Receptor
PDB id Resolution Class Description Source Keywords
4yrn 2.2 Å EC: 6.1.1.21 CRYSTAL STRUCTURE OF T. CRUZI HISTIDYL-TRNA SYNTHETASE IN CO 6-BROMOPYRIDIN-3-AMINE (CHEM 475) TRYPANOSOMA CRUZI (STRAIN CL BRENER) LIGASE AMINOACYL-TRNA SYNTHETASE AARS HISRS TRYPANOSOMA PROTEIN-INHIBITOR COMPLEX LIGASE-LIGASE INHIBITOR COMPLEX
Ref.: A BINDING HOTSPOT IN TRYPANOSOMA CRUZI HISTIDYL-TRN SYNTHETASE REVEALED BY FRAGMENT-BASED CRYSTALLOGRAP COCKTAIL SCREENS. ACTA CRYSTALLOGR. D BIOL. V. 71 1684 2015 CRYSTALLOGR.
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SO4 A:507;
A:508;
A:506;
B:510;
B:511;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
 submit data
96.063 O4 S [O-]S...
DMS A:503;
B:503;
B:504;
B:505;
A:504;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
 submit data
78.133 C2 H6 O S CS(=O...
EDO A:505;
B:508;
B:507;
B:509;
B:506;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
 submit data
62.068 C2 H6 O2 C(CO)...
4JN B:502;
A:502;
 Valid;
Valid;
 none;
none;
 submit data
173.011 C5 H5 Br N2 c1cc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4YRI 2 Å EC: 6.1.1.21 CRYSTAL STRUCTURE OF T. CRUZI HISTIDYL-TRNA SYNTHETASE IN CO 1-(3-BROMOPHENYL)METHANAMINE (CHEM 166) TRYPANOSOMA CRUZI (STRAIN CL BRENER) LIGASE AMINOACYL-TRNA SYNTHETASE AARS HISRS TRYPANOSOMA PROTEIN-INHIBITOR COMPLEX LIGASE-LIGASE INHIBITOR COMPLEX
Ref.: A BINDING HOTSPOT IN TRYPANOSOMA CRUZI HISTIDYL-TRN SYNTHETASE REVEALED BY FRAGMENT-BASED CRYSTALLOGRAP COCKTAIL SCREENS. ACTA CRYSTALLOGR. D BIOL. V. 71 1684 2015 CRYSTALLOGR.
Members (16)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4YRI - 4JH C7 H8 Br N c1cc(cc(c1....
2 4YRF - 4HS C5 H4 Br N O C1=CC(=O)N....
3 4YRP - PZH C7 H8 Br N c1cc(ccc1C....
4 4YRC - 0P6 C9 H8 N2 O c1cc2ccc(n....
5 4YRJ - 4JJ C6 H7 Cl N2 c1cc(c(cc1....
6 4YRQ - 4JQ C9 H7 N O2 c1cc2c(cc1....
7 4YP0 - 5IQ C9 H8 N2 c1cc2cnccc....
8 4YRM - 282 C6 H7 N O COc1cccnc1
9 4YRL - 4JM C7 H9 N S CSc1ccc(cc....
10 4YPF - 4FS C9 H8 N2 c1ccc2c(c1....
11 4YRE - 4HR C7 H7 Br O c1ccc(c(c1....
12 4YRN - 4JN C5 H5 Br N2 c1cc(ncc1N....
13 4YRK - 4JL C7 H7 Cl O c1cc(ccc1C....
14 4YRO - 4JO C6 H7 Br N2 Cc1c(ccc(n....
15 4YRR - 691 C11 H10 N2 O CC(=O)Nc1c....
16 4YRG - 4HU C6 H6 Br N O c1cc(nc(c1....
70% Homology Family (16)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4YRI - 4JH C7 H8 Br N c1cc(cc(c1....
2 4YRF - 4HS C5 H4 Br N O C1=CC(=O)N....
3 4YRP - PZH C7 H8 Br N c1cc(ccc1C....
4 4YRC - 0P6 C9 H8 N2 O c1cc2ccc(n....
5 4YRJ - 4JJ C6 H7 Cl N2 c1cc(c(cc1....
6 4YRQ - 4JQ C9 H7 N O2 c1cc2c(cc1....
7 4YP0 - 5IQ C9 H8 N2 c1cc2cnccc....
8 4YRM - 282 C6 H7 N O COc1cccnc1
9 4YRL - 4JM C7 H9 N S CSc1ccc(cc....
10 4YPF - 4FS C9 H8 N2 c1ccc2c(c1....
11 4YRE - 4HR C7 H7 Br O c1ccc(c(c1....
12 4YRN - 4JN C5 H5 Br N2 c1cc(ncc1N....
13 4YRK - 4JL C7 H7 Cl O c1cc(ccc1C....
14 4YRO - 4JO C6 H7 Br N2 Cc1c(ccc(n....
15 4YRR - 691 C11 H10 N2 O CC(=O)Nc1c....
16 4YRG - 4HU C6 H6 Br N O c1cc(nc(c1....
50% Homology Family (16)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4YRI - 4JH C7 H8 Br N c1cc(cc(c1....
2 4YRF - 4HS C5 H4 Br N O C1=CC(=O)N....
3 4YRP - PZH C7 H8 Br N c1cc(ccc1C....
4 4YRC - 0P6 C9 H8 N2 O c1cc2ccc(n....
5 4YRJ - 4JJ C6 H7 Cl N2 c1cc(c(cc1....
6 4YRQ - 4JQ C9 H7 N O2 c1cc2c(cc1....
7 4YP0 - 5IQ C9 H8 N2 c1cc2cnccc....
8 4YRM - 282 C6 H7 N O COc1cccnc1
9 4YRL - 4JM C7 H9 N S CSc1ccc(cc....
10 4YPF - 4FS C9 H8 N2 c1ccc2c(c1....
11 4YRE - 4HR C7 H7 Br O c1ccc(c(c1....
12 4YRN - 4JN C5 H5 Br N2 c1cc(ncc1N....
13 4YRK - 4JL C7 H7 Cl O c1cc(ccc1C....
14 4YRO - 4JO C6 H7 Br N2 Cc1c(ccc(n....
15 4YRR - 691 C11 H10 N2 O CC(=O)Nc1c....
16 4YRG - 4HU C6 H6 Br N O c1cc(nc(c1....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 4JN; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 4JN 1 1
2 DA1 0.481481 0.692308
Similar Ligands (3D)
Ligand no: 1; Ligand: 4JN; Similar ligands found: 720
No: Ligand Similarity coefficient
1 BML 1.0000
2 2MH 1.0000
3 4JU 1.0000
4 LG4 1.0000
5 PCR 1.0000
6 IOL 1.0000
7 4HS 1.0000
8 4CH 1.0000
9 PXY 0.9983
10 25R 0.9965
11 HQE 0.9951
12 PLQ 0.9932
13 FPN 0.9930
14 HBA 0.9750
15 H8N 0.9708
16 CYH 0.9689
17 4XX 0.9684
18 1PT 0.9676
19 PHB 0.9658
20 4VP 0.9655
21 1DH 0.9645
22 AMC 0.9637
23 CXL 0.9634
24 GXE 0.9634
25 A2Q 0.9619
26 HAI 0.9619
27 25T 0.9617
28 FPI 0.9616
29 27Y 0.9604
30 2IM 0.9603
31 TH0 0.9591
32 IPH 0.9591
33 4CL 0.9589
34 BR9 0.9588
35 4JJ 0.9583
36 MWJ 0.9579
37 275 0.9578
38 MBN 0.9578
39 HGW 0.9576
40 4HO 0.9575
41 8CL 0.9573
42 4JO 0.9573
43 IUR 0.9573
44 TTO 0.9568
45 PIH 0.9568
46 JZ2 0.9567
47 1MC 0.9567
48 4JM 0.9564
49 5MH 0.9563
50 V1L 0.9563
51 MZG 0.9562
52 TMZ 0.9559
53 3AP 0.9557
54 TDR 0.9553
55 2AP 0.9552
56 MCT 0.9550
57 C2B 0.9550
58 HBX 0.9548
59 5UC 0.9548
60 5JC 0.9547
61 WOT 0.9545
62 FPY 0.9537
63 ICP 0.9536
64 PYD 0.9536
65 282 0.9533
66 43M 0.9531
67 4JL 0.9531
68 HHN 0.9529
69 4AP 0.9529
70 Y8I 0.9522
71 BP9 0.9520
72 MZW 0.9519
73 A1U 0.9518
74 2AC 0.9518
75 XBZ 0.9514
76 IDH 0.9512
77 9PO 0.9512
78 FBA 0.9510
79 PYF 0.9509
80 HVK 0.9508
81 OHG 0.9501
82 URF 0.9500
83 XYD 0.9497
84 WBU 0.9493
85 HRZ 0.9492
86 LGA 0.9483
87 8H8 0.9481
88 TLD 0.9480
89 QOS 0.9478
90 LDU 0.9478
91 SYN 0.9477
92 ABN 0.9470
93 34A 0.9468
94 LXC 0.9462
95 HT4 0.9459
96 XYP 0.9452
97 4ZE 0.9444
98 CEJ 0.9440
99 TM7 0.9439
100 TMT 0.9438
101 2MP 0.9433
102 2YU 0.9428
103 CYS 0.9427
104 MWM 0.9426
105 ECE 0.9417
106 93B 0.9410
107 R2B 0.9392
108 J1Z 0.9391
109 1MR 0.9390
110 FYU 0.9389
111 PY7 0.9388
112 HYN 0.9386
113 L60 0.9373
114 4XR 0.9372
115 XIX 0.9370
116 CRS 0.9369
117 7EX 0.9361
118 NK 0.9359
119 938 0.9353
120 VAL 0.9349
121 DEN 0.9340
122 PYJ 0.9340
123 2CH 0.9339
124 HMH 0.9339
125 KIV 0.9334
126 0R0 0.9333
127 DMG 0.9328
128 280 0.9327
129 BEW 0.9324
130 6X8 0.9322
131 NBE 0.9320
132 JZ3 0.9317
133 11S 0.9315
134 ZZT 0.9315
135 DTU 0.9313
136 2KT 0.9310
137 HIU 0.9306
138 0R1 0.9305
139 9CL 0.9302
140 NSP 0.9300
141 IND 0.9295
142 GVH 0.9295
143 24T 0.9294
144 MZ0 0.9293
145 HTS 0.9290
146 BZF 0.9290
147 RSF 0.9289
148 93Q 0.9286
149 4JP 0.9285
150 0CT 0.9285
151 LZ1 0.9284
152 BZI 0.9283
153 CAQ 0.9281
154 MPI 0.9281
155 MAK 0.9278
156 6AI 0.9276
157 APY 0.9274
158 HGQ 0.9273
159 NVI 0.9271
160 HPY 0.9269
161 L89 0.9268
162 IDM 0.9265
163 TH7 0.9263
164 DGY 0.9261
165 1AN 0.9261
166 BZX 0.9259
167 OXE 0.9258
168 24B 0.9257
169 RCO 0.9257
170 9X7 0.9256
171 H4N 0.9256
172 2MI 0.9256
173 92Z 0.9255
174 FK1 0.9254
175 EDG 0.9253
176 B24 0.9253
177 ES9 0.9251
178 8LG 0.9249
179 AHR 0.9246
180 AX7 0.9245
181 270 0.9245
182 5MI 0.9242
183 FP2 0.9241
184 1AB 0.9239
185 23W 0.9238
186 3ZQ 0.9236
187 MLA 0.9236
188 P2D 0.9234
189 8NY 0.9233
190 MRY 0.9233
191 DSN 0.9233
192 KOJ 0.9232
193 3PY 0.9231
194 NPO 0.9228
195 Z82 0.9223
196 5MB 0.9222
197 2K4 0.9222
198 JZ0 0.9220
199 ICC 0.9219
200 F60 0.9217
201 LG3 0.9213
202 5H1 0.9212
203 PZM 0.9210
204 14O 0.9210
205 XYS 0.9209
206 PYG 0.9207
207 284 0.9202
208 3MC 0.9198
209 CYT 0.9193
210 3CH 0.9193
211 URA 0.9192
212 MLI 0.9189
213 MBD 0.9181
214 23A 0.9180
215 BVF 0.9178
216 ABV 0.9176
217 HEW 0.9176
218 2AF 0.9170
219 DUC 0.9169
220 3CE 0.9166
221 BAQ 0.9163
222 1CB 0.9160
223 PBZ 0.9158
224 RIB 0.9156
225 26D 0.9155
226 KG7 0.9153
227 HHQ 0.9151
228 JZ9 0.9149
229 F81 0.9146
230 PAB 0.9146
231 HMU 0.9146
232 PRO 0.9144
233 76X 0.9144
234 B3R 0.9144
235 JFD 0.9144
236 P92 0.9144
237 3FA 0.9142
238 FFP 0.9141
239 GMN 0.9140
240 2C9 0.9136
241 KSW 0.9130
242 JAE 0.9129
243 HX3 0.9128
244 2CM 0.9127
245 MAE 0.9123
246 FLM 0.9119
247 LG5 0.9118
248 717 0.9118
249 2MY 0.9117
250 HSL 0.9114
251 3MT 0.9113
252 AC6 0.9113
253 JZ1 0.9112
254 FUC 0.9111
255 M3T 0.9111
256 DXX 0.9109
257 1DU 0.9109
258 T6C 0.9105
259 BAM 0.9105
260 THR 0.9102
261 FUL 0.9102
262 0MK 0.9101
263 40O 0.9099
264 HBD 0.9099
265 BEN 0.9097
266 8GF 0.9097
267 SER 0.9096
268 6MH 0.9095
269 AMT 0.9095
270 1Y6 0.9095
271 BEZ 0.9092
272 4MZ 0.9092
273 BVG 0.9092
274 286 0.9090
275 4MA 0.9090
276 NBZ 0.9090
277 P72 0.9088
278 MB3 0.9088
279 3DM 0.9087
280 E60 0.9086
281 174 0.9085
282 NCA 0.9085
283 BVC 0.9079
284 35C 0.9079
285 MMZ 0.9077
286 2MZ 0.9077
287 H3M 0.9076
288 GBL 0.9075
289 QUZ 0.9074
290 RIP 0.9073
291 7CZ 0.9072
292 NIO 0.9072
293 ATQ 0.9071
294 YRL 0.9069
295 4H2 0.9067
296 2CQ 0.9063
297 FOA 0.9063
298 3TR 0.9062
299 PCA 0.9062
300 1MZ 0.9061
301 JIF 0.9061
302 PZA 0.9059
303 OAA 0.9059
304 GLC 0.9058
305 CIG 0.9056
306 HOW 0.9055
307 SIN 0.9053
308 HSE 0.9053
309 826 0.9052
310 ALO 0.9051
311 TP5 0.9050
312 GOL 0.9049
313 PYZ 0.9048
314 HSM 0.9047
315 285 0.9047
316 2AI 0.9045
317 XM0 0.9043
318 YCP 0.9042
319 DUB 0.9040
320 DFU 0.9035
321 NPY 0.9034
322 TBP 0.9033
323 BYZ 0.9031
324 5KX 0.9030
325 ARB 0.9030
326 FQI 0.9029
327 6PC 0.9027
328 PEA 0.9026
329 HVQ 0.9025
330 P3K 0.9024
331 F4Z 0.9021
332 5MP 0.9021
333 0TR 0.9021
334 2PC 0.9020
335 ABA 0.9020
336 3MH 0.9018
337 BSX 0.9018
338 NTN 0.9017
339 TC7 0.9017
340 MEU 0.9017
341 SW7 0.9016
342 4FA 0.9015
343 ES3 0.9014
344 14J 0.9012
345 JZ6 0.9011
346 69O 0.9011
347 ABE 0.9010
348 HX2 0.9009
349 DTI 0.9008
350 7MH 0.9008
351 MR3 0.9007
352 FAN 0.9006
353 PBC 0.9004
354 MMU 0.9003
355 MZY 0.9000
356 PYC 0.9000
357 C5J 0.8998
358 TM4 0.8992
359 LMR 0.8990
360 DMI 0.8989
361 NEQ 0.8984
362 265 0.8984
363 2HA 0.8984
364 1XX 0.8980
365 R8A 0.8980
366 45C 0.8980
367 M1A 0.8978
368 TFB 0.8978
369 1WG 0.8974
370 4AX 0.8970
371 RSO 0.8970
372 278 0.8968
373 DFB 0.8965
374 UNU 0.8963
375 94N 0.8963
376 5VM 0.8961
377 IMR 0.8961
378 67N 0.8960
379 5OB 0.8959
380 BZ3 0.8959
381 7WG 0.8956
382 LER 0.8955
383 YHO 0.8955
384 PRI 0.8954
385 36R 0.8954
386 XRG 0.8953
387 VGL 0.8952
388 AC0 0.8952
389 NOJ 0.8952
390 5AC 0.8951
391 B53 0.8950
392 OXQ 0.8947
393 YAN 0.8947
394 PYR 0.8947
395 273 0.8944
396 CLW 0.8944
397 JBN 0.8942
398 9YL 0.8941
399 150 0.8940
400 GAG 0.8936
401 2RA 0.8933
402 JAB 0.8933
403 R1X 0.8932
404 F05 0.8930
405 3XX 0.8929
406 TZC 0.8927
407 9TY 0.8927
408 5WV 0.8925
409 JZ5 0.8924
410 GBD 0.8923
411 2CK 0.8920
412 VGD 0.8920
413 RP7 0.8919
414 G6D 0.8918
415 4BZ 0.8911
416 ET2 0.8910
417 AGK 0.8910
418 HY3 0.8910
419 261 0.8906
420 C21 0.8905
421 AEF 0.8904
422 ABU 0.8904
423 3ZS 0.8903
424 DBB 0.8902
425 A3B 0.8902
426 M58 0.8901
427 FCA 0.8900
428 DCY 0.8898
429 BNZ 0.8893
430 DGJ 0.8893
431 LEA 0.8891
432 C2N 0.8891
433 60P 0.8890
434 OXZ 0.8890
435 2A9 0.8890
436 OXL 0.8890
437 4SV 0.8889
438 03W 0.8888
439 QSC 0.8886
440 SAL 0.8884
441 HUI 0.8883
442 2EZ 0.8882
443 DHR 0.8879
444 BTE 0.8879
445 B20 0.8879
446 6SP 0.8878
447 1AC 0.8877
448 SS1 0.8875
449 4M0 0.8875
450 SS2 0.8874
451 PHZ 0.8872
452 OXM 0.8871
453 3U4 0.8871
454 RBJ 0.8866
455 URP 0.8865
456 BHA 0.8864
457 IFL 0.8864
458 5NU 0.8862
459 0PY 0.8858
460 3OH 0.8857
461 HDA 0.8856
462 E5X 0.8852
463 AZF 0.8852
464 9EW 0.8852
465 1DW 0.8851
466 XQ0 0.8850
467 DOB 0.8850
468 PEL 0.8850
469 K2T 0.8849
470 HLR 0.8849
471 FBB 0.8848
472 JBE 0.8847
473 ES6 0.8846
474 XBT 0.8845
475 BE2 0.8844
476 1P8 0.8843
477 FP1 0.8842
478 C2A 0.8841
479 FLA 0.8841
480 MLT 0.8840
481 5CU 0.8839
482 AKB 0.8838
483 FA0 0.8838
484 IFM 0.8838
485 HPA 0.8834
486 GAL 0.8833
487 BNS 0.8833
488 7W4 0.8831
489 GIF 0.8830
490 SMV 0.8826
491 PM6 0.8824
492 BPN 0.8822
493 P1R 0.8822
494 ES4 0.8821
495 RUU 0.8819
496 3Z7 0.8817
497 BAL 0.8814
498 PNZ 0.8813
499 ES2 0.8811
500 FUF 0.8811
501 ITU 0.8811
502 HCS 0.8809
503 OXD 0.8807
504 0RW 0.8806
505 6MP 0.8806
506 1M2 0.8806
507 ADE 0.8805
508 XIY 0.8804
509 F9Y 0.8803
510 MR1 0.8802
511 9DA 0.8802
512 3V4 0.8800
513 H42 0.8800
514 CXF 0.8799
515 6M9 0.8799
516 4FS 0.8799
517 YH7 0.8799
518 03V 0.8798
519 LAC 0.8798
520 T2C 0.8797
521 ES7 0.8796
522 SWD 0.8795
523 ISN 0.8795
524 3SK 0.8795
525 4NM 0.8794
526 192 0.8792
527 HY1 0.8791
528 SEJ 0.8789
529 TLA 0.8789
530 2AQ 0.8787
531 IPB 0.8786
532 PRS 0.8785
533 10L 0.8783
534 ADZ 0.8783
535 M6W 0.8781
536 CEE 0.8780
537 ES5 0.8780
538 SVN 0.8780
539 1WD 0.8778
540 G4D 0.8778
541 ALA 0.8777
542 ZBT 0.8776
543 0CU 0.8776
544 RHU 0.8776
545 7WA 0.8770
546 SN4 0.8770
547 AAE 0.8770
548 IT2 0.8770
549 COU 0.8769
550 UY7 0.8767
551 PAE 0.8767
552 259 0.8767
553 1XM 0.8765
554 ILE 0.8765
555 PYM 0.8763
556 BP1 0.8763
557 BUO 0.8761
558 FUB 0.8761
559 SAR 0.8760
560 HYP 0.8760
561 ANN 0.8760
562 WDL 0.8760
563 7HP 0.8759
564 JZ7 0.8758
565 82I 0.8756
566 VNJ 0.8756
567 SGL 0.8752
568 FCB 0.8750
569 CSS 0.8749
570 4P5 0.8748
571 9HX 0.8748
572 KKN 0.8748
573 7B4 0.8746
574 HH5 0.8745
575 JB5 0.8743
576 5Y9 0.8742
577 260 0.8741
578 G2F 0.8741
579 DTL 0.8741
580 OK7 0.8740
581 JKE 0.8739
582 Q88 0.8738
583 YTB 0.8737
584 HGY 0.8734
585 CWM 0.8733
586 UGC 0.8732
587 RNS 0.8731
588 BAE 0.8727
589 BCP 0.8724
590 ARA 0.8722
591 ASO 0.8720
592 A2F 0.8720
593 4ZC 0.8719
594 AX2 0.8718
595 ES0 0.8717
596 9DG 0.8716
597 GOO 0.8716
598 2DR 0.8714
599 MNM 0.8709
600 2D0 0.8708
601 2BG 0.8708
602 Z6J 0.8707
603 LCN 0.8706
604 IP0 0.8706
605 DHB 0.8705
606 NOY 0.8704
607 2HO 0.8702
608 6UA 0.8702
609 OCH 0.8701
610 6M4 0.8701
611 2LP 0.8700
612 4NC 0.8698
613 CRN 0.8698
614 AZA 0.8697
615 2ZX 0.8696
616 DYA 0.8694
617 ITN 0.8689
618 4A3 0.8689
619 BOA 0.8689
620 IF7 0.8687
621 GUN 0.8687
622 SRT 0.8686
623 CHB 0.8684
624 M2H 0.8682
625 XXR 0.8682
626 INO 0.8681
627 93K 0.8681
628 FW5 0.8681
629 47J 0.8680
630 ASN 0.8679
631 BUA 0.8674
632 P9P 0.8672
633 DX4 0.8672
634 9TW 0.8671
635 6AP 0.8669
636 SAN 0.8669
637 DBH 0.8668
638 JBK 0.8666
639 7WV 0.8666
640 5AN 0.8664
641 13X 0.8661
642 QSB 0.8660
643 DAL 0.8660
644 3AY 0.8658
645 3F0 0.8658
646 QXW 0.8657
647 GLL 0.8657
648 3HM 0.8656
649 NNO 0.8656
650 FHB 0.8655
651 3HA 0.8654
652 XAN 0.8653
653 XUL 0.8652
654 2OP 0.8650
655 TZE 0.8647
656 6GU 0.8647
657 MFB 0.8646
658 I3A 0.8645
659 AZG 0.8645
660 LZM 0.8642
661 IGA 0.8637
662 CFP 0.8634
663 141 0.8634
664 KYD 0.8634
665 IHB 0.8633
666 5ZE 0.8633
667 6F0 0.8631
668 3M0 0.8630
669 ISZ 0.8629
670 QWN 0.8629
671 GLA 0.8627
672 MYJ 0.8627
673 290 0.8624
674 JZ4 0.8624
675 TSU 0.8620
676 MAN 0.8618
677 RB5 0.8612
678 PRY 0.8610
679 CHT 0.8610
680 F5B 0.8608
681 DPR 0.8605
682 3DO 0.8605
683 BR8 0.8605
684 PAV 0.8600
685 DMD 0.8600
686 40E 0.8600
687 2ZV 0.8593
688 COI 0.8592
689 V55 0.8592
690 51F 0.8591
691 1DQ 0.8590
692 GAB 0.8586
693 MET 0.8585
694 LDP 0.8585
695 B57 0.8584
696 4J8 0.8583
697 5Q0 0.8580
698 271 0.8580
699 MRZ 0.8578
700 JLZ 0.8575
701 3AB 0.8572
702 42A 0.8567
703 GRE 0.8566
704 THE 0.8565
705 WCE 0.8564
706 3NT 0.8560
707 1DV 0.8557
708 1SQ 0.8555
709 BHO 0.8554
710 FCR 0.8554
711 LRH 0.8550
712 4M4 0.8550
713 3HB 0.8548
714 OVV 0.8545
715 4WL 0.8542
716 ZZ3 0.8542
717 1P7 0.8540
718 NXA 0.8538
719 CFI 0.8535
720 4SD 0.8529
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4YRI; Ligand: 4JH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4yri.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 4YRI; Ligand: 4JH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4yri.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
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