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Receptor
PDB id Resolution Class Description Source Keywords
5DWQ 2.36 Å EC: 2.1.1.125 CRYSTAL STRUCTURE OF CARM1, SINEFUNGIN, AND METHYLATED H3 PE (R17) HOMO SAPIENS PROTEIN-SUBSTRATE TERNARY COMPLEX TRANSFERASE
Ref.: STRUCTURAL INSIGHTS INTO TERNARY COMPLEX FORMATION CARM1 WITH VARIOUS SUBSTRATES. ACS CHEM.BIOL. V. 11 763 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL A:502;
C:502;
C:503;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
SFG D:501;
A:501;
C:501;
B:501;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
381.387 C15 H23 N7 O5 c1nc(...
SO4 D:502;
B:502;
Invalid;
Invalid;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5DWQ 2.36 Å EC: 2.1.1.125 CRYSTAL STRUCTURE OF CARM1, SINEFUNGIN, AND METHYLATED H3 PE (R17) HOMO SAPIENS PROTEIN-SUBSTRATE TERNARY COMPLEX TRANSFERASE
Ref.: STRUCTURAL INSIGHTS INTO TERNARY COMPLEX FORMATION CARM1 WITH VARIOUS SUBSTRATES. ACS CHEM.BIOL. V. 11 763 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 5DWQ - SFG C15 H23 N7 O5 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 5DWQ - SFG C15 H23 N7 O5 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 5DWQ - SFG C15 H23 N7 O5 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SFG; Similar ligands found: 231
No: Ligand ECFP6 Tc MDL keys Tc
1 SFG 1 1
2 0UM 0.689655 0.887324
3 SAI 0.654762 0.940298
4 SA8 0.642857 0.9
5 SAH 0.635294 0.954545
6 EEM 0.62069 0.875
7 5X8 0.619048 0.924242
8 S7M 0.606742 0.875
9 ADN 0.597222 0.850746
10 RAB 0.597222 0.850746
11 XYA 0.597222 0.850746
12 5CD 0.594595 0.863636
13 5N5 0.581081 0.850746
14 62X 0.574468 0.84
15 A4D 0.573333 0.850746
16 K15 0.568421 0.863014
17 DTA 0.564103 0.84058
18 6RE 0.560976 0.833333
19 SAM 0.555556 0.875
20 EP4 0.551282 0.802817
21 KB1 0.55102 0.887324
22 M2T 0.544304 0.780822
23 SMM 0.537634 0.84
24 MTA 0.5375 0.826087
25 AMP 0.53012 0.77027
26 A 0.53012 0.77027
27 ZAS 0.53012 0.816901
28 LMS 0.53012 0.678571
29 J7C 0.529412 0.84507
30 3DH 0.52439 0.826087
31 GJV 0.523256 0.821918
32 SON 0.522727 0.813333
33 0XU 0.522222 0.938462
34 SRP 0.521277 0.813333
35 SSA 0.521277 0.697674
36 AOC 0.517647 0.826087
37 CA0 0.516854 0.776316
38 5AL 0.516129 0.786667
39 DSZ 0.515464 0.717647
40 AMO 0.515464 0.813333
41 GSU 0.515152 0.738095
42 KH3 0.514286 0.851351
43 ABM 0.511628 0.75
44 A2D 0.511628 0.75
45 A3N 0.511628 0.814286
46 A5A 0.510638 0.682353
47 5CA 0.510417 0.697674
48 SRA 0.505882 0.730769
49 S4M 0.505747 0.792208
50 A3S 0.505618 0.895522
51 A7D 0.505618 0.882353
52 AN2 0.505618 0.74026
53 GAP 0.505376 0.776316
54 54H 0.5 0.666667
55 M33 0.5 0.74026
56 LAD 0.5 0.818182
57 A12 0.5 0.766234
58 ADX 0.5 0.678571
59 Y3J 0.5 0.80303
60 DSH 0.5 0.871429
61 LSS 0.5 0.681818
62 KAA 0.5 0.712644
63 VMS 0.5 0.666667
64 AP2 0.5 0.766234
65 BA3 0.5 0.75
66 SXZ 0.49505 0.875
67 ME8 0.49505 0.775
68 AHX 0.494949 0.759494
69 53H 0.494845 0.659091
70 DAL AMP 0.494845 0.786667
71 TSB 0.494845 0.674419
72 G5A 0.494624 0.697674
73 50T 0.494505 0.74026
74 ADP 0.494382 0.75
75 5AS 0.494382 0.640449
76 AP5 0.494382 0.75
77 B4P 0.494382 0.75
78 F0P 0.490909 0.9
79 GEK 0.489796 0.913043
80 8QN 0.489796 0.786667
81 AT4 0.488889 0.721519
82 5AD 0.486842 0.828125
83 PAJ 0.484848 0.728395
84 52H 0.484536 0.659091
85 AU1 0.483516 0.730769
86 MAO 0.483146 0.782051
87 A3G 0.482759 0.882353
88 NEC 0.482759 0.797101
89 3AM 0.482353 0.733333
90 YAP 0.480769 0.802632
91 7D7 0.480519 0.794118
92 NB8 0.480392 0.782051
93 TXA 0.480392 0.766234
94 NVA LMS 0.48 0.693182
95 ATF 0.479167 0.721519
96 HEJ 0.478261 0.75
97 A3T 0.478261 0.852941
98 ACP 0.478261 0.753247
99 ATP 0.478261 0.75
100 7MD 0.476636 0.775
101 YSA 0.47619 0.697674
102 XAH 0.47619 0.775
103 9ZA 0.474747 0.746835
104 9ZD 0.474747 0.746835
105 APR 0.473118 0.773333
106 5FA 0.473118 0.75
107 AR6 0.473118 0.773333
108 AQP 0.473118 0.75
109 PRX 0.473118 0.753247
110 APC 0.473118 0.766234
111 WAQ 0.470588 0.815789
112 4AD 0.47 0.802632
113 NSS 0.47 0.697674
114 F2R 0.469565 0.756098
115 A5D 0.468085 0.84058
116 RBY 0.468085 0.789474
117 ADV 0.468085 0.789474
118 AD9 0.468085 0.730769
119 AGS 0.468085 0.7125
120 SAP 0.468085 0.7125
121 ADP PO3 0.468085 0.77027
122 MHZ 0.467391 0.782051
123 FA5 0.466667 0.813333
124 PTJ 0.466019 0.7375
125 00A 0.465347 0.746835
126 8X1 0.464646 0.693182
127 D3Y 0.464646 0.869565
128 VRT 0.463158 0.871429
129 GA7 0.462963 0.74359
130 LEU LMS 0.460784 0.674157
131 S8M 0.46 0.859155
132 OOB 0.46 0.786667
133 ADP VO4 0.459184 0.74026
134 VO4 ADP 0.459184 0.74026
135 T99 0.458333 0.721519
136 ANP 0.458333 0.730769
137 TAT 0.458333 0.721519
138 ACQ 0.458333 0.753247
139 B5V 0.456311 0.766234
140 AAT 0.453608 0.847222
141 2AM 0.453488 0.723684
142 8PZ 0.45283 0.697674
143 FYA 0.451923 0.786667
144 YLC 0.451327 0.797468
145 DLL 0.45098 0.786667
146 A3P 0.450549 0.746667
147 YLP 0.45045 0.777778
148 A22 0.45 0.74026
149 ARG AMP 0.449541 0.765432
150 ADP ALF 0.44898 0.7125
151 ALF ADP 0.44898 0.7125
152 2VA 0.446809 0.828571
153 OAD 0.446602 0.776316
154 3UK 0.446602 0.776316
155 80F 0.445378 0.73494
156 TYR AMP 0.444444 0.802632
157 6YZ 0.444444 0.753247
158 IOT 0.443478 0.768293
159 9SN 0.443396 0.7375
160 PR8 0.442308 0.807692
161 P5A 0.442308 0.704545
162 7D5 0.44186 0.714286
163 A1R 0.441176 0.769231
164 7C5 0.440367 0.797297
165 TT8 0.44 0.926471
166 YLA 0.439655 0.777778
167 YLB 0.438596 0.777778
168 3OD 0.438095 0.776316
169 9K8 0.438095 0.655556
170 BIS 0.438095 0.725
171 1ZZ 0.438095 0.753086
172 NVA 2AD 0.4375 0.859155
173 MAP 0.435644 0.7125
174 MYR AMP 0.433962 0.753086
175 NAI 0.433628 0.725
176 SO8 0.43299 0.816901
177 9X8 0.432692 0.734177
178 A6D 0.432692 0.74359
179 25A 0.431373 0.75
180 5SV 0.431373 0.7375
181 TYM 0.429825 0.813333
182 WSA 0.429825 0.705882
183 LAQ 0.428571 0.753086
184 3NZ 0.428571 0.833333
185 A3R 0.427184 0.769231
186 ADQ 0.427184 0.753247
187 8Q2 0.426087 0.674157
188 7MC 0.426087 0.756098
189 B5Y 0.425926 0.75641
190 B5M 0.425926 0.75641
191 LPA AMP 0.424779 0.753086
192 48N 0.424779 0.759494
193 JB6 0.424528 0.746835
194 PPS 0.424242 0.658824
195 AYB 0.423729 0.768293
196 PAP 0.42268 0.736842
197 OVE 0.422222 0.696203
198 3AD 0.421687 0.863636
199 4YB 0.419643 0.72093
200 A2P 0.419355 0.733333
201 CMP 0.419355 0.753425
202 2BA 0.419355 0.743243
203 ADP BMA 0.419048 0.753247
204 4UV 0.418182 0.75641
205 AHZ 0.415929 0.731707
206 QQX 0.41573 0.670886
207 A A 0.415094 0.75
208 AP0 0.413793 0.695122
209 ATP A A A 0.412844 0.76
210 SP1 0.411111 0.705128
211 QQY 0.411111 0.679487
212 ACK 0.411111 0.716216
213 RP1 0.411111 0.705128
214 AFH 0.410714 0.728395
215 4UU 0.410714 0.75641
216 DND 0.408696 0.766234
217 NXX 0.408696 0.766234
218 TXD 0.408696 0.725
219 7D3 0.408602 0.696203
220 CC5 0.407407 0.876923
221 25L 0.407407 0.74026
222 TAD 0.40708 0.75
223 DQV 0.40708 0.763158
224 AMP DBH 0.405405 0.753247
225 TXE 0.405172 0.725
226 AF3 ADP 3PG 0.405172 0.75
227 OMR 0.405172 0.743902
228 MTP 0.404762 0.72973
229 N0B 0.401575 0.777778
230 V3L 0.4 0.773333
231 YLY 0.4 0.768293
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5DWQ; Ligand: SFG; Similar sites found with APoc: 678
This union binding pocket(no: 1) in the query (biounit: 5dwq.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 5CLO NS8 None
2 4PIO AVI 1.23839
3 4PIO SAH 1.23839
4 6C8R EQV 1.43266
5 4ONQ SFG 1.43266
6 6C8R SAH 1.43266
7 5BVA FAD 1.43266
8 5N0J FAD 1.43266
9 5GSN NAP 1.43266
10 5GSN FAD 1.43266
11 5GSN MMZ 1.43266
12 3T31 DCQ 1.43266
13 3GMB FAD 1.43266
14 5HXI 5HN 1.43266
15 3GEG NAD 1.61943
16 4YAC NAI 1.6835
17 3LCC SAH 1.70213
18 1GPE FAD 1.7192
19 3L9W AMP 1.7192
20 3NYC IAR 1.7192
21 3NYC FAD 1.7192
22 1FEC FAD 1.7192
23 3L9W GSH 1.7192
24 4EIP FAD 1.7192
25 2VVM FAD 1.7192
26 5KOX FAD 1.7192
27 5KOX RFP 1.7192
28 4RD0 GDP 1.7192
29 2VVL FAD 1.7192
30 3K7M FAD 1.7192
31 6DEN TP9 1.7192
32 6DEN G8A 1.7192
33 6DEN FAD 1.7192
34 5UIJ TYD 1.7192
35 6AYU F6P 1.72911
36 3QPB URA 1.77305
37 5EB3 UEG 1.88679
38 4ZRN UPG 1.92308
39 4ZRN NAD 1.92308
40 4UCI SAM 2.00573
41 3HDY FAD 2.00573
42 3HDY GDU 2.00573
43 3HDY FDA 2.00573
44 6F7L FAD 2.00573
45 5G48 1FL 2.00573
46 1I8T FAD 2.00573
47 3CGD FAD 2.00573
48 3CGD COA 2.00573
49 5X68 FAD 2.00573
50 4TM3 FAD 2.00573
51 3CGB FAD 2.00573
52 3CGD NAD 2.00573
53 2JB2 PHE 2.00573
54 2JB2 FAD 2.00573
55 5NG7 SER 2.00669
56 3QJ4 FAD 2.04678
57 1UAY ADN 2.06612
58 3FPZ AHZ 2.14724
59 1XG5 NAP 2.15054
60 2Q7V FAD 2.15385
61 3F8D FAD 2.16718
62 3VYW SAM 2.27273
63 4RVG TYD 2.29226
64 4RVG SAM 2.29226
65 4D7E FAD 2.29226
66 4D04 FAD 2.29226
67 4D04 NAP 2.29226
68 4TXI FAD 2.29226
69 2Q1S NAI 2.29226
70 1SQF SAM 2.29226
71 5ICE 2H4 2.29226
72 5ICE SAH 2.29226
73 6H3O FAD 2.29226
74 1RYI FAD 2.29226
75 2Q28 ADP 2.29226
76 4UBS DIF 2.29226
77 4U8P UDP 2.29226
78 4U8P FDA 2.29226
79 1E1M NAP 2.29226
80 1E1M FAD 2.29226
81 1RYI GOA 2.29226
82 1X87 NAD 2.29226
83 3LU1 NAD 2.29226
84 2WPB ZZI 2.30263
85 4JNA FAD 2.35294
86 1R6D NAD 2.37389
87 1R6D DAU 2.37389
88 3O7W SAM 2.38095
89 4ZCC FAD 2.38095
90 4ZCC NAI 2.38095
91 4NTC FAD 2.38806
92 3LCV SAM 2.4911
93 1DL5 SAH 2.52366
94 3VC1 GST 2.5641
95 3VC1 SAH 2.5641
96 2CDU ADP 2.5788
97 2RGO FAD 2.5788
98 6FP4 FAD 2.5788
99 6FP4 E1T 2.5788
100 6ER9 NAP 2.5788
101 1UWK URO 2.5788
102 1UWK NAD 2.5788
103 1H82 GZZ 2.5788
104 1H82 FAD 2.5788
105 2CDU FAD 2.5788
106 2RGH FAD 2.5788
107 4EMI NAD 2.5788
108 4EMI FAD 2.5788
109 3G5S FAD 2.5788
110 2JHP SAH 2.5788
111 1PS9 FAD 2.5788
112 2B9W FAD 2.5788
113 3CBG SAH 2.58621
114 4ZJS 4P0 2.6087
115 1RJW ETF 2.65487
116 1N2X SAM 2.65781
117 1JQ3 AAT 2.7027
118 2Q1W NAD 2.7027
119 3I53 SAH 2.71084
120 6BQ6 TER 2.71903
121 3SQP FAD 2.71967
122 1JQD SAH 2.73973
123 2AOT SAH 2.73973
124 1JQD HSM 2.73973
125 6BWL NAD 2.7439
126 3WV8 ATP 2.75229
127 2OBF F83 2.76817
128 2OBF SAH 2.76817
129 1L1E SAH 2.78746
130 3GU3 SAH 2.8169
131 3LAD FAD 2.86533
132 3X0V FAD 2.86533
133 5I39 FAD 2.86533
134 4J36 FAD 2.86533
135 4J36 1HR 2.86533
136 4A6D SAM 2.86533
137 4REP FAD 2.86533
138 5VN0 FAD 2.86533
139 5VN0 NAI 2.86533
140 2JJQ SAH 2.86533
141 3LXD FAD 2.86533
142 3ICT ADP 2.86533
143 3ICR FAD 2.86533
144 3ICS FAD 2.86533
145 3ICT FAD 2.86533
146 1PN0 FAD 2.86533
147 3ICS ADP 2.86533
148 1PN0 IPH 2.86533
149 5TTJ FAD 2.86533
150 4C3Y FAD 2.86533
151 5Y77 FAD 2.86533
152 6AIN FAD 2.86533
153 5XNC MTA 2.86533
154 2XVF FAD 2.86533
155 2XVE FAD 2.86533
156 4UP3 FAD 2.86624
157 3TKA SAM 2.88184
158 5AHO TLA 2.97619
159 4NEC SAH 3.0303
160 1E6E FAD 3.125
161 4AZW SAM 3.15186
162 5YF1 SFG 3.15186
163 5YF1 8V0 3.15186
164 5U8U FAD 3.15186
165 4JDR FAD 3.15186
166 5ERG SAM 3.15186
167 3AB1 FAD 3.15186
168 5EZ7 FAD 3.15186
169 4HXY NDP 3.15186
170 5KMS NAD 3.15186
171 3K6V CIT 3.15186
172 1RP0 AHZ 3.16901
173 3DXY SAM 3.21101
174 3G89 SAM 3.21285
175 3LTW HLZ 3.21429
176 6FDF SAH 3.29341
177 1RRC ADP 3.32226
178 3HAV SRY 3.34448
179 3FPF TNA 3.3557
180 3FPF MTA 3.3557
181 2CBZ ATP 3.37553
182 3LKZ SFG 3.42679
183 5LOG SAH 3.43348
184 4AP3 FAD 3.4384
185 4AP3 NAP 3.4384
186 5KOK SAH 3.4384
187 5KOK S9T 3.4384
188 4MO2 FDA 3.4384
189 4MO2 FAD 3.4384
190 5KOK R9T 3.4384
191 2ZWA SAH 3.4384
192 3QFA FAD 3.4384
193 2DKH 3HB 3.4384
194 2DKH FAD 3.4384
195 4K5S PM0 3.4384
196 4K5S FAD 3.4384
197 4RF7 ARG 3.4384
198 4CNK FAD 3.4384
199 5MZI FYK 3.4384
200 5MZI FAD 3.4384
201 1Q1R FAD 3.4384
202 2A8X FAD 3.4384
203 1SB8 UD2 3.4384
204 1SB8 NAD 3.4384
205 3OZ2 FAD 3.4384
206 4EUE NAI 3.4384
207 2YVJ NAI 3.4384
208 2YVF FAD 3.4384
209 2YVF NAD 3.4384
210 5THQ NDP 3.4384
211 3CH6 NAP 3.4965
212 3CH6 311 3.4965
213 4OBW SAM 3.50195
214 1MFI FHC 3.50877
215 5U19 827 3.51906
216 5U19 SAH 3.51906
217 4Z2S NDG 3.52113
218 4Z2S NAG 3.52113
219 2OFD NGA 3.52113
220 2OFE NAG 3.52113
221 5W7K SAH 3.52564
222 2I7C AAT 3.53357
223 5N5D SAM 3.53982
224 3FRH SAH 3.55731
225 3MAG SAH 3.58306
226 5N53 8NB 3.58974
227 5BSZ SAH 3.6
228 1BDB NAD 3.61011
229 2O07 SPD 3.61842
230 2O07 MTA 3.61842
231 2VDV SAM 3.65854
232 3OU2 SAH 3.66972
233 3MCT SAH 3.7037
234 2ZFU SAH 3.72093
235 3SSO SAH 3.72493
236 3AXB PRO 3.72493
237 3AXB FAD 3.72493
238 4M52 FAD 3.72493
239 6GAR FAD 3.72493
240 1RSG FAD 3.72493
241 3KLJ FAD 3.72493
242 1YY5 FAD 3.72493
243 3VSE SAH 3.72493
244 4M52 M52 3.72493
245 5JAQ NAI 3.72493
246 5F2K SAH 3.72493
247 5F2K OCA 3.72493
248 1FUR MLT 3.72493
249 2NPX FAD 3.72493
250 1WVG APR 3.72493
251 2NPX NAD 3.72493
252 1NW5 SAM 3.76176
253 4NTD FAD 3.82353
254 5W7M SAH 3.84615
255 1GVF PGH 3.84615
256 4XZ3 ACP 3.91304
257 5KVA SAM 3.95683
258 4POO SAM 4
259 3P2E SAH 4
260 4MOP 2H5 4.01146
261 3NKS FAD 4.01146
262 3Q9T FAY 4.01146
263 1VHZ APR 4.0404
264 2PT9 2MH 4.04984
265 2PT9 S4M 4.04984
266 5TWB FAD 4.06977
267 6ECU SAH 4.11392
268 2VGD XYP XYP 4.12844
269 3JWH SAH 4.14747
270 2HQM FAD 4.17537
271 1V59 FAD 4.1841
272 1V59 NAD 4.1841
273 4CQM NAP 4.21456
274 3LZW NAP 4.21687
275 3LZW FAD 4.21687
276 3C3Y SAH 4.21941
277 5YJI 8WO 4.22535
278 5YJI SAH 4.22535
279 6GAS FAD 4.22961
280 5MGZ SAH 4.23729
281 2PZM NAD 4.24242
282 2PZM UDP 4.24242
283 5XLX SAH 4.25532
284 1LSS NAD 4.28571
285 3C6K MTA 4.29799
286 3C6K SPD 4.29799
287 3UOY FAD 4.29799
288 3UOY NAP 4.29799
289 2Z3Y F2N 4.29799
290 1QO8 FAD 4.29799
291 3P9C SAH 4.29799
292 3S5W FAD 4.29799
293 6D6Y SAH 4.29799
294 2PNC CLU 4.29799
295 1X14 NAD 4.29799
296 2BZG SAH 4.31034
297 5M58 SAH 4.34783
298 3SAO DBH 4.375
299 1R18 SAH 4.40529
300 4GLL NAD 4.45104
301 3MA0 XYP 4.47284
302 5FJN BE2 4.58453
303 5FJN FAD 4.58453
304 1LVL FAD 4.58453
305 1ZK7 FAD 4.58453
306 2BRY FAD 4.58453
307 5EB4 FAD 4.58453
308 4B63 ORN 4.58453
309 4B63 NAP 4.58453
310 4B63 FAD 4.58453
311 5YB7 ORN 4.58453
312 5YB7 FAD 4.58453
313 5G3U FDA 4.58453
314 5G3U ITW 4.58453
315 1LVL NAD 4.58453
316 3WMX NAD 4.58453
317 4BJZ FAD 4.58453
318 4BJZ P3A 4.58453
319 4FZV SAM 4.60251
320 1G60 SAM 4.61538
321 3ZV6 4HB 4.62633
322 3ZV6 NAD 4.62633
323 1HSR BHO 4.65116
324 3SJU NDP 4.6595
325 1GZ6 NAI 4.70219
326 3ITJ FAD 4.73373
327 3ITJ CIT 4.73373
328 4II2 ATP 4.81928
329 2PX8 SAH 4.83271
330 5K0A FAD 4.84848
331 4KRI SAH 4.87106
332 1KYZ SAH 4.87106
333 2IID PHE 4.87106
334 2IID FAD 4.87106
335 1COY FAD 4.87106
336 5DNK SAH 4.87106
337 3TKY SAH 4.87106
338 4USR FAD 4.87106
339 1COY AND 4.87106
340 3E1T FAD 4.87106
341 1KYZ FER 4.87106
342 1ZBQ NAD 4.89297
343 3FXU TSU 4.91803
344 2WK1 SAH 4.96454
345 5ME4 HP4 5.10949
346 3S1S SAH 5.15759
347 3PT9 SAH 5.15759
348 3GD4 NAD 5.15759
349 3GD4 FAD 5.15759
350 5F8F SFG 5.15759
351 1REO FAD 5.15759
352 5BJX NAD 5.15759
353 5BJX UDP 5.15759
354 2RGJ FAD 5.15759
355 2IZ1 ATR 5.15759
356 1OC2 TDX 5.17241
357 1OC2 NAD 5.17241
358 1Y8Q ATP 5.20231
359 5ZZ6 ADP 5.28846
360 3BGD SAH 5.38462
361 3BGD PM6 5.38462
362 1RJD SAM 5.38922
363 3DMH GMP 5.44413
364 3DMH SAM 5.44413
365 4Z24 FAD 5.44413
366 2R4J FAD 5.44413
367 2R4J 13P 5.44413
368 2RAB NAD 5.44413
369 2RAB FAD 5.44413
370 1NAA 6FA 5.44413
371 1NAA ABL 5.44413
372 5MBX FAD 5.44413
373 5MBX SP5 5.44413
374 4E70 N7I 5.44413
375 5FTW SAH 5.46875
376 2UYQ SAM 5.48387
377 4BLW AMP 5.53633
378 4BLW SAH 5.53633
379 2HMT NAI 5.55556
380 2P41 SAH 5.57377
381 4EMJ FAD 5.60748
382 1NJR XYL 5.6338
383 5YJF SAH 5.6338
384 5YJF 8WO 5.6338
385 4IWN GEK 5.67686
386 1PJS NAD 5.73066
387 1FP2 SAH 5.73066
388 1Q9I TEO 5.73066
389 1Q9I FAD 5.73066
390 5JCM NAD 5.73066
391 5JCM ISD 5.73066
392 5JCM FAD 5.73066
393 1FP2 HMO 5.73066
394 2AWN ADP 5.73066
395 1I1N SAH 5.75221
396 3A4T SFG 5.83942
397 5TUF FAD 5.86797
398 5TUF TDC 5.86797
399 3A25 SAM 5.98007
400 3FZG SAM 6
401 4HA6 FAD 6.01719
402 2IVD FAD 6.01719
403 4LOC BTN 6.01719
404 3LST SAH 6.03448
405 4KXQ APR 6.04982
406 2ZIF SAM 6.06061
407 1I9G SAM 6.07143
408 2Q0L FAD 6.10932
409 5MIT FAD 6.11621
410 5MIT NAP 6.11621
411 1Q0S SAH 6.17761
412 3EVG SAH 6.18182
413 2FJK 13P 6.22951
414 1U2Z SAH 6.30372
415 1BZL GCG 6.30372
416 2YG3 FAD 6.30372
417 1BZL FAD 6.30372
418 3UCL CYH 6.30372
419 3UCL NAP 6.30372
420 3UCL FAD 6.30372
421 5O42 9JW 6.30372
422 5O42 BGC 6.30372
423 5O42 NAD 6.30372
424 4ITU 1HS 6.3197
425 4ITU NAI 6.3197
426 5E72 SAM 6.35838
427 5E9W SAH 6.41026
428 4KIB SAH 6.59026
429 3QOX SAH 6.59026
430 3RNM FAD 6.59026
431 5J5Z FAD 6.59026
432 1ELI PYC 6.59026
433 2VL1 GLY GLY 6.59026
434 2QA1 FAD 6.59026
435 4RSL FAD 6.59026
436 3ZNN 4WL 6.62824
437 3ZNN FAD 6.62824
438 6ECW SAH 6.66667
439 1JNR FAD 6.66667
440 6GNO XDI 6.66667
441 2WSB NAD 6.69291
442 1VBO MAN MAN MAN 6.71141
443 3HVJ 705 6.78733
444 4TQG NDP 6.81115
445 4DMG SAM 6.87023
446 3GDN FAD 6.87679
447 3GDN HBX 6.87679
448 5W7R SAH 6.87679
449 3NTD FAD 6.87679
450 3NTA FAD 6.87679
451 5MW4 5JU 6.88623
452 4X7Y SAH 6.93431
453 1QAN SAH 6.96721
454 3ELW SAM 7
455 3ELW GP3 7
456 3Q87 SAM 7.05882
457 5ULP KB1 7.08955
458 5UFN SAH 7.14286
459 6F97 FAD 7.16332
460 3IHG FAD 7.16332
461 5WGR FAD 7.16332
462 4J56 FAD 7.16332
463 5K7U SAM 7.16332
464 2AQJ FAD 7.16332
465 2AQJ TRP 7.16332
466 3EVF SAH 7.22022
467 3EVF GTA 7.22022
468 3NUG NAD 7.28745
469 4BV6 FAD 7.44986
470 1YQZ FAD 7.44986
471 1RKX NAD 7.44986
472 2J5V RGP 7.44986
473 1XSE NDP 7.45763
474 5E1M SAH 7.46888
475 5E1M PRO PRO LYS ARG ILE ALA 7.46888
476 5DLY 5D7 7.5188
477 5DLY SAH 7.5188
478 4YUW 4JU 7.56579
479 4YUW S4M 7.56579
480 6DUB SAH 7.65766
481 1MID LAP 7.69231
482 5HJM MTA 7.73639
483 2EJU SAH 7.73639
484 2WPF FAD 7.73639
485 2WPF WPF 7.73639
486 1FP1 SAH 7.73639
487 6GN6 MAL 7.73639
488 1EJ0 SAM 7.77778
489 4GK9 MAN BMA MAN MAN MAN 7.8853
490 5THY SAH 7.90123
491 3PFG SAM 7.98479
492 3PFG TLO 7.98479
493 4RDH AMP 7.98611
494 4RDI ATP 7.98611
495 5X62 SAH 8.02292
496 5TS5 FAD 8.02292
497 5GWX SAM 8.09859
498 5GWX SAR 8.09859
499 5THZ SAH 8.14815
500 4YNU FAD 8.30946
501 4YNU LGC 8.30946
502 4USQ FAD 8.30946
503 4MIG G3F 8.30946
504 4D79 ATP 8.33333
505 2VT3 ATP 8.37209
506 3AD8 NAD 8.37438
507 3AD8 FAD 8.37438
508 3AD8 PYC 8.37438
509 1KYQ NAD 8.39416
510 1UDB UFG 8.57988
511 1UDB NAD 8.57988
512 5WP5 SAH 8.59599
513 1MO9 KPC 8.59599
514 1MO9 FAD 8.59599
515 1XHC FAD 8.59599
516 3MQ2 SAH 8.7156
517 2GN4 NDP 8.72093
518 2GN4 UD1 8.72093
519 1G55 SAH 8.74636
520 5J60 FAD 8.75
521 1E3W NAD 8.81226
522 3IWD M2T 8.82353
523 1E6W NAD 8.84615
524 6GKV SAH 8.88252
525 5BRT FAD 8.88252
526 5BRT CH9 8.88252
527 1KNR FAD 8.88252
528 1IM8 SAI 9.01639
529 2A14 SAH 9.12547
530 5WP4 SAH 9.16905
531 1D4D FAD 9.16905
532 5MPT SAH 9.16905
533 2GV8 FAD 9.16905
534 4XQC 13D 9.16905
535 1VQW FAD 9.16905
536 2GVC FAD 9.16905
537 4XQC NAD 9.16905
538 5JE0 SAH 9.31174
539 5JE0 AZ8 9.31174
540 5JGL SAM 9.34256
541 2F5Z FAD 9.375
542 3M6W SAM 9.45559
543 3GWZ SAH 9.45559
544 3GXO SAH 9.45559
545 3H8V ATP 9.45559
546 4G5H NAP 9.45559
547 4G5H UD7 9.45559
548 2GMH FAD 9.45559
549 6FHO FAD 9.45559
550 1S7G APR 9.48617
551 1U7T TDT 9.57854
552 4PNE SAH 9.60265
553 6ECT SAM 9.65732
554 5DM1 5D7 9.73783
555 5DM1 SAH 9.73783
556 4Y9D NAI 9.83607
557 5ZHO A2G GLA FUC 9.87654
558 5JJR SAH 10.0287
559 2FK8 SAM 10.0629
560 2P3V SRT 10.1562
561 3OFK SAH 10.1852
562 3FUU ADN 10.3321
563 5TVF CGQ 10.5882
564 1ZGA SAH 10.6443
565 2FKA BEF 10.8527
566 1ZQ9 SAM 10.8772
567 2NXE SAM 11.0236
568 2YX1 SFG 11.3095
569 1KPG SAH 11.4983
570 3TLJ SAH 12.0344
571 5DQY BEZ 12.381
572 2PXX SAH 12.5581
573 4N49 SAM 12.6074
574 1XDS SAM 12.6074
575 2WA2 SAM 12.6812
576 1JG3 ADN 12.766
577 1GET FAD 12.894
578 1GET NAP 12.894
579 5CUQ NSC 13.1086
580 2GAG NAD 13.1313
581 2GAG FAD 13.1313
582 2GAG FOA 13.1313
583 5OC1 FAD 13.1805
584 3CTY FAD 13.1805
585 1QZZ SAM 13.467
586 1NV8 SAM 13.7324
587 1NV8 MEQ 13.7324
588 4RPL FAD 13.7536
589 4RPL 3UC 13.7536
590 4IV9 FAD 13.7536
591 3DUW SAH 13.9013
592 5ZW3 SAH 14.2222
593 6B92 SAH 14.2857
594 5X7Q GLC GLC GLC GLC 14.3266
595 5X7Q GLC GLC GLC 14.3266
596 2XYQ SAH 14.4828
597 4YRY FAD 14.4928
598 4YRY NAD 14.4928
599 4DCM SAM 14.6132
600 4QTU SAM 14.8148
601 4M73 SAH 14.8368
602 4M73 M72 14.8368
603 3U4C NDP 14.9466
604 1TPY SAH 14.9826
605 1OFZ FUL 15
606 1OFZ FUC 15
607 2HNK SAH 15.0628
608 3A27 SAM 15.0735
609 4KRG SAH 15.1862
610 3H2B SAH 15.2709
611 3GDH SAH 15.3527
612 5EEH P9P 15.4255
613 5EEH SAH 15.4255
614 5GM1 SAH 15.8249
615 1XTP SAI 16.1417
616 6GFK SAH 16.7331
617 3MB5 SAM 16.8627
618 1Z3C SA8 17.1141
619 3BXO SAM 17.1548
620 2DPM SAM 17.2535
621 2XVM SAH 17.5879
622 5JCA FAD 17.6056
623 5JCA NDP 17.6056
624 3EGI ADP 17.9612
625 1KPH SAH 18.4669
626 6C5B SAH 18.4751
627 4XUC SAM 18.8073
628 4XUC 43G 18.8073
629 2EWM NAD 18.8755
630 2PWY SAH 19.3798
631 4FC7 COA 19.4946
632 4FC7 NAP 19.4946
633 1XCL SAH 19.5745
634 3X0D SAH 19.7708
635 4X60 SFG 19.7708
636 4X60 3XV 19.7708
637 3NDJ JHZ 19.7708
638 3NDJ SAH 19.7708
639 3T7S SAM 19.7761
640 5BW4 SAM 20
641 1WY7 SAH 20.7729
642 5T67 JHZ 20.9169
643 5T67 SAH 20.9169
644 4R6W PC 20.9302
645 4R6W SAH 20.9302
646 5FA8 SAM 21.118
647 4C4A SAH 21.2034
648 5L95 AMP 21.25
649 1VE3 SAM 21.5859
650 1P1C SAH 23.1156
651 4YMH SAH 25
652 5E8J SAH 25
653 6F5Z SAH 25.974
654 1L3I SAH 26.0417
655 3GCZ SAM 30
656 2EFJ SAH 30
657 5HSA FAS 30
658 1YXM ADE 30
659 4X9M FAD 30
660 2EG5 SAH 30
661 5BUK FAD 30
662 5YEC ATP 33.6134
663 3GRU AMP 35
664 1WG8 SAM 35
665 1GY8 NAD 35
666 4FWE FAD 35
667 4GUT FAD 35
668 4XFR CIT 35
669 4M37 SAH 35.5685
670 4M38 SAH 35.5685
671 3QVP FAD 40
672 4GUS FAD 40
673 5ODQ FAD 40
674 1IY8 NAD 40
675 3G2O SAM 45
676 4LWP SAH 45.8453
677 4Y30 SAH 48.1375
678 4Y30 49L 48.1375
Pocket No.: 2; Query (leader) PDB : 5DWQ; Ligand: SFG; Similar sites found with APoc: 74
This union binding pocket(no: 2) in the query (biounit: 5dwq.bio1) has 24 residues
No: Leader PDB Ligand Sequence Similarity
1 1P6O HPY None
2 2OG2 MLI 1.43266
3 5HXI FAD 1.43266
4 4YMZ 13P 1.59363
5 2PK3 A2R 1.86916
6 2GDZ NAD 1.87266
7 1ZEM NAD 1.9084
8 2C31 TZD 2.29226
9 2C31 ADP 2.29226
10 1RLZ NAD 2.29226
11 2E5V FAD 2.29226
12 4D5G FAD 2.29226
13 3SZB I1E 2.29226
14 4D5G TPP 2.29226
15 1ORR NAD 2.30548
16 3OID NDP 2.32558
17 3SJ7 NDP 2.38095
18 1BXK NAD 2.5788
19 1T9D FAD 2.5788
20 5WKC FAD 2.5788
21 2V57 PRL 2.63158
22 5Y1G AKB 2.7439
23 5Y1G NAD 2.7439
24 4C3Y ANB 2.86533
25 1XHL NDP 2.86533
26 5GWT SIN 2.8777
27 5GWT NAD 2.8777
28 2Q46 NAP 3.16206
29 2EXX NAP 3.26797
30 1OYF MHN 3.30579
31 2YVJ FAD 3.4384
32 5Z75 NAD 3.4384
33 5EJ2 NAD 3.57143
34 3N9R TD3 3.58306
35 3D3W NAP 3.68852
36 1PR9 NAP 3.68852
37 4YAG NAI 3.80623
38 2YY7 NAD 3.84615
39 1GEG NAD 3.90625
40 1I2B UPG 4.01146
41 1I2B NAD 4.01146
42 1I2B USQ 4.01146
43 4OKE AMP 4.16667
44 2DTX BMA 4.54545
45 5FUI APY 4.58453
46 1BC5 SAH 4.83271
47 5NMX FAD 4.87106
48 5NMX NAP 4.87106
49 2BD0 NAP 4.91803
50 4FN4 NAD 5.11811
51 2YGM GLA NAG GAL FUC 5.44413
52 3WGT FAD 6.34006
53 6BYF CIT 7.05882
54 1G0N PHH 7.06714
55 1G0N NDP 7.06714
56 5J7X FAD 7.16332
57 1EFV FAD 7.45098
58 1EFV AMP 7.45098
59 1H5Q NAP 7.54717
60 4NBU NAI 7.6
61 4AT0 FAD 8.59599
62 4K26 NDP 9.42029
63 4K26 SFF 9.42029
64 2WDQ TEO 10.4348
65 6APL C5P 11.1748
66 5IGL BMF 15.4839
67 3QWI CUE 16.2963
68 3QWI NAP 16.2963
69 6CI9 F3V 17.3745
70 1XKQ NDP 17.5
71 2BOS GLA GAL GLC 20.5882
72 2BOS GLA GAL GLC NBU 20.5882
73 1OAA OAA 30
74 2FR1 NDP 40
Pocket No.: 3; Query (leader) PDB : 5DWQ; Ligand: SFG; Similar sites found with APoc: 16
This union binding pocket(no: 3) in the query (biounit: 5dwq.bio2) has 24 residues
No: Leader PDB Ligand Sequence Similarity
1 5A7Y SAH 1.60256
2 4LHD GLY 2.29226
3 4URF NAD 3.22581
4 1XE7 GUN 3.44828
5 4M7F BM3 3.53982
6 3GF4 FAD 3.72493
7 3GF4 UPG 3.72493
8 3UYW TAU 3.73832
9 2RH4 EMO 4.69314
10 5K4W NAI 5.29595
11 5K4W THR 5.29595
12 5KXE 6Y2 6.17284
13 2F7C CCU 6.43777
14 3BP1 GUN 7.93103
15 5YRM BGC GLC 11.9718
16 5YRG BGC GLC 11.9718
Pocket No.: 4; Query (leader) PDB : 5DWQ; Ligand: SFG; Similar sites found with APoc: 16
This union binding pocket(no: 4) in the query (biounit: 5dwq.bio2) has 24 residues
No: Leader PDB Ligand Sequence Similarity
1 3K1X DBX None
2 3T31 FAD 1.43266
3 6ER9 FAD 2.5788
4 1T9D P25 2.5788
5 1T9D 1MM 2.5788
6 1T9D PYD 2.5788
7 1CT9 GLN 2.86533
8 3RKR NAP 3.05344
9 4DDY DN6 4.56274
10 5A9A UTP 5.34979
11 5ZYN FAD 5.44413
12 1GTE FAD 5.73066
13 4OPC FDA 6.01719
14 2NVK FAD 8.88252
15 3AYI FAD 30
16 3AYI HCI 30
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