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Receptor
PDB id Resolution Class Description Source Keywords
5AV2 1.5 Å EC: 2.7.11.1 CRYSTAL STRUCTURE OF DAPK1-KAEMPFEROL COMPLEX IN THE PRESENC BROMIDE IONS. HOMO SAPIENS DEATH-ASSOCIATED PROTEIN KINASE 1 SERINE/THREONINE PROTEIN NATURAL FLAVONOID
Ref.: STRUCTURAL INSIGHT INTO THE INTERACTIONS BETWEEN DEATH-ASSOCIATED PROTEIN KINASE 1 AND NATURAL FLAVO J.MED.CHEM. V. 58 7400 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
BR A:307;
A:303;
A:301;
A:302;
A:306;
A:304;
A:305;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
submit data
79.904 Br [Br-]
KMP A:300;
Valid;
none;
submit data
286.236 C15 H10 O6 c1cc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2YAK 2.2 Å EC: 2.7.11.1 STRUCTURE OF DEATH-ASSOCIATED PROTEIN KINASE 1 (DAPK1) IN COMPLEX WITH A RUTHENIUM OCTASPORINE LIGAND (OSV) HOMO SAPIENS TRANSFERASE OCTAHEDRAL RUTHENIUM INHIBITORY COMPLEX KINASEINHIBITOR
Ref.: STRUCTURALLY SOPHISTICATED OCTAHEDRAL METAL COMPLEX HIGHLY SELECTIVE PROTEIN KINASE INHIBITORS. J.AM.CHEM.SOC. V. 133 5976 2011
Members (21)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 117 families.
1 1JKL - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 3F5G - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
3 5AUZ ic50 = 98 uM GEN C15 H10 O5 c1cc(ccc1C....
4 1P4F - DRG C12 H11 N3 c1ccc-2c(c....
5 4TXC Kd = 0.24 uM 38G C24 H27 N5 O3 CN(C)CCN[C....
6 2YAK ic50 = 2 nM OSV C27 H31 F N4 O3 Ru S4 CC(C)Oc1cc....
7 5AUY ic50 = 1.6 uM MRI C15 H10 O7 c1cc(c(cc1....
8 3EH9 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
9 1IG1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
10 5AUW ic50 = 8.9 uM QUE C15 H10 O7 c1cc(c(cc1....
11 5AV2 - KMP C15 H10 O6 c1cc(ccc1C....
12 5AUU ic50 = 21 uM LU2 C15 H10 O6 c1cc(c(cc1....
13 3EHA - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
14 5AV3 - KMP C15 H10 O6 c1cc(ccc1C....
15 5AUT Kd = 6.7 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
16 5AV0 ic50 = 280 uM 47X C15 H10 O5 c1cc(c(cc1....
17 1JKK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
18 3F5U - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
19 5AV4 - GEN C15 H10 O5 c1cc(ccc1C....
20 5AUX ic50 = 10 uM KMP C15 H10 O6 c1cc(ccc1C....
21 5AUV ic50 = 31 uM AGI C15 H10 O5 c1cc(ccc1C....
70% Homology Family (27)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 91 families.
1 1JKL - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 3F5G - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
3 5AUZ ic50 = 98 uM GEN C15 H10 O5 c1cc(ccc1C....
4 1P4F - DRG C12 H11 N3 c1ccc-2c(c....
5 4TXC Kd = 0.24 uM 38G C24 H27 N5 O3 CN(C)CCN[C....
6 2YAK ic50 = 2 nM OSV C27 H31 F N4 O3 Ru S4 CC(C)Oc1cc....
7 5AUY ic50 = 1.6 uM MRI C15 H10 O7 c1cc(c(cc1....
8 3EH9 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
9 1IG1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
10 5AUW ic50 = 8.9 uM QUE C15 H10 O7 c1cc(c(cc1....
11 5AV2 - KMP C15 H10 O6 c1cc(ccc1C....
12 5AUU ic50 = 21 uM LU2 C15 H10 O6 c1cc(c(cc1....
13 3EHA - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
14 5AV3 - KMP C15 H10 O6 c1cc(ccc1C....
15 5AUT Kd = 6.7 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
16 5AV0 ic50 = 280 uM 47X C15 H10 O5 c1cc(c(cc1....
17 1JKK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
18 3F5U - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
19 5AV4 - GEN C15 H10 O5 c1cc(ccc1C....
20 5AUX ic50 = 10 uM KMP C15 H10 O6 c1cc(ccc1C....
21 5AUV ic50 = 31 uM AGI C15 H10 O5 c1cc(ccc1C....
22 2YAB - AMP C10 H14 N5 O7 P c1nc(c2c(n....
23 2YAA - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
24 3BHY - 7CP C18 H18 Cl2 N4 O Cn1c2c(ccc....
25 2J90 - IZA C18 H16 F N3 O CC(C)(C)c1....
26 5VJA - DUK C14 H12 Cl N5 O2 S C[C@H](C(=....
27 5A6N ic50 = 2.1 uM U7E C7 H7 N5 O2 S c1cc(cc(c1....
50% Homology Family (420)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 3IGO - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 3NCG - BK1 C19 H19 N5 CC(C)n1c2c....
3 3MWU - BK3 C22 H24 N6 c1ccc2c(c1....
4 2XF0 ic50 = 30 uM 4UB C15 H11 N5 c1ccc(cc1)....
5 2YM6 ic50 = 0.88 uM YM6 C14 H16 N6 O c1cncc2c1c....
6 6FCK ic50 = 0.031 uM D4Z C20 H22 N4 O c1ccc(cc1)....
7 4QYG ic50 = 0.0041 uM 3DW C22 H21 N5 O2 CN1CCN(CC1....
8 3TKH ic50 = 47 nM 07S C23 H27 N7 O2 S c1cc(cnc1)....
9 2XEZ ic50 = 1.5 uM XEZ C12 H9 N7 c1c[nH]nc1....
10 2HXL ic50 = 12 nM 422 C23 H24 N6 c1cc2c(cc1....
11 5OQ7 ic50 = 0.8743 uM A0Q C24 H26 N4 O2 CN1CCN(CC1....
12 5F4N ic50 = 2.2 nM 5UY C17 H19 N7 O3 COC(=O)c1c....
13 2E9N ic50 = 6.2 nM 76A C29 H27 N3 O3 c1cc(ccc1c....
14 2YM3 ic50 = 1.2 uM YM3 C14 H19 N5 O3 CCOC(=O)c1....
15 2YDI - YDI C16 H20 N4 O3 S CN(C)CCOc1....
16 5OP5 ic50 = 0.4964 uM 3FE C17 H15 N5 O c1cc(cc(c1....
17 3NLB ic50 = 35 nM 5BE C21 H28 N6 O Cc1c(c([nH....
18 3JVR Ki = 1.89 uM AGX C16 H13 Cl2 N3 O2 C[C@@H](c1....
19 2WMX ic50 = 0.86 uM ZY6 C17 H19 N5 O c1ccc(cc1)....
20 2C3J Ki = 0.659 uM DBQ C11 H11 N5 O2 c1c[nH]c2c....
21 2YM7 ic50 = 0.13 uM YM7 C15 H18 N8 c1c(ncnc1N....
22 2X8I ic50 = 0.19 uM X8I C17 H13 N3 O2 CC1=CC2=NN....
23 2YDJ ic50 = 0.005 uM YDJ C17 H19 F N4 O2 S c1cc(cc(c1....
24 4QYE ic50 = 1.2 uM 3DL C17 H12 N2 O3 c1cc(cc(c1....
25 5OP7 - A1K C19 H21 Cl N6 O3 CNc1c2c(c[....
26 5OOP - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
27 5OPR ic50 = 5.8506 uM A3E C21 H26 N6 O CC(C)n1cc(....
28 2BRG ic50 = 6.1 uM DFY C21 H19 N3 O2 CN(CCO)c1c....
29 5OQ5 ic50 = 0.052 uM 4K4 C31 H38 N8 O3 CN1CCN(CC1....
30 2CGU ic50 = 13.4 uM 3A3 C17 H13 N O7 c1cc-2c(cc....
31 2WMR ic50 = 52 uM ZYR C10 H10 N2 O S C1CCc2c(c3....
32 3PA5 ic50 = 2 nM C73 C17 H19 Cl N4 O2 S c1cc(ccc1c....
33 2WMV ic50 = 9.2 uM ZYV C10 H14 N6 O c1[nH]c2c(....
34 5OQ8 ic50 = 4.0577 uM A0Q C24 H26 N4 O2 CN1CCN(CC1....
35 2CGX ic50 = 15.6 uM 3D3 C7 H8 N6 O S c1nc(c2c(n....
36 4QYF - 3DV C17 H13 N3 O3 c1cc(cc(c1....
37 5OPS ic50 = 1.9827 uM A3Q C14 H9 N3 O c1cc(cc(c1....
38 3JVS Ki = 0.146 uM AGY C22 H22 N4 O4 CC(C)(C)c1....
39 2WMW ic50 = 0.39 uM ZYW C11 H14 Br N5 O c1c2c(c(cn....
40 2BR1 Ki = 7.2 uM PFP C22 H21 N3 O4 COc1ccc(cc....
41 2C3L Ki = 0.026 uM IDZ C14 H10 N4 c1ccc2c(c1....
42 5OP2 ic50 = 0.5543 uM A0Q C24 H26 N4 O2 CN1CCN(CC1....
43 2X8E ic50 = 0.014 uM X8E C16 H12 N4 O CC1=CC2=NN....
44 2X8D ic50 = 0.8 uM X8D C11 H9 N3 O CC1=CC2=NN....
45 2YEX ic50 = 0.0001 uM YEX C15 H12 N4 O CC1=CC2=NN....
46 2BRM Ki = 1.3 uM DFZ C20 H18 N4 O c1ccc(cc1)....
47 1NVQ Ki = 5.6 nM UCN C28 H26 N4 O4 C[C@@]12[C....
48 5OOR - STU C28 H26 N4 O3 C[C@@]12[C....
49 3PA4 ic50 = 3 nM C72 C19 H19 Cl N4 O S c1cc(ccc1c....
50 4RVK ic50 = 13.5 nM 3XK C19 H13 N5 O CC(=O)Nc1c....
51 2HOG ic50 = 0.3 nM 710 C24 H25 N7 O c1cc2c(cc1....
52 6FC8 ic50 = 0.012 uM D4Q C19 H19 F N4 O S c1cc(cc(c1....
53 3LFN Ki = 3160 nM A27 C23 H21 N3 O2 CCCC(=O)Nc....
54 3PY1 Kd = 37 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
55 2A4L ic50 = 0.4 uM RRC C19 H26 N6 O CC[C@H](CO....
56 1Y8Y ic50 = 2 uM CT7 C13 H11 Cl N4 O2 S CS(=O)(=O)....
57 6GUH Kd = 26 nM FB8 C18 H21 N5 O2 S Cc1ncc(n1C....
58 1OIR ic50 = 0.032 uM HDY C23 H26 N6 O2 Cc1c(n2ccc....
59 1PXJ - CK2 C9 H10 N4 S Cc1c(sc(n1....
60 2VTO ic50 = 0.14 uM LZ8 C17 H13 F N4 O2 c1ccc(cc1)....
61 2BTR ic50 = 95 nM U73 C13 H15 N3 O S CC(C)C1=CN....
62 2VTA ic50 = 185 uM LZ1 C7 H6 N2 c1ccc2c(c1....
63 3EZR - EZR C26 H27 N7 O CN1CCN(CC1....
64 3ULI ic50 = 0.07 uM 1N3 C21 H25 Br N6 O2 COc1ccc(cc....
65 2DS1 ic50 = 6.4 nM 1CD C22 H21 N5 O3 C[C@@H]1C[....
66 5FP5 - 1Y6 C7 H5 F O2 c1cc(ccc1C....
67 2VTH ic50 = 120 uM LZ2 C10 H9 N O3 S c1cc2c(ccc....
68 1KE5 ic50 = 560 nM LS1 C16 H15 N3 O3 S CNS(=O)(=O....
69 3FZ1 - B98 C13 H15 N3 O2 S COc1ccc2c(....
70 1WCC ic50 = 350 uM CIG C4 H4 Cl N3 c1c(nc(cn1....
71 1PXO Ki = 2 nM CK7 C14 H12 N6 O2 S Cc1c(sc(n1....
72 1H00 ic50 = 38 uM FAP C21 H23 F2 N5 O2 CN(C)C[C@@....
73 2R3R - 6SC C18 H14 Br N5 c1ccc(cc1)....
74 1B39 Kd = 0.12 uM ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
75 3PXF Kd = 37 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
76 3TI1 - B49 C22 H27 F N4 O2 CCN(CC)CCN....
77 2R3G ic50 = 800 nM SC9 C18 H14 F N5 c1ccc(c(c1....
78 2C69 ic50 = 26 uM CT8 C17 H14 Br N6 c1cc(cc(c1....
79 2VTM ic50 ~ 1 mM LZM C7 H4 N4 c1cnc2c(cn....
80 4ERW - STU C28 H26 N4 O3 C[C@@]12[C....
81 1E1V Ki = 12 uM CMG C12 H17 N5 O c1[nH]c2c(....
82 2VV9 ic50 = 0.017 uM IM9 C23 H29 N7 O2 Cc1ncc(n1C....
83 5IEV - R0N C18 H23 F3 N4 O3 S C[C@H]([C@....
84 4D1X - ESJ C11 H8 N2 O3 S2 c1cc2c(cc1....
85 5MHQ - 8QT C19 H27 N7 O CC[C@@H]([....
86 2BTS ic50 = 20 nM U32 C12 H15 N3 O2 S2 CC(C)c1cnc....
87 1URW ic50 < 0.003 uM I1P C21 H24 N8 O2 S CN(C)CCCNS....
88 5FP6 - MFZ C11 H7 Cl2 N O c1cc(c2c(c....
89 1CKP - PVB C20 H25 Cl N6 O3 CC(C)[C@H]....
90 1KE6 ic50 = 5.7 nM LS2 C17 H15 N5 O3 S2 CNS(=O)(=O....
91 2C6K ic50 = 0.73 uM DT2 C17 H21 N7 O2 S c1cc(ccc1N....
92 2R3Q - 5SC C19 H16 Br N5 O Cc1ccccc1c....
93 1OIT ic50 < 0.003 uM HDT C17 H14 N6 O2 S c1ccn2c(c1....
94 3NS9 ic50 = 0.003 uM NS9 C20 H27 N5 O3 CC(C)c1cnn....
95 1H01 ic50 = 22 uM FAL C21 H23 Cl2 N5 O2 CN(C)C[C@H....
96 2EXM - ZIP C10 H13 N5 CC(=CCNc1c....
97 4BGH ic50 = 4 nM 3I6 C13 H16 Br N5 O3 S C[C@H](CO)....
98 2R3F ic50 = 500 nM SC8 C18 H13 Cl2 N5 c1cc(c(c(c....
99 1GII - 1PU C17 H16 N4 O2 c1ccnc(c1)....
100 2R64 ic50 = 0.03 uM 740 C23 H27 N5 O3 S c1cc(ccc1C....
101 5A14 - LQ5 C24 H26 F3 N7 O2 CN1CCN(CC1....
102 2C6L ic50 = 0.27 uM DT4 C17 H22 N8 O2 S c1cc(ccc1N....
103 2W06 - FRV C18 H20 N6 O2 S Cc1ncc(n1C....
104 4EZ7 - STU C28 H26 N4 O3 C[C@@]12[C....
105 5D1J ic50 = 48 nM 56H C17 H24 N4 O2 S2 CC(C)(C)c1....
106 5IEY - 6AE C14 H19 N5 O3 S C[C@H]([C@....
107 2VTT ic50 = 0.044 uM LZD C16 H17 F2 N5 O2 c1cc(c(c(c....
108 2VU3 ic50 = 0.047 uM LZE C16 H17 Cl2 N5 O2 c1cc(c(c(c....
109 2B54 - D05 C20 H15 Cl3 N4 O3 CCc1c2c(n(....
110 1GZ8 - MBP C10 H13 N5 O2 CC(C)C(=O)....
111 3PY0 ic50 = 0.13 uM SU9 C13 H11 N3 O2 COc1ccc2c(....
112 2VTR ic50 = 1.5 uM LZB C10 H10 Cl N5 CC(C)Nc1cc....
113 1E1X Ki = 1.3 uM NW1 C11 H17 N5 O2 C1CCC(CC1)....
114 3UNJ ic50 = 11 uM 0BX C17 H14 N4 O2 c1ccc(cc1)....
115 2A0C - CK9 C19 H26 N6 O2 CC[C@H](CO....
116 3TIY - TIY C11 H8 O5 c1c2c(c(c(....
117 2R3I ic50 = 1000 nM SCF C18 H14 F N5 c1ccc(c(c1....
118 1VYZ ic50 = 290 nM N5B C13 H13 N3 O c1ccc(cc1)....
119 3WBL ic50 = 23 uM PDY C20 H26 N6 O CCOc1ccc(c....
120 4RJ3 ic50 = 93 nM 3QS C22 H28 N6 O COC1CCN(CC....
121 2VTN ic50 = 0.85 uM LZ7 C12 H11 F N4 O2 CC(=O)Nc1c....
122 1AQ1 - STU C28 H26 N4 O3 C[C@@]12[C....
123 2C6M ic50 = 0.35 uM DT5 C17 H20 N6 O3 S c1cc(ccc1N....
124 2R3L ic50 = 100 nM SCW C18 H14 Br N5 c1ccc(cc1)....
125 1H08 - BYP BWP n/a n/a
126 1B38 Kd = 0.254 uM ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
127 2B52 ic50 = 8 nM D42 C21 H23 N7 O2 S Cc1c(sc(n1....
128 1PXL - CK4 C16 H13 F3 N4 S Cc1c(sc(n1....
129 3S2P ic50 = 0.068 uM PMU C17 H22 N4 O3 CC(C)c1cc(....
130 2R3O ic50 = 600 nM 2SC C19 H17 N5 O c1ccc(cc1)....
131 3IGG ic50 = 95 nM EFQ C16 H19 N3 O3 COc1ccc(cc....
132 1R78 ic50 = 3 nM FMD C20 H20 F N3 O4 C[C@H]([C@....
133 2FVD Ki = 0.003 uM LIA C18 H21 F2 N5 O4 S COc1ccc(c(....
134 2VTL ic50 = 97 uM LZ5 C10 H9 N3 O c1ccc(cc1)....
135 1KE9 ic50 = 660 nM LS5 C16 H15 N5 O3 S c1ccc2c(c1....
136 1PYE ic50 = 0.32 uM PM1 C21 H13 F2 N3 O2 c1ccc(cc1)....
137 4EZ3 - 0S0 C11 H10 N4 O4 S c1cc(ccc1/....
138 1H07 ic50 = 3 uM MFP C24 H27 Br N6 O2 Cc1ccc(c(c....
139 2B53 ic50 = 0.6 uM D23 C19 H19 F3 N4 CC(C)(C)Nc....
140 6GUK Kd = 725 nM FC8 C19 H24 Cl N7 CCn1cnc2c1....
141 2DUV ic50 = 0.087 uM 371 C19 H17 N O7 S Cc1cc2c(c(....
142 4D1Z - WG8 C13 H10 N2 O3 S c1cc2ccc(n....
143 4ACM Ki = 210 nM 7YG C20 H23 N7 O3 S CN(C)CCNS(....
144 2C5Y ic50 = 0.25 uM MTW C19 H15 N7 O2 c1cc(cc(c1....
145 2R3K ic50 = 100 nM SCQ C18 H14 Br N5 c1ccc(cc1)....
146 2V0D - C53 C9 H7 N3 O S [H]/N=C1/N....
147 2W1H ic50 = 0.052 uM L0F C17 H13 N5 O c1ccc(cc1)....
148 1Y91 ic50 = 0.059 uM CT9 C23 H33 N7 O2 S CC(C)c1cnn....
149 4FII - ARG PRO LYS PRO LEU VAL ASP PRO n/a n/a
150 4NJD ic50 = 0.79 uM NJD C21 H20 N8 O COc1nc(nc(....
151 4JDK - ARG ARG ARG ARG SER TRP TYR n/a n/a
152 5XVG Ki = 0.009 uM 8FX C20 H22 Cl N7 O C[C@@H]1CN....
153 2ZV2 - 609 C19 H10 N2 O3 c1ccc2c(c1....
154 4ONA ic50 = 0.002 uM UW1 C19 H23 N5 O2 CCOc1ccc2c....
155 4JBV ic50 = 0.003 uM V68 C26 H32 N6 O CC(C)COc1c....
156 3NYV - DTQ C16 H15 N3 O3 COc1cc2c(c....
157 3T3U Ki = 0.0025 uM BK6 C22 H24 N6 O COc1ccc2cc....
158 3KU2 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
159 4M84 ic50 = 0.049 uM 21E C17 H19 N5 O CC(C)(C)n1....
160 3HX4 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
161 3UPX Ki = 0.0075 uM B6A C20 H22 N4 O c1ccc(cc1)....
162 3SXF Ki = 0.0025 uM BK5 C20 H21 N5 O CCOc1ccc2c....
163 3T3V Ki = 0.003 uM BK4 C19 H19 N5 O CC(C)n1c2c....
164 3I7B ic50 = 0.066 uM BK1 C19 H19 N5 CC(C)n1c2c....
165 3V5P Ki = 0.011 uM C88 C19 H24 N6 O Cc1cc(ccc1....
166 3V51 - I76 C25 H22 Cl N5 O CC(C)n1c2c....
167 3UPZ - B5A C11 H16 N6 c1c2c(ncnc....
168 3I7C ic50 = 0.018 uM BK2 C19 H19 N5 CC(C)(C)n1....
169 3V5T - UW9 C24 H30 N6 O CCOc1ccc2c....
170 3N51 - BK3 C22 H24 N6 c1ccc2c(c1....
171 5OTO - AQW C24 H23 Cl2 N3 CCc1ccccc1....
172 3AT4 Kd = 2.26 nM CCK C20 H20 N6 O2 CC(C)Nc1cc....
173 3OWJ Ki = 0.86 uM 1EL C17 H14 N2 O2 Cc1c2c(c(c....
174 6EII - B5W C22 H23 Cl N c1ccc(cc1)....
175 5CU0 - 54R C18 H21 Cl N2 O CC(=O)NCCC....
176 5H8E ic50 < 0.003 uM 5Y3 C21 H25 N9 O CC(=O)Nc1c....
177 5OWH - B0K C10 H9 Br4 N3 c1nc2c(n1C....
178 3WAR - NIO C6 H5 N O2 c1cc(cnc1)....
179 5MOE Kd = 500 uM OQC C11 H10 Cl N O c1cc(c(cc1....
180 5OUE - AVZ C18 H19 Cl N3 c1ccc(cc1)....
181 5MOD Kd = 300 uM 86L C10 H14 Cl N O CC(C)Oc1cc....
182 5OWL - B0K C10 H9 Br4 N3 c1nc2c(n1C....
183 5CU3 Kd = 0.32 uM 54S C26 H26 Cl N3 O4 c1ccc(cc1)....
184 5OTR - AU8 C13 H12 Cl2 N c1ccc(cc1)....
185 4KWP Ki = 0.04 uM EXX C12 H10 Br4 N2 O3 c1nc2c(n1[....
186 5OSL - A9K C13 H12 Cl N O c1ccc(c(c1....
187 5N9N Ki = 0.4 nM KC5 C20 H15 Cl2 N O4 COc1ccc(cc....
188 5CSP Kd = 58 uM 54G C8 H8 O3 Cc1ccc(c(c....
189 5CTP - 54R C18 H21 Cl N2 O CC(=O)NCCC....
190 5MOW - BR9 C5 H6 Br N3 c1c(cnc(c1....
191 4UB7 Ki = 2.5 nM 3G5 C16 H8 Br2 O5 c1cc(ccc1C....
192 5MMF - JMB C16 H19 Cl N CCC[NH2+]C....
193 5OTH - AQ8 C25 H26 Cl N3 O CCc1ccccc1....
194 1PJK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
195 3NSZ - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
196 5OTI - AOK C25 H26 Cl N3 CCc1ccccc1....
197 3AXW - TID C9 H7 N3 O2 S c1cc(ccc1c....
198 5MO6 - KXZ C19 H21 Cl N2 O3 c1ccc(cc1)....
199 2PVR - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
200 3C13 - EMO C15 H10 O5 Cc1cc2c(c(....
201 5CS6 Kd = 630 uM K82 C10 H14 Cl N O CCCOc1ccc(....
202 3PE2 Ki = 0.175 nM E1B C20 H12 N4 O2 C#Cc1cccc(....
203 5CT0 - 54P C16 H18 Cl N O c1ccc(cc1)....
204 5CU6 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
205 5M4C - 7EY C16 H14 N2 O2 S2 Cc1ccc(cc1....
206 5MO7 - YRA C16 H17 Cl N2 O c1ccc(cc1)....
207 5N9L Ki = 15 nM 8QH C20 H15 Cl2 N O3 Cc1ccc(cc1....
208 5OT5 - AWK C25 H26 Cl N3 CCc1ccccc1....
209 3OWK ic50 = 1.5 uM 18E C16 H11 Cl N2 O Cc1cnc(c2c....
210 5MMR - H83 C17 H21 Cl N2 c1ccc(cc1)....
211 5MPJ - J2P C15 H17 Cl N CC[NH2+]Cc....
212 5OQU - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
213 6GIH - EZN C15 H13 Cl N2 c1cc(c2cc[....
214 5CSV - GAB C7 H7 N O2 c1cc(cc(c1....
215 5MOT - HBD C7 H7 N O2 c1cc(ccc1C....
216 3R0T ic50 = 0.91 nM FU9 C22 H16 F3 N5 O2 c1cc(cc(c1....
217 3PE1 Ki = 0.38 nM 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
218 3JUH - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
219 5CLP - 42J C8 H9 Cl2 N c1cc(c(cc1....
220 5ORH Kd = 41 uM A4N C14 H14 Cl N Cc1ccccc1c....
221 3H30 Ki = 29.2 uM RFZ C12 H12 Cl2 N2 O4 c1c2c(cc(c....
222 2ZJW ic50 = 0.04 uM REF C14 H6 O8 c1c2c-3c(c....
223 5OSZ - AHK C24 H25 Cl N3 CCc1ccccc1....
224 4GRB ic50 = 17 nM 0XG C19 H18 N4 O4 S CN(C)C(=O)....
225 5OT6 - AJK C19 H20 Cl N2 c1ccc(cc1)....
226 6EHK - AUW C24 H23 Cl2 N3 CCc1ccccc1....
227 3MB7 ic50 = 200 nM 14I C16 H8 O6 c1cc2c(cc(....
228 5OS8 - J27 C14 H14 Cl F N Cc1cc(ccc1....
229 5OTY - AUW C24 H23 Cl2 N3 CCc1ccccc1....
230 5OTD - AOW C24 H24 Cl N4 O2 CCc1ccccc1....
231 6GMD - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
232 5CVF - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
233 5CX9 - 551 C20 H23 Cl N2 O3 COC(=O)CC(....
234 5OUL - AWE C13 H11 Cl F N c1cc(cc(c1....
235 3SHE - I85 C24 H22 F3 N5 O2 c1cc(cc(c1....
236 5IZJ - 6J9 C10 H13 N5 c1c[nH]c2c....
237 3AG9 Ki = 9 nM A02 C40 H70 N18 O9 [H]/N=C(N)....
238 5IZF Kd = 1.7 nM 6J9 AZ1 DAR ACA DAR NH2 n/a n/a
239 2VZ6 - FEF C20 H19 N3 O4 c1ccc2c(c1....
240 2Z7R ic50 = 3 nM STU C28 H26 N4 O3 C[C@@]12[C....
241 4J8M ic50 = 48 nM CJ5 C26 H25 F3 N8 O c1cc(cc(c1....
242 5ORO - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
243 5OS4 Kd = 1665 uM A8H C14 H15 N O2 c1ccc(cc1)....
244 6HJJ ic50 = 1.7 uM G7T C26 H24 F4 N6 O2 Cc1cc(ccc1....
245 5ORS - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
246 5ORL - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
247 5DR9 - 5E2 C16 H9 Br Cl N O2 c1cc(cc(c1....
248 4DEA ic50 = 256 nM NHI C18 H14 N4 O4 c1cc(ccc1C....
249 5DN3 Kd = 3.77 uM 5DN C16 H9 Br F N O2 c1cc(cc(c1....
250 5ORP - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
251 4DEE - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
252 5OSE Kd = 681 uM A98 C6 H9 N3 O2 S2 CCSc1nnc(s....
253 5DNR - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
254 3UOD Kd = 49 nM 0C3 C18 H13 F3 N4 O2 c1ccc(c(c1....
255 3EFW - AK8 C25 H21 F3 N6 O2 Cc1cc(ccc1....
256 5DT0 - SKE C15 H12 F2 N6 O3 S c1cc(c(c(c....
257 3UO4 Kd = 299 nM 0C0 C23 H18 N4 O2 c1ccc(cc1)....
258 3UP2 Kd = 40 nM 0C8 C18 H13 F3 N4 O3 c1ccc(c(c1....
259 5ORX ic50 = 308 uM A6H C11 H8 Cl2 N2 O c1cc(c(c(c....
260 5ORN - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
261 5OS5 ic50 = 108 uM A8K C12 H10 O2 S c1cc(ccc1O....
262 5DR2 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
263 3DJ5 - AK5 C21 H20 Br N5 O3 S COc1ccc(cc....
264 3UOL ic50 = 3.1 nM 0C7 C17 H13 Cl N8 c1ccc(c(c1....
265 3D14 ic50 = 22 nM AK1 C19 H15 F3 N6 O S2 c1cc(cc(c1....
266 5OSD - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
267 5OS2 Kd = 1821 uM A7K C13 H21 N2 O c1ccc(c(c1....
268 4BN1 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
269 2NP8 ic50 = 42 nM CC3 C21 H18 F3 N5 O c1cc(cc(c1....
270 5ORR ic50 = 899 uM A5Q C9 H6 F3 N3 S c1cc(ccc1c....
271 4JBQ - VX6 C23 H28 N8 O S Cc1cc([nH]....
272 5OS3 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
273 5DRD - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
274 5DPV - SKE C15 H12 F2 N6 O3 S c1cc(c(c(c....
275 5ORZ ic50 = 245 uM A6W C10 H9 N O2 S2 COC(=O)c1c....
276 4UYN ic50 = 2 nM Y3M C25 H22 N4 O4 S CCOC(=O)c1....
277 5DT3 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
278 2WTV Ki = 1.8 nM ZZL C25 H15 Cl F2 N4 O2 c1cc(c(c(c....
279 6HJK ic50 = 25 nM G7W C25 H20 F4 N6 O2 CC(C)n1c2c....
280 3O50 - LJE C24 H17 F3 N4 O2 Cc1cc(ccc1....
281 2J4Z ic50 = 65 nM 626 C23 H24 N6 O2 S CN1CCN(CC1....
282 3LAU ic50 = 0.044 uM OFI C17 H17 N3 O2 CCCC(=O)Nc....
283 3DAJ ic50 = 2.9 uM FXG C22 H29 N7 O2 CCCCNC(=O)....
284 4JBO ic50 = 24 nM WPH C31 H32 N6 O3 CN(C)CCOc1....
285 5ORW Kd = 796 uM A6E C13 H16 F N O2 S c1cc(ccc1O....
286 2C6D - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
287 5OS0 Kd = 2792 uM A6Z C12 H15 Cl N3 c1cc(cc(c1....
288 3K5U ic50 = 309 nM PFQ C20 H17 N3 O2 c1ccc(cc1)....
289 4KS7 - X4Z C25 H28 N8 O S Cc1nc2ccsc....
290 4DGN ic50 = 0.35 uM LU2 C15 H10 O6 c1cc(c(cc1....
291 1M2Q - MNX C13 H7 N O6 c1cc(c2c(c....
292 2OXY - K17 C7 H2 Br4 N2 c1[nH]c2c(....
293 1M2R - MNY C14 H10 N2 O4 c1cc(c2c(c....
294 3KXN - K8X C7 H2 I4 N2 c1[nH]c2c(....
295 1ZOE Ki = 0.04 uM K25 C9 H7 Br4 N3 CN(C)c1[nH....
296 2PVL Ki = 0.024 uM P55 C18 H20 N8 CCN1CCN(CC....
297 1LP4 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
298 2PVN Ki = 0.00035 uM P63 C20 H16 N8 O CC(=O)Nc1c....
299 3KXG - K6X C7 H Br5 N2 c12c(c(c(c....
300 3BE9 Ki = 24 nM P04 C19 H21 N7 O c1cc2cc(c1....
301 2OXX - K22 C7 H2 Br4 N2 S c12c(c(c(c....
302 3KXM - K74 C11 H9 Br4 N3 O S CNC(=O)CSc....
303 1LR4 - BEN C7 H8 N2 [H]/N=C(c1....
304 1OM1 Ki = 0.17 uM IQA C17 H12 N2 O3 c1ccc2c(c1....
305 1ZOH Ki = 0.1 uM K44 C10 H7 Br4 N3 C[N@@]1CCn....
306 2PVK Ki = 0.008 uM P45 C19 H14 Cl N7 c1ccc(cc1)....
307 1DAY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
308 3EH9 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
309 1IG1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
310 5AUW ic50 = 8.9 uM QUE C15 H10 O7 c1cc(c(cc1....
311 5AV2 - KMP C15 H10 O6 c1cc(ccc1C....
312 5AUU ic50 = 21 uM LU2 C15 H10 O6 c1cc(c(cc1....
313 3EHA - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
314 5AV3 - KMP C15 H10 O6 c1cc(ccc1C....
315 5AUT Kd = 6.7 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
316 5AV0 ic50 = 280 uM 47X C15 H10 O5 c1cc(c(cc1....
317 1JKK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
318 3F5U - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
319 5AV4 - GEN C15 H10 O5 c1cc(ccc1C....
320 5AUX ic50 = 10 uM KMP C15 H10 O6 c1cc(ccc1C....
321 5AUV ic50 = 31 uM AGI C15 H10 O5 c1cc(ccc1C....
322 2XK6 - EQH C18 H21 N3 O2 S c1csc(c1C2....
323 2W5A - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
324 5M55 ic50 = 0.24 uM 7GG C17 H20 N6 CCN(CC)/C=....
325 2XNM ic50 = 0.16 uM WGZ C27 H27 F3 N4 O3 S C[C@H](c1c....
326 2XKF ic50 = 0.87 uM BX1 C19 H24 N4 O5 COc1cc(cc(....
327 2JAV ic50 ~ 8 uM 5Z5 C17 H16 Cl N3 O2 Cc1c([nH]c....
328 5M53 ic50 = 0.62 uM 7GJ C21 H26 N6 O2 CN(C)C(=O)....
329 2XK8 ic50 = 2.4 uM 5R1 C21 H21 N3 O6 COc1cc(ccc....
330 2WQO - VGK C21 H20 N2 O5 COc1cc(cc(....
331 2XKE ic50 = 4.2 uM WI2 C17 H20 N4 O3 COc1cccc(c....
332 2XNN - 430 C21 H16 F3 N3 O2 S C[C@H](c1c....
333 2XK7 ic50 = 1.5 uM 30E C21 H28 N4 O5 CC[C@H]1C[....
334 1Z5M ic50 = 30 nM LI8 C23 H31 Br N8 O3 CC(C)(C(=O....
335 5HKM ic50 = 0.013 uM 61Y C16 H15 N7 CCc1cc(nc(....
336 3QD0 ic50 = 0.00000001 M 3Q4 C24 H26 N8 O C[C@@H]1CC....
337 3ORZ - BI4 C27 H26 N4 O2 C[N@]1CCC[....
338 5LVN Kd = 20 uM ADN C10 H13 N5 O4 c1nc(c2c(n....
339 2XCH ic50 = 374 nM CKG C22 H25 N7 O c1c2c(nc(n....
340 4AW0 - MJF C18 H15 Cl O5 c1ccc(cc1)....
341 3OTU - BI4 C27 H26 N4 O2 C[N@]1CCC[....
342 3QCX ic50 = 0.00000001 M 3Q2 C16 H19 N7 O C[C@@H]1CO....
343 1UU3 ic50 = 0.75 uM LY4 C28 H28 N4 O3 CN(C)C[C@@....
344 5LVL Kd = 1.25 uM 537 C14 H8 N2 O c1ccc2c(c1....
345 3QC4 ic50 = 0.002 uM MP7 C28 H22 F2 N4 O4 c1ccc(cc1)....
346 3QCY ic50 = 0.00000001 M 3Q3 C22 H22 N8 O2 c1ccc(cc1)....
347 1UU8 ic50 = 9 uM BI1 C25 H24 N4 O2 CN(C)CCCn1....
348 4CT1 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
349 4A07 - AZ7 C17 H13 Cl3 N2 O2 c1cc(ccc1[....
350 2X39 ic50 = 30 nM X39 C19 H21 Cl N6 O c1cc(ccc1C....
351 3E87 - GLY ARG PRO ARG THR THR SER PHE ALA GLU n/a n/a
352 4QNA ic50 = 0.023 uM X11 C9 H9 N5 O c1ccc(c(c1....
353 4QMO ic50 = 0.019 uM 34L C13 H8 N4 O S c1cc2c(c3c....
354 4QMW ic50 = 0.086 uM KS1 C17 H17 N7 c1c[nH]c2c....
355 3A7H - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
356 4QML - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
357 4QO9 ic50 = 0.16 uM 627 C26 H30 N6 O3 CN1CCN(CC1....
358 4QMQ ic50 = 0.26 uM 34U C24 H27 N5 O2 COCCOc1ccc....
359 4EL9 - AFE C21 H20 O10 C[C@H]1[C@....
360 5D9L ic50 = 0.024 uM 583 C15 H12 N2 O2 c1cc(ccc1c....
361 2XK9 ic50 = 0.03 nM XK9 C18 H17 N7 O4 C/C(=NNC(=....
362 2YCS ic50 = 1.36 nM NXP C18 H18 N6 O C/C(=NNC(=....
363 2WTI ic50 = 0.092 uM WTI C18 H15 N3 O3 S c1cc(ccc1c....
364 2YIR ic50 = 0.17 nM YIR C20 H19 N7 O3 [H]/N=C(N)....
365 2XBJ ic50 = 0.86 uM XBJ C23 H27 F N4 O4 CC(C)([C@@....
366 2XM9 ic50 = 0.009 uM LWH C21 H20 N6 O c1ccc2c(c1....
367 2YIQ ic50 = 12.67 nM YIQ C20 H19 N7 O C/C(=NNC(=....
368 2CN5 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
369 3HZT - J60 C22 H27 Cl N4 O2 CCN(CC)CCN....
370 4FG8 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
371 5L2S - 6ZV C27 H32 F2 N8 CCN1CCN(CC....
372 4AUA ic50 = 7.2 uM 4AU C12 H9 N3 O c1ccc2c(c1....
373 5K00 ic50 = 7.1 nM 6PV C32 H34 N6 O4 COc1cccc(c....
374 5MAG - 7KC C25 H30 N8 O S Cc1nc2ccsc....
375 5IHC ic50 = 0.013 uM 6BB C20 H21 F N4 O c1ccc(c(c1....
376 6BUU - GLY ARG PRO ARG THR THR ZXW PHE ALA GLU n/a n/a
377 3QKM ic50 = 0.038 uM SM9 C31 H43 N5 O4 S CCOCCN(C[C....
378 3CQU ic50 = 151 nM CQU C15 H13 N7 Cc1[nH]c(n....
379 2WEI ic50 = 3.4 nM VGG C17 H21 N5 Cc1cccc(c1....
380 3C0G - 3AM C10 H14 N5 O7 P c1nc(c2c(n....
381 3MFR - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
382 4OTI ic50 = 43 nM MI1 C16 H20 N6 O C[C@@H]1CC....
383 3OFM - 4B0 C9 H7 Br4 N3 O C(Cn1c2c(c....
384 5YF9 - NIO C6 H5 N O2 c1cc(cnc1)....
385 5ONI - 9YE C23 H25 N O3 CC(C)n1c2c....
386 3WF7 ic50 = 206 nM FS9 C18 H17 F3 N6 O c1cc(cc(c1....
387 4L3J - 5FI C19 H21 F3 N6 CCc1cncnc1....
388 3WF6 ic50 = 33 nM FZ9 C18 H16 N6 c1ccc2c(c1....
389 4AU8 ic50 = 551 nM Z3R C11 H8 N2 O2 S3 c1ccc2c(c1....
390 6B16 Ki = 32 nM C7Y C19 H20 N8 C[C@@H](c1....
391 5DFP Ki = 22 nM 59U C28 H32 Cl N7 O CCN1c2c(cn....
392 3FXZ ic50 = 130 nM FLL C30 H18 Cl F N5 O4 Ru c1ccc(cc1)....
393 5IME Ki = 4.6 nM 6BZ C22 H22 Cl N7 O2 CC1=NC=CN(....
394 4ZY6 Ki = 5 nM 4T6 C18 H17 Cl N8 c1cc2c(c(c....
395 3Q53 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
396 4EQC ic50 = 0.008 uM XR1 C29 H28 Cl N7 O S CCN1c2c(cn....
397 5JZJ - AN2 C10 H16 N6 O9 P2 c1nc(c2c(n....
398 5AX9 ic50 = 8 nM 4KT C24 H24 N4 O3 COc1ccc(cc....
399 2J7T - 274 C28 H30 Cl N5 O4 S Cc1c([nH]c....
400 4JQE - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
401 4MWH - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
402 4LFI - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
403 3GGF - GVD C22 H19 N7 c1ccc2c(c1....
404 4U44 ic50 = 0.008 uM 3D9 C17 H13 N5 c1ccc(cc1)....
405 3DAK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
406 1QL6 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
407 1PHK - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
408 3M2W ic50 < 0.003 uM L8I C23 H21 F N4 O CN1CC2(C1)....
409 3BHY - 7CP C18 H18 Cl2 N4 O Cn1c2c(ccc....
410 2J90 - IZA C18 H16 F N3 O CC(C)(C)c1....
411 5VJA - DUK C14 H12 Cl N5 O2 S C[C@H](C(=....
412 5A6N ic50 = 2.1 uM U7E C7 H7 N5 O2 S c1cc(cc(c1....
413 6CMJ ic50 = 5 nM F6J C24 H22 N2 O2 CC(C)Cc1cc....
414 2VN9 - GVD C22 H19 N7 c1ccc2c(c1....
415 4EJN ic50 = 0.005 uM 0R4 C33 H26 F N7 O2 CC(=O)Nc1c....
416 4WNO ic50 = 160 nM 3RF C20 H19 N7 c1ccc2c(c1....
417 4WNP ic50 = 8 nM 3RJ C22 H20 N8 c1ccc2c(c1....
418 5CI7 ic50 = 120 nM 51W C18 H24 I N7 O c1cc(cc(c1....
419 2V7O - DRN C25 H23 N5 O2 S [H]/N=C(/N....
420 3AQV - TAK C24 H25 N5 O c1cc(ccc1c....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: KMP; Similar ligands found: 9
No: Ligand ECFP6 Tc MDL keys Tc
1 KMP 1 1
2 QUE 0.678571 0.967742
3 MYC 0.642857 0.967742
4 MRI 0.603448 1
5 CC6 0.532258 1
6 AFE 0.48 0.857143
7 AGI 0.444444 0.933333
8 GEN 0.4375 0.935484
9 SL0 0.418605 0.833333
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2YAK; Ligand: OSV; Similar sites found with APoc: 568
This union binding pocket(no: 1) in the query (biounit: 2yak.bio1) has 30 residues
No: Leader PDB Ligand Sequence Similarity
1 1RL4 BL5 None
2 6B79 ORA None
3 1RL4 BRR None
4 4JNJ BTN None
5 1NBU PH2 None
6 2CBO TH2 None
7 3EW2 BTN None
8 3KYF 5GP 5GP 0.865801
9 2ET1 GLV 0.995025
10 3NZ1 3NY 1.14943
11 4NAE 1GP 1.33333
12 2IF8 ADP 1.40351
13 1MJT ITU 1.40351
14 3ZXE PGZ 1.50376
15 1Q8Q MAN MMA 1.5873
16 3K5I ADP 1.75439
17 1F52 ADP 1.75439
18 3DNT ATP 1.75439
19 2V58 LZJ 1.75439
20 1SDW IYT 1.75439
21 2IVD ACJ 1.75439
22 5GLT BGC GAL NAG GAL 1.76056
23 3VPB ADP 1.77305
24 3VPC ADP 1.77305
25 6E8I PTR 1.77515
26 1ZNY GDP 1.93237
27 1F5F DHT 1.95122
28 3H7J PPY 2.05761
29 2YRX AMP 2.10526
30 4RDL FUC GAL NDG FUC 2.10526
31 4U98 ACP 2.10526
32 4OJ8 AKG 2.10526
33 4TVD BGC 2.10526
34 1OFL NGK GCD 2.10526
35 2QPU QPS 2.10526
36 4MIB 28M 2.10526
37 3IX1 NFM 2.10526
38 2QPU QPU 2.10526
39 4YRI 4JH 2.10526
40 2UXR ICT 2.10526
41 5L2R MLA 2.10526
42 4R38 RBF 2.14286
43 5NM7 GLY 2.25564
44 1KDK DHT 2.25989
45 2RDE C2E 2.39044
46 3ZJX BOG 2.45614
47 1RYD GLC 2.45614
48 4B0T ADP 2.45614
49 1GQG DCD 2.45614
50 1KKR 2AS 2.45614
51 5OLK DTP 2.45614
52 4RD0 GDP 2.45614
53 3T3Z 9PL 2.45614
54 5LUN OGA 2.45614
55 6APF CIT 2.4911
56 2QX0 PH2 2.51572
57 4H6B 10Y 2.5641
58 2PZE ATP 2.62009
59 1J3R 6PG 2.63158
60 3KYG 5GP 5GP 2.64317
61 2FUE M1P 2.67176
62 3SHR CMP 2.67559
63 1Y7P RIP 2.69058
64 4XMF HSM 2.71739
65 2VT3 ATP 2.7907
66 2PUL ACP 2.80702
67 3BP1 GUN 2.80702
68 5HV7 RBL 2.80702
69 3E7S AT2 2.80702
70 3GD9 GLC BGC BGC BGC 2.80702
71 3I0O ADP 2.80702
72 1PK8 ATP 2.80702
73 2XN3 ID8 2.80702
74 2Q8E OGA 2.80702
75 1AUX AGS 2.80702
76 3KAL ADP 2.80702
77 5Z46 8XL 2.80702
78 4CU1 71S 2.80702
79 3O2K DST 2.80702
80 4RF7 ARG 2.80702
81 4K37 SAM 2.80702
82 5VLQ ANP 2.80702
83 6FA4 D1W 2.89017
84 2TPI ILE VAL 3.05677
85 3VOT ADP 3.15789
86 2Z49 AMG 3.15789
87 3QSB 743 3.15789
88 5W75 SUC 3.15789
89 2Z48 A2G 3.15789
90 2Z48 NGA 3.15789
91 2IO8 ADP 3.15789
92 2GEK GDP 3.15789
93 4M00 SUC 3.15789
94 5A0U CHT 3.15789
95 2HGS ADP 3.15789
96 3I4X DST 3.15789
97 4IAW LIZ 3.19149
98 2BKX F6R 3.30579
99 5ML3 DL3 3.3557
100 2GQR ADP 3.37553
101 2QHS OCA 3.37553
102 5L4R CPT 3.38164
103 2HZQ STR 3.44828
104 1EB1 ASP TYR GLU PRO ILE PRO GLU GLU ALA PHE 3.50195
105 3OQJ 3CX 3.50195
106 6CGD GNP 3.50877
107 6CGD AKN 3.50877
108 2PYW ADP 3.50877
109 1GSA ADP 3.50877
110 1VRP ADP 3.50877
111 5ZCT ANP 3.50877
112 3V4S ATP 3.50877
113 1G51 AMP 3.50877
114 5IH1 GDP 3.50877
115 5IH1 6BQ 3.50877
116 5CKS GAL 3.50877
117 4BG4 ADP 3.50877
118 4QDC ASD 3.50877
119 4QCK ASD 3.50877
120 2NSX IFM 3.50877
121 3RGA LSB 3.53357
122 1IS3 LAT 3.7037
123 1CBK ROI 3.75
124 1GT4 UNA 3.77358
125 2QHV OC9 3.80952
126 5G48 1FL 3.85965
127 2CFM AMP 3.85965
128 3REU ATP 3.85965
129 5IGI GMP 3.85965
130 5IGI ZIT 3.85965
131 4FMS BDP 3.85965
132 2O0J ADP 3.85965
133 1ZTH ADP 3.87597
134 1ZP9 ATP 3.87597
135 2G30 ALA ALA PHE 3.87597
136 4Y24 TD2 3.8961
137 3QPB URA 3.90071
138 4XYM A12 3.91304
139 4XZ3 ACP 3.91304
140 5M37 9SZ 3.91304
141 6DW2 HD4 3.92157
142 1IA9 ANP 3.92857
143 4JLS 3ZE 3.94737
144 4YJK URA 3.96825
145 5EJL C2E 4.03226
146 4OCT AKG 4.05405
147 3E3U NVC 4.06091
148 5MW8 ATP 4.21053
149 4UWH JXM 4.21053
150 1EHI ADP 4.21053
151 4LH7 1X8 4.21053
152 5YJS SAL 4.21053
153 3TII ANP 4.21053
154 4FFG 0U8 4.21053
155 4NOS ITU 4.21053
156 4OYA 1VE 4.21053
157 4B1L FRU 4.24242
158 1MFI FHC 4.38596
159 3T4L ZEA 4.44444
160 3QRC SCR 4.4586
161 3OYW TDG 4.47761
162 1W6P NDG GAL 4.47761
163 5EZU MYR 4.49438
164 5VZ0 ADP 4.5614
165 2ZL7 FUC GAL NGA 4.5614
166 3G1Z AMP 4.5614
167 1ELI PYC 4.5614
168 1OBD ATP 4.5614
169 1KC7 PPR 4.5614
170 4YRD 3IT 4.5614
171 4X9X OLA 4.5614
172 5DXT 5H5 4.5614
173 5FXD H7Y 4.5614
174 2FB3 MET 4.5614
175 6FFK D7Z 4.57516
176 4KU7 PCG 4.57516
177 3VPD ANP 4.62633
178 5GZ9 ANP 4.91228
179 3CF6 SP1 4.91228
180 5KJW 53C 4.91228
181 5FPE 3TR 4.91228
182 4CJN QNZ 4.91228
183 5I49 2KH 4.91228
184 4PZ6 GMP 4.91228
185 2VQD AP2 4.91228
186 5H9Y BGC BGC BGC BGC 4.91228
187 1LSH PLD 4.91228
188 2Q7D ANP 4.91228
189 1DTL BEP 4.96894
190 3QH2 3NM 4.97738
191 5TV6 PML 5
192 3OCP CMP 5.03597
193 4NFE BEN 5.06329
194 1TZD ADP 5.09091
195 6FOF LAT 5.10204
196 4RYV ZEA 5.16129
197 3PNA CMP 5.19481
198 5C1P ADP 5.22876
199 1F9V ADP 5.26316
200 5IM3 DTP 5.26316
201 4PU5 ANP 5.26316
202 4GYI ADP 5.26316
203 4ZGP ADP 5.26316
204 3THR C2F 5.26316
205 2R09 4IP 5.26316
206 5LXT ACP 5.26316
207 3KC1 2T6 5.26316
208 2R0D 4IP 5.26316
209 4OUJ LBT 5.26316
210 3B6R ADP 5.26316
211 4KAX 4IP 5.32544
212 3WVR AMP 5.36913
213 3NBC LAT 5.40541
214 1QAW TRP 5.40541
215 4WUJ FMN 5.44218
216 3CBC DBS 5.55556
217 5V4R MGT 5.55556
218 4ZS4 ATP 5.61404
219 2Z3U CRR 5.61404
220 5TDF ADP 5.61404
221 3VSV XYS 5.61404
222 3VSV XYP 5.61404
223 3AB4 THR 5.61798
224 4C01 QY9 5.67376
225 1W8S FBP 5.70342
226 1ONI BEZ 5.7971
227 3PDT ADP 5.81818
228 3ZGJ RMN 5.96491
229 2OVW CBI 5.96491
230 2R5V HHH 5.96491
231 2XN2 GLA 5.96491
232 6EOM ALA LYS 5.96491
233 5N53 8NB 6.15385
234 2C94 TSF 6.25
235 4FE2 AIR 6.27451
236 4FE2 ADP 6.27451
237 3W0O ADP 6.31579
238 3W0O HY0 6.31579
239 5AE9 OKO 6.31579
240 1YFS ALA 6.31579
241 6EZ6 C5Z 6.31579
242 2VPQ ANP 6.31579
243 3WO0 ALA 6.31579
244 3WO0 ADP 6.31579
245 6C90 ADP 6.31579
246 1Z03 OCH 6.31579
247 5H9P TD2 6.32911
248 2GQS C2R 6.32911
249 2GQS ADP 6.32911
250 2XG5 EC2 6.42202
251 2XG5 EC5 6.42202
252 1UPR 4IP 6.50407
253 4O9S 2RY 6.51163
254 2XOC ADP 6.51341
255 5FU3 BGC BGC BGC 6.60377
256 5MRH Q9Z 6.66667
257 6FL8 ADP 6.66667
258 6FL8 TIY 6.66667
259 3UDZ ADP 6.66667
260 1ULE GLA GAL NAG 6.66667
261 5YK1 ANP 6.66667
262 2AQX ATP 6.66667
263 4LIT AKG 6.66667
264 6EAC ANP 6.66667
265 1CX4 CMP 6.66667
266 4YEE 4CQ 6.66667
267 4R29 SAM 6.69643
268 3GD8 GOL 6.72646
269 1W2D ADP 6.79245
270 1W2D 4IP 6.79245
271 4DOO DAO 6.82927
272 1P6O HPY 6.8323
273 2YKL NLD 6.94444
274 6CDO ALA VAL GLY ILE GLY ALA VAL PHE 6.95652
275 5C8W PCG 6.99301
276 5I0U DCY 7
277 1E4E ADP 7.01754
278 3HQP OXL 7.01754
279 4J6C STR 7.01754
280 5FI4 5XV 7.01754
281 6FXR AKG 7.01754
282 5E65 5N6 GAL 7.01754
283 2VDF OCT 7.11462
284 3DGY 2GP 7.2165
285 5ODY 9SK 7.24638
286 4OCJ NDG 7.36842
287 5DZT AMP 7.36842
288 6C1S EFV 7.36842
289 2GC0 PAN 7.44681
290 4Q5H ANP 7.47126
291 4OFG PCG 7.63889
292 5EQY 5RA 7.7193
293 4OCV ANP 7.7193
294 5T7I LAT NAG GAL 7.74194
295 4DYG MES 7.78689
296 2GOO NDG 7.89474
297 3NV3 GAL NAG MAN 7.97101
298 4DE2 DN3 7.98479
299 5AIG VPR 8
300 2W5P CL8 8.05369
301 3IWD M2T 8.06452
302 3JQ3 ADP 8.07018
303 1I7L ATP 8.07018
304 4D1J DGJ 8.07018
305 3P7N FMN 8.13953
306 5Y4R C2E 8.27586
307 2PR5 FMN 8.33333
308 4R78 AMP 8.42105
309 2YW2 ATP 8.42105
310 2I4O ATP 8.42105
311 2BMB PMM 8.42105
312 5DYO FLU 8.7156
313 2CDO GAL AAL GAL AAL GAL AAL 8.75
314 3X01 AMP 8.77193
315 4CC6 L5Y 8.77193
316 5INJ 6C7 8.77193
317 1BHX ASP PHE GLU GLU ILE 8.84354
318 4O4F IHP 8.87097
319 4O4F ATP 8.87097
320 5XQW 8EU 9.00474
321 5XLY C2E 9.02256
322 2QK4 ATP 9.12281
323 1M0W ANP 9.12281
324 5HWV MBN 9.23077
325 2QL9 CIT 9.27835
326 3TA2 AKG 9.32203
327 1WAP TRP 9.33333
328 5ENZ UDP 9.47368
329 4RLT FSE 9.49367
330 3WG3 A2G GAL NAG FUC 9.55056
331 5KBE IPH 9.60699
332 3A76 SPD 9.65909
333 3NOJ PYR 9.66387
334 2ZL4 ALA ALA ALA ALA 9.69388
335 3O5N BR0 9.82143
336 1U6R ADP 9.82456
337 5TSU CYS 9.82456
338 2BKK ADP 9.84848
339 3TM0 ANP 9.88593
340 3TM0 B31 9.88593
341 1VKF CIT 10.1064
342 2PNC CLU 10.1754
343 2BOS GLA GAL 10.2941
344 2BOS GLA GAL GLC 10.2941
345 5OES ADP 10.5263
346 4GLW 0XT 10.5263
347 1T36 ADP 10.5263
348 3SAO DBH 10.625
349 3G08 FEE 11.1111
350 4DFU QUE 11.2281
351 4WOE ADP 11.5789
352 1FHX 4IP 11.6279
353 5KEW 6SB 11.7021
354 4K55 H6P 12.0968
355 5VX9 FUC GAL NAG GAL BGC 12.4224
356 2VQ5 HBA 12.4378
357 5CKW ANP 12.6316
358 5F6U 5VK 12.7389
359 2AGC DAO 12.963
360 4AZW ATP 12.9825
361 4WW7 AMP 13.0268
362 5C4L SIS 13.3333
363 5C4L 4XR 13.3333
364 3TDV GDP 13.3333
365 5T96 79J 13.3333
366 3ETH ATP 13.3333
367 5C9J STE 13.879
368 2AG4 LP3 14.0244
369 6GNO XDI 14.0741
370 1LNM DTX 14.1304
371 4RT1 C2E 14.2857
372 3DJE FSA 14.7368
373 3H0L ADP 14.8936
374 2XSB GDL 15.0877
375 3ORQ ADP 15.7895
376 2P7Q GG6 16.5414
377 4MOB ADP 17.5439
378 3PN1 IVH 17.5439
379 4O1P ANP 18.2456
380 5I35 ANP 18.2456
381 3HAV ATP 18.9474
382 4XH0 ADP 21.0526
383 4IX4 ADP 21.4286
384 1J6W MET 21.7143
385 1TQP ATP 21.9858
386 4RUS NDG 22.2689
387 4RUS NAG 22.2689
388 3VHE 42Q 22.4561
389 4OAV ACP 23.5088
390 3KIF GDL 23.5849
391 5VKI THR NGA GAL NAG 23.75
392 3VV1 GAL FUC 24.375
393 1FAO 4IP 24.6032
394 4WOV 3SM 24.9123
395 5C03 AGS 24.9123
396 4CYI ATP 25.9649
397 3GNI ATP 26.3158
398 2UYN 2KT 27.1318
399 2UYP PPI 27.1318
400 1BYG STU 27.3381
401 4CLI 5P8 27.7193
402 5CIC 51R 27.7778
403 5EOB 5QQ 29.8246
404 3C1X CKK 29.8246
405 4BTK DTQ 30.1754
406 5CEO 50D 30.8772
407 5USZ SKE 31.2281
408 3LXK MI1 31.5789
409 1Y57 MPZ 31.9298
410 3UIM ANP 31.9298
411 2H8H H8H 31.9298
412 5K2M ADP 32.0755
413 1K3A ACP 32.2807
414 4IDT T28 32.2807
415 3NW7 LGV 32.6316
416 2CSN CKI 32.9825
417 3KMW ATP 33.2103
418 1VJY 460 33.3333
419 5HES 032 33.3333
420 5MJA 7O3 33.3333
421 6ES0 BW8 33.3333
422 3LXN MI1 33.6842
423 5TO8 7FM 33.6879
424 4GJ3 0XP 34.0351
425 5WNL STU 34.0351
426 5T8O 76Z 34.0351
427 4E1Z 0MX 34.386
428 3PP0 03Q 34.386
429 1JPA ANP 34.7368
430 3PLS ANP 34.7368
431 5WO4 B7V 35.0877
432 4YMJ 4EJ 35.0877
433 4EWH T77 35.2727
434 2Y6O 1N1 35.4386
435 6C7Y ADP 35.4386
436 5QIN J2V 35.4386
437 5KO1 6UY 35.689
438 5HCY 60D 35.7895
439 5VC5 96M 35.7895
440 4E93 GUI 35.7895
441 4AT3 LTI 35.7895
442 1OPK P16 35.7895
443 5JFS 6K0 36.1404
444 4P5Z Q7M 36.1404
445 4FL3 ANP 36.1404
446 4K33 ACP 36.4912
447 3G5D 1N1 36.4912
448 6A1G 9OL 36.4912
449 3RI1 3RH 36.4912
450 5NKB 8ZT 36.4912
451 2PVF ACP 36.4912
452 5U6C 7YS 36.4912
453 2OO8 RAJ 36.4912
454 2OFV 242 36.8231
455 5UR1 YY9 36.8421
456 6GWR FEW 36.8421
457 3BZ3 YAM 36.9565
458 3PVW QRX 37.193
459 1O9U ADZ 37.193
460 3BU5 ATP 37.193
461 5UKL SIX 37.193
462 2QLU ADE 37.193
463 4AG8 AXI 37.193
464 3VRY B43 37.193
465 4ASE AV9 37.193
466 5Y86 HRM 37.193
467 3EKK GS2 37.5439
468 1IR3 ANP 37.5439
469 1U59 STU 37.5439
470 3GQI ACP 37.5439
471 4TWP AXI 37.6384
472 2JLD AG1 37.8947
473 5JKG 6LF 37.8947
474 4NM5 ADP 37.8947
475 3F7Z 34O 37.8947
476 3ZRM ZRM 37.8947
477 4F4P 0SB 38.0952
478 2XVD AS6 38.2456
479 5LPZ ADP 38.2456
480 4KBA 1QM 38.2456
481 5LPB ADP 38.2456
482 5OKT 9XK 38.2456
483 3SRV S19 38.2671
484 4Y93 746 38.5965
485 2HK5 1BM 39.2593
486 5H2U 1N1 39.3258
487 4U0I 0LI 39.6491
488 6CZ3 FLJ 39.7727
489 4RFM 3P6 39.8496
490 4JH6 FCN 39.8551
491 5FBN 5WF 40.2214
492 3KRL KRL 40.7018
493 6GQM F8H 40.7018
494 5JGA 6KC 41.0526
495 4YZC STU 41.0526
496 4UXL 5P8 41.0526
497 4CSV STI 41.8182
498 4CRL C1I 42.1053
499 4Y85 499 42.1053
500 2A19 ANP 42.9577
501 4QMN DB8 43.1579
502 3H9R TAK 43.1579
503 6GIN IR2 43.1579
504 2X2M X2M 43.1579
505 4UX9 ANP 44.2105
506 4IZY 1J2 44.5614
507 3TTI KBI 44.9123
508 4WHZ 3NL 44.9123
509 5EFQ ADP 44.9123
510 3ALN ANP 44.9123
511 1ZY5 ANP 44.9123
512 3PTG 932 44.9123
513 2B9H ADP 45.2632
514 2B9I ADP 45.2632
515 2B9F ADP 45.2632
516 2B9J ADP 45.2632
517 5AWM ANP 45.2632
518 6FYV 3NG 45.614
519 2WU6 DKI 45.614
520 4NST AF3 45.9649
521 6FYL 3NG 45.9649
522 3FC2 IBI 45.9649
523 5TA6 79D 45.9649
524 6E2O S0L 45.9649
525 4NST ADP 45.9649
526 5LI1 ANP 46.3158
527 5EKO N17 46.3158
528 5MY8 RXZ 46.6667