Receptor
PDB id Resolution Class Description Source Keywords
5C3K 2.02 Å EC: 6.3.2.- FRAGMENT-BASED DRUG DISCOVERY TARGETING INHIBITOR OF APOPTOS PROTEINS: COMPOUND 4 HOMO SAPIENS LIGASE APOPTOSIS
Ref.: FRAGMENT-BASED DRUG DISCOVERY TARGETING INHIBITOR O APOPTOSIS PROTEINS: DISCOVERY OF A NON-ALANINE LEAD WITH DUAL ACTIVITY AGAINST CIAP1 AND XIAP. J.MED.CHEM. V. 58 6574 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ZN A:401;
 Part of Protein;
 none;
 submit data
65.409 Zn [Zn+2...
4XF A:402;
 Valid;
 none;
 ic50 = 110 uM
181.215 C8 H13 N4 O C[C@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5C83 2.33 Å EC: 6.3.2.- FRAGMENT-BASED DRUG DISCOVERY TARGETING INHIBITOR OF APOPTOS PROTEINS: COMPOUND 21 HOMO SAPIENS LIGASE APOPTOSIS
Ref.: FRAGMENT-BASED DRUG DISCOVERY TARGETING INHIBITOR O APOPTOSIS PROTEINS: DISCOVERY OF A NON-ALANINE LEAD WITH DUAL ACTIVITY AGAINST CIAP1 AND XIAP. J.MED.CHEM. V. 58 6574 2015
Members (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 41 families.
1 5C7A - 4YE C15 H22 N3 O C[C@@H]1CN....
2 5C3K ic50 = 110 uM 4XF C8 H13 N4 O C[C@@H](C(....
3 5C7D ic50 = 7.7 uM 4YF C14 H20 Cl N4 O C[C@@H]1CN....
4 5C83 ic50 = 0.16 uM 4YN C25 H35 N4 O2 C[C@@H]1CN....
5 5C84 ic50 = 0.64 uM 4YL C18 H28 Cl N4 O2 C[C@@H]1CN....
6 5C0K ic50 = 1200 uM 4WK C8 H18 N3 O2 C[C@@H](C(....
7 5C7C ic50 = 5.5 uM 4YC C17 H25 Cl N3 O C[C@@H]1CN....
70% Homology Family (17)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 5OQW ic50 < 40 nM A4E C30 H43 F N5 O3 C[C@@H]1CN....
2 6H6R - FUE C32 H36 F N5 O2 C[C@@H]1CN....
3 5M6E - 7HT C28 H37 N6 O Cc1cnn(c1)....
4 5M6F ic50 = 220 nM 7HU C25 H35 N4 O2 C[C@@H]1CN....
5 5M6M ic50 = 44 nM 7H8 C28 H38 N5 O2 C[C@@H]1CN....
6 5M6H ic50 = 150 nM 7J6 C28 H38 N5 O3 C[C@@H]1CN....
7 3HL5 - 9JZ C28 H38 N6 O3 C[C@H]1CCN....
8 2VSL Ki = 4 nM MAA LYS PRO PHE n/a n/a
9 1XB0 - ALA VAL PRO ILE ALA GLN LYS n/a n/a
10 3CM2 Ki = 340 nM X23 C28 H37 N5 O3 CC[C@@H](C....
11 5C7A - 4YE C15 H22 N3 O C[C@@H]1CN....
12 5C3K ic50 = 110 uM 4XF C8 H13 N4 O C[C@@H](C(....
13 5C7D ic50 = 7.7 uM 4YF C14 H20 Cl N4 O C[C@@H]1CN....
14 5C83 ic50 = 0.16 uM 4YN C25 H35 N4 O2 C[C@@H]1CN....
15 5C84 ic50 = 0.64 uM 4YL C18 H28 Cl N4 O2 C[C@@H]1CN....
16 5C0K ic50 = 1200 uM 4WK C8 H18 N3 O2 C[C@@H](C(....
17 5C7C ic50 = 5.5 uM 4YC C17 H25 Cl N3 O C[C@@H]1CN....
50% Homology Family (36)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 21 families.
1 4KJU ic50 = 0.006 uM 1RH C32 H33 N5 O4 C[C@@H](C(....
2 4KJV ic50 = 0.018 uM 1RK C30 H33 N3 O7 C[C@@H](C(....
3 4J48 Ki = 2.41 uM ALA MET ARG VAL n/a n/a
4 4J45 Ki = 1.7 uM ALA THR ALA ALA n/a n/a
5 4J46 Ki = 5.24 uM ALA VAL PRO ILE n/a n/a
6 4J47 Ki = 12.02 uM SER VAL PRO ILE n/a n/a
7 4J44 Ki = 1.87 uM ALA ILE ALA VAL n/a n/a
8 4HY5 ic50 = 1.3 nM 1AQ C31 H45 F2 N5 O5 CCO[C@@H]1....
9 4MTI ic50 = 1.2 nM 2DX C30 H45 N5 O4 CC[C@@H](C....
10 4LGU ic50 = 2.1 nM 1YH C29 H43 N5 O4 C[C@@H](C(....
11 3F7G - 389 C27 H36 N4 O3 C[C@@H](C(....
12 3D9T Kd = 48 nM ALA THR PRO PHE GLN GLU n/a n/a
13 5M6N - 7H9 C29 H41 F N5 O2 C[C@@H]1CN....
14 5M6E - 7HT C28 H37 N6 O Cc1cnn(c1)....
15 5M6F ic50 = 220 nM 7HU C25 H35 N4 O2 C[C@@H]1CN....
16 5M6M ic50 = 44 nM 7H8 C28 H38 N5 O2 C[C@@H]1CN....
17 5M6H ic50 = 150 nM 7J6 C28 H38 N5 O3 C[C@@H]1CN....
18 3HL5 - 9JZ C28 H38 N6 O3 C[C@H]1CCN....
19 2VSL Ki = 4 nM MAA LYS PRO PHE n/a n/a
20 3GTA - 851 C29 H36 N4 O2 S C[C@@H](C(....
21 3GT9 - 516 C29 H36 N4 O2 S C[C@@H](C(....
22 2I3I Ki = 0.05 uM 618 C25 H32 N6 O3 S Cc1cc(n(n1....
23 3F7I - G13 C28 H38 N4 O3 C[C@@H](C(....
24 1XB0 - ALA VAL PRO ILE ALA GLN LYS n/a n/a
25 3CM2 Ki = 340 nM X23 C28 H37 N5 O3 CC[C@@H](C....
26 4WVU ic50 = 1.97 uM MAA VAL 3V8 PHE HOX n/a n/a
27 4WVT ic50 = 4.87 uM MAA PHE PRO PHE PHE 3V7 n/a n/a
28 4WVS ic50 = 0.54 uM MAA LPH PRO PHE 4LZ n/a n/a
29 5C7A - 4YE C15 H22 N3 O C[C@@H]1CN....
30 5C3K ic50 = 110 uM 4XF C8 H13 N4 O C[C@@H](C(....
31 5C7D ic50 = 7.7 uM 4YF C14 H20 Cl N4 O C[C@@H]1CN....
32 5C83 ic50 = 0.16 uM 4YN C25 H35 N4 O2 C[C@@H]1CN....
33 5C84 ic50 = 0.64 uM 4YL C18 H28 Cl N4 O2 C[C@@H]1CN....
34 5C0K ic50 = 1200 uM 4WK C8 H18 N3 O2 C[C@@H](C(....
35 5C7C ic50 = 5.5 uM 4YC C17 H25 Cl N3 O C[C@@H]1CN....
36 3UW4 Ki = 0.017 uM MAA CHG PRO 0DQ n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 4XF; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 4XF 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: 4XF; Similar ligands found: 673
No: Ligand Similarity coefficient
1 P80 0.9667
2 PPY 0.9634
3 Y3L 0.9500
4 XDK 0.9493
5 4LW 0.9492
6 R20 0.9479
7 GO2 0.9479
8 TMG 0.9478
9 L22 0.9472
10 R2P 0.9449
11 4LV 0.9431
12 3VX 0.9420
13 HX4 0.9419
14 XCG 0.9412
15 HFA 0.9389
16 MPV 0.9386
17 X48 0.9370
18 BZE 0.9364
19 2FX 0.9360
20 IWT 0.9346
21 6TZ 0.9346
22 4V2 0.9346
23 4BY 0.9341
24 6Q3 0.9337
25 HQJ 0.9334
26 NFA 0.9332
27 M1Z 0.9330
28 1A7 0.9328
29 ENO 0.9327
30 HCI 0.9326
31 DHC 0.9324
32 TCA 0.9316
33 N91 0.9300
34 ESX 0.9297
35 6FB 0.9288
36 PHE 0.9287
37 L5V 0.9287
38 BP7 0.9286
39 56D 0.9283
40 CXH 0.9280
41 A5E 0.9277
42 D3G 0.9270
43 8NB 0.9269
44 J6W 0.9264
45 92G 0.9262
46 1L5 0.9262
47 BZ2 0.9252
48 DAH 0.9251
49 F4E 0.9249
50 E7S 0.9241
51 B40 0.9238
52 6FZ 0.9234
53 X0U 0.9221
54 PO6 0.9221
55 428 0.9219
56 HIS 0.9211
57 ESP 0.9210
58 HC4 0.9210
59 HA5 0.9208
60 5GT 0.9208
61 TRP 0.9206
62 CK2 0.9206
63 J9N 0.9205
64 3ZB 0.9205
65 BNL 0.9198
66 78Y 0.9196
67 363 0.9192
68 XIZ 0.9190
69 MUK 0.9188
70 EVF 0.9188
71 A5H 0.9185
72 LSQ 0.9184
73 1Z6 0.9181
74 X11 0.9181
75 BPY 0.9178
76 JP2 0.9178
77 7VP 0.9176
78 15N 0.9175
79 0NX 0.9171
80 795 0.9171
81 TYL 0.9170
82 ALE 0.9169
83 TT4 0.9168
84 8ZE 0.9160
85 1F1 0.9152
86 BVA 0.9148
87 BZJ 0.9146
88 GZ2 0.9144
89 0JD 0.9142
90 ICB 0.9138
91 6NT 0.9137
92 6KT 0.9136
93 2ZM 0.9136
94 PIM 0.9133
95 MAJ 0.9133
96 PCS 0.9132
97 61M 0.9130
98 GO8 0.9128
99 2BG 0.9126
100 MSR 0.9125
101 YZM 0.9124
102 QIV 0.9115
103 2F6 0.9115
104 PBN 0.9114
105 0HN 0.9113
106 RKV 0.9113
107 G14 0.9110
108 TYR 0.9107
109 6NI 0.9107
110 M3E 0.9105
111 BGU 0.9102
112 AOT 0.9097
113 ESI 0.9097
114 PPT 0.9096
115 6N4 0.9094
116 RNO 0.9093
117 9ZE 0.9090
118 SRO 0.9090
119 SKF 0.9088
120 3NY 0.9086
121 5F8 0.9085
122 PBA 0.9084
123 S2P 0.9079
124 A29 0.9078
125 36M 0.9078
126 JB8 0.9077
127 KTJ 0.9076
128 IAC 0.9075
129 4I8 0.9074
130 XDE 0.9073
131 FZM 0.9071
132 LTN 0.9071
133 4WL 0.9070
134 5FL 0.9070
135 XQI 0.9065
136 AX3 0.9065
137 JDN 0.9064
138 1PS 0.9063
139 SHI 0.9061
140 0SY 0.9061
141 4FF 0.9058
142 N2I 0.9058
143 5RP 0.9058
144 E3X 0.9057
145 492 0.9054
146 HRM 0.9052
147 0HO 0.9051
148 BQ2 0.9050
149 FHC 0.9049
150 PIY 0.9047
151 4MB 0.9047
152 SNO 0.9047
153 0F9 0.9046
154 2D2 0.9045
155 8NX 0.9044
156 CXP 0.9043
157 P81 0.9040
158 SLS 0.9039
159 AJG 0.9038
160 MXD 0.9038
161 FER 0.9036
162 XIY 0.9036
163 CPZ 0.9034
164 KTW 0.9033
165 I2E 0.9030
166 FUD 0.9028
167 FHV 0.9027
168 TZM 0.9026
169 CH9 0.9025
170 EN1 0.9021
171 1M2 0.9021
172 EQW 0.9020
173 FF2 0.9020
174 C82 0.9019
175 KYN 0.9018
176 N9J 0.9018
177 B41 0.9016
178 FCD 0.9015
179 P7Y 0.9014
180 B21 0.9013
181 0BP 0.9010
182 PLP 0.9008
183 3A9 0.9008
184 DE3 0.9007
185 9BF 0.9006
186 TJM 0.9004
187 SNU 0.9003
188 JMG 0.9002
189 5LA 0.9002
190 AMQ 0.8999
191 XI7 0.8999
192 36Y 0.8999
193 AKG 0.8999
194 ZZA 0.8999
195 VM1 0.8998
196 GVG 0.8996
197 4ZA 0.8996
198 URO 0.8996
199 RA7 0.8995
200 PJW 0.8993
201 PRL 0.8992
202 GVY 0.8992
203 3R4 0.8992
204 GOE 0.8991
205 DE5 0.8991
206 EXD 0.8990
207 YPN 0.8990
208 YOF 0.8989
209 HIC 0.8989
210 A5P 0.8989
211 4BL 0.8988
212 K4V 0.8986
213 CIY 0.8986
214 9FL 0.8986
215 PNZ 0.8984
216 PHU 0.8984
217 36E 0.8984
218 15E 0.8983
219 C53 0.8982
220 YIE 0.8982
221 5F5 0.8979
222 JGB 0.8978
223 IOP 0.8978
224 LJ3 0.8975
225 YIP 0.8975
226 UNJ 0.8975
227 9UL 0.8975
228 JAH 0.8974
229 5GU 0.8974
230 6ZW 0.8973
231 2O6 0.8972
232 4VY 0.8970
233 HSO 0.8970
234 KJU 0.8970
235 AMR 0.8968
236 PUE 0.8968
237 P9E 0.8967
238 R9Y 0.8967
239 55D 0.8966
240 N7I 0.8966
241 3VQ 0.8965
242 6MW 0.8965
243 QUS 0.8964
244 PH3 0.8963
245 VXX 0.8963
246 JCZ 0.8962
247 D2G 0.8962
248 YTX 0.8959
249 4P5 0.8959
250 M3H 0.8956
251 KMY 0.8955
252 DTY 0.8952
253 LEL 0.8952
254 GJK 0.8952
255 CFI 0.8951
256 E1T 0.8950
257 NYL 0.8949
258 W29 0.8949
259 5NI 0.8948
260 ZRK 0.8948
261 069 0.8948
262 GJP 0.8947
263 HL4 0.8946
264 8XL 0.8946
265 JND 0.8942
266 2HC 0.8940
267 J9T 0.8940
268 HJH 0.8939
269 RP3 0.8939
270 TU0 0.8939
271 RCV 0.8938
272 ARG 0.8937
273 HJ7 0.8937
274 ODK 0.8935
275 52C 0.8934
276 NCT 0.8934
277 N3W 0.8931
278 KTA 0.8931
279 4NP 0.8931
280 ISZ 0.8931
281 5E5 0.8928
282 Q04 0.8928
283 HSX 0.8928
284 BIK 0.8927
285 IYR 0.8922
286 K7M 0.8920
287 30G 0.8920
288 268 0.8920
289 STT 0.8919
290 FK8 0.8918
291 4G2 0.8918
292 AHN 0.8917
293 TYC 0.8916
294 8WO 0.8916
295 3Y7 0.8915
296 OTR 0.8912
297 7MX 0.8910
298 V1T 0.8909
299 4RU 0.8907
300 94W 0.8906
301 0UL 0.8905
302 4Z3 0.8904
303 3D8 0.8904
304 BNF 0.8903
305 9R5 0.8902
306 L99 0.8902
307 4Z9 0.8902
308 7O4 0.8901
309 LNR 0.8900
310 TYE 0.8898
311 50C 0.8896
312 0W1 0.8896
313 YE6 0.8895
314 2QC 0.8895
315 5B2 0.8894
316 L03 0.8893
317 LDP 0.8892
318 HBO 0.8891
319 N2M 0.8890
320 H4E 0.8890
321 AN3 0.8888
322 4BX 0.8887
323 OGA 0.8885
324 TIH 0.8885
325 12T 0.8883
326 1FE 0.8882
327 UN1 0.8882
328 97T 0.8880
329 BHO 0.8877
330 LQ2 0.8876
331 NIZ 0.8875
332 27B 0.8874
333 258 0.8874
334 SOJ 0.8873
335 HPP 0.8873
336 3SU 0.8873
337 3YP 0.8872
338 6ZX 0.8872
339 0LO 0.8871
340 JOV 0.8869
341 F4K 0.8869
342 PAC 0.8867
343 EWG 0.8867
344 S60 0.8866
345 S0D 0.8865
346 4GU 0.8864
347 4NS 0.8863
348 344 0.8862
349 EYJ 0.8861
350 8D6 0.8861
351 KDV 0.8860
352 ANN 0.8860
353 14W 0.8858
354 CCV 0.8858
355 B4O 0.8857
356 1X4 0.8857
357 IOS 0.8857
358 68A 0.8857
359 S0E 0.8856
360 A7Q 0.8855
361 5XC 0.8854
362 ONR 0.8853
363 0FK 0.8850
364 6J5 0.8850
365 TPA 0.8848
366 7MW 0.8848
367 HNL 0.8847
368 AUV 0.8847
369 FTV 0.8847
370 JRB 0.8846
371 TB8 0.8846
372 HNK 0.8845
373 PNP 0.8845
374 EV0 0.8845
375 HDH 0.8843
376 833 0.8842
377 JG8 0.8842
378 ZHA 0.8842
379 TZF 0.8840
380 DEW 0.8840
381 B1J 0.8839
382 28B 0.8838
383 ZEC 0.8835
384 GZL 0.8834
385 G6P 0.8833
386 NFZ 0.8833
387 CWJ 0.8833
388 BPN 0.8832
389 ABI 0.8830
390 4TB 0.8830
391 D8Q 0.8830
392 EYV 0.8829
393 Z70 0.8829
394 9FE 0.8829
395 NAG 0.8829
396 3C5 0.8828
397 1VK 0.8828
398 1AJ 0.8827
399 M45 0.8827
400 ABF 0.8826
401 KLS 0.8825
402 SG2 0.8825
403 SWX 0.8825
404 C4E 0.8823
405 FBM 0.8822
406 6SD 0.8821
407 EGR 0.8818
408 3AE 0.8818
409 M3P 0.8817
410 PRA 0.8814
411 6C9 0.8814
412 45L 0.8814
413 28A 0.8814
414 K80 0.8810
415 ZME 0.8810
416 LL1 0.8810
417 3C4 0.8809
418 ES2 0.8809
419 5TZ 0.8809
420 2JX 0.8809
421 CKA 0.8807
422 TSS 0.8806
423 2UD 0.8806
424 SSY 0.8804
425 1XS 0.8804
426 8U3 0.8803
427 6RQ 0.8802
428 5VL 0.8802
429 GF4 0.8801
430 PFF 0.8800
431 C0H 0.8799
432 TOH 0.8796
433 7ZL 0.8796
434 MP5 0.8795
435 DHI 0.8795
436 KWB 0.8794
437 5GV 0.8793
438 LR5 0.8793
439 QMP 0.8793
440 HGA 0.8793
441 DPN 0.8793
442 LZ5 0.8792
443 TCR 0.8791
444 DHR 0.8789
445 9CA 0.8789
446 4FP 0.8788
447 4HB 0.8788
448 BRH 0.8787
449 CSN 0.8787
450 AHC 0.8785
451 92P 0.8783
452 EUE 0.8783
453 ZEA 0.8783
454 MD6 0.8782
455 M4T 0.8781
456 7ME 0.8779
457 3TC 0.8779
458 CFA 0.8778
459 I3E 0.8778
460 2BX 0.8777
461 SQ4 0.8777
462 7MU 0.8775
463 ASC 0.8774
464 VGD 0.8773
465 8WT 0.8773
466 27K 0.8773
467 JPQ 0.8773
468 TIA 0.8772
469 7R4 0.8771
470 J9Q 0.8768
471 EV2 0.8767
472 AY4 0.8767
473 LGT 0.8766
474 5O6 0.8765
475 6HP 0.8763
476 HHH 0.8760
477 SQ7 0.8757
478 EQA 0.8756
479 MR1 0.8756
480 BBY 0.8754
481 3VW 0.8753
482 BZQ 0.8752
483 KDG 0.8751
484 PZI 0.8751
485 S7J 0.8750
486 C0W 0.8749
487 1BN 0.8746
488 6HO 0.8745
489 OOG 0.8745
490 1IT 0.8744
491 GCO 0.8743
492 CK1 0.8743
493 ITE 0.8743
494 ZIP 0.8742
495 D48 0.8741
496 6C8 0.8741
497 8W9 0.8741
498 6QF 0.8741
499 CTE 0.8741
500 1QP 0.8741
501 BZ3 0.8739
502 X0W 0.8737
503 5H6 0.8736
504 KF5 0.8736
505 60L 0.8736
506 2HU 0.8735
507 JFJ 0.8735
508 TZP 0.8735
509 ANC 0.8735
510 GB5 0.8734
511 A7H 0.8734
512 FBF 0.8732
513 5WZ 0.8732
514 259 0.8731
515 8CC 0.8731
516 0K7 0.8730
517 GLU 0.8729
518 PRZ 0.8729
519 SQV 0.8727
520 TXW 0.8727
521 GOJ 0.8726
522 5OO 0.8726
523 NFM 0.8726
524 AVA 0.8724
525 4BF 0.8723
526 1WC 0.8723
527 3QV 0.8723
528 FC2 0.8722
529 657 0.8720
530 HWD 0.8720
531 AEH 0.8719
532 HNH 0.8719
533 9FH 0.8719
534 650 0.8718
535 A6W 0.8718
536 FBB 0.8714
537 ERZ 0.8713
538 R9J 0.8712
539 C9E 0.8712
540 5TY 0.8711
541 J38 0.8710
542 1ZC 0.8708
543 AEF 0.8708
544 LVD 0.8706
545 C2Y 0.8702
546 B85 0.8701
547 2LT 0.8700
548 PKU 0.8699
549 LTT 0.8698
550 6J9 0.8696
551 H7Y 0.8695
552 N8Y 0.8695
553 5RO 0.8695
554 TAG 0.8694
555 FQX 0.8694
556 D1G 0.8691
557 2LW 0.8690
558 SB7 0.8690
559 NK5 0.8689
560 0A1 0.8689
561 THU 0.8689
562 S2G 0.8687
563 D6G 0.8686
564 4FE 0.8686
565 BGP 0.8686
566 N4E 0.8686
567 R9G 0.8684
568 2HG 0.8684
569 DXK 0.8680
570 2LY 0.8678
571 1HN 0.8676
572 SHA 0.8674
573 P93 0.8673
574 2JM 0.8672
575 S0W 0.8672
576 GNM 0.8672
577 5WN 0.8670
578 3IL 0.8669
579 SSB 0.8669
580 L14 0.8669
581 NPA 0.8668
582 7OD 0.8667
583 C1M 0.8665
584 JBZ 0.8664
585 DRG 0.8663
586 HPS 0.8663
587 XRS 0.8663
588 F9Y 0.8662
589 DEZ 0.8661
590 DI6 0.8659
591 Q4G 0.8659
592 A51 0.8656
593 NIR 0.8656
594 MMS 0.8655
595 GLN 0.8653
596 AVX 0.8653
597 ZYV 0.8650
598 4MU 0.8647
599 JAW 0.8646
600 KW8 0.8645
601 N2Z 0.8645
602 NE2 0.8644
603 SAF 0.8644
604 VC3 0.8644
605 BP3 0.8644
606 FYR 0.8643
607 M4E 0.8643
608 IQQ 0.8642
609 6C5 0.8642
610 XFE 0.8641
611 2P3 0.8641
612 X6W 0.8640
613 Q06 0.8639
614 RP5 0.8637
615 F06 0.8636
616 GNY 0.8635
617 PRO GLY 0.8635
618 5DL 0.8635
619 AMH 0.8635
620 DZA 0.8634
621 BY5 0.8633
622 CS2 0.8631
623 H35 0.8630
624 L5D 0.8629
625 E4P 0.8629
626 F2W 0.8627
627 717 0.8626
628 LPK 0.8626
629 8HC 0.8623
630 YRL 0.8621
631 AH9 0.8621
632 DBS 0.8618
633 F6P 0.8614
634 V2Z 0.8613
635 ZYQ 0.8612
636 4R1 0.8606
637 MMJ 0.8606
638 S8V 0.8606
639 SSC 0.8605
640 6DP 0.8602
641 GWM 0.8601
642 ONH 0.8600
643 DHM 0.8600
644 MUX 0.8598
645 F40 0.8596
646 K2T 0.8595
647 NIY 0.8593
648 80G 0.8593
649 KLV 0.8588
650 2FQ 0.8588
651 SYV 0.8587
652 SEP 0.8584
653 WOE 0.8581
654 54X 0.8580
655 GLP 0.8574
656 ET2 0.8571
657 CIR 0.8571
658 BVS 0.8564
659 OW7 0.8564
660 API 0.8561
661 2JJ 0.8560
662 R52 0.8558
663 3XH 0.8557
664 NF3 0.8546
665 1QV 0.8545
666 RES 0.8540
667 7L4 0.8539
668 JTA 0.8539
669 M6P 0.8537
670 GGB 0.8520
671 49P 0.8518
672 MPP 0.8510
673 M4N 0.8506
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5C83; Ligand: 4YN; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 5c83.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback