-->
Receptor
PDB id Resolution Class Description Source Keywords
5CKW 2.49 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF LEGK4_AMPPNP KINASE LEGIONELLA PNEUMOPHILA (STRAIN LENS) LEGIONELLA BACTERIAL EFFECTORS SERINE/THREONINE KINASE TYSECRETION SYSTEM TRANSFERASE
Ref.: THE STRUCTURE OF LEGIONELLA PNEUMOPHILA LEGK4 TYPE SECRETION SYSTEM (T4SS) EFFECTOR REVEALS A NOVEL DI EUKARYOTIC-LIKE KINASE. SCI REP V. 5 14602 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CA A:504;
B:504;
Part of Protein;
Invalid;
none;
none;
submit data
40.078 Ca [Ca+2...
MG A:502;
B:502;
B:503;
A:503;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
ANP A:501;
B:501;
Valid;
Valid;
none;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5CKW 2.49 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF LEGK4_AMPPNP KINASE LEGIONELLA PNEUMOPHILA (STRAIN LENS) LEGIONELLA BACTERIAL EFFECTORS SERINE/THREONINE KINASE TYSECRETION SYSTEM TRANSFERASE
Ref.: THE STRUCTURE OF LEGIONELLA PNEUMOPHILA LEGK4 TYPE SECRETION SYSTEM (T4SS) EFFECTOR REVEALS A NOVEL DI EUKARYOTIC-LIKE KINASE. SCI REP V. 5 14602 2015
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 5CKW - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 5CKW - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 5CKW - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 373
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 AP5 0.802632 0.945205
5 ADP 0.802632 0.972222
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 HEJ 0.772152 0.972222
9 ATP 0.772152 0.972222
10 AT4 0.769231 0.933333
11 AN2 0.769231 0.986111
12 5FA 0.7625 0.972222
13 AQP 0.7625 0.972222
14 M33 0.759494 0.932432
15 MAP 0.752941 0.972973
16 ACP 0.75 0.945946
17 AR6 0.740741 0.945205
18 APR 0.740741 0.945205
19 ACQ 0.73494 0.945946
20 AD9 0.731707 0.945946
21 SAP 0.731707 0.921053
22 AGS 0.731707 0.921053
23 A 0.723684 0.944444
24 AMP 0.723684 0.944444
25 ATF 0.717647 0.933333
26 ADX 0.716049 0.851852
27 CA0 0.716049 0.92
28 6YZ 0.709302 0.945946
29 50T 0.707317 0.932432
30 PRX 0.698795 0.87013
31 ABM 0.696203 0.893333
32 AP2 0.679012 0.933333
33 A12 0.679012 0.933333
34 APC 0.678571 0.933333
35 T99 0.674419 0.933333
36 TAT 0.674419 0.933333
37 A22 0.674157 0.958904
38 SRA 0.670886 0.894737
39 SRP 0.670455 0.883117
40 5AL 0.666667 0.906667
41 A1R 0.659341 0.884615
42 ADQ 0.659341 0.92
43 A3R 0.659341 0.884615
44 3OD 0.648936 0.92
45 BIS 0.648936 0.909091
46 5SV 0.648352 0.82716
47 9X8 0.645161 0.896104
48 OAD 0.645161 0.92
49 25L 0.642105 0.958904
50 AMO 0.641304 0.907895
51 G5P 0.636364 0.897436
52 DLL 0.634409 0.906667
53 AHX 0.634409 0.897436
54 00A 0.634409 0.860759
55 ADV 0.632184 0.907895
56 RBY 0.632184 0.907895
57 ADP PO3 0.632184 0.917808
58 NB8 0.631579 0.897436
59 25A 0.630435 0.945205
60 OOB 0.630435 0.906667
61 8QN 0.630435 0.906667
62 G3A 0.626263 0.897436
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 TXA 0.614583 0.907895
67 1ZZ 0.614583 0.819277
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 9ZD 0.612903 0.909091
71 9ZA 0.612903 0.909091
72 3UK 0.610526 0.894737
73 SON 0.604651 0.907895
74 ADP ALF 0.604396 0.848101
75 ALF ADP 0.604396 0.848101
76 PR8 0.604167 0.829268
77 B5V 0.604167 0.883117
78 WAQ 0.604167 0.860759
79 4UV 0.6 0.871795
80 GAP 0.6 0.87013
81 PTJ 0.597938 0.873418
82 FYA 0.597938 0.881579
83 VO4 ADP 0.597826 0.906667
84 ADP VO4 0.597826 0.906667
85 LMS 0.597561 0.829268
86 UP5 0.596154 0.896104
87 FA5 0.59596 0.883117
88 YAP 0.59596 0.871795
89 PAP 0.595506 0.958333
90 A4P 0.59434 0.823529
91 XAH 0.59 0.841463
92 4UU 0.588235 0.871795
93 AFH 0.588235 0.8625
94 9SN 0.585859 0.85
95 2A5 0.58427 0.894737
96 T5A 0.583333 0.821429
97 DQV 0.582524 0.932432
98 NAI 0.580952 0.884615
99 B5M 0.58 0.871795
100 B5Y 0.58 0.871795
101 ITT 0.579545 0.917808
102 ATR 0.577778 0.944444
103 OMR 0.575472 0.831325
104 5AS 0.574713 0.781609
105 YLP 0.571429 0.8
106 48N 0.571429 0.873418
107 AP0 0.570093 0.873418
108 4TC 0.570093 0.873418
109 7D3 0.569767 0.881579
110 ADJ 0.568807 0.831325
111 GNP 0.568421 0.922078
112 9GM 0.568421 0.922078
113 DAL AMP 0.568421 0.881579
114 6V0 0.566038 0.873418
115 TXD 0.566038 0.884615
116 DND 0.566038 0.907895
117 NAX 0.566038 0.851852
118 4UW 0.566038 0.839506
119 NXX 0.566038 0.907895
120 XYA 0.565789 0.821918
121 RAB 0.565789 0.821918
122 ADN 0.565789 0.821918
123 AOC 0.564706 0.8
124 7D4 0.561798 0.881579
125 ADP BMA 0.561224 0.894737
126 TXE 0.560748 0.884615
127 TYM 0.560748 0.883117
128 GA7 0.557692 0.883117
129 YLC 0.555556 0.819277
130 YLB 0.555556 0.8
131 139 0.554545 0.851852
132 5N5 0.551282 0.797297
133 JB6 0.55 0.860759
134 LAQ 0.54717 0.819277
135 F2R 0.544643 0.843373
136 MYR AMP 0.544554 0.797619
137 5CD 0.544304 0.783784
138 A4D 0.544304 0.797297
139 80F 0.54386 0.821429
140 7MD 0.542857 0.864198
141 6AD 0.542553 0.886076
142 A2R 0.541667 0.958904
143 UPA 0.541284 0.884615
144 YLA 0.540541 0.8
145 A A 0.54 0.918919
146 BTX 0.539823 0.821429
147 COD 0.539823 0.793103
148 HFD 0.537634 0.921053
149 G5A 0.537634 0.781609
150 3DH 0.535714 0.753247
151 AYB 0.535714 0.790698
152 CNA 0.535714 0.907895
153 BT5 0.535088 0.811765
154 ATP A A A 0.533981 0.905405
155 IOT 0.531532 0.811765
156 MTA 0.53012 0.753247
157 3AM 0.529412 0.90411
158 A3P 0.52809 0.944444
159 PPS 0.526316 0.851852
160 NAD 0.526316 0.906667
161 EP4 0.52439 0.734177
162 7D5 0.52381 0.855263
163 AMP DBH 0.52381 0.87013
164 J7C 0.522727 0.75
165 A5A 0.520833 0.809524
166 EAD 0.520661 0.851852
167 TSB 0.520408 0.821429
168 AHZ 0.518519 0.797619
169 DTA 0.518072 0.766234
170 M2T 0.518072 0.716049
171 A3D 0.517241 0.894737
172 6RE 0.517241 0.740741
173 YLY 0.516949 0.790698
174 SSA 0.515464 0.802326
175 NA7 0.514852 0.933333
176 ARG AMP 0.514019 0.809524
177 AR6 AR6 0.514019 0.893333
178 7MC 0.513514 0.843373
179 A2P 0.511111 0.930556
180 52H 0.510204 0.781609
181 VMS 0.510204 0.790698
182 54H 0.510204 0.790698
183 TYR AMP 0.509434 0.848101
184 TAD 0.509259 0.8625
185 NAQ 0.508333 0.85
186 A3N 0.505618 0.766234
187 AV2 0.505155 0.893333
188 53H 0.50505 0.781609
189 5CA 0.50505 0.802326
190 8X1 0.50505 0.755556
191 ARU 0.504951 0.839506
192 ZID 0.504132 0.894737
193 P1H 0.504 0.831325
194 NAE 0.5 0.871795
195 3AT 0.5 0.945205
196 AVV 0.5 0.873418
197 P5A 0.495146 0.747253
198 NSS 0.49505 0.802326
199 LSS 0.49505 0.764045
200 DSZ 0.49505 0.802326
201 N0B 0.491803 0.8
202 AF3 ADP 3PG 0.491071 0.817073
203 NVA LMS 0.490196 0.755556
204 DAT 0.489362 0.881579
205 IMO 0.488889 0.90411
206 ZAS 0.488636 0.792208
207 FDA 0.488372 0.813953
208 NAJ PZO 0.487395 0.85
209 4TA 0.487179 0.788235
210 LPA AMP 0.486486 0.797619
211 LEU LMS 0.485437 0.755556
212 DTP 0.484536 0.881579
213 V3L 0.484536 0.945205
214 S4M 0.483516 0.651685
215 GJV 0.483516 0.731707
216 DZD 0.483051 0.8625
217 2AM 0.482759 0.917808
218 5AD 0.481013 0.726027
219 GSU 0.480769 0.781609
220 KAA 0.480769 0.755556
221 NDE 0.480315 0.907895
222 M24 0.479339 0.851852
223 MAO 0.478261 0.761905
224 NEC 0.477778 0.727273
225 DSH 0.477778 0.707317
226 FAS 0.477273 0.831325
227 FAD 0.477273 0.831325
228 RGT 0.476636 0.933333
229 9K8 0.47619 0.698925
230 G A A A 0.474576 0.85
231 0WD 0.474576 0.897436
232 FNK 0.474074 0.786517
233 5X8 0.473684 0.74359
234 6FA 0.473282 0.821429
235 NDC 0.472868 0.85
236 FB0 0.472868 0.786517
237 YSA 0.472222 0.781609
238 7DD 0.468085 0.958333
239 OVE 0.466667 0.881579
240 MHZ 0.463158 0.701149
241 8PZ 0.462963 0.802326
242 A G 0.462185 0.860759
243 AMP NAD 0.462185 0.881579
244 A3G 0.461538 0.779221
245 NAJ PYZ 0.459677 0.809524
246 6C6 0.459184 0.858974
247 SFG 0.458333 0.730769
248 U A G G 0.458333 0.860759
249 7D7 0.45679 0.723684
250 128 0.45614 0.8
251 SFD 0.455224 0.736842
252 6IA 0.454545 0.817073
253 DDS 0.454545 0.855263
254 GDP 0.454545 0.896104
255 ODP 0.453782 0.886076
256 NJP 0.453782 0.921053
257 7DT 0.453608 0.958333
258 A7D 0.452632 0.75641
259 Z5A 0.452381 0.802326
260 WSA 0.452174 0.790698
261 U A 0.45082 0.884615
262 7C5 0.45045 0.797468
263 FAY 0.449275 0.841463
264 NDP 0.449153 0.897436
265 SA8 0.44898 0.690476
266 A5D 0.44898 0.766234
267 71V 0.446809 0.884615
268 GGZ 0.446602 0.804878
269 RFL 0.446043 0.802326
270 2SA 0.445545 0.907895
271 SAI 0.444444 0.716049
272 GP3 0.444444 0.897436
273 SAH 0.444444 0.725
274 PO4 PO4 A A A A PO4 0.443396 0.878378
275 A A A 0.443396 0.881579
276 4YB 0.442478 0.764045
277 SMM 0.441176 0.670455
278 S7M 0.441176 0.674419
279 GTP 0.441176 0.896104
280 Y3J 0.440476 0.706667
281 SAM 0.44 0.674419
282 649 0.439655 0.747253
283 12D 0.438596 0.809524
284 A3S 0.4375 0.789474
285 NPW 0.436975 0.864198
286 GCP 0.436893 0.873418
287 AAT 0.435644 0.690476
288 GNH 0.435644 0.909091
289 EEM 0.435644 0.674419
290 ETB 0.435484 0.813953
291 DCA 0.435484 0.804598
292 N6P 0.433962 0.890411
293 NZQ 0.433333 0.886076
294 TXP 0.433333 0.897436
295 PGS 0.43299 0.860759
296 APU 0.432203 0.871795
297 PUA 0.432 0.8625
298 62F 0.431655 0.841463
299 F2N 0.431507 0.795455
300 DA 0.430108 0.855263
301 D5M 0.430108 0.855263
302 J7V 0.429688 0.813953
303 NIA 0.428571 0.848101
304 COA 0.428571 0.804598
305 6K6 0.428571 0.905405
306 A3T 0.428571 0.8
307 0T1 0.428571 0.804598
308 P5F 0.427586 0.804598
309 AAM 0.425532 0.944444
310 0UM 0.424528 0.682353
311 8Q2 0.423729 0.775281
312 G1R 0.423077 0.884615
313 AMZ 0.422222 0.891892
314 C2R 0.422222 0.88
315 A U 0.420168 0.848101
316 IDP 0.42 0.894737
317 GSP 0.419048 0.851852
318 30N 0.418605 0.736842
319 CAO 0.418605 0.777778
320 DG1 0.418605 0.897436
321 1DG 0.418605 0.897436
322 COS 0.418605 0.786517
323 AMX 0.418605 0.813953
324 TM1 0.418182 0.797619
325 A6D 0.416667 0.746988
326 K15 0.416667 0.666667
327 V1N 0.415929 0.893333
328 CMX 0.415385 0.804598
329 SCO 0.415385 0.804598
330 GEK 0.415094 0.719512
331 XNP 0.414634 0.851852
332 NHD 0.414634 0.881579
333 9JJ 0.413793 0.841463
334 AIR 0.413793 0.876712
335 COK 0.413534 0.786517
336 G2R 0.412844 0.8625
337 ACO 0.412214 0.777778
338 FAM 0.412214 0.786517
339 FCX 0.412214 0.777778
340 NAP 0.410853 0.92
341 FA9 0.409396 0.843373
342 SXZ 0.409091 0.694118
343 HAX 0.409091 0.806818
344 TAP 0.407692 0.884615
345 2MC 0.407407 0.752688
346 62X 0.407407 0.651685
347 GKE 0.40708 0.8625
348 GDC 0.40708 0.8625
349 GDD 0.40708 0.8625
350 3KK 0.406015 0.786517
351 FYN 0.406015 0.804598
352 NVA 2AD 0.405941 0.740741
353 NA0 0.40458 0.907895
354 101 0.404255 0.855263
355 G 0.40404 0.883117
356 5GP 0.40404 0.883117
357 HDV 0.403846 0.87013
358 MGP 0.403846 0.8625
359 OXK 0.402985 0.786517
360 MCD 0.402985 0.786517
361 CA6 0.402985 0.714286
362 SOP 0.402985 0.786517
363 3AD 0.402299 0.783784
364 S8M 0.401869 0.78481
365 YE1 0.40146 0.795455
366 NMX 0.4 0.782609
367 7RP 0.4 0.902778
368 2VA 0.4 0.779221
369 1VU 0.4 0.777778
370 CO6 0.4 0.786517
371 CMC 0.4 0.786517
372 6G0 0.4 0.8625
373 GMV 0.4 0.873418
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5CKW; Ligand: ANP; Similar sites found with APoc: 449
This union binding pocket(no: 1) in the query (biounit: 5ckw.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 2IO8 ADP 1.33038
2 3V4S ADP 1.55039
3 3V4S ATP 1.55039
4 4WTV ATP 1.55211
5 1GSA ADP 1.58228
6 1GPE FAD 1.77384
7 1EHI ADP 1.85676
8 1UUO ORO 1.88172
9 1UUO BRF 1.88172
10 1UUO FMN 1.88172
11 5GZ9 ANP 1.96721
12 6C1S EFV 1.99557
13 2PUL ACP 2.01511
14 1IA9 ANP 2.14286
15 5AE9 OKO 2.21729
16 6EZ6 C5Z 2.21729
17 3K5I AIR 2.23325
18 3K5I ADP 2.23325
19 4GYI ADP 2.267
20 2EV9 SKM 2.28137
21 2Q7D ANP 2.31214
22 2YNE YNE 2.34375
23 2YNE NHW 2.34375
24 2CIR BG6 2.3569
25 2PYW ADP 2.38095
26 3THR C2F 2.38908
27 3KAL ADP 2.43902
28 4MV1 ADP 2.43902
29 3VPD ANP 2.4911
30 2E5A LAQ 2.59366
31 1E4E ADP 2.62391
32 4OCJ NDG 2.63852
33 4YNU LGC 2.66075
34 4ZGP ADP 2.73038
35 4CYI ATP 2.73973
36 2IF8 ADP 2.75482
37 2R7K ACP 2.77008
38 2R7K AMZ 2.77008
39 1M0W ANP 2.88248
40 1T36 ADP 2.88248
41 3VSV XYS 2.88248
42 3VP6 HLD 2.88248
43 4OCV ANP 2.90237
44 1I7M PUT 2.99625
45 4NZN ANP 3.0303
46 4NZN 2OU 3.0303
47 3WO0 ADP 3.10421
48 3WO0 ALA 3.10421
49 2QK4 ATP 3.10421
50 3ETH ATP 3.10421
51 5DXT 5H5 3.10421
52 5FI4 5XV 3.10421
53 2VQD AP2 3.10421
54 2BMB PMM 3.10421
55 4UTG ANP 3.10421
56 5X80 SAL 3.125
57 4UWH JXM 3.1614
58 1OVD ORO 3.21543
59 1OVD FMN 3.21543
60 6G0X RAM GLC GLA NAG NDG NAG 3.32594
61 1D6Z HY1 3.32594
62 5WBF LAC 3.33333
63 3AKK ADP 3.38462
64 4LH7 1X8 3.40557
65 3ORQ ADP 3.44828
66 3BP1 GUN 3.44828
67 2AQX ATP 3.46021
68 4ZS4 ATP 3.58306
69 5ZCT ANP 3.59477
70 2QE4 JJ3 3.62903
71 1Z2P ACP 3.7037
72 1Z2P I3S 3.7037
73 3VRY B43 3.7694
74 5USZ SKE 3.80623
75 3X01 AMP 3.81679
76 3KRL KRL 3.8806
77 6GQM F8H 3.96341
78 5EQY 5RA 3.99003
79 5IGI ZIT 3.99113
80 5IGI GMP 3.99113
81 5OES ADP 3.99113
82 3PDT ADP 4
83 4CC6 L5Y 4.08805
84 3DZ6 PUT 4.11985
85 2PVF ACP 4.19162
86 3UDZ ADP 4.21286
87 3NW7 LGV 4.23453
88 5KO1 6UY 4.24028
89 5C1P DAL DAL 4.24837
90 5C1P ADP 4.24837
91 3HAV ATP 4.34783
92 3I0O ADP 4.42478
93 4CRL C1I 4.4335
94 3KA2 2NC 4.4335
95 2YRX AMP 4.43459
96 4O4F IHP 4.43548
97 4O4F ATP 4.43548
98 5YW5 ADE 4.46927
99 3RI1 3RH 4.47284
100 3W0O ADP 4.58453
101 3W0O HY0 4.58453
102 1XZ3 ICF 4.5977
103 5ML3 DL3 4.69799
104 3P7G MAN 4.79452
105 3VPC ADP 4.96454
106 3P7N FMN 5.03876
107 1PDZ PGA 5.06912
108 3TTI KBI 5.09978
109 6CGD AKN 5.2459
110 6CGD GNP 5.2459
111 5IH1 6BQ 5.29801
112 5IH1 GDP 5.29801
113 4O1P ANP 5.32151
114 3VPB ADP 5.35714
115 3VOT ADP 5.41176
116 4C5N PXL 5.43478
117 4C5N ACP 5.43478
118 2HGS ADP 5.54324
119 5TT6 ATP 5.58376
120 2OO8 RAJ 5.67823
121 3TPV ADE 5.68182
122 4MDH NAD 5.68862
123 4OAV ACP 5.76497
124 5YK1 ANP 5.76497
125 6A1G 9OL 5.83333
126 5AWM ANP 5.83756
127 4WHZ 3NL 5.97403
128 5MW8 ATP 5.9867
129 6FL8 TIY 5.9867
130 6FL8 ADP 5.9867
131 5VZ0 ADP 5.9867
132 1P6O HPY 6.21118
133 4IZY 1J2 6.23306
134 2V58 LZJ 6.23608
135 2D6M LBT 6.28931
136 2HK5 1BM 6.2963
137 4UX9 ANP 6.31868
138 4I94 ANP 6.33333
139 3PTG 932 6.33609
140 1JV1 UD1 6.43016
141 1KJ8 ATP 6.64962
142 1KJ8 GAR 6.64962
143 5C03 AGS 6.65188
144 4WOV 3SM 6.65188
145 3IES M24 6.65188
146 4AU8 Z3R 6.75676
147 4K33 ACP 6.76923
148 5MY8 RXZ 6.78851
149 5Y86 HRM 6.87361
150 1CBK ROI 6.875
151 6GWR FEW 6.98413
152 1XVB BHL 7.05882
153 5UR1 YY9 7.07396
154 5JKG 6LF 7.07396
155 4LRJ ANP 7.10059
156 1UNH IXM 7.21154
157 4JR7 GNP 7.48663
158 1OX5 1PR 7.5388
159 4OUC 5ID 8.12325
160 6G34 5ID 8.12325
161 5OMY 9YE 8.18414
162 6ES0 BW8 8.20189
163 3HZT J60 8.20399
164 2X2M X2M 8.28025
165 3M2W L8I 8.3612
166 1GPM AMP 8.42572
167 4IDT T28 8.42697
168 3PE2 E1B 8.60534
169 5TDF ADP 8.64198
170 3IGO ANP 8.64745
171 1W2D 4IP 8.67924
172 1W2D ADP 8.67924
173 4OH4 ANP 8.70871
174 5DMZ ADP 8.76712
175 3GC0 AMP 8.81459
176 1IOW PHY 8.82353
177 1IOW ADP 8.82353
178 1TQP ATP 8.86525
179 3PP0 03Q 8.87574
180 5T8O 76Z 8.88252
181 1XJD STU 8.98551
182 1V0O INR 9.02778
183 5EXK 5AD 9.06344
184 1TZD ADP 9.09091
185 3NWQ 2NC 9.09091
186 4XYM A12 9.13043
187 4XZ3 ACP 9.13043
188 4Y93 746 9.19283
189 1FFU CDP 9.20245
190 3D78 NBB 9.2437
191 2QF7 AGS 9.31264
192 2WD7 VGD 9.32836
193 5I35 ANP 9.41476
194 3EKK GS2 9.44625
195 3BU5 ATP 9.47712
196 1IR3 ANP 9.47712
197 5UIU 8CG 9.59752
198 1JPA ANP 9.61539
199 3C0G 3AM 9.68661
200 1K3A ACP 9.699
201 3E7O 35F 9.72222
202 4ONA UW1 9.97783
203 2QX0 PH2 10.0629
204 3O0G 3O0 10.0671
205 1ZTH ADP 10.0775
206 1ZP9 ATP 10.0775
207 2WEL K88 10.0917
208 4WNK 453 10.1996
209 2VPQ ANP 10.1996
210 5WNL STU 10.2339
211 2JLD AG1 10.2381
212 3Q60 ATP 10.2426
213 4F9C 0SX 10.2493
214 6C0T EE4 10.3746
215 2V7O DRN 10.4167
216 4DC2 ADE 10.4213
217 4NJH SAM 10.4348
218 4NJH 2K8 10.4348
219 6F3G CJN 10.5085
220 2PVN P63 10.5114
221 3MVH WFE 10.5263
222 2RIO ADP 10.5991
223 4L9I 8PR 10.643
224 4PNI KQQ 10.643
225 4R78 AMP 10.6796
226 4G17 0VN 10.9091
227 2VN9 GVD 10.9635
228 2BKK ADP 10.9848
229 3TM0 B31 11.0266
230 3TM0 ANP 11.0266
231 4FL3 ANP 11.0865
232 4U0I 0LI 11.1111
233 4WB7 ATP 11.1111
234 3VHE 42Q 11.1421
235 4ASE AV9 11.3314
236 4AT3 LTI 11.3712
237 3TKI S25 11.4551
238 3V8S 0HD 11.4634
239 5HCY 60D 11.4804
240 2HY0 306 11.4907
241 4YMJ 4EJ 11.5132
242 2H8H H8H 11.5299
243 4U98 ACP 11.5299
244 1Y57 MPZ 11.5299
245 3ZRM ZRM 11.5903
246 4EUU BX7 11.5987
247 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 11.6959
248 2JDR L20 11.6959
249 5EKO N17 11.8598
250 3LXN MI1 11.9497
251 4EWH T77 12
252 5TA6 79D 12.0112
253 3RE4 TO1 12.0155
254 2CSN CKI 12.1212
255 2YAB AMP 12.1884
256 3F7Z 34O 12.2857
257 2BPM 529 12.2977
258 6GZD LCI 12.2995
259 1U5R ATP 12.3563
260 4PU5 ANP 12.4169
261 5LI1 ANP 12.4294
262 6AC9 ANP 12.4324
263 4L3L 5FI 12.5
264 2YW2 ATP 12.5
265 5IH9 6BF 12.5373
266 4CFU 2WC 12.5413
267 4WB6 ATP 12.5714
268 5LI9 ACP 12.5714
269 3UIM ANP 12.5767
270 6GUE FB8 12.5828
271 4GJ3 0XP 12.5828
272 2WU6 DKI 12.5984
273 4BCQ TJF 12.6246
274 4BCM T7Z 12.6246
275 2YAK OSV 12.6316
276 4QTB 38Z 12.6316
277 4AG8 AXI 12.6582
278 4BCN T9N 12.6667
279 3AQV TAK 12.6812
280 4E1Z 0MX 12.7148
281 2XK9 XK9 12.7329
282 2XMY CDK 12.7517
283 5LMK 6ZK 12.7946
284 3FC2 IBI 12.8358
285 4YZC STU 12.8395
286 1RE8 BD2 12.8571
287 3IDB ANP 12.8571
288 2QCS ANP 12.8571
289 3FHI ANP 12.8571
290 4BFM ANP 12.8743
291 3E8N ATP 12.9032
292 3E8N VRA 12.9032
293 5W4W 9WG 12.9909
294 4KBA 1QM 12.9909
295 1PHK ATP 13.0872
296 4X7Q 3YR 13.141
297 4H3P ANP 13.2597
298 4H3Q ANP 13.2597
299 5BVE 4VG 13.2964
300 2GU8 796 13.3531
301 3CY2 MB9 13.3758
302 6CMJ F6J 13.3956
303 4Y85 499 13.5542
304 5X8I SQZ 13.5838
305 2WEI VGG 13.5889
306 4C2V YJA 13.6364
307 3H9R TAK 13.6364
308 2R5T ANP 13.6729
309 5OKT 9XK 13.6943
310 2PZI AXX 13.7472
311 3LXK MI1 13.7615
312 4BHN BH9 13.7725
313 3GQI ACP 13.8037
314 5EFQ ADP 13.8329
315 6G33 5ID 13.8643
316 3C1X CKK 13.941
317 3GGF GVD 13.9535
318 2F2U M77 14.1791
319 3FHR P4O 14.2857
320 5Y80 IRE 14.377
321 4P5Z Q7M 14.4044
322 5MJA 7O3 14.4262
323 4Q5H ANP 14.4737
324 3SLS ANP 14.4737
325 4AUA 4AU 14.658
326 5FBN 5WF 14.7601
327 3ORK AGS 14.791
328 1OPK P16 14.8559
329 6GIN IR2 14.9502
330 3ALN ANP 14.9847
331 4M69 ANP 15.016
332 6GU6 1QK 15.2318
333 5HQ0 LZ9 15.2318
334 4N70 2HX 15.2439
335 6E2O S0L 15.2542
336 4U44 3D9 15.3614
337 3KN5 ANP 15.3846
338 4E93 GUI 15.3846
339 4QMN DB8 15.4839
340 5A6N U7E 15.5477
341 1Q8Y ADE 15.5496
342 1Q8Y ADP 15.5496
343 1OUK 084 15.5738
344 4LOO SB4 15.7895
345 5DRB 5FJ 15.8076
346 4OTH DRN 15.8358
347 4I6H 1C8 15.9091
348 5HES 032 15.9609
349 3TXO 07U 16.1473
350 4UXL 5P8 16.1491
351 6CQF F97 16.1616
352 4Y8D 49J 16.1765
353 6EAC ANP 16.1863
354 3DAK ANP 16.2069
355 2VZ6 FEF 16.2939
356 5EOB 5QQ 16.3009
357 5TO8 7FM 16.3121
358 6FYV 3NG 16.3205
359 1CM8 ANP 16.3488
360 3GC8 B45 16.4865
361 5JZJ AN2 16.4983
362 5WO4 B7V 16.5563
363 2F57 23D 16.7192
364 4YZN 4K5 16.7247
365 6C7Y ADP 16.7832
366 5U6C 7YS 16.8254
367 5DEY 59T 16.835
368 1ZY5 ANP 17.1617
369 4UAL 3FV 17.1838
370 5AX9 4KT 17.2078
371 4RFM 3P6 17.2932
372 5VC5 96M 17.301
373 4C2W ANP 17.3077
374 3DLS ADP 17.3134
375 4FG8 ATP 17.4603
376 6FYL 3NG 17.6309
377 5CEO 50D 17.6667
378 3SRV S19 18.0505
379 2Y6O 1N1 18.2131
380 4F4P 0SB 18.315
381 4WNP 3RJ 18.4669
382 3BZ3 YAM 18.4783
383 3G5D 1N1 18.5315
384 6BFN DL1 18.7134
385 2J7T 274 18.8742
386 2ZV2 609 19.1275
387 2B9F ADP 19.2635
388 5G1X ADP 19.2982
389 5L8L ADP 19.2982
390 5GLT BGC GAL NAG GAL 19.3662
391 5LXM ADP 19.4346
392 5ODT ADP 19.4346
393 5H2U 1N1 19.4757
394 1U59 STU 19.5122
395 3GNI ATP 19.5373
396 2B9J ADP 19.5467
397 2B9I ADP 19.5467
398 2B9H ADP 19.5467
399 6CZ3 FLJ 19.697
400 4NFN 2KC 20.0647
401 3PLS ANP 20.1342
402 2OFV 242 20.2166
403 5EW9 5VC 20.2952
404 5YF9 NIO 20.354
405 4G31 0WH 20.4013
406 3E5A VX6 20.5224
407 2QLU ADE 20.7006
408 4NM5 ADP 20.8333
409 5UPK ANP 21.0983
410 4KS7 X4Z 21.2329
411 4NW6 2NS 21.3622
412 5JGA 6KC 21.9048
413 2XVD AS6 22.1854
414 4Y0X ADP 22.4
415 3KMW ATP 22.4806
416 4CLI 5P8 22.9358
417 4NST ADP 23.0769
418 5M06 ADP 23.1884
419 5UKL SIX 23.2816
420 3PVW QRX 23.2816
421 4IJP 1EH 24.3017
422 4BTK DTQ 24.6291
423 5JFS 6K0 24.6753
424 5XVG 8FX 24.9147
425 5LVP ATP 25.0804
426 3RWP ABQ 25.4019
427 5NKB 8ZT 26.1438
428 2Z7R STU 26.4798
429 5QIN J2V 26.8987
430 4XV1 904 27.3973
431 5HVJ ANP 27.619
432 5VCV 1N1 27.6527
433 4CQE CQE 27.6978
434 1O9U ADZ 27.7778
435 5DH3 5BS 28.254
436 4USF 6UI 28.6184
437 2WQN ADP 29.0323
438 1VJY 460 29.0429
439 6BXI ANP 29.1291
440 1BYG STU 29.1367
441 2A19 ANP 29.5775
442 3SXS PP2 30.2239
443 3HMO STU 30.7018
444 4CSV STI 31.6364
445 4A4X JUP 33.3333
446 4TWP AXI 34.3173
447 5EH0 5NW 36.0465
448 5N87 N66 36.1022
449 5EYK 5U5 44.0678
Pocket No.: 2; Query (leader) PDB : 5CKW; Ligand: ANP; Similar sites found with APoc: 12
This union binding pocket(no: 2) in the query (biounit: 5ckw.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 1T9D FAD 1.99557
2 1YBH FAD 2.21729
3 1D6H COA 2.84238
4 3RG9 WRA 3.75
5 1BZY IMU 4.14747
6 5A89 FMN 5.12821
7 1NVM NAD 7.82609
8 3G6K POP 8.11688
9 3G6K FAD 8.11688
10 4JWJ SAH 8.41584
11 1N62 MCN 9.03614
12 4NG2 OHN 15.0442
APoc FAQ
Feedback