Receptor
PDB id Resolution Class Description Source Keywords
5EV0 2.1 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF RAGWEED PROFILIN AMB A 8 IN COMPLEX WIT PRO14 AMBROSIA ARTEMISIIFOLIA ALLERGEN
Ref.: STRUCTURAL, FUNCTIONAL, AND IMMUNOLOGICAL CHARACTER OF PROFILIN PANALLERGENS AMB A 8, ART V 4, AND BET J.BIOL.CHEM. V. 291 15447 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PRO PRO PRO PRO PRO PRO PRO PRO PRO C:1;
D:1;
 Valid;
Valid;
 Atoms found LESS than expected: % Diff = 0.016;
Atoms found LESS than expected: % Diff = 0.016;
 submit data
877.077 n/a O=C(N...
MET A:133;
 Invalid;
 none;
 submit data
149.211 C5 H11 N O2 S CSCC[...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5EM1 1.45 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF RAGWEED ALLERGEN AMB A 8 AMBROSIA ARTEMISIIFOLIA ALLERGEN
Ref.: STRUCTURAL, FUNCTIONAL, AND IMMUNOLOGICAL CHARACTER OF PROFILIN PANALLERGENS AMB A 8, ART V 4, AND BET J.BIOL.CHEM. V. 291 15447 2016
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 5EM1 - BEZ C7 H6 O2 c1ccc(cc1)....
2 5EV0 - PRO PRO PRO PRO PRO PRO PRO PRO PRO n/a n/a
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 5EM1 - BEZ C7 H6 O2 c1ccc(cc1)....
2 5EV0 - PRO PRO PRO PRO PRO PRO PRO PRO PRO n/a n/a
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 5EM1 - BEZ C7 H6 O2 c1ccc(cc1)....
2 5EV0 - PRO PRO PRO PRO PRO PRO PRO PRO PRO n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: PRO PRO PRO PRO PRO PRO PRO PRO PRO; Similar ligands found: 12
Similar Ligands (3D)
Ligand no: 1; Ligand: PRO PRO PRO PRO PRO PRO PRO PRO PRO; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5EM1; Ligand: BEZ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 5em1.bio1) has 2 residues
No: Leader PDB Ligand Sequence Similarity
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