-->
Receptor
PDB id Resolution Class Description Source Keywords
5EYP 1.9 Å NON-ENZYME: OTHER TUBULIN-DARPIN COMPLEX OVIS ARIES DARPIN MICROTUBULE TUBULIN PROTEIN BINDING CELL CYCLE
Ref.: DESTABILIZING AN INTERACTING MOTIF STRENGTHENS THE ASSOCIATION OF A DESIGNED ANKYRIN REPEAT PROTEIN WI TUBULIN. SCI REP V. 6 28922 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL A:506;
B:505;
B:504;
A:507;
F:201;
F:202;
A:505;
F:203;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
MG A:502;
Invalid;
none;
submit data
24.305 Mg [Mg+2...
SO4 A:503;
B:503;
A:504;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
GDP B:501;
Valid;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
GTP A:501;
Valid;
none;
submit data
523.18 C10 H16 N5 O14 P3 c1nc2...
LOC B:502;
Valid;
none;
submit data
399.437 C22 H25 N O6 CC(=O...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5EYP 1.9 Å NON-ENZYME: OTHER TUBULIN-DARPIN COMPLEX OVIS ARIES DARPIN MICROTUBULE TUBULIN PROTEIN BINDING CELL CYCLE
Ref.: DESTABILIZING AN INTERACTING MOTIF STRENGTHENS THE ASSOCIATION OF A DESIGNED ANKYRIN REPEAT PROTEIN WI TUBULIN. SCI REP V. 6 28922 2016
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 4DRX - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
2 5EYP - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 4DRX - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
2 5EYP - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 5EYP - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 161
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 9GM 0.839506 0.973684
6 GNP 0.839506 0.973684
7 G 0.828947 0.986486
8 5GP 0.828947 0.986486
9 G1R 0.82716 0.986667
10 GCP 0.82716 0.973684
11 GSP 0.817073 0.948718
12 GAV 0.797619 0.961039
13 GMV 0.792683 0.973684
14 G2P 0.77381 0.961039
15 G2R 0.770115 0.961039
16 GP2 0.756098 0.961039
17 GDC 0.747253 0.961039
18 GKE 0.747253 0.961039
19 GDD 0.747253 0.961039
20 GPG 0.741573 0.961039
21 G3D 0.732558 0.986486
22 ALF 5GP 0.729412 0.888889
23 Y9Z 0.728261 0.902439
24 G5P 0.723404 0.973684
25 GFB 0.72043 0.961039
26 GTG 0.72043 0.936709
27 GDR 0.72043 0.961039
28 G4P 0.715909 0.986486
29 G3A 0.712766 0.973684
30 6CK 0.712766 0.936709
31 GDP AF3 0.7 0.888889
32 ALF GDP 0.7 0.888889
33 GDP ALF 0.7 0.888889
34 YGP 0.698925 0.901235
35 GKD 0.697917 0.961039
36 JB2 0.697917 0.961039
37 GDX 0.690722 0.973684
38 GPD 0.690722 0.925
39 GMP 0.684211 0.88
40 0O2 0.666667 0.986486
41 JB3 0.656863 0.948718
42 NGD 0.650485 0.961039
43 DGI 0.636364 0.923077
44 GDP 7MG 0.636364 0.911392
45 U2G 0.634615 0.936709
46 GPX 0.634409 0.946667
47 G G 0.632653 0.948052
48 IDP 0.632184 0.972973
49 2MD 0.632075 0.891566
50 CAG 0.62963 0.880952
51 CG2 0.622642 0.936709
52 FEG 0.619048 0.879518
53 MGD 0.614679 0.891566
54 ZGP 0.613208 0.869048
55 GH3 0.612903 0.973333
56 3GP 0.611765 0.946667
57 MD1 0.607143 0.891566
58 PGD 0.59292 0.925
59 DGT 0.591398 0.923077
60 BGO 0.588785 0.924051
61 TPG 0.582609 0.840909
62 DBG 0.582609 0.948718
63 2GP 0.574713 0.96
64 FE9 0.570175 0.776596
65 GCP G 0.56 0.921053
66 A G 0.553571 0.935065
67 G A A A 0.553571 0.923077
68 MGP 0.553191 0.961039
69 U A G G 0.548673 0.935065
70 G4M 0.548387 0.880952
71 6G0 0.547368 0.961039
72 G1R G1R 0.542373 0.924051
73 P2G 0.527473 0.883117
74 PGD O 0.525 0.850575
75 ADP 0.522222 0.92
76 R5I 0.520833 0.946667
77 R7I 0.520833 0.946667
78 GGM 0.517544 0.901235
79 DGP 0.516484 0.910256
80 DG 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G U 0.513274 0.9
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 AKW 0.504425 0.890244
86 G C 0.504348 0.9
87 GPC 0.491525 0.879518
88 G7M 0.483871 0.948052
89 6AD 0.479592 0.841463
90 ATP 0.473684 0.92
91 HEJ 0.473684 0.92
92 G2Q 0.471154 0.961039
93 5FA 0.46875 0.92
94 AQP 0.46875 0.92
95 GTA 0.468468 0.936709
96 7DD 0.468085 0.906667
97 G G G RPC 0.466102 0.875
98 SGP 0.463158 0.82716
99 01G 0.462963 0.902439
100 HFD 0.459184 0.873418
101 B4P 0.457447 0.894737
102 AP5 0.457447 0.894737
103 A2D 0.456522 0.894737
104 6YZ 0.455446 0.896104
105 G G G C 0.455285 0.9125
106 5GP 5GP 0.454545 0.883117
107 ANP 0.454545 0.896104
108 ACQ 0.454545 0.896104
109 AT4 0.452632 0.884615
110 A G C C 0.451613 0.911392
111 APC G U 0.45082 0.886076
112 PRT 0.449541 0.959459
113 G U34 0.449153 0.888889
114 DG DG 0.448598 0.865854
115 ITT 0.447917 0.868421
116 BA3 0.446809 0.894737
117 C2E 0.444444 0.921053
118 PCG 0.444444 0.933333
119 35G 0.444444 0.933333
120 MGO 0.441176 0.864198
121 AN2 0.4375 0.907895
122 G C C C 0.4375 0.924051
123 M33 0.43299 0.883117
124 UCG 0.429688 0.911392
125 A G U 0.42963 0.888889
126 ACP 0.428571 0.896104
127 MGQ 0.424528 0.935897
128 AR6 0.424242 0.894737
129 7DT 0.424242 0.906667
130 APR 0.424242 0.894737
131 93A 0.42268 0.833333
132 A4P 0.420168 0.869048
133 G8D 0.42 0.875
134 AD9 0.42 0.896104
135 SAP 0.42 0.873418
136 AGS 0.42 0.873418
137 CA0 0.418367 0.896104
138 ATF 0.417476 0.884615
139 AGO 0.414634 0.888889
140 A G U U 0.414286 0.888889
141 NIA 0.413043 0.82716
142 MGV 0.412844 0.890244
143 TAT 0.411765 0.884615
144 T99 0.411765 0.884615
145 ADQ 0.411215 0.871795
146 A1R 0.411215 0.839506
147 RGT 0.410714 0.909091
148 CGP 0.409836 0.86747
149 C1Z 0.409091 0.986486
150 A 0.408602 0.893333
151 AMP 0.408602 0.893333
152 UP5 0.40678 0.873418
153 AMZ 0.406593 0.918919
154 C2R 0.406593 0.906667
155 JBT 0.405882 0.778947
156 A22 0.40566 0.907895
157 25L 0.405405 0.907895
158 ADX 0.40404 0.809524
159 8OD 0.401961 0.946667
160 50T 0.4 0.883117
161 4TC 0.4 0.851852
Ligand no: 2; Ligand: GTP; Similar ligands found: 156
No: Ligand ECFP6 Tc MDL keys Tc
1 GTP 1 1
2 GP3 0.921053 0.973684
3 GDP 0.909091 1
4 GSP 0.853659 0.948718
5 GNH 0.82716 0.986667
6 G1R 0.819277 0.986667
7 GAV 0.811765 0.961039
8 9GM 0.809524 0.973684
9 GNP 0.809524 0.973684
10 GCP 0.797619 0.973684
11 5GP 0.797468 0.986486
12 G 0.797468 0.986486
13 GMV 0.764706 0.973684
14 G2R 0.764045 0.961039
15 G5P 0.755319 0.973684
16 GTG 0.752688 0.936709
17 G2P 0.747126 0.961039
18 G3A 0.744681 0.973684
19 GDD 0.741935 0.961039
20 GDC 0.741935 0.961039
21 GKE 0.741935 0.961039
22 0O2 0.736264 0.986486
23 GP2 0.729412 0.961039
24 6CK 0.726316 0.936709
25 Y9Z 0.723404 0.902439
26 GPG 0.717391 0.961039
27 GFB 0.715789 0.961039
28 GDR 0.715789 0.961039
29 GPD 0.704082 0.925
30 GKD 0.693878 0.961039
31 JB2 0.693878 0.961039
32 GDX 0.686869 0.973684
33 ALF 5GP 0.685393 0.888889
34 GH3 0.681319 0.973333
35 YGP 0.677083 0.901235
36 G3D 0.67033 0.986486
37 GDP AF3 0.659574 0.888889
38 ALF GDP 0.659574 0.888889
39 GDP ALF 0.659574 0.888889
40 DGT 0.659341 0.923077
41 GMP 0.658228 0.88
42 G4P 0.655914 0.986486
43 JB3 0.653846 0.948718
44 NGD 0.647619 0.961039
45 CAG 0.642202 0.880952
46 2MD 0.62963 0.891566
47 MGP 0.619565 0.961039
48 U2G 0.616822 0.936709
49 6G0 0.612903 0.961039
50 MGD 0.612613 0.891566
51 TPG 0.608696 0.840909
52 CG2 0.605505 0.936709
53 GDP 7MG 0.601942 0.911392
54 FEG 0.601852 0.879518
55 G G 0.598039 0.948052
56 ZGP 0.59633 0.869048
57 PGD 0.591304 0.925
58 MD1 0.591304 0.891566
59 3GP 0.590909 0.946667
60 GPX 0.581633 0.946667
61 DGI 0.580645 0.923077
62 IDP 0.576087 0.972973
63 DBG 0.567797 0.948718
64 2GP 0.555556 0.96
65 FE9 0.555556 0.776596
66 G4M 0.547619 0.880952
67 BGO 0.544643 0.924051
68 GCP G 0.543689 0.921053
69 ATP 0.537634 0.92
70 HEJ 0.537634 0.92
71 G1G 0.533898 0.925
72 AQP 0.531915 0.92
73 5FA 0.531915 0.92
74 A G 0.525862 0.935065
75 G A A A 0.525862 0.923077
76 U A G G 0.521368 0.935065
77 HFD 0.520833 0.873418
78 R5I 0.520408 0.946667
79 R7I 0.520408 0.946667
80 01G 0.518868 0.902439
81 P2G 0.510638 0.883117
82 ITT 0.510638 0.868421
83 AKW 0.504348 0.890244
84 GGM 0.504274 0.901235
85 G1R G1R 0.504065 0.924051
86 DGP 0.5 0.910256
87 PGD O 0.5 0.850575
88 MGO 0.5 0.864198
89 DG 0.5 0.910256
90 P1G 0.5 0.871795
91 GTA 0.495495 0.936709
92 PRT 0.490741 0.959459
93 B4P 0.489362 0.894737
94 AP5 0.489362 0.894737
95 IMP 0.489362 0.959459
96 G U 0.487179 0.9
97 7DT 0.484536 0.906667
98 GPC 0.479339 0.879518
99 G C 0.478992 0.9
100 BA3 0.478723 0.894737
101 ADP 0.473684 0.92
102 G2Q 0.471698 0.961039
103 6YZ 0.470588 0.896104
104 G7M 0.46875 0.948052
105 C1Z 0.462963 0.986486
106 25L 0.458716 0.907895
107 A2D 0.457447 0.894737
108 RGT 0.45045 0.909091
109 AGS 0.45 0.873418
110 SAP 0.45 0.873418
111 SGP 0.44898 0.82716
112 A4P 0.445378 0.869048
113 G G G RPC 0.442623 0.875
114 ANP 0.441176 0.896104
115 ACQ 0.441176 0.896104
116 8GT 0.441176 0.875
117 APC G U 0.44 0.886076
118 AT4 0.438776 0.884615
119 G U34 0.438017 0.888889
120 6AD 0.436893 0.841463
121 G G G C 0.433071 0.9125
122 UP5 0.432203 0.873418
123 PCG 0.431373 0.933333
124 C2E 0.431373 0.921053
125 35G 0.431373 0.933333
126 A G C C 0.429688 0.911392
127 T99 0.427184 0.884615
128 5GP 5GP 0.427184 0.883117
129 TAT 0.427184 0.884615
130 AR6 0.425743 0.894737
131 APR 0.425743 0.894737
132 7DD 0.424242 0.906667
133 AN2 0.424242 0.907895
134 DG DG 0.423423 0.865854
135 AD9 0.421569 0.896104
136 M33 0.42 0.883117
137 7D4 0.42 0.835443
138 UCG 0.419847 0.911392
139 HDV 0.419048 0.825
140 H6Y 0.419048 0.946667
141 G C C C 0.416667 0.924051
142 ACP 0.415842 0.896104
143 T5A 0.414634 0.802326
144 A1R 0.412844 0.839506
145 ADQ 0.412844 0.871795
146 MGQ 0.412844 0.935897
147 A3R 0.412844 0.839506
148 MGT 0.411215 0.823529
149 A G U 0.410072 0.888889
150 93A 0.41 0.833333
151 A22 0.407407 0.907895
152 CA0 0.405941 0.896104
153 ATF 0.40566 0.884615
154 AGO 0.404762 0.888889
155 MGV 0.401786 0.890244
156 CGP 0.4 0.86747
Ligand no: 3; Ligand: LOC; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 LOC 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5EYP; Ligand: GDP; Similar sites found with APoc: 159
This union binding pocket(no: 1) in the query (biounit: 5eyp.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
1 2ACV UDP 1.79775
2 5TE1 7A2 3.5503
3 3N9R TD3 3.5503
4 1RL4 BL5 3.7234
5 1EYQ NAR 4.05405
6 1W62 PYC 4.14201
7 5OLK DTP 4.14201
8 1P9B HDA 4.14201
9 3OCP CMP 4.31655
10 3QSB 743 4.49438
11 2RHO GSP 4.61538
12 2RHO GDP 4.61538
13 4EI7 GDP 4.62725
14 5Y02 HBX 4.6729
15 4BTV RB3 4.73373
16 1NX4 AKG 4.7619
17 1P77 ATR 4.77941
18 3E70 GDP 4.87805
19 1O5Q PYR 4.94382
20 4M52 FAD 5.09978
21 2B99 RDL 5.12821
22 1T9D P22 5.16854
23 2YIV NBN 5.18293
24 3KP6 SAL 5.29801
25 4WOE 3S5 5.32544
26 4TQK NAG 5.32544
27 2UXR ICT 5.47264
28 5NM7 GLY 5.6391
29 1UNH IXM 5.76923
30 2GWH PCI 5.8427
31 2I6U CP 5.8427
32 4UP4 NDG 5.91716
33 4UP4 NAG 5.91716
34 1NF8 BOG 5.91716
35 3B9Q MLI 6.29139
36 3BWN PMP 6.29213
37 2WD7 VGD 6.34328
38 2YVE MBT 6.48649
39 1Q19 SSC 6.50888
40 1O9P MLA 6.50888
41 5VEQ PMP 6.50888
42 5K8P 6R8 6.50888
43 3THR C2F 6.50888
44 3P9T TCL 6.50888
45 1PJS NAD 6.56455
46 3N8K D1X 6.65188
47 4MOP 2H5 6.74157
48 1W5F G2P 6.79887
49 6FLZ MMA 6.87361
50 5O22 C3R 6.92042
51 6BYF CIT 7.05882
52 1RQ2 CIT 7.06806
53 3TDC 0EU 7.10059
54 4A91 GLU 7.10059
55 3ITJ CIT 7.10059
56 3B8I OXL 7.10059
57 4GN8 ASO 7.10059
58 5LJW ANP 7.10059
59 6FP4 FAD 7.10059
60 6FP4 E1T 7.10059
61 2ZGY GDP 7.1875
62 4Y9D NAI 7.21311
63 1IXI 2HP 7.31707
64 4NPL AKG 7.6
65 3JYY PPV 7.86517
66 1YBH P22 7.86517
67 5V6F MAN BMA MAN 7.97101
68 4KJU 1RH 8.13953
69 4LAX FK5 8.17844
70 5HTX ADP 8.28402
71 6FXR UDP 8.31461
72 1TZD ADP 8.36364
73 5ZI9 FLC 8.46154
74 2P9H IPT 8.55019
75 2E2P ADP 8.87574
76 2HIM ASN 8.87574
77 2BQP GLC 8.97436
78 2GBB CIT 8.97436
79 3KOX Z98 9.09091
80 3AVR OGA 9.21348
81 5IFK HPA 9.61539
82 1WZ1 DNS 9.7561
83 2WT9 NIO 9.78723
84 5GVR LMR 9.82906
85 2IMG MLT 9.93377
86 4TVD BGC 9.97783
87 4LAY I63 10.0592
88 1J78 OLA 10.0592
89 2HQM FAD 10.0592
90 6ACS CIT 10.0775
91 1ECM TSA 10.0917
92 5HUA FK5 10.4348
93 2BOI MFU 10.6195
94 6DWI HD4 10.6509
95 2EFX NFA 10.6509
96 5OC1 FAD 10.6509
97 1VBO MAN MAN MAN 10.7383
98 2GMM MAN MAN 11.1111
99 1UKG MMA 11.1111
100 1Q8S MAN MMA 11.1111
101 1Q8Q MAN MMA 11.1111
102 1Q8V MAN MAN MAN 11.1111
103 1Q8O MAN MMA 11.1111
104 2PHX MAN MAN MAN MAN 11.1111
105 2PHF MAN MAN BMA MAN 11.1111
106 2PHT MAN MAN MAN BMA MAN 11.1111
107 2PHR MAN MAN BMA MAN 11.1111
108 2PHU MAN MAN MAN BMA MAN 11.1111
109 2PHW MAN MAN MAN BMA MAN MAN MAN 11.1111
110 2PHU MAN MAN 11.1111
111 2GNM MAN 11.1111
112 2GNB MAN 11.1111
113 1OFS SUC 11.2299
114 3V1S 0LH 11.2426
115 2JK0 ASP 11.2426
116 1BZL GCG 11.2426
117 2Z9I GLY ALA THR VAL 11.7284
118 3CYI ATP 11.8182
119 1OFZ FUC 11.8343
120 1OFZ FUL 11.8343
121 5TDC NMM ILE PHE SER 11.8421
122 4DXD GDP 11.9101
123 5XDT MB3 11.9101
124 5XDT GDP 11.9101
125 4JZR 4JR 12.037
126 1JXN MFU 12.426
127 2VAP GDP 12.9121
128 5EYY MDM 13.0178
129 3GDN HBX 13.0178
130 3GDN FAD 13.0178
131 3OF1 CMP 13.4146
132 1LOB MMA 13.4615
133 5W7B MYR 13.4752
134 4XTR ADP 13.5135
135 3CEV ARG 13.6095
136 1HE1 AF3 13.6364
137 3CM2 X23 13.8462
138 4P8O 883 14.2012
139 1XXR MAN 14.2857
140 3VGL ANP 14.3302
141 2R75 01G 14.7929
142 1OFU GDP 15
143 4D86 ADP 15.3846
144 1GDE GLU PLP 15.3846
145 4IJ6 SEP 15.3846
146 1JHG TRP 15.3846
147 1VKF CIT 15.3846
148 5CKS GAL 15.9763
149 5C8W PCG 16.7832
150 5TXR PLP 17.1598
151 4FFG 0U8 17.1598
152 4YRY FAD 17.1598
153 2IZ1 ATR 17.1598
154 3KC1 2T6 17.7515
155 6CI9 F3V 19.305
156 1V84 GAL NDG 19.7628
157 1PVS 7HP 20.922
158 5C1M OLC 21.6
159 1ZGS XMM 33.1361
Pocket No.: 2; Query (leader) PDB : 5EYP; Ligand: GTP; Similar sites found with APoc: 152
This union binding pocket(no: 2) in the query (biounit: 5eyp.bio1) has 28 residues
No: Leader PDB Ligand Sequence Similarity
1 4YZ5 DAN 2.95858
2 4RP9 ASC 3.44086
3 3B5J 12D 4.04494
4 2UVO NAG 4.09357
5 1W62 PYC 4.14201
6 4RKC PMP 4.27136
7 2RHO GSP 4.61538
8 2RHO GDP 4.61538
9 4EI7 GDP 4.62725
10 2XIB DFU 4.73373
11 4V15 PLP 4.74934
12 4WGF HX2 4.87805
13 4M00 SUC 4.94382
14 1O5Q PYR 4.94382
15 2FMD MAN MAN 5
16 5EXK MET 5.13595
17 3OEN GLU 5.24476
18 2WPB ZZI 5.26316
19 2WME NAP 5.32151
20 5FPE 3TR 5.32544
21 2FLI DX5 5.32544
22 4NAE 1GP 5.33333
23 4KFU ACP 5.66038
24 4CM8 IZ9 5.90278
25 1KJ8 GAR 5.91716
26 3C3D FO1 5.91716
27 3Q9T FAY 5.91716
28 3HSS MLA 5.91716
29 2R0H CTO 6.09756
30 2Q0L NAP 6.10932
31 1FQK ALF 6.12245
32 4IEE AGS 6.43016
33 1GPE FAD 6.50888
34 5VEQ PMP 6.50888
35 1PJS NAD 6.56455
36 1W5F G2P 6.79887
37 1QVJ RP5 6.84932
38 6FLZ MMA 6.87361
39 6BYF CIT 7.05882
40 1RQ2 CIT 7.06806
41 3K56 IS3 7.09534
42 4YNU FAD 7.10059
43 6APL C5P 7.10059
44 1MVQ MMA 7.10059
45 5LJW ANP 7.10059
46 2RAB FAD 7.10059
47 2RAB NAD 7.10059
48 2R4J 13P 7.10059
49 2R4J FAD 7.10059
50 3B8I OXL 7.10059
51 1IXI 2HP 7.31707
52 1D8C GLV 7.41573
53 1QXO EPS 7.47423
54 2A9G ARG 7.69231
55 5CX6 CDP 7.76053
56 4P6G 2FZ 7.9646
57 5V6F MAN BMA MAN 7.97101
58 1Q9I FAD 8.28402
59 1Q9I TEO 8.28402
60 1YTM OXD 8.28402
61 1WQ1 AF3 8.43373
62 3C7F XYP XYP XYP 8.87574
63 2HIM ASP 8.87574
64 4YKG NAD 8.87574
65 4YKG FAD 8.87574
66 2BQP GLC 8.97436
67 1GET FAD 9.46746
68 3HBN UDP 9.46746
69 1GET NAP 9.46746
70 1H5S TMP 9.55631
71 1H5R THM 9.55631
72 4EKQ NPO 9.62567
73 4TVD BGC 9.97783
74 1J78 OLA 10.0592
75 4HA6 FAD 10.0592
76 1PFK ADP 10.0592
77 3I7S PYR 10.0592
78 4YMU ATP 10.4167
79 3F8D FAD 10.6509
80 6DWI HD4 10.6509
81 5W8X UDP 10.6509
82 2EFX NFA 10.6509
83 3S5W NAP 10.6509
84 1VBO MAN 10.7383
85 1VBO MAN MAN MAN 10.7383
86 2GND MAN 11.1111
87 2PHU MAN MAN 11.1111
88 1Q8V MAN MAN 11.1111
89 2GNB MAN 11.1111
90 1UKG MMA 11.1111
91 1Q8O MAN MMA 11.1111
92 2PHT MAN MAN MAN 11.1111
93 2GN3 MAN 11.1111
94 2GMM MAN MAN 11.1111
95 2GND MAN MMA 11.1111
96 2PHF MAN MAN 11.1111
97 2PHR MAN MAN 11.1111
98 2PHW MAN MAN 11.1111
99 2GN3 MMA 11.1111
100 1Q8P MAN MMA 11.1111
101 2GNM MAN 11.1111
102 2PHX MAN MAN 11.1111
103 1Q8Q MAN MMA 11.1111
104 2PHR MAN MAN BMA MAN 11.1111
105 1Q8S MAN MMA 11.1111
106 2PHF MAN MAN BMA MAN 11.1111
107 2PHW MAN MAN MAN BMA MAN MAN MAN 11.1111
108 2PHT MAN MAN MAN BMA MAN 11.1111
109 2PHU MAN MAN MAN BMA MAN 11.1111
110 2GMP NAG MAN 11.1111
111 2PHX MAN MAN MAN MAN 11.1111
112 2AUY NAG MAN MMA 11.1111
113 2AR6 NAG MAN 11.1111
114 1Q8V MAN MAN MAN 11.1111
115 2AR6 NAG MAN MAN MAN NAG 11.1111
116 1OFS SUC 11.2299
117 2JK0 ASP 11.2426
118 4W9F 3JU 11.3402
119 4W9H 3JF 11.3402
120 5NVX 4YY 11.3402
121 1XX6 ADP 11.5183
122 3IHB GLU 11.8343
123 3K5I AIR 11.8343
124 4DXD GDP 11.9101
125 5XDT MB3 11.9101
126 5XDT GDP 11.9101
127 3N7S 3N7 12.1739
128 5T7I LAT NAG GAL 12.2581
129 1JXN MFU 12.426
130 2VAP GDP 12.9121
131 5EYY MDM 13.0178
132 3GDN HBX 13.0178
133 3GDN FAD 13.0178
134 1LES GLC FRU 13.4615
135 1LOB MMA 13.4615
136 1TDF NAP 13.6095
137 5MIT NAP 14.2012
138 5MIT FAD 14.2012
139 1XXR MAN 14.2857
140 2R75 01G 14.7929
141 1OFU GDP 15
142 4IJ6 SEP 15.3846
143 4B9K TG0 15.7895
144 4A59 AMP 15.9763
145 5TXR PLP 17.1598
146 2WDQ TEO 18.6047
147 1HBK COA 23.5955
148 5KZD RCJ 26.6272
149 1FQJ ALF 28.5714
150 2BOS GLA GAL GLC 29.4118
151 2BOS GLA GAL GLC NBU 29.4118
152 1ZGS XMM 33.1361
Pocket No.: 3; Query (leader) PDB : 5EYP; Ligand: LOC; Similar sites found with APoc: 106
This union binding pocket(no: 3) in the query (biounit: 5eyp.bio1) has 24 residues
No: Leader PDB Ligand Sequence Similarity
1 4WG0 CHD None
2 5HWV MBN 2.30769
3 2QK4 ATP 2.36686
4 4B1L FRU 3.0303
5 5TDF ADE 3.5503
6 4KBA 1QM 3.62538
7 4FGC PQ0 3.63636
8 5VKM GAL SIA 3.7037
9 1RL4 BL5 3.7234
10 5TPV TYD 3.92157
11 4MOB ADP 4.21687
12 1ELI PYC 4.62725
13 4YVN EBS 4.73373
14 3AI3 SOE 4.73373
15 1RYD GLC 4.73373
16 4GCZ FMN 4.73373
17 1A8U BEZ 4.73373
18 5OCG 9R5 4.7619
19 4WGF HX2 4.87805
20 3L5R 47X 4.91803
21 4FHD 0TT 5.16304
22 4FHD EEM 5.16304
23 3A70 NPO 5.16854
24 6FA4 D1W 5.20231
25 2WPB ZZI 5.26316
26 3KP6 SAL 5.29801
27 2PR5 FMN 5.30303
28 5EW9 5VC 5.32544
29 5BVE 4VG 5.54017
30 3CBC DBS 5.55556
31 3CV2 COA 5.61798
32 3WG3 A2G GAL NAG FUC 5.61798
33 5UI2 SUC 5.91716
34 3G5D 1N1 5.94406
35 2XG5 EC2 5.9633
36 2XG5 EC5 5.9633
37 1SDW IYT 6.05096
38 3BZ3 YAM 6.15942
39 5V3Y 5V8 6.29371
40 3DOO SKM 6.50888
41 1ME8 RVP 6.50888
42 1ZPD CIT 6.50888
43 1MID LAP 6.59341
44 5VNF VAL THR SER VAL VAL 7.00637
45 5A89 FMN 7.05128
46 2Z3U CRR 7.10059
47 2WKQ FMN 7.10059
48 1YFS ALA 7.31183
49 6GNO XDI 7.40741
50 5L2R MLA 7.64045
51 6EWZ APC 7.64045
52 3ZJX BOG 7.69231
53 1U25 IHS 7.69231
54 3A16 PXO 7.69231
55 1MJT ITU 8.06916
56 6E1Q CFA 8.28402
57 1Q8A HCS 8.28402
58 1GQG DCD 8.28402
59 2ART LPA AMP 8.39695
60 5UR1 YY9 8.68167
61 4ZVC BEZ 8.73016
62 4CJN QNZ 8.86918
63 4BE9 7P9 8.87574
64 3P7N FMN 8.91473
65 1F9V ADP 8.93372
66 3ITA AIC 9.09091
67 3T50 FMN 9.375
68 2XZ9 PYR 9.46746
69 1SQL GUN 9.58904
70 1A78 TDG 9.70149
71 6GSG RCO 9.92167
72 4L9I 8PR 10.0592
73 3BOF HCS 10.0592
74 3SAO DBH 10.625
75 2EFX NFA 10.6509
76 5KJW 53C 11.007
77 1C9K 5GP 11.1111
78 1T3D CYS 11.2426
79 1M3U KPL 11.4607
80 4WUJ FMN 11.5646
81 2Z6C FMN 11.6279
82 3ZO7 K6H 11.7021
83 1OFZ FUL 11.8343
84 1I7M PUT 11.9403
85 3E7S AT2 12.426
86 4RF7 ARG 12.5843
87 5OCM 9RH 13.0178
88 4X6F 3XU 13.3333
89 5W7B MYR 13.4752
90 5AIG VPR 13.6
91 2BD0 BIO 13.6095
92 5U98 1KX 14.1414
93 6AP8 BNY 14.4981
94 4P5Z Q7M 14.7929
95 5TVF CGQ 15.6923
96 1N9L FMN 16.5138
97 2BIF BOG 16.568
98 1X0P FAD 16.7832
99 1LNX URI 17.284
100 2Y69 CHD 17.5676
101 5Z84 CHD 19.1489
102 5ZCO CHD 19.1489
103 3H0L ADP 21.3018
104 5C1M OLC 21.6
105 1LSH PLD 23.3708
106 5CLO NS8 32.2034
APoc FAQ
Feedback