-->
Receptor
PDB id Resolution Class Description Source Keywords
5AYV 1.65 Å EC: 1.1.1.169 CRYSTAL STRUCTURE OF ARCHAEAL KETOPANTOATE REDUCTASE COMPLEX COENZYME A AND 2-OXOPANTOATE THERMOCOCCUS KODAKARENSIS KOD1 KETOPANTOATE REDUCTASE COENZYME A FEEDBACK INHIBITION OXIDOREDUCTASE
Ref.: CRYSTAL STRUCTURE OF ARCHAEAL KETOPANTOATE REDUCTAS COMPLEXED WITH COENZYME A AND 2-OXOPANTOATE PROVIDE STRUCTURAL INSIGHTS INTO FEEDBACK REGULATION PROTEINS V. 84 374 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ACT B:405;
A:402;
A:403;
A:405;
A:404;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
submit data
59.044 C2 H3 O2 CC(=O...
MPD B:404;
B:403;
Invalid;
Invalid;
none;
none;
submit data
118.174 C6 H14 O2 C[C@@...
KPL B:402;
Valid;
none;
submit data
146.141 C6 H10 O4 CC(C)...
COA B:401;
Invalid;
none;
submit data
767.534 C21 H36 N7 O16 P3 S CC(C)...
NAP A:401;
Valid;
none;
submit data
743.405 C21 H28 N7 O17 P3 c1cc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5AYV 1.65 Å EC: 1.1.1.169 CRYSTAL STRUCTURE OF ARCHAEAL KETOPANTOATE REDUCTASE COMPLEX COENZYME A AND 2-OXOPANTOATE THERMOCOCCUS KODAKARENSIS KOD1 KETOPANTOATE REDUCTASE COENZYME A FEEDBACK INHIBITION OXIDOREDUCTASE
Ref.: CRYSTAL STRUCTURE OF ARCHAEAL KETOPANTOATE REDUCTAS COMPLEXED WITH COENZYME A AND 2-OXOPANTOATE PROVIDE STRUCTURAL INSIGHTS INTO FEEDBACK REGULATION PROTEINS V. 84 374 2016
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 5HWS - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
2 5AYV - KPL C6 H10 O4 CC(C)(CO)C....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 5HWS - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
2 5AYV - KPL C6 H10 O4 CC(C)(CO)C....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 5HWS - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
2 5AYV - KPL C6 H10 O4 CC(C)(CO)C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: KPL; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 KPL 1 1
Ligand no: 2; Ligand: NAP; Similar ligands found: 123
No: Ligand ECFP6 Tc MDL keys Tc
1 NAP 1 1
2 NA0 0.881356 0.986301
3 TAP 0.872881 0.934211
4 NDO 0.840336 0.972603
5 NAD 0.811966 0.986111
6 N01 0.733871 0.958904
7 A3D 0.712 0.972603
8 NBP 0.707692 0.935065
9 NHD 0.68254 0.958904
10 NJP 0.661417 0.972973
11 NFD 0.658915 0.934211
12 NXX 0.619048 0.959459
13 DND 0.619048 0.959459
14 AMP NAD 0.606061 0.958904
15 ZID 0.605839 0.972603
16 NAQ 0.59854 0.922078
17 ATR 0.59292 0.917808
18 NAE 0.591241 0.946667
19 NDE 0.58042 0.986301
20 A22 0.571429 0.958904
21 NAJ 0.567164 0.986111
22 A2R 0.563025 0.932432
23 NDC 0.561644 0.922078
24 NA7 0.552846 0.907895
25 ODP 0.551471 0.935065
26 A2P 0.539823 0.930556
27 8ID 0.537313 0.910256
28 NPW 0.525547 0.8875
29 NZQ 0.521739 0.910256
30 CNA 0.521739 0.959459
31 NDP 0.514493 0.922078
32 PO4 PO4 A A A A PO4 0.503937 0.930556
33 1DG 0.503401 0.922078
34 DG1 0.503401 0.922078
35 TXP 0.5 0.922078
36 NMN AMP PO4 0.492958 0.921053
37 XNP 0.492958 0.875
38 25L 0.492308 0.958904
39 25A 0.492063 0.972222
40 NMN 0.486726 0.888889
41 NGD 0.485714 0.935065
42 9JJ 0.481707 0.8875
43 2AM 0.477876 0.891892
44 ADP 0.458333 0.945205
45 PAP 0.451613 0.931507
46 A2D 0.445378 0.945205
47 AN2 0.442623 0.932432
48 7L1 0.441558 0.777778
49 ADP PO3 0.44 0.944444
50 SAP 0.44 0.896104
51 AGS 0.44 0.896104
52 M33 0.439024 0.906667
53 AR6 AR6 0.438849 0.945205
54 BA3 0.438017 0.945205
55 OAD 0.43609 0.92
56 ADP BMA 0.43609 0.92
57 DQV 0.435714 0.958904
58 HEJ 0.435484 0.945205
59 ATP 0.435484 0.945205
60 OOB 0.435115 0.958904
61 B4P 0.434426 0.945205
62 AP5 0.434426 0.945205
63 GAP 0.433071 0.92
64 0WD 0.432432 0.922078
65 2A5 0.432 0.87013
66 5FA 0.432 0.945205
67 AQP 0.432 0.945205
68 AT4 0.430894 0.907895
69 00A 0.428571 0.909091
70 DAL AMP 0.427481 0.932432
71 CA0 0.427419 0.92
72 ADP ALF 0.426357 0.871795
73 ALF ADP 0.426357 0.871795
74 9X8 0.425373 0.871795
75 ACP 0.424 0.92
76 NAJ PZO 0.423841 0.897436
77 9SN 0.423358 0.897436
78 ADP VO4 0.423077 0.932432
79 VO4 ADP 0.423077 0.932432
80 WAQ 0.422222 0.884615
81 V3L 0.421875 0.945205
82 ACQ 0.421875 0.92
83 ADQ 0.421053 0.92
84 AR6 0.420635 0.918919
85 APR 0.420635 0.918919
86 ATP A A A 0.42029 0.958333
87 CO7 0.419753 0.786517
88 3OD 0.419118 0.92
89 1ZZ 0.419118 0.841463
90 DLL 0.41791 0.958904
91 AD9 0.417323 0.92
92 NAX 0.416667 0.875
93 OVE 0.416667 0.857143
94 MYR AMP 0.416058 0.841463
95 AV2 0.415385 0.868421
96 A3P 0.414634 0.944444
97 NNR 0.414414 0.72973
98 OMR 0.413793 0.831325
99 6YZ 0.412214 0.92
100 ANP 0.410853 0.92
101 A1R 0.410448 0.860759
102 ABM 0.409836 0.893333
103 A 0.408333 0.944444
104 AMP 0.408333 0.944444
105 SON 0.408 0.933333
106 PPS 0.407692 0.829268
107 5AL 0.407692 0.932432
108 NAI 0.406897 0.909091
109 7D3 0.406504 0.857143
110 ADX 0.404762 0.829268
111 ATF 0.40458 0.907895
112 3UK 0.404412 0.945946
113 TYR AMP 0.404255 0.921053
114 AMP DBH 0.404255 0.894737
115 139 0.402685 0.875
116 50T 0.401575 0.906667
117 SRP 0.401515 0.907895
118 A A 0.40146 0.972222
119 B5V 0.40146 0.933333
120 A3R 0.4 0.860759
121 3AM 0.4 0.90411
122 B5M 0.4 0.921053
123 FA5 0.4 0.933333
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5AYV; Ligand: NAP; Similar sites found with APoc: 1025
This union binding pocket(no: 1) in the query (biounit: 5ayv.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 1I0B PEL 0.647249
2 1F06 NDP 0.970874
3 1F06 2NP 0.970874
4 5O42 9JW 1.09489
5 5O42 BGC 1.09489
6 5O42 NAD 1.09489
7 5A96 GTP 1.20482
8 1QXA GLY GLY GLY 1.2766
9 1J49 NAD 1.2945
10 4OOE FOM 1.2945
11 4OOE NDP 1.2945
12 1O0S NAI 1.61812
13 3AYI FAD 1.61812
14 3AYI HCI 1.61812
15 3CMC NAD 1.61812
16 1PJS NAD 1.61812
17 3O9Z AKG 1.61812
18 3O9Z NAD 1.61812
19 2AQJ FAD 1.61812
20 2AQJ TRP 1.61812
21 3I6I NDP 1.61812
22 6CEP NAD 1.61812
23 4TSK NDP 1.61812
24 6CEP OXM 1.61812
25 1GZ6 NAI 1.61812
26 4NBT NAD 1.66667
27 5F5N NAD 1.7301
28 4CM9 NAP 1.73611
29 5K6A NAP 1.73611
30 3JQ9 NAP 1.73611
31 5JCJ NAP 1.73611
32 3JQ8 NAP 1.73611
33 3BMN NAP 1.73611
34 5JDI NAP 1.73611
35 4CMI NAP 1.73611
36 5JDC NAP 1.73611
37 3BMO NAP 1.73611
38 3JQ7 NAP 1.73611
39 4CLR NAP 1.73611
40 3BMQ NAP 1.73611
41 3JQF NAP 1.73611
42 3JQG NAP 1.73611
43 4CM8 NAP 1.73611
44 3JQA NAP 1.73611
45 4CLO NAP 1.73611
46 4CM4 NAP 1.73611
47 3JQB NAP 1.73611
48 4CME NAP 1.73611
49 5T9E NAP 1.84502
50 2VT3 ATP 1.86047
51 2VZ0 D64 1.86567
52 2VZ0 NAP 1.86567
53 2WD7 NAP 1.86567
54 1CF2 NAP 1.94175
55 4K5S PM0 1.94175
56 4EIP FAD 1.94175
57 1BW9 NAD 1.94175
58 4B63 ORN 1.94175
59 4B63 NAP 1.94175
60 4B63 FAD 1.94175
61 1C1X NAD 1.94175
62 4EIP K2C 1.94175
63 3NYC FAD 1.94175
64 3NYC IAR 1.94175
65 1BXG NAD 1.94175
66 1SOW NAD 1.94175
67 1Q0H FOM 1.94175
68 1Q0H NDP 1.94175
69 5NA1 FAD 1.94175
70 1EZ4 NAD 1.94175
71 4EUE NAI 1.94175
72 4K5S FAD 1.94175
73 3RC1 NAP 1.94175
74 3RC1 TLO 1.94175
75 1VQW FAD 1.94175
76 2GV8 NDP 1.94175
77 2GVC FAD 1.94175
78 3GMB FAD 1.94175
79 2GV8 FAD 1.94175
80 4XFR CIT 1.94175
81 6EGU 43Y 1.94175
82 1PZG A3D 1.94175
83 5Y1G NAD 1.94175
84 5Y1G AKB 1.94175
85 1O6Z NAD 1.9802
86 2CFC NAD 2
87 2BD0 NAP 2.04918
88 6GNA FAD 2.08333
89 4ZQX ATP 2.1097
90 2RI1 GLP 2.12766
91 2CUL FAD 2.15517
92 3QWI NAP 2.22222
93 3QWI CUE 2.22222
94 2GDZ NAD 2.24719
95 3HVJ 705 2.26244
96 3KB6 NAD 2.26537
97 6C4M NAP 2.26537
98 3AXB FAD 2.26537
99 3AXB PRO 2.26537
100 5Z21 NAI 2.26537
101 5HXI FAD 2.26537
102 1HKU NAD 2.26537
103 2VVL FAD 2.26537
104 2VVM FAD 2.26537
105 4KOA NDP 2.26537
106 2GZ3 NAP 2.26537
107 5HXI 5HN 2.26537
108 3C1O NAP 2.26537
109 2XVF FAD 2.26537
110 4R5M NAP 2.26537
111 2GSD NAD 2.26537
112 4PLG NAI 2.26537
113 4PLG OXM 2.26537
114 5NUF NAD 2.26537
115 1I2B USQ 2.26537
116 1I2B NAD 2.26537
117 1I2B UPG 2.26537
118 1P0F NAP 2.26537
119 5NUE NAD 2.26537
120 5TC4 NAD 2.26537
121 4RPL FAD 2.26537
122 4RPL 3UC 2.26537
123 6C90 ADP 2.26537
124 4TQG NDP 2.26537
125 4R5M 4NO 2.26537
126 3OID NDP 2.32558
127 4YAG NAI 2.42215
128 4RF2 NAP 2.57353
129 2ZJ1 ARJ 2.589
130 2ZJ1 NAD 2.589
131 1WDK NAD 2.589
132 4XQC 13D 2.589
133 4XQC NAD 2.589
134 5W3K NDP 2.589
135 3BAZ NAP 2.589
136 5W3K 9TY 2.589
137 5Z20 NAI 2.589
138 5FJN BE2 2.589
139 5FJN FAD 2.589
140 1X7D ORN 2.589
141 1X7D NAD 2.589
142 4D04 NAP 2.589
143 4D04 FAD 2.589
144 1PL6 NAD 2.589
145 5GSN FAD 2.589
146 5GSN NAP 2.589
147 1RM0 D6P 2.589
148 1RM0 NAI 2.589
149 3H9E NAD 2.589
150 5GSN MMZ 2.589
151 3NKS FAD 2.589
152 1RM4 NDP 2.589
153 2YYY NAP 2.589
154 4USR FAD 2.589
155 2XVE FAD 2.589
156 3DAG FEG 2.589
157 2NAD NAD 2.589
158 3L4S NAD 2.589
159 1E5Q NDP 2.589
160 3L4S 3PG 2.589
161 1RPN NDP 2.589
162 1RKX NAD 2.589
163 6EL3 NAP 2.589
164 1UP7 NAD 2.589
165 2GLX NDP 2.589
166 1V35 NAI 2.589
167 4U7W NDP 2.589
168 1PL6 572 2.589
169 1WVG APR 2.589
170 2QE0 NAP 2.589
171 5Z2F NAP 2.64151
172 5JE8 NAD 2.64901
173 2P3V SRT 2.73438
174 4XUC SAM 2.75229
175 4XUC 43G 2.75229
176 5G4L NDP 2.7972
177 4NBU NAI 2.8
178 5Z2L NDP 2.85714
179 1XG5 NAP 2.86738
180 3WXB NDP 2.86738
181 1UDH URA 2.86885
182 1WMA NDP 2.89855
183 1WMA AB3 2.89855
184 4ZVV NAD 2.91262
185 4ZVV GN0 2.91262
186 4L8V NAP 2.91262
187 5J60 FAD 2.91262
188 3AB1 FAD 2.91262
189 5HSA FAS 2.91262
190 9LDT NAD 2.91262
191 5TTJ FAD 2.91262
192 5N0J FAD 2.91262
193 1PGP 6PG 2.91262
194 9LDB NAD 2.91262
195 3WLE NAD 2.91262
196 1YKF NAP 2.91262
197 2C7G FAD 2.91262
198 2C7G ODP 2.91262
199 2QZZ EMF 2.91262
200 2QZZ NAP 2.91262
201 1E1M FAD 2.91262
202 1E1M NAP 2.91262
203 1D4D FAD 2.91262
204 3OA2 NAD 2.91262
205 5MQ6 NDP 2.91262
206 4BVA T3 2.91262
207 3S5W NAP 2.91262
208 4BVA NDP 2.91262
209 1SC6 NAD 2.91262
210 5DF1 NAP 2.91262
211 5DF1 58X 2.91262
212 3S5W FAD 2.91262
213 1Y8Q ATP 2.91262
214 4YT4 FE9 2.91262
215 4W6Z 8ID 2.91262
216 2VTD LKM 2.91262
217 2FR1 NDP 2.91262
218 4B7X NAP 2.91262
219 1TB4 PEJ 2.91262
220 2PK3 A2R 2.91262
221 3IHB GLU 2.91262
222 4TXI FAD 2.92683
223 1P77 ATR 2.94118
224 4ITU NAI 2.97398
225 4ITU 1HS 2.97398
226 3AY6 BGC 2.97398
227 3AY6 NAI 2.97398
228 5OVL NAP 3
229 6GNC FAD 3.06122
230 1GEE NAD 3.06513
231 1U7T TDT 3.06513
232 1E3W NAD 3.06513
233 1U7T NAD 3.06513
234 1VM6 NAD 3.07018
235 5OJI NAP 3.07692
236 5OJI ISN 3.07692
237 1E6W NAD 3.07692
238 3B1F NAD 3.10345
239 1FK8 NAD 3.11284
240 1N5D NDP 3.125
241 1GEG NAD 3.125
242 2WSB NAD 3.14961
243 3SJ7 NDP 3.1746
244 1G0N NDP 3.18021
245 1G0N PHH 3.18021
246 1ZK4 NAP 3.18725
247 1ZK4 AC0 3.18725
248 1M0S CIT 3.19635
249 1O5I NAD 3.21285
250 5M67 NAD 3.23625
251 5M67 ADE 3.23625
252 6F3N NAD 3.23625
253 6F3N ADN 3.23625
254 5M67 3D1 3.23625
255 1GPE FAD 3.23625
256 2NVK NAP 3.23625
257 1OMO NAD 3.23625
258 4E5N NAD 3.23625
259 3E1T FAD 3.23625
260 2VYN NAD 3.23625
261 5I39 FAD 3.23625
262 4XDZ NDP 3.23625
263 5MBX FAD 3.23625
264 5MBX SP5 3.23625
265 3WGT FAD 3.23625
266 3WGT QSC 3.23625
267 3GDN FAD 3.23625
268 3GDN HBX 3.23625
269 3ZNN FAD 3.23625
270 3ZNN 4WL 3.23625
271 5E4R NAP 3.23625
272 1UXG NAD 3.23625
273 1UXG FUM 3.23625
274 6F3M NAD 3.23625
275 5J7X FAD 3.23625
276 1GAD NAD 3.23625
277 3Q9T FAY 3.23625
278 3NT6 FAD 3.23625
279 1F8G NAD 3.23625
280 1YB5 NAP 3.23625
281 4G5H NAP 3.23625
282 4G5H UD7 3.23625
283 2I3G NAP 3.23625
284 5MSO NAP 3.23625
285 5ZXD ATP 3.23625
286 2NVK FAD 3.23625
287 4R1S NAP 3.23625
288 5GWT SIN 3.23741
289 5GWT NAD 3.23741
290 2RH4 EMO 3.2491
291 1HDR NAD 3.27869
292 5O4J 9KH 3.28467
293 5O4J PJL 3.28467
294 5O4J SAH 3.28467
295 2DT5 NAD 3.31754
296 4Q9N NAI 3.3557
297 3FPF TNA 3.3557
298 3FPF MTA 3.3557
299 5NM7 GLY 3.38346
300 1H5Q NAP 3.39623
301 2XOC ADE 3.44828
302 1NFQ NAI 3.46154
303 1OAA OAA 3.4749
304 3VZS NAP 3.50195
305 3VZS CAA 3.50195
306 5OVK NDP 3.51562
307 1KOL NAD 3.51759
308 2I7C AAT 3.53357
309 3ABI NAD 3.55987
310 1T26 NAI 3.55987
311 1T26 GBD 3.55987
312 4ZGS NAD 3.55987
313 1H82 GZZ 3.55987
314 1H82 FAD 3.55987
315 4AP3 FAD 3.55987
316 4AP3 NAP 3.55987
317 3Q3C NAD 3.55987
318 1YY5 FAD 3.55987
319 4CNK FAD 3.55987
320 1Q9I TEO 3.55987
321 1Q9I FAD 3.55987
322 6BII NAP 3.55987
323 3ITJ FAD 3.55987
324 3ITJ CIT 3.55987
325 2A92 NAI 3.55987
326 2IXB NAD 3.55987
327 3ETG GTP 3.55987
328 3ETG GLU 3.55987
329 1GZ4 ATP 3.55987
330 3ETG NDP 3.55987
331 4C3Y FAD 3.55987
332 1I8T FAD 3.55987
333 2IXB A2G 3.55987
334 1CDO NAD 3.55987
335 4C3Y ANB 3.55987
336 1ZBQ NAD 3.55987
337 4DPL NAP 3.55987
338 6GAR FAD 3.55987
339 1F8F NAD 3.55987
340 1ZGS XMM 3.55987
341 1DIG NAP 3.59477
342 1DIG L37 3.59477
343 5CG1 NAD BBN 3.60656
344 2BRY FAD 3.62173
345 5T2U NAP 3.62903
346 4EA7 JB2 3.63636
347 4EA7 COA 3.63636
348 3NUG NAD 3.64372
349 5THQ NDP 3.67647
350 4WZ6 ATP 3.7931
351 4J4H NAI 3.861
352 4J4H 1J1 3.861
353 4JK3 NAD 3.861
354 4M52 FAD 3.86266
355 4M52 M52 3.86266
356 2A8X FAD 3.87931
357 1WPQ NAD 3.8835
358 3K5I AIR 3.8835
359 5A04 NDP 3.8835
360 1GQ2 NAP 3.8835
361 1X87 NAD 3.8835
362 3X0V FAD 3.8835
363 1RYD NDP 3.8835
364 1H6C NDP 3.8835
365 5XWV 8H6 3.8835
366 5XWV NDP 3.8835
367 1H6C SIN 3.8835
368 5YB7 FAD 3.8835
369 5YB7 ORN 3.8835
370 1KNR FAD 3.8835
371 5UAO FAD 3.8835
372 5GUD NDP 3.8835
373 4XYB NDP 3.8835
374 1Z45 NAD 3.8835
375 3FWN ATR 3.8835
376 4HXY NDP 3.8835
377 4XCZ T3Q 3.8835
378 2GU8 796 3.8835
379 2IVD FAD 3.8835
380 5A04 BGC 3.8835
381 6H3O FAD 3.8835
382 2Z4T C5P 3.8835
383 2C29 NAP 3.8835
384 3NB0 G6P 3.8835
385 5GUD 2IT 3.8835
386 1XHC FAD 3.8835
387 4NBW NAD 3.89105
388 3ZV6 4HB 3.91459
389 3ZV6 NAD 3.91459
390 3RJ5 NAD 3.93701
391 2Q46 NAP 3.95257
392 4B4U NAP 3.9604
393 3OZ2 FAD 4.03023
394 1XHL NDP 4.0404
395 5EES NAP 4.04858
396 1XSE NDP 4.0678
397 1WP4 NDP 4.15225
398 2CVZ NDP 4.15225
399 1ZEM NAD 4.19847
400 2O4C NAD 4.20712
401 1FEC FAD 4.20712
402 2HJR APR 4.20712
403 5TWB FAD 4.20712
404 1V8B NAD 4.20712
405 5JCM NAD 4.20712
406 5JCM ISD 4.20712
407 5JCM FAD 4.20712
408 6AIN FAD 4.20712
409 3GFB NAD 4.20712
410 2Q0L FAD 4.20712
411 2GMH FAD 4.20712
412 2DBZ NAP 4.20712
413 5UR0 NAD 4.20712
414 5BJX NAD 4.20712
415 5JY6 NAD 4.20712
416 2Q0L NAP 4.20712
417 5BJX UDP 4.20712
418 3V1Y NAD 4.20712
419 5DN9 NAD 4.20712
420 1J0X NAD 4.20712
421 3HB5 NAP 4.20712
422 1ZK7 FAD 4.20712
423 1QMG APX 4.20712
424 3M89 GSP 4.20712
425 2CVQ NDP 4.20712
426 5O98 NAP 4.20712
427 4ZRN NAD 4.20712
428 2AWN ADP 4.20712
429 4ZRN UPG 4.20712
430 4CJX NAP 4.20712
431 2JHP SAH 4.20712
432 3TWO NDP 4.20712
433 5LI9 ACP 4.20712
434 1VCO GLN 4.20712
435 1ZQ9 SAM 4.21053
436 5B4T 3HR 4.23077
437 5B4T NAD 4.23077
438 4E13 NAD 4.24028
439 5YSS NAD 4.29688
440 1W8D NAP 4.30464
441 1W73 NAP 4.30464
442 1BDB NAD 4.33213
443 1LK7 DER 4.36681
444 3ORF NAD 4.38247
445 4QED NAP 4.43548
446 1VL8 NAP 4.49438
447 1NVT NAP 4.52962
448 4OM8 NAD 4.53074
449 1LTH NAD 4.53074
450 4YKG NAD 4.53074
451 4YKG FAD 4.53074
452 1BZL GCG 4.53074
453 2HQM FAD 4.53074
454 1BZL FAD 4.53074
455 4EMI NAD 4.53074
456 1GUZ NAD 4.53074
457 4EMI FAD 4.53074
458 4EMJ FAD 4.53074
459 5BUK FAD 4.53074
460 1GV0 NAD 4.53074
461 1LDM NAD 4.53074
462 5TUF TDC 4.53074
463 1ON3 DXX 4.53074
464 2FZW NAD 4.53074
465 1KEV NDP 4.53074
466 3QJ4 FAD 4.53074
467 1DSS NAD 4.53074
468 3A06 FOM 4.53074
469 3A06 NDP 4.53074
470 5YAP 8S0 4.53074
471 4Z24 FAD 4.53074
472 4PLT NAI 4.53074
473 5TUF FAD 4.53074
474 1R6D NAD 4.53074
475 3NTD FAD 4.53074
476 4PLT OXM 4.53074
477 1R6D DAU 4.53074
478 4JJF N2I 4.53074
479 2YY7 NAD 4.53074
480 3NTA FAD 4.53074
481 3G5S FAD 4.53074
482 4JJF FE9 4.53074
483 5YAP NAI 4.53074
484 2C5A NAD 4.53074
485 2C5A GDC 4.53074
486 2DTX BMA 4.54545
487 3CH6 311 4.54545
488 3CH6 NAP 4.54545
489 3NJ4 NAD 4.5977
490 3NJ4 AFX 4.5977
491 5N6C NAD 4.66667
492 4NTD FAD 4.70588
493 4O0L NDP 4.72727
494 5Y8L NAD 4.74576
495 5Y8L HUI 4.74576
496 1NYT NAP 4.79705
497 5ZZ6 ADP 4.80769
498 5ZZ6 NAD 4.80769
499 1FL2 FAD 4.83871
500 1G2O IMH 4.85075
501 3ICT ADP 4.85437
502 3OND ADN 4.85437
503 3OND NAD 4.85437
504 1LJ8 NAD 4.85437
505 6FP4 E1T 4.85437
506 6FP4 FAD 4.85437
507 1LDN NAD 4.85437
508 3QVP FAD 4.85437
509 4X9M FAD 4.85437
510 3UOY NAP 4.85437
511 3UOY FAD 4.85437
512 1M2W NAD 4.85437
513 3ICS ADP 4.85437
514 4HA6 FAD 4.85437
515 6F97 FAD 4.85437
516 3CGB FAD 4.85437
517 1Q1R FAD 4.85437
518 2DFV NAD 4.85437
519 3ICS FAD 4.85437
520 3ICR FAD 4.85437
521 1YS4 NAP 4.85437
522 3ICT FAD 4.85437
523 5KKA 6V0 4.85437
524 3C7A NAD 4.85437
525 2RGJ FAD 4.85437
526 4O1M NAD 4.85437
527 5NII FAD 4.85437
528 1X14 NAD 4.85437
529 4MP8 MLI 4.85437
530 4MP8 NAD 4.85437
531 1US5 GLU 4.85437
532 1E3I CXF 4.85437
533 4PIV NDP 4.85437
534 2HMT NAI 4.86111
535 5EJ2 NAD 4.87013
536 3QV1 NAD 4.87805
537 1C3X 8IG 4.88722
538 3WBF NAP 4.91803
539 3WBF API 4.91803
540 1I36 NAP 4.92424
541 5X9D 80F 4.93421
542 4YUW 4JU 4.93421
543 4YUW S4M 4.93421
544 2EV9 SKM 4.94297
545 2EV9 NAP 4.94297
546 4BJZ P3A 4.95283
547 4BJZ FAD 4.95283
548 1XKQ NDP 5
549 5BSH PRO 5.05415
550 3ICC NAP 5.09804
551 1KYQ NAD 5.10949
552 1JA9 NDP 5.10949
553 6C4N NAP 5.17799
554 3GD4 FAD 5.17799
555 3LXD FAD 5.17799
556 3GD4 NAD 5.17799
557 5G3U ITW 5.17799
558 4BV6 FAD 5.17799
559 3CTY FAD 5.17799
560 3CGD FAD 5.17799
561 5BRT CH9 5.17799
562 5BVA FAD 5.17799
563 3CGD COA 5.17799
564 3CGD NAD 5.17799
565 3CIF G3H 5.17799
566 4UP3 FAD 5.17799
567 4U8P UDP 5.17799
568 4U8P FDA 5.17799
569 1VDC FAD 5.17799
570 3CIF NAD 5.17799
571 4UP3 NDP 5.17799
572 1B8U NAD 5.17799
573 5ZBC FAD 5.17799
574 1GY8 NAD 5.17799
575 3IHG FAD 5.17799
576 5G3U FDA 5.17799
577 5BRT FAD 5.17799
578 5JWC FAD 5.17799
579 2NCD ADP 5.17799
580 5YU3 PRO 5.17799
581 5YU3 NAD 5.17799
582 1B8U OAA 5.17799
583 3FPZ AHZ 5.21472
584 1FWV SGA MAG FUC 5.22388
585 3RFV NAI 5.24345
586 3RFV 15L 5.24345
587 4JNA FAD 5.29412
588 3SJU NDP 5.37634
589 2AE2 PTO 5.38462
590 2AE2 NAP 5.38462
591 2ZQO NGA 5.38462
592 1ELI PYC 5.39846
593 1E6E FAD 5.46875
594 1O8B ABF 5.47945
595 4D3F NAP 5.50162
596 2YVF FAD 5.50162
597 2YVF NAD 5.50162
598 6GAS FAD 5.50162
599 1UWK URO 5.50162
600 1UWK NAD 5.50162
601 2WET FAD 5.50162
602 5WGR FAD 5.50162
603 5KMS NAD 5.50162
604 5YEC ATP 5.50162
605 1TDF NAP 5.50162
606 1TDF FAD 5.50162
607 5NMX NAP 5.50162
608 2QRK AMP 5.50162
609 1OC2 NAD 5.50162
610 1OC2 TDX 5.50162
611 5NMX FAD 5.50162
612 2GN4 NDP 5.50162
613 5X68 FAD 5.50162
614 2GN4 UD1 5.50162
615 5KMS FAD 5.50162
616 1V6A TRE 5.50162
617 4TQK NAG 5.50162
618 2YVJ NAI 5.50459
619 2YVJ FAD 5.50459
620 3DXY SAM 5.50459
621 3H4V DVP 5.55556
622 3H4V NAP 5.55556
623 1VL1 CIT 5.60345
624 5BW4 SAM 5.61798
625 3VPH NAD 5.82524
626 3VPH OXM 5.82524
627 4J36 1HR 5.82524
628 4J36 FAD 5.82524
629 5MIT NAP 5.82524
630 5MIT FAD 5.82524
631 2YG3 FAD 5.82524
632 1RYI GOA 5.82524
633 5HV7 RBL 5.82524
634 1RYI FAD 5.82524
635 1C0I BE2 5.82524
636 1C0I FAD 5.82524
637 5K0A FAD 5.82524
638 2R4J FAD 5.82524
639 2R4J 13P 5.82524
640 1LVL NAD 5.82524
641 1LVL FAD 5.82524
642 2JB2 PHE 5.82524
643 2JB2 FAD 5.82524
644 1UDB UFG 5.82524
645 1UDB NAD 5.82524
646 1D1T NAD 5.82524
647 4DSG FAD 5.82524
648 4DSG UDP 5.82524
649 5TUK FAD 5.82524
650 6A0S HSE 5.82524
651 6A0S NDP 5.82524
652 3HQP FDP 5.82524
653 5FEU NAP 5.84192
654 1AE1 NAP 5.86081
655 3PA8 621 5.90551
656 1XCL SAH 5.95745
657 5WQP NAP 5.98291
658 5WQP NCA 5.98291
659 2D2F ADP 6
660 4KWI NAP 6.08365
661 4KWI 1TJ 6.08365
662 5ZI2 ADP 6.08696
663 5ZI2 NAD 6.08696
664 5Y77 FAD 6.14887
665 1REO FAD 6.14887
666 2Y6Q I7T 6.14887
667 5MZI FYK 6.14887
668 5MZI FAD 6.14887
669 2IID PHE 6.14887
670 2IID FAD 6.14887
671 2CDC XYP 6.14887
672 4J56 FAD 6.14887
673 1GET FAD 6.14887
674 1GET NAP 6.14887
675 2CDC XYS 6.14887
676 3ULK NDP 6.14887
677 5EZ7 FAD 6.14887
678 2E5V FAD 6.14887
679 4Z0H NAD 6.14887
680 3F8D FAD 6.14887
681 1KJ8 GAR 6.14887
682 3GGO ENO 6.14887
683 3GGO NAI 6.14887
684 2Y6Q FAD 6.14887
685 3O26 NDP 6.14887
686 4KQW NAP 6.14887
687 1EK6 NAI 6.14887
688 1ORR NAD 6.14887
689 6BWL NAD 6.14887
690 1EK6 UPG 6.14887
691 2CDC NAP 6.14887
692 4AT0 FAD 6.14887
693 3TN7 NJP 6.22568
694 6F9Q NAD 6.25
695 5OFW 9TW 6.27803
696 1RP0 AHZ 6.33803
697 1R37 NAD 6.34006
698 2G5C NAD 6.40569
699 2EWM NAD 6.4257
700 3T31 DCQ 6.47249
701 3T31 FAD 6.47249
702 2Q7V FAD 6.47249
703 5TS5 FAD 6.47249
704 1YKJ FAD 6.47249
705 1YKJ PHB 6.47249
706 3LAD FAD 6.47249
707 4XDY NAI 6.47249
708 1EBF NAD 6.47249
709 5VN0 NAI 6.47249
710 6FHO FAD 6.47249
711 5KOX RFP 6.47249
712 5KOX FAD 6.47249
713 5VN0 FAD 6.47249
714 1ZH8 NAP 6.47249
715 4IV9 FAD 6.47249
716 1LLU NAD 6.47249
717 4OSP NAP 6.47249
718 3WMX NAD 6.47249
719 5XWC 8GL 6.47249
720 5XWC NAP 6.47249
721 5XWC 2IT 6.47249
722 2JAH NDP 6.47773
723 2JAP NDP 6.47773
724 1VL0 NAI 6.50685
725 1YQD NAP 6.55738
726 3AFN NAP 6.58915
727 3A28 NAD 6.58915
728 5FFF NAP 6.61479
729 4FN4 NAD 6.69291
730 3MCT SAH 6.73401
731 1JQ3 AAT 6.75676
732 2RAB NAD 6.79612
733 3UCL NAP 6.79612
734 2RAB FAD 6.79612
735 1QO8 FAD 6.79612
736 3UCL CYH 6.79612
737 3UCL FAD 6.79612
738 4MOP 2H5 6.79612
739 2JHF NAD 6.79612
740 1PS9 FAD 6.79612
741 2B9W FAD 6.79612
742 1GR0 NAD 6.79612
743 1EQ2 NAP 6.79612
744 2X6T NAP 6.79612
745 2V6G NAP 6.79612
746 1PS9 NAP 6.79612
747 4J1Q NDP 6.79612
748 6DNT NAD 6.79612
749 3L6C MLI 6.79612
750 3H5N ATP 6.79612
751 1N7G NDP 6.79612
752 1VJT NAD 6.79612
753 1N7G GDR 6.79612
754 1LC3 NAD 6.80272
755 2F1K NAP 6.81004
756 2BGM NAJ 6.83453
757 3WV8 ATP 6.88073
758 6F7L FAD 7.01357
759 2NU8 COA 7.11974
760 4YSX FAD 7.11974
761 4MIG G3F 7.11974
762 2Q1S NAI 7.11974
763 1N1G BCP 7.11974
764 1KEW NAD 7.11974
765 1NAA 6FA 7.11974
766 1NAA ABL 7.11974
767 1KEW TYD 7.11974
768 5MLR NAP 7.11974
769 5MLR GRQ 7.11974
770 5JAQ NAI 7.11974
771 4WBD CIT 7.11974
772 6AM8 TRP 7.11974
773 4FWE FAD 7.1608
774 5N53 8NB 7.17949
775 3O03 NAP 7.2165
776 5GT9 NAP 7.22433
777 2O07 SPD 7.23684
778 2O07 MTA 7.23684
779 1MXH DHF 7.24638
780 1MXH NAP 7.24638
781 4RDH AMP 7.29167
782 4RDI ATP 7.29167
783 2AHR NAP 7.33591
784 4GUS FAD 7.34536
785 4GUT FAD 7.34536
786 4HSU FAD 7.34536
787 4GKV NAD 7.44048
788 1MUU NAD 7.44337
789 1MV8 NAD 7.44337
790 5TOW ADN 7.44337
791 5TOW NAI 7.44337
792 4NTC FAD 7.44337
793 4OPC PGT 7.44337
794 4OPC FDA 7.44337
795 1U3U BNF 7.44337
796 1U3U NAD 7.44337
797 2DKH 3HB 7.44337
798 2GCG NDP 7.44337
799 3WQQ IB3 7.44337
800 3WQQ NDP 7.44337
801 4KP7 NAP 7.44337
802 4KP7 1UQ 7.44337
803 5YLF BGC 7.44337
804 3L9W AMP 7.44337
805 3L9W GSH 7.44337
806 5EOW FAD 7.44337
807 4USQ FAD 7.44337
808 2DKH FAD 7.44337
809 5ODQ FAD 7.6087
810 4D79 ATP 7.6087
811 4J7U YTZ 7.63889
812 4J7U NAP 7.63889
813 1LUA NAP 7.66551
814 2RGH FAD 7.76699
815 4ZCC FAD 7.76699
816 4ZCC NAI 7.76699
817 5LD5 NAD 7.76699
818 5O9F 9ON 7.76699
819 5O9F NAD 7.76699
820 1HYE NAP 7.76699
821 2CDU FAD 7.76699
822 2RGO FAD 7.76699
823 2CDU ADP 7.76699
824 4D7E FAD 7.76699
825 3A4V NAD 7.76699
826 3A4V PYR 7.76699
827 4TVD BGC 7.76699
828 4MO2 FAD 7.76699
829 4MO2 FDA 7.76699
830 1COY FAD 7.76699
831 1COY AND 7.76699
832 1EJ0 SAM 7.77778
833 1EDO NAP 7.78689
834 5FI3 NAP 7.84314
835 1JNR FAD 8
836 5VKT NAP 8.01105
837 2DC1 NAD 8.05085
838 4YAC NAI 8.08081
839 5CAE SIN 8.09062
840 5CAE COA 8.09062
841 1MO9 FAD 8.09062
842 1MO9 KPC 8.09062
843 4JDR FAD 8.09062
844 1NVM NAD 8.09062
845 5AOV NAP 8.09062
846 1HDG NAD 8.09062
847 2Q1W NAD 8.09062
848 5A0U CHT 8.09062
849 5DOZ NDP 8.09062
850 4Y9D NAI 8.19672
851 5OOH NAP 8.25243
852 5OOH 9ZZ 8.25243
853 2BKA NDP 8.26446
854 6AA8 NAD 8.27815
855 2HK9 ATR 8.36364
856 2HK9 NAP 8.36364
857 3QFA FAD 8.41424
858 3FG2 FAD 8.41424
859 6C4T NA7 8.41424
860 1GTE FAD 8.41424
861 2ZXI FAD 8.41424
862 2B5W NAP 8.41424
863 2AOT SAH 8.56164
864 2NPX NAD 8.73786
865 4RSL FAD 8.73786
866 1RSG FAD 8.73786
867 2D2I NAP 8.73786
868 5EB4 FAD 8.73786
869 3B20 NAD 8.73786
870 4TM3 FAD 8.73786
871 3B1J NAD 8.73786
872 1U1I NAD 8.73786
873 3HDY FDA 8.73786
874 3HDY GDU 8.73786
875 2NPX FAD 8.73786
876 3HDY FAD 8.73786
877 5A1T NAI 8.73786
878 1SAY PYR 8.73786
879 5A1T OXM 8.73786
880 4M73 SAH 8.73786
881 4M73 M72 8.73786
882 5U5G NAP 8.81356
883 5H81 NAP 8.99743
884 2VHW NAI 9.06149
885 2Z3Y F2N 9.06149
886 6ER9 FAD 9.06149
887 5GZ6 NDP 9.06149
888 6ER9 NAP 9.06149
889 1YQZ FAD 9.06149
890 2B4R NAD 9.06149
891 2B4R AES 9.06149
892 5GZ6 7C3 9.06149
893 3SSO SAH 9.06149
894 2WPF FAD 9.38511
895 2WPF WPF 9.38511
896 1PN0 FAD 9.38511
897 1PN0 IPH 9.38511
898 5JCA NDP 9.38511
899 5JCA FAD 9.38511
900 1E7S NAP 9.38511
901 1K3T BRZ 9.38511
902 6BQ6 TER 9.38511
903 1C3V NDP 9.38776
904 2Q2V NAD 9.41177
905 3HAD NAD 9.41558
906 5L4S NAP 9.43396
907 5L4S 6KX 9.43396
908 4URS C2E 9.57447
909 1DLJ UGA 9.70874
910 3KO8 NAD 9.70874
911 2GJP MAL 9.70874
912 1DLJ NAI 9.70874
913 1IY8 NAD 9.73783
914 1JAY NAP 9.90566
915 2W9S TOP 9.93789
916 3U4C NDP 9.96441
917 5UAV NDP 10.0324
918 5UAV TFB 10.0324
919 3LZW NAP 10.0324
920 1CER NAD 10.0324
921 3LZW FAD 10.0324
922 5OJL TXP 10.0671
923 4DD8 BAT 10.0962
924 3AD8 FAD 10.101
925 3AD8 PYC 10.101
926 3AD8 NAD 10.101
927 4XYM COA 10.1293
928 2F6U CIT 10.2564
929 4XB2 NDP 10.356
930 1DJN ADP 10.356
931 4XB2 HSE 10.356
932 3H8V ATP 10.356
933 5L95 AMP 10.356
934 5Z75 NAD 10.356
935 1Y1P NMN AMP PO4 10.356
936 1BXK NAD 10.356
937 5D4V SAH 10.4478
938 4YRY NAD 10.5072
939 4YRY FAD 10.5072
940 5OCM NAP 10.6796
941 3SQP FAD 10.6796
942 2PZM NAD 10.6796
943 2PZM UDP 10.6796
944 1LSS NAD 10.7143
945 4URG C2E 10.7784
946 1G8S MET 10.8696
947 5U8U FAD 11.0032
948 4EDF UPG 11.0032
949 4MDH NAD 11.0032
950 5MDH NAD 11.0032
951 2QA1 FAD 11.0032
952 5T2Y 753 11.1111
953 1X1T NAD 11.1538
954 1NM5 NAD 11.33
955 3Q9N COA 11.3924
956 2VOH CIT 11.5385
957 3OJO NAD 11.6505
958 1NNU NAD 11.6667
959 1NNU TCT 11.6667
960 2EUG URA 11.7904
961 2D5A COA 11.8056
962 1HYH NAD 11.9741
963 5ZYN FAD 12.2977
964 1RJW ETF 12.2977
965 1OBB NAD 12.2977
966 5A3B APR 12.5413
967 4GLL NAD 12.6214
968 1J5P NAD 12.6482
969 4CQM NAP 12.7049
970 5OC1 FAD 12.945
971 5KVS NAP 12.945
972 5KVS 6XR 12.945
973 1VKO NAD 12.945
974 2OOR NAD 13.2184
975 4YNU FAD 13.2686
976 4YNU LGC 13.2686
977 4XZ3 COA 13.4783
978 1Z82 NDP 13.5922
979 5K4W THR 13.5922
980 5K4W NAI 13.5922
981 2PV7 NAD 13.7584
982 2WYV NAD 13.7931
983 6A3J SOE 14.2395
984 1O94 ADP 14.2395
985 6A3J NAI 14.2395
986 5EIN NAP 14.8148
987 2IZ1 ATR 14.8867
988 4URF NAD 14.9194
989 5U5N NAD 15.0538
990 6CI9 NAP 15.444
991 1H2B NAJ 15.534
992 1H9A NAP 15.534
993 3ZIA ADP 15.942
994 5J5Z FAD 16.8285
995 3RNM FAD 16.8285
996 2F5Z FAD 16.8285
997 1VI2 NAD 17
998 4RQU NAD 17.4757
999 1NPD NAD 17.7083
1000 1V59 FAD 17.7994
1001 1V59 NAD 17.7994
1002 3KLJ FAD 18.123
1003 1SB8 UD2 18.123
1004 1SB8 NAD 18.123
1005 3LU1 NAD 18.123
1006 2GAG FOA 18.1818
1007 2GAG FAD 18.1818
1008 2GAG NAD 18.1818
1009 2AG8 NAP 18.2509
1010 4II2 ATP 18.4049
1011 5T9F NAP 18.4466
1012 5T9F TYR 18.4466
1013 1PR9 NAP 19.2623
1014 3D3W NAP 19.2623
1015 3K7M FAD 20.0647
1016 3GF4 UPG 20.0647
1017 3GF4 FAD 20.0647
1018 5XVH NAP 20.2614
1019 1A5Z NAD 20.3883
1020 5A1S FLC 20.3883
1021 4IN9 SER TRP PHE PRO 20.4819
1022 1D7O TCL 20.5387
1023 1D7O NAD 20.5387
1024 4REP FAD 21.6828
1025 5N2I NAP 24.1379
Pocket No.: 2; Query (leader) PDB : 5AYV; Ligand: KPL; Similar sites found with APoc: 806
This union binding pocket(no: 2) in the query (biounit: 5ayv.bio1) has 36 residues
No: Leader PDB Ligand Sequence Similarity
1 5N17 8FK None
2 1F06 NDP 0.970874
3 1F06 2NP 0.970874
4 3BY9 SIN 1.15385
5 5A96 GTP 1.20482
6 1J49 NAD 1.2945
7 4OOE FOM 1.2945
8 4OOE NDP 1.2945
9 3NFD COA 1.30719
10 1PJS NAD 1.61812
11 6CEP NAD 1.61812
12 6CEP OXM 1.61812
13 4TSK NDP 1.61812
14 2AQJ FAD 1.61812
15 2AQJ TRP 1.61812
16 3AYI FAD