Receptor
PDB id Resolution Class Description Source Keywords
4p0a 2.3 Å EC: 6.3.2.- CRYSTAL STRUCTURE OF HOIP PUB DOMAIN IN COMPLEX WITH P97 PIM HOMO SAPIENS HOIP PUB DOMAIN P97 PIM LIGASE
Ref.: BINDING OF OTULIN TO THE PUB DOMAIN OF HOIP CONTROL NF-KAPPA B SIGNALING. MOL.CELL V. 54 349 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
THR GLU ASP ASN ASP ASP ASP LEU TYR GLY D:803;
B:803;
 Valid;
Valid;
 none;
none;
 Kd = 30.3 uM
n/a n/a
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4P0A 2.3 Å EC: 6.3.2.- CRYSTAL STRUCTURE OF HOIP PUB DOMAIN IN COMPLEX WITH P97 PIM HOMO SAPIENS HOIP PUB DOMAIN P97 PIM LIGASE
Ref.: BINDING OF OTULIN TO THE PUB DOMAIN OF HOIP CONTROL NF-KAPPA B SIGNALING. MOL.CELL V. 54 349 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 41 families.
1 4P0A Kd = 30.3 uM THR GLU ASP ASN ASP ASP ASP LEU TYR GLY n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 27 families.
1 4P0A Kd = 30.3 uM THR GLU ASP ASN ASP ASP ASP LEU TYR GLY n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 21 families.
1 4P0A Kd = 30.3 uM THR GLU ASP ASN ASP ASP ASP LEU TYR GLY n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: THR GLU ASP ASN ASP ASP ASP LEU TYR GLY; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Ligands (3D)
Ligand no: 1; Ligand: THR GLU ASP ASN ASP ASP ASP LEU TYR GLY; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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