Receptor
PDB id Resolution Class Description Source Keywords
5BW4 2.1 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF THE 16S RRNA (ADENINE(1408)-N(1))- METHYLTRANSFERASE W203A MUTANT WITH COSUBSTRATE SAM FROM C ATENULISPORALES ACIDIPHILIA CATENULISPORA ACIDIPHILA METHYLTRANSFERASE RIBOSOME AMINOGLYCOSIDE RESISTANCE TRAN
Ref.: FUNCTIONAL DICHOTOMY IN THE 16S RRNA (M1A1408) METHYLTRANSFERASE FAMILY AND CONTROL OF CATALYTIC A VIA A NOVEL TRYPTOPHAN MEDIATED LOOP REORGANIZATION NUCLEIC ACIDS RES. V. 44 342 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAM A:301;
B:301;
Valid;
Valid;
none;
none;
Kd = 68 uM
398.437 C15 H22 N6 O5 S C[S@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5BW4 2.1 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF THE 16S RRNA (ADENINE(1408)-N(1))- METHYLTRANSFERASE W203A MUTANT WITH COSUBSTRATE SAM FROM C ATENULISPORALES ACIDIPHILIA CATENULISPORA ACIDIPHILA METHYLTRANSFERASE RIBOSOME AMINOGLYCOSIDE RESISTANCE TRAN
Ref.: FUNCTIONAL DICHOTOMY IN THE 16S RRNA (M1A1408) METHYLTRANSFERASE FAMILY AND CONTROL OF CATALYTIC A VIA A NOVEL TRYPTOPHAN MEDIATED LOOP REORGANIZATION NUCLEIC ACIDS RES. V. 44 342 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 236 families.
1 5BW4 Kd = 68 uM SAM C15 H22 N6 O5 S C[S@@+](CC....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 211 families.
1 5BW4 Kd = 68 uM SAM C15 H22 N6 O5 S C[S@@+](CC....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 166 families.
1 5BW4 Kd = 68 uM SAM C15 H22 N6 O5 S C[S@@+](CC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAM; Similar ligands found: 192
No: Ligand ECFP6 Tc MDL keys Tc
1 SAM 1 1
2 SMM 0.792683 0.96
3 S4M 0.6875 0.909091
4 S7M 0.670455 0.945946
5 M2T 0.636364 0.878378
6 GEK 0.612903 0.931507
7 SAI 0.571429 0.878378
8 XYA 0.565789 0.773333
9 ADN 0.565789 0.773333
10 RAB 0.565789 0.773333
11 5CD 0.564103 0.783784
12 EP4 0.5625 0.826667
13 SA8 0.56044 0.945205
14 SFG 0.555556 0.875
15 5X8 0.555556 0.888889
16 5N5 0.551282 0.773333
17 A4D 0.544304 0.797297
18 EEM 0.542553 0.945946
19 SAH 0.537634 0.916667
20 DTA 0.536585 0.789474
21 62X 0.535354 0.884615
22 MTA 0.53012 0.875
23 3DH 0.517647 0.849315
24 AMP MG 0.511364 0.710843
25 5AL 0.510417 0.743902
26 VMS 0.510204 0.673913
27 54H 0.510204 0.673913
28 0UM 0.51 0.857143
29 A 0.505747 0.707317
30 AMP 0.505747 0.707317
31 ABM 0.505618 0.753086
32 A5A 0.505155 0.688889
33 DAL AMP 0.50505 0.765432
34 NVA LMS 0.504951 0.725275
35 K15 0.5 0.883117
36 6RE 0.5 0.78481
37 5AD 0.5 0.75
38 SSA 0.5 0.684783
39 SON 0.5 0.746988
40 SRP 0.5 0.746988
41 LSS 0.49505 0.706522
42 CA0 0.494624 0.714286
43 A12 0.494505 0.705882
44 AP2 0.494505 0.705882
45 ME8 0.490385 0.841463
46 5CA 0.49 0.684783
47 TSB 0.49 0.681319
48 53H 0.49 0.666667
49 ACP 0.489362 0.694118
50 5AS 0.48913 0.648936
51 ADP 0.48913 0.690476
52 A2D 0.488889 0.690476
53 J7C 0.488889 0.772152
54 ZAS 0.488636 0.769231
55 8QN 0.485149 0.743902
56 GAP 0.484536 0.73494
57 AN2 0.483871 0.682353
58 A3S 0.483871 0.813333
59 A7D 0.483871 0.851351
60 GJV 0.483516 0.775
61 SRA 0.483146 0.694118
62 LAD 0.480769 0.752941
63 KAA 0.480769 0.698925
64 GSU 0.480769 0.722222
65 AMO 0.480392 0.746988
66 DSZ 0.480392 0.703297
67 52H 0.48 0.666667
68 ADP MG 0.478723 0.702381
69 M33 0.478723 0.722892
70 MAO 0.478261 0.82716
71 BA3 0.478261 0.690476
72 AOC 0.477778 0.776316
73 DSH 0.477778 0.842105
74 NEC 0.477778 0.75
75 SXZ 0.47619 0.894737
76 AHX 0.475728 0.701149
77 Y3J 0.47561 0.706667
78 G5A 0.474227 0.684783
79 A3T 0.473684 0.8
80 ADP BEF 0.473684 0.686047
81 BEF ADP 0.473684 0.686047
82 B4P 0.473118 0.690476
83 AP5 0.473118 0.690476
84 A3N 0.472527 0.766234
85 KB1 0.471698 0.833333
86 LEU LMS 0.471154 0.706522
87 APC 0.46875 0.705882
88 PRX 0.46875 0.73494
89 PAJ 0.466019 0.712644
90 4AD 0.466019 0.759036
91 RBY 0.463918 0.72619
92 ADP PO3 0.463918 0.728395
93 ADV 0.463918 0.72619
94 ADX 0.463158 0.666667
95 MHZ 0.463158 0.82716
96 AU1 0.463158 0.674419
97 YAP 0.462963 0.738095
98 TXA 0.462264 0.72619
99 NB8 0.462264 0.72093
100 A3G 0.461538 0.802632
101 VRT 0.459184 0.842105
102 ATP MG 0.459184 0.702381
103 YSA 0.458716 0.684783
104 XAH 0.458716 0.715909
105 50T 0.458333 0.682353
106 ATP 0.458333 0.690476
107 7D7 0.45679 0.723684
108 ANP MG 0.455446 0.678161
109 KH3 0.455357 0.871795
110 ACQ 0.454545 0.694118
111 AQP 0.453608 0.690476
112 5FA 0.453608 0.690476
113 AR6 0.453608 0.710843
114 APR 0.453608 0.710843
115 NSS 0.451923 0.703297
116 FA5 0.449541 0.746988
117 AGS 0.44898 0.678161
118 SAP 0.44898 0.678161
119 A5D 0.44898 0.789474
120 AD9 0.44898 0.674419
121 PTJ 0.448598 0.72093
122 YLB 0.448276 0.758621
123 YLP 0.447368 0.738636
124 D3Y 0.446602 0.792208
125 ADP ALF 0.445545 0.678161
126 ALF ADP 0.445545 0.678161
127 TYR AMP 0.445455 0.746988
128 MYR AMP 0.444444 0.776471
129 3AM 0.444444 0.674699
130 OAD 0.443396 0.73494
131 2VA 0.443299 0.779221
132 OOB 0.442308 0.722892
133 S8M 0.442308 0.831169
134 ADP VO4 0.441176 0.702381
135 VO4 ADP 0.441176 0.702381
136 ANP 0.44 0.674419
137 TAT 0.44 0.686047
138 WAQ 0.439252 0.75
139 ARG AMP 0.438596 0.727273
140 YLC 0.435897 0.755814
141 AAT 0.435644 0.797468
142 3OD 0.435185 0.73494
143 1ZZ 0.435185 0.755814
144 NVA 2AD 0.434343 0.815789
145 DLL 0.433962 0.722892
146 00A 0.433962 0.689655
147 7MD 0.433628 0.715909
148 ATF 0.431373 0.666667
149 SO8 0.43 0.792208
150 3UK 0.429907 0.714286
151 A6D 0.429907 0.72619
152 5SV 0.428571 0.741176
153 AMP DBH 0.428571 0.714286
154 WSA 0.42735 0.692308
155 TYM 0.42735 0.746988
156 9SN 0.427273 0.681818
157 AHZ 0.426087 0.755814
158 A A 0.425926 0.710843
159 3NZ 0.425926 0.807692
160 P5A 0.425926 0.691489
161 PR8 0.425926 0.744186
162 A1R 0.424528 0.709302
163 2A5 0.424242 0.674419
164 7MC 0.423729 0.719101
165 7D5 0.422222 0.658824
166 FYA 0.422018 0.722892
167 JB6 0.422018 0.709302
168 AYB 0.421488 0.75
169 PLP AAD 0.419355 0.764045
170 A22 0.419048 0.682353
171 MAP 0.419048 0.659091
172 2AM 0.417582 0.666667
173 TAD 0.417391 0.712644
174 A3P 0.416667 0.686747
175 ADP BMA 0.416667 0.714286
176 25A 0.415094 0.690476
177 YLA 0.413223 0.719101
178 ADQ 0.411215 0.694118
179 48N 0.410256 0.72093
180 0XU 0.41 0.824324
181 NAD IBO 0.406504 0.717647
182 7D3 0.40625 0.643678
183 PAP 0.405941 0.678571
184 OVE 0.404255 0.662791
185 4UV 0.403509 0.697674
186 ALF ADP 3PG 0.403361 0.712644
187 AF3 ADP 3PG 0.403361 0.712644
188 LA8 ALF 3PG 0.403361 0.712644
189 3AD 0.402299 0.783784
190 CMP 0.402062 0.691358
191 2BA 0.402062 0.682927
192 7C5 0.4 0.731707
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5BW4; Ligand: SAM; Similar sites found: 311
This union binding pocket(no: 1) in the query (biounit: 5bw4.bio1) has 20 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1RJD SAM 0.00003704 0.50835 None
2 1QAN SAH 0.00002743 0.47002 None
3 2FKA BEF 0.005445 0.42905 None
4 1L7N ALF 0.01478 0.41114 1.4218
5 1L7N AF3 0.01997 0.40621 1.4218
6 2XVM SAH 0.00000193 0.57152 1.50754
7 5FUI APY 0.009259 0.41501 1.51515
8 5KOK SAH 0.00000122 0.54156 1.87266
9 5JCM NAD 0.0009345 0.4916 1.87266
10 5JCM FAD 0.000904 0.4916 1.87266
11 5JCM ISD 0.0009345 0.4916 1.87266
12 2PT9 2MH 0.0003143 0.48722 1.87266
13 1X7D ORN 0.01067 0.41868 1.87266
14 1X7D NAD 0.006739 0.41866 1.87266
15 3U31 NAD 0.0008114 0.41685 1.87266
16 5KOK S9T 0.00002151 0.40829 1.87266
17 2PT9 S4M 0.0422 0.40262 1.87266
18 1XDS SAM 0.000007526 0.54457 2.24719
19 1QZZ SAM 0.00001309 0.5336 2.24719
20 2YX1 SFG 0.0000183 0.52696 2.24719
21 3A4T SFG 0.000005079 0.50147 2.24719
22 1U2Z SAH 0.00006802 0.50094 2.24719
23 4DMG SAM 0.000155 0.4905 2.24719
24 3NTD FAD 0.0008058 0.47301 2.24719
25 4N49 SAM 0.00027 0.44214 2.24719
26 2V3V MGD 0.01239 0.43867 2.24719
27 1X87 NAD 0.0003049 0.42783 2.24719
28 1X14 NAD 0.002746 0.41939 2.24719
29 1QCI ADE 0.02359 0.40002 2.29008
30 3AFN NAP 0.01939 0.40216 2.32558
31 1QXA GLY GLY GLY 0.01015 0.4108 2.55319
32 2BZG SAH 0.00001749 0.5178 2.58621
33 1V59 NAD 0.00003732 0.5194 2.62172
34 3A25 SAM 0.0000445 0.48843 2.62172
35 2GVC FAD 0.0002886 0.48756 2.62172
36 2YY7 NAD 0.001339 0.45379 2.62172
37 1PS9 FAD 0.002587 0.45213 2.62172
38 1EU1 MGD 0.008676 0.42296 2.62172
39 4PIO AVI 0.00001037 0.41731 2.62172
40 4PIO SAH 0.00001124 0.41141 2.62172
41 3IHG FAD 0.0001539 0.40948 2.62172
42 1YFS ALA 0.01671 0.40426 2.62172
43 4D86 ADP 0.003553 0.40232 2.62172
44 2A14 SAH 0.0001501 0.48349 2.6616
45 4RL4 PPV 0.01608 0.41112 2.83019
46 2AG5 NAD 0.006144 0.42184 2.84553
47 1PR9 NAP 0.002453 0.4442 2.86885
48 2BOS GLA GAL GLC NBU 0.01284 0.41126 2.94118
49 2BOS GLA GAL GLC 0.02722 0.40413 2.94118
50 4RDN 6MD 0.01882 0.40842 2.99401
51 3O7W SAM 0.000009325 0.54032 2.99625
52 2EG5 SAH 0.00001014 0.53867 2.99625
53 5E9W SAH 0.000007927 0.50794 2.99625
54 3ICS FAD 0.0001844 0.50338 2.99625
55 4CNK FAD 0.0003181 0.49215 2.99625
56 4D79 ATP 0.0000691 0.47987 2.99625
57 5FJN FAD 0.001153 0.46997 2.99625
58 5FJN BE2 0.001331 0.46997 2.99625
59 3EVG SAH 0.0001432 0.4666 2.99625
60 2ZWA SAH 0.00005661 0.45839 2.99625
61 1UP7 NAD 0.0008312 0.45566 2.99625
62 2P41 SAH 0.0002736 0.45512 2.99625
63 1FEC FAD 0.003037 0.45353 2.99625
64 3ICT ADP 0.0009627 0.45344 2.99625
65 1BC5 SAH 0.001764 0.43749 2.99625
66 4USQ FAD 0.01657 0.43276 2.99625
67 3L9W GSH 0.00008886 0.41624 2.99625
68 3ICS ADP 0.001468 0.41624 2.99625
69 3L9W AMP 0.00005798 0.41279 2.99625
70 4J7U NAP 0.0202 0.41012 2.99625
71 4J7U YTZ 0.0202 0.41012 2.99625
72 1Z6Z NAP 0.01256 0.40746 2.99625
73 4I54 1C1 0.01717 0.40115 2.99625
74 2DTX BMA 0.02933 0.4249 3.0303
75 3FRH SAH 0.00003538 0.51367 3.16206
76 3VSE SAH 0.000005802 0.55716 3.37079
77 1Z3C SA8 0.00001013 0.55018 3.37079
78 2UYQ SAM 0.00004387 0.54236 3.37079
79 3GDN HBX 0.001119 0.47823 3.37079
80 3GDN FAD 0.0007763 0.47823 3.37079
81 3I53 SAH 0.00002931 0.47733 3.37079
82 3QVP FAD 0.001008 0.47382 3.37079
83 3H8V ATP 0.0001909 0.46251 3.37079
84 2O4C NAD 0.005355 0.42589 3.37079
85 5UAO FAD 0.009055 0.4231 3.37079
86 2PX8 SAH 0.002717 0.41303 3.37079
87 1SC6 NAD 0.01225 0.41038 3.37079
88 2FK8 SAM 0.000007152 0.50083 3.45912
89 4R6W SAH 0.00003261 0.41581 3.48837
90 3FZG SAM 0.00005656 0.4986 3.5
91 1IM8 SAI 0.00002123 0.48302 3.68852
92 5E1M SAH 0.00000181 0.43529 3.73444
93 5E1M PRO PRO LYS ARG ILE ALA 0.00000181 0.43529 3.73444
94 3DMH SAM 0.000009814 0.49773 3.74532
95 2CDU FAD 0.000256 0.49408 3.74532
96 1YXM ADE 0.002301 0.44784 3.74532
97 3DMH GMP 0.00001899 0.4446 3.74532
98 2CDU ADP 0.0008324 0.442 3.74532
99 3NJ4 NAD 0.02895 0.43477 3.74532
100 2DFV NAD 0.003189 0.43219 3.74532
101 1CF2 NAP 0.00529 0.42069 3.74532
102 1G60 SAM 0.00001626 0.49665 3.84615
103 4J4H 1J1 0.01627 0.41804 3.861
104 4J4H NAI 0.01627 0.41804 3.861
105 2JJQ SAH 0.00003032 0.51696 4.11985
106 4AZW SAM 0.0000234 0.51478 4.11985
107 4RDH AMP 0.000041 0.50483 4.11985
108 1NW5 SAM 0.0000646 0.49532 4.11985
109 4TM3 FAD 0.00134 0.4858 4.11985
110 4C3Y FAD 0.0007045 0.47917 4.11985
111 5BUK FAD 0.0008314 0.47886 4.11985
112 4C3Y ANB 0.0009152 0.47881 4.11985
113 4RDI ATP 0.00007381 0.47859 4.11985
114 2WPF FAD 0.004402 0.4711 4.11985
115 3GCZ SAM 0.0001574 0.4649 4.11985
116 2F5Z FAD 0.001554 0.46476 4.11985
117 4ONQ SFG 0.0001786 0.46331 4.11985
118 2PZM NAD 0.002314 0.45643 4.11985
119 2PZM UDP 0.002314 0.45643 4.11985
120 1NV8 MEQ 0.000007248 0.45558 4.11985
121 2WPF WPF 0.009973 0.45389 4.11985
122 1NV8 SAM 0.00000799 0.44801 4.11985
123 5GWX SAR 0.00005699 0.43867 4.11985
124 5GWX SAM 0.00005699 0.43867 4.11985
125 1ZMD NAI 0.0001465 0.42831 4.11985
126 5XLX SAH 0.00234 0.42451 4.11985
127 4BLW SAH 0.0002363 0.4165 4.11985
128 5O4J SAH 0.01127 0.41436 4.11985
129 5O4J 9KH 0.01127 0.41436 4.11985
130 5O4J PJL 0.01185 0.4122 4.11985
131 1OBB NAD 0.0004518 0.41014 4.11985
132 4XUC 43G 0.0001029 0.50993 4.12844
133 4XUC SAM 0.0001029 0.50993 4.12844
134 3WV8 ATP 0.00001272 0.50047 4.12844
135 3VC1 SAH 0.00001575 0.47554 4.16667
136 3VC1 GST 0.00003517 0.40045 4.16667
137 1JG3 ADN 0.00002547 0.49847 4.25532
138 1LSS NAD 0.00005754 0.46741 4.28571
139 5FA5 MTA 0.000005747 0.54286 4.49438
140 4MIG G3F 0.002166 0.46245 4.49438
141 2XVE FAD 0.00354 0.4598 4.49438
142 3VYW SAM 0.0001887 0.44759 4.49438
143 3GRU AMP 0.0001005 0.44724 4.49438
144 5A7Y SAH 0.01211 0.40595 4.49438
145 5KJW 53C 0.02043 0.40567 4.49438
146 5E8J SAH 0.000008944 0.54114 4.54545
147 3DXY SAM 0.000000242 0.62162 4.58716
148 3BGD SAH 0.00001843 0.47262 4.61538
149 3BGD PM6 0.00002635 0.44166 4.61538
150 3C3Y SAH 0.003238 0.42028 4.64135
151 2PXX SAH 0.000001155 0.54196 4.65116
152 3OID NDP 0.003892 0.43484 4.65116
153 4MBY BGC SIA GAL 0.01473 0.41045 4.67626
154 1JQ3 AAT 0.00003508 0.40945 4.72973
155 1WY7 SAH 0.000779 0.41522 4.83092
156 2EJU SAH 0.000005432 0.52629 4.86891
157 1QO8 FAD 0.000161 0.51102 4.86891
158 3PT9 SAH 0.00002388 0.49914 4.86891
159 4II2 ATP 0.000009932 0.49592 4.86891
160 5DX8 SFG 0.00001815 0.47045 4.86891
161 1ZQ9 SAM 0.0001252 0.46983 4.86891
162 5DXA SFG 0.00001928 0.46969 4.86891
163 5DX1 SFG 0.0000102 0.46296 4.86891
164 1AE1 NAP 0.002594 0.44306 4.86891
165 1DJN ADP 0.0008681 0.41018 4.86891
166 1O94 ADP 0.0007765 0.4066 4.86891
167 1Q0S SAH 0.00003429 0.51638 5.01931
168 4NYT PC 0.005822 0.42283 5.06912
169 2NXE SAM 0.00002099 0.50158 5.11811
170 4QTU SAM 0.000001749 0.53562 5.18518
171 3G89 SAM 0.000000008808 0.67829 5.22088
172 4IWN GEK 0.00001105 0.4782 5.24017
173 1G55 SAH 0.00000217 0.53048 5.24345
174 3QOX SAH 0.00002402 0.52122 5.24345
175 3A27 SAM 0.00003707 0.49158 5.24345
176 2VVM FAD 0.001211 0.46684 5.24345
177 3Q87 SAM 0.00008764 0.44273 5.24345
178 4FC7 NAP 0.007853 0.42993 5.24345
179 4FC7 COA 0.007853 0.42993 5.24345
180 3CIF NAD 0.004201 0.42811 5.24345
181 3CIF G3H 0.00638 0.42711 5.24345
182 5MW4 5JU 0.00002166 0.41601 5.24345
183 3IT7 TLA 0.008747 0.42795 5.49451
184 3CH6 NAP 0.001889 0.47414 5.59441
185 3CH6 311 0.001889 0.47414 5.59441
186 5X62 SAH 0.00001081 0.52421 5.61798
187 4J36 1HR 0.0002506 0.50291 5.61798
188 2ZIF SAM 0.0000143 0.50005 5.61798
189 4J36 FAD 0.0001729 0.49794 5.61798
190 1KPG SAH 0.000005832 0.49511 5.61798
191 3C6K SPD 0.0006829 0.474 5.61798
192 3C6K MTA 0.0006829 0.474 5.61798
193 4DCM SAM 0.0001898 0.4637 5.61798
194 5AYV NAP 0.006552 0.41188 5.61798
195 4M38 SAH 0.000007306 0.50251 5.99251
196 1L1E SAH 0.000007092 0.5014 5.99251
197 5EB4 FAD 0.0005193 0.48439 5.99251
198 4FZV SAM 0.00003194 0.47863 5.99251
199 5THY SAH 0.00003505 0.47728 5.99251
200 5THQ NDP 0.007005 0.4192 5.99251
201 5AHO TLA 0.008737 0.41477 5.99251
202 1R18 SAH 0.00002956 0.46816 6.1674
203 2PWY SAH 0.004345 0.44853 6.20155
204 1WG8 SAM 0.00001495 0.53264 6.36704
205 1TPY SAH 0.000005852 0.49476 6.36704
206 5JJR SAH 0.0003144 0.45253 6.36704
207 2B9W FAD 0.02517 0.41455 6.36704
208 2XYQ SAH 0.003033 0.41208 6.55738
209 5OFW 9TW 0.001856 0.45954 6.72646
210 3DUW SAH 0.001689 0.43276 6.72646
211 3X0D SAH 0.000002966 0.55436 6.74157
212 4Y2H SAH 0.00002967 0.54237 6.74157
213 4Y2H 49K 0.000046 0.53331 6.74157
214 1KPH SAH 0.000007806 0.49072 6.74157
215 2E5V FAD 0.00049 0.48889 6.74157
216 1XSE NDP 0.004763 0.43843 6.74157
217 2DPM SAM 0.0002796 0.43441 6.74157
218 2O07 MTA 0.0001026 0.41742 6.74157
219 2O07 SPD 0.0001215 0.4048 6.74157
220 3Q9N COA 0.01371 0.40177 6.96203
221 4OBW SAM 0.00004185 0.48952 7.00389
222 5XVK SAH 0.0001583 0.44054 7.04225
223 3G2O SAM 0.000003596 0.5339 7.11611
224 1GET NAP 0.002342 0.47355 7.11611
225 1GET FAD 0.002205 0.47355 7.11611
226 1V8B NAD 0.01003 0.41891 7.11611
227 3M6W SAM 0.00413 0.41551 7.11611
228 3JUC PCA 0.01105 0.41326 7.18954
229 3GU3 SAH 0.000001722 0.59033 7.39437
230 3OFK SAH 0.00008739 0.45129 7.40741
231 3EGV SAH 0.00001934 0.5132 7.48299
232 1DL5 SAH 0.0003674 0.40979 7.49064
233 5F7J ADE 0.02217 0.4044 7.49064
234 5L95 AMP 0.0001572 0.45815 7.5
235 3GWZ SAH 0.00006758 0.50108 7.58808
236 3GXO SAH 0.0002153 0.47272 7.58808
237 5N53 8NB 0.0002891 0.50062 7.69231
238 5MPT SAH 0.00002289 0.5005 7.86517
239 3TLJ SAH 0.000006317 0.48745 7.86517
240 1J0X NAD 0.003865 0.4457 7.86517
241 2PHX MAN MAN 0.008549 0.42383 7.93651
242 1UKG MMA 0.007365 0.4234 7.93651
243 2GND MAN 0.01168 0.41561 7.93651
244 1Q8Q MAN MMA 0.01375 0.41361 7.93651
245 2GNB MAN 0.01618 0.40618 7.93651
246 1Q8S MAN MMA 0.01755 0.40601 7.93651
247 2GNM MAN 0.02052 0.4032 7.93651
248 2GN3 MMA 0.01242 0.40301 7.93651
249 2IVF MGD 0.01506 0.41256 7.94393
250 1NFQ NAI 0.007103 0.42143 8.07692
251 5FTW SAH 0.0003238 0.43782 8.20312
252 4C4A SAH 0.000003079 0.55365 8.2397
253 1ELI PYC 0.00005312 0.52902 8.2397
254 1KYQ NAD 0.0001349 0.47645 8.2397
255 4LH7 1X8 0.01745 0.40738 8.2397
256 4GLL NAD 0.01794 0.40262 8.2397
257 3GDH SAH 0.000005621 0.48198 8.29876
258 2WA2 SAM 0.001077 0.43713 8.33333
259 3FUU ADN 0.000008765 0.50876 8.48709
260 4POO SAM 0.0000474 0.51004 8.5
261 3GEG NAD 0.02604 0.41577 8.50202
262 3UCL CYH 0.000443 0.50787 8.61423
263 3UCL FAD 0.000443 0.50787 8.61423
264 3UCL NAP 0.0004895 0.50787 8.61423
265 4BV6 FAD 0.000347 0.49389 8.61423
266 1Y8Q ATP 0.000002317 0.49261 8.61423
267 1I1N SAH 0.00004084 0.43229 9.29204
268 5MGZ SAH 0.00001213 0.50288 9.32203
269 1JNR FAD 0.003284 0.46921 9.33333
270 4CS9 AMP 0.01638 0.40484 9.52381
271 5CUQ NSC 0.0001815 0.49548 9.73783
272 2AOT SAH 0.0000008462 0.57994 10.1124
273 1KYZ SAH 0.00001969 0.51286 10.1124
274 1JQD SAH 0.00000487 0.44434 10.1124
275 1JQD HSM 0.00002318 0.44217 10.1124
276 3LCC SAH 0.0000006089 0.57866 10.2128
277 4XBA GMP 0.006352 0.4151 10.4869
278 1N4W FAD 0.000284 0.50029 10.7143
279 5THZ SAH 0.00006967 0.50047 10.8614
280 4UP3 FAD 0.003473 0.44498 10.8614
281 5DM1 SAH 0.0000002777 0.4316 10.8614
282 5DM1 5D7 0.0000003009 0.42596 10.8614
283 2QQF A1R 0.007061 0.41351 10.8614
284 1EJ0 SAM 0.00006922 0.4916 11.1111
285 2VT3 ATP 0.001191 0.44912 11.1628
286 4M73 SAH 0.000001771 0.42689 11.236
287 4M73 M72 0.000002366 0.41868 11.236
288 1S7G NAD 0.003924 0.43215 11.4625
289 1S7G APR 0.005247 0.42877 11.4625
290 3TKY SAH 0.0000548 0.49847 11.6105
291 3S5W FAD 0.0001296 0.40211 11.6105
292 1E6E FAD 0.0003813 0.48592 11.985
293 3S1S SAH 0.00004009 0.45587 11.985
294 4XFR CIT 0.01432 0.41154 11.985
295 5DLY SAH 0.00000784 0.40645 12.0301
296 2WSB NAD 0.001957 0.45689 12.2047
297 1N2X SAM 0.00001411 0.47411 12.7341
298 3CGD FAD 0.001212 0.49309 13.8577
299 3CGD COA 0.001212 0.49309 13.8577
300 3CGD NAD 0.001212 0.49309 13.8577
301 5TVF CGQ 0.01759 0.40219 14.1176
302 1P1C SAH 0.00002208 0.47034 15.0754
303 3JWH SAH 0.0000001402 0.57542 15.6682
304 2VDV SAM 0.0000000579 0.64099 16.2602
305 3EGI ADP 0.000007077 0.57811 16.9903
306 5HJM MTA 0.00008621 0.46796 17.9775
307 2FAV APR 0.008498 0.40984 18.3333
308 5M58 SAH 0.0001154 0.4842 19.1304
309 5DX0 SFG 0.000009284 0.5441 20
310 5DWQ SFG 0.00001119 0.53831 20
311 1VE3 SAM 0.00002197 0.50126 21.5859
Pocket No.: 2; Query (leader) PDB : 5BW4; Ligand: SAM; Similar sites found: 53
This union binding pocket(no: 2) in the query (biounit: 5bw4.bio2) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2CBZ ATP 0.003414 0.45124 1.26582
2 3KU0 ADE 0.02039 0.4106 1.59363
3 2I7C AAT 0.0001763 0.40286 1.87266
4 2VVG ADP 0.02782 0.40029 2.24719
5 4NBW NAD 0.001621 0.40076 2.33463
6 2B6N ALA PRO THR 0.00334 0.44684 2.62172
7 3FPF MTA 0.0000215 0.4081 2.62172
8 3FPF TNA 0.0000215 0.4081 2.62172
9 4B47 GDP 0.02462 0.40167 2.62172
10 2QES ADE 0.02019 0.41045 2.68199
11 3NZ1 3NY 0.02832 0.40837 2.68199
12 1OSS BEN 0.02212 0.40823 2.69058
13 4BQS ADP 0.03146 0.40024 2.84091
14 2AWN ADP 0.006637 0.43331 2.99625
15 2AF6 BRU 0.01228 0.42333 3.10078
16 1O5I NAD 0.00308 0.41751 3.21285
17 3OJO NAD 0.004026 0.40062 3.37079
18 2AJH MET 0.01843 0.4116 3.57143
19 3NUG NAD 0.0006065 0.4023 3.74532
20 2XT3 ADP 0.03057 0.40006 3.74532
21 3DC4 ADP 0.01937 0.41123 3.77907
22 2DT5 NAD 0.0007888 0.40285 3.79147
23 5ITV NAI 0.0003626 0.41377 3.92157
24 5LTJ ADP 0.007149 0.42 4.11985
25 5JE8 NAD 0.00247 0.40934 4.11985
26 4BLW AMP 0.0001471 0.40709 4.11985
27 4IEE AGS 0.02131 0.40486 4.11985
28 3IWD M2T 0.009353 0.42764 4.41176
29 4J1Q NDP 0.005835 0.40701 4.49438
30 3HVJ 705 0.00001039 0.42899 4.52489
31 1G6H ADP 0.0112 0.42815 4.66926
32 5GJC ATP 0.009187 0.41892 4.86891
33 4DSU BZI 0.0252 0.40936 5.29101
34 1JJ7 ADP 0.01091 0.42815 5.76923
35 3H4S ADP 0.01956 0.41199 5.92593
36 1V8K ANP 0.01095 0.41517 5.99251
37 3WY9 GDP 0.02224 0.40391 5.99251
38 1N13 AG2 0.03038 0.40353 6.19469
39 1SKQ GDP 0.02318 0.403 6.36704
40 4OX5 DAL 0.02379 0.40745 6.41711
41 5K7U SAM 0.005352 0.41061 6.74157
42 5IL1 SAM 0.006288 0.40755 6.74157
43 2XG5 EC2 0.03107 0.40062 6.93642
44 2XG5 EC5 0.03107 0.40062 6.93642
45 2YIP YIO 0.02374 0.40422 7.24638
46 2WHX ADP 0.004931 0.44409 7.49064
47 2PHT MAN MAN MAN 0.01839 0.4134 7.93651
48 3H0L ADP 0.01855 0.4079 8.98876
49 5E5U MLI 0.002651 0.43897 12.0603
50 2HT6 GDP 0.0255 0.4009 12.069
51 1XCL SAH 0.00007051 0.42711 12.766
52 2QN6 GDP 0.02245 0.40371 13.9785
53 5D4V SAH 0.004902 0.40245 23.97
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