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Receptor
PDB id Resolution Class Description Source Keywords
5AHO 2.16 Å EC: 3.1.-.- CRYSTAL STRUCTURE OF HUMAN 5' EXONUCLEASE APOLLO HOMO SAPIENS HYDROLASE DNA REPAIR METALLO-BETA-LACTAMASE DCLRE1B
Ref.: THE STRUCTURES OF THE SNM1A AND SNM1B/APOLLO NUCLEA DOMAINS REVEAL A POTENTIAL BASIS FOR THEIR DISTINCT PROCESSING ACTIVITIES. NUCLEIC ACIDS RES. V. 43 11047 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
EDO A:1316;
A:1315;
A:1317;
A:1314;
A:1318;
A:1323;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
ZN A:1321;
A:1320;
Part of Protein;
Part of Protein;
none;
none;
submit data
65.409 Zn [Zn+2...
TLA A:1319;
A:1322;
Valid;
Valid;
none;
none;
submit data
150.087 C4 H6 O6 [C@@H...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5AHO 2.16 Å EC: 3.1.-.- CRYSTAL STRUCTURE OF HUMAN 5' EXONUCLEASE APOLLO HOMO SAPIENS HYDROLASE DNA REPAIR METALLO-BETA-LACTAMASE DCLRE1B
Ref.: THE STRUCTURES OF THE SNM1A AND SNM1B/APOLLO NUCLEA DOMAINS REVEAL A POTENTIAL BASIS FOR THEIR DISTINCT PROCESSING ACTIVITIES. NUCLEIC ACIDS RES. V. 43 11047 2015
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 19 families.
1 5AHO - TLA C4 H6 O6 [C@@H]([C@....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 16 families.
1 5AHO - TLA C4 H6 O6 [C@@H]([C@....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 14 families.
1 5AHO - TLA C4 H6 O6 [C@@H]([C@....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: TLA; Similar ligands found: 13
No: Ligand ECFP6 Tc MDL keys Tc
1 TAR 1 1
2 TLA 1 1
3 SRT 1 1
4 RAT 0.588235 1
5 LGT 0.588235 1
6 GAE 0.588235 1
7 LAC 0.5 0.611111
8 2OP 0.5 0.611111
9 IPM 0.47619 0.8
10 LFC 0.434783 0.777778
11 ICT 0.416667 0.727273
12 DXX 0.411765 0.777778
13 MAK 0.4 0.941176
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5AHO; Ligand: TLA; Similar sites found with APoc: 1079
This union binding pocket(no: 1) in the query (biounit: 5aho.bio1) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 4JNA FAD None
2 1LSS NAD None
3 2BOS GLA GAL GLC None
4 3L8G GMB None
5 2BOS GLA GAL GLC NBU None
6 2W83 GTP None
7 1C4Q GLA GAL BGC None
8 3F8K COA None
9 4Z9D NAD None
10 4LPS GDP 0.826446
11 2DT5 NAD 0.947867
12 1U72 NDP 1.07527
13 1U72 MTX 1.07527
14 1JA9 NDP 1.09489
15 6F9Q NAD 1.10294
16 5XC5 GTP 1.13636
17 1GPE FAD 1.19048
18 4C4A SAH 1.19048
19 4UP3 NDP 1.27389
20 4QTU SAM 1.44231
21 3OZ2 FAD 1.4881
22 2Y6Q FAD 1.4881
23 2Y6Q I7T 1.4881
24 3GD4 NAD 1.4881
25 3GD4 FAD 1.4881
26 3SSO SAH 1.4881
27 5E72 SAM 1.4881
28 1R37 NAD 1.4881
29 5TUK FAD 1.4881
30 5H7K GDP 1.4881
31 3EC1 GDP 1.4881
32 2YYY NAP 1.4881
33 2O4C NAD 1.4881
34 1SC6 NAD 1.4881
35 4KOA NDP 1.5015
36 6BQ6 TER 1.51057
37 2HJR APR 1.52439
38 1GKZ ADP 1.54639
39 4XT8 TMQ 1.55039
40 4XT8 NAP 1.55039
41 5X20 NAD 1.60256
42 1HYH NAD 1.61812
43 3VYW SAM 1.62338
44 1Q7B NAP 1.63934
45 4B4U NAP 1.65016
46 5OJL TXP 1.67785
47 3MCT SAH 1.6835
48 1JQ3 AAT 1.68919
49 3B1F NAD 1.72414
50 2CVZ NDP 1.7301
51 1WP4 NDP 1.7301
52 2FCR FMN 1.7341
53 1L1E SAH 1.74216
54 2DPM SAM 1.76056
55 2NPX FAD 1.78571
56 2NPX NAD 1.78571
57 4CNK FAD 1.78571
58 4MOP 2H5 1.78571
59 4RPL FAD 1.78571
60 4RPL 3UC 1.78571
61 5JCM NAD 1.78571
62 5JCM ISD 1.78571
63 5JCM FAD 1.78571
64 4RVG TYD 1.78571
65 2VVL FAD 1.78571
66 2VVM FAD 1.78571
67 1RYI GOA 1.78571
68 2C7G FAD 1.78571
69 2C7G ODP 1.78571
70 3ICS FAD 1.78571
71 5VN0 NAI 1.78571
72 3ICR FAD 1.78571
73 1RYI FAD 1.78571
74 3AB1 FAD 1.78571
75 5VN0 FAD 1.78571
76 3ICT FAD 1.78571
77 5K8B PDG 1.78571
78 1I9G SAM 1.78571
79 4RVG SAM 1.78571
80 1G55 SAH 1.78571
81 1LLU NAD 1.78571
82 5DN9 NAD 1.78571
83 4P4T GDP 1.78571
84 1MOQ GLP 1.78571
85 1Z2A GDP 1.78571
86 2X5D PLP 1.78571
87 4BVA NDP 1.79104
88 3KB6 NAD 1.79641
89 1DSS NAD 1.8018
90 2RH4 EMO 1.80505
91 3LZW FAD 1.80723
92 3LZW NAP 1.80723
93 6GAS FAD 1.81269
94 5I7A 68Q 1.84049
95 3IA4 NDP 1.85185
96 1VL8 NAP 1.87266
97 3G6K POP 1.94805
98 3G6K FAD 1.94805
99 2P69 PLP 1.96078
100 5T2U NAP 2.01613
101 2AG5 NAD 2.03252
102 4EMI NAD 2.08333
103 4EMI FAD 2.08333
104 1D4D FAD 2.08333
105 1QO8 FAD 2.08333
106 2VHW NAI 2.08333
107 1RSG FAD 2.08333
108 1YY5 FAD 2.08333
109 1GET FAD 2.08333
110 1GET NAP 2.08333
111 5EZ7 FAD 2.08333
112 5TTJ FAD 2.08333
113 5BVA FAD 2.08333
114 3E1T FAD 2.08333
115 4USQ FAD 2.08333
116 5KOX RFP 2.08333
117 5KOX FAD 2.08333
118 4L8V NAP 2.08333
119 2ZJ1 ARJ 2.08333
120 2ZJ1 NAD 2.08333
121 3CIF NAD 2.08333
122 2V0C ANZ 2.08333
123 2DTX BMA 2.08333
124 1X87 NAD 2.08333
125 3CIF G3H 2.08333
126 4UCI SAM 2.08333
127 4PIV NDP 2.08333
128 2IZ1 ATR 2.08333
129 3L4S 3PG 2.08333
130 3L4S NAD 2.08333
131 3V1Y NAD 2.08333
132 4AMV F6R 2.08333
133 2Q1W NAD 2.1021
134 1J0X NAD 2.10843
135 5GWX SAR 2.11268
136 5GWX SAM 2.11268
137 5Y2W PGA 2.13675
138 2G37 FAD 2.14067
139 1U70 MTX 2.15054
140 1U70 NDP 2.15054
141 2F1K NAP 2.15054
142 1F3L SAH 2.18069
143 2HK9 NAP 2.18182
144 4I4Z 2NE 2.18182
145 1P77 ATR 2.20588
146 6ES0 BW8 2.2082
147 5N5D SAM 2.21239
148 6ECU SAH 2.21519
149 6ECW SAH 2.22222
150 1H2B NAJ 2.22841
151 1G2O IMH 2.23881
152 1RQL VSO 2.24719
153 2Q0L FAD 2.2508
154 3HAD NAD 2.27273
155 4YUW S4M 2.30263
156 4YUW 4JU 2.30263
157 5N6C NAD 2.33333
158 5GM1 SAH 2.3569
159 1XSE NDP 2.37288
160 3UOY NAP 2.38095
161 3UOY FAD 2.38095
162 4U8P UDP 2.38095
163 4U8P FDA 2.38095
164 4OPC FDA 2.38095
165 4OPC PGT 2.38095
166 4PLG NAI 2.38095
167 4PLG OXM 2.38095
168 3RNM FAD 2.38095
169 5J5Z FAD 2.38095
170 3HDY FAD 2.38095
171 2IVD FAD 2.38095
172 1SAY PYR 2.38095
173 3HDY GDU 2.38095
174 3HDY FDA 2.38095
175 1V59 FAD 2.38095
176 2RGJ FAD 2.38095
177 1Y8Q ATP 2.38095
178 5KMS NAD 2.38095
179 4K5S PM0 2.38095
180 4K5S FAD 2.38095
181 3LAD FAD 2.38095
182 1UWK URO 2.38095
183 1UWK NAD 2.38095
184 1GQ2 NAP 2.38095
185 1D1T NAD 2.38095
186 4XYB NDP 2.38095
187 3H9E NAD 2.38095
188 1IWE IMP 2.38095
189 2JB2 PHE 2.38095
190 2JB2 FAD 2.38095
191 1PL6 572 2.38095
192 1PL6 NAD 2.38095
193 2RCN GDP 2.38095
194 5KMS FAD 2.38095
195 1V59 NAD 2.38095
196 4NMC FAD 2.38095
197 4NMC 2OP 2.38095
198 1K3T BRZ 2.38095
199 4DCM SAM 2.38095
200 5A04 BGC 2.38095
201 5A04 NDP 2.38095
202 4EIP FAD 2.38095
203 1RF6 GPJ 2.38095
204 1RF6 S3P 2.38095
205 3GDN FAD 2.38095
206 5W75 GDP 2.38095
207 1KAO GDP 2.39521
208 4CE5 PDG 2.4024
209 1B63 ANP 2.4024
210 4IF4 BEF 2.40385
211 2GLX NDP 2.40964
212 4UUG PXG 2.40964
213 3LL5 ATP 2.40964
214 2NU8 COA 2.43056
215 1SOW NAD 2.43902
216 1KPG SAH 2.43902
217 1TPY SAH 2.43902
218 1KPH SAH 2.43902
219 6H1U ASP 2.43902
220 1NJR XYL 2.46479
221 4OXX FMN 2.46914
222 4POO SAM 2.5
223 3RG9 WRA 2.5
224 3RG9 NDP 2.5
225 1A5Z NAD 2.50784
226 1LTH NAD 2.50784
227 1LDN NAD 2.53165
228 4K26 SFF 2.53623
229 4K26 NDP 2.53623
230 5EO8 TFU 2.57235
231 4OM8 NAD 2.589
232 3IX9 NDP 2.63158
233 6EGU 43Y 2.63653
234 4KWI 1TJ 2.6616
235 4KWI NAP 2.6616
236 5TH5 MET 2.6616
237 1ZEM NAD 2.67176
238 3G2O SAM 2.67559
239 3T31 DCQ 2.67857
240 3T31 FAD 2.67857
241 6GAR FAD 2.67857
242 1XHC FAD 2.67857
243 6AIN FAD 2.67857
244 1YKJ FAD 2.67857
245 1YKJ PHB 2.67857
246 3GMB FAD 2.67857
247 3KLJ FAD 2.67857
248 5BRT FAD 2.67857
249 5BRT CH9 2.67857
250 1MO9 FAD 2.67857
251 1MO9 KPC 2.67857
252 1YQZ FAD 2.67857
253 1MV8 NAD 2.67857
254 2R4J FAD 2.67857
255 2R4J 13P 2.67857
256 6F3M NAD 2.67857
257 3NYC FAD 2.67857
258 3NYC IAR 2.67857
259 6F3N ADN 2.67857
260 6F3N NAD 2.67857
261 5JWC FAD 2.67857
262 5HXI FAD 2.67857
263 2A8X FAD 2.67857
264 2NVK FAD 2.67857
265 1G7S GDP 2.67857
266 2JHF NAD 2.67857
267 1GPM CIT 2.67857
268 2YX1 SFG 2.67857
269 1MUU NAD 2.67857
270 3TLJ SAH 2.67857
271 1U3U BNF 2.67857
272 1U3U NAD 2.67857
273 5HXI 5HN 2.67857
274 3DMH SAM 2.67857
275 3DMH GMP 2.67857
276 4ZEV M6P 2.67857
277 3AB3 GDP 2.67857
278 1QF5 GDP 2.67857
279 1QF5 RPL 2.67857
280 4D0N GDP 2.7027
281 4PLT OXM 2.71903
282 4PLT NAI 2.71903
283 6B92 SAH 2.72109
284 2EFE GNH 2.76243
285 2Q7V FAD 2.76923
286 3H4V NAP 2.77778
287 3H4V DVP 2.77778
288 5UAV NDP 2.79503
289 5UAV TFB 2.79503
290 1OTH PAO 2.80374
291 1WG8 SAM 2.80702
292 1ZQ9 SAM 2.80702
293 4RL4 PPV 2.83019
294 2G5C NAD 2.84698
295 5Z2L NDP 2.85714
296 5M42 FMN 2.86738
297 2BD0 NAP 2.86885
298 1DCP HBI 2.88462
299 5KKA 6V0 2.88462
300 4R81 FMN 2.91262
301 1KYQ NAD 2.91971
302 5EE5 GTP 2.92398
303 1QRD FAD 2.9304
304 1HSL HIS 2.94118
305 5T9F TYR 2.95203
306 5T9F NAP 2.95203
307 5T9E NAP 2.95203
308 3Q85 GNP 2.95858
309 2A8Y MTA 2.96296
310 4ZCC FAD 2.97619
311 4ZCC NAI 2.97619
312 5TWB FAD 2.97619
313 4IV9 FAD 2.97619
314 4JDR FAD 2.97619
315 2E5V FAD 2.97619
316 2QA1 FAD 2.97619
317 2RAB NAD 2.97619
318 2RAB FAD 2.97619
319 3AXB FAD 2.97619
320 3AXB PRO 2.97619
321 5X68 FAD 2.97619
322 4EDF UPG 2.97619
323 2HQM FAD 2.97619
324 4DP3 NDP 2.97619
325 4DP3 MMV 2.97619
326 5TS5 FAD 2.97619
327 4XQC 13D 2.97619
328 4XQC NAD 2.97619
329 3VC3 C6P 2.97619
330 5DX8 SFG 2.97619
331 5DWQ SFG 2.97619
332 4Z24 FAD 2.97619
333 2IXB A2G 2.97619
334 2IXB NAD 2.97619
335 6ARJ BW4 2.97619
336 6ARJ SAH 2.97619
337 2GN4 NDP 2.97619
338 2GN4 UD1 2.97619
339 4AT0 FAD 2.97619
340 4GCZ ADP 2.97619
341 2WET FAD 2.97619
342 2PTR 2SA 2.97619
343 2CDC NAP 2.97619
344 2POC BG6 2.97619
345 2CDC XYP 2.97619
346 2CDC XYS 2.97619
347 3JZ4 NAP 2.97619
348 1D1G NDP 2.97619
349 5DX0 SFG 2.97619
350 5IWQ PLP 2.99539
351 1J49 NAD 3.003
352 1J3I WRA 3.04878
353 1J3I NDP 3.04878
354 1XNK XS2 3.06122
355 2RBK VN4 3.06513
356 3DFR NDP 3.08642
357 4YAG NAI 3.11419
358 3OA2 NAD 3.14465
359 5UR0 NAD 3.15186
360 4U0I 0LI 3.1746
361 6GFK SAH 3.18725
362 3G89 SAM 3.21285
363 3WG6 NDP 3.25733
364 5XVH NAP 3.26797
365 1DLJ NAI 3.27381
366 3NDJ SAH 3.27381
367 3NDJ JHZ 3.27381
368 4REP FAD 3.27381
369 2B9W FAD 3.27381
370 1DLJ UGA 3.27381
371 1KNR FAD 3.27381
372 3NRR D16 3.27381
373 2YG3 FAD 3.27381
374 1KOL NAD 3.27381
375 3NRR NAP 3.27381
376 2HNK SAH 3.27381
377 1C0I BE2 3.27381
378 1C0I FAD 3.27381
379 5U19 SAH 3.27381
380 5U19 827 3.27381
381 4M52 FAD 3.27381
382 5KOK SAH 3.27381
383 5O9F 9ON 3.27381
384 5O9F NAD 3.27381
385 5OC1 FAD 3.27381
386 1E3I CXF 3.27381
387 1VJT NAD 3.27381
388 3PT9 SAH 3.27381
389 1P9B GDP 3.27381
390 3C6K MTA 3.27381
391 3C6K SPD 3.27381
392 5ZBC FAD 3.27381
393 5KVS NAP 3.27381
394 5N0J FAD 3.27381
395 5C9P FUC 3.27381
396 2C78 GNP 3.27381
397 3QV1 NAD 3.27381
398 3T34 GDP 3.27381
399 4ZUL UN1 3.27381
400 6CEP NAD 3.29341
401 1PZG A3D 3.32326
402 3Q3C NAD 3.34448
403 2BL9 NDP 3.36134
404 2BL9 CP6 3.36134
405 2ZIF SAM 3.367
406 3EGI ADP 3.39806
407 3C2O NTM 3.40136
408 4PIO SAH 3.40557
409 4PIO AVI 3.40557
410 3BGD SAH 3.46154
411 3BGD PM6 3.46154
412 1P0F NAP 3.48525
413 2X3F APC 3.50877
414 1P1C SAH 3.51759
415 1F6B GDP 3.53535
416 1FL2 FAD 3.54839
417 5LU5 M7P 3.5533
418 1J5P NAD 3.55731
419 1UXG NAD 3.55987
420 1UXG FUM 3.55987
421 4J36 1HR 3.57143
422 4J36 FAD 3.57143
423 5YB7 ORN 3.57143
424 5YB7 FAD 3.57143
425 4TM3 FAD 3.57143
426 1GTE FAD 3.57143
427 2EJU SAH 3.57143
428 3DPC HIS ALA TPO PRO PRO LYS LYS GLU ALA ASP 3.57143
429 3FG2 FAD 3.57143
430 3NTA FAD 3.57143
431 1YQD NAP 3.57143
432 1X7D ORN 3.57143
433 2FFU UDP 3.57143
434 1X7D NAD 3.57143
435 5X5U NAD 3.57143
436 1D8T GDP 3.57143
437 2BVN GNP 3.57143
438 5NDF LU2 3.57143
439 1ZXM ANP 3.57143
440 5NDF UDP 3.57143
441 5L13 6ZE 3.57143
442 5I34 GDP 3.57143
443 1KK1 GNP 3.57143
444 3U6K GDP 3.57143
445 3U6B GDP 3.57143
446 3H2B SAH 3.57143
447 5N5S NAP 3.57143
448 4J0Q GDP 3.57143
449 5FG3 GDP 3.57143
450 1V7C HEY 3.57143
451 6FNU FAD 3.57143
452 4KIB SAH 3.57143
453 1WDI CIT 3.57143
454 3WN0 FUB 3.57143
455 2HCJ GDP 3.58209
456 3HVJ 705 3.61991
457 1RE0 GDP 3.61991
458 1WMA NDP 3.62319
459 1WMA AB3 3.62319
460 1NW4 IMH 3.62319
461 4UME KDO 3.62694
462 5K0A FAD 3.63636
463 1L3I SAH 3.64583
464 1QX4 FAD 3.64964
465 3COW 52H 3.65448
466 3FPZ AHZ 3.68098
467 1LVL NAD 3.71179
468 1LVL FAD 3.71179
469 4TQG NDP 3.71517
470 2OYS FMN 3.71901
471 5GT9 NAP 3.80228
472 4OSP NAP 3.80228
473 5HRA DAS 3.82979
474 3QUR ADP 3.84615
475 3QUR FM4 3.84615
476 4NON GDP 3.84615
477 3IHG FAD 3.86905
478 4MO2 FDA 3.86905
479 1NAA 6FA 3.86905
480 1NAA ABL 3.86905
481 4MO2 FAD 3.86905
482 5FJN BE2 3.86905
483 5FJN FAD 3.86905
484 4YT4 FE9 3.86905
485 1U8X NAD 3.86905
486 5Z21 NAI 3.86905
487 6C4N NAP 3.86905
488 1VKO NAD 3.86905
489 4MP8 MLI 3.86905
490 4MP8 NAD 3.86905
491 4TMZ GSP 3.86905
492 3ETG GTP 3.86905
493 3ETG NDP 3.86905
494 3ETG GLU 3.86905
495 4UOX PLP PUT 3.86905
496 4W6Z 8ID 3.86905
497 4NCN GTP 3.86905
498 4MIG G3F 3.86905
499 4G5H NAP 3.86905
500 4G5H UD7 3.86905
501 2XTZ GSP 3.86905
502 2ZJ3 G6P 3.86905
503 5AOV NAP 3.86905
504 2PQB GG9 3.86905
505 6F5W KG1 3.86905
506 2BZG SAH 3.87931
507 3X44 PUS 3.91566
508 1KSH GDP 3.94737
509 3EWP APR 3.9548
510 5JE8 NAD 3.97351
511 4WOP CTP 4
512 5W7Q GDP 4.02145
513 3DUW SAH 4.03587
514 1T26 NAI 4.03727
515 1T26 GBD 4.03727
516 1OMO NAD 4.03727
517 5THQ NDP 4.04412
518 5Y8L NAD 4.0678
519 5Y8L HUI 4.0678
520 4EA7 JB2 4.09091
521 4EA7 COA 4.09091
522 1DL5 SAH 4.10095
523 2Z3Y F2N 4.16667
524 5DF1 NAP 4.16667
525 5DF1 58X 4.16667
526 1COY FAD 4.16667
527 1BZL FAD 4.16667
528 1BZL GCG 4.16667
529 3GFB NAD 4.16667
530 1V8B NAD 4.16667
531 4BJZ P3A 4.16667
532 4BJZ FAD 4.16667
533 3NJ4 NAD 4.16667
534 3NJ4 AFX 4.16667
535 6GNA FAD 4.16667
536 1COY AND 4.16667
537 1R6T TYM 4.16667
538 5Z20 NAI 4.16667
539 2RGH FAD 4.16667
540 4Z87 5GP 4.16667
541 4K47 WMP 4.16667
542 5ULJ 0WD 4.16667
543 4XB2 HSE 4.16667
544 5YT0 GDP 4.16667
545 4XB2 NDP 4.16667
546 1D2E GDP 4.16667
547 1KOJ PAN 4.16667
548 2JHP SAH 4.16667
549 4NTC FAD 4.1791
550 3VPH NAD 4.19355
551 3VPH OXM 4.19355
552 1LAF ARG 4.20168
553 1O3Y GTP 4.21687
554 4HK8 XYP XYP XYP XYP XYP XYP 4.2328
555 1JG3 ADN 4.25532
556 5D85 P1T 4.29448
557 1W73 NAP 4.30464
558 1W8D NAP 4.30464
559 5ZZ6 NAD 4.32692
560 5ZZ6 ADP 4.32692
561 5D9X GSH 4.34783
562 3JSX FAD 4.3956
563 3JSX CC2 4.3956
564 2B3D FAD 4.41176
565 4ITH RCM 4.42177
566 2BOI MFU 4.42478
567 3GGO ENO 4.4586
568 3GGO NAI 4.4586
569 4USR FAD 4.46429
570 3X0V FAD 4.46429
571 1Q1R FAD 4.46429
572 2RGO FAD 4.46429
573 3S5W FAD 4.46429
574 2XVF FAD 4.46429
575 1TQ4 GDP 4.46429
576 1WDK NAD 4.46429
577 1CDO NAD 4.46429
578 1T90 NAD 4.46429
579 4KM2 TOP 4.46927
580 4KM2 ATR 4.46927
581 1IM8 SAI 4.5082
582 3A1C ACP 4.52962
583 1FQK GDP 4.61538
584 6CI9 NAP 4.6332
585 6AA8 NAD 4.63576
586 3AFN NAP 4.65116
587 2P0D I3P 4.65116
588 2PWY SAH 4.65116
589 2GJ8 ALF GDP 4.65116
590 2VT3 ATP 4.65116
591 4YRY FAD 4.71014
592 4YRY NAD 4.71014
593 2B4Q NAP 4.71014
594 4NDO ATP 4.71014
595 4FE3 U5P 4.7138
596 3UCL NAP 4.7619
597 3UCL CYH 4.7619
598 3UCL FAD 4.7619
599 1E1M FAD 4.7619
600 1E1M NAP 4.7619
601 4DSG FAD 4.7619
602 4DSG UDP 4.7619
603 5MBX FAD 4.7619
604 5MBX SP5 4.7619
605 1L7E NAI 4.7619
606 2XVE FAD 4.7619
607 6F97 FAD 4.7619
608 3ZNN FAD 4.7619
609 3ZNN 4WL 4.7619
610 1FEC FAD 4.7619
611 5IE3 OXD 4.7619
612 5IE3 AMP 4.7619
613 1N1G BCP 4.7619
614 5M04 GDP 4.7619
615 2VTD LKM 4.7619
616 4Z0H NAD 4.79042
617 4NBU NAI 4.8
618 4IWN GEK 4.80349
619 1NVM NAD 4.80769
620 3QWI NAP 4.81482
621 3QWI CUE 4.81482
622 2WJH GDP 4.81928
623 2WJH FLC 4.81928
624 1N62 MCN 4.81928
625 5D4V SAH 4.85075
626 3JQF NAP 4.86111
627 1TE2 PGA 4.86726
628 2HF9 GSP 4.86726
629 4P3Y GDP 4.94506
630 1K27 MTM 4.947
631 4PC3 GDP 4.96454
632 2W9S NDP 4.96894
633 3GDH SAH 4.97925
634 5Z49 RUB 5.02092
635 2CIG 1DG 5.03145
636 4ZOH MCN 5.03597
637 4XUC SAM 5.04587
638 4XUC 43G 5.04587
639 4TXI FAD 5.05952
640 3OJO NAD 5.05952
641 3CGD NAD 5.05952
642 2BRY FAD 5.05952
643 2YVF FAD 5.05952
644 2YVF NAD 5.05952
645 3CGD FAD 5.05952
646 4HA6 FAD 5.05952
647 3CGD COA 5.05952
648 4YNU LGC 5.05952
649 4YNU FAD 5.05952
650 5EOW FAD 5.05952
651 4YDD MD1 5.05952
652 4YDD MGD 5.05952
653 1ME8 RVP 5.05952
654 4JJF FE9 5.05952
655 4JJF N2I 5.05952
656 3X0D SAH 5.05952
657 1F8G NAD 5.05952
658 1GZ4 ATP 5.05952
659 1E8G FCR 5.05952
660 6D6Y SAH 5.05952
661 1E5Q NDP 5.05952
662 2E7Z MGD 5.05952
663 3GRU AMP 5.08475
664 2IVF MD1 5.14019
665 2IVF MGD 5.14019
666 5MIT NAP 5.19878
667 5MIT FAD 5.19878
668 1L7N ALF 5.21327
669 1L7P SEP 5.21327
670 2VZ0 D64 5.22388
671 2VZ0 NAP 5.22388
672 4K81 GTP 5.26316
673 1RP0 AHZ 5.28169
674 1DR1 NAP 5.29101
675 1DR1 HBI 5.29101
676 6ECT SAM 5.29595
677 2PT9 S4M 5.29595
678 2PT9 2MH 5.29595
679 1HKU NAD 5.30726
680 1UQX MMA 5.30973
681 1YP4 ADP 5.32151
682 1PN0 FAD 5.35714
683 1PN0 IPH 5.35714
684 4C3Y FAD 5.35714
685 4C3Y ANB 5.35714
686 3KJS DQ1 5.35714
687 3KJS NAP 5.35714
688 5KVA SAM 5.35714
689 2B5W NAP 5.35714
690 1L5J TRA 5.35714
691 6AMI TRP 5.35714
692 6B0K 9RN G4S 9RN G4S 5.35714
693 1H6C NDP 5.35714
694 1QZR ANP 5.35714
695 1RYD NDP 5.35714
696 6B0K G4S 9RN G4S 9RN G4S 5.35714
697 1DAR GDP 5.35714
698 5E95 GDP 5.35714
699 5XNC MTA 5.35714
700 5HCN GCP 5.36398
701 2H9E DTY ILE ARG LEU LPD 5.36913
702 6D5V GNP 5.38922
703 2OFV 242 5.41516
704 4ZVV GN0 5.42169
705 9LDB NAD 5.42169
706 9LDT NAD 5.42169
707 4ZVV NAD 5.42169
708 1CLU DBG 5.42169
709 5O42 9JW 5.47445
710 5O42 BGC 5.47445
711 5O42 NAD 5.47445
712 3E70 GDP 5.4878
713 3T5G GDP 5.52486
714 1NYT NAP 5.53506
715 3BMN NAP 5.55556
716 5K6A NAP 5.55556
717 3JQB NAP 5.55556
718 4CM9 NAP 5.55556
719 3BMQ NAP 5.55556
720 3JQ8 NAP 5.55556
721 3JQ9 NAP 5.55556
722 4CME NAP 5.55556
723 4Y9D NAI 5.57377
724 2O07 SPD 5.59211
725 2O07 MTA 5.59211
726 1QH9 LAC 5.60345
727 4EMJ FAD 5.60748
728 6BSX E7S 5.61798
729 6BSX GDP 5.61798
730 1X1R GDP 5.61798
731 3AD8 NAD 5.65476
732 1I8T FAD 5.65476
733 4B63 ORN 5.65476
734 4B63 NAP 5.65476
735 4B63 FAD 5.65476
736 5I39 FAD 5.65476
737 1REO FAD 5.65476
738 2B4R NAD 5.65476
739 2B4R AES 5.65476
740 1C96 FLC 5.65476
741 1U1I NAD 5.65476
742 5HSA FAS 5.65476
743 5OCM NAP 5.65476
744 1ORR NAD 5.65476
745 6FDF SAH 5.68862
746 4E5N NAD 5.75758
747 5OJI NAP 5.76923
748 5OJI ISN 5.76923
749 4H6Q FAD 5.76923
750 4H6Q TFB 5.76923
751 6FA4 GNP 5.78035
752 1GUZ NAD 5.80645
753 1GV0 NAD 5.80645
754 4YMH SAH 5.83333
755 5O4J 9KH 5.83942
756 5O4J SAH 5.83942
757 5O4J PJL 5.83942
758 5FEU NAP 5.84192
759 1JP4 AMP 5.84416
760 3GJ5 GDP 5.88235
761 3GJ4 GDP 5.88235
762 3ICC NAP 5.88235
763 5L3W GDP 5.88235
764 2A92 NAI 5.919
765 2DC1 NAD 5.9322
766 3LL9 ADP 5.94796
767 6F7L FAD 5.95238
768 5TUF TDC 5.95238
769 5TUF FAD 5.95238
770 1PS9 FAD 5.95238
771 3CGB FAD 5.95238
772 5GSN FAD 5.95238
773 5GSN NAP 5.95238
774 5GSN MMZ 5.95238
775 2DFV NAD 5.95238
776 1UP7 NAD 5.95238
777 1ELI PYC 5.95238
778 1PS9 NAP 5.95238
779 3QVP FAD 5.95238
780 3EYA FAD 5.95238
781 3WGT FAD 5.95238
782 3WGT QSC 5.95238
783 5H7J GCP 5.95238
784 5MLR NAP 5.95238
785 5MLR GRQ 5.95238
786 3LCC SAH 5.95238
787 5BW4 SAM 5.99251
788 3FZG SAM 6
789 2Z9C DTC 6
790 2Z9C FMN 6
791 2I7C AAT 6.00707
792 3DOE GTP 6.06061
793 3T1O GDP 6.06061
794 1Q9I TEO 6.1296
795 1Q9I FAD 6.1296
796 4CQM NAP 6.13027
797 5YU3 PRO 6.25
798 5YU3 NAD 6.25
799 3NKS FAD 6.25
800 3NTD FAD 6.25
801 2HMT NAI 6.25
802 5CAE SIN 6.25
803 5CAE COA 6.25
804 3M6W SAM 6.25
805 2WR9 MAN MAN 6.25
806 1T9D FAD 6.25
807 5WKC FAD 6.25
808 4YKG FAD 6.25
809 2PZM NAD 6.36364
810 2PZM UDP 6.36364
811 5DLY SAH 6.39098
812 5DLY 5D7 6.39098
813 5WQP NCA 6.41026
814 5DXV NAP 6.41026
815 4JWJ SAH 6.43564
816 1P9P SAH 6.51341
817 4XZ3 COA 6.52174
818 3GJ8 GDP 6.52174
819 1X14 NAD 6.54762
820 5NMX FAD 6.54762
821 5NMX NAP 6.54762
822 1C1X NAD 6.54762
823 1BW9 NAD 6.54762
824 1BXG NAD 6.54762
825 4PL7 ATP 6.54762
826 3CTY FAD 6.58307
827 4LAE NAP 6.58683
828 4LAE 1VM 6.58683
829 4M9Q GNP 6.60793
830 5FFF 5XC 6.61479
831 5FFF NAP 6.61479
832 1W6U NAP 6.62252
833 3FUU ADN 6.64207
834 4OR7 NAP 6.66667
835 1BC5 SAH 6.69145
836 2NXE SAM 6.69291
837 1G0N NDP 6.71378
838 1G0N PHH 6.71378
839 4ZGS NAD 6.73575
840 3AKK ADP 6.76923
841 1S8F GDP 6.77966
842 6A4R ASP 6.79245
843 2DKH FAD 6.84524
844 2DKH 3HB 6.84524
845 5JCA NDP 6.84524
846 5JCA FAD 6.84524
847 2D7I UDP 6.84524
848 6EL3 NAP 6.84524
849 1G7C 5GP 6.84524
850 1ZC3 GNP 6.85714
851 1UAD GNP 6.85714
852 5F7J ADE 6.875
853 2CUL FAD 6.89655
854 3R96 AMP 6.91489
855 3R96 ACO 6.91489
856 3TKA SAM 6.91643
857 2DRC MTX 6.91824
858 2A0W DIH 6.92042
859 4X1Z FUC GAL NDG 6.92771
860 1SL3 170 6.96864
861 5XKT GNP 7
862 3FGZ BEF 7.03125
863 3MB5 SAM 7.05882
864 1RM4 NDP 7.12166
865 5ZYN FAD 7.14286
866 3AYI FAD 7.14286
867 3AYI HCI 7.14286
868 3L9W AMP 7.14286
869 3L9W GSH 7.14286
870 2FZW NAD 7.14286
871 6GNC FAD 7.14286
872 1U8Z GDP 7.14286
873 3VCY UD1 7.14286
874 1KYZ SAH 7.14286
875 1KYZ FER 7.14286
876 5ZCM NDP DTT 7.14286
877 4L2I NAD 7.22433
878 4L2I FAD 7.22433
879 4P3H 25G 7.25389
880 1Q0S SAH 7.33591
881 3DXY SAM 7.33945
882 4L6C 0BT 7.42574
883 1H82 GZZ 7.44048
884 1H82 FAD 7.44048
885 4M37 SAH 7.44048
886 4M38 SAH 7.44048
887 3VZ3 SSN 7.44048
888 3VZ3 NAP 7.44048
889 4FN4 NAD 7.48031
890 5L95 AMP 7.5
891 3SJU NDP 7.52688
892 5DI3 GNP 7.56757
893 2W2X GSP 7.56757
894 2QRY TPS 7.57576
895 2GAG NAD 7.61905
896 3GJ0 GDP 7.69231
897 3GJ3 GDP 7.69231
898 3QJ4 FAD 7.7381
899 3EF0 ALF 7.7381
900 1C3V NDP 7.7551
901 4AX9 N5N 7.7821
902 2FK8 SAM 7.86164
903 3CH5 GDP 7.87037
904 5FOM A2H 7.90378
905 5NNA BZM 7.95455
906 6BC0 GSP 8
907 2GV8 FAD 8.03571
908 1VQW FAD 8.03571
909 2GVC FAD 8.03571
910 2V6G NAP 8.03571
911 3LXD FAD 8.03571
912 2GV8 NDP 8.03571
913 2YN4 39J 8.05085
914 5NA1 FAD 8.08823
915 4JK3 NAD 8.10811
916 4J4H NAI 8.10811
917 4J4H 1J1 8.10811
918 5LOG SAH 8.15451
919 3GJ7 GDP 8.16327
920 3PQC GDP 8.20513
921 5T67 SAH 8.33333
922 5T67 JHZ 8.33333
923 6FP4 FAD 8.33333
924 6FP4 E1T 8.33333
925 1CF2 NAP 8.33333
926 5YEC ATP 8.33333
927 1O0S NAI 8.33333
928 1NM5 NAD 8.37438
929 5IDM ANP 8.37989
930 1GUA GNP 8.38323
931 5KUT GDP 8.46561
932 1VKF CIT 8.51064
933 5O96 SAM 8.57143
934 5Y77 FAD 8.63095
935 4D7E FAD 8.63095
936 4BV6 FAD 8.63095
937 5MZI FYK 8.63095
938 5MZI FAD 8.63095
939 1JNR FAD 8.63095
940 4RSL FAD 8.63095
941 4RQU NAD 8.63095
942 1TUU AMP 8.63095
943 4EIL NDP 8.92857
944 5U8U FAD 8.92857
945 5M67 3D1 8.92857
946 5M67 ADE 8.92857
947 2ZKJ ADP 8.92857
948 5M67 NAD 8.92857
949 3WY9 GDP 8.92857
950 3N26 ARG 8.94309
951 2JAR UMP 9
952 1EDO NAP 9.01639
953 4CNG SAH 9.01961
954 5O2T GSP 9.09091
955 4XYM COA 9.13043
956 3GF4 FAD 9.22619
957 3SQP FAD 9.22619
958 3GF4 UPG 9.22619
959 3OND ADN 9.22619
960 3OND NAD 9.22619
961 2CDU FAD 9.22619
962 1R27 MGD 9.22619
963 2CDU ADP 9.22619
964 1WK8 VMS 9.27835
965 2J0B UDP 9.28571
966 3FPF MTA 9.39597
967 3FPF TNA 9.39597
968 1GZ6 NAI 9.40439
969 2AG8 NAP 9.5057
970 2ZXI FAD 9.52381
971 4FWE FAD 9.52381
972 4GUT FAD 9.52381
973 4HSU FAD 9.52381
974 4GUS FAD 9.52381
975 2CWH NDP 9.52381
976 2CWH PYC 9.52381
977 2JDU MFU 9.56522
978 3A25 SAM 9.63455
979 5J60 FAD 9.6875
980 2OOR NAD 9.77011
981 5ZW3 SAH 9.77778
982 6FHO FAD 9.82143
983 3FWN ATR 9.82143
984 5ERG SAM 9.82143
985 4KP7 1UQ 9.82143
986 4KP7 NAP 9.82143
987 4BMO FMN 9.93789
988 1OBB NAD 10.119
989 5O74 GDP 10.1523
990 5ODQ FAD 10.3093
991 4H8N NDP 10.3226
992 5HPY GDP 10.3448
993 1GR0 NAD 10.4167
994 4BUY F37 10.4167
995 1JQD SAH 10.6164
996 4YSX FAD 10.7143
997 3SJ7 NDP 10.7143
998 5WS9 AMP 10.7143
999 2AJH MET 10.7143
1000 1AE1 NAP 10.989
1001 5NII FAD 11.0032
1002 4GKV NAD 11.0119
1003 1TMO 2MD 11.0119
1004 1G60 SAM 11.1538
1005 4X9M FAD 11.3095
1006 3QFA FAD 11.3095
1007 3A4T SFG 11.3139
1008 4ZI2 GNP 11.5789
1009 4GOJ GNP 11.6402
1010 4FZV SAM 11.7155
1011 4J3L AJ5 11.9048
1012 4FOU C2E 11.9658
1013 1NV8 MEQ 11.9718
1014 1NV8 SAM 11.9718
1015 1FZQ GDP 12.1547
1016 4NTD FAD 12.2024
1017 4II2 ATP 12.2699
1018 2FLI DX5 12.2727
1019 4D04 NAP 12.5
1020 4D04 FAD 12.5
1021 4RD0 GDP 12.5
1022 5UPK GNP 12.5
1023 2J59 GTP 12.5
1024 3RKR NAP 12.5954
1025 5BXQ GDP 12.5984
1026 2AE2 NAP 12.6923
1027 2AE2 PTO 12.6923
1028 1RM0 D6P 12.7976
1029 1RM0 NAI 12.7976
1030 3CBG SAH 12.931
1031 5L3V GDP 13.0435
1032 1DJN ADP 13.0952
1033 1O94 ADP 13.0952
1034 1O94 AMP 13.0952
1035 4J56 FAD 13.1579
1036 3OID NDP 13.1783
1037 1J2J GTP 13.3333
1038 3OCZ SRA 13.3588
1039 5G3U FDA 13.3929
1040 5G3U ITW 13.3929
1041 5BUK FAD 13.3929
1042 3RC1 TLO 13.6905
1043 3RC1 NAP 13.6905
1044 5WUW NAP 13.9373
1045 1TU3 GNP 14.0351
1046 1R2Q GNP 14.1176
1047 5HZX 2GE 14.2045
1048 5NWD 9C8 14.2857
1049 4RF2 NAP 14.3382
1050 4MRT COA 14.4444
1051 2YVJ NAI 14.6789
1052 2YVJ FAD 14.6789
1053 3K7M FAD 14.881
1054 1PVN MZP 14.881
1055 4M73 M72 15.1786
1056 4M73 SAH 15.1786
1057 3UC5 ATP 15.2866
1058 4M7V NAP 15.4286
1059 5OVK NDP 15.625
1060 6A3J NAI 15.8537
1061 6A3J SOE 15.8537
1062 4IAE 1DX 15.873
1063 3U4C NDP 16.0142
1064 5EPO NAP 16.0305
1065 2IID PHE 16.0714
1066 2IID FAD 16.0714
1067 3A27 SAM 16.5441
1068 3WLE NAD 17.3021
1069 3D36 ADP 17.3913
1070 1Z4O GL1 17.6471
1071 5ODT ADP 19.5652
1072 1R4A GNP 19.6078
1073 1L5Y BEF 20
1074 1E6E FAD 20.3125
1075 5OEC GDP 20.8122
1076 1LFD GNP 21.8391
1077 3WV8 ATP 22.0183
1078 5EIN NAP 24.0741
1079 2F5Z FAD 25
Pocket No.: 2; Query (leader) PDB : 5AHO; Ligand: TLA; Similar sites found with APoc: 57
This union binding pocket(no: 2) in the query (biounit: 5aho.bio1) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 6FYZ EBE 1.78571
2 1M2X MCO 1.79372
3 1GSA ADP 1.89873
4 3MAX LLX 2.08333
5 1C3R TSN 2.08333
6 3EPW JMQ 2.08333
7 6CR2 LFV 2.38095
8 5TXR PLP 2.38095
9 4N02 FNR 2.38095
10 2FNU PMP UD1 2.38095
11 4I71 AGV 2.42424
12 6CGZ HL6 2.48227
13 4OIV XX9 2.65487
14 6GXA TB8 2.67857
15 1JGT CMA 2.67857
16 3KFC 61X 2.7668
17 6B3A SAM 2.97619
18 5KD8 TNR 2.97619
19 6EW3 S3C 3.01724
20 5G0H E1Z 3.27381
21 2OGA PGU 3.27381
22 5HIP 61O 3.30033
23 2QDT I38 3.34572
24 5JPH COA 3.47222
25 5YAP NAI 3.57143
26 3LSJ COA PLM 3.63636
27 2V5X V5X 3.86905
28 4SLI CNP 4.16667
29 1WRA PC 4.22078
30 3VZS NAP 4.28016
31 3FRK TQP 4.46429
32 2VW1 DAN 4.46429
33 5G10 6DK 4.46429
34 3BXO SAM 4.60251
35 5D63 FUC GLA GLA 4.77816
36 1EFV FAD 5.09804
37 5U23 TQP 5.35714
38 4ZO3 C6L 5.44218
39 3A4X NAG NAG NAG NDG 5.46624
40 3IPQ 965 5.65371
41 3ZNR NU9 5.65476
42 2Z7I 742 5.95238
43 5TZJ UD1 5.95238
44 3FAL LO2 6.01504
45 4EXS X8Z 6.61765
46 2QE0 NAP 6.84524
47 1WUU ANP 7.14286
48 4ZAH T5K 7.7381
49 5W71 PLP 8.03571
50 5W71 9YM 8.03571
51 2P1E LAC