Receptor
PDB id Resolution Class Description Source Keywords
5DWQ 2.36 Å EC: 2.1.1.125 CRYSTAL STRUCTURE OF CARM1, SINEFUNGIN, AND METHYLATED H3 PE (R17) HOMO SAPIENS PROTEIN-SUBSTRATE TERNARY COMPLEX TRANSFERASE
Ref.: STRUCTURAL INSIGHTS INTO TERNARY COMPLEX FORMATION CARM1 WITH VARIOUS SUBSTRATES. ACS CHEM.BIOL. V. 11 763 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL A:502;
C:502;
C:503;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
SFG D:501;
A:501;
C:501;
B:501;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
381.387 C15 H23 N7 O5 c1nc(...
SO4 D:502;
B:502;
Invalid;
Invalid;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5DWQ 2.36 Å EC: 2.1.1.125 CRYSTAL STRUCTURE OF CARM1, SINEFUNGIN, AND METHYLATED H3 PE (R17) HOMO SAPIENS PROTEIN-SUBSTRATE TERNARY COMPLEX TRANSFERASE
Ref.: STRUCTURAL INSIGHTS INTO TERNARY COMPLEX FORMATION CARM1 WITH VARIOUS SUBSTRATES. ACS CHEM.BIOL. V. 11 763 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 5DWQ - SFG C15 H23 N7 O5 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 5DWQ - SFG C15 H23 N7 O5 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 5DWQ - SFG C15 H23 N7 O5 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SFG; Similar ligands found: 218
No: Ligand ECFP6 Tc MDL keys Tc
1 SFG 1 1
2 0UM 0.689655 0.887324
3 SAI 0.654762 0.940298
4 SA8 0.642857 0.9
5 SAH 0.635294 0.954545
6 EEM 0.62069 0.875
7 5X8 0.619048 0.924242
8 S7M 0.606742 0.875
9 RAB 0.597222 0.850746
10 XYA 0.597222 0.850746
11 ADN 0.597222 0.850746
12 5CD 0.594595 0.863636
13 5N5 0.581081 0.850746
14 62X 0.574468 0.84
15 A4D 0.573333 0.850746
16 K15 0.568421 0.863014
17 DTA 0.564103 0.84058
18 6RE 0.560976 0.833333
19 SAM 0.555556 0.875
20 EP4 0.551282 0.802817
21 KB1 0.55102 0.887324
22 M2T 0.544304 0.780822
23 SMM 0.537634 0.84
24 MTA 0.5375 0.826087
25 ZAS 0.53012 0.816901
26 A 0.53012 0.77027
27 AMP 0.53012 0.77027
28 J7C 0.529412 0.84507
29 3DH 0.52439 0.826087
30 GJV 0.523256 0.821918
31 SON 0.522727 0.813333
32 0XU 0.522222 0.938462
33 SRP 0.521277 0.813333
34 SSA 0.521277 0.697674
35 AMP MG 0.517647 0.75
36 AOC 0.517647 0.826087
37 CA0 0.516854 0.776316
38 5AL 0.516129 0.786667
39 AMO 0.515464 0.813333
40 DSZ 0.515464 0.717647
41 GSU 0.515152 0.738095
42 KH3 0.514286 0.851351
43 A2D 0.511628 0.75
44 A3N 0.511628 0.814286
45 ABM 0.511628 0.75
46 A5A 0.510638 0.682353
47 5CA 0.510417 0.697674
48 SRA 0.505882 0.730769
49 S4M 0.505747 0.792208
50 AN2 0.505618 0.74026
51 A7D 0.505618 0.882353
52 A3S 0.505618 0.895522
53 GAP 0.505376 0.776316
54 LSS 0.5 0.681818
55 VMS 0.5 0.666667
56 DSH 0.5 0.871429
57 AP2 0.5 0.766234
58 LAD 0.5 0.818182
59 ADX 0.5 0.678571
60 BA3 0.5 0.75
61 M33 0.5 0.74026
62 A12 0.5 0.766234
63 KAA 0.5 0.712644
64 54H 0.5 0.666667
65 Y3J 0.5 0.80303
66 SXZ 0.49505 0.875
67 ME8 0.49505 0.775
68 AHX 0.494949 0.759494
69 TSB 0.494845 0.674419
70 53H 0.494845 0.659091
71 G5A 0.494624 0.697674
72 50T 0.494505 0.74026
73 AP5 0.494382 0.75
74 5AS 0.494382 0.640449
75 ADP 0.494382 0.75
76 B4P 0.494382 0.75
77 8QN 0.489796 0.786667
78 GEK 0.489796 0.913043
79 5AD 0.486842 0.828125
80 PAJ 0.484848 0.728395
81 52H 0.484536 0.659091
82 AU1 0.483516 0.730769
83 ADP MG 0.483516 0.74026
84 MAO 0.483146 0.782051
85 NEC 0.482759 0.797101
86 A3G 0.482759 0.882353
87 3AM 0.482353 0.733333
88 YAP 0.480769 0.802632
89 7D7 0.480519 0.794118
90 TXA 0.480392 0.766234
91 NB8 0.480392 0.782051
92 NVA LMS 0.48 0.681818
93 DAL AMP 0.479592 0.786667
94 ATF 0.479167 0.721519
95 ATP 0.478261 0.75
96 BEF ADP 0.478261 0.721519
97 ACP 0.478261 0.753247
98 ADP BEF 0.478261 0.721519
99 A3T 0.478261 0.852941
100 7MD 0.476636 0.775
101 XAH 0.47619 0.775
102 YSA 0.47619 0.697674
103 PRX 0.473118 0.753247
104 APR 0.473118 0.773333
105 AR6 0.473118 0.773333
106 AQP 0.473118 0.75
107 APC 0.473118 0.766234
108 5FA 0.473118 0.75
109 WAQ 0.470588 0.815789
110 4AD 0.47 0.802632
111 NSS 0.47 0.697674
112 AD9 0.468085 0.730769
113 RBY 0.468085 0.789474
114 AGS 0.468085 0.7125
115 SAP 0.468085 0.7125
116 ADV 0.468085 0.789474
117 ADP PO3 0.468085 0.77027
118 A5D 0.468085 0.84058
119 MHZ 0.467391 0.782051
120 FA5 0.466667 0.813333
121 PTJ 0.466019 0.7375
122 00A 0.465347 0.746835
123 D3Y 0.464646 0.869565
124 ATP MG 0.463158 0.74026
125 VRT 0.463158 0.871429
126 LEU LMS 0.460784 0.662921
127 OOB 0.46 0.786667
128 S8M 0.46 0.859155
129 ADP VO4 0.459184 0.74026
130 VO4 ADP 0.459184 0.74026
131 ACQ 0.458333 0.753247
132 TAT 0.458333 0.721519
133 ANP 0.458333 0.730769
134 AAT 0.453608 0.847222
135 2AM 0.453488 0.723684
136 FYA 0.451923 0.786667
137 YLC 0.451327 0.797468
138 DLL 0.45098 0.786667
139 A3P 0.450549 0.746667
140 YLP 0.45045 0.777778
141 A22 0.45 0.74026
142 ADP ALF 0.44898 0.7125
143 ALF ADP 0.44898 0.7125
144 TYR AMP 0.448598 0.789474
145 2VA 0.446809 0.828571
146 3UK 0.446602 0.776316
147 OAD 0.446602 0.776316
148 ANP MG 0.444444 0.7125
149 IOT 0.443478 0.768293
150 9SN 0.443396 0.7375
151 P5A 0.442308 0.704545
152 PR8 0.442308 0.807692
153 7D5 0.44186 0.714286
154 A1R 0.441176 0.769231
155 7C5 0.440367 0.797297
156 TT8 0.44 0.926471
157 YLA 0.439655 0.777778
158 YLB 0.438596 0.777778
159 1ZZ 0.438095 0.753086
160 3OD 0.438095 0.776316
161 BIS 0.438095 0.725
162 NVA 2AD 0.4375 0.816901
163 MAP 0.435644 0.7125
164 MYR AMP 0.433962 0.753086
165 NAI 0.433628 0.725
166 SO8 0.43299 0.816901
167 A6D 0.432692 0.74359
168 5SV 0.431373 0.7375
169 25A 0.431373 0.75
170 TYM 0.429825 0.813333
171 WSA 0.429825 0.705882
172 3NZ 0.428571 0.833333
173 ARG AMP 0.428571 0.765432
174 LAQ 0.428571 0.753086
175 ADQ 0.427184 0.753247
176 7MC 0.426087 0.756098
177 48N 0.424779 0.759494
178 LPA AMP 0.424779 0.753086
179 JB6 0.424528 0.746835
180 PPS 0.424242 0.658824
181 AYB 0.423729 0.768293
182 PAP 0.42268 0.736842
183 OVE 0.422222 0.696203
184 3AD 0.421687 0.863636
185 4YB 0.419643 0.72093
186 CMP 0.419355 0.753425
187 2BA 0.419355 0.743243
188 A2P 0.419355 0.733333
189 ADP BMA 0.419048 0.753247
190 4UV 0.418182 0.75641
191 ALF ADP 3PG 0.417391 0.75
192 LA8 ALF 3PG 0.417391 0.75
193 AHZ 0.415929 0.731707
194 QQX 0.41573 0.670886
195 A A 0.415094 0.75
196 AP0 0.413793 0.695122
197 ATP A A A 0.412844 0.76
198 RP1 0.411111 0.705128
199 QQY 0.411111 0.679487
200 SP1 0.411111 0.705128
201 ACK 0.411111 0.716216
202 AFH 0.410714 0.728395
203 4UU 0.410714 0.75641
204 DND 0.408696 0.766234
205 TXD 0.408696 0.725
206 NXX 0.408696 0.766234
207 7D3 0.408602 0.696203
208 25L 0.407407 0.74026
209 CC5 0.407407 0.876923
210 TAD 0.40708 0.75
211 AMP DBH 0.405405 0.753247
212 TXE 0.405172 0.725
213 OMR 0.405172 0.743902
214 AF3 ADP 3PG 0.405172 0.75
215 MTP 0.404762 0.72973
216 N0B 0.401575 0.777778
217 V3L 0.4 0.773333
218 YLY 0.4 0.768293
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5DWQ; Ligand: SFG; Similar sites found: 279
This union binding pocket(no: 1) in the query (biounit: 5dwq.bio1) has 26 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5CLO NS8 0.0324 0.40326 None
2 4PIO AVI 0.0001898 0.41489 1.23839
3 4PIO SAH 0.0001775 0.41175 1.23839
4 4ONQ SFG 0.00002562 0.51634 1.43266
5 3LCC SAH 0.00000724 0.47742 1.70213
6 1FEC FAD 0.002645 0.43576 1.7192
7 3L9W GSH 0.001304 0.40242 1.7192
8 3L9W AMP 0.0007983 0.40162 1.7192
9 5EB3 UEG 0.002519 0.40211 1.88679
10 4UCI SAM 0.0005611 0.45289 2.00573
11 4TM3 FAD 0.007652 0.42922 2.00573
12 1OFS SUC 0.03588 0.40376 2.13904
13 3VYW SAM 0.0001482 0.47332 2.27273
14 1SQF SAM 0.0001498 0.48249 2.29226
15 1X87 NAD 0.003026 0.41129 2.29226
16 4D7E FAD 0.0001844 0.40415 2.29226
17 2WPB ZZI 0.02953 0.4046 2.30263
18 3O7W SAM 0.0000891 0.50899 2.38095
19 3LCV SAM 0.0004246 0.44608 2.4911
20 1DL5 SAH 0.00001465 0.48537 2.52366
21 3VC1 SAH 0.00003848 0.4886 2.5641
22 3VC1 GST 0.0001083 0.40593 2.5641
23 2CDU FAD 0.003177 0.42223 2.5788
24 1PS9 FAD 0.01233 0.40229 2.5788
25 2JHP SAH 0.01239 0.40093 2.5788
26 2B9W FAD 0.02342 0.40026 2.5788
27 1N2X SAM 0.0001758 0.4617 2.65781
28 1JQ3 AAT 0.00009243 0.42213 2.7027
29 3I53 SAH 0.0001768 0.47007 2.71084
30 2AOT SAH 0.00005626 0.51239 2.73973
31 1JQD SAH 0.0005423 0.41199 2.73973
32 3WV8 ATP 0.001782 0.43117 2.75229
33 1L1E SAH 0.00004012 0.49737 2.78746
34 3GU3 SAH 0.000007052 0.57605 2.8169
35 2JJQ SAH 0.00008892 0.50903 2.86533
36 4J36 1HR 0.002973 0.43077 2.86533
37 4J36 FAD 0.001633 0.4307 2.86533
38 3ICT ADP 0.007532 0.42211 2.86533
39 3ICS ADP 0.009397 0.41745 2.86533
40 5AHO TLA 0.005135 0.43861 2.97619
41 4NEC SAH 0.00004236 0.51807 3.0303
42 4AZT SAM 0.00006899 0.49735 3.15186
43 4AZW SAM 0.00006951 0.49211 3.15186
44 3K6V CIT 0.03395 0.40467 3.15186
45 3DXY SAM 0.000001307 0.60356 3.21101
46 3G89 SAM 0.000000911 0.60279 3.21285
47 3LTW HLZ 0.02971 0.41022 3.21429
48 3HAV SRY 0.01245 0.41976 3.34448
49 3FPF TNA 0.00002755 0.41621 3.3557
50 3FPF MTA 0.00002755 0.41621 3.3557
51 2CBZ ATP 0.007678 0.43203 3.37553
52 3LKZ SFG 0.0000705 0.49185 3.42679
53 5LOG SAH 0.00005982 0.49493 3.43348
54 5KOK SAH 0.00006717 0.49276 3.4384
55 2ZWA SAH 0.0005736 0.44449 3.4384
56 4CNK FAD 0.004424 0.41835 3.4384
57 2YVJ NAI 0.006468 0.41024 3.4384
58 5KOK S9T 0.0003215 0.40264 3.4384
59 4OBW SAM 0.0008435 0.44934 3.50195
60 4Z2S NDG 0.02134 0.41278 3.52113
61 4Z2S NAG 0.02134 0.41278 3.52113
62 2OFD NGA 0.03175 0.40375 3.52113
63 2OFE NAG 0.0322 0.40254 3.52113
64 2I7C AAT 0.00008064 0.42053 3.53357
65 5N5D SAM 0.00004321 0.46219 3.53982
66 3FRH SAH 0.0004211 0.43898 3.55731
67 5N53 8NB 0.01787 0.41698 3.58974
68 2O07 MTA 0.0002393 0.43334 3.61842
69 2O07 SPD 0.0002604 0.42115 3.61842
70 2VDV SAM 0.000007543 0.55952 3.65854
71 3OU2 SAH 0.00003528 0.47873 3.66972
72 2ZFU SAH 0.00003924 0.46757 3.72093
73 3VSE SAH 0.00007133 0.51978 3.72493
74 1NW5 SAM 0.00006247 0.49412 3.76176
75 5KVA SAM 0.00001354 0.51213 3.95683
76 3P2E SAH 0.0001415 0.47417 4
77 4POO SAM 0.0001089 0.46603 4
78 3Q9T FAY 0.007057 0.40869 4.01146
79 1VHZ APR 0.02112 0.41286 4.0404
80 2PT9 S4M 0.00007524 0.46536 4.04984
81 2PT9 2MH 0.0001593 0.40984 4.04984
82 2VGD XYP XYP 0.02319 0.4075 4.12844
83 3JWH SAH 0.000004596 0.46088 4.14747
84 1V59 NAD 0.00009495 0.51379 4.1841
85 3C3Y SAH 0.001537 0.43395 4.21941
86 5XVK SAH 0.0008273 0.43427 4.22535
87 5MGZ SAH 0.00004488 0.50033 4.23729
88 2PZM NAD 0.009658 0.40868 4.24242
89 2PZM UDP 0.009658 0.40868 4.24242
90 1LSS NAD 0.0002397 0.46446 4.28571
91 3C6K MTA 0.0002346 0.46984 4.29799
92 3C6K SPD 0.0002346 0.46984 4.29799
93 1QO8 FAD 0.002756 0.43121 4.29799
94 2PNC CLU 0.01497 0.42275 4.29799
95 1X14 NAD 0.007527 0.41074 4.29799
96 2BZG SAH 0.000003236 0.55601 4.31034
97 5M58 SAH 0.00008966 0.48733 4.34783
98 3SAO DBH 0.02834 0.41214 4.375
99 1R18 SAH 0.00001366 0.51196 4.40529
100 4GLL NAD 0.007372 0.40225 4.45104
101 3MA0 XYP 0.03361 0.40301 4.47284
102 5EB4 FAD 0.00225 0.43295 4.58453
103 4FZV SAM 0.00001952 0.51063 4.60251
104 1G60 SAM 0.0001409 0.47885 4.61538
105 1HSR BHO 0.01231 0.41035 4.65116
106 4II2 ATP 0.001533 0.43029 4.81928
107 2PX8 SAH 0.0004936 0.45962 4.83271
108 4KRI SAH 0.000003928 0.54014 4.87106
109 1KYZ SAH 0.0001002 0.49538 4.87106
110 3TKY SAH 0.0001188 0.44763 4.87106
111 5DNK SAH 0.000009384 0.4427 4.87106
112 5F8F SFG 0.00003145 0.52403 5.15759
113 3PT9 SAH 0.00001988 0.5212 5.15759
114 3S1S SAH 0.0000365 0.48953 5.15759
115 1Y8Q ATP 0.0002811 0.44955 5.20231
116 3BGD SAH 0.00001083 0.51104 5.38462
117 3BGD PM6 0.00002544 0.46956 5.38462
118 1RJD SAM 0.0003497 0.43307 5.38922
119 3DMH SAM 0.0000006795 0.57244 5.44413
120 3DMH GMP 0.000002099 0.50841 5.44413
121 5FTW SAH 0.003008 0.41787 5.46875
122 2UYQ SAM 0.002112 0.46379 5.48387
123 4BLW SAH 0.00007981 0.45849 5.53633
124 4BLW AMP 0.0001046 0.42007 5.53633
125 2P41 SAH 0.00002682 0.51546 5.57377
126 5XVQ SAH 0.001021 0.43053 5.6338
127 4IWN GEK 0.0000007884 0.55744 5.67686
128 2AWN ADP 0.007397 0.4351 5.73066
129 1I1N SAH 0.00001409 0.47933 5.75221
130 3A4T SFG 0.000002558 0.5422 5.83942
131 3A25 SAM 0.00001749 0.52366 5.98007
132 3FZG SAM 0.0003969 0.47329 6
133 4KXQ APR 0.006354 0.40103 6.04982
134 2ZIF SAM 0.000008175 0.53231 6.06061
135 1I9G SAM 0.000004973 0.5358 6.07143
136 1Q0S SAH 0.00007255 0.47309 6.17761
137 3EVG SAH 0.0000249 0.51688 6.18182
138 2FJK 13P 0.01598 0.41013 6.22951
139 1U2Z SAH 0.00000136 0.53609 6.30372
140 3UCL FAD 0.008038 0.42639 6.30372
141 3UCL CYH 0.008038 0.42639 6.30372
142 3UCL NAP 0.008825 0.42639 6.30372
143 5E72 SAM 0.000004661 0.50948 6.35838
144 5E9W SAH 0.00007398 0.4239 6.41026
145 3QOX SAH 0.000003966 0.51747 6.59026
146 4KIB SAH 0.000003142 0.49187 6.59026
147 1ELI PYC 0.001249 0.44163 6.59026
148 1ZMD NAI 0.001079 0.4207 6.59026
149 1JNR FAD 0.03241 0.40317 6.66667
150 2WSB NAD 0.009201 0.40681 6.69291
151 1VBO MAN MAN MAN 0.02494 0.4121 6.71141
152 3HVJ 705 0.00000113 0.4615 6.78733
153 4DMG SAM 0.0002172 0.49646 6.87023
154 3GDN FAD 0.001783 0.43934 6.87679
155 3GDN HBX 0.002631 0.43934 6.87679
156 3NTD FAD 0.007941 0.40756 6.87679
157 5MW4 5JU 0.000004709 0.42903 6.88623
158 1QAN SAH 0.00002158 0.5037 6.96721
159 3Q87 SAM 0.00001485 0.50546 7.05882
160 5ULP KB1 0.00002161 0.49414 7.08955
161 5K7U SAM 0.007063 0.40854 7.16332
162 2J5V RGP 0.01022 0.43028 7.44986
163 5E1M SAH 0.00004093 0.43006 7.46888
164 5E1M PRO PRO LYS ARG ILE ALA 0.00004093 0.43006 7.46888
165 5DLY SAH 0.00004078 0.41654 7.5188
166 5DLY 5D7 0.00004725 0.40668 7.5188
167 2EJU SAH 0.000002275 0.56276 7.73639
168 5HJM MTA 0.00000194 0.55933 7.73639
169 2WPF FAD 0.003182 0.45817 7.73639
170 2WPF WPF 0.003672 0.45667 7.73639
171 1FP1 SAH 0.002979 0.42454 7.73639
172 1EJ0 SAM 0.00005932 0.50024 7.77778
173 4GK9 MAN BMA MAN MAN MAN 0.02886 0.41746 7.8853
174 5THY SAH 0.0002286 0.46533 7.90123
175 4RDH AMP 0.00119 0.45131 7.98611
176 4RDI ATP 0.001841 0.43437 7.98611
177 5X62 SAH 0.000002792 0.56549 8.02292
178 5THZ SAH 0.0003537 0.44164 8.14815
179 4MIG G3F 0.001721 0.44569 8.30946
180 4D79 ATP 0.002538 0.42821 8.33333
181 2VT3 ATP 0.007995 0.42085 8.37209
182 1KYQ NAD 0.002507 0.43232 8.39416
183 3MQ2 SAH 0.0002646 0.47636 8.7156
184 1G55 SAH 0.00001484 0.52112 8.74636
185 3IWD M2T 0.01291 0.41852 8.82353
186 1IM8 SAI 0.0000002239 0.59287 9.01639
187 2A14 SAH 0.0007374 0.43996 9.12547
188 5MPT SAH 0.0001858 0.47835 9.16905
189 2GVC FAD 0.002296 0.42454 9.16905
190 5JE0 SAH 0.000004435 0.47752 9.31174
191 5JE0 AZ8 0.000004435 0.47752 9.31174
192 5JGL SAM 0.0002833 0.47503 9.34256
193 2F5Z FAD 0.001558 0.44286 9.375
194 3M6W SAM 0.0003194 0.47763 9.45559
195 3GWZ SAH 0.0009172 0.46126 9.45559
196 3GXO SAH 0.001546 0.44606 9.45559
197 3H8V ATP 0.003131 0.42418 9.45559
198 4PNE SAH 0.00007885 0.47589 9.60265
199 5DM1 SAH 0.00002385 0.41836 9.73783
200 5DM1 5D7 0.00002476 0.41392 9.73783
201 5JJR SAH 0.00003803 0.50877 10.0287
202 2FK8 SAM 0.00004356 0.49585 10.0629
203 3OFK SAH 0.000147 0.46908 10.1852
204 3FUU ADN 0.00005835 0.4954 10.3321
205 5TVF CGQ 0.02839 0.40145 10.5882
206 2FKA BEF 0.01038 0.40598 10.8527
207 1ZQ9 SAM 0.0001833 0.47861 10.8772
208 3EGV SAH 0.0000005082 0.59885 11.0236
209 2NXE SAM 0.000001062 0.57736 11.0236
210 2YX1 SFG 0.0000006627 0.6093 11.3095
211 1KPG SAH 0.00001219 0.51402 11.4983
212 3TLJ SAH 0.00003905 0.48833 12.0344
213 5DQY BEZ 0.03164 0.4032 12.381
214 2PXX SAH 0.00004386 0.50076 12.5581
215 1XDS SAM 0.0005213 0.47283 12.6074
216 4N49 SAM 0.0005397 0.44952 12.6074
217 2WA2 SAM 0.00008386 0.43739 12.6812
218 1JG3 ADN 0.00005157 0.50293 12.766
219 1GET NAP 0.001902 0.4567 12.894
220 1GET FAD 0.001778 0.4567 12.894
221 5CUQ NSC 0.0001659 0.47051 13.1086
222 1QZZ SAM 0.002242 0.44296 13.467
223 1NV8 SAM 0.000001234 0.51028 13.7324
224 1NV8 MEQ 0.000006149 0.49286 13.7324
225 3DUW SAH 0.00001919 0.51628 13.9013
226 5X7Q GLC GLC GLC GLC 0.004057 0.42835 14.3266
227 5X7Q GLC GLC GLC 0.007011 0.41878 14.3266
228 2XYQ SAH 0.0002312 0.47416 14.4828
229 4DCM SAM 0.00002164 0.53151 14.6132
230 4QTU SAM 0.00001005 0.52843 14.8148
231 4M73 SAH 0.000001742 0.46097 14.8368
232 4M73 M72 0.00002618 0.42381 14.8368
233 1TPY SAH 0.00001474 0.51059 14.9826
234 2HNK SAH 0.0001378 0.47465 15.0628
235 3A27 SAM 0.000001641 0.56902 15.0735
236 4KRG SAH 0.000003772 0.5596 15.1862
237 3H2B SAH 0.0000001149 0.6124 15.2709
238 3GDH SAH 0.00001821 0.49711 15.3527
239 5GM1 SAH 0.0000714 0.47765 15.8249
240 1XTP SAI 0.00000158 0.56975 16.1417
241 1Z3C SA8 0.00006314 0.44307 17.1141
242 3BXO SAM 0.00001206 0.54993 17.1548
243 2DPM SAM 0.00004509 0.49041 17.2535
244 2XVM SAH 0.00002815 0.53257 17.5879
245 3EGI ADP 0.00003222 0.55893 17.9612
246 1KPH SAH 0.00001231 0.51384 18.4669
247 4XUC SAM 0.00000445 0.45977 18.8073
248 4XUC 43G 0.00000445 0.45977 18.8073
249 2PWY SAH 0.0008328 0.46038 19.3798
250 4FC7 COA 0.01097 0.40539 19.4946
251 4FC7 NAP 0.01097 0.40539 19.4946
252 1XCL SAH 0.00003202 0.44348 19.5745
253 3X0D SAH 0.0000000001192 0.74145 19.7708
254 4X60 SFG 0.00000009996 0.47924 19.7708
255 4X60 3XV 0.0000001094 0.4728 19.7708
256 3T7S SAM 0.00001049 0.53346 19.7761
257 5BW4 SAM 0.00001119 0.53831 20
258 1WY7 SAH 0.000004294 0.53285 20.7729
259 4R6W SAH 0.00001694 0.45067 20.9302
260 5FA8 SAM 0.0000006949 0.55967 21.118
261 4C4A SAH 0.0000000002104 0.73077 21.2034
262 5L95 AMP 0.003607 0.41792 21.25
263 1VE3 SAM 0.00002011 0.52098 21.5859
264 1P1C SAH 0.00007641 0.47645 23.1156
265 5E8J SAH 0.0000522 0.51993 25
266 4YMH SAH 0.00001462 0.51595 25
267 1L3I SAH 0.00002206 0.48589 26.0417
268 2EG5 SAH 0.00005559 0.51864 30
269 3GCZ SAM 0.0000462 0.50504 30
270 1YXM ADE 0.003266 0.44028 30
271 3GRU AMP 0.00001512 0.50513 35
272 1WG8 SAM 0.00002768 0.48984 35
273 1N4W FAD 0.001734 0.44085 35
274 4XFR CIT 0.01797 0.41198 35
275 4M38 SAH 0.000000002415 0.67624 35.5685
276 3G2O SAM 0.000004415 0.55005 45
277 4LWP SAH 0.000000000002369 0.82685 45.8453
278 4Y2H SAH 0.00000000000008593 0.87461 48.1375
279 4Y2H 49K 0.0000000000007002 0.83588 48.1375
Pocket No.: 2; Query (leader) PDB : 5DWQ; Ligand: SFG; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 5dwq.bio1) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 5DWQ; Ligand: SFG; Similar sites found: 16
This union binding pocket(no: 3) in the query (biounit: 5dwq.bio2) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5A7Y SAH 0.02582 0.40062 1.60256
2 2V57 PRL 0.02362 0.40719 2.63158
3 1OYF MHN 0.02594 0.40636 3.30579
4 3N9R TD3 0.01977 0.40651 3.58306
5 1PR9 NAP 0.00946 0.40438 3.68852
6 3UYW TAU 0.0336 0.40428 3.73832
7 2YY7 NAD 0.009222 0.40247 3.84615
8 4N9Z V3L 0.02386 0.40162 4.01146
9 1BC5 SAH 0.003629 0.40281 4.83271
10 2YGM GLA NAG GAL FUC 0.01676 0.41013 5.44413
11 5KXE 6Y2 0.03326 0.40011 6.17284
12 5GWX SAR 0.001746 0.40174 8.09859
13 5GWX SAM 0.001746 0.40174 8.09859
14 2WDQ TEO 0.02652 0.40413 10.4348
15 2BOS GLA GAL GLC 0.02248 0.40831 20.5882
16 2BOS GLA GAL GLC NBU 0.02801 0.40234 20.5882
Pocket No.: 4; Query (leader) PDB : 5DWQ; Ligand: SFG; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 5dwq.bio2) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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