-->
Receptor
PDB id Resolution Class Description Source Keywords
5C8W 1.8 Å EC: 2.7.11.12 PKG II'S AMINO TERMINAL CYCLIC NUCLEOTIDE BINDING DOMAIN (CN COMPLEX WITH CGMP HOMO SAPIENS BINDING SITES CYCLIC AMP CYCLIC GMP CYCLIC GMP-DEPENDENT KINASE TYPE II MUTAGENESIS SITE-DIRECTED PROTEIN BINDINGTRANSFERASE
Ref.: STRUCTURAL BASIS OF CYCLIC NUCLEOTIDE SELECTIVITY I CGMP-DEPENDENT PROTEIN KINASE II. J.BIOL.CHEM. V. 291 5623 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PCG C:302;
A:302;
E:302;
D:302;
F:302;
B:303;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
Kd = 43.8 nM
345.205 C10 H12 N5 O7 P c1nc2...
NA F:303;
C:303;
A:303;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
22.99 Na [Na+]
MLA D:301;
A:301;
B:302;
E:301;
F:301;
B:301;
C:301;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
submit data
104.061 C3 H4 O4 C(C(=...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5C8W 1.8 Å EC: 2.7.11.12 PKG II'S AMINO TERMINAL CYCLIC NUCLEOTIDE BINDING DOMAIN (CN COMPLEX WITH CGMP HOMO SAPIENS BINDING SITES CYCLIC AMP CYCLIC GMP CYCLIC GMP-DEPENDENT KINASE TYPE II MUTAGENESIS SITE-DIRECTED PROTEIN BINDINGTRANSFERASE
Ref.: STRUCTURAL BASIS OF CYCLIC NUCLEOTIDE SELECTIVITY I CGMP-DEPENDENT PROTEIN KINASE II. J.BIOL.CHEM. V. 291 5623 2016
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 5C6C Kd = 418 nM CMP C10 H12 N5 O6 P c1nc(c2c(n....
2 5C8W Kd = 43.8 nM PCG C10 H12 N5 O7 P c1nc2c(n1[....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 7 families.
1 5C6C Kd = 418 nM CMP C10 H12 N5 O6 P c1nc(c2c(n....
2 5C8W Kd = 43.8 nM PCG C10 H12 N5 O7 P c1nc2c(n1[....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 3OCP Kd = 27 nM CMP C10 H12 N5 O6 P c1nc(c2c(n....
2 5C6C Kd = 418 nM CMP C10 H12 N5 O6 P c1nc(c2c(n....
3 5C8W Kd = 43.8 nM PCG C10 H12 N5 O7 P c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: PCG; Similar ligands found: 57
No: Ligand ECFP6 Tc MDL keys Tc
1 35G 1 1
2 C2E 1 0.986111
3 PCG 1 1
4 4BW 0.806818 0.986111
5 1YD 0.806818 0.986111
6 5GP 5GP 0.743902 0.945205
7 4UR 0.731959 0.986111
8 6SW 0.627907 0.957747
9 1YC 0.616162 0.958333
10 6J7 0.58427 0.946667
11 CMP 0.534091 0.888889
12 2BA 0.534091 0.902778
13 GMP 0.53012 0.84
14 1SY 0.495575 0.986111
15 SGP 0.483871 0.835443
16 6SZ 0.483871 0.902778
17 3GP 0.478261 0.932432
18 1OR 0.474747 0.729412
19 G 0.468085 0.945946
20 5GP 0.468085 0.945946
21 7CH 0.467391 0.875
22 6SX 0.462366 0.847222
23 6JR 0.457944 0.930556
24 G2R 0.457143 0.897436
25 GPX 0.451923 0.906667
26 GP3 0.44898 0.934211
27 2GP 0.446809 0.92
28 GP2 0.444444 0.897436
29 GDP 0.444444 0.933333
30 GNH 0.44 0.921053
31 P2G 0.4375 0.893333
32 G2P 0.436893 0.897436
33 GMV 0.431373 0.909091
34 GTP 0.431373 0.933333
35 ALF 5GP 0.431373 0.851852
36 G1R 0.427184 0.921053
37 GCP 0.427184 0.909091
38 G3D 0.423077 0.945946
39 9GM 0.423077 0.909091
40 GSP 0.423077 0.886076
41 GNP 0.423077 0.909091
42 GDP AF3 0.420561 0.851852
43 G4P 0.415094 0.945946
44 GAV 0.415094 0.897436
45 P1G 0.414141 0.881579
46 Y9Z 0.410714 0.843373
47 GCP G 0.409091 0.906667
48 GDP ALF 0.407407 0.851852
49 ALF GDP 0.407407 0.851852
50 N6R 0.40708 0.818182
51 N6S 0.40708 0.818182
52 G G 0.40708 0.934211
53 G3A 0.403509 0.934211
54 YGP 0.401786 0.8875
55 GPG 0.4 0.922078
56 G5P 0.4 0.934211
57 0O2 0.4 0.945946
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5C8W; Ligand: PCG; Similar sites found with APoc: 335
This union binding pocket(no: 1) in the query (biounit: 5c8w.bio5) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 5H5O PCG None
2 5N87 N66 None
3 2YJ0 420 None
4 1VPM COA None
5 3HMO STU None
6 2CYE COA None
7 5E2N V14 None
8 5LXM ADP None
9 4WOP CTP None
10 3NWQ 2NC None
11 2QZT PLM None
12 2V1O COA None
13 3B8X G4M None
14 3LTW HLZ None
15 4WN5 MVC None
16 3M3E GAL A2G NPO None
17 5MT9 SRO None
18 2BS5 BGC GAL FUC None
19 3NOJ PYR None
20 2P3C 3TL None
21 3ZW2 NAG GAL FUC None
22 1QPR PPC None
23 4RT1 C2E None
24 5LLT DND None
25 4EWH T77 0.699301
26 3EKK GS2 1.3986
27 1IR3 ANP 1.3986
28 3BU5 ATP 1.3986
29 2P4Y C03 1.3986
30 4Q5M ROC 1.3986
31 6D61 4AA 1.3986
32 5JKG 6LF 2.0979
33 5EYK 5U5 2.0979
34 4C2V YJA 2.0979
35 3LA3 2FT 2.0979
36 3MTX PGT 2.0979
37 5HA0 LTD 2.0979
38 4C2W ANP 2.0979
39 4GAH 0ET 2.0979
40 1LQA NDP 2.0979
41 2RDE C2E 2.0979
42 2RGJ FAD 2.0979
43 1SWG BTN 2.34375
44 6CZ3 FLJ 2.7972
45 5H2U 1N1 2.7972
46 4CSV STI 2.7972
47 2B9J ADP 2.7972
48 3A76 SPD 2.7972
49 2B9H ADP 2.7972
50 4WW8 VD9 2.7972
51 3AQV TAK 2.7972
52 1RO7 CSF 2.7972
53 2WEI VGG 3.4965
54 5VCV 1N1 3.4965
55 1V0O INR 3.4965
56 5W4W 9WG 3.4965
57 4LOO SB4 3.4965
58 4TWP AXI 3.4965
59 4KBA 1QM 3.4965
60 2XHK AKG 3.4965
61 2VN9 GVD 3.4965
62 6A1G 9OL 3.4965
63 2XKO AKG 3.4965
64 2G37 FAD 3.4965
65 1RKD ADP 3.4965
66 1RKD RIB 3.4965
67 3VPH OXM 3.4965
68 3VPH NAD 3.4965
69 2HJR APR 3.4965
70 2ZW5 COA 3.4965
71 4H6Q FAD 3.4965
72 4H6Q TFB 3.4965
73 1SDW IYT 3.4965
74 2BL9 CP6 3.4965
75 6FCH PRP 3.4965
76 2VUT NAD 3.4965
77 2EQA AMP 3.4965
78 1TI7 NAP 3.4965
79 3PLS ANP 3.4965
80 5UR1 YY9 4.1958
81 5VC5 96M 4.1958
82 5TA6 79D 4.1958
83 4WW7 AMP 4.1958
84 5F6U 5VK 4.1958
85 4H4D 10E 4.1958
86 5X8I SQZ 4.1958
87 3AD8 FAD 4.1958
88 3AD8 PYC 4.1958
89 4Z1D PEP 4.1958
90 6GWR FEW 4.1958
91 5YIC 8VO 4.1958
92 1TFZ 869 4.1958
93 4WNP 3RJ 4.1958
94 6FYV 3NG 4.1958
95 2CWH PYC 4.1958
96 2CWH NDP 4.1958
97 2Q0L FAD 4.1958
98 4NZN 2OU 4.1958
99 4NZN ANP 4.1958
100 4FG8 ATP 4.1958
101 1EYQ NAR 4.1958
102 1PZG A3D 4.1958
103 4J5R A1R 4.1958
104 4YGF AZM 4.1958
105 4UXL 5P8 4.1958
106 4RD0 GDP 4.1958
107 4L80 OXL 4.1958
108 3SM2 478 4.54545
109 5G1X ADP 4.7619
110 3NW7 LGV 4.8951
111 5NKB 8ZT 4.8951
112 4YZC STU 4.8951
113 3E7O 35F 4.8951
114 4NFN 2KC 4.8951
115 2XK9 XK9 4.8951
116 4RFM 3P6 4.8951
117 4R5Z PMP 4.8951
118 4Y0X ADP 4.8951
119 3RG9 WRA 4.8951
120 3RG9 NDP 4.8951
121 4MOB COA 4.8951
122 4MZQ 1VU 4.8951
123 3FSM 2NC 4.8951
124 2YAB AMP 4.8951
125 2RIO ADP 4.8951
126 3KA2 2NC 4.8951
127 1RYO OXL 4.8951
128 3KJS DQ1 4.8951
129 2DKH 3HB 4.8951
130 5KF6 TFB 4.8951
131 5KF6 FAD 4.8951
132 5LVP ATP 4.8951
133 2V58 LZJ 4.8951
134 2IHT TPP 4.8951
135 3VPD ANP 4.8951
136 5M42 FMN 5.01792
137 3L9R L9R 5.10204
138 3WSJ MK1 5.17241
139 2Y6O 1N1 5.59441
140 3THR C2F 5.59441
141 3DAK ANP 5.59441
142 4FL3 ANP 5.59441
143 3SRV S19 5.59441
144 5DRB 5FJ 5.59441
145 1EBG PAH 5.59441
146 4BTK DTQ 5.59441
147 5HCY 60D 5.59441
148 2UUU FAD 5.59441
149 5Y72 DST 5.59441
150 2PO3 T4K 5.59441
151 1ELI PYC 5.59441
152 1VMK GUN 5.59441
153 2G50 PYR 5.59441
154 4CYI ATP 5.59441
155 4WNB 4BN 6.20155
156 4NW6 2NS 6.29371
157 1OPK P16 6.29371
158 5QIN J2V 6.29371
159 5JFS 6K0 6.29371
160 6GIN IR2 6.29371
161 1RM6 PCD 6.29371
162 2CIG 1DG 6.29371
163 5DQ8 FLF 6.29371
164 2Q7D ANP 6.29371
165 5YF9 NIO 6.29371
166 1GR0 NAD 6.29371
167 4FJU NAI 6.29371
168 1V8B NAD 6.29371
169 5T79 NDP 6.29371
170 6FCX FAD 6.29371
171 6ENO BJ8 6.29371
172 1V6A TRE 6.29371
173 4U0I 0LI 6.66667
174 4YEE 4CQ 6.66667
175 5TBM 79A 6.83761
176 4GJ3 0XP 6.99301
177 2YAK OSV 6.99301
178 3SXS PP2 6.99301
179 4G31 0WH 6.99301
180 5IH9 6BF 6.99301
181 5A6N U7E 6.99301
182 4ZAH T5K 6.99301
183 3GC8 B45 6.99301
184 3CY2 MB9 6.99301
185 3FW3 ETS 6.99301
186 3ZGJ RMN 6.99301
187 1M5B BN1 6.99301
188 5AX9 4KT 6.99301
189 4F2Q QUS 6.99301
190 2WQP WQP 6.99301
191 4EUU BX7 6.99301
192 2WSA MYA 7.69231
193 2WSA 646 7.69231
194 2JLD AG1 7.69231
195 4DC2 ADE 7.69231
196 3F7Z 34O 7.69231
197 3ZRM ZRM 7.69231
198 6F3G CJN 7.69231
199 4O8A FAD 7.69231
200 1TIW FAD 7.69231
201 1TIW TFB 7.69231
202 4QTB 38Z 7.69231
203 5IFK HPA 7.69231
204 5TO8 7FM 7.69231
205 2FNU PMP UD1 7.69231
206 1AFS NAP 7.69231
207 6G0X RAM GLC GLA NAG NDG NAG 7.69231
208 3C0G 3AM 7.69231
209 6FNU FAD 7.69231
210 6FKW PQQ 7.69231
211 1GUZ NAD 7.69231
212 1Z0N BCD 8.33333
213 3G5D 1N1 8.39161
214 1XJD STU 8.39161
215 5MJA 7O3 8.39161
216 3TTC ADP 8.39161
217 4USF 6UI 8.39161
218 3FPF MTA 8.39161
219 3FPF TNA 8.39161
220 3CKJ CIT 8.39161
221 4WO4 JLS 8.39161
222 5Y86 HRM 8.39161
223 1Y57 MPZ 8.39161
224 2YQS UD1 8.39161
225 4EUE NAI 8.39161
226 2HK5 1BM 9.09091
227 6BXI ANP 9.09091
228 2FB3 GTP 9.09091
229 4JNA FAD 9.09091
230 1D8C GLV 9.09091
231 4X1B MLI 9.09091
232 4N9I PCG 9.79021
233 4Y8D 49J 9.79021
234 5DEY 59T 9.79021
235 2V7O DRN 9.79021
236 5Y80 IRE 9.79021
237 3HQP OXL 9.79021
238 4PLT NAI 9.79021
239 4PLT OXM 9.79021
240 4YMJ 4EJ 9.79021
241 3VRY B43 10.4895
242 5FBN 5WF 10.4895
243 6GU6 1QK 10.4895
244 2GJ5 VD3 10.4895
245 4ZCW 4NG 10.4895
246 3FHR P4O 10.4895
247 2O1S TDP 10.4895
248 5HES 032 11.1888
249 1Q19 SSC 11.1888
250 4Z7X 3CX 11.1888
251 3KRL KRL 11.1888
252 5M06 ADP 11.1888
253 4O1P ANP 11.1888
254 1V97 MTE 11.1888
255 3MVH WFE 11.1888
256 4I2D APC 11.1888
257 2Y8L ADP 11.4943
258 2V92 ATP 11.4943
259 2V92 AMP 11.4943
260 1RE8 BD2 11.8881
261 1BZY IMU 11.8881
262 2YNE NHW 11.8881
263 2YNE YNE 11.8881
264 2A1L PCW 11.8881
265 5U3B 7TD 11.8881
266 2NX1 RP5 11.8881
267 2NX1 PEP 11.8881
268 4AG8 AXI 12.5874
269 3VHE 42Q 12.5874
270 4ASE AV9 12.5874
271 1Q8Y ADE 12.5874
272 4U44 3D9 12.5874
273 4CRL C1I 13.2867
274 5KOX RFP 13.2867
275 4IJP 1EH 13.2867
276 4X7Q 3YR 13.986
277 4XF6 ADP 13.986
278 4XF6 LIP 13.986
279 4XF6 INS 13.986
280 1FMB HYB 14.4231
281 5KEW 6SB 14.5833
282 2WLG SOP 14.6853
283 2XMY CDK 14.6853
284 2PVF ACP 14.6853
285 6ES0 BW8 14.6853
286 4BCM T7Z 14.6853
287 3HAZ FAD 14.6853
288 4XV1 904 15.3846
289 4CQE CQE 15.3846
290 2OFV 242 15.3846
291 4NMC FAD 15.3846
292 4NMC 2OP 15.3846
293 6GQM F8H 16.0839
294 3E8T UQ8 16.0839
295 2IGA XX2 16.0839
296 2IGA XX3 16.0839
297 2YC5 6BC 16.7832
298 5LXT ACP 16.7832
299 4LNU GDP 16.7832
300 2X2M X2M 18.1818
301 6ER9 FAD 18.1818
302 1U59 STU 18.1818
303 5ODT ADP 19.5652
304 3HZT J60 19.5804
305 3BJK CIT 20.2797
306 1D6S MET PLP 20.2797
307 3F5K CE5 20.2797
308 1IT7 GUN 20.979
309 3WBF API 22.3776
310 1Z2P I3S 23.0769
311 1Z2P ACP 23.0769
312 5YSQ INS 25.1748
313 4AVB CMP 25.8741
314 2E9L PLM 25.8741
315 2E9L OLA 25.8741
316 2E9L BGC 25.8741
317 1ZP9 ATP 28.6713
318 1ZTH ADP 28.6713
319 3RE4 TO1 29.3706
320 4YWV SSN 29.3706
321 3FYP PEP 29.3706
322 2PTM CMP 30.7692
323 3CF6 SP1 31.4685
324 3KCC CMP 31.4685
325 6CI9 NAP 32.8671
326 4NVP 7CH 33.5664
327 4MUV PCG 37.3239
328 3I59 N6S 39.8601
329 3I54 CMP 39.8601
330 3I59 N6R 39.8601
331 4CYD CMP 41.958
332 5KJZ PCG 43.3566
333 5K8S CMP 44.0559
334 3OF1 CMP 45.4545
335 1CX4 CMP 48.2517
Pocket No.: 2; Query (leader) PDB : 5C8W; Ligand: PCG; Similar sites found with APoc: 74
This union binding pocket(no: 2) in the query (biounit: 5c8w.bio3) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 3WV6 GAL GLC None
2 2P3B 3TL None
3 3E85 BSU 1.3986
4 4P5Z Q7M 2.0979
5 4OTH DRN 2.7972
6 1PN0 IPH 3.4965
7 2VZ6 FEF 3.4965
8 1KGQ NPI 3.4965
9 1KGQ SCO 3.4965
10 3LOO B4P 3.4965
11 1WD4 AHR 3.4965
12 4CLI 5P8 4.1958
13 3EEL 53T 4.1958
14 4K33 ACP 4.1958
15 1RRC ADP 4.1958
16 3TXO 07U 4.1958
17 5AHW CMP 4.1958
18 3H4L ANP 4.1958
19 4F4P 0SB 4.8951
20 4UX9 ANP 4.8951
21 4IZY 1J2 4.8951
22 3UIM ANP 4.8951
23 6ARJ SAH 4.8951
24 3V66 D3A 4.8951
25 5ML3 DL3 4.8951
26 3VMG 9CA 4.8951
27 5C03 AGS 4.8951
28 3AFN NAP 5.42636
29 2UUU PL3 5.59441
30 5XH2 NPO 5.59441
31 4JD3 PLM 5.59441
32 5WRI A3P 5.59441
33 5WRJ A3P 5.59441
34 4LIK CIT 6.29371
35 4XJ6 GH3 6.29371
36 4YEF 4CQ 6.74157
37 1PK8 ATP 6.99301
38 5KOR GDP 6.99301
39 1VJY 460 7.69231
40 4LAE 1VM 7.69231
41 4LAE NAP 7.69231
42 5F2T PLM 7.69231
43 2EXX NAP 7.69231
44 2J5V PCA 7.69231
45 1P9P SAH 7.69231
46 5A04 NDP 7.69231
47 5A04 BGC 7.69231
48 3MAG 3MA 7.69231
49 2H8H H8H 8.39161
50 4WHZ 3NL 8.39161
51 5ODQ 9SB 8.39161
52 2Y5D NAP 8.39161
53 5OCG 9R5 8.39161
54 6FK3 PPI 9.09091
55 1QY1 PRZ 9.09091
56 2GCG NDP 9.09091
57 4MZU COA 10.4895
58 3RGA LSB 11.1888
59 5ZTN CUR 11.8881
60 1MFI FHC 12.2807
61 2CM4 RCL 12.5874
62 1XVB BBX 12.5874
63 4CVZ TYR GLU LEU ASP GLU LYS PHE ASP ARG LEU 13.2867
64 4XBA 5GP 13.2867
65 5WX3 COA 13.2867
66 2VHJ ADP 15.3846
67 5EYP GDP 16.7832
68 3FV1 DYH 17.4825
69 3WBF NAP 22.3776
70 3B6C SDN 22.3776
71 4QIJ 1HA 23.7762
72 2B9I ADP 23.8095
73 4UAL 3FV 26.5734
74 1LDN NAD 27.972
Pocket No.: 3; Query (leader) PDB : 5C8W; Ligand: PCG; Similar sites found with APoc: 30
This union binding pocket(no: 3) in the query (biounit: 5c8w.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 5EH0 5NW None
2 4MKF AP5 None
3 1ZPT FAD 2.0979
4 4TWL ASC 2.0979
5 6G34 5ID 2.7972
6 3FGC FMN 3.4965
7 3FC2 IBI 4.1958
8 1VRP IOM 4.1958
9 5EOB 5QQ 4.8951
10 1U6R IOM 5.59441
11 4TVD BGC 6.29371
12 3CV6 HXS 6.29371
13 3IGO ANP 6.99301
14 1S3G AP5 6.99301
15 5K2M ADP 6.99301
16 5B48 TDN 6.99301
17 4DP3 MMV 7.69231
18 3VPC ADP 7.69231
19 5U98 1KX 7.69231
20 5ZCT ANP 8.39161
21 5CMK GLU 8.39161
22 1ZB6 DIN 9.09091
23 3PP0 03Q 9.79021
24 1AKY AP5 9.79021
25 5HQ0 LZ9 10.4895
26 3TKI S25 10.4895
27 2XVD AS6 11.1888
28 4XDA ADP 11.8881
29 4XDA RIB 11.8881
30 5GQX GLC GLC GLC GLC 16.0839
Pocket No.: 4; Query (leader) PDB : 5C8W; Ligand: PCG; Similar sites found with APoc: 35
This union binding pocket(no: 4) in the query (biounit: 5c8w.bio4) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 5JGA 6KC None
2 5Y4R C2E None
3 5T2Z 017 None
4 4YZN 4K5 2.0979
5 3KYG 5GP 5GP 2.0979
6 1A5Z NAD 2.7972
7 2Z7R STU 3.4965
8 5CDH TLA 4.1958
9 4GBD MCF 4.1958
10 3ETH ATP 4.1958
11 4M69 ANP 4.8951
12 3OVR 5SP 4.8951
13 3L9R L9Q 5.10204
14 5ESO TDP 5.59441
15 5ESO ISC 5.59441
16 5MY8 RXZ 6.29371
17 4BFM ANP 6.99301
18 4E1Z 0MX 6.99301
19 5UIU 8CG 7.69231
20 2C91 NAP 7.69231
21 1J3I NDP 8.39161
22 5ETJ IM5 8.39161
23 1KC7 PPR 9.09091
24 3DZD ADP 9.09091
25 2QE0 NAP 9.79021
26 3G08 FEE 10.101
27 2Y8L AMP 11.4943
28 3PVW QRX 12.5874
29 5ZZ6 NAD 12.5874
30 4WB7 ATP 12.5874
31 1T9D P22 13.986
32 2ICY UPG 14.6853
33 6MDE MEV 14.6853
34 3FC4 EDO 16.7832
35 5Y6Q MCN 18.1818
Pocket No.: 5; Query (leader) PDB : 5C8W; Ligand: PCG; Similar sites found with APoc: 7
This union binding pocket(no: 5) in the query (biounit: 5c8w.bio2) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 5NEA 8V8 None
2 1G8K MGD 4.8951
3 1WUU GLA 4.8951
4 3T4L ZEA 6.99301
5 6CQF F97 12.5874
6 3LXK MI1 13.2867
7 1U1I NAD 15.3846
Pocket No.: 6; Query (leader) PDB : 5C8W; Ligand: PCG; Similar sites found with APoc: 22
This union binding pocket(no: 6) in the query (biounit: 5c8w.bio6) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 1I7A PHE None
2 3NV3 GAL NAG MAN None
3 2XQQ SAC ARG GLY THR GLN THR GLU None
4 5DG2 GAL GLC None
5 4OB6 S2T 2.0979
6 5H4J FKM 2.0979
7 2DRC MTX 2.7972
8 2YMZ LAT 3.84615
9 1UU1 PMP HSA 4.1958
10 5JZJ AN2 4.8951
11 4PNI KQQ 4.8951
12 6CMJ F6J 5.59441
13 5OMY 9YE 5.59441
14 2QF7 AGS 5.59441
15 3ETG NDP 5.59441
16 3O9Z NAD 6.29371
17 3O9Z AKG 6.29371
18 1VBJ NAP 6.29371
19 5ZI2 NAD 6.99301
20 1ZB6 GST 9.09091
21 1QS8 IVA VAL VAL STA ALA STA 9.79021
22 4AU8 Z3R 20.2797
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