-->
Receptor
PDB id Resolution Class Description Source Keywords
5BSH 2.1 Å EC: 1.5.1.2 CRYSTAL STRUCTURE OF MEDICAGO TRUNCATULA (DELTA)1-PYRROLINE- CARBOXYLATE REDUCTASE (MTP5CR) IN COMPLEX WITH L-PROLINE MEDICAGO TRUNCATULA PROLINE BIOSYNTHESIS DECAMER P5C PLANT PROTEIN OXIDOREDU
Ref.: THE STRUCTURE OF MEDICAGO TRUNCATULA DELTA (1)-PYRROLINE-5-CARBOXYLATE REDUCTASE PROVIDES NEW INTO REGULATION OF PROLINE BIOSYNTHESIS IN PLANTS. FRONT PLANT SCI V. 6 869 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PRO H:301;
B:301;
J:301;
A:301;
G:301;
C:301;
E:301;
F:301;
I:301;
D:301;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
115.13 C5 H9 N O2 C1C[C...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5BSH 2.1 Å EC: 1.5.1.2 CRYSTAL STRUCTURE OF MEDICAGO TRUNCATULA (DELTA)1-PYRROLINE- CARBOXYLATE REDUCTASE (MTP5CR) IN COMPLEX WITH L-PROLINE MEDICAGO TRUNCATULA PROLINE BIOSYNTHESIS DECAMER P5C PLANT PROTEIN OXIDOREDU
Ref.: THE STRUCTURE OF MEDICAGO TRUNCATULA DELTA (1)-PYRROLINE-5-CARBOXYLATE REDUCTASE PROVIDES NEW INTO REGULATION OF PROLINE BIOSYNTHESIS IN PLANTS. FRONT PLANT SCI V. 6 869 2015
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 5BSG - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
2 5BSH - PRO C5 H9 N O2 C1C[C@H](N....
3 5BSF - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 5BSG - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
2 5BSH - PRO C5 H9 N O2 C1C[C@H](N....
3 5BSF - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
50% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2AHR - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
2 2AMF - PRO C5 H9 N O2 C1C[C@H](N....
3 5BSG - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
4 5BSH - PRO C5 H9 N O2 C1C[C@H](N....
5 5BSF - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
6 5UAV - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
7 5UAU - PRO C5 H9 N O2 C1C[C@H](N....
8 2IZZ - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
9 5UAT - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: PRO; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 PRO 1 1
2 YCP 0.769231 0.875
3 LPD 0.571429 0.722222
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5BSH; Ligand: PRO; Similar sites found with APoc: 243
This union binding pocket(no: 1) in the query (biounit: 5bsh.bio1) has 9 residues
No: Leader PDB Ligand Sequence Similarity
1 3KIF GDL None
2 3CYI ATP None
3 1DDG FAD 0.722022
4 1KMQ GNP 1.63043
5 6FA4 GNP 1.7341
6 1VI2 NAD 1.80505
7 1Q19 APC 1.80505
8 1NPD NAD 1.80505
9 4DQ2 BTX 1.80505
10 2HK9 NAP 1.81818
11 2HK9 ATR 1.81818
12 2IXE ATP 1.84502
13 4FUA PGH 1.86047
14 3IP8 B85 2.01613
15 1PN0 FAD 2.16606
16 1PN0 IPH 2.16606
17 4L2H AR6 AR6 2.16606
18 1JBW TMF 2.16606
19 5N0J FAD 2.16606
20 2IV3 UDP 2.16606
21 2Q9U FMN 2.16606
22 5HSA FAS 2.16606
23 5GWX SAR 2.16606
24 5GWX SAM 2.16606
25 4DHY GLC 2.16606
26 5VEG FMN 2.24719
27 1M5B BN1 2.28137
28 3AI8 HNQ 2.34375
29 2PZ8 APC 2.52708
30 3HQP FDP 2.52708
31 2ZIF SAM 2.52708
32 1GQ2 NAP 2.52708
33 6BC3 SIS 2.52708
34 6BC3 COA 2.52708
35 4GCS 1RG 2.52708
36 1NVV GNP 2.52708
37 3H5N ATP 2.52708
38 3GVL SLB SIA 2.52708
39 3RK0 AMP 2.53165
40 3RK1 ATP 2.53165
41 3BC1 GNP 2.5641
42 6GAQ FMN 2.5974
43 3RJ5 NAD 2.75591
44 1GAR U89 2.83019
45 4GKV NAD 2.88809
46 2IV2 2MD 2.88809
47 1YNH SUO 2.88809
48 2APC UDM 2.88809
49 3ZG6 APR 2.88809
50 4Q9N NAI 2.88809
51 4C4A SAH 2.88809
52 3UOY FAD 2.88809
53 3UOY NAP 2.88809
54 5MJI 7O6 3.11284
55 3FG2 FAD 3.2491
56 6B2M COA 3.2491
57 3FVQ ATP 3.2491
58 1LJ8 NAD 3.2491
59 6FHO FAD 3.2491
60 5TUK FAD 3.2491
61 1KNR FAD 3.2491
62 4ONQ SFG 3.2491
63 5OBU ANP 3.2491
64 1NJR XYL 3.2491
65 1M2W NAD 3.2491
66 1D6H COA 3.2491
67 2RL1 UD1 3.2491
68 2WPB ZZI 3.2491
69 1RPN NDP 3.2491
70 5IRR GSP 3.2491
71 3PC3 P1T 3.2491
72 1MOQ GLP 3.26087
73 3F6R FMN 3.37838
74 4D3S BOG 3.41297
75 1ZC3 GNP 3.42857
76 3CRZ NAP 3.50195
77 2Q2V NAD 3.52941
78 1Q1R FAD 3.61011
79 4D5G TPP 3.61011
80 4D5G FAD 3.61011
81 5MZI FAD 3.61011
82 5MZI FYK 3.61011
83 3PPM JG1 3.61011
84 1HYH NAD 3.61011
85 6FRN FMN 3.61011
86 3HVJ 705 3.61991
87 1NYT NAP 3.69004
88 5EHS 2JJ 3.73134
89 5EHS 5OY 3.73134
90 2F6U CIT 3.84615
91 1G8S MET 3.91304
92 5BRT CH9 3.97112
93 5HXI FAD 3.97112
94 5HXI 5HN 3.97112
95 2XTZ GSP 3.97112
96 5EXW 7DT 3.97112
97 3VCY UD1 3.97112
98 4MOP 2H5 3.97112
99 6ASY ATP 3.97112
100 5OJ7 AR6 3.97112
101 1P4A PCP 3.97112
102 2XVF FAD 3.97112
103 5DN9 NAD 3.97112
104 5IVX ARG GLY PRO GLY ARG ALA PHE VAL THR ILE 4
105 2FFQ GSP 4.09357
106 1NF3 GNP 4.10256
107 4HEQ FMN 4.10959
108 1WPY BTN 4.25532
109 5BUK FAD 4.33213
110 2OHH FMN 4.33213
111 1SC6 NAD 4.33213
112 5K0A FAD 4.33213
113 4O6M C5P 4.33213
114 6F7L FAD 4.33213
115 1ZK7 FAD 4.33213
116 5MQ6 NDP 4.33213
117 4WXJ GLU 4.46097
118 6BSX E7S 4.49438
119 3GFS FMN 4.5977
120 5AHN IMP 4.69314
121 5H68 AGS 4.69314
122 5UY8 AMZ 4.69314
123 2Z3Y F2N 4.69314
124 2CH5 NAG 4.69314
125 2CXS F6P 4.69314
126 2CH5 NDG 4.69314
127 2V2V V12 4.79705
128 1NNU TCT 4.80349
129 1NNU NAD 4.80349
130 2XNJ NAP 4.88722
131 1T5B FMN 4.97512
132 4KVG GTP 5
133 3LXD FAD 5.05415
134 6GNA FAD 5.05415
135 5EE5 GTP 5.16432
136 2GJ8 ALF GDP 5.23256
137 1U8Z GDP 5.35714
138 1YZN GNP 5.40541
139 3NJ4 NAD 5.41516
140 1JNR FAD 5.41516
141 3TWO NDP 5.41516
142 1GTE FAD 5.41516
143 1E96 GTP 5.41872
144 1YQD NAP 5.46448
145 1XNG ATP 5.59701
146 4LHW GNP 5.74713
147 2Q8Z NUP 5.77617
148 3EFS BTN 6.00858
149 3WB0 FEG 6.0241
150 5T2Y 753 6.06061
151 5LJI FMN 6.08108
152 1HXD BTN 6.13718
153 2VHW NAI 6.13718
154 4E3Q PMP 6.13718
155 6F9Q NAD 6.25
156 3AD8 NAD 6.4982
157 4YSX FAD 6.4982
158 4AMV F6R 6.4982
159 4ZVV GN0 6.4982
160 4ZVV NAD 6.4982
161 1GZ4 ATP 6.4982
162 4IP7 FBP 6.4982
163 3GDN FAD 6.4982
164 3GDN HBX 6.4982
165 2QQ0 ANP 6.52174
166 5KVA SAM 6.83453
167 2A3Z ATP 6.85921
168 4PKG ATP 6.85921
169 3U9Z ADP 6.85921
170 2FXU ATP 6.85921
171 5YPU ATP 6.85921
172 3MN6 ATP 6.85921
173 2QTV GNP 6.85921
174 4Z94 ATP 6.85921
175 3ULK NDP 6.85921
176 2Y5S 78H 6.85921
177 1M2O GNP 6.85921
178 3MN9 ATP 6.85921
179 5VM0 9EG 7.03125
180 3MN7 ATP 7.14286
181 4PTZ FMN 7.32984
182 1HTW ADP 7.59494
183 4LTN FMN 7.61421
184 4LTN NAI 7.61421
185 3A6T 8OG 7.75194
186 3WYF GTP 7.76256
187 4X9M FAD 7.94224
188 3WCZ NAP 7.94224
189 2IVF MGD 7.94224
190 5A5W GUO 7.94224
191 2HJR APR 7.94224
192 3SHR CMP 8.30325
193 2Q97 ATP 8.52713
194 2XHK AKG 8.55856
195 1KYV RBF 8.80503
196 1AKV FMN 8.84354
197 3RAB GNP 8.87574
198 2YVJ FAD 9.17431
199 2HV8 GTP 9.375
200 1K0E TRP 9.38628
201 5N0L ILE 9.43396
202 4PL8 ATP 9.58904
203 4R74 F6P 9.74729
204 2C7G ODP 9.74729
205 2C7G FAD 9.74729
206 1LDN NAD 9.74729
207 4RHE FMN 10.0478
208 2GAG FOA 10.101
209 2GAG NAD 10.101
210 3Q9T FAY 10.1083
211 1BZL FAD 10.1083
212 2J59 GTP 10.119
213 1L2T ATP 10.2128
214 1Q79 3AT 10.4693
215 4BAS GNP 10.5528
216 1KQP ADJ 10.7011
217 4HDO GNP 10.7784
218 3X1Z GNP 10.7784
219 4HDQ GNP 10.7784
220 1JGT APC 10.8303
221 1JGT CMA 10.8303
222 3G6K POP 11.1913
223 3G6K FAD 11.1913
224 1KEW NAD 11.1913
225 1KEW TYD 11.1913
226 1BXK NAD 11.1913
227 1F8F NAD 11.1913
228 1MJH ATP 12.3457
229 3PCR GTP 12.3457
230 3B4Y F42 12.6354
231 3U4L ATP 13.5714
232 2PAV ATP 13.6691
233 2F59 INI 14.0127
234 4XTX 590 14.8148
235 5TOW NAI 15.8845
236 5TOW ADN 15.8845
237 5AHW CMP 16.3265
238 3KLJ FAD 17.6895
239 5UPK GNP 18.75
240 2FF3 ATP 21.3333
241 2D1K ATP 21.875
242 5UWW GNP 33.3333
243 4B1W ATP 34.375
Pocket No.: 2; Query (leader) PDB : 5BSH; Ligand: PRO; Similar sites found with APoc: 487
This union binding pocket(no: 2) in the query (biounit: 5bsh.bio1) has 32 residues
No: Leader PDB Ligand Sequence Similarity
1 1FWV SGA MAG FUC None
2 3AJ4 SEP None
3 1P77 ATR 1.10294
4 1RM0 D6P 1.44404
5 1RM0 NAI 1.44404
6 1D1T NAD 1.44404
7 2CVZ NDP 1.80505
8 1CER NAD 1.80505
9 5M67 ADE 1.80505
10 5M67 NAD 1.80505
11 3OA2 NAD 1.80505
12 5M67 3D1 1.80505
13 4YT4 FE9 1.80505
14 3CMC NAD 1.80505
15 3ETG GLU 1.80505
16 3ETG NDP 1.80505
17 5NUF NAD 1.80505
18 5NUE NAD 1.80505
19 1F06 NDP 1.80505
20 1F06 2NP 1.80505
21 1NME 159 2.05479
22 1PZG A3D 2.1148
23 1GUZ NAD 2.16606
24 1GV0 NAD 2.16606
25 1BXG NAD 2.16606
26 1O6Z NAD 2.16606
27 1BW9 NAD 2.16606
28 6CEP NAD 2.16606
29 1C1X NAD 2.16606
30 5LD5 NAD 2.16606
31 6CEP OXM 2.16606
32 1X7D ORN 2.16606
33 1ZH8 NAP 2.16606
34 5H81 NAP 2.16606
35 4PLT OXM 2.16606
36 3L4S NAD 2.16606
37 2DFV NAD 2.16606
38 3V1Y NAD 2.16606
39 5UR0 NAD 2.16606
40 4PLT NAI 2.16606
41 3L4S 3PG 2.16606
42 3UCL NAP 2.16606
43 1GAD NAD 2.16606
44 4PLG NAI 2.16606
45 4PLG OXM 2.16606
46 1HDG NAD 2.16606
47 1X7D NAD 2.16606
48 1J0X NAD 2.16606
49 4KP7 1UQ 2.16606
50 1PJS NAD 2.16606
51 3UCL CYH 2.16606
52 3UCL FAD 2.16606
53 4KP7 NAP 2.16606
54 1LLU NAD 2.16606
55 1H82 GZZ 2.16606
56 1H82 FAD 2.16606
57 2GZ3 NAP 2.16606
58 4XQC 13D 2.16606
59 3WQQ NDP 2.16606
60 3WQQ IB3 2.16606
61 2B4R NAD 2.16606
62 4XQC NAD 2.16606
63 2B4R AES 2.16606
64 3H9E NAD 2.16606
65 1E3I CXF 2.16606
66 4Z0H NAD 2.16606
67 1DSS NAD 2.16606
68 1RYD NDP 2.16606
69 1K3T BRZ 2.16606
70 1YP4 ADP 2.16606
71 4XYB NDP 2.16606
72 5G4L NDP 2.16606
73 1ONI BEZ 2.17391
74 1OAA OAA 2.3166
75 1C3V NDP 2.44898
76 3ABI NAD 2.46575
77 1LTH NAD 2.52708
78 2CDU ADP 2.52708
79 3VCA PRO 2.52708
80 1EBF NAD 2.52708
81 4B4U NAP 2.52708
82 1YKF NAP 2.52708
83 1Q0H NDP 2.52708
84 1Q0H FOM 2.52708
85 1V59 NAD 2.52708
86 1VJT NAD 2.52708
87 3LST SAH 2.52708
88 4FWE FAD 2.52708
89 1YKJ PHB 2.52708
90 1YKJ FAD 2.52708
91 1VL0 NAI 2.52708
92 1RSG FAD 2.52708
93 3FWN ATR 2.52708
94 1YY5 FAD 2.52708
95 5A04 BGC 2.52708
96 4D04 NAP 2.52708
97 4D04 FAD 2.52708
98 1V59 FAD 2.52708
99 5A04 NDP 2.52708
100 1OBB NAD 2.52708
101 2DC1 NAD 2.54237
102 5WQP NAP 2.5641
103 4YKG NAD 2.68714
104 4EA7 JB2 2.72727
105 4EA7 COA 2.72727
106 2DT5 NAD 2.8436
107 1OMO NAD 2.88809
108 5AOG IAC 2.88809
109 6C4N NAP 2.88809
110 3Q3C NAD 2.88809
111 3OJO NAD 2.88809
112 1F8G NAD 2.88809
113 1GET NAP 2.88809
114 1YS4 NAP 2.88809
115 1E1M FAD 2.88809
116 1E1M NAP 2.88809
117 1H6C SIN 2.88809
118 1NVT NAP 2.88809
119 1B8U NAD 2.88809
120 5VN0 NAI 2.88809
121 6GVZ CHO 2.88809
122 1KJ8 GAR 2.88809
123 1X87 NAD 2.88809
124 1GET FAD 2.88809
125 1H6C NDP 2.88809
126 1UWK NAD 2.88809
127 1UWK URO 2.88809
128 1LVW TYD 2.88809
129 5OOH 9ZZ 2.91262
130 5OOH NAP 2.91262
131 5FFF NAP 3.11284
132 3OJF IMJ 3.11284
133 3VZS CAA 3.11284
134 3ORF NAD 3.18725
135 1YJQ NAP 3.2491
136 1WDK NAD 3.2491
137 5X20 NAD 3.2491
138 4BVA NDP 3.2491
139 1PL6 NAD 3.2491
140 2O4C NAD 3.2491
141 3CIF NAD 3.2491
142 1O0S NAI 3.2491
143 3SQP FAD 3.2491
144 4BVA T3 3.2491
145 3CIF G3H 3.2491
146 4WCX MET 3.2491
147 1PL6 572 3.2491
148 1SAY PYR 3.2491
149 4J7U YTZ 3.2491
150 1FEC FAD 3.2491
151 6A0S NDP 3.2491
152 6A0S HSE 3.2491
153 4J7U NAP 3.2491
154 2NAD NAD 3.2491
155 1TB4 PEJ 3.2491
156 5J60 FAD 3.2491
157 3C1O NAP 3.2491
158 3C7A NAD 3.2491
159 2BKA NDP 3.30579
160 2HMT NAI 3.47222
161 4JK3 NAD 3.4749
162 4J4H NAI 3.4749
163 4J4H 1J1 3.4749
164 5OCM NAP 3.61011
165 3GGO NAI 3.61011
166 3GGO ENO 3.61011
167 5N6C NAD 3.61011
168 1J49 NAD 3.61011
169 2ZJ1 ARJ 3.61011
170 2ZJ1 NAD 3.61011
171 1V8B NAD 3.61011
172 4L8V NAP 3.61011
173 5NMX NAP 3.61011
174 5Y77 FAD 3.61011
175 1P0F NAP 3.61011
176 6ER9 FAD 3.61011
177 6ER9 NAP 3.61011
178 2IID PHE 3.61011
179 2IID FAD 3.61011
180 2A8X FAD 3.61011
181 4M52 FAD 3.61011
182 4D79 ATP 3.62319
183 3B1F NAD 3.97112
184 4E13 NAD 3.97112
185 3VPH OXM 3.97112
186 3VPH NAD 3.97112
187 1EZ4 NAD 3.97112
188 1SOW NAD 3.97112
189 1CDO NAD 3.97112
190 5AOA PPI 3.97112
191 3WBF NAP 3.97112
192 1X14 NAD 3.97112
193 5ZI2 NAD 3.97112
194 1U3U BNF 3.97112
195 1U3U NAD 3.97112
196 5ZI2 ADP 3.97112
197 3T31 DCQ 3.97112
198 3T31 FAD 3.97112
199 3WBF API 3.97112
200 1H2B NAJ 3.97112
201 2YVF NAD 3.97112
202 2YVF FAD 3.97112
203 3RC1 NAP 3.97112
204 5GUD NDP 3.97112
205 3RC1 TLO 3.97112
206 5GUD 2IT 3.97112
207 5XWV 8H6 3.97112
208 2Q7V FAD 3.97112
209 4BJZ FAD 3.97112
210 5XWV NDP 3.97112
211 4BJZ P3A 3.97112
212 4OHU NAD 3.97112
213 4OHU 2TK 3.97112
214 3WMX NAD 3.97112
215 5EOW FAD 3.97112
216 3HB5 NAP 3.97112
217 4XB2 NDP 4.1791
218 4XB2 HSE 4.1791
219 2FZW NAD 4.28954
220 6F3N ADN 4.33213
221 5U5G NAP 4.33213
222 6F3N NAD 4.33213
223 1UXG FUM 4.33213
224 1UXG NAD 4.33213
225 3OND ADN 4.33213
226 3OND NAD 4.33213
227 5J5Z FAD 4.33213
228 6F3M NAD 4.33213
229 3O9Z AKG 4.33213
230 3O9Z NAD 4.33213
231 4JBI NDP 4.33213
232 5JY6 NAD 4.33213
233 4XZ3 COA 4.34783
234 3GFB NAD 4.69314
235 2GCG NDP 4.69314
236 3BAZ NAP 4.69314
237 2D2I NAP 4.69314
238 3B20 NAD 4.69314
239 1LVL NAD 4.69314
240 1KEV NDP 4.69314
241 4MP8 MLI 4.69314
242 4MP8 NAD 4.69314
243 3B1J NAD 4.69314
244 4OOE NDP 4.69314
245 4OOE FOM 4.69314
246 1OFL NGK GCD 4.69314
247 2F5X ASP 4.69314
248 5L53 NAP 4.69314
249 5L4S 6KX 4.69314
250 5L4S NAP 4.69314
251 1KOL NAD 4.69314
252 5Z2F NAP 4.90566
253 5AYV NAP 5.05415
254 5JE8 NAD 5.05415
255 5AYV KPL 5.05415
256 3L9W AMP 5.05415
257 4EDF UPG 5.05415
258 3H8V ATP 5.05415
259 2VYN NAD 5.05415
260 5KKA 6V0 5.05415
261 2RAB NAD 5.05415
262 1QMG APX 5.05415
263 2JHF NAD 5.05415
264 4DPL NAP 5.05415
265 5L95 AMP 5.05415
266 5VKT NAP 5.05415
267 2RAB FAD 5.05415
268 2E5V FAD 5.05415
269 5FI3 NAP 5.05415
270 3FPZ AHZ 5.05415
271 5TC4 NAD 5.37975
272 5E4R NAP 5.41516
273 4XDZ NDP 5.41516
274 3NJ4 AFX 5.41516
275 2A92 NAI 5.41516
276 4ZGS NAD 5.41516
277 4RDH AMP 5.41516
278 2IXB NAD 5.41516
279 1N1G BCP 5.41516
280 4RDI ATP 5.41516
281 6A3J SOE 5.41516
282 6A3J NAI 5.41516
283 2QRK AMP 5.41516
284 4EIP FAD 5.41516
285 2IXB A2G 5.41516
286 1T26 GBD 5.41516
287 1T26 NAI 5.41516
288 4EIP K2C 5.41516
289 4UP3 NDP 5.41516
290 3R75 PYR 5.41516
291 1GZ6 NAI 5.41516
292 5O9F NAD 5.41516
293 5O9F 9ON 5.41516
294 1DRV A3D 5.49451
295 5EES NAP 5.66802
296 1NVM NAD 5.76923
297 5OJL TXP 5.77617
298 6C4T NA7 5.77617
299 1WPQ NAD 5.77617
300 6C4M NAP 5.77617
301 1DIG NAP 5.77617
302 3WLE NAD 5.77617
303 5CG1 NAD BBN 5.77617
304 1DIG L37 5.77617
305 1QG6 NAD 6.13027
306 1QG6 TCL 6.13027
307 1HYE NAP 6.13718
308 9LDT NAD 6.13718
309 9LDB NAD 6.13718
310 1RM4 NDP 6.13718
311 1V6A TRE 6.13718
312 4W6Z 8ID 6.13718
313 2IZ1 ATR 6.13718
314 4EMI NAD 6.13718
315 3LZW FAD 6.13718
316 3LZW NAP 6.13718
317 6H45 QEI 6.13718
318 1NU4 MLA 6.18557
319 1U1I NAD 6.37755
320 5ODQ FAD 6.42857
321 1MUU NAD 6.4982
322 1MV8 NAD 6.4982
323 6AA8 NAD 6.4982
324 1CF2 NAP 6.4982
325 1E5Q NDP 6.4982
326 1UP7 NAD 6.4982
327 2B5W NAP 6.4982
328 3CGD FAD 6.4982
329 3GDN MXN 6.4982
330 5JCM ISD 6.4982
331 5JCM FAD 6.4982
332 5JCM NAD 6.4982
333 3CGD NAD 6.4982
334 3CGD COA 6.4982
335 3AYI HCI 6.4982
336 3AYI FAD 6.4982
337 1LC3 NAD 6.4982
338 1HFE CYS 6.50407
339 1MO9 FAD 6.85921
340 1MO9 KPC 6.85921
341 1Y1P NMN AMP PO4 6.85921
342 5XWC 8GL 6.85921
343 5XWC NAP 6.85921
344 5XWC 2IT 6.85921
345 3B8I OXL 6.85921
346 6FP4 E1T 6.85921
347 6FP4 FAD 6.85921
348 2YG3 FAD 6.85921
349 3CTY FAD 6.85921
350 3DUV KDO 6.87023
351 1WMA NDP 6.88406
352 1WMA AB3 6.88406
353 5T9E NAP 7.01107
354 1JAY NAP 7.07547
355 1LSS NAD 7.14286
356 1I36 NAP 7.19697
357 5E5U 1PS 7.19697
358 2G5C NAD 7.22022
359 5Z20 NAI 7.22022
360 4XYM COA 7.22022
361 5X9D 80F 7.22022
362 1WP4 NDP 7.22022
363 1DJN ADP 7.22022
364 5YAP 8S0 7.22022
365 3LAD FAD 7.22022
366 5YAP NAI 7.22022
367 1KYQ NAD 7.29927
368 1A5Z NAD 7.58123
369 2WPF FAD 7.58123
370 2WPF WPF 7.58123
371 3NGL NAP 7.6087
372 4G9N NGA 7.69231
373 5T9F NAP 7.74908
374 5T9F TYR 7.74908
375 3WV8 ATP 7.79817
376 5W3K NDP 7.94118
377 5W3K 9TY 7.94118
378 4D3F NAP 7.94224
379 3ICS ADP 7.94224
380 3ICT ADP 7.94224
381 5CAE COA 7.94224
382 2NU8 COA 7.94224
383 5CAE SIN 7.94224
384 1ZQ9 SAM 7.94224
385 4RQU NAD 7.94224
386 4II2 ATP 7.94224
387 5O98 NAP 7.94224
388 4TM3 FAD 7.94224
389 2EV9 SKM 7.98479
390 3HAD NAD 8.30325
391 1GR0 NAD 8.30325
392 5YEC ATP 8.30325
393 4AQ0 DMJ 8.30325
394 2WET FAD 8.30325
395 5GZ6 NDP 8.66426
396 4KQW NAP 8.66426
397 5GZ6 7C3 8.66426
398 3QFA FAD 8.66426
399 5D63 FUC GAL GLA 8.66426
400 2VT3 ATP 8.83721
401 3S5W NAP 9.02527
402 2YVJ NAI 9.17431
403 2OOR NAD 9.1954
404 5EIN NAP 9.25926
405 1PGP 6PG 9.38628
406 4E5N NAD 9.38628
407 1J5P NAD 9.38628
408 5ZZ6 ADP 9.61539
409 5ZZ6 NAD 9.61539
410 2F1K NAP 9.74729
411 4TSK NDP 9.74729
412 5KVS NAP 9.74729
413 3A06 NDP 9.74729
414 5KVS 6XR 9.74729
415 4R5M NAP 9.74729
416 2NPX NAD 9.74729
417 3A06 FOM 9.74729
418 1LES GLC FRU 9.94475
419 2Q0L NAP 10.1083
420 1O94 ADP 10.1083
421 1BZL GCG 10.1083
422 2Y6Q I7T 10.1083
423 2Y6Q FAD 10.1083
424 2Q0L FAD 10.1083
425 4OKD GLC GLC GLC 10.1083
426 5NM7 GLY 10.1504
427 5Y8L HUI 10.1695
428 5Y8L NAD 10.1695
429 1ZEM NAD 10.3053
430 2PV7 NAD 10.4693
431 2NVK NAP 10.4693
432 2NVK FAD 10.4693
433 2QZZ NAP 10.4693
434 2QZZ EMF 10.4693
435 2GMH FAD 10.4693
436 5N2I NAP 10.7759
437 4JJF FE9 10.8303
438 4JJF N2I 10.8303
439 3GD4 NAD 10.8303
440 4J36 FAD 11.1913
441 4J36 1HR 11.1913
442 1FK8 NAD 11.284
443 1LDM NAD 11.9134
444 5MIT FAD 12.2744
445 5MIT NAP 12.2744
446 4YCA NDP 12.6354
447 1VM6 NAD 12.7193
448 5XVH NAP 12.9964
449 2CDC XYP 12.9964
450 2CDC XYS 12.9964
451 5U8U FAD 12.9964
452 3DAG FEG 12.9964
453 2CDC NAP 12.9964
454 4CQM NAP 13.1148
455 6BII NAP 13.3574
456 4XDY NAI 13.3574
457 3KB6 NAD 13.3574
458 3QV1 NAD 13.4146
459 2Q46 NAP 13.4387
460 5U5N NAD 13.6201
461 5YU3 PRO 13.7184
462 5YU3 NAD 13.7184
463 4JDR FAD 13.7184
464 4CJX NAP 14.0794
465 3I6I NDP 14.0794
466 2GSD NAD 14.0794
467 2DBZ NAP 14.3713
468 1Z82 NDP 14.4404
469 4GUT FAD 14.5161
470 4GUS FAD 14.5161
471 4HSU FAD 14.5161
472 2GLX NDP 14.8014
473 2YYY NAP 15.1625
474 5A1T OXM 15.1625
475 2I3G NAP 15.1625
476 5A1T NAI 15.1625
477 1HKU NAD 15.5235
478 5Z21 NAI 15.8845
479 4KOA NDP 17.3285
480 5AOV NAP 17.6895
481 1DLJ NAI 20.2166
482 1DLJ UGA 20.2166
483 4J56 FAD 20.2166
484 4OM8 NAD 21.6607
485 1VKO NAD 22.7437
486 1LUA NAP 23.8267
487 2AG8 NAP 49.4297
Pocket No.: 3; Query (leader) PDB : 5BSH; Ligand: PRO; Similar sites found with APoc: 31
This union binding pocket(no: 3) in the query (biounit: 5bsh.bio1) has 32 residues
No: Leader PDB Ligand Sequence Similarity
1 4AP9 1PS 1.49254
2 3K7M FAD 2.16606
3 2I5F 5IP 2.75229
4 4K91 SIN 2.88809
5 3VZS NAP 3.11284
6 3OJF NDP 3.11284
7 1ZGS XMM 3.61011
8 4UMJ BFQ 3.61011
9 1H5R THM 3.97112
10 5MBX SP5 3.97112
11 5MBX FAD 3.97112
12 1XG5 NAP 3.97112
13 5CWA 0GA 3.97112
14 5EXK MET 4.69314
15 3R7F CP 5.05415
16 4XFR CIT 5.05415
17 2UVO NAG 5.26316
18 3OBT SLB 5.41516
19 4D42 W0I 5.77617
20 4D42 NAP 5.77617
21 5KK4 44E 6.25
22 2VOH CIT 6.36943
23 5TS5 FAD 7.22022
24 2AQJ TRP 7.22022
25 2AQJ FAD 7.22022
26 1KQR MNA 9.49721
27 5OVL NAP 10.1083
28 5WUW NAP 10.1083
29 5OVK NDP 10.9375
30 3RNM FAD 13.7931
31 2F5Z FAD 29.6875
Pocket No.: 4; Query (leader) PDB : 5BSH; Ligand: PRO; Similar sites found with APoc: 36
This union binding pocket(no: 4) in the query (biounit: 5bsh.bio1) has 32 residues
No: Leader PDB Ligand Sequence Similarity
1 1N7G GDR 1.80505
2 1N7G NDP 1.80505
3 5KMS NAD 2.16606
4 2ATJ BHO 2.16606
5 3O26 NDP 2.16606
6 4Y9D NAI 2.52708
7 2PK3 A2R 2.52708
8 3E1T FAD 2.52708
9 5WQP NCA 2.5641
10 1UDB UFG 3.2491
11 1UDB NAD 3.2491
12 1HSR BHO 3.61011
13 1ML4 PAL 3.97112
14 5O42 BGC 4.0146
15 5O42 9JW 4.0146
16 5O42 NAD 4.0146
17 4K5S PM0 4.69314
18 4K5S FAD 4.69314
19 1NXJ GLV 4.91803
20 5TUF FAD 5.05415
21 5TUF TDC 5.05415
22 2YY7 NAD 5.05415
23 1EK6 NAI 5.05415
24 1Y8Q ATP 5.05415
25 1EK6 UPG 5.05415
26 2FR1 NDP 5.77617
27 5OJY CIT 6.29921
28 1H74 ILE 6.4982
29 1WRA PC 6.85921
30 3OIG NAD 7.14286
31 4IEE AGS 7.22022
32 5JWC FAD 7.58123
33 2GV8 NDP 7.58123
34 1XHC FAD 9.74729
35 3GD4 FAD 10.8303
36 5TWB FAD 11.5523
Pocket No.: 5; Query (leader) PDB : 5BSH; Ligand: PRO; Similar sites found with APoc: 13
This union binding pocket(no: 5) in the query (biounit: 5bsh.bio1) has 33 residues
No: Leader PDB Ligand Sequence Similarity
1 5X68 FAD 2.16606
2 5FFF 5XC 3.11284
3 1T36 ORN 3.97112
4 2AE2 PTO 4.23077
5 2AE2 NAP 4.23077
6 5KOX RFP 4.33213
7 5KOX FAD 4.33213
8 4WOV 3SM 5.05415
9 5DF1 58X 5.05415
10 5DF1 NAP 5.05415
11 3BRE C2E 6.13718
12 6AM8 TRP 7.58123
13 3B6R CRN 15.8845
Pocket No.: 6; Query (leader) PDB : 5BSH; Ligand: PRO; Similar sites found with APoc: 55
This union binding pocket(no: 6) in the query (biounit: 5bsh.bio1) has 32 residues
No: Leader PDB Ligand Sequence Similarity
1 2IBN I1N 1.6
2 3ETG GTP 1.80505
3 1OC2 NAD 1.80505
4 1OC2 TDX 1.80505
5 2BQP GLC 2.13675
6 1TDF NAP 2.16606
7 1TDF FAD 2.16606
8 4JNA FAD 2.16606
9 1W73 NAP 2.16606
10 1W6U NAP 2.16606
11 1W8D NAP 2.16606
12 4OPC PGT 2.16606
13 4YKG FAD 2.68714
14 3JQQ A2P 2.88809
15 5BJX NAD 2.88809
16 5BJX UDP 2.88809
17 3GEG NAD 3.23887
18 1PS9 FAD 3.2491
19 2QA1 FAD 3.4
20 4J1Q NDP 3.61011
21 5BVA FAD 3.61011
22 4M52 M52 3.61011
23 3ITJ FAD 3.61011
24 5LI1 ANP 3.97112
25 4B63 FAD 3.97112
26 4B63 NAP 3.97112
27 4B63 ORN 3.97112
28 5BRT FAD 3.97112
29 6AIN FAD 4.33213
30 1YQZ FAD 4.33213
31 1I7M PUT 4.47761
32 2Q1S NAI 4.69314
33 4MDH NAD 4.69314
34 1REO FAD 4.69314
35 3SJU NDP 5.41516
36 5LQ8 GB 5.77617
37 3A4V NAD 5.77617
38 3A4V PYR 5.77617
39 4HXY NDP 5.77617
40 5YB7 FAD 6.13718
41 5YB7 ORN 6.13718
42 4ZXA H8N 6.13718
43 1L7E NAI 6.13718
44 4NTC FAD 6.4982
45 3OZ2 FAD 6.4982
46 3WCZ CIT 7.94224
47 4KWI 1TJ 7.98479
48 4KWI NAP 7.98479
49 3AB1 FAD 8.30325
50 3LRE ADP 8.66426
51 5TTJ FAD 8.66426
52 4BV6 FAD 10.8303
53 2HQM FAD 12.6354
54 1B4U DHB 12.9496
55 5KHD C2E 31.8681
Pocket No.: 7; Query (leader) PDB : 5BSH; Ligand: PRO; Similar sites found with APoc: 50
This union binding pocket(no: 7) in the query (biounit: 5bsh.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 3U2U UDP 1.14068
2 1X1R GDP 1.68539
3 1KAO GDP 1.79641
4 5ZQY AR6 1.80505
5 2YYJ 4HP 1.80505
6 4KVA GTP 2.16606
7 2Q89 6CS 2.33463
8 3D3W NAP 2.45902
9 5WM2 AMP 2.52708
10 3KC1 2T6 2.52708
11 6DEF GCP 2.52708
12 4KCT FDP 2.52708
13 1ZFJ IMP 2.88809
14 4YRY FAD 2.88809
15 2G50 ALA 2.88809
16 2IVD FAD 3.2491
17 2WC1 FMN 3.2967
18 4GLL NAD 3.61011
19 3TLJ SAH 3.61011
20 5W71 9YM 3.61011
21 5W71 PLP 3.61011
22 4ZFL 4NK 3.61011
23 1ZGD NAP 3.97112
24 5I60 67W 3.97112
25 3RUV ANP 4.33213
26 6BSX GDP 4.49438
27 2WOE AR6 4.69314
28 5DK4 ATP 4.69314
29 5DK4 5BX 4.69314
30 5UQW GDP 4.7619
31 4K2M O1G 5.05415
32 6F05 GTS 5.5814
33 3QBT GNP 5.74713
34 3A28 NAD 5.81395
35 5K8C NAD 6.13718
36 3LL9 ADP 6.3197
37 4D9C PMP 7.22022
38 5GM9 CBI 7.51174
39 2IVF MD1 7.94224
40 1YAG ATP 8
41 5DT6 GLU 8.61423
42 3HGM ATP 8.84354
43 3TYZ PAB 9.74729
44 3KAP FMN 11.5646
45 3T12 GDP ALF 11.7647
46 1IK4 PGH 11.8421
47 3NKV GNP 12.5714
48 1Z0K GTP 14.4928
49 4Z24 FAD 17.6895
50 1GWN GTP 18.5366
Pocket No.: 8; Query (leader) PDB : 5BSH; Ligand: PRO; Similar sites found with APoc: 50
This union binding pocket(no: 8) in the query (biounit: 5bsh.bio1) has 33 residues
No: Leader PDB Ligand Sequence Similarity
1 2YIP YIO None
2 3EB9 FLC 1.12782
3 5A96 GTP 1.60643
4 3JUC PCA 1.96078
5 3K5I AIR 2.16606
6 1P7T PYR 2.16606
7 1RRC ADP 2.16606
8 4G5H NAP 2.16606
9 4G5H UD7 2.16606
10 1YB5 NAP 2.16606
11 3NOJ PYR 2.52101
12 1N5D NDP 2.52708
13 5JH2 A2P 2.52708
14 2BGM NAJ 2.88809
15 3RFV 15L 2.99625
16 3RFV NAI 2.99625
17 5ZI9 FLC 3.07692
18 1D8C GLV 3.2491
19 5I7S NAD 3.26087
20 5I7S E9P 3.26087
21 5TQZ GLC 3.33333
22 3ITJ CIT 3.61011
23 5ZEC NAP 3.61011
24 4GLW NMN 3.97112
25 1V35 NAI 3.97112
26 1R0X ATP 3.97112
27 4KFU ACP 4.24528
28 1SKQ GDP 4.33213
29 3Q72 GNP 4.81928
30 1NXJ TLA 4.91803
31 5Z75 NAD 5.05415
32 4B7X NAP 5.05415
33 4NTO 1PW 5.31401
34 1H9A NAP 5.41516
35 2JGV ADP 5.45455
36 3QRC SCR 6.36943
37 5E5U MLI 7.19697
38 3DZD ADP 7.22022
39 5K4W THR 7.58123
40 5K4W NAI 7.58123
41 4KVL PLM 7.94224
42 3S5W FAD 9.02527
43 4R5M 4NO 9.74729
44 1OFS SUC 10.4167
45 4R1S NAP 10.8303
46 1KSK URA 11.1111
47 3W5J GDP 11.2745
48 2GN4 NDP 22.7437
49 2GN4 UD1 22.7437
50 2QN6 GDP 32.2581
Pocket No.: 9; Query (leader) PDB : 5BSH; Ligand: PRO; Similar sites found with APoc: 31
This union binding pocket(no: 9) in the query (biounit: 5bsh.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 2BZG SAH 1.72414
2 1NAA 6FA 2.52708
3 1NAA ABL 2.52708
4 3E5H GNP 2.80899
5 4C25 13P 2.83019
6 3F8D FAD 2.88809
7 1COY FAD 2.88809
8 1COY AND 2.88809
9 5WS9 AMP 3.2491
10 3QJ4 FAD 3.61011
11 1XKQ NDP 3.97112
12 5X40 ACP 3.97112
13 4RF2 NAP 4.77941
14 3X0V FAD 5.05415
15 1RYI FAD 5.41516
16 4HA6 FAD 5.77617
17 4IDN GNP 6.13718
18 2DXU BT5 6.38298
19 4PKI ATP 6.85921
20 5ZZB ATP 6.85921
21 1KXP ATP 6.85921
22 2A42 ATP 6.85921
23 5G3U FDA 9.74729
24 2GAG FAD 10.101
25 4O33 3PG 10.8303
26 4O33 TZN 10.8303
27 4ZOH MCN 11.3095
28 4IV9 FAD 13.3574
29 4YSW FAD 13.7184
30 4YSW NAI 13.7184
31 1NLM UD1 14.8014
Pocket No.: 10; Query (leader) PDB : 5BSH; Ligand: PRO; Similar sites found with APoc: 4
This union binding pocket(no: 10) in the query (biounit: 5bsh.bio1) has 33 residues
No: Leader PDB Ligand Sequence Similarity
1 1TV5 ORO 3.61011
2 5LTJ ADP 5.05415
3 4RGA 3PV 7.22022
4 2XT3 ADP 14.0794
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