Receptor
PDB id Resolution Class Description Source Keywords
5EB4 2.3 Å NON-ENZYME: OTHER THE CRYSTAL STRUCTURE OF ALMOND HNL, PAHNL5 V317A, EXPRESSED ASPERGILLUS NIGER PRUNUS DULCIS HYDROXYNITRILE LYASE PRUNUS AMYGDALUS ASPERGILLUS NIGER L
Ref.: STRUCTURES OF ALMOND HYDROXYNITRILE LYASE ISOENZYME PROVIDE A RATIONALE FOR THE LACK OF OXIDOREDUCTASE IN FLAVIN DEPENDENT HNLS. J.BIOTECHNOL. V. 235 24 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NAG A:605;
B:603;
B:607;
A:604;
A:606;
A:601;
B:606;
A:607;
B:609;
B:608;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
221.208 C8 H15 N O6 CC(=O...
NAG NAG B:604;
B:601;
A:602;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
408.404 n/a O=C(N...
FAD B:610;
A:608;
Valid;
Valid;
none;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5EB4 2.3 Å NON-ENZYME: OTHER THE CRYSTAL STRUCTURE OF ALMOND HNL, PAHNL5 V317A, EXPRESSED ASPERGILLUS NIGER PRUNUS DULCIS HYDROXYNITRILE LYASE PRUNUS AMYGDALUS ASPERGILLUS NIGER L
Ref.: STRUCTURES OF ALMOND HYDROXYNITRILE LYASE ISOENZYME PROVIDE A RATIONALE FOR THE LACK OF OXIDOREDUCTASE IN FLAVIN DEPENDENT HNLS. J.BIOTECHNOL. V. 235 24 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 5EB4 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3GDP - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 1JU2 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
3 3GDN - HBX C7 H6 O c1ccc(cc1)....
4 5EB4 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3GDP - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 1JU2 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
3 3GDN - HBX C7 H6 O c1ccc(cc1)....
4 5EB4 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FAD; Similar ligands found: 119
No: Ligand ECFP6 Tc MDL keys Tc
1 FAS 1 1
2 FAD 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 6FA 0.794118 0.987654
6 DAL FAD PER 0.772414 0.951807
7 FAE 0.751773 0.987654
8 SFD 0.651007 0.860215
9 FDA 0.641892 0.906977
10 FNK 0.602564 0.876405
11 62F 0.572327 0.939024
12 F2N 0.566265 0.886364
13 FMN 0.543307 0.876543
14 FA9 0.526316 0.939759
15 6YU 0.516304 0.860215
16 CNV FAD 0.511905 0.908046
17 P6G FDA 0.511628 0.908046
18 FAD NBT 0.508876 0.83871
19 A2D 0.504065 0.875
20 P5F 0.491329 0.941176
21 FAD CNX 0.488506 0.8125
22 APR 0.488372 0.851852
23 AR6 0.488372 0.851852
24 AGS 0.484615 0.811765
25 SAP 0.484615 0.811765
26 M33 0.484375 0.864198
27 BA3 0.484127 0.875
28 FAD NBA 0.480663 0.802083
29 ATP 0.48062 0.851852
30 B4P 0.480315 0.875
31 ADP 0.480315 0.851852
32 AP5 0.480315 0.875
33 ANP 0.477273 0.831325
34 AQP 0.476923 0.851852
35 5FA 0.476923 0.851852
36 48N 0.469388 0.902439
37 OAD 0.467626 0.876543
38 GTA 0.465753 0.892857
39 AN2 0.465116 0.841463
40 AD9 0.462121 0.831325
41 3OD 0.460993 0.876543
42 RBF 0.460938 0.790123
43 FB0 0.460606 0.835165
44 139 0.460526 0.858824
45 AP0 0.46 0.835294
46 A22 0.459854 0.864198
47 ACP 0.458015 0.853659
48 8QN 0.456522 0.864198
49 PRX 0.454545 0.831325
50 A1R 0.453237 0.86747
51 G3A 0.452055 0.902439
52 T5A 0.45098 0.872093
53 G5P 0.44898 0.902439
54 ATF 0.448529 0.821429
55 50T 0.44697 0.819277
56 ACQ 0.444444 0.853659
57 PAJ 0.442857 0.847059
58 ADQ 0.442857 0.853659
59 5AL 0.441176 0.864198
60 ADX 0.439394 0.775281
61 CA0 0.439394 0.853659
62 A4P 0.437909 0.831461
63 25L 0.4375 0.864198
64 P33 FDA 0.436464 0.817204
65 5SV 0.435714 0.793103
66 TXE 0.434211 0.890244
67 OMR 0.434211 0.818182
68 ABM 0.434109 0.829268
69 A 0.433071 0.82716
70 AMP 0.433071 0.82716
71 4AD 0.432624 0.855422
72 ADJ 0.432258 0.818182
73 BIS 0.430556 0.802326
74 SRA 0.429688 0.788235
75 AFH 0.42953 0.825581
76 TXD 0.427632 0.890244
77 NXX 0.427632 0.865854
78 UP5 0.427632 0.878049
79 DND 0.427632 0.865854
80 6V0 0.427632 0.857143
81 SRP 0.42446 0.843373
82 PR8 0.423611 0.837209
83 TAT 0.423358 0.821429
84 AMO 0.422535 0.865854
85 PTJ 0.42069 0.835294
86 FYA 0.42069 0.864198
87 TXA 0.42069 0.865854
88 CNA 0.420382 0.865854
89 00A 0.41958 0.823529
90 AHX 0.41958 0.835294
91 MAP 0.41844 0.811765
92 NAI 0.418301 0.845238
93 AU1 0.41791 0.831325
94 AP2 0.416667 0.843373
95 A12 0.416667 0.843373
96 25A 0.415493 0.851852
97 AMP MG 0.415385 0.785714
98 COD 0.415094 0.842697
99 ADP BEF 0.414815 0.77907
100 BEF ADP 0.414815 0.77907
101 4TC 0.412903 0.879518
102 APC 0.411765 0.843373
103 NB8 0.410959 0.835294
104 ME8 0.410959 0.806818
105 1ZZ 0.410959 0.806818
106 4UW 0.409091 0.825581
107 NAX 0.409091 0.837209
108 RBY 0.408759 0.843373
109 ADV 0.408759 0.843373
110 ADP MG 0.407407 0.797619
111 P1H 0.405882 0.818182
112 OOB 0.405594 0.864198
113 A A 0.40411 0.829268
114 LAD 0.40411 0.825581
115 UPA 0.403846 0.86747
116 4UU 0.401316 0.833333
117 A3D 0.401235 0.876543
118 DLL 0.4 0.864198
119 XAH 0.4 0.806818
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5EB4; Ligand: FAD; Similar sites found: 514
This union binding pocket(no: 1) in the query (biounit: 5eb4.bio1) has 41 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4KRI SAH 0.005008 0.42711 0.923788
2 4JJF FE9 0.003118 0.41844 1.16279
3 4JJF N2I 0.005306 0.4042 1.16279
4 1ZMD NAI 0.000002233 0.5558 1.26582
5 1ZMD FAD 0.0000002279 0.51545 1.26582
6 3G5S FAD 0.000004179 0.49892 1.3544
7 4CP8 MLI 0.04725 0.41008 1.43737
8 2CUN 3PG 0.02221 0.43033 1.46341
9 4JDR FAD 0.0000006072 0.51191 1.47679
10 4C4A SAH 0.001674 0.45224 1.50376
11 1HYH NAD 0.0004997 0.44154 1.61812
12 2B9W FAD 0.000001683 0.52007 1.65094
13 5U8U FAD 0.000007681 0.40858 1.6632
14 2ZIF SAM 0.008196 0.42054 1.6835
15 5J7X FAD 0.000006482 0.48883 1.69173
16 5I39 FAD 0.000004533 0.49424 1.71569
17 4M52 FAD 0.000001099 0.49858 1.71674
18 4KRG SAH 0.02775 0.4047 1.71674
19 2A8X FAD 0.0000003007 0.51171 1.72414
20 4RDH AMP 0.00004419 0.54126 1.73611
21 4RDI ATP 0.00004344 0.53027 1.73611
22 1RJD SAM 0.01966 0.40025 1.79641
23 1YQZ FAD 0.00001051 0.41608 1.82648
24 2D2I NAP 0.0002889 0.4748 1.84211
25 4V15 PLP 0.03673 0.40496 1.84697
26 3LKZ SFG 0.001384 0.45604 1.86916
27 5TE1 7A2 0.03194 0.41534 1.8797
28 3AYI FAD 0.0000006116 0.46906 1.94175
29 3AYI HCI 0.0000006618 0.4645 1.94175
30 1O6Z NAD 0.00285 0.42857 1.9802
31 2CDU ADP 0.0000004204 0.6319 1.99115
32 2CDU FAD 0.000007078 0.49428 1.99115
33 2WPF WPF 0.000004905 0.53227 2.0202
34 2WPF FAD 0.000005679 0.52787 2.0202
35 3GRU AMP 0.0006985 0.45815 2.0339
36 1MUU NAD 0.0001823 0.47567 2.06422
37 1MV8 NAD 0.000251 0.46627 2.06422
38 3B20 NAD 0.001335 0.44262 2.0649
39 1GTE FAD 0.00001021 0.41282 2.06767
40 4DG8 AMP 0.03334 0.40075 2.06767
41 5JWC FAD 0.00001782 0.48323 2.11132
42 4E5N NAD 0.004794 0.40359 2.12121
43 5G3U FDA 0.00000009691 0.55234 2.12766
44 5G3U ITW 0.0000006163 0.49754 2.12766
45 2YVK MRU 0.02595 0.40308 2.13904
46 3AB1 FAD 0.0000003256 0.5263 2.22222
47 5WGR FAD 0.000005836 0.48391 2.25564
48 1X87 NAD 0.0001987 0.48185 2.25564
49 5UAO FAD 0.00004501 0.45955 2.25564
50 1GQ2 NAP 0.0007138 0.44136 2.25564
51 4AP3 NAP 0.000007087 0.41763 2.25564
52 4AP3 FAD 0.000007087 0.41763 2.25564
53 5HV7 RBL 0.01761 0.41031 2.25564
54 1YS4 NAP 0.00568 0.42157 2.25989
55 1OBB NAD 0.006024 0.41468 2.29167
56 1V59 NAD 0.00000009855 0.68869 2.30126
57 1V59 FAD 0.0000002094 0.50747 2.30126
58 4USF 6UI 0.03251 0.40771 2.30263
59 1X9I G6Q 0.04277 0.40153 2.31788
60 2VT3 ATP 0.00001724 0.57463 2.32558
61 1H82 FAD 0.0000001253 0.4759 2.33051
62 1H82 GZZ 0.0000001823 0.4545 2.33051
63 4OBW SAM 0.01188 0.41618 2.33463
64 2XVF FAD 0.000004203 0.49883 2.37069
65 2XVE FAD 0.0000183 0.40638 2.37069
66 3V1Y NAD 0.0005849 0.45113 2.37389
67 3ORF NAD 0.002881 0.41719 2.39044
68 2AOT SAH 0.003705 0.44754 2.39726
69 2Q1W NAD 0.00008528 0.46467 2.4024
70 1XDS SAM 0.009527 0.43118 2.40642
71 1QZZ SAM 0.01786 0.41752 2.40642
72 2IID FAD 0.0000001883 0.47344 2.40964
73 2IID PHE 0.0000001883 0.47344 2.40964
74 5MBX SP5 0.0000005459 0.4617 2.41449
75 5MBX FAD 0.0000005459 0.4617 2.41449
76 5EOU ATP 0.0085 0.41674 2.41935
77 3UCL FAD 0.00001588 0.49297 2.44361
78 3UCL CYH 0.00001588 0.49297 2.44361
79 3UCL NAP 0.00001867 0.49297 2.44361
80 5TUK FAD 0.000007096 0.52556 2.45098
81 4BGB ADP 0.02567 0.4004 2.46154
82 2PK3 A2R 0.01331 0.41083 2.49221
83 5CAE COA 0.00553 0.41627 2.53165
84 2CUL FAD 0.0000005763 0.53738 2.63158
85 5MQ6 NDP 0.00001848 0.52661 2.63158
86 1KNR FAD 0.000000694 0.51519 2.63158
87 1PN0 FAD 0.00003217 0.43208 2.63158
88 1PN0 IPH 0.00003461 0.42779 2.63158
89 1LJ8 NAD 0.00334 0.43178 2.63692
90 1M2W NAD 0.004521 0.42292 2.63692
91 1KK1 GNP 0.01952 0.42688 2.68293
92 1ZGS XMM 0.01202 0.44779 2.68456
93 3WQT ANP 0.01309 0.40826 2.68595
94 2YVF FAD 0.00484 0.42851 2.69608
95 2YVF NAD 0.005035 0.42851 2.69608
96 2GLX NDP 0.01182 0.40215 2.71084
97 1P31 EPU 0.01963 0.40591 2.73684
98 3H8V ATP 0.0000947 0.51444 2.73973
99 3BXF 13P 0.00778 0.42823 2.7451
100 3U31 NAD 0.005264 0.42303 2.75862
101 2OG2 MLI 0.01223 0.41615 2.78552
102 5LD5 NAD 0.0003872 0.46927 2.7933
103 1U1I NAD 0.00343 0.40235 2.80612
104 4TXI FAD 0.000001138 0.53917 2.81955
105 4D04 NAP 0.000004855 0.41686 2.81955
106 4D04 FAD 0.000004855 0.41686 2.81955
107 4C3Y FAD 0.000001487 0.49929 2.83019
108 4C3Y ANB 0.000002569 0.47042 2.83019
109 1X7D NAD 0.001534 0.42811 2.85714
110 1QMG APX 0.01014 0.40765 2.8626
111 4J36 FAD 0.000004163 0.51378 2.89157
112 4J36 1HR 0.00003498 0.44484 2.89157
113 5JH2 A2P 0.01113 0.43998 2.90323
114 5E1M SAH 0.009154 0.41529 2.90456
115 1G55 SAH 0.00942 0.41775 2.91545
116 3LAD FAD 0.0000002456 0.51958 2.94118
117 3C3Y SAH 0.00662 0.42481 2.95359
118 5X62 SAH 0.007421 0.42921 2.95567
119 3FG2 FAD 0.000006944 0.50546 2.9703
120 2PX8 SAH 0.01643 0.40955 2.97398
121 2ZXI FAD 0.00002798 0.46978 2.98273
122 5ULP KB1 0.004015 0.42221 2.98507
123 1GET FAD 0.0000005339 0.43061 3.00752
124 1GET NAP 0.0000006041 0.42458 3.00752
125 4AZT SAM 0.01168 0.41653 3.00752
126 5SXS NIZ 0.03656 0.41016 3.00752
127 2HJR APR 0.0005632 0.46221 3.04878
128 1QCI ADE 0.004205 0.45774 3.05344
129 3GF4 FAD 0.000002051 0.44828 3.07692
130 3GF4 UPG 0.000002031 0.43851 3.07692
131 1BW9 NAD 0.0002976 0.4782 3.08989
132 4TQG NDP 0.003546 0.41358 3.09598
133 1C1X NAD 0.0008845 0.44372 3.09859
134 1KPG SAH 0.005803 0.42116 3.13589
135 1L1E SAH 0.007081 0.42033 3.13589
136 1KPH SAH 0.006263 0.41969 3.13589
137 2IVD FAD 0.000000008897 0.59815 3.13808
138 3GFB NAD 0.00412 0.41353 3.14286
139 2DFV NAD 0.001837 0.42776 3.17003
140 4UP3 FAD 0.000001653 0.50243 3.18471
141 4UP3 NDP 0.0008931 0.45711 3.18471
142 2GMH FAD 0.0000004845 0.51521 3.19549
143 2JJQ SAH 0.001097 0.47798 3.19549
144 3S1S SAH 0.006562 0.41588 3.19549
145 1Z17 ILE 0.003823 0.4733 3.19767
146 5E9W SAH 0.003311 0.45848 3.20513
147 5E8J SAH 0.004201 0.44893 3.20513
148 4U60 SIA GAL BGC NGA GAL 0.01318 0.44055 3.21429
149 1FL2 FAD 0.0000003125 0.53073 3.22581
150 1GUZ NAD 0.003736 0.41268 3.22581
151 5KVA SAM 0.0006179 0.46418 3.23741
152 3OFK SAH 0.002665 0.43611 3.24074
153 1E1M FAD 0.000002088 0.44729 3.26087
154 1E1M NAP 0.000002088 0.44729 3.26087
155 4D7E FAD 0.00002037 0.47784 3.2634
156 1FEC FAD 0.0000027 0.50339 3.26531
157 1R55 097 0.04119 0.40934 3.27103
158 1YJQ NAP 0.003578 0.40388 3.30033
159 4U8P FDA 0.000001989 0.41655 3.31384
160 4U8P UDP 0.000002232 0.41064 3.31384
161 1LES GLC FRU 0.04991 0.40166 3.31492
162 3GDH SAH 0.005129 0.41767 3.3195
163 3T7S SAM 0.004699 0.4351 3.35821
164 4COV GLA GAL 0.04264 0.41059 3.37079
165 1BXK NAD 0.0002158 0.46208 3.38028
166 4MOP 2H5 0.000000002919 0.53323 3.38346
167 2RGO FAD 0.000001175 0.51837 3.38346
168 3UOY FAD 0.000002461 0.41334 3.38346
169 3UOY NAP 0.000002461 0.41334 3.38346
170 2E5V FAD 0.000001247 0.49326 3.38983
171 1F06 NDP 0.00356 0.40175 3.4375
172 1F06 2NP 0.00356 0.40175 3.4375
173 1WP4 NDP 0.008249 0.40127 3.46021
174 1USI PHE 0.01653 0.43666 3.46821
175 1Q0S SAH 0.00259 0.43034 3.4749
176 3RE4 TO1 0.02488 0.41733 3.48837
177 2YYY NAP 0.0004814 0.44819 3.49854
178 4N49 SAM 0.0041 0.43103 3.50467
179 3QJ4 FAD 0.00000004837 0.56284 3.50877
180 2X3N FAD 0.00005209 0.46025 3.50877
181 4RPL FAD 0.000002926 0.42121 3.50877
182 4RPL 3UC 0.000004791 0.40926 3.50877
183 5KOK SAH 0.007923 0.42122 3.52645
184 1ZH8 NAP 0.004967 0.41023 3.52941
185 1I9G SAM 0.003213 0.43581 3.57143
186 4YRY FAD 0.000001169 0.49761 3.62319
187 4YRY NAD 0.000003212 0.44306 3.62319
188 1F8G NAD 0.0004688 0.46948 3.64583
189 5EVY FAD 0.00109 0.44976 3.65297
190 1D4D FAD 0.0000001063 0.52665 3.67133
191 2RAB FAD 0.0000002134 0.51157 3.67171
192 2RAB NAD 0.0000008242 0.42835 3.67171
193 1P77 ATR 0.0001131 0.55355 3.67647
194 5MZI FYK 0.00002594 0.40333 3.68764
195 5MZI FAD 0.00003051 0.40133 3.68764
196 2WET FAD 0.000003559 0.48632 3.7182
197 5TS5 FAD 0.00000003969 0.55109 3.71901
198 2RGJ FAD 0.000001906 0.52648 3.73134
199 3WGT FAD 0.000001236 0.47754 3.7464
200 3WGT QSC 0.000001345 0.47266 3.7464
201 3ZNN 4WL 0.00000494 0.43321 3.7464
202 3ZNN FAD 0.00000494 0.43321 3.7464
203 3TLJ SAH 0.009178 0.40953 3.75335
204 2Z3Y F2N 0.00000005508 0.53526 3.7594
205 1HGX 5GP 0.007341 0.44965 3.82514
206 1TPY SAH 0.005754 0.42132 3.83275
207 3BGD SAH 0.0159 0.40726 3.84615
208 5VN0 FAD 0.00000514 0.49234 3.861
209 5VN0 NAI 0.00002828 0.4037 3.861
210 3EGI ADP 0.001283 0.49593 3.8835
211 5TUF FAD 0.00003785 0.4813 3.91198
212 4UTU LRY 0.0217 0.41327 3.93013
213 4UTW RFW 0.02225 0.40942 3.93013
214 5TTJ FAD 0.0000002087 0.53675 3.94737
215 4IV9 FAD 0.0000002388 0.53086 3.94737
216 5EOW FAD 0.000009985 0.49591 3.95062
217 2R4J FAD 0.000002573 0.45146 3.99202
218 2R4J 13P 0.000002573 0.45146 3.99202
219 4FWE FAD 0.00000006886 0.53221 4.0201
220 1SW0 PGA 0.02423 0.41429 4.03226
221 1IXI 2HP 0.03394 0.41869 4.04984
222 1F3L SAH 0.007582 0.41601 4.04984
223 3JV7 NAD 0.004609 0.4066 4.05797
224 4K28 NAD 0.001507 0.43723 4.08922
225 1QAN SAH 0.002802 0.43516 4.09836
226 5MPT SAH 0.01025 0.41921 4.10628
227 4GUS FAD 0.00000007392 0.52596 4.12371
228 4HSU FAD 0.00000009589 0.52238 4.12371
229 4GUT FAD 0.00000008293 0.51456 4.12371
230 1DJN ADP 0.0000002168 0.61039 4.13534
231 1QO8 FAD 0.0000002168 0.52192 4.13534
232 4EMI FAD 0.000004839 0.49325 4.14634
233 4EMI NAD 0.00002657 0.40331 4.14634
234 4USR FAD 0.0000005285 0.54735 4.15512
235 1L7E NAI 0.0006594 0.45569 4.16667
236 3WMX NAD 0.003232 0.42052 4.18994
237 5JCA FAD 0.0000005032 0.50894 4.22535
238 5JCA NDP 0.000006254 0.41315 4.22535
239 5MGZ SAH 0.01189 0.41309 4.23729
240 2G5C NAD 0.001675 0.42387 4.27046
241 2Y6Q FAD 0.00000172 0.53235 4.27136
242 2Y6Q I7T 0.00002197 0.43901 4.27136
243 2CVQ NDP 0.005611 0.40562 4.28135
244 2JB2 FAD 0.0000003084 0.53093 4.29448
245 2JB2 PHE 0.000000389 0.52369 4.29448
246 4EUE NAI 0.002329 0.41326 4.30622
247 3X0D SAH 0.002084 0.44787 4.32331
248 3DMH SAM 0.003995 0.43154 4.32331
249 3GMB FAD 0.00001964 0.48508 4.33735
250 1W62 PYC 0.009583 0.44815 4.34783
251 4YCA NDP 0.0007001 0.44791 4.42177
252 3O7W SAM 0.007268 0.43706 4.42177
253 3H2B SAH 0.002248 0.44636 4.4335
254 1EJ0 SAM 0.0007104 0.47351 4.44444
255 1T36 U 0.02499 0.40095 4.45026
256 3C6K SPD 0.002359 0.40392 4.46194
257 3C6K MTA 0.002359 0.40392 4.46194
258 4ZRN NAD 0.0003171 0.44051 4.48718
259 3E1T FAD 0.000002562 0.48154 4.49219
260 5DNK SAH 0.001256 0.48506 4.51128
261 3NTD FAD 0.000005648 0.47868 4.51128
262 4L77 CNL 0.02784 0.41857 4.52261
263 3S5W NAP 0.00003127 0.54857 4.53564
264 3S5W FAD 0.000002065 0.53361 4.53564
265 2D3S TNR 0.01207 0.42604 4.54545
266 5HJM MTA 0.006273 0.42588 4.54545
267 4DSG UDP 0.00001682 0.4118 4.54545
268 4DSG FAD 0.00001682 0.4118 4.54545
269 2EG5 SAH 0.005124 0.44463 4.56989
270 3LXD FAD 0.000003107 0.51079 4.57831
271 5DWQ SFG 0.00225 0.43295 4.58453
272 5DX0 SFG 0.002586 0.42738 4.58453
273 5DX8 SFG 0.007569 0.41318 4.58453
274 5DXA SFG 0.007697 0.41286 4.58453
275 5DX1 SFG 0.006524 0.41051 4.58453
276 3ICT ADP 0.0000006153 0.64824 4.59184
277 3ICS ADP 0.0000007263 0.64458 4.59184
278 3ICT FAD 0.0000007949 0.52436 4.59184
279 3ICR FAD 0.000001141 0.51882 4.59184
280 3ICS FAD 0.000001128 0.51526 4.59184
281 5GZ6 NDP 0.0005388 0.47074 4.60123
282 5GZ6 7C3 0.0009037 0.4533 4.60123
283 1ORR NAD 0.0008127 0.42801 4.61095
284 1ELI PYC 0.000004558 0.48126 4.62725
285 5JE8 NAD 0.0004615 0.45877 4.63576
286 4REP FAD 0.0000001327 0.54349 4.64646
287 2F1K NAP 0.0002046 0.46992 4.6595
288 5BUK FAD 0.000001939 0.48055 4.66667
289 5TFZ 7BC 0.03195 0.41533 4.66667
290 2A92 NAI 0.002962 0.40928 4.6729
291 1IMB LIP 0.02525 0.40995 4.69314
292 4G74 FAD 0.00003052 0.47155 4.69925
293 4G74 UQ5 0.0000789 0.42198 4.69925
294 3NYC FAD 0.000002559 0.45531 4.72441
295 3NYC IAR 0.000002559 0.45531 4.72441
296 1DL5 SAH 0.003415 0.41953 4.73186
297 1L7N ALF 0.04347 0.40402 4.73934
298 1GY8 NAD 0.0005093 0.44123 4.78589
299 1NVM NAD 0.0009385 0.43097 4.80769
300 4UCI SAM 0.007554 0.42217 4.81928
301 1QR0 COA 0.03921 0.40689 4.82456
302 1DJL NAP 0.003 0.40675 4.83092
303 5BR7 FAD 0.000003977 0.42326 4.83461
304 5BR7 FLC 0.00003004 0.40147 4.83461
305 3VPH NAD 0.001876 0.41439 4.83871
306 3VPH OXM 0.003448 0.4001 4.83871
307 2PZM NAD 0.0009748 0.4119 4.84848
308 2PZM UDP 0.0009748 0.4119 4.84848
309 1WDK NAD 0.0005289 0.4634 4.87179
310 1ZQ9 SAM 0.0005827 0.47753 4.91228
311 3LU1 NAD 0.001351 0.42755 4.94506
312 3SAO DBH 0.01351 0.45214 5
313 4POO SAM 0.005242 0.41726 5
314 1M0S CIT 0.02152 0.42459 5.02283
315 4X9M FAD 0.000001205 0.50708 5.02392
316 3ITJ FAD 0.000004375 0.45251 5.02959
317 3OZ2 FAD 0.000004791 0.4868 5.03778
318 4B1W ATP 0.01555 0.40215 5.05319
319 3L4S NAD 0.001148 0.42495 5.05952
320 3L4S 3PG 0.00141 0.41904 5.05952
321 3PT9 SAH 0.007345 0.426 5.07519
322 2HK9 ATR 0.0002673 0.52004 5.09091
323 2HK9 NAP 0.002359 0.42616 5.09091
324 2Q0L FAD 0.000000786 0.50805 5.14469
325 2Q0L NAP 0.0009271 0.47687 5.14469
326 4MO2 FDA 0.000000268 0.54103 5.16304
327 4MO2 FAD 0.0000003386 0.53344 5.16304
328 4LWP SAH 0.002714 0.44626 5.16304
329 1I8T FAD 0.0000007105 0.51849 5.17711
330 1V8B NAD 0.001294 0.41326 5.21921
331 4XDZ NDP 0.008595 0.40547 5.24781
332 3NT6 FAD 0.000001956 0.50694 5.26316
333 3NTA FAD 0.000006215 0.48947 5.26316
334 1VM6 NAD 0.00343 0.42224 5.26316
335 4NKT 2KH 0.02358 0.41145 5.27859
336 2YG3 FAD 0.00000006743 0.54944 5.29801
337 4NEC SAH 0.01055 0.42533 5.30303
338 5CSS G3P 0.0237 0.41845 5.30973
339 1GZ6 NAI 0.005517 0.40123 5.32915
340 3L8G GMB 0.04717 0.40989 5.34759
341 4JF5 FLC 0.04534 0.40021 5.34979
342 2PV7 NAD 0.001265 0.43434 5.36913
343 3BFX A3P 0.01526 0.41107 5.40541
344 3CGB FAD 0.000001936 0.51071 5.41667
345 5U5G NAP 0.007338 0.40096 5.42373
346 1D4O NAP 0.001565 0.43351 5.43478
347 1HSL HIS 0.04774 0.40941 5.46218
348 2V3B FAD 0.0000148 0.47954 5.46875
349 2V3A FAD 0.00001232 0.47913 5.46875
350 2D3Y DU 0.04178 0.41664 5.47945
351 3NRZ MTE 0.02242 0.40035 5.4878
352 3OU2 SAH 0.01052 0.40178 5.50459
353 2B4R AES 0.0007105 0.4385 5.50725
354 2B4R NAD 0.001039 0.42926 5.50725
355 1XTP SAI 0.005299 0.43265 5.51181
356 2O07 MTA 0.001288 0.43402 5.59211
357 2O07 SPD 0.001844 0.42223 5.59211
358 2BZG SAH 0.01484 0.41164 5.60345
359 1PL6 NAD 0.001913 0.44595 5.61798
360 4CNK FAD 0.00000003083 0.55323 5.6266
361 2VVM FAD 0.0000001297 0.53983 5.65657
362 2VVL FAD 0.0000001613 0.53131 5.65657
363 3NJ4 NAD 0.01035 0.41034 5.74713
364 5X20 NAD 0.005877 0.41242 5.76923
365 5OFW 9TW 0.02842 0.42644 5.8296
366 2Q7V FAD 0.00000003159 0.55442 5.84615
367 2PT9 S4M 0.002452 0.42835 5.919
368 5FJN FAD 0.00000153 0.49432 5.92105
369 5FJN BE2 0.000002008 0.47777 5.92105
370 3LCC SAH 0.003719 0.44356 5.95745
371 5BW4 SAM 0.0005193 0.48439 5.99251
372 1JNR FAD 0.000002543 0.52901 6
373 5LOG SAH 0.002977 0.44076 6.00858
374 4MIG G3F 0.000000009867 0.59082 6.01504
375 1VL1 CIT 0.01135 0.44523 6.03448
376 2VYN NAD 0.001197 0.4324 6.0423
377 3NKS FAD 0.0000001113 0.5545 6.07966
378 1ZEM NAD 0.001522 0.434 6.10687
379 1IM8 SAI 0.003088 0.43659 6.14754
380 3N9R TD3 0.04921 0.40164 6.18893
381 1Q9I FAD 0.0000009534 0.45172 6.20301
382 1Q9I TEO 0.0000009534 0.45172 6.20301
383 2HNK SAH 0.002703 0.43919 6.27615
384 3B9Q MLI 0.01391 0.43134 6.29139
385 3HDY FAD 0.00001137 0.41252 6.29723
386 3HDY FDA 0.00001334 0.41098 6.29723
387 3HDY GDU 0.00001415 0.40793 6.29723
388 1CER NAD 0.000363 0.45966 6.34441
389 1N4W FAD 0.0000000000002779 0.70448 6.34921
390 5JJR SAH 0.001929 0.45321 6.39098
391 1O94 ADP 0.0000004227 0.59183 6.43939
392 1OMO NAD 0.0004275 0.46372 6.52174
393 1DQN IMU 0.02655 0.41968 6.52174
394 2P41 SAH 0.005361 0.43241 6.55738
395 1DAR GDP 0.04251 0.40503 6.57895
396 4USQ FAD 0.0003918 0.44742 6.6482
397 2I7C AAT 0.001519 0.41541 6.71378
398 2F5X ASP 0.03728 0.4163 6.73077
399 1PS9 FAD 0.0000004054 0.52464 6.76692
400 1L3I SAH 0.001631 0.43578 6.77083
401 4D3F NAP 0.003165 0.43281 6.77419
402 1SQK ADP 0.02029 0.4114 6.89655
403 3SJH ATP 0.01103 0.41162 6.93333
404 1X14 NAD 0.00005421 0.53121 6.98254
405 4J56 FAD 0.0000002386 0.5099 7.01754
406 1UJ5 5RP 0.04424 0.40077 7.04846
407 1OJ4 ANP 0.0182 0.41051 7.06714
408 2HQM FAD 0.0000001417 0.52746 7.14286
409 2V6G NAP 0.0002247 0.45495 7.14286
410 1J49 NAD 0.001841 0.42495 7.20721
411 3BF1 PAU 0.01911 0.4196 7.22892
412 3EVG SAH 0.006778 0.42763 7.27273
413 3DXY SAM 0.001235 0.48028 7.33945
414 2YY7 NAD 0.003516 0.4088 7.37179
415 3FUU ADN 0.0004116 0.4802 7.38007
416 4QTU SAM 0.00171 0.45182 7.40741
417 3AD8 NAD 0.00000002906 0.58945 7.42574
418 3AD8 FAD 0.000002697 0.41871 7.42574
419 3AD8 PYC 0.000002697 0.41871 7.42574
420 4YMH SAH 0.004028 0.4251 7.5
421 1Y8Q ATP 0.00001174 0.53028 7.51445
422 2PS1 ORO 0.01464 0.4336 7.52212
423 1EZ4 NAD 0.0009288 0.44285 7.54717
424 2DT5 NAD 0.0008223 0.43891 7.58294
425 4RSL FAD 0.000001107 0.52313 7.64045
426 3CTY FAD 0.00000004365 0.53313 7.83699
427 1Q1R FAD 0.000006253 0.49275 7.88863
428 1XHC FAD 0.000005394 0.4985 7.90191
429 3BXO SAM 0.0275 0.40808 7.94979
430 3G89 SAM 0.0004165 0.4989 8.03213
431 4JK3 NAD 0.001302 0.43679 8.10811
432 2VDV SAM 0.002761 0.45802 8.13008
433 1WY7 SAH 0.01399 0.40419 8.21256
434 4D79 ATP 0.00003499 0.53467 8.33333
435 1R18 SAH 0.007806 0.41544 8.37004
436 1JG3 ADN 0.0002013 0.49912 8.51064
437 3ABI NAD 0.002826 0.41495 8.76712
438 4DCM SAM 0.01646 0.41586 8.8
439 1E5Q NDP 0.006562 0.4029 8.88889
440 5HRA DAS 0.02618 0.41256 8.93617
441 2XYQ SAH 0.01038 0.41894 9.01639
442 5BVA FAD 0.000002033 0.48059 9.04645
443 3MQ2 SAH 0.02566 0.40331 9.17431
444 4ZCC FAD 0.0000006759 0.47159 9.22619
445 4ZCC NAI 0.0000006759 0.47159 9.22619
446 1W2D ADP 0.04842 0.40202 9.43396
447 3EGV SAH 0.00576 0.43448 9.44882
448 2NXE SAM 0.006908 0.42725 9.44882
449 3QFA FAD 0.0000005518 0.5083 9.48276
450 1O8B ABF 0.03489 0.41326 9.58904
451 1MFI FHC 0.04672 0.40951 9.64912
452 1LLU NAD 0.003226 0.40333 9.64912
453 1GRN AF3 0.02509 0.42513 9.85222
454 2NPX FAD 0.00006814 0.45613 10.0671
455 2YVJ NAI 0.000005474 0.57234 10.0917
456 2YVJ FAD 0.00001058 0.48468 10.0917
457 3P2E SAH 0.01641 0.40381 10.2222
458 3RNM FAD 0.000000267 0.51327 10.3448
459 1RSG FAD 0.00000009992 0.53231 10.4651
460 1P1C SAH 0.0003559 0.47086 10.5528
461 3GCZ SAM 0.004973 0.43394 10.6383
462 1YY5 FAD 0.0000001313 0.51799 10.7212
463 1JQ3 AAT 0.001783 0.41522 10.8108
464 2XYA 7L4 0.007601 0.44546 10.989
465 4BV6 FAD 0.000003199 0.48786 11.1562
466 2BKX F6R 0.03453 0.40309 11.157
467 5FA8 SAM 0.01124 0.4057 11.1801
468 3KLJ FAD 0.00000126 0.53322 11.4286
469 1GG6 APL 0.009167 0.44668 11.4504
470 4YSX FAD 0.000001242 0.50663 11.5385
471 4C2W ANP 0.02208 0.42783 11.5385
472 3GD4 NAD 0.000379 0.46968 11.546
473 3GD4 FAD 0.00000879 0.42002 11.546
474 2WZM NA7 0.01104 0.41457 11.6608
475 3A4T SFG 0.0009874 0.45518 11.6788
476 1E6E FAD 0.000000201 0.54966 11.7188
477 4Z24 FAD 0.0000000000001339 0.72313 11.8421
478 2QGI UDP 0.03231 0.42115 12.0968
479 4DSU BZI 0.01878 0.43206 12.1693
480 2OOR NAD 0.000809 0.45901 12.6437
481 2OOR TXP 0.003006 0.41909 12.6437
482 1PNO NAP 0.002716 0.41563 12.7778
483 5ODQ FAD 0.000002215 0.48836 12.8571
484 3DUW SAH 0.001338 0.4567 13.0045
485 1E3W NAD 0.006522 0.40067 13.0268
486 3QV1 NAD 0.0004846 0.45788 13.4146
487 5J60 FAD 0.0000001033 0.54317 13.75
488 1KYQ NAD 0.0000205 0.55137 14.2336
489 4II2 ATP 0.00001931 0.5358 15.6627
490 1COY FAD 0.000000000001043 0.70324 16.1736
491 1COY AND 0.000000000003476 0.59258 16.1736
492 2DC1 NAD 0.007133 0.40384 16.5254
493 2FK8 SAM 0.003578 0.4337 16.9811
494 1TDF FAD 0.009079 0.4086 17.4051
495 1TDF NAP 0.02149 0.40782 17.4051
496 2GAG NAD 0.00000005789 0.56452 19.5238
497 2GAG FAD 0.000001068 0.4865 19.5238
498 2GAG FOA 0.000001676 0.48031 19.5238
499 1NAA 6FA 0.000000000000002331 0.76993 20.8647
500 1NAA ABL 0.000000000000009104 0.67655 20.8647
501 3QVP FAD 0.0000000000000594 0.72522 22.5564
502 4M38 SAH 0.003489 0.43419 23.8095
503 1N2X SAM 0.009835 0.40823 24.9169
504 2F5Z FAD 0.0000004246 0.52695 25
505 5FA5 MTA 0.001194 0.47153 25
506 1HE1 GDP 0.02261 0.40018 25
507 1LSS NAD 0.00001511 0.54059 28.5714
508 5L95 AMP 0.0001583 0.49924 36.25
509 4YNU FAD 0.000000000000001443 0.76677 40.2256
510 4YNU LGC 0.000000000000007216 0.70941 40.2256
511 5HSA FAS 0.0000000000007936 0.70676 40.2256
512 4HA6 FAD 0.00000000000001199 0.74733 41.3386
513 3Q9T FAY 0.00000006487 0.41098 43.0451
514 1GPE FAD 0.0000000000002464 0.68928 43.2331
Pocket No.: 2; Query (leader) PDB : 5EB4; Ligand: FAD; Similar sites found: 32
This union binding pocket(no: 2) in the query (biounit: 5eb4.bio2) has 42 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3BOF HCS 0.04562 0.41169 1.69173
2 2EJU SAH 0.01841 0.40813 1.85185
3 1CDO NAD 0.0104 0.40048 1.87166
4 1CT9 AMP 0.03445 0.41074 1.8797
5 1CT9 GLN 0.04905 0.40606 1.8797
6 1JAY NAP 0.01703 0.40129 1.88679
7 3IP8 B85 0.03632 0.40952 2.01613
8 1SQF SAM 0.01081 0.41906 2.0979
9 4IEE AGS 0.005988 0.45535 2.2449
10 3IP5 ALA 0.01057 0.44811 2.24719
11 1S20 TLA 0.03898 0.41059 2.94118
12 4K79 GAL A2G 0.02403 0.42291 3.18182
13 3KB6 NAD 0.005831 0.40838 3.29341
14 1YXM ADE 0.0264 0.4085 3.30033
15 5TDF 7A3 0.01954 0.40993 3.39506
16 2G2Y MLI 0.03459 0.40205 3.57143
17 4A2A ATP 0.02365 0.40017 3.57995
18 3F9W SAH 0.04721 0.40696 3.61446
19 1PZM 5GP 0.009758 0.44398 3.79147
20 5O4F 8VE 0.04908 0.40604 3.87597
21 4ISS TAR 0.02361 0.42289 3.94737
22 5KJW 53C 0.02974 0.41528 4.21546
23 1TE2 PGA 0.0498 0.4079 4.42478
24 1H5Q NAP 0.007651 0.4012 4.5283
25 3SWC SAH 0.03028 0.40071 4.91228
26 3TW1 AHN 0.02426 0.42825 5.48523
27 2YPI PGA 0.03769 0.40866 6.88259
28 3U4L ATP 0.01741 0.40355 9.28571
29 4URX HXY 0.02288 0.43019 15.6757
30 5J6H NCA 0.01501 0.40661 16
31 1YZG GDP 0.04719 0.40016 16.2011
32 5TH5 MET 0.04119 0.4154 16.73
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