Receptor
PDB id Resolution Class Description Source Keywords
5CK5 2.4 Å NON-ENZYME: SIGNAL_HORMONE SIGNAL RECOGNITION PARTICLE RECEPTOR SRB-GDP-MG FROM CHAETOM THERMOPHILUM CHAETOMIUM THERMOPHILUM ARF-LIKE GTPASE PROTEIN TRANSLOCATION SIGNALING PROTEIN
Ref.: STRUCTURE AND SWITCH CYCLE OF SR BETA AS ANCESTRAL EUKARYOTIC GTPASE ASSOCIATED WITH SECRETORY MEMBRAN STRUCTURE V. 23 1838 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG A:402;
D:402;
B:402;
C:402;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
GDP D:401;
C:401;
B:401;
A:401;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5CK5 2.4 Å NON-ENZYME: SIGNAL_HORMONE SIGNAL RECOGNITION PARTICLE RECEPTOR SRB-GDP-MG FROM CHAETOM THERMOPHILUM CHAETOMIUM THERMOPHILUM ARF-LIKE GTPASE PROTEIN TRANSLOCATION SIGNALING PROTEIN
Ref.: STRUCTURE AND SWITCH CYCLE OF SR BETA AS ANCESTRAL EUKARYOTIC GTPASE ASSOCIATED WITH SECRETORY MEMBRAN STRUCTURE V. 23 1838 2015
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 263 families.
1 5CK4 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 5CK5 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 196 families.
1 5CK4 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 5CK5 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 171 families.
1 5CK4 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 5CK5 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5CK5; Ligand: GDP; Similar sites found: 494
This union binding pocket(no: 1) in the query (biounit: 5ck5.bio3) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4TMK T5A 0.002703 0.46359 None
2 3Q9L ATP 0.00008112 0.44477 1.15385
3 3ZQ6 ADP ALF 0.000008419 0.42525 1.26582
4 4E03 ADP 0.00002824 0.53094 1.45631
5 1OS1 PYR 0.00008121 0.53793 1.58228
6 1OS1 ATP 0.00007511 0.53793 1.58228
7 4KBF AMP 0.000396 0.46973 1.58228
8 2ZPT A3P 0.04642 0.41491 1.69492
9 2IYL GDP 0.0000001807 0.60882 1.76056
10 1IWE IMP 0.0002512 0.56534 1.89873
11 1G7C 5GP 0.000002009 0.5643 1.89873
12 2FSH ANP 0.0000909 0.50009 1.89873
13 4ZNL BEF ADP 0.00005314 0.48263 2.18978
14 3TK1 GDP 0.000000002046 0.73438 2.21519
15 5FG3 GDP 0.00000000286 0.71388 2.21519
16 4LC1 GDP 0.000000003472 0.68498 2.21519
17 1SKQ GDP 0.00000001542 0.67913 2.21519
18 2C77 GNP 0.00000006064 0.67741 2.21519
19 1DAR GDP 0.00000002955 0.64625 2.21519
20 1D2E GDP 0.00000005207 0.58662 2.21519
21 2C78 GNP 0.00000001589 0.55076 2.21519
22 1T5C ADP 0.000001225 0.51887 2.21519
23 3VMF GTP 0.0000000446 0.50381 2.21519
24 3EZ2 ADP 0.0001531 0.48933 2.21519
25 5IRN ADP 0.000009867 0.48819 2.21519
26 5HR5 ADP 0.00001614 0.46622 2.21519
27 3VM7 GLC 0.004277 0.43521 2.21519
28 3RC3 ANP 0.002614 0.43079 2.21519
29 3MGB PAP 0.005987 0.42917 2.21519
30 3DEF GDP 0.000001679 0.52217 2.29008
31 1VHT BA3 0.0001986 0.45635 2.29358
32 3A4M ADP 0.000002389 0.56037 2.30769
33 2ZFI ADP 0.000008598 0.53292 2.45902
34 1RYH GNP 0.00000000367 0.72263 2.46305
35 5KSZ GCP 0.000001683 0.54098 2.53165
36 2WKQ GTP 0.00000005069 0.52058 2.53165
37 2ZR9 DTP 0.00002151 0.51302 2.53165
38 2D7D ADP 0.00009508 0.50244 2.53165
39 2PL3 ADP 0.000082 0.50221 2.54237
40 1WF3 GNP 0.000000004717 0.51401 2.65781
41 3SBD GNP 0.00000009104 0.49542 2.6738
42 2OZE AGS 0.001725 0.48426 2.68456
43 1NN5 ANP 0.0048 0.47648 2.7907
44 1NN5 2DT 0.0048 0.47648 2.7907
45 5J1J ANP 0.000005837 0.45143 2.80702
46 2FJU GSP 0.00000003566 0.54832 2.80899
47 3E5H GNP 0.00000006337 0.50118 2.80899
48 3BER AMP 0.002183 0.42622 2.81124
49 1GHE ACO 0.01002 0.42302 2.82486
50 1MKY GDP 0.00000000125 0.70602 2.8481
51 2VVG ADP 0.0000001441 0.66241 2.8481
52 3P4X ADP 0.000008266 0.54953 2.8481
53 3IO3 ADP 0.001309 0.49068 2.8481
54 5MEX SZZ 0.03914 0.40688 2.8481
55 5MEX PAP 0.01939 0.40192 2.8481
56 4R98 GNH 0.0000005113 0.59057 2.95203
57 4QOS ADP 0.00005931 0.46926 3.01887
58 1YRB GDP 0.00000000006068 0.68963 3.05344
59 3WXM GTP 0.00000007201 0.6852 3.16456
60 4YC7 GNP 0.00000008111 0.67418 3.16456
61 3EC1 GDP 0.000000002768 0.66909 3.16456
62 3LRE ADP 0.000000178 0.65838 3.16456
63 1YQT ADP 0.000004338 0.58021 3.16456
64 5I0H ADP BEF 0.00001427 0.55957 3.16456
65 2WHX ADP 0.00001373 0.55468 3.16456
66 4R43 GDP 0.00004974 0.50119 3.16456
67 5FTB ANP 0.00006014 0.47037 3.16456
68 1IHU AF3 0.000003521 0.46601 3.16456
69 5M7P ADP 0.00001513 0.46275 3.16456
70 1IHU ADP 0.000003951 0.45571 3.16456
71 2JLR ANP 0.00006884 0.45444 3.16456
72 2FNA ADP 0.000006371 0.44995 3.16456
73 5FHD ADP ALF 0.0000218 0.44338 3.16456
74 4IOK XPO 0.01701 0.4376 3.16456
75 4IOK ADP 0.03209 0.42653 3.16456
76 4CNK FAD 0.0354 0.41112 3.16456
77 2J5V PCA 0.02032 0.41059 3.16456
78 3FYH ADP 0.00005592 0.40687 3.16456
79 3WY9 GDP 0.000000008183 0.6922 3.22581
80 3WYA GDP 0.000000007055 0.67368 3.22581
81 3VX3 ADP 0.000009206 0.47162 3.22581
82 3BFV ADP 0.000003294 0.55204 3.32103
83 4JLV ADP 0.00005714 0.50966 3.34572
84 2RCN GDP 0.00000000001442 0.79122 3.48101
85 1ZCB GDP 0.00000009738 0.67856 3.48101
86 5JCP GDP ALF 0.0000001502 0.55273 3.48101
87 4PFO ADP 0.00002997 0.55252 3.48101
88 1JWY GDP 0.0000003869 0.54821 3.48101
89 4HSE ADP 0.000006582 0.52265 3.48101
90 1JWY ADP 0.00001873 0.50313 3.48101
91 4IEE AGS 0.0001043 0.49724 3.48101
92 4LJ9 ACP 0.00006531 0.49505 3.48101
93 5N69 ADP 0.00001167 0.4852 3.48101
94 2VF7 ADP 0.00005967 0.48141 3.48101
95 4XGU ADP 0.00001721 0.48002 3.48101
96 5XDR ADP 0.0000765 0.47638 3.48101
97 1IN4 ADP 0.00001052 0.46529 3.48101
98 4ZG4 VO4 ADP 0.00001479 0.43116 3.48101
99 3FVQ ATP 0.00004966 0.43047 3.48101
100 2IMW DDS 0.01255 0.40539 3.48101
101 4D81 ADP 0.000003725 0.50738 3.53357
102 4FCW ADP 0.00001315 0.54695 3.53698
103 3PQC GDP 0.000000006585 0.63397 3.58974
104 3H86 AP5 0.0005533 0.50084 3.64583
105 2WIC GNP 0.00000004716 0.61625 3.74532
106 2GDJ ANP 0.0000902 0.48723 3.78788
107 4WZ6 ATP 0.00000225 0.5943 3.7931
108 1OXV ANP 0.000003438 0.56762 3.79747
109 2QEN ADP 0.00001807 0.54923 3.79747
110 2IS6 ADP 0.00001867 0.53627 3.79747
111 1WDT GTP 0.0000006 0.51336 3.79747
112 4YS0 ADP 0.00004673 0.45768 3.79747
113 1QHG ATP 0.003765 0.4331 3.79747
114 1X6V ADP 0.000005282 0.41864 3.79747
115 4OHY ANP 0.00007826 0.40203 3.79747
116 1FP6 ADP 0.00002142 0.47849 3.80623
117 2QZ4 ADP 0.000001389 0.53816 3.81679
118 4YDS ATP 0.00002574 0.53423 3.94737
119 3IUY AMP 0.003141 0.42972 3.94737
120 2ZE7 DST 0.000528 0.49117 3.95257
121 2ZE7 AMP 0.0004874 0.49117 3.95257
122 4P32 ADP 0.00002647 0.42934 4.01606
123 2B4D COA 0.0122 0.41374 4.09357
124 2AWN ADP 0.00000006277 0.69777 4.11392
125 5GJC ATP 0.00003154 0.50623 4.11392
126 5VGR GDP 0.00003237 0.4586 4.11392
127 2GK6 ADP 0.001338 0.45045 4.11392
128 3RLF ANP 0.00003001 0.42176 4.11392
129 4IDN GNP 0.00005752 0.42167 4.11392
130 1R0X ATP 0.0001053 0.49705 4.1958
131 5KSP GDP 0.0000007382 0.56885 4.21053
132 5EP2 AZU 0.00593 0.42938 4.29688
133 1TQ4 GDP 0.000000001288 0.5952 4.43038
134 4AG5 ADP 0.000002466 0.592 4.43038
135 3COB ADP 0.0000006991 0.54899 4.43038
136 4FRZ ADP 0.000002214 0.54644 4.43038
137 2Q2Y ADP 0.000127 0.54109 4.43038
138 2Q2Y MKR 0.0001474 0.53637 4.43038
139 2ZPA ADP 0.000007341 0.4683 4.43038
140 4A4Z ANP 0.0006244 0.44994 4.43038
141 1NY5 ADP 0.00006287 0.44916 4.43038
142 1OYY AGS 0.0008735 0.44462 4.43038
143 3CX8 GSP 0.00000007117 0.47368 4.4335
144 5G41 AP5 0.0001104 0.55039 4.4843
145 4KVX ACO 0.01424 0.41823 4.48718
146 3BOS CDP 0.00003148 0.5066 4.54545
147 4NON GDP 0.000000009564 0.50243 4.61538
148 5MZN ADP 0.0005608 0.4689 4.6729
149 5M04 GDP 0.00000000003104 0.80715 4.72222
150 4J0Q GDP 0.000000002844 0.71399 4.74684
151 4PPF FLC 0.000000514 0.6505 4.74684
152 5TSH ADP 0.000002078 0.59507 4.74684
153 5TSH ANP 0.000001313 0.56827 4.74684
154 4TMZ GSP 0.000000003823 0.55409 4.74684
155 4NCN GTP 0.000000004213 0.55344 4.74684
156 1R6B ADP 0.000001723 0.54933 4.74684
157 5LB3 ADP 0.00002192 0.52942 4.74684
158 1XKV ATP 0.00001632 0.49559 4.74684
159 1AZT GSP 0.00000008163 0.47388 4.74684
160 1Z2A GDP 0.000000000358 0.58008 4.7619
161 5X40 ACP 0.00003465 0.54506 4.79452
162 2PZE ATP 0.0000004794 0.63829 4.80349
163 2CHG ANP 0.00000592 0.49018 4.86726
164 1GRN GDP 0.00000007796 0.56243 4.92611
165 1JI0 ATP 0.000005392 0.56737 5
166 2OM2 GDP 0.0000001983 0.52808 5.06329
167 5KDO GDP 0.0000001945 0.52797 5.06329
168 1FQJ GDP 0.00000004256 0.52317 5.06329
169 1GOT GDP 0.0000002035 0.51508 5.06329
170 5I34 GDP 0.0000165 0.50929 5.06329
171 1FQK GDP 0.0000001709 0.50749 5.06329
172 1W0J ADP 0.00001882 0.4798 5.06329
173 2ODE ALF GDP 0.0000001027 0.47092 5.06329
174 1SVK ALF GDP 0.000000113 0.46157 5.06329
175 1W0J ADP BEF 0.000162 0.42717 5.06329
176 4PX9 ADP 0.00005001 0.51241 5.13699
177 1U0J ADP 0.0001276 0.49309 5.24345
178 5WDR GNP 0.000000001663 0.53259 5.26316
179 3R96 ACO 0.02241 0.41984 5.31915
180 3R96 AMP 0.02241 0.41984 5.31915
181 1G7S GDP 0.00000000521 0.65796 5.37975
182 4ITR GDP 0.00000002967 0.5613 5.37975
183 3DC4 ADP 0.000007298 0.56096 5.37975
184 3DZD ADP 0.00003238 0.47131 5.37975
185 1TAD GDP 0.00000008365 0.47099 5.37975
186 1TAD ALF 0.00000008365 0.47099 5.37975
187 2FAH GDP 0.00006525 0.46618 5.37975
188 3T34 GDP 0.00001625 0.44662 5.37975
189 1G6H ADP 0.0000003079 0.65668 5.44747
190 2BEK ATP 0.0002049 0.41031 5.44747
191 1F9V ADP 0.000002748 0.58862 5.4755
192 3T5G GDP 0.000000001975 0.65551 5.52486
193 4KFU ACP 0.0000004974 0.57293 5.66038
194 5K2M ADP 0.02583 0.40211 5.66038
195 1Z6T ADP 0.00002389 0.46066 5.6962
196 3ZS9 ADP ALF 0.00001359 0.42104 5.6962
197 2WOJ ADP ALF 0.00001266 0.42076 5.6962
198 1W5T ADP 0.0005682 0.41692 5.6962
199 1W5T ANP 0.0004208 0.40458 5.6962
200 2Z5F A3P 0.003885 0.43853 5.7047
201 4R2I ANP 0.0001917 0.49166 5.71429
202 3FWY ADP 0.000003834 0.58231 5.73248
203 2OFW ADX 0.000004509 0.61638 5.76923
204 1OFH ADP 0.008872 0.45612 5.80645
205 5BQ5 ADP BEF 0.000005544 0.51473 5.82011
206 5IFS ADP 0.000003714 0.57678 5.90717
207 2W58 ADP 0.00000009436 0.68395 5.94059
208 1L2T ATP 0.00004969 0.4077 5.95745
209 1Y63 ADP 0.0000007336 0.57974 5.97826
210 2ZEJ GDP 0.000000002232 0.52253 5.97826
211 2NGR GDP 0.00000001519 0.63717 5.98291
212 1KK1 GNP 0.000000008664 0.69102 6.01266
213 2XT3 ADP 0.0000006179 0.6268 6.01266
214 4RD0 GDP 0.000000006483 0.56117 6.01266
215 1V8K ANP 0.000008099 0.53341 6.01266
216 2DPY ADP 0.00004216 0.52377 6.01266
217 2XTN GTP 0.0000001226 0.5124 6.01266
218 4HI0 GDP 0.000000000721 0.60123 6.03015
219 1AQU A3P 0.006953 0.42211 6.06061
220 1CS4 GSP 0.00000007512 0.483 6.13208
221 2PEZ GGZ 0.000003027 0.40579 6.14525
222 2PEZ DAT 0.000003027 0.40579 6.14525
223 4U00 ADP 0.0000003087 0.53928 6.14754
224 1JJ7 ADP 0.000000401 0.64877 6.15385
225 4QRH 0O2 0.0006784 0.47622 6.19048
226 4LPS GDP 0.00000006048 0.61184 6.19835
227 2IXE ATP 0.00004331 0.42357 6.27306
228 4DCT GDP 0.000000001556 0.68 6.32911
229 2B8W ALF 5GP 0.00006768 0.53258 6.32911
230 4LYA ATP 0.0000138 0.51148 6.32911
231 1UKZ ADP 0.00006152 0.54909 6.40394
232 4TTQ ATP 0.000004982 0.56373 6.51163
233 4XTR ADP 0.000009137 0.47396 6.52174
234 4XTR ATP 0.00001293 0.44309 6.52174
235 4XVU ATP 0.00001409 0.44235 6.52174
236 5E5U MLI 0.01367 0.40079 6.53266
237 2Y65 ADP 0.00000238 0.52726 6.57534
238 2J0V GDP 0.000000007093 0.65088 6.60377
239 1T8U A3P 0.007582 0.42406 6.61765
240 4B47 GDP 0.000000000329 0.75847 6.64557
241 5GOE GDP 0.00000002902 0.60864 6.64557
242 3ZFD ANP 0.000009519 0.50169 6.64557
243 1YTM ATP 0.00002158 0.45313 6.64557
244 3H4S ADP 0.0000008241 0.6211 6.66667
245 2FAV APR 0.03185 0.40025 6.66667
246 3KJI ADP 0.0006388 0.50271 6.69291
247 4GOX A3P 0.0001146 0.41143 6.70927
248 2CJW GDP 0.00000000002644 0.77939 6.77083
249 5MVR ADP 0.000006016 0.53977 6.79012
250 1NJF ADP 0.000008715 0.56756 6.8
251 1NJF AGS 0.000012 0.5658 6.8
252 3CNL GNP 0.00000000195 0.72177 6.87023
253 2GJ8 ALF GDP 0.000000001824 0.52579 6.97674
254 4QM7 GTP 0.00001402 0.52227 7.01754
255 4D0N GDP 0.00000001199 0.68904 7.02703
256 3LXR GDP 0.00000001228 0.6221 7.02703
257 4YMU ATP 0.000004902 0.56031 7.08333
258 2CBZ ATP 0.0000008482 0.63085 7.173
259 2OBM ADP 0.0002388 0.4956 7.27848
260 4DKX GDP 0.0000000005841 0.7209 7.40741
261 2HT6 GDP 0.0000000001186 0.77951 7.47126
262 2QN6 GDP 0.000000003957 0.70718 7.52688
263 1HTW ADP 0.000000918 0.60267 7.59494
264 1BG2 ADP 0.0000006565 0.52875 7.59494
265 3RAB GNP 0.000000001407 0.77177 7.69231
266 1SVI GDP 0.000000001918 0.72211 7.69231
267 3A1S GDP 0.0000002259 0.5928 7.75194
268 4RZ3 ADP 0.00001029 0.48218 7.79661
269 3B7G ANP 0.00008705 0.47652 7.82609
270 5EOB 5QQ 0.02606 0.42815 7.83699
271 2XTZ GSP 0.0000000585 0.50294 7.91139
272 5LTJ ADP 0.00004723 0.48565 7.91139
273 5WRJ A3P 0.003432 0.44656 7.92079
274 3UIE ANP 0.000006808 0.50762 8
275 1ZJ6 G3D 0.0000000004733 0.69939 8.02139
276 2A9K GDP 0.0000000003664 0.64512 8.02139
277 4LHW GNP 0.0000000003795 0.55884 8.04598
278 3TNF GNP 0.0000000001984 0.54177 8.04598
279 1UAD GNP 0.000000002136 0.76259 8.08081
280 1LVG ADP 0.00000007204 0.65887 8.08081
281 5HPY GDP 0.00000008586 0.66339 8.10811
282 1CXZ GSP 0.0000002166 0.65288 8.13953
283 1H65 GDP 0.000002798 0.47783 8.14815
284 2A5J GDP 0.00000000009814 0.70604 8.37696
285 4CVN ADP 0.000003775 0.57493 8.37696
286 2D2F ADP 0.00004688 0.44368 8.4
287 4U5X GNP 0.00000001924 0.69883 8.42697
288 2X7I CIT 0.005164 0.40789 8.44156
289 5GVR LMR 0.00002901 0.5565 8.54701
290 4D0G GTP 0.000000000442 0.59418 8.57143
291 3B5J 12D 0.00001859 0.54113 8.64198
292 3RWO GDP 0.0000000007429 0.78581 8.64865
293 3DOE GTP 0.000000001123 0.5686 8.85417
294 4WOP CTP 0.0001726 0.42044 8.88889
295 2Y8E GNP 0.000000004802 0.53095 8.93855
296 4ZI2 GNP 0.0000000004396 0.59085 8.94737
297 4V03 ADP 0.000009549 0.50311 8.94942
298 2WJG GDP 0.000000008527 0.66897 9.04255
299 3NKV GNP 0.0000000002406 0.56218 9.14286
300 3EWA ANP 0.00002389 0.51179 9.17722
301 4H1V GNP 0.000003148 0.50583 9.17722
302 1JJV ATP 0.00001558 0.54934 9.2233
303 3KTA AP5 0.00004946 0.46011 9.24856
304 3W5J GDP 0.00000002185 0.70161 9.31373
305 2FFQ GSP 0.000000008436 0.51562 9.35672
306 1YZQ GNP 0.000000005739 0.51903 9.41177
307 3CPJ GDP 0.00000000002277 0.83457 9.41704
308 5KUT GDP 0.000000007899 0.70223 9.52381
309 1O3Y GTP 0.0000000004821 0.5781 9.63855
310 1J2J GTP 0.0000000004547 0.57774 9.63855
311 2J59 GTP 0.000000001189 0.56804 9.63855
312 2BME GNP 0.0000000004427 0.7972 9.67742
313 1KO8 6PG 0.000007548 0.47367 9.71429
314 1RE0 GDP 0.0000000001823 0.77065 9.7561
315 1S9D GDP 0.0000000002996 0.70826 9.7561
316 1GOJ ADP 0.00000009346 0.67396 9.81013
317 1KY3 GDP 0.0000000005757 0.76605 9.89011
318 3IIJ ADP 0.000002093 0.55977 10
319 4BAS GNP 0.0000001123 0.66712 10.0503
320 3T1O GDP 0.00000004231 0.60274 10.101
321 3T12 GDP ALF 0.00000007922 0.52827 10.101
322 4P3Y GDP 0.0000000009786 0.73599 10.1266
323 3U6B GDP 0.00000000104 0.73473 10.1266
324 1D8T GDP 0.000000001396 0.73374 10.1266
325 5JBQ GDP 0.000000001435 0.7029 10.1266
326 4G5G GDP 0.000000001705 0.69971 10.1266
327 3U6K GDP 0.000000004936 0.68013 10.1266
328 2BVN GNP 0.00000000342 0.6287 10.1266
329 4PC3 GDP 0.00000001283 0.60806 10.1266
330 1S8F GDP 0.000000002288 0.51804 10.1695
331 2HF9 GSP 0.00000001755 0.51716 10.177
332 2WJH GDP 0.00000001266 0.69236 10.241
333 2WJH FLC 0.0000004814 0.61985 10.241
334 1CJW COT 0.03299 0.40204 10.241
335 3BC1 GNP 0.0000000008556 0.78271 10.2564
336 1B7T ADP 0.00003526 0.48003 10.2564
337 1Z0A GDP 0.00000000008939 0.70721 10.3448
338 1SQ5 ADP 0.00002153 0.5008 10.3896
339 3NHB ADP 0.0000009215 0.61404 10.4575
340 1XX6 ADP 0.0001177 0.5085 10.4712
341 2KIN ADP 0.0000008871 0.52377 10.5042
342 2F9L GDP 0.000000001806 0.56698 10.5528
343 1Z0F GDP 0.00000000003753 0.74493 10.6145
344 2BCG GDP 0.00000000006542 0.65148 10.6796
345 3TKL GTP 0.0000000002065 0.57624 10.7143
346 1BO4 COA 0.00351 0.41421 10.7143
347 3TBK ANP 0.0001857 0.49233 10.7595
348 3Q72 GNP 0.000000000173 0.77173 10.8434
349 1NF3 GNP 0.0000001678 0.48678 10.9375
350 1A4R GNH 0.00000004064 0.57289 10.9948
351 1A4R GDP 0.00000003022 0.56274 10.9948
352 3SFV GDP 0.0000000001522 0.80663 11.0497
353 5IRR GSP 0.0000003225 0.49617 11.0759
354 5SZH GNP 0.0000000001555 0.8234 11.1111
355 1VG8 GNP 0.0000000004471 0.80006 11.1111
356 1VG0 GDP 0.0000000001685 0.67693 11.1111
357 1EK0 GNP 0.000000008209 0.51851 11.1765
358 5H67 ATP 0.001647 0.41917 11.25
359 5UWT GNP 0.00000000005363 0.84691 11.3924
360 5UWH GNP 0.00000000004791 0.56134 11.3924
361 5UWR GNP 0.00000000005588 0.56026 11.3924
362 5UWI GNP 0.00000000006175 0.55922 11.3924
363 5DHF GNP 0.00000000006192 0.55915 11.3924
364 5UWQ GNP 0.00000000006387 0.55913 11.3924
365 5UWJ GNP 0.00000000006554 0.55884 11.3924
366 5UWO GNP 0.00000000006524 0.55877 11.3924
367 5UWU GNP 0.00000000007954 0.55744 11.3924
368 5DIF GNP 0.00000000009034 0.55617 11.3924
369 5UWW GNP 0.00000000009188 0.55608 11.3924
370 5UWS GNP 0.00000000007022 0.54662 11.3924
371 5DI9 GNP 0.00000000008391 0.54525 11.3924
372 5UWP GNP 0.00000000009643 0.54427 11.3924
373 1KK8 BEF ADP 0.00002301 0.46408 11.5108
374 1OIV GDP 0.0000000004827 0.7953 11.5183
375 1OIX GDP 0.0000000005898 0.79089 11.5183
376 4GOJ GNP 0.0000000006878 0.58619 11.6667
377 4PJ3 ANP 0.0001181 0.45264 11.7089
378 5J1S ATP 0.00003419 0.4246 11.7155
379 1Z08 GNP 0.00000002339 0.53287 11.7647
380 3AB3 GDP 0.00000003359 0.69016 11.7886
381 5H56 TYD 0.00001187 0.58092 11.7949
382 5H56 ADP 0.00001187 0.58092 11.7949
383 1YZN GNP 0.0000000005304 0.54541 11.8919
384 2EW1 GNP 0.0000000008248 0.77711 11.9403
385 3AQ4 GDP 0.0000000001807 0.71663 11.9565
386 3GJ0 GDP 0.00000000003712 0.77261 12.2172
387 3GJ7 GDP 0.0000000000595 0.76386 12.2172
388 3GJ8 GDP 0.00000000003408 0.74566 12.2172
389 5JCZ GDP 0.0000000007855 0.61372 12.2905
390 3WYF GTP 0.00000000009205 0.54445 12.3288
391 4LX0 BEF GDP 0.000000002167 0.7652 12.4294
392 1VG1 GDP 0.00000000009647 0.79445 12.4324
393 1VG9 GDP 0.0000000002121 0.71681 12.4324
394 2W2X GSP 0.00000001959 0.55665 12.4324
395 4HAT GNP 0.00000000009314 0.83783 12.5
396 3GJX GTP 0.00000000009804 0.83358 12.5
397 1IBR GNP 0.00000000007866 0.55735 12.5
398 4YLG GDP 0.0000000002185 0.64861 12.7168
399 2HV8 GTP 0.0000000008254 0.55211 12.7907
400 1TU3 GNP 0.0000000003889 0.80006 12.8655
401 1Z0J GTP 0.000000001568 0.5345 12.9412
402 1R2Q GNP 0.000000005036 0.46438 12.9412
403 2V7Q ATP 0.00001086 0.50019 13.0137
404 2V7Q ADP 0.0001089 0.48375 13.0137
405 2CK3 ANP 0.0002006 0.42485 13.0137
406 2CK3 ADP 0.0001914 0.40267 13.0137
407 1YVD GNP 0.0000000009707 0.54956 13.0178
408 4KVG GTP 0.0000000002464 0.56289 13.0952
409 2D7C GTP 0.0000000009327 0.78081 13.1737
410 4HDQ GNP 0.000000001458 0.77395 13.1737
411 4HDO GNP 0.0000000006899 0.5407 13.1737
412 1GUA GNP 0.0000000008773 0.53867 13.1737
413 3X1Z GNP 0.000000000993 0.52724 13.1737
414 3QBT GNP 0.00000000036 0.55967 13.5714
415 2XAU ADP 0.00009467 0.4611 13.6076
416 4Q9N 0WE 0.0134 0.40399 13.7584
417 2EFE GNH 0.0000000007472 0.65502 13.8122
418 2GCN GDP 0.00000007936 0.67465 13.9303
419 2GCO GNP 0.00000006212 0.6703 13.9303
420 4C4P GNP 0.000000000537 0.54527 14.0187
421 4MKF AP5 0.0001043 0.5469 14.2857
422 5K5Z ANP 0.0001032 0.40876 14.3312
423 1KSH GDP 0.000000001427 0.75833 14.5161
424 3GJ5 GDP 0.00000000005479 0.7379 14.7059
425 1QHH ATP 0.004868 0.40414 14.7929
426 3WYG GTP 0.0000000002342 0.53753 14.8352
427 1OW3 GDP 0.00000008192 0.66439 15.0259
428 3GJ3 GDP 0.00000000008767 0.75636 15.1515
429 1WA5 GTP 0.0000000001954 0.50884 15.3409
430 1GP2 GDP 0.0000002945 0.50383 15.493
431 5IRC GDP 0.00000036 0.62597 15.5914
432 1KMQ GNP 0.0000001848 0.65914 15.7609
433 3ZIA ADP 0.000011 0.55693 15.873
434 3ZIA ATP 0.00001053 0.55159 15.873
435 1Z0K GTP 0.0000000003151 0.58509 15.942
436 3REF GDP 0.00000004616 0.53181 15.9794
437 4XOI GTP 0.0000002962 0.49028 16.1111
438 4XSH GSP 0.00000009485 0.54629 16.2011
439 3DKP ADP 0.00003187 0.52516 16.3265
440 1TX4 ALF GDP 0.0000002903 0.50065 16.3842
441 5HCN GCP 0.0000000003388 0.70769 16.4751
442 4M9Q GNP 0.000000002817 0.57059 17.1806
443 5BXQ GDP 0.00000000003246 0.81726 17.3228
444 1OE0 TTP 0.002318 0.45847 17.3913
445 5UQW GDP 0.0000000001803 0.57723 17.4603
446 3MJH GTP 0.000000001388 0.54442 17.6471
447 2G77 GDP 0.0000000003172 0.64684 17.6768
448 2G77 AF3 0.01202 0.40829 17.6768
449 2C5L GTP 0.000000000344 0.54771 17.9191
450 3QF7 ANP 0.00002298 0.45013 18.0822
451 1ZD9 GDP 0.00000000008222 0.6455 18.0851
452 1UPT GTP 0.000000001267 0.57705 18.1287
453 1M2O GNP 0.000000003364 0.53444 18.3544
454 5E95 GDP 0.000000000184 0.65385 18.4524
455 1NVU GTP 0.000000000865 0.78548 18.6747
456 3KUD GDP 0.0000000004093 0.60983 18.6747
457 1WQ1 GDP 0.0000000003438 0.58197 18.6747
458 2UZI GTP 0.0000000007901 0.55142 18.6747
459 3DDC GNP 0.0000000005602 0.54134 18.6747
460 1NVV GNP 0.0000000005747 0.54105 18.6747
461 1CLU DBG 0.000000002936 0.42748 18.6747
462 1WQ1 AF3 0.00883 0.41922 18.6747
463 1F6B GDP 0.0000000002733 0.77266 18.6869
464 2HCJ GDP 0.000000001288 0.73032 18.9189
465 1D5C GDP 0.0000000004644 0.64115 19.1358
466 2QTV GNP 0.000000000137 0.57838 19.1617
467 4DSU GDP 0.0000000008466 0.53961 19.5767
468 5TB5 GDP 0.0000000001072 0.70319 20
469 5TAR GDP 0.0000000001012 0.68221 20
470 2X77 GDP 0.00000000005704 0.73776 20.1058
471 4V0K GDP 0.000000007927 0.53309 20.1183
472 2VB6 ADP BEF 0.00002337 0.4269 20.1342
473 4BQS ADP 0.000009061 0.53287 20.4545
474 5O2T GSP 0.0000000003653 0.54686 20.7101
475 5DI3 GNP 0.000000002983 0.57096 21.0811
476 5UFQ GNP 0.0000000004508 0.55655 21.0843
477 1Z06 GNP 0.0000000001357 0.57833 21.164
478 5XCO GDP 0.00000000006304 0.81297 21.6374
479 4ZKD GDP 0.00000001492 0.50736 21.8354
480 3Q85 GNP 0.00000000008265 0.79249 21.8935
481 1M7G ADX 0.000003184 0.61228 22.2749
482 1M7G AV2 0.0000003943 0.61228 22.2749
483 1M7G ADP 0.00000407 0.60286 22.2749
484 1LFD GNP 0.0000000008549 0.54912 24.1379
485 3GJ4 GDP 0.00000000004067 0.77093 24.2424
486 4DID GDP 0.00000001252 0.64049 27.6316
487 5EE5 GTP 0.00000000008015 0.61396 31.5789
488 2A5F GTP 0.000000004439 0.5412 32
489 1R4A GNP 0.0000000002021 0.57517 32.1212
490 4KAX GTP 0.000000001766 0.57687 32.5444
491 3PCR GTP 0.000000001359 0.56551 33.3333
492 1YZG GDP 0.0000000007104 0.6922 33.5196
493 2W83 GTP 0.000000001477 0.56629 33.9394
494 3N5C GDP 0.0000000006001 0.72031 34.5679
Pocket No.: 2; Query (leader) PDB : 5CK5; Ligand: GDP; Similar sites found: 17
This union binding pocket(no: 2) in the query (biounit: 5ck5.bio1) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5CUQ NSC 0.03052 0.40851 1.87266
2 2PT9 2MH 0.04703 0.40062 2.21519
3 3R7F CP 0.01684 0.40017 2.30263
4 1S7G NAD 0.03832 0.40217 3.16206
5 2O0J ADP 0.007988 0.40079 3.48101
6 5JCM ISD 0.03984 0.42713 4.43038
7 5JCM NAD 0.03811 0.42713 4.43038
8 5JCM FAD 0.03811 0.42713 4.43038
9 1WRA PC 0.02606 0.40351 4.43038
10 1NST A3P 0.0006851 0.41302 5.06329
11 1D2N ANP 0.0008422 0.40054 5.14706
12 4HIA FMN 0.04359 0.40239 7.38636
13 3BD9 A3P 0.00531 0.404 7.85714
14 5LTJ BEF 0.001184 0.47067 7.91139
15 2PX8 SAH 0.02111 0.40182 8.17844
16 4TQK NAG 0.01305 0.4038 8.5443
17 4L2I FAD 0.03437 0.40892 9.17722
Pocket No.: 3; Query (leader) PDB : 5CK5; Ligand: GDP; Similar sites found: 2
This union binding pocket(no: 3) in the query (biounit: 5ck5.bio2) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3VP6 HLD 0.02519 0.40411 6.96203
2 4L2I NAD 0.03648 0.41555 9.17722
Pocket No.: 4; Query (leader) PDB : 5CK5; Ligand: GDP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 5ck5.bio4) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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