Receptor
PDB id Resolution Class Description Source Keywords
4ntm 2.05 Å EC: 4.1.2.50 QUED SOAKED WITH SEPIAPTERIN (SELENOMETHIONINE SUBSTITUTED P ESCHERICHIA COLI T-FOLD 6-PTPS QUEUOSINE BIOSYNTHESIS ENZYME SEPIAPTERIN
Ref.: BIOCHEMICAL AND STRUCTURAL STUDIES OF 6-CARBOXY-5,6,7,8-TETRAHYDROPTERIN SYNTHASE REVEAL MOLECULAR BASIS OF CATALYTIC PROMISCUITY WITHIN THE TUNNEL-FOLD SUPERFAMILY. J.BIOL.CHEM. V. 289 23641 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ZN C:201;
B:201;
D:201;
A:201;
F:201;
E:201;
 Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
 none;
none;
none;
none;
none;
none;
 submit data
65.409 Zn [Zn+2...
2K8 E:202;
F:202;
A:202;
C:202;
B:202;
D:202;
 Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
 none;
none;
none;
none;
none;
none;
 submit data
211.178 C7 H9 N5 O3 C1[C@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4NTM 2.05 Å EC: 4.1.2.50 QUED SOAKED WITH SEPIAPTERIN (SELENOMETHIONINE SUBSTITUTED P ESCHERICHIA COLI T-FOLD 6-PTPS QUEUOSINE BIOSYNTHESIS ENZYME SEPIAPTERIN
Ref.: BIOCHEMICAL AND STRUCTURAL STUDIES OF 6-CARBOXY-5,6,7,8-TETRAHYDROPTERIN SYNTHASE REVEAL MOLECULAR BASIS OF CATALYTIC PROMISCUITY WITHIN THE TUNNEL-FOLD SUPERFAMILY. J.BIOL.CHEM. V. 289 23641 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4NTM - 2K8 C7 H9 N5 O3 C1[C@@H](N....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4NTM - 2K8 C7 H9 N5 O3 C1[C@@H](N....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4NTM - 2K8 C7 H9 N5 O3 C1[C@@H](N....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 2K8; Similar ligands found: 6
No: Ligand ECFP6 Tc MDL keys Tc
1 2K8 1 1
2 44V 0.54717 0.85
3 B62 0.54717 0.85
4 H4B 0.534483 0.903226
5 BHS 0.534483 0.903226
6 ZZZ 0.527273 0.913793
Similar Ligands (3D)
Ligand no: 1; Ligand: 2K8; Similar ligands found: 1093
No: Ligand Similarity coefficient
1 HHS 1.0000
2 PH2 0.9897
3 HHR 0.9885
4 8HC 0.9883
5 B56 0.9879
6 0FK 0.9878
7 N0Z 0.9775
8 FDR 0.9764
9 V1T 0.9693
10 5TY 0.9686
11 344 0.9666
12 ZYR 0.9653
13 N8Y 0.9650
14 68A 0.9619
15 4KL 0.9595
16 3VX 0.9580
17 B21 0.9574
18 N91 0.9573
19 ZSP 0.9570
20 8NX 0.9554
21 1SS 0.9554
22 DQU 0.9549
23 OTW 0.9519
24 12T 0.9518
25 E1T 0.9515
26 HBI 0.9508
27 H2B 0.9508
28 XHP 0.9504
29 ST2 0.9502
30 MVN 0.9500
31 0FO 0.9499
32 44W 0.9498
33 15N 0.9494
34 QX4 0.9489
35 2KA 0.9485
36 6ME 0.9482
37 5RO 0.9481
38 6KT 0.9478
39 4AB 0.9477
40 PRF 0.9475
41 4RU 0.9475
42 SLS 0.9472
43 6QF 0.9471
44 1HN 0.9468
45 FCD 0.9463
46 537 0.9457
47 GJP 0.9453
48 7AP 0.9441
49 DNA 0.9441
50 CEG 0.9432
51 APS 0.9424
52 HNT 0.9420
53 KTW 0.9414
54 CLZ 0.9405
55 JF2 0.9405
56 BGU 0.9401
57 ANC 0.9399
58 61M 0.9399
59 4BY 0.9397
60 ARP 0.9397
61 JBZ 0.9395
62 ZHA 0.9391
63 BIO 0.9390
64 ESI 0.9389
65 H5B 0.9388
66 2FQ 0.9387
67 S60 0.9385
68 3J8 0.9385
69 9R5 0.9384
70 GHM 0.9382
71 0JD 0.9382
72 6FB 0.9381
73 WSD 0.9377
74 QIV 0.9370
75 UNJ 0.9367
76 CK2 0.9366
77 Y3L 0.9365
78 0J5 0.9365
79 K97 0.9363
80 BEA 0.9360
81 46M 0.9357
82 3QV 0.9353
83 ANF 0.9351
84 MD6 0.9349
85 AA 0.9349
86 EE8 0.9349
87 4JQ 0.9346
88 BPY 0.9344
89 UFO 0.9344
90 BZJ 0.9343
91 3ZB 0.9341
92 JG8 0.9339
93 MQN 0.9329
94 0TU 0.9329
95 SG2 0.9327
96 JF1 0.9323
97 THA 0.9321
98 DRG 0.9320
99 4YO 0.9302
100 363 0.9301
101 1IT 0.9301
102 AN3 0.9300
103 4BL 0.9299
104 DNF 0.9299
105 KDV 0.9294
106 9ZE 0.9291
107 HA5 0.9291
108 AJV 0.9289
109 9CA 0.9288
110 DPT 0.9282
111 E1K 0.9281
112 HBO 0.9276
113 3Y7 0.9275
114 KYA 0.9275
115 N1E 0.9275
116 JXZ 0.9275
117 FF2 0.9273
118 X0U 0.9273
119 94W 0.9267
120 C9E 0.9265
121 9FE 0.9264
122 GO2 0.9263
123 9FL 0.9262
124 FQX 0.9260
125 BPU 0.9252
126 ZEC 0.9249
127 8ZE 0.9248
128 KUF 0.9248
129 8WT 0.9247
130 8NB 0.9247
131 1QV 0.9245
132 AMR 0.9240
133 0FR 0.9240
134 JXW 0.9237
135 WS7 0.9237
136 27B 0.9235
137 1QP 0.9230
138 A7H 0.9228
139 KF5 0.9228
140 JP2 0.9227
141 0HO 0.9227
142 GSY 0.9226
143 WS6 0.9225
144 1F1 0.9224
145 3R4 0.9224
146 2HQ 0.9221
147 8MO 0.9220
148 ESX 0.9215
149 PEY 0.9215
150 JYT 0.9214
151 549 0.9213
152 N2M 0.9211
153 SKF 0.9210
154 0J4 0.9208
155 ONZ 0.9208
156 2LY 0.9206
157 J6W 0.9206
158 CWS 0.9204
159 ZYQ 0.9203
160 1KP 0.9198
161 2O6 0.9198
162 GNM 0.9195
163 S24 0.9195
164 5NE 0.9194
165 TGX 0.9192
166 LZ2 0.9190
167 20J 0.9190
168 Q71 0.9189
169 F5C 0.9189
170 8W9 0.9188
171 GO8 0.9187
172 B5D 0.9186
173 MNS 0.9184
174 92P 0.9181
175 ESP 0.9180
176 5OO 0.9180
177 86J 0.9178
178 NVU 0.9176
179 MS0 0.9174
180 PQ0 0.9173
181 7I2 0.9172
182 NAG 0.9171
183 5NS 0.9171
184 6NT 0.9170
185 N2I 0.9167
186 S0E 0.9164
187 JAW 0.9164
188 3Z8 0.9163
189 6NI 0.9162
190 0P6 0.9161
191 L22 0.9161
192 Q77 0.9160
193 IAC 0.9160
194 TSR 0.9160
195 8CM 0.9157
196 CWJ 0.9156
197 M78 0.9155
198 2GQ 0.9154
199 3NY 0.9153
200 EUE 0.9152
201 BQ2 0.9151
202 TT4 0.9147
203 C2Y 0.9146
204 MQB 0.9144
205 7PJ 0.9141
206 EXD 0.9140
207 A5E 0.9139
208 NDD 0.9139
209 428 0.9138
210 A29 0.9138
211 BZ2 0.9137
212 0HN 0.9137
213 M4E 0.9135
214 MOK 0.9135
215 GDL 0.9134
216 AJY 0.9133
217 JXK 0.9131
218 JB8 0.9129
219 JDN 0.9129
220 5WU 0.9129
221 B61 0.9129
222 LTT 0.9128
223 OQC 0.9128
224 QBK 0.9127
225 15E 0.9127
226 3A9 0.9127
227 AP4 0.9125
228 8XL 0.9124
229 AC2 0.9122
230 ICB 0.9122
231 VXX 0.9120
232 GZ2 0.9119
233 ABI 0.9117
234 5GV 0.9113
235 HJH 0.9111
236 EV3 0.9110
237 CFA 0.9109
238 TTY 0.9108
239 F52 0.9108
240 5LA 0.9108
241 BHQ 0.9107
242 KW8 0.9107
243 4TU 0.9105
244 X48 0.9104
245 N7I 0.9104
246 PHE 0.9104
247 5VU 0.9102
248 APZ 0.9101
249 TWO 0.9099
250 DX3 0.9097
251 ICO 0.9097
252 BA5 0.9096
253 57O 0.9096
254 5NI 0.9094
255 XCG 0.9094
256 JTA 0.9093
257 L21 0.9092
258 4I8 0.9091
259 2WU 0.9091
260 PMP 0.9091
261 X11 0.9090
262 CC5 0.9089
263 ALE 0.9088
264 HA7 0.9087
265 XAZ 0.9086
266 9BF 0.9086
267 E35 0.9083
268 NEO 0.9081
269 JVN 0.9081
270 GF4 0.9079
271 2FX 0.9075
272 2HC 0.9074
273 4V2 0.9074
274 2ZM 0.9074
275 IL5 0.9073
276 X04 0.9073
277 1SV 0.9073
278 1A7 0.9072
279 NEU 0.9071
280 CH9 0.9071
281 LDR 0.9070
282 G12 0.9069
283 BIK 0.9069
284 2HU 0.9068
285 28N 0.9066
286 GNV 0.9064
287 9AP 0.9063
288 K25 0.9062
289 30G 0.9062
290 KP2 0.9061
291 MSR 0.9061
292 RSV 0.9060
293 1ZC 0.9060
294 2JK 0.9060
295 CKA 0.9060
296 EGR 0.9059
297 MPU 0.9059
298 97T 0.9057
299 QUS 0.9057
300 LOG 0.9055
301 878 0.9054
302 MUA 0.9051
303 MP5 0.9049
304 TIY 0.9048
305 S98 0.9048
306 EYV 0.9046
307 0W1 0.9046
308 INE 0.9046
309 BK9 0.9045
310 BNX 0.9043
311 IBM 0.9043
312 ST1 0.9043
313 657 0.9042
314 SJK 0.9040
315 YE6 0.9039
316 IV2 0.9039
317 SNU 0.9038
318 HRM 0.9038
319 FBB 0.9038
320 PJW 0.9038
321 OCZ 0.9038
322 PRL 0.9037
323 54X 0.9036
324 CHQ 0.9035
325 IOS 0.9035
326 3N1 0.9034
327 22L 0.9030
328 ST3 0.9029
329 H33 0.9028
330 X0T 0.9027
331 2BG 0.9026
332 MAJ 0.9026
333 CXH 0.9025
334 209 0.9024
335 0N7 0.9024
336 EOL 0.9023
337 5WT 0.9022
338 MPK 0.9021
339 TSS 0.9021
340 DK1 0.9020
341 ZZA 0.9020
342 8WO 0.9019
343 5GT 0.9017
344 ENO 0.9017
345 2AK 0.9013
346 8Y7 0.9013
347 ITE 0.9013
348 CX6 0.9013
349 TMG 0.9013
350 NDG 0.9013
351 AJG 0.9012
352 NPA 0.9010
353 PPY 0.9010
354 2QC 0.9009
355 F2W 0.9007
356 ROI 0.9006
357 39O 0.9006
358 21D 0.9005
359 NGA 0.9005
360 K44 0.9005
361 A2G 0.9005
362 3VQ 0.9005
363 EVF 0.9004
364 8TX 0.9002
365 6E8 0.9001
366 EN1 0.9001
367 9UL 0.9001
368 YZ9 0.9000
369 M5H 0.8998
370 7FU 0.8997
371 KT7 0.8997
372 2EC 0.8996
373 LTM 0.8994
374 NLA 0.8994
375 KJ5 0.8993
376 54Z 0.8993
377 OA3 0.8993
378 6HP 0.8992
379 5V7 0.8991
380 NID 0.8990
381 TZF 0.8990
382 5JL 0.8989
383 505 0.8988
384 3VS 0.8987
385 R9Y 0.8986
386 BP7 0.8985
387 XDK 0.8985
388 7L4 0.8984
389 URC 0.8984
390 BTY 0.8983
391 DDU 0.8983
392 BBK 0.8982
393 P0P 0.8981
394 JY2 0.8981
395 6FZ 0.8980
396 8IG 0.8979
397 RVE 0.8978
398 JND 0.8977
399 GXY 0.8977
400 B55 0.8977
401 JU2 0.8977
402 75K 0.8975
403 78Y 0.8975
404 9CE 0.8975
405 ZON 0.8974
406 MQG 0.8973
407 5RN 0.8972
408 VNL 0.8970
409 RH1 0.8969
410 DIN 0.8968
411 QMS 0.8968
412 VUP 0.8968
413 HHT 0.8968
414 K2T 0.8966
415 MS9 0.8965
416 2J1 0.8965
417 KMY 0.8964
418 PYU 0.8963
419 JYB 0.8961
420 GVY 0.8961
421 XIY 0.8960
422 0FN 0.8960
423 FWD 0.8959
424 B52 0.8958
425 4VS 0.8958
426 HKD 0.8957
427 DNC 0.8956
428 FTV 0.8955
429 LFN 0.8955
430 7B3 0.8954
431 NRA 0.8954
432 RZH 0.8954
433 9LI 0.8954
434 LUM 0.8953
435 5XC 0.8951
436 MAQ 0.8949
437 NFM 0.8949
438 6VD 0.8947
439 15L 0.8945
440 8U3 0.8945
441 MRW 0.8944
442 CWD 0.8944
443 X8D 0.8942
444 1M2 0.8941
445 SBK 0.8939
446 SQ4 0.8939
447 HQD 0.8938
448 EV2 0.8938
449 VOH 0.8932
450 S7G 0.8931
451 JAH 0.8931
452 LNR 0.8930
453 P9E 0.8930
454 BZ3 0.8930
455 A7W 0.8928
456 TOF 0.8928
457 9KT 0.8927
458 4NB 0.8927
459 E7S 0.8927
460 F9Y 0.8926
461 3GC 0.8925
462 7MX 0.8924
463 DEW 0.8924
464 Z5P 0.8923
465 F4K 0.8923
466 4NO 0.8922
467 SRO 0.8921
468 CTE 0.8921
469 DPZ 0.8920
470 JXT 0.8920
471 2SX 0.8920
472 AY4 0.8920
473 ZME 0.8919
474 TCR 0.8919
475 FPL 0.8919
476 4R1 0.8918
477 7O4 0.8917
478 0XT 0.8914
479 PVK 0.8914
480 OUB 0.8914
481 LI6 0.8913
482 E7Z 0.8913
483 86L 0.8913
484 MUK 0.8912
485 5VL 0.8912
486 PVQ 0.8912
487 SNG 0.8912
488 DXK 0.8911
489 MFR 0.8910
490 CNI 0.8909
491 RB2 0.8909
492 F4E 0.8906
493 5AD 0.8906
494 K68 0.8905
495 6BL 0.8904
496 XM5 0.8904
497 4LW 0.8904
498 CIY 0.8903
499 N4E 0.8903
500 GI3 0.8903
501 TRP 0.8902
502 UAN 0.8901
503 2PV 0.8901
504 MAG 0.8900
505 ES5 0.8900
506 LO1 0.8900
507 1DR 0.8900
508 SQ7 0.8899
509 N3W 0.8899
510 K7H 0.8897
511 SYE 0.8896
512 327 0.8895
513 DEE 0.8894
514 GC3 0.8894
515 64E 0.8894
516 Z21 0.8894
517 DX2 0.8894
518 G6P 0.8893
519 BG6 0.8893
520 I4D 0.8892
521 5JQ 0.8890
522 MJ5 0.8890
523 CLU 0.8890
524 2D2 0.8889
525 S2P 0.8889
526 NOK 0.8888
527 RNO 0.8888
528 NGT 0.8888
529 LGT 0.8887
530 4Z4 0.8886
531 5JT 0.8886
532 HC4 0.8885
533 II4 0.8885
534 7MW 0.8885
535 P81 0.8884
536 JXN 0.8884
537 M6P 0.8884
538 OCH 0.8883
539 5QX 0.8883
540 D9Z 0.8882
541 92G 0.8882
542 I3A 0.8881
543 NQH 0.8880
544 7W1 0.8880
545 HRD 0.8880
546 JB5 0.8879
547 B60 0.8879
548 5OB 0.8879
549 ETV 0.8878
550 INO 0.8877
551 774 0.8876
552 KLK 0.8875
553 CH8 0.8875
554 DHY 0.8875
555 NHT 0.8874
556 W8G 0.8874
557 CPZ 0.8873
558 J9T 0.8873
559 H7Y 0.8873
560 2UZ 0.8872
561 JTH 0.8872
562 03V 0.8871
563 4FS 0.8871
564 AZ9 0.8871
565 SYA 0.8870
566 MXD 0.8869
567 96U 0.8869
568 535 0.8869
569 JY4 0.8867
570 H42 0.8866
571 2LB 0.8865
572 HPT 0.8865
573 8D6 0.8864
574 36E 0.8864
575 TYL 0.8864
576 7MU 0.8863
577 IWT 0.8863
578 PLR 0.8863
579 C53 0.8862
580 IOP 0.8861
581 LDP 0.8861
582 4ME 0.8860
583 SNO 0.8859
584 92K 0.8859
585 MFZ 0.8859
586 Z25 0.8859
587 J9Q 0.8857
588 CG 0.8856
589 1Z6 0.8856
590 4HB 0.8856
591 PLP 0.8856
592 DHB 0.8856
593 GB4 0.8855
594 A5H 0.8855
595 EXR 0.8855
596 2PK 0.8854
597 M1Q 0.8854
598 DAH 0.8854
599 M2K 0.8853
600 KTJ 0.8853
601 2AQ 0.8851
602 GA2 0.8851
603 M3Q 0.8851
604 PDC 0.8851
605 G14 0.8851
606 COU 0.8849
607 LZB 0.8849
608 EXL 0.8848
609 NNO 0.8847
610 0UL 0.8847
611 KYN 0.8847
612 R2P 0.8847
613 H4E 0.8845
614 XFE 0.8845
615 M3F 0.8844
616 6HO 0.8844
617 DUR 0.8844
618 1L5 0.8844
619 PD2 0.8842
620 LQ2 0.8841
621 6L6 0.8840
622 FZM 0.8840
623 96Z 0.8840
624 AP6 0.8839
625 VM1 0.8838
626 P7Y 0.8838
627 M1Z 0.8837
628 5E5 0.8837
629 L1O 0.8837
630 93K 0.8837
631 4WF 0.8837
632 I2E 0.8836
633 3PF 0.8834
634 6X9 0.8834
635 NPS 0.8833
636 AJ1 0.8833
637 LIP 0.8833
638 NPX 0.8832
639 DHC 0.8831
640 6RQ 0.8831
641 36Y 0.8831
642 IQZ 0.8831
643 QBM 0.8831
644 FHB 0.8830
645 B4O 0.8829
646 0BP 0.8828
647 K3Q 0.8827
648 EYJ 0.8827
649 MO8 0.8825
650 EAE 0.8824
651 NGW 0.8824
652 PYQ 0.8823
653 HQT 0.8823
654 GDE 0.8821
655 J9W 0.8821
656 PQK 0.8821
657 HWD 0.8820
658 4A3 0.8820
659 PUE 0.8820
660 DTR 0.8820
661 CPW 0.8820
662 XQK 0.8819
663 BWD 0.8819
664 7WR 0.8818
665 GLP 0.8818
666 8VR 0.8818
667 ALX 0.8817
668 42J 0.8817
669 54E 0.8817
670 FER 0.8816
671 GNG 0.8816
672 MMS 0.8815
673 HHH 0.8815
674 BZE 0.8815
675 AX3 0.8814
676 J5I 0.8814
677 DCZ 0.8814
678 GNY 0.8813
679 TXW 0.8812
680 M02 0.8812
681 CCV 0.8811
682 S8A 0.8811
683 78U 0.8811
684 9KZ 0.8810
685 JR2 0.8810
686 P4L 0.8810
687 TYR 0.8810
688 1P7 0.8809
689 2FD 0.8809
690 2A9 0.8808
691 CGW 0.8807
692 QMR 0.8807
693 PZP 0.8805
694 PLP PMP 0.8805
695 4OG 0.8805
696 HNM 0.8804
697 ST4 0.8803
698 F6P 0.8801
699 4NC 0.8801
700 5VM 0.8800
701 55D 0.8800
702 92O 0.8798
703 0SY 0.8798
704 ONR 0.8797
705 AH9 0.8796
706 R6T 0.8796
707 AAN 0.8796
708 JA5 0.8796
709 6J9 0.8795
710 SE2 0.8795
711 FT2 0.8795
712 DJN 0.8795
713 G3E 0.8794
714 4AN 0.8794
715 64C 0.8793
716 BNL 0.8793
717 2JX 0.8792
718 K82 0.8792
719 VK3 0.8792
720 4XV 0.8791
721 PXP 0.8791
722 K37 0.8790
723 Q24 0.8790
724 M6Z 0.8790
725 2D0 0.8788
726 MUR 0.8788
727 AZM 0.8788
728 4B0 0.8788
729 3HM 0.8787
730 BGP 0.8786
731 3C4 0.8786
732 BGN 0.8785
733 4MU 0.8784
734 LL1 0.8784
735 5MD 0.8784
736 YIH 0.8784
737 4HC 0.8784
738 YF3 0.8783
739 3D1 0.8783
740 MYI 0.8783
741 5O5 0.8783
742 S0G 0.8782
743 5UD 0.8782
744 CTS 0.8782
745 OSB 0.8781
746 EMO 0.8779
747 7ME 0.8777
748 4M4 0.8777
749 STX 0.8777
750 46P 0.8777
751 4HP 0.8777
752 IPD 0.8776
753 CMU 0.8776
754 36M 0.8775
755 FDB 0.8775
756 T1N 0.8775
757 2HO 0.8775
758 ET2 0.8774
759 APG 0.8774
760 E3X 0.8773
761 ES2 0.8772
762 3CR 0.8772
763 36R 0.8770
764 ODO 0.8770
765 JGB 0.8770
766 M6N 0.8769
767 CL9 0.8769
768 12Q 0.8768
769 1VK 0.8768
770 L46 0.8767
771 4FE 0.8767
772 WV7 0.8767
773 HJB 0.8767
774 J9N 0.8766
775 0F9 0.8766
776 FLV 0.8766
777 AQO 0.8765
778 NBG 0.8765
779 SKA 0.8764
780 IWD 0.8763
781 CSN 0.8763
782 L5V 0.8762
783 BB4 0.8762
784 LR8 0.8761
785 4V6 0.8761
786 LEL 0.8760
787 0NX 0.8759
788 CTL 0.8759
789 V55 0.8759
790 CHB 0.8758
791 EPR 0.8757
792 B1J 0.8754
793 Q7A 0.8754
794 BDP 0.8754
795 JCZ 0.8754
796 4NP 0.8753
797 A6P 0.8753
798 8XQ 0.8753
799 52C 0.8752
800 GC2 0.8752
801 HX4 0.8752
802 ANN 0.8751
803 HSX 0.8751
804 069 0.8751
805 TJM 0.8751
806 JRB 0.8749
807 MPV 0.8749
808 YOF 0.8749
809 4AA 0.8749
810 RM1 0.8748
811 MIG 0.8748
812 L7T 0.8748
813 URI 0.8747
814 9RW 0.8747
815 BGC 0.8747
816 CLW 0.8746
817 XX2 0.8746
818 GI1 0.8745
819 ABF 0.8745
820 L1Q 0.8744
821 CTN 0.8744
822 GCS 0.8744
823 F40 0.8742
824 8GK 0.8742
825 NIY 0.8741
826 MYJ 0.8741
827 PE0 0.8740
828 DTY 0.8740
829 GJK 0.8738
830 DRL 0.8738
831 5OF 0.8738
832 H70 0.8737
833 JRO 0.8737
834 KIB 0.8737
835 SMN 0.8736
836 49O 0.8736
837 XQ0 0.8735
838 5XL 0.8735
839 NHG 0.8735
840 L5E 0.8734
841 5B1 0.8732
842 4AU 0.8732
843 GCB 0.8732
844 PQZ 0.8731
845 K4V 0.8729
846 GZ8 0.8729
847 3XR 0.8729
848 SYV 0.8728
849 MNP 0.8726
850 AJ2 0.8725
851 3R6 0.8725
852 TYE 0.8725
853 SKM 0.8724
854 AZ8 0.8724
855 AMQ 0.8724
856 MDR 0.8723
857 226 0.8723
858 TZM 0.8723
859 8DA 0.8723
860 263 0.8722
861 6R8 0.8721
862 DX1 0.8721
863 GVG 0.8721
864 PIQ 0.8720
865 4NS 0.8720
866 MEW 0.8719
867 MR1 0.8718
868 EZL 0.8717
869 XI7 0.8717
870 2D3 0.8717
871 NDM 0.8716
872 EA1 0.8716
873 QBP 0.8716
874 SHA 0.8716
875 KGK 0.8716
876 M5K 0.8715
877 P80 0.8715
878 C8O 0.8715
879 SXS 0.8714
880 56D 0.8714
881 6ZW 0.8712
882 4WL 0.8712
883 6DP 0.8712
884 LT2 0.8710
885 TQU 0.8710
886 TTL 0.8710
887 AKD 0.8710
888 GCU 0.8709
889 RXA 0.8707
890 S7J 0.8707
891 M0W 0.8707
892 J38 0.8706
893 G1P 0.8705
894 QPR 0.8704
895 7VS 0.8703
896 NGO 0.8703
897 X0V 0.8703
898 IHB 0.8703
899 I59 0.8702
900 I6G 0.8702
901 FBF 0.8700
902 8G6 0.8700
903 X09 0.8699
904 F31 0.8698
905 7ZE 0.8698
906 YO5 0.8697
907 F69 0.8697
908 YE7 0.8695
909 2J2 0.8695
910 THM 0.8695
911 PNZ 0.8695
912 KJU 0.8694
913 PNP 0.8693
914 NQ 0.8693
915 96R 0.8693
916 I3E 0.8692
917 Q0K 0.8691
918 LR5 0.8691
919 QSB 0.8691
920 4M0 0.8690
921 4JT 0.8690
922 YZM 0.8690
923 B0K 0.8689
924 173 0.8688
925 7MK 0.8688
926 4ZA 0.8687
927 ALN 0.8687
928 3D8 0.8687
929 39Z 0.8686
930 X05 0.8686
931 IS2 0.8686
932 RLG 0.8686
933 QAS 0.8685
934 9TW 0.8684
935 GZL 0.8684
936 F0J 0.8683
937 3GQ 0.8683
938 OW7 0.8682
939 GJS 0.8682
940 EMZ 0.8681
941 2F8 0.8680
942 CWM 0.8678
943 5VJ 0.8678
944 QAT 0.8678
945 M0Q 0.8677
946 NDH 0.8676
947 GAL 0.8676
948 NSG 0.8675
949 9H2 0.8675
950 IQ5 0.8674
951 091 0.8674
952 372 0.8672
953 P9P 0.8672
954 R9S 0.8672
955 RA7 0.8669
956 9FH 0.8668
957 COL 0.8668
958 D3G 0.8667
959 2CL 0.8666
960 A5P 0.8666
961 BHA 0.8663
962 3RI 0.8663
963 LAO 0.8663
964 P1J 0.8661
965 R20 0.8660
966 A1Y 0.8658
967 GLC 0.8657
968 BBY 0.8657
969 SOR 0.8657
970 J4K 0.8657
971 FMQ 0.8656
972 EQU 0.8654
973 7D7 0.8654
974 OMD 0.8654
975 FA0 0.8653
976 5TZ 0.8653
977 EVA 0.8652
978 7VP 0.8652
979 GF1 0.8652
980 5SJ 0.8651
981 STT 0.8651
982 DOB 0.8649
983 G3F 0.8648
984 H4B NO 0.8648
985 IFP 0.8648
986 80G 0.8645
987 N2Z 0.8645
988 HQJ 0.8645
989 OTA 0.8644
990 VGD 0.8643
991 VC3 0.8642
992 NPL 0.8642
993 EKZ 0.8642
994 AVX 0.8641
995 FHC 0.8640
996 4P5 0.8640
997 3DM 0.8639
998 4NR 0.8637
999 M1H 0.8637
1000 IA2 0.8637
1001 QQQ 0.8637
1002 AH6 0.8636
1003 5WY 0.8636
1004 GOE 0.8635
1005 LGC 0.8634
1006 AEG 0.8634
1007 RUY 0.8634
1008 1XA 0.8634
1009 DBS 0.8633
1010 89J 0.8632
1011 ZRK 0.8632
1012 IPT 0.8632
1013 9NB 0.8630
1014 ADN 0.8630
1015 PO6 0.8630
1016 8S0 0.8629
1017 S3C 0.8628
1018 5QY 0.8626
1019 1V4 0.8626
1020 HL4 0.8625
1021 TCA 0.8624
1022 5GU 0.8624
1023 M83 0.8623
1024 EUH 0.8622
1025 S7S 0.8622
1026 SHI 0.8621
1027 1V3 0.8620
1028 CP6 0.8620
1029 2B4 0.8620
1030 MWP 0.8617
1031 3IT 0.8616
1032 NCT 0.8613
1033 YIE 0.8613
1034 PRZ 0.8612
1035 F1A 0.8612
1036 GZQ 0.8609
1037 5WN 0.8607
1038 BY5 0.8606
1039 TB8 0.8606
1040 Q88 0.8605
1041 EST 0.8601
1042 293 0.8601
1043 GWM 0.8596
1044 ZVO 0.8595
1045 TIA 0.8595
1046 1V1 0.8595
1047 42C 0.8595
1048 9FQ 0.8593
1049 CP7 0.8592
1050 SDF 0.8592
1051 TRF 0.8592
1052 HIS 0.8591
1053 A73 0.8590
1054 BZQ 0.8588
1055 HCI 0.8588
1056 DHK 0.8587
1057 A5Q 0.8587
1058 XIZ 0.8586
1059 4CM 0.8583
1060 XRS 0.8581
1061 4MB 0.8580
1062 PH3 0.8580
1063 TLM 0.8578
1064 UQ1 0.8578
1065 WUB 0.8577
1066 GTQ 0.8575
1067 6MW 0.8572
1068 GB5 0.8571
1069 WOO 0.8568
1070 NCV 0.8565
1071 O2A 0.8563
1072 PTS 0.8562
1073 KJY 0.8562
1074 QSH 0.8560
1075 W81 0.8560
1076 4SX 0.8557
1077 SHG 0.8555
1078 MIL 0.8555
1079 3DO 0.8552
1080 UFV 0.8551
1081 DBQ 0.8550
1082 CB1 0.8548
1083 5CU 0.8547
1084 0W8 0.8545
1085 A7N 0.8544
1086 HJ7 0.8538
1087 IQW 0.8538
1088 CUE 0.8535
1089 GNR 0.8533
1090 B09 0.8529
1091 HQ9 0.8527
1092 4A5 0.8527
1093 E3D 0.8523
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4NTM; Ligand: 2K8; Similar sites found with APoc: 6
This union binding pocket(no: 1) in the query (biounit: 4ntm.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 1Y13 BIO 37.1901
2 1Y13 BIO 37.1901
3 1Y13 BIO 37.1901
4 1Y13 BIO 37.1901
5 1Y13 BIO 37.1901
6 1Y13 BIO 37.1901
Pocket No.: 2; Query (leader) PDB : 4NTM; Ligand: 2K8; Similar sites found with APoc: 5
This union binding pocket(no: 2) in the query (biounit: 4ntm.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 1Y13 BIO 37.1901
2 1Y13 BIO 37.1901
3 1Y13 BIO 37.1901
4 1Y13 BIO 37.1901
5 1Y13 BIO 37.1901
Pocket No.: 3; Query (leader) PDB : 4NTM; Ligand: 2K8; Similar sites found with APoc: 5
This union binding pocket(no: 3) in the query (biounit: 4ntm.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 1Y13 BIO 37.1901
2 1Y13 BIO 37.1901
3 1Y13 BIO 37.1901
4 1Y13 BIO 37.1901
5 1Y13 BIO 37.1901
Pocket No.: 4; Query (leader) PDB : 4NTM; Ligand: 2K8; Similar sites found with APoc: 6
This union binding pocket(no: 4) in the query (biounit: 4ntm.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 1Y13 BIO 37.1901
2 1Y13 BIO 37.1901
3 1Y13 BIO 37.1901
4 1Y13 BIO 37.1901
5 1Y13 BIO 37.1901
6 1Y13 BIO 37.1901
Pocket No.: 5; Query (leader) PDB : 4NTM; Ligand: 2K8; Similar sites found with APoc: 6
This union binding pocket(no: 5) in the query (biounit: 4ntm.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 1Y13 BIO 37.1901
2 1Y13 BIO 37.1901
3 1Y13 BIO 37.1901
4 1Y13 BIO 37.1901
5 1Y13 BIO 37.1901
6 1Y13 BIO 37.1901
Pocket No.: 6; Query (leader) PDB : 4NTM; Ligand: 2K8; Similar sites found with APoc: 6
This union binding pocket(no: 6) in the query (biounit: 4ntm.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 1Y13 BIO 37.1901
2 1Y13 BIO 37.1901
3 1Y13 BIO 37.1901
4 1Y13 BIO 37.1901
5 1Y13 BIO 37.1901
6 1Y13 BIO 37.1901
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