU 0.9050
543 TSU 0.9050
544 V55 0.9050
545 3J8 0.9048
546 6FB 0.9048
547 JBK 0.9048
548 AZM 0.9047
549 FF2 0.9045
550 QXW 0.9043
551 141 0.9042
552 M1E 0.9041
553 AZA 0.9038
554 KMH 0.9038
555 NQ 0.9037
556 B57 0.9037
557 DX4 0.9037
558 FBM 0.9037
559 RXA 0.9035
560 KKN 0.9034
561 OQC 0.9034
562 SN4 0.9033
563 DHY 0.9033
564 AL0 0.9033
565 UAN 0.9032
566 FDB 0.9032
567 3QV 0.9032
568 9TZ 0.9032
569 TMG 0.9032
570 SAL 0.9030
571 TH7 0.9030
572 NAG 0.9030
573 9UL 0.9030
574 MD6 0.9028
575 AHR 0.9027
576 HLD 0.9026
577 DYA 0.9026
578 JND 0.9026
579 ES7 0.9025
580 F9P 0.9025
581 BQ2 0.9024
582 68A 0.9024
583 BP7 0.9024
584 HMU 0.9021
585 GZ2 0.9020
586 VK3 0.9018
587 Q88 0.9017
588 M45 0.9017
589 EYV 0.9017
590 7MW 0.9015
591 PHE 0.9015
592 2QC 0.9013
593 2BX 0.9013
594 AJV 0.9012
595 7W4 0.9012
596 UFV 0.9011
597 TWO 0.9010
598 BE2 0.9009
599 M0W 0.9009
600 BSX 0.9007
601 7MX 0.9006
602 2AK 0.9004
603 R2P 0.9004
604 2D0 0.9003
605 PRF 0.9003
606 TOF 0.9002
607 4VP 0.8999
608 AMS 0.8999
609 BZE 0.8998
610 8NB 0.8997
611 LMR 0.8996
612 HHR 0.8995
613 IGA 0.8993
614 M5H 0.8993
615 5JL 0.8992
616 6CS 0.8992
617 DPT 0.8990
618 HHA 0.8990
619 4SV 0.8990
620 NDG 0.8989
621 EWG 0.8988
622 FAN 0.8987
623 28N 0.8987
624 6M9 0.8986
625 BCP 0.8985
626 GLU 0.8985
627 CIT 0.8984
628 M0Q 0.8984
629 PZM 0.8984
630 AKH 0.8983
631 TYR 0.8983
632 4NZ 0.8982
633 8W9 0.8980
634 FBS 0.8979
635 0FN 0.8978
636 H8N 0.8976
637 XCG 0.8975
638 R9Y 0.8975
639 PYQ 0.8974
640 0CU 0.8974
641 XRG 0.8973
642 PEA 0.8973
643 4XV 0.8972
644 OMD 0.8972
645 1QP 0.8971
646 M78 0.8971
647 HCI 0.8970
648 BPU 0.8969
649 ES0 0.8969
650 ZZT 0.8968
651 5MK 0.8967
652 GCS 0.8967
653 CLZ 0.8965
654 1KP 0.8961
655 DHS 0.8960
656 AAS 0.8959
657 X8D 0.8957
658 CWM 0.8957
659 PQ0 0.8957
660 CK2 0.8957
661 KMY 0.8955
662 3R6 0.8954
663 JTH 0.8954
664 54X 0.8954
665 RAT 0.8952
666 45L 0.8952
667 PZI 0.8952
668 9KT 0.8951
669 GV9 0.8951
670 APS 0.8951
671 GYE 0.8950
672 MWP 0.8948
673 SX1 0.8946
674 APG 0.8946
675 HH5 0.8945
676 C82 0.8944
677 OK7 0.8944
678 209 0.8944
679 N3W 0.8942
680 DRL 0.8942
681 DEW 0.8940
682 CSN 0.8940
683 G3F 0.8940
684 HLZ 0.8939
685 6DP 0.8938
686 M1H 0.8936
687 BEZ 0.8935
688 N2M 0.8933
689 3FH 0.8932
690 NSP 0.8930
691 JKE 0.8930
692 LL1 0.8929
693 APZ 0.8928
694 8MO 0.8926
695 HPS 0.8925
696 NPY 0.8924
697 268 0.8923
698 QIC 0.8922
699 SYA 0.8922
700 1Z6 0.8921
701 FA1 0.8921
702 P7Y 0.8920
703 2EC 0.8920
704 3IT 0.8920
705 RMN 0.8920
706 EVA 0.8920
707 290 0.8919
708 2FX 0.8919
709 8IG 0.8918
710 QUZ 0.8918
711 FK8 0.8917
712 4JM 0.8916
713 CFP 0.8914
714 SG2 0.8913
715 LI6 0.8913
716 FLC 0.8913
717 G5V 0.8912
718 KT7 0.8912
719 K5W 0.8912
720 TYE 0.8911
721 6BL 0.8911
722 FQI 0.8911
723 GAL 0.8911
724 M3H 0.8911
725 51R 0.8910
726 1DW 0.8910
727 ASO 0.8910
728 37T 0.8910
729 BNF 0.8910
730 ES6 0.8908
731 S24 0.8906
732 NCA 0.8906
733 8S0 0.8906
734 ARP 0.8905
735 KTA 0.8904
736 KBB 0.8903
737 W81 0.8903
738 3U4 0.8902
739 GXY 0.8902
740 LZ2 0.8899
741 DBX 0.8899
742 3Z8 0.8898
743 5NS 0.8897
744 F0J 0.8897
745 DA4 0.8897
746 QMS 0.8896
747 82I 0.8895
748 SSC 0.8894
749 23A 0.8894
750 XXP 0.8892
751 5F5 0.8891
752 463 0.8891
753 0RW 0.8889
754 MZM 0.8889
755 ADA 0.8888
756 UFO 0.8888
757 ZEC 0.8887
758 9MG 0.8887
759 HSO 0.8887
760 KBZ 0.8887
761 AX3 0.8885
762 X11 0.8884
763 3HG 0.8883
764 Y3L 0.8882
765 NLA 0.8882
766 SOE 0.8880
767 2FT 0.8879
768 CXF 0.8879
769 152 0.8879
770 ASC 0.8878
771 QWW 0.8878
772 R8V 0.8878
773 KIB 0.8877
774 0XT 0.8876
775 14J 0.8875
776 23J 0.8874
777 GCO 0.8874
778 42J 0.8873
779 JBE 0.8873
780 AES 0.8873
781 FBW 0.8872
782 4XS 0.8871
783 ORO 0.8871
784 PKU 0.8871
785 PFL 0.8871
786 BEN 0.8871
787 MO8 0.8869
788 DGJ 0.8867
789 N4E 0.8867
790 G12 0.8863
791 34D 0.8862
792 56D 0.8862
793 JRB 0.8859
794 C9E 0.8858
795 DEE 0.8858
796 B85 0.8857
797 HX3 0.8856
798 GAF 0.8856
799 EYK 0.8855
800 DDU 0.8855
801 MNP 0.8855
802 3W8 0.8853
803 QIV 0.8853
804 5NE 0.8853
805 M1Z 0.8852
806 FQX 0.8852
807 GVY 0.8852
808 AC0 0.8851
809 ZME 0.8851
810 3QM 0.8850
811 4VY 0.8850
812 2FG 0.8850
813 HNT 0.8849
814 AM4 0.8848
815 4M4 0.8847
816 F05 0.8847
817 PRA 0.8847
818 CXH 0.8846
819 XX3 0.8846
820 24B 0.8846
821 VM1 0.8845
822 ENO 0.8844
823 FOT 0.8843
824 B60 0.8842
825 JF2 0.8841
826 PBC 0.8841
827 OHP 0.8841
828 GO8 0.8840
829 F4K 0.8840
830 CN0 0.8839
831 ZXD 0.8839
832 4CM 0.8839
833 6PC 0.8839
834 MQB 0.8839
835 N5J 0.8837
836 1SQ 0.8837
837 7ME 0.8835
838 AW5 0.8833
839 DHI 0.8833
840 1LQ 0.8830
841 RSO 0.8830
842 3BU 0.8827
843 BAM 0.8827
844 OXC 0.8826
845 P3K 0.8826
846 YPN 0.8825
847 ROI 0.8824
848 QX2 0.8824
849 CFA 0.8824
850 HBO 0.8823
851 SRT 0.8822
852 9BF 0.8822
853 GGL 0.8820
854 JF1 0.8820
855 GCB 0.8819
856 XBT 0.8819
857 LGC 0.8818
858 B53 0.8817
859 NIO 0.8817
860 AMR 0.8816
861 3SL 0.8816
862 091 0.8815
863 H33 0.8815
864 4ZC 0.8814
865 ZBT 0.8814
866 5SG 0.8813
867 9EW 0.8813
868 3XX 0.8812
869 D3G 0.8811
870 OKG 0.8811
871 2LP 0.8808
872 B56 0.8808
873 Q71 0.8806
874 5IQ 0.8805
875 JBH 0.8805
876 1NP 0.8805
877 SOR 0.8805
878 UNC 0.8804
879 ES1 0.8804
880 KJY 0.8803
881 QMP 0.8802
882 505 0.8800
883 NF3 0.8800
884 MET 0.8799
885 XXG 0.8798
886 Z13 0.8798
887 2H5 0.8798
888 2JK 0.8797
889 1XA 0.8797
890 MAQ 0.8796
891 GLA 0.8796
892 D1X 0.8795
893 3VS 0.8795
894 N0Z 0.8793
895 A7N 0.8792
896 795 0.8792
897 4YS 0.8790
898 NTN 0.8790
899 DGN 0.8789
900 DHC 0.8789
901 4LV 0.8788
902 149 0.8788
903 JFJ 0.8788
904 DX3 0.8787
905 7I2 0.8786
906 OTD 0.8786
907 D07 0.8785
908 JPZ 0.8784
909 3HP 0.8784
910 5Q0 0.8780
911 SHI 0.8779
912 0LH 0.8779
913 FBA 0.8778
914 CTS 0.8777
915 DK1 0.8776
916 GIV 0.8776
917 HHH 0.8774
918 3PG 0.8774
919 8U3 0.8774
920 3VQ 0.8774
921 6R8 0.8773
922 DZA 0.8771
923 DOR 0.8771
924 3AL 0.8769
925 24W 0.8769
926 UNU 0.8768
927 6M4 0.8767
928 P81 0.8766
929 SMN 0.8765
930 IFL 0.8765
931 41K 0.8765
932 657 0.8764
933 RKV 0.8763
934 7B3 0.8761
935 0R0 0.8761
936 2CK 0.8760
937 HJP 0.8760
938 GJZ 0.8760
939 SME 0.8759
940 O2A 0.8757
941 49O 0.8757
942 SEP 0.8757
943 4NS 0.8757
944 RHU 0.8757
945 HA7 0.8756
946 258 0.8754
947 HLR 0.8753
948 EV0 0.8752
949 LPK 0.8752
950 XCZ 0.8750
951 CFF 0.8749
952 P80 0.8747
953 IF7 0.8747
954 HJ7 0.8746
955 DBJ 0.8745
956 IJZ 0.8745
957 HQY 0.8743
958 36M 0.8743
959 7B4 0.8742
960 7WV 0.8741
961 9RW 0.8740
962 NFM 0.8740
963 FB1 0.8740
964 H4E 0.8739
965 SVN 0.8738
966 9NB 0.8738
967 0NX 0.8737
968 4XF 0.8735
969 S60 0.8733
970 KW8 0.8733
971 C2B 0.8732
972 RUY 0.8731
973 ZZA 0.8730
974 GXL 0.8730
975 FBV 0.8729
976 SS1 0.8729
977 YTX 0.8728
978 M3E 0.8727
979 VGL 0.8727
980 X6X 0.8726
981 NCD 0.8725
982 2GQ 0.8723
983 MHK 0.8721
984 IQ5 0.8720
985 OA3 0.8720
986 4NP 0.8720
987 HKD 0.8718
988 SR1 0.8718
989 R1P 0.8717
990 NLE 0.8715
991 NPA 0.8714
992 TZM 0.8714
993 1P3 0.8713
994 4JL 0.8713
995 E4P 0.8712
996 ASP 0.8712
997 G2F 0.8711
998 ALE 0.8710
999 86L 0.8710
1000 DGL 0.8709
1001 XDE 0.8709
1002 F2W 0.8709
1003 CXP 0.8709
1004 5OO 0.8707
1005 PPT 0.8706
1006 EV2 0.8706
1007 K4V 0.8705
1008 K82 0.8705
1009 GRE 0.8703
1010 DPN 0.8703
1011 C2U 0.8702
1012 I2E 0.8702
1013 SD4 0.8701
1014 HFA 0.8699
1015 1WD 0.8698
1016 ODK 0.8698
1017 EMZ 0.8698
1018 7WG 0.8697
1019 TIY 0.8697
1020 PEP 0.8697
1021 FRU 0.8697
1022 ADZ 0.8696
1023 GIF 0.8696
1024 1SA 0.8695
1025 SHG 0.8692
1026 NBZ 0.8691
1027 DIE 0.8690
1028 G4D 0.8690
1029 88L 0.8689
1030 RB5 0.8689
1031 JBZ 0.8688
1032 92G 0.8687
1033 TXW 0.8686
1034 S2P 0.8685
1035 PZA 0.8685
1036 EGR 0.8684
1037 4MB 0.8683
1038 PUE 0.8683
1039 TRP 0.8679
1040 8XQ 0.8678
1041 HRM 0.8675
1042 TEP 0.8674
1043 L7T 0.8674
1044 20J 0.8674
1045 F69 0.8673
1046 HDL 0.8672
1047 F1A 0.8672
1048 3SK 0.8672
1049 LYL 0.8671
1050 X09 0.8670
1051 7N0 0.8670
1052 A13 0.8670
1053 FLV 0.8669
1054 226 0.8669
1055 B1J 0.8669
1056 HQ9 0.8667
1057 4AV 0.8666
1058 78Y 0.8665
1059 ITE 0.8663
1060 LT8 0.8662
1061 QUS 0.8661
1062 O72 0.8661
1063 MAH 0.8660
1064 H7Y 0.8660
1065 VNJ 0.8660
1066 S76 0.8659
1067 KGK 0.8658
1068 67X 0.8658
1069 6M1 0.8657
1070 QY9 0.8657
1071 4XH 0.8656
1072 MXD 0.8655
1073 BGU 0.8654
1074 PRL 0.8654
1075 5GV 0.8654
1076 AAN 0.8653
1077 BA5 0.8653
1078 NYL 0.8652
1079 HH8 0.8652
1080 JR2 0.8652
1081 8GK 0.8652
1082 QQQ 0.8651
1083 1LM 0.8648
1084 HNQ 0.8648
1085 0W8 0.8648
1086 FIX 0.8647
1087 4HB 0.8646
1088 549 0.8645
1089 JU2 0.8644
1090 TAG 0.8644
1091 5WX 0.8644
1092 5JC 0.8643
1093 HG3 0.8642
1094 1DV 0.8642
1095 SJ5 0.8642
1096 AEH 0.8641
1097 TH0 0.8641
1098 GZ3 0.8641
1099 JBQ 0.8640
1100 RBL 0.8640
1101 PHH 0.8639
1102 9SE 0.8639
1103 32X 0.8638
1104 4HP 0.8638
1105 X05 0.8637
1106 680 0.8634
1107 WOO 0.8634
1108 K32 0.8633
1109 7MK 0.8633
1110 JF6 0.8631
1111 PRY 0.8630
1112 LAO 0.8630
1113 1GN 0.8628
1114 NDM 0.8627
1115 QBM 0.8627
1116 46P 0.8625
1117 PXM 0.8625
1118 449 0.8624
1119 1X4 0.8622
1120 TBS 0.8622
1121 X0W 0.8621
1122 3DO 0.8621
1123 AEG 0.8620
1124 NOY 0.8618
1125 B5D 0.8617
1126 DIU 0.8616
1127 E1K 0.8616
1128 XYL 0.8615
1129 UEG 0.8614
1130 FDK 0.8611
1131 KYN 0.8611
1132 JZ3 0.8607
1133 H62 0.8606
1134 ICT 0.8604
1135 FBU 0.8603
1136 MCT 0.8602
1137 OA1 0.8601
1138 4P0 0.8599
1139 AGK 0.8599
1140 GLO 0.8598
1141 NFA 0.8596
1142 ZZ8 0.8590
1143 ABF 0.8589
1144 RNS 0.8586
1145 492 0.8583
1146 M6W 0.8582
1147 ORN 0.8580
1148 4HO 0.8580
1149 COI 0.8579
1150 6F0 0.8577
1151 XLS 0.8575
1152 MAN 0.8575
1153 DAL DAL 0.8574
1154 4CL 0.8574
1155 M2H 0.8570
1156 IL5 0.8569
1157 FH2 0.8566
1158 K17 0.8566
1159 ALA ALA 0.8561
1160 K25 0.8560
1161 MZG 0.8560
1162 MNM 0.8556
1163 MWJ 0.8553
1164 URS 0.8552
1165 XBZ 0.8551
1166 MPK 0.8550
1167 4JJ 0.8548
1168 FZM 0.8538
1169 R67 0.8531
1170 0OC 0.8529
1171 12B 0.8514
1172 3WA 0.8514
1173 537 0.8504
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4K3P; Ligand: ACE GLN LEU ALA LEU PHE; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4k3p.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
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