Receptor
PDB id Resolution Class Description Source Keywords
5DG2 1.61 Å NON-ENZYME: BINDING SUGAR BINDING PROTEIN - HUMAN GALECTIN-2 (DIMER) HOMO SAPIENS HUMAN GALECTIN-2 SUGAR BINDING PROTEIN
Ref.: HUMAN GALECTIN-2 INTERACTS WITH CARBOHYDRATES AND P NON-CLASSICALLY: NEW INSIGHT FROM X-RAY CRYSTALLOGR HEMAGGLUTINATION. ACTA BIOCHIM. BIOPHYS. SIN. V. 48 939 2016 (SHANGHAI)
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GAL GLC B:201;
Valid;
none;
submit data
342.297 n/a O(C1O...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5DG2 1.61 Å NON-ENZYME: BINDING SUGAR BINDING PROTEIN - HUMAN GALECTIN-2 (DIMER) HOMO SAPIENS HUMAN GALECTIN-2 SUGAR BINDING PROTEIN
Ref.: HUMAN GALECTIN-2 INTERACTS WITH CARBOHYDRATES AND P NON-CLASSICALLY: NEW INSIGHT FROM X-RAY CRYSTALLOGR HEMAGGLUTINATION. ACTA BIOCHIM. BIOPHYS. SIN. V. 48 939 2016 (SHANGHAI)
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 473 families.
1 5DG2 - GAL GLC n/a n/a
2 5EWS - GAL BGC n/a n/a
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 355 families.
1 5DG2 - GAL GLC n/a n/a
2 5EWS - GAL BGC n/a n/a
50% Homology Family (94)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 272 families.
1 5NF9 Kd = 4.7 uM 8VW C22 H32 N2 O12 CC(=O)N[C@....
2 5E8A Kd = 0.034 uM 5KS C28 H30 F2 N6 O8 S c1cc(ccc1c....
3 1A3K - GAL NAG n/a n/a
4 3T1M Kd = 0.91 mM DQT C23 H27 N O7 Cc1ccc(cc1....
5 4LBL Kd = 11 uM BGC SIA GAL n/a n/a
6 2NMN Kd = 260 uM GAL BGC n/a n/a
7 4R9B - LAT C12 H22 O11 C([C@@H]1[....
8 2NN8 Kd = 260 uM LAT C12 H22 O11 C([C@@H]1[....
9 4JC1 Kd = 50 uM TDG C12 H22 O10 S C([C@@H]1[....
10 4R9A - LAT C12 H22 O11 C([C@@H]1[....
11 5EXO - 5SY C19 H22 O9 CC(=O)O[C@....
12 5E88 Kd = 0.065 uM 5KT C24 H28 N6 O8 S3 c1cscc1c2c....
13 4R9D - LAT C12 H22 O11 C([C@@H]1[....
14 1KJL Kd = 67 uM GAL NAG n/a n/a
15 3T1L Kd = 0.55 mM MQT C17 H22 O8 Cc1ccc(cc1....
16 2XG3 Kd = 18.2 uM UNU GAL NAG n/a n/a
17 4LBJ Kd = 0.39 uM GAL NAG GAL BGC n/a n/a
18 4R9C - LAT C12 H22 O11 C([C@@H]1[....
19 3ZSJ Kd = 231 uM LAT C12 H22 O11 C([C@@H]1[....
20 4LBM Kd = 0.97 uM BGC GAL NAG GAL n/a n/a
21 1KJR Kd = 0.88 uM BEK GAL NAG n/a n/a
22 3AYE - LAT C12 H22 O11 C([C@@H]1[....
23 5E89 Kd = 0.014 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
24 4LBO Kd = 1.7 uM BGC GAL SIA n/a n/a
25 2NMO Kd = 260 uM GAL BGC n/a n/a
26 3AYC Kd = 57 uM GAL NGA GAL BGC SIA n/a n/a
27 4JCK Kd = 4.3 mM 1LL C12 H22 O10 S C([C@@H]1[....
28 5NFA Kd = 5.6 uM 8VQ C24 H36 N2 O12 CC(=O)N[C@....
29 4LBK Kd = 0.32 uM GAL NAG GAL BGC n/a n/a
30 4RL7 - LAT C12 H22 O11 C([C@@H]1[....
31 3AYD Kd = 65 uM NPO A2G GAL n/a n/a
32 4LBN Kd = 0.65 uM GLC GAL NAG GAL n/a n/a
33 2D6N - GAL NAG n/a n/a
34 2D6M - LBT C12 H22 O11 C([C@@H]1[....
35 2D6O - NAG GAL GAL NAG n/a n/a
36 4XBN Kd = 93 uM GAL NAG n/a n/a
37 5H9R Kd = 0.84 uM TGZ C20 H26 F N3 O9 S c1cc(cc(c1....
38 5H9P Kd = 0.068 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
39 5DG2 - GAL GLC n/a n/a
40 5EWS - GAL BGC n/a n/a
41 4XBL Kd = 340 uM GAL NAG n/a n/a
42 4Y24 Kd = 0.22 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
43 3T2T - MQT C17 H22 O8 Cc1ccc(cc1....
44 3OY8 Kd = 220 uM GAL GCO n/a n/a
45 2EAL - GAL NGA A2G n/a n/a
46 2ZHL Kd = 3 uM NAG GAL GAL NAG n/a n/a
47 2ZHK Kd = 3 uM NAG GAL GAL NAG n/a n/a
48 2ZHN - NAG GAL NAG GAL GAL NAG n/a n/a
49 2ZHM - NAG GAL GAL NAG GAL n/a n/a
50 2EAK - LBT C12 H22 O11 C([C@@H]1[....
51 3WLU - LSE C18 H36 O10 Se Si C[Si](C)(C....
52 5H9S Kd = 87 uM TGZ C20 H26 F N3 O9 S c1cc(cc(c1....
53 5H9Q Kd = 38 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
54 4XBQ Kd = 270 uM GAL NAG n/a n/a
55 5T7S Kd = 3.1 uM LBT C12 H22 O11 C([C@@H]1[....
56 4BMB Ka = 13000 M^-1 LAT C12 H22 O11 C([C@@H]1[....
57 5T7I Kd = 0.33 uM LAT NAG GAL n/a n/a
58 3VKO - SIA GAL NAG n/a n/a
59 4BME Ka = 13000 M^-1 LBT C12 H22 O11 C([C@@H]1[....
60 5T7T Kd = 2.1 uM GAL NAG n/a n/a
61 3I8T Kd = 600 uM LBT C12 H22 O11 C([C@@H]1[....
62 3WV6 - GAL BGC n/a n/a
63 3NV2 - GAL NDG n/a n/a
64 3NV4 - SIA GAL BGC n/a n/a
65 3NV3 - GAL NAG MAN n/a n/a
66 3WUD Kd = 41 uM GLC GAL n/a n/a
67 3GAL - 1GN C6 H13 N O5 C([C@@H]1[....
68 4UW6 - VV7 C69 H73 N20 O39 [H]1c2c(cc....
69 2GAL - GAL C6 H12 O6 C([C@@H]1[....
70 4GAL - GAL BGC n/a n/a
71 4UW3 - 50G C31 H50 N10 O18 c1c(nnn1[C....
72 4UW4 - 4S0 C49 H80 N10 O33 c1c(nnn1[C....
73 3ZXE Kd = 450 uM PGZ C22 H28 N O8 P S Cc1ccc(cc1....
74 5GAL - NAG GAL n/a n/a
75 4UW5 - 4S0 C49 H80 N10 O33 c1c(nnn1[C....
76 1GAN - NDG GAL n/a n/a
77 1A78 - TDG C12 H22 O10 S C([C@@H]1[....
78 5DUW Kd = 510 uM 5GO C12 H22 O14 S C([C@@H]1[....
79 5DUV Kd = 1300 uM LAT C12 H22 O11 C([C@@H]1[....
80 5DUX Kd = 380 uM LAT FUC n/a n/a
81 4WVV - LBT C12 H22 O11 C([C@@H]1[....
82 4WVW - SLT C23 H39 N O19 CC(=O)N[C@....
83 4YLZ Kd = 270 uM LAT NAG GAL n/a n/a
84 5CBL - LAT C12 H22 O11 C([C@@H]1[....
85 4YM2 Kd = 1400 uM SGA BGC n/a n/a
86 4YM3 Kd = 1900 uM LAT C12 H22 O11 C([C@@H]1[....
87 4YM1 Kd = 580 uM LAT FUC n/a n/a
88 1IS4 - LAT C12 H22 O11 C([C@@H]1[....
89 1WLD - GAL BGC n/a n/a
90 5NFB Kd = 0.77 uM 8VT C30 H40 N2 O13 CC(=O)N[C@....
91 5NF7 Kd = 37.5 uM 8VZ C16 H28 N2 O11 CC(=O)N[C@....
92 1SLB - NAG MAN GAL MAN MAN NAG GAL n/a n/a
93 1SLT - NDG GAL n/a n/a
94 1SLA - NAG MAN GAL BMA NAG MAN NAG GAL n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GAL GLC; Similar ligands found: 339
No: Ligand ECFP6 Tc MDL keys Tc
1 LBT 1 1
2 GLC BGC 1 1
3 MAL MAL 1 0.970588
4 BGC GLC 1 1
5 CBI 1 1
6 GAL BGC 1 1
7 CBK 1 1
8 BGC BMA 1 1
9 N9S 1 1
10 GLA GLA 1 1
11 BGC GAL 1 1
12 GAL GLC 1 1
13 GLC GAL 1 1
14 BMA BMA 1 1
15 GLA GAL 1 1
16 BMA GAL 1 1
17 LAT 1 1
18 MAB 1 1
19 MAL 1 1
20 B2G 1 1
21 CEX 0.909091 1
22 BGC GLC GLC GLC GLC 0.909091 1
23 GLC GLC GLC GLC GLC 0.909091 1
24 CTR 0.909091 1
25 MTT 0.909091 1
26 CE5 0.909091 1
27 BMA BMA BMA BMA BMA 0.909091 1
28 CTT 0.909091 1
29 CT3 0.909091 1
30 GLC GLC GLC GLC GLC GLC GLC 0.909091 1
31 BGC GLC GLC GLC GLC GLC GLC 0.909091 1
32 BGC BGC BGC GLC 0.909091 1
33 CEY 0.909091 1
34 MAN MAN BMA BMA BMA BMA 0.909091 1
35 BMA BMA BMA 0.909091 1
36 B4G 0.909091 1
37 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.909091 1
38 GLC GAL GAL 0.909091 1
39 GLA GAL GLC 0.909091 1
40 GAL GAL GAL 0.909091 1
41 MAN BMA BMA BMA BMA 0.909091 1
42 MLR 0.909091 1
43 CE8 0.909091 1
44 MT7 0.909091 1
45 CE6 0.909091 1
46 GLC BGC BGC BGC BGC BGC 0.909091 1
47 GLC GLC BGC 0.909091 1
48 GLC BGC BGC 0.909091 1
49 GLC BGC GLC 0.909091 1
50 BMA MAN BMA 0.909091 1
51 GLC GLC BGC GLC GLC GLC GLC 0.909091 1
52 BGC GLC GLC 0.909091 1
53 BGC GLC GLC GLC 0.909091 1
54 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.909091 1
55 DXI 0.909091 1
56 BMA BMA BMA BMA BMA BMA 0.909091 1
57 GLC GLC GLC GLC GLC GLC GLC GLC 0.909091 1
58 GLC BGC BGC BGC BGC 0.909091 1
59 BGC BGC BGC BGC BGC BGC 0.909091 1
60 MAN BMA BMA 0.909091 1
61 MAN BMA BMA BMA BMA BMA 0.833333 0.970588
62 BMA BMA BMA BMA BMA BMA MAN 0.833333 0.970588
63 GLA GAL GAL 0.816327 1
64 GLA GAL BGC 0.816327 1
65 BGC BGC BGC BGC 0.754717 1
66 BGC BGC BGC BGC BGC BGC BGC BGC 0.754717 1
67 BMA BMA GLA BMA BMA 0.689655 1
68 LAT GLA 0.680851 1
69 GLC GLC GLC BGC 0.672414 1
70 BGC BGC GLC 0.660377 1
71 U63 0.647059 0.891892
72 DR5 0.64 0.942857
73 MMA MAN 0.64 0.942857
74 GLA EGA 0.634615 0.942857
75 BMA BMA MAN 0.615385 0.970588
76 GAL FUC 0.615385 0.941176
77 BGC BGC 0.612245 1
78 MAN MAN 0.612245 1
79 2M4 0.612245 1
80 GLC GAL FUC 0.610169 0.970588
81 GLC GLC GLC GLC GLC GLC 0.610169 1
82 FUC LAT 0.610169 0.970588
83 FUC GAL GLC 0.610169 0.970588
84 BGC GAL FUC 0.610169 0.970588
85 LAT FUC 0.610169 0.970588
86 BGC GLA GAL FUC 0.609375 0.970588
87 GAL NAG GAL BGC 0.606061 0.733333
88 LAT NAG GAL 0.606061 0.733333
89 GLC GLC BGC XYS BGC XYS 0.606061 0.942857
90 BGC GAL NAG GAL 0.606061 0.733333
91 MAN GLC 0.6 1
92 LB2 0.6 1
93 M3M 0.6 1
94 SGA BGC 0.6 0.702128
95 MAL EDO 0.592593 0.942857
96 BGC BGC BGC XYS GAL 0.588235 0.942857
97 XYS BGC BGC XYS BGC XYS BGC BGC BGC 0.588235 0.942857
98 GLC GAL NAG GAL 0.588235 0.733333
99 BGC BGC BGC XYS BGC BGC 0.588235 0.942857
100 XYS BGC BGC BGC BGC XYS BGC BGC BGC 0.588235 0.942857
101 NGA GAL BGC 0.587302 0.733333
102 TRE 0.581395 1
103 ABD 0.57971 0.75
104 NDG GAL 0.578947 0.733333
105 GAL NDG 0.578947 0.733333
106 5GO 0.578947 0.66
107 NLC 0.578947 0.733333
108 DEL 0.574074 0.970588
109 GAL NGA GLA BGC GAL 0.571429 0.733333
110 MVP 0.571429 0.733333
111 GAL BGC BGC XYS 0.569231 0.942857
112 GLC GLC FRU 0.569231 0.868421
113 BMA MAN 0.566038 0.914286
114 GLC GLC XYP 0.557377 1
115 BGC BGC XYS BGC 0.552239 0.942857
116 NAG GAL BGC 0.552239 0.733333
117 GLA GAL BGC 5VQ 0.551724 0.891892
118 G2F BGC BGC BGC BGC BGC 0.55 0.868421
119 GLA MBG 0.54902 0.942857
120 GLC ACI GLD GLC 0.547945 0.785714
121 GLC G6D ACI GLC 0.547945 0.785714
122 GLC ACI G6D BGC 0.547945 0.785714
123 GLC G6D ADH GLC 0.547945 0.785714
124 GLC BGC BGC BGC 0.545455 1
125 BGC BGC BGC ASO BGC BGC ASO 0.545455 1
126 GLC BGC BGC BGC BGC BGC BGC 0.545455 1
127 BGC BGC BGC 0.545455 1
128 BGC BGC BGC GLC BGC BGC 0.545455 1
129 BGC BGC BGC BGC BGC 0.545455 1
130 MAN MAN BMA 0.535714 1
131 NGA GLA GAL BGC 0.535211 0.733333
132 BMA MAN MAN 0.534483 1
133 GAL BGC BGC BGC XYS BGC XYS 0.533333 0.942857
134 BGC BGC BGC XYS BGC XYS GAL 0.533333 0.942857
135 GLC BGC BGC XYS BGC XYS XYS 0.528571 0.942857
136 BGC BGC BGC XYS BGC XYS XYS 0.528571 0.942857
137 BGC BGC XYS BGC XYS BGC XYS 0.528571 0.942857
138 GLA GAL GLC NBU 0.52459 0.846154
139 FUC BGC GAL 0.52459 0.970588
140 GLC ACI GLD GAL 0.519481 0.733333
141 GLC ACI G6D GLC 0.519481 0.733333
142 GLC GLC G6D ACI GLC GLC GLC 0.519481 0.785714
143 GLC BGC BGC BGC XYS BGC XYS XYS 0.513514 0.916667
144 DOM 0.509091 0.942857
145 GAL GAL SO4 0.508197 0.702128
146 DMU 0.507937 0.785714
147 LMT 0.507937 0.785714
148 LMU 0.507937 0.785714
149 G2I 0.507937 0.767442
150 G3I 0.507937 0.767442
151 OXZ BGC BGC 0.507937 0.6875
152 UMQ 0.507937 0.785714
153 GLC AGL GLC HMC 0.506329 0.717391
154 BGC BGC XYS BGC GAL XYS BGC XYS GAL 0.506329 0.942857
155 GLC BGC BGC XYS BGC XYS XYS GAL GAL 0.506329 0.942857
156 GAL BGC BGC BGC XYS XYS 0.506329 0.942857
157 GAL XYS XYS BGC BGC BGC XYS GAL BGC 0.506329 0.942857
158 GLC BGC BGC XYS BGC XYS XYS GAL 0.506329 0.942857
159 NAG GAL GAL 0.5 0.733333
160 SOR GLC GLC 0.5 0.970588
161 GAL GAL GLC EMB MEC 0.5 0.622642
162 FMO 0.5 0.868421
163 MAN BMA NAG 0.5 0.733333
164 GLA GAL NAG 0.5 0.733333
165 8VZ 0.5 0.673469
166 GLC GLC ACI G6D GLC GLC 0.493827 0.733333
167 GLC GLC AGL HMC GLC 0.493827 0.733333
168 GLC GLC DAF BGC 0.493827 0.733333
169 AAO 0.493827 0.733333
170 ARE 0.493827 0.733333
171 ACR GLC GLC GLC 0.493827 0.733333
172 GLC GLC XYS 0.492308 0.970588
173 CGC 0.491525 0.941176
174 5QP 0.491228 0.885714
175 MDM 0.490909 0.942857
176 RZM 0.490909 0.688889
177 M13 0.490909 0.942857
178 GAL MBG 0.490909 0.942857
179 GLC GLC GLC G6D ADH GLC 0.487805 0.6875
180 BGC BGC G2F SHG 0.485714 0.846154
181 MAN NAG GAL 0.485294 0.733333
182 GAL NAG MAN 0.485294 0.733333
183 6UZ 0.484848 0.846154
184 SOR GLC GLC GLC 0.484848 0.970588
185 LAG 0.484848 0.6
186 MAN MNM 0.482759 0.75
187 GAL BGC NAG GAL 0.478873 0.733333
188 10M 0.477612 0.733333
189 GTM BGC BGC 0.477612 0.868421
190 MAN MAN MAN MAN 0.476923 1
191 MAN MAN BMA MAN 0.476923 1
192 GLA GAL NAG FUC GAL GLC 0.47619 0.717391
193 NAG BMA 0.47619 0.653061
194 GAL NGA 0.47541 0.733333
195 GAL A2G 0.47541 0.733333
196 A2G GAL 0.47541 0.733333
197 BMA GLA 0.472727 1
198 LAK 0.472727 1
199 GAL GAL 0.472727 1
200 GLA GLC 0.472727 1
201 MLB 0.472727 1
202 GLA BMA 0.472727 1
203 BGC GLA 0.472727 1
204 MAN BMA 0.472727 1
205 GLA BGC 0.472727 1
206 NPJ 0.470588 0.622642
207 FUC GAL NAG GAL BGC 0.469136 0.717391
208 MAN MAN MAN GLC 0.46875 1
209 ABL 0.466667 0.702128
210 BMA FRU 0.465517 0.842105
211 FRU GAL 0.465517 0.842105
212 NOY BGC 0.465517 0.75
213 TM6 0.463768 0.916667
214 BGC SGC BGC SGC BGC SGC BGC SGC 0.463768 0.916667
215 LSE 0.462687 0.6875
216 GLA GLA FUC 0.460317 0.970588
217 FUC GAL GLA 0.460317 0.970588
218 GAL GAL FUC 0.460317 0.970588
219 GLA GAL FUC 0.460317 0.970588
220 FUC GLA GLA 0.460317 0.970588
221 DAF BGC 0.458333 0.785714
222 DAF GLC 0.458333 0.785714
223 IFM BMA 0.457627 0.744186
224 BGC OXZ 0.457627 0.666667
225 IFM BGC 0.457627 0.744186
226 BMA IFM 0.457627 0.744186
227 9MR 0.457627 0.744186
228 GLO GLC GLC 0.457143 0.942857
229 RCB 0.457143 0.622642
230 GLC GLC GLC GLC GLC BGC 0.45614 1
231 GLC GLC GLC 0.45614 1
232 GLC GLC GLC GLC BGC 0.45614 1
233 MAN MAN MAN 0.45614 1
234 GLC 0.454545 0.848485
235 BMA 0.454545 0.848485
236 GXL 0.454545 0.848485
237 WOO 0.454545 0.848485
238 GIV 0.454545 0.848485
239 GAL 0.454545 0.848485
240 MAN 0.454545 0.848485
241 BGC 0.454545 0.848485
242 ALL 0.454545 0.848485
243 GLA 0.454545 0.848485
244 GLC GLC GLC GLC 0.453125 1
245 MGL SGC GLC GLC 0.450704 0.868421
246 CM5 0.450704 0.891892
247 MAN MAN MAN BMA MAN 0.450704 1
248 BGC BGC SGC MGL 0.450704 0.868421
249 GLC DMJ 0.45 0.727273
250 A2G GAL BGC FUC 0.45 0.717391
251 GLC GLC GLC PO4 SGC GLC 0.45 0.673469
252 NOJ GLC 0.45 0.727273
253 PA1 GCS 0.448276 0.804878
254 GCS GCS 0.448276 0.804878
255 M5S 0.447761 1
256 MAN BMA MAN MAN MAN 0.447761 1
257 GLC GLC XYS XYS 0.447761 0.914286
258 DAF BGC GLC 0.447368 0.785714
259 TXT 0.447368 0.767442
260 GAC 0.447368 0.767442
261 DAF GLC GLC 0.447368 0.785714
262 ACI GLD GLC GAL 0.447368 0.785714
263 GLC GAL NAG GAL FUC FUC 0.447059 0.702128
264 BGC GAL NAG GAL FUC FUC 0.447059 0.702128
265 GAL NAG GAL NAG GAL NAG 0.445946 0.673469
266 NAG GAL GAL NAG GAL 0.445946 0.6875
267 NAG GAL GAL NAG 0.445946 0.6875
268 MA4 0.444444 0.891892
269 QV4 0.444444 0.733333
270 GLO GLC GLC GLC 0.444444 0.942857
271 MAN DGO 0.440678 0.914286
272 3SA 0.44 0.733333
273 Z6J 0.439024 0.742857
274 AHR 0.439024 0.742857
275 32O 0.439024 0.742857
276 FUB 0.439024 0.742857
277 RIB 0.439024 0.742857
278 T6P 0.438596 0.767442
279 GYP 0.4375 0.857143
280 AMG 0.4375 0.857143
281 MMA 0.4375 0.857143
282 MBG 0.4375 0.857143
283 4MU BGC BGC 0.434211 0.767442
284 ISX 0.433333 0.761905
285 MAN 7D1 0.431034 0.888889
286 QPS 0.43038 0.733333
287 ACR 0.43038 0.733333
288 4MU BGC BGC BGC BGC 0.428571 0.767442
289 GAL MGC 0.428571 0.702128
290 GAL NGA A2G 0.426471 0.673469
291 FUC NAG GAL 0.422535 0.717391
292 FUC NDG GAL 0.422535 0.717391
293 GAL NAG FUC 0.422535 0.717391
294 GAL NDG FUC 0.422535 0.717391
295 KHO 0.421053 0.888889
296 HMC AGL GLC 0.421053 0.717391
297 GCS GCS GCS GCS GCS 0.419355 0.804878
298 GCS GCS GCS GCS GCS GCS 0.419355 0.804878
299 GCS GCS GCS 0.419355 0.804878
300 GAL NAG GAL 0.418919 0.702128
301 GAL NGT 0.41791 0.66
302 P3M 0.41791 0.767442
303 NGT GAL 0.41791 0.66
304 ACR GLC GLC GLC GLC 0.417722 0.733333
305 ACR GLC 0.417722 0.733333
306 A2G GAL NAG FUC GAL GLC 0.417582 0.673469
307 GLC GAL NAG GAL FUC A2G 0.417582 0.673469
308 TUR 0.416667 0.842105
309 BTU 0.416667 0.842105
310 GLA MAN ABE 0.414286 0.916667
311 NAG NDG BMA 0.413333 0.634615
312 NAG NAG BMA 0.413333 0.634615
313 AHR AHR AHR 0.410714 0.857143
314 FUB AHR AHR 0.410714 0.857143
315 GLF B8D 0.409836 0.775
316 VAM 0.409836 0.868421
317 ACI G6D GLC ACI G6D BGC 0.409639 0.75
318 BGC GLC AC1 GLC GLC GLC AC1 0.409639 0.75
319 AC1 GLC AC1 BGC 0.409639 0.75
320 DAF GLC DAF GLC GLC 0.409639 0.75
321 ACI GLD GLC GLC GLC ACI GLD GLC GAL 0.409639 0.75
322 ACI GLD GLC ACI G6D BGC 0.409639 0.75
323 MAN MMA MAN 0.409091 0.942857
324 AHR AHR 0.407407 0.857143
325 FUB AHR 0.407407 0.857143
326 NAG BMA MAN MAN MAN MAN 0.407407 0.733333
327 G6D GLC ACI GLD GLC ACI GLD GLC BGC 0.406977 0.680851
328 4U0 0.406593 0.66
329 GLA MAN RAM ABE 0.405063 0.891892
330 BGC BGC SSG PIH 0.405063 0.767442
331 M1P 0.403846 0.697674
332 GL1 0.403846 0.697674
333 XGP 0.403846 0.697674
334 G1P 0.403846 0.697674
335 MAN IFM 0.403226 0.761905
336 GLC IFM 0.403226 0.761905
337 XZZ BGC BGC 0.402439 0.702128
338 ACG 0.402299 0.695652
339 FUC GAL 0.4 0.941176
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5DG2; Ligand: GAL GLC; Similar sites found: 233
This union binding pocket(no: 1) in the query (biounit: 5dg2.bio1) has 8 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3MTX PGT 0.000323 0.47716 None
2 4ZSI GLP 0.001471 0.46399 None
3 2GJ5 VD3 0.001003 0.45773 None
4 2BWA GLC BGC 0.001388 0.4537 None
5 2BOS GLA GAL 0.0004401 0.43969 None
6 4QRH 0O2 0.002342 0.43637 None
7 2BOS GLA GAL GLC 0.0006681 0.42598 None
8 4ZSI 4R1 0.005412 0.42327 None
9 4XBT 3ZQ 0.01814 0.41439 None
10 4XBT FLC 0.01768 0.41313 None
11 3AKK ADP 0.01928 0.40654 None
12 3X1Z GNP 0.02138 0.40594 None
13 4KVG GTP 0.02091 0.40411 None
14 5C8W PCG 0.007404 0.40061 None
15 1NE6 SP1 0.004217 0.42764 1.48148
16 3TYZ PAB 0.0359 0.41392 1.48148
17 5ISY NAD 0.004239 0.40504 1.48148
18 2QL9 CIT 0.001943 0.43617 2.06186
19 1TT8 PHB 0.00005868 0.55352 2.22222
20 5EOB 5QQ 0.0006394 0.49568 2.22222
21 4WUJ FMN 0.005747 0.41776 2.22222
22 2IRY DGT 0.004566 0.41072 2.22222
23 4Q0L V14 0.006993 0.40979 2.22222
24 2CER PGI 0.00456 0.44852 2.24949
25 2QZT PLM 0.006601 0.44945 2.7027
26 1I82 BGC BGC 0.00009394 0.48829 2.96296
27 2AG4 OLA 0.00345 0.4576 2.96296
28 2AG4 LP3 0.003727 0.4576 2.96296
29 3T1A 5MA 0.0009768 0.45191 2.96296
30 2ZRU FMN 0.02033 0.4109 2.96296
31 3AAQ ARU 0.02322 0.40786 2.96296
32 4ORM 2V6 0.01699 0.40439 2.96296
33 4ORM ORO 0.01699 0.40439 2.96296
34 4ORM FMN 0.01699 0.40439 2.96296
35 2R40 EPH 0.01605 0.4022 2.96296
36 4R38 RBF 0.005983 0.40147 2.96296
37 4BVM PLM 0.009515 0.40094 3.00752
38 4BVM VCA 0.01012 0.40094 3.00752
39 3H22 B53 0.008482 0.44294 3.0303
40 5FXD H7Y 0.00006459 0.5475 3.7037
41 1GP6 QUE 0.0007342 0.46532 3.7037
42 1GP6 SIN 0.0006892 0.46532 3.7037
43 1GP6 DH2 0.0006892 0.46532 3.7037
44 5IH9 6BF 0.003108 0.46448 3.7037
45 5KJZ PCG 0.002804 0.44667 3.7037
46 2AXR ABL 0.001302 0.44506 3.7037
47 4ZLU 4PW 0.01551 0.43747 3.7037
48 4ZLU ADP 0.01551 0.43747 3.7037
49 5DXI TRE 0.002222 0.42635 3.7037
50 1LVG 5GP 0.002349 0.42634 3.7037
51 3UN3 G16 0.002897 0.42059 3.7037
52 3BXO UPP 0.007372 0.41958 3.7037
53 1GQG DCD 0.003956 0.4172 3.7037
54 4L6H MTX 0.02035 0.41622 3.7037
55 5FBN 5WF 0.02042 0.4141 3.7037
56 3W68 VIV 0.01258 0.40942 3.7037
57 3GNP SOG 0.007143 0.40532 3.7037
58 4WOE ADP 0.00657 0.40329 3.7037
59 3TAY MN0 0.00507 0.40061 3.7037
60 1R5L VIV 0.0166 0.40042 3.7037
61 5KWY C3S 0.002763 0.44387 3.7594
62 3K3K A8S 0.001645 0.43714 4.2654
63 5NCF 8T5 0.001602 0.41324 4.42478
64 3G08 FEE 0.005647 0.46415 4.44444
65 1Q79 3AT 0.001274 0.44986 4.44444
66 4XCB HY0 0.005553 0.44872 4.44444
67 2CET PGI 0.004569 0.44502 4.44444
68 3L9R L9R 0.003796 0.44248 4.44444
69 5IXG OTP 0.004243 0.43891 4.44444
70 5N87 N66 0.00514 0.43346 4.44444
71 3HMO STU 0.002297 0.42884 4.44444
72 4NMC FAD 0.02358 0.42743 4.44444
73 4NMC 2OP 0.02277 0.42743 4.44444
74 3W8X FAD 0.0149 0.42723 4.44444
75 1E96 GTP 0.01805 0.42256 4.44444
76 5LUN ARG 0.01413 0.42094 4.44444
77 5LUN OGA 0.01413 0.42094 4.44444
78 1YVD GNP 0.01611 0.41998 4.44444
79 1Z0J GTP 0.01885 0.41534 4.44444
80 5BVE 4VG 0.01779 0.41477 4.44444
81 5KO1 6UY 0.008222 0.41344 4.44444
82 3RAB GNP 0.02384 0.40408 4.44444
83 4ZU4 4TG 0.005091 0.40255 4.44444
84 5J8O 6GZ 0.007062 0.4191 4.83871
85 4BVA T3 0.0007143 0.49299 5.18518
86 3MF2 AMP 0.0005419 0.48841 5.18518
87 4DE9 VTP 0.0008948 0.47206 5.18518
88 5WL0 21G 0.003377 0.45703 5.18518
89 4OPC FDA 0.004968 0.45467 5.18518
90 4OPC PGT 0.005498 0.45467 5.18518
91 5AMV ADA ADA ADA 0.01006 0.43841 5.18518
92 5A65 TPP 0.001345 0.43201 5.18518
93 3PTQ NFG 0.005003 0.42983 5.18518
94 1VYF OLA 0.005207 0.42958 5.18518
95 3SLS 77D 0.01602 0.4257 5.18518
96 4WW7 AMP 0.007639 0.42407 5.18518
97 1ERB ETR 0.004239 0.41415 5.18518
98 4WN5 MVC 0.0005429 0.48017 5.21739
99 5KEW 6SB 0.001342 0.42934 5.31915
100 4AZT LY2 0.0002703 0.46292 5.92593
101 3PQB VGP 0.001271 0.45711 5.92593
102 2Q0D ATP 0.003295 0.45392 5.92593
103 3FW4 CAQ 0.0009481 0.43329 5.92593
104 2R5V HHH 0.002313 0.4135 5.92593
105 1IIU RTL 0.009863 0.41324 5.92593
106 5H2D ERG 0.01223 0.41152 5.92593
107 3VOT ADP 0.01662 0.40827 5.92593
108 3ILR IXD 0.01115 0.40805 5.92593
109 3ILR SGN 0.01115 0.40805 5.92593
110 4H6Q FAD 0.02718 0.40309 5.92593
111 4H6Q TFB 0.03368 0.40121 5.92593
112 3F5O UOC COA 0.03172 0.40045 5.92593
113 1EWJ BLM 0.01125 0.40111 6.34921
114 3GWL FAD 0.01141 0.41558 6.60377
115 4IGH 1EA 0.0006356 0.50996 6.66667
116 4IGH FMN 0.0006356 0.50996 6.66667
117 4IGH ORO 0.0006356 0.50996 6.66667
118 2Z77 HE7 0.0002344 0.50312 6.66667
119 4KYS VIB 0.0002261 0.4869 6.66667
120 2J3M PRI 0.001912 0.4671 6.66667
121 4D1J DGJ 0.000703 0.4587 6.66667
122 5W0N UPU 0.001525 0.4511 6.66667
123 2J3M ATP 0.002939 0.44733 6.66667
124 3KFF ZBT 0.003574 0.44157 6.66667
125 3KFF XBT 0.003574 0.44157 6.66667
126 4X6F 3XU 0.0073 0.43636 6.66667
127 4RFR RHN 0.002346 0.43608 6.66667
128 3ETH ATP 0.002417 0.42641 6.66667
129 5FQK 6NT 0.006799 0.42611 6.66667
130 3KRR DQX 0.02183 0.41993 6.66667
131 5GXU FAD 0.02941 0.41823 6.66667
132 2A1L PCW 0.01744 0.41671 6.66667
133 1KOR ARG 0.03995 0.41645 6.66667
134 1KOR SIN 0.03995 0.41645 6.66667
135 3X0Y FMN 0.00902 0.41429 6.66667
136 3F5K CE5 0.01812 0.40313 6.66667
137 1KQW RTL 0.0005904 0.48162 6.71642
138 2P7Q GG6 0.006136 0.4212 6.76692
139 5U98 1KX 0.001638 0.46037 7.07071
140 4M1U A2G MBG 0.0004468 0.45548 7.14286
141 5OO5 UUA 0.0004818 0.45399 7.25806
142 3QUZ QUV 0.0007795 0.53558 7.40741
143 2I74 MAN MAN MAN MAN 0.0001055 0.49627 7.40741
144 2CKM AA7 0.01516 0.46838 7.40741
145 5JSP DQY 0.0003866 0.45495 7.40741
146 3FON VAL ASN ASP ILE PHE GLU ALA ILE 0.01051 0.42715 7.40741
147 5KF6 TFB 0.02737 0.41289 7.40741
148 5KF6 FAD 0.02737 0.41289 7.40741
149 3E8T UQ8 0.002052 0.4639 8.14815
150 1ZNY GDP 0.001405 0.43098 8.14815
151 2YG2 S1P 0.004662 0.4307 8.14815
152 3TNF GNP 0.02089 0.41598 8.14815
153 3WYF GTP 0.02559 0.40346 8.14815
154 4MJ0 BGC SIA SIA GAL 0.007144 0.40255 8.14815
155 4MJ0 SIA SIA GAL 0.006704 0.40155 8.14815
156 2QZ3 XYP XYP XYP 0.0004915 0.45074 8.88889
157 5VC5 96M 0.001188 0.44996 8.88889
158 5DQ8 FLF 0.00435 0.43246 8.88889
159 1QZY TDE 0.009196 0.42143 8.88889
160 5CFT 51G 0.01306 0.41919 8.88889
161 2E0P CTT 0.01035 0.4169 8.88889
162 5IXH OTP 0.002631 0.47998 9.62963
163 4OAV ACP 0.002136 0.45748 9.62963
164 5W10 CMP 0.002056 0.4516 9.62963
165 4MNS 2AX 0.002218 0.44555 9.62963
166 3RGA LSB 0.003754 0.42401 9.62963
167 4MUV PCG 0.002546 0.41331 9.62963
168 4O1P ANP 0.007821 0.40751 9.62963
169 1F3D TPM 0.002707 0.40577 9.62963
170 1ZM1 BGC BGC BGC 0.0009289 0.43698 10.3704
171 5UFQ GNP 0.01535 0.42792 10.3704
172 2RDQ AKG 0.006222 0.42777 10.3704
173 1XIM XYL 0.004177 0.42138 10.3704
174 2FCU AKG 0.005224 0.40871 10.3704
175 1UU6 BGC BGC BGC BGC 0.02533 0.4072 10.3704
176 1ODM ASV 0.0002287 0.52646 11.1111
177 5HA0 LTD 0.000849 0.44739 11.1111
178 3B1Q NOS 0.005519 0.42817 11.1111
179 5LJB RTL 0.005023 0.42239 11.1111
180 5JKG 6LF 0.01414 0.42102 11.1111
181 2RG0 CBI 0.0036 0.4125 11.1111
182 3Q8G PEE 0.007036 0.41136 11.1111
183 5JJU AMP 0.01062 0.40743 11.1111
184 3DJV C3P 0.007276 0.4809 11.2903
185 4P8K FAD 0.001024 0.51051 11.8519
186 4P8K 38C 0.001024 0.51051 11.8519
187 1URX AAL GAL AAL GLA 0.001676 0.44466 11.8519
188 4P25 FUC GAL NAG FUC 0.003669 0.40629 11.8519
189 3RI1 3RH 0.01823 0.40375 11.8519
190 3L5R 47X 0.01716 0.43394 12.2951
191 1U0A BGC BGC BGC BGC 0.0000465 0.4979 12.5926
192 1NF3 GNP 0.01664 0.42301 12.5926
193 1ZB6 DIN 0.003525 0.42241 12.5926
194 1ZB6 GST 0.00371 0.42241 12.5926
195 3JU6 ANP 0.002304 0.41731 12.5926
196 5X7Q GLC GLC GLC GLC GLC 0.001302 0.41723 12.5926
197 2NGR GDP 0.01297 0.41183 12.5926
198 5MZI FYK 0.03538 0.40965 12.5926
199 5MZI FAD 0.03466 0.40965 12.5926
200 4DSU BZI 0.001862 0.40152 12.5926
201 1D5Z ACE ALC ARG ALA ODA SER LEU NH2 0.004898 0.45828 13.3333
202 3EKK GS2 0.01064 0.44744 13.3333
203 2XXP DSL 0.013 0.4474 13.3333
204 3B6R ADP 0.004385 0.41466 13.3333
205 2YNE NHW 0.02374 0.40289 13.3333
206 2YNE YNE 0.02374 0.40289 13.3333
207 4NPL AKG 0.0001877 0.48912 14.0741
208 4RYV ZEA 0.0029 0.43119 14.0741
209 3E85 BSU 0.007554 0.4191 14.0741
210 5BU3 4W9 0.004695 0.40394 14.0741
211 4O8A FAD 0.03201 0.40312 14.0741
212 5ENQ 5QE 0.005194 0.45157 14.8148
213 1MH1 GNP 0.02221 0.41033 14.8148
214 2F2L MLD 0.02481 0.4032 14.8148
215 5EPQ OLA 0.0001066 0.49469 15.5556
216 1SQI 869 0.001018 0.44313 15.5556
217 3AGC RCC 0.008083 0.42394 15.5556
218 1YKD CMP 0.003272 0.4219 15.5556
219 3TKL GTP 0.02355 0.40062 15.5556
220 2WKQ GTP 0.01913 0.41048 16.2963
221 3W9R A8S 0.03012 0.40117 16.2963
222 1EM6 CP4 0.007271 0.48469 17.037
223 1N5S ADL 0.0001059 0.52042 17.8571
224 3VV1 GAL FUC 0.000000000008276 0.91187 20
225 3QP8 HL0 0.006301 0.42694 20.7407
226 1KGI T4A 0.001091 0.4519 22.0472
227 1S4M LUM 0.005554 0.41014 22.2222
228 3M3E GAL A2G NPO 0.000000001974 0.74224 25.9259
229 3VQ2 LP4 LP5 MYR DAO 0.001187 0.46986 27.4074
230 1QKQ MAN 0.000000003932 0.7555 29.6296
231 1UMZ BGC BGC XYS BGC XYS GAL 0.00001385 0.55904 33.3333
232 4QJP V1F 0.006287 0.41253 35.5556
233 4HDQ GNP 0.01604 0.41633 42.3077
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