Receptor
PDB id Resolution Class Description Source Keywords
5FEP 1.45 Å EC: 7.-.-.- HYDE FROM T. MARITIMA IN COMPLEX WITH (2R,4R)-METDA THERMOTOGA MARITIMA RADICAL SAM ENZYME COMPLEX FEFE-HYDROGENASE MATURASE OXIDOREDUCTASE
Ref.: CARBON-SULFUR BOND-FORMING REACTION CATALYSED BY TH SAM ENZYME HYDE. NAT.CHEM. V. 8 491 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CPS A:404;
A:405;
A:406;
A:403;
A:402;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
 submit data
614.877 C32 H58 N2 O7 S C[C@H...
CL A:408;
 Invalid;
 none;
 submit data
35.453 Cl [Cl-]
SAM A:407;
 Valid;
 none;
 submit data
398.437 C15 H22 N6 O5 S C[S@@...
41K A:409;
 Valid;
 none;
 submit data
191.205 C6 H9 N O4 S C[C@]...
SF4 A:401;
 Part of Protein;
 none;
 submit data
351.64 Fe4 S4 [S]12...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4JYD 1.71 Å EC: 7.-.-.- X-RAY SNAPSHOTS OF POSSIBLE INTERMEDIATES IN THE TIME COURSE SYNTHESIS AND DEGRADATION OF PROTEIN-BOUND FE4S4 CLUSTERS. THERMOTOGA MARITIMA RADICAL SAM PROTEIN FEFE-HYDROGENASE ACTIVE SITE ASSEMBLY CLUSTER S-ADENOSYL-L-METHIONINE OXIDOREDUCTASE
Ref.: X-RAY SNAPSHOTS OF POSSIBLE INTERMEDIATES IN THE TI OF SYNTHESIS AND DEGRADATION OF PROTEIN-BOUND FE4S4 CLUSTERS. PROC.NATL.ACAD.SCI.USA V. 110 7188 2013
Members (18)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 319 families.
1 3CIW - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 4JYE - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 3CIX - SAH C14 H20 N6 O5 S c1nc(c2c(n....
4 5FEX - 5AD SEC n/a n/a
5 5FF3 - PRS C4 H7 N O2 S C1[C@H](NC....
6 5FEP - SAM C15 H22 N6 O5 S C[S@@+](CC....
7 3IIZ - SAM C15 H22 N6 O5 S C[S@@+](CC....
8 5FES - SAM C15 H22 N6 O5 S C[S@@+](CC....
9 5FF0 - 5X8 C13 H18 N6 O5 S c1nc(c2c(n....
10 4JXC - SAM C15 H22 N6 O5 S C[S@@+](CC....
11 4JY9 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
12 4JYF - SAH C14 H20 N6 O5 S c1nc(c2c(n....
13 5FF4 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
14 3IIX - MET C5 H11 N O2 S CSCC[C@@H]....
15 4JYD - SAH C14 H20 N6 O5 S c1nc(c2c(n....
16 5FEW - SAH C14 H20 N6 O5 S c1nc(c2c(n....
17 5FF2 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
18 5FEZ - 9SE C6 H9 N O4 Se C[C@]1(N[C....
70% Homology Family (18)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 271 families.
1 3CIW - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 4JYE - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 3CIX - SAH C14 H20 N6 O5 S c1nc(c2c(n....
4 5FEX - 5AD SEC n/a n/a
5 5FF3 - PRS C4 H7 N O2 S C1[C@H](NC....
6 5FEP - SAM C15 H22 N6 O5 S C[S@@+](CC....
7 3IIZ - SAM C15 H22 N6 O5 S C[S@@+](CC....
8 5FES - SAM C15 H22 N6 O5 S C[S@@+](CC....
9 5FF0 - 5X8 C13 H18 N6 O5 S c1nc(c2c(n....
10 4JXC - SAM C15 H22 N6 O5 S C[S@@+](CC....
11 4JY9 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
12 4JYF - SAH C14 H20 N6 O5 S c1nc(c2c(n....
13 5FF4 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
14 3IIX - MET C5 H11 N O2 S CSCC[C@@H]....
15 4JYD - SAH C14 H20 N6 O5 S c1nc(c2c(n....
16 5FEW - SAH C14 H20 N6 O5 S c1nc(c2c(n....
17 5FF2 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
18 5FEZ - 9SE C6 H9 N O4 Se C[C@]1(N[C....
50% Homology Family (18)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 223 families.
1 3CIW - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 4JYE - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 3CIX - SAH C14 H20 N6 O5 S c1nc(c2c(n....
4 5FEX - 5AD SEC n/a n/a
5 5FF3 - PRS C4 H7 N O2 S C1[C@H](NC....
6 5FEP - SAM C15 H22 N6 O5 S C[S@@+](CC....
7 3IIZ - SAM C15 H22 N6 O5 S C[S@@+](CC....
8 5FES - SAM C15 H22 N6 O5 S C[S@@+](CC....
9 5FF0 - 5X8 C13 H18 N6 O5 S c1nc(c2c(n....
10 4JXC - SAM C15 H22 N6 O5 S C[S@@+](CC....
11 4JY9 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
12 4JYF - SAH C14 H20 N6 O5 S c1nc(c2c(n....
13 5FF4 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
14 3IIX - MET C5 H11 N O2 S CSCC[C@@H]....
15 4JYD - SAH C14 H20 N6 O5 S c1nc(c2c(n....
16 5FEW - SAH C14 H20 N6 O5 S c1nc(c2c(n....
17 5FF2 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
18 5FEZ - 9SE C6 H9 N O4 Se C[C@]1(N[C....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: SAM; Similar ligands found: 246
No: Ligand ECFP6 Tc MDL keys Tc
1 SAM 1 1
2 SMM 0.792683 0.96
3 S4M 0.6875 0.909091
4 S7M 0.670455 0.945946
5 M2T 0.636364 0.878378
6 GEK 0.612903 0.931507
7 SAI 0.571429 0.878378
8 ADN 0.565789 0.773333
9 RAB 0.565789 0.773333
10 XYA 0.565789 0.773333
11 5CD 0.564103 0.783784
12 EP4 0.5625 0.826667
13 SA8 0.56044 0.945205
14 SFG 0.555556 0.875
15 5X8 0.555556 0.888889
16 5N5 0.551282 0.773333
17 A4D 0.544304 0.797297
18 EEM 0.542553 0.945946
19 SAH 0.537634 0.916667
20 EU9 0.537037 0.809524
21 DTA 0.536585 0.789474
22 62X 0.535354 0.884615
23 MTA 0.53012 0.875
24 3DH 0.517647 0.849315
25 AMP MG 0.517241 0.7375
26 5AL 0.510417 0.743902
27 VMS 0.510204 0.673913
28 54H 0.510204 0.673913
29 0UM 0.51 0.857143
30 NWW 0.506173 0.739726
31 LMS 0.505747 0.666667
32 AMP 0.505747 0.707317
33 A 0.505747 0.707317
34 45A 0.505618 0.753086
35 ABM 0.505618 0.753086
36 A5A 0.505155 0.688889
37 SSA 0.5 0.684783
38 5AD 0.5 0.75
39 SON 0.5 0.746988
40 6RE 0.5 0.78481
41 SRP 0.5 0.746988
42 K15 0.5 0.883117
43 LSS 0.49505 0.706522
44 CA0 0.494624 0.714286
45 AP2 0.494505 0.705882
46 A12 0.494505 0.705882
47 ME8 0.490385 0.841463
48 TSB 0.49 0.681319
49 5CA 0.49 0.684783
50 DAL AMP 0.49 0.765432
51 53H 0.49 0.666667
52 ACP 0.489362 0.694118
53 KG4 0.489362 0.714286
54 ADP 0.48913 0.690476
55 5AS 0.48913 0.648936
56 J7C 0.488889 0.772152
57 A2D 0.488889 0.690476
58 ZAS 0.488636 0.769231
59 8QN 0.485149 0.743902
60 9ZD 0.485149 0.729412
61 9ZA 0.485149 0.729412
62 8LH 0.484848 0.746988
63 GAP 0.484536 0.73494
64 AN2 0.483871 0.682353
65 A3S 0.483871 0.813333
66 ADP BEF 0.483871 0.728395
67 ADP MG 0.483871 0.728395
68 A7D 0.483871 0.851351
69 GJV 0.483516 0.775
70 SRA 0.483146 0.694118
71 GSU 0.480769 0.722222
72 KAA 0.480769 0.698925
73 LAD 0.480769 0.752941
74 DSZ 0.480392 0.703297
75 AMO 0.480392 0.746988
76 52H 0.48 0.666667
77 8LE 0.479592 0.717647
78 APC MG 0.479167 0.731707
79 M33 0.478723 0.722892
80 BA3 0.478261 0.690476
81 MAO 0.478261 0.82716
82 AOC 0.477778 0.776316
83 NEC 0.477778 0.75
84 DSH 0.477778 0.842105
85 SXZ 0.47619 0.894737
86 NVA LMS 0.475728 0.736264
87 AHX 0.475728 0.701149
88 Y3J 0.47561 0.706667
89 8LQ 0.475248 0.768293
90 QA7 0.475248 0.738095
91 G5A 0.474227 0.684783
92 A3T 0.473684 0.8
93 B4P 0.473118 0.690476
94 AP5 0.473118 0.690476
95 A3N 0.472527 0.766234
96 KB1 0.471698 0.833333
97 LEU LMS 0.471154 0.752809
98 PRX 0.46875 0.73494
99 APC 0.46875 0.705882
100 AT4 0.468085 0.686047
101 4AD 0.466019 0.759036
102 PAJ 0.466019 0.712644
103 NWQ 0.465909 0.767123
104 V2G 0.464646 0.701149
105 ATP MG 0.463918 0.728395
106 ADP PO3 0.463918 0.728395
107 ADV 0.463918 0.72619
108 RBY 0.463918 0.72619
109 ADX 0.463158 0.666667
110 MHZ 0.463158 0.82716
111 AU1 0.463158 0.674419
112 NB8 0.462264 0.72093
113 TXA 0.462264 0.72619
114 A3G 0.461538 0.802632
115 ANP MG 0.46 0.702381
116 VO4 ADP 0.46 0.694118
117 BEF ADP 0.459184 0.710843
118 VRT 0.459184 0.842105
119 XAH 0.458716 0.715909
120 KYE 0.458716 0.802469
121 YSA 0.458716 0.684783
122 50T 0.458333 0.682353
123 ATP 0.458333 0.690476
124 H1Q 0.458333 0.719512
125 HEJ 0.458333 0.690476
126 7D7 0.45679 0.723684
127 V47 0.455446 0.810811
128 KH3 0.455357 0.871795
129 ACQ 0.454545 0.694118
130 AR6 0.453608 0.710843
131 APR 0.453608 0.710843
132 5FA 0.453608 0.690476
133 AQP 0.453608 0.690476
134 NSS 0.451923 0.703297
135 FA5 0.449541 0.746988
136 AGS 0.44898 0.678161
137 A5D 0.44898 0.789474
138 AD9 0.44898 0.674419
139 PTJ 0.448598 0.72093
140 YLB 0.448276 0.758621
141 YLP 0.447368 0.738636
142 OZP 0.447368 0.844156
143 8X1 0.446602 0.680851
144 D3Y 0.446602 0.792208
145 N5O 0.445652 0.789474
146 ALF ADP 0.445545 0.678161
147 3AM 0.444444 0.674699
148 MYR AMP 0.444444 0.776471
149 HY8 0.443478 0.822785
150 OAD 0.443396 0.73494
151 2VA 0.443299 0.779221
152 KXW 0.442478 0.844156
153 QXP 0.442308 0.67033
154 S8M 0.442308 0.831169
155 OOB 0.442308 0.722892
156 6YZ 0.441176 0.694118
157 T99 0.44 0.686047
158 ANP 0.44 0.674419
159 TAT 0.44 0.686047
160 N37 0.439655 0.828947
161 WAQ 0.439252 0.75
162 HZ2 0.438596 0.822785
163 8PZ 0.436364 0.684783
164 B5Y 0.436364 0.717647
165 N5A 0.43617 0.786667
166 F0P 0.435897 0.844156
167 YLC 0.435897 0.755814
168 AAT 0.435644 0.797468
169 1ZZ 0.435185 0.755814
170 3OD 0.435185 0.73494
171 9K8 0.435185 0.663158
172 NVA 2AD 0.434343 0.855263
173 00A 0.433962 0.689655
174 DLL 0.433962 0.722892
175 7MD 0.433628 0.715909
176 ARG AMP 0.433628 0.727273
177 ATF 0.431373 0.666667
178 SO8 0.43 0.792208
179 A6D 0.429907 0.72619
180 QXG 0.429907 0.663043
181 9X8 0.429907 0.717647
182 3UK 0.429907 0.714286
183 F2R 0.429752 0.7
184 OZV 0.428571 0.690476
185 AMP DBH 0.428571 0.714286
186 5SV 0.428571 0.741176
187 TYM 0.42735 0.746988
188 WSA 0.42735 0.692308
189 9SN 0.427273 0.681818
190 AHZ 0.426087 0.755814
191 PR8 0.425926 0.744186
192 B5V 0.425926 0.705882
193 J4G 0.425926 0.759036
194 3NZ 0.425926 0.807692
195 P5A 0.425926 0.691489
196 R2V 0.425926 0.67033
197 A1R 0.424528 0.709302
198 2A5 0.424242 0.674419
199 Q34 0.423729 0.802469
200 7MC 0.423729 0.719101
201 Q2M 0.423729 0.846154
202 B5M 0.423423 0.717647
203 HQG 0.423077 0.702381
204 U4Y 0.422414 0.88
205 7D5 0.422222 0.658824
206 JB6 0.422018 0.709302
207 FYA 0.422018 0.722892
208 AYB 0.421488 0.75
209 JNT 0.420561 0.694118
210 K2H 0.420561 0.805195
211 B1U 0.419643 0.632653
212 MAP 0.419048 0.659091
213 KY2 0.419048 0.777778
214 A22 0.419048 0.682353
215 2AM 0.417582 0.666667
216 TAD 0.417391 0.712644
217 ADP BMA 0.416667 0.714286
218 A3P 0.416667 0.686747
219 25A 0.415094 0.690476
220 Q2V 0.413223 0.833333
221 YLA 0.413223 0.719101
222 K2K 0.412844 0.807692
223 8Q2 0.411765 0.663158
224 KYB 0.411215 0.777778
225 A3R 0.411215 0.709302
226 ADQ 0.411215 0.694118
227 KMQ 0.410714 0.72619
228 48N 0.410256 0.72093
229 0XU 0.41 0.824324
230 GA7 0.408696 0.72619
231 K3H 0.40708 0.775
232 7D3 0.40625 0.643678
233 PAP 0.405941 0.678571
234 DQV 0.405172 0.702381
235 OVE 0.404255 0.662791
236 4UV 0.403509 0.697674
237 ALF ADP 3PG 0.403361 0.712644
238 AF3 ADP 3PG 0.403361 0.712644
239 Q2P 0.403226 0.802469
240 3AD 0.402299 0.783784
241 2BA 0.402062 0.682927
242 CMP 0.402062 0.691358
243 K38 0.401786 0.7375
244 NAD TDB 0.4 0.731707
245 7C5 0.4 0.731707
246 NAD IBO 0.4 0.731707
Ligand no: 2; Ligand: 41K; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 41K 1 1
2 5ZZ 0.4 0.731707
Similar Ligands (3D)
Ligand no: 1; Ligand: SAM; Similar ligands found: 26
No: Ligand Similarity coefficient
1 TT8 0.9650
2 GDP 0.9145
3 8OD 0.9006
4 NWZ 0.8954
5 IDP 0.8910
6 CUU 0.8833
7 GNH 0.8826
8 KB7 0.8802
9 DTP 0.8779
10 GDP MG 0.8767
11 M7G 0.8755
12 G8D 0.8722
13 DZ4 0.8710
14 GTP 0.8703
15 DAT 0.8676
16 DGT 0.8665
17 GNP 0.8658
18 AV2 0.8650
19 HF7 0.8632
20 DGI 0.8627
21 HDV 0.8586
22 GCP 0.8586
23 TTP 0.8585
24 FZT 0.8567
25 GSP 0.8566
26 CTP 0.8538
Ligand no: 2; Ligand: 41K; Similar ligands found: 455
No: Ligand Similarity coefficient
1 9SE 0.9989
2 5XB 0.9676
3 APG 0.9498
4 GLU 0.9328
5 R9S 0.9320
6 3LR 0.9313
7 8GL 0.9309
8 2FT 0.9303
9 ALA ALA 0.9287
10 OGA 0.9252
11 7UC 0.9236
12 SYM 0.9234
13 GRO 0.9200
14 KDG 0.9195
15 ICB 0.9186
16 HIS 0.9180
17 FK8 0.9180
18 DAL DAL 0.9179
19 KMH 0.9179
20 DHS 0.9177
21 6JN 0.9175
22 0OC 0.9168
23 TRC 0.9163
24 GLN 0.9161
25 8EW 0.9158
26 AKG 0.9157
27 URQ 0.9151
28 SMN 0.9141
29 GGL 0.9135
30 DGL 0.9132
31 KDF 0.9129
32 9RW 0.9121
33 FOC 0.9109
34 2HG 0.9107
35 DZA 0.9100
36 XYH 0.9097
37 M5E 0.9095
38 OMD 0.9086
39 DGN 0.9081
40 TLA 0.9080
41 9ON 0.9079
42 CIT 0.9076
43 SKG 0.9072
44 40F 0.9067
45 HA7 0.9066
46 RAT 0.9064
47 TPO 0.9063
48 2IT 0.9061
49 PEQ 0.9056
50 173 0.9053
51 SOR 0.9049
52 3CR 0.9045
53 LFC 0.9045
54 K6H 0.9044
55 SEP 0.9044
56 PEP 0.9040
57 T9G 0.9037
58 XYS 0.9035
59 4HP 0.9030
60 152 0.9024
61 3HG 0.9024
62 MUC 0.9019
63 3PG 0.9016
64 091 0.9016
65 AL0 0.9014
66 PHE 0.9009
67 MTL 0.9007
68 N8P 0.9007
69 GCO 0.9005
70 DIR 0.8997
71 DGJ 0.8995
72 AHN 0.8995
73 GAE 0.8992
74 CUW 0.8992
75 GLR 0.8991
76 8OZ 0.8988
77 TSR 0.8987
78 92K 0.8983
79 DXG 0.8981
80 3BU 0.8979
81 GZQ 0.8978
82 AFS 0.8976
83 RNS 0.8975
84 6NT 0.8973
85 SD4 0.8972
86 TAR 0.8970
87 A29 0.8969
88 C5A 0.8967
89 FLC 0.8966
90 ZGL 0.8963
91 4TB 0.8961
92 RMN 0.8961
93 1L5 0.8957
94 GVM 0.8956
95 AOS 0.8956
96 HIO 0.8955
97 CS2 0.8950
98 TIU 0.8950
99 J0Z 0.8948
100 3NY 0.8948
101 FIX 0.8937
102 PD2 0.8937
103 PDC 0.8934
104 FUD 0.8933
105 GOJ 0.8932
106 HHH 0.8932
107 SOL 0.8931
108 ICT 0.8931
109 HQ9 0.8926
110 LLH 0.8922
111 OSE 0.8921
112 SRT 0.8917
113 XYL 0.8915
114 3SL 0.8913
115 CGB 0.8908
116 IXW 0.8906
117 ROR 0.8905
118 3YP 0.8905
119 XXP 0.8903
120 NCT 0.8903
121 LNR 0.8903
122 CAX 0.8902
123 K7M 0.8902
124 S7A 0.8902
125 S2P 0.8901
126 GLA 0.8901
127 61M 0.8900
128 9RH 0.8900
129 G8M 0.8899
130 NLG 0.8898
131 5FX 0.8898
132 4P0 0.8898
133 HL5 0.8897
134 DHI 0.8895
135 M6H 0.8895
136 DEW 0.8894
137 2ZM 0.8894
138 LPK 0.8894
139 GLO 0.8894
140 SDD 0.8891
141 5NI 0.8891
142 7C3 0.8891
143 23J 0.8890
144 449 0.8890
145 KTA 0.8888
146 XLS 0.8886
147 CXP 0.8884
148 DMV 0.8882
149 HL4 0.8878
150 EHM 0.8878
151 XUL 0.8878
152 S2G 0.8877
153 56D 0.8877
154 2AS 0.8877
155 KDO 0.8874
156 FA3 0.8874
157 AH8 0.8871
158 YZM 0.8868
159 51R 0.8867
160 LYS 0.8866
161 DII 0.8865
162 0HN 0.8865
163 GZ3 0.8865
164 PSJ 0.8863
165 2BX 0.8861
166 6NI 0.8861
167 1F1 0.8859
168 REL 0.8858
169 RBL 0.8858
170 PAC 0.8858
171 K6V 0.8855
172 7A3 0.8852
173 2AL 0.8852
174 GXL 0.8850
175 4PN 0.8850
176 9J3 0.8847
177 ACH 0.8846
178 DHY 0.8846
179 SYC 0.8844
180 AOT 0.8843
181 6M4 0.8843
182 HDL 0.8842
183 DYT 0.8840
184 4NC 0.8840
185 PFL 0.8839
186 FF3 0.8837
187 P58 0.8836
188 NCD 0.8834
189 JAW 0.8832
190 0HO 0.8832
191 5OB 0.8832
192 GCS 0.8832
193 HCI 0.8831
194 O45 0.8830
195 HBU 0.8829
196 PPY 0.8828
197 ONL 0.8827
198 MLT 0.8827
199 ODO 0.8825
200 GLY GLY 0.8824
201 LFR 0.8823
202 TYE 0.8823
203 MXN 0.8823
204 M44 0.8822
205 ABI 0.8822
206 DLY 0.8822
207 R2P 0.8820
208 Q07 0.8819
209 TCA 0.8819
210 GAL 0.8819
211 RUJ 0.8818
212 HYA 0.8818
213 PAF 0.8816
214 HNL 0.8815
215 SHI 0.8814
216 OAA 0.8814
217 SNE 0.8814
218 FEH 0.8811
219 HDH 0.8811
220 1SV 0.8811
221 BZ3 0.8810
222 HHI 0.8810
223 ORN 0.8810
224 3MF 0.8810
225 TYL 0.8809
226 4WK 0.8807
227 OOG 0.8806
228 3V4 0.8806
229 ICO 0.8805
230 149 0.8799
231 E4P 0.8798
232 2H5 0.8798
233 R67 0.8798
234 Q9Z 0.8797
235 TIH 0.8796
236 GLC 0.8795
237 OTR 0.8792
238 WOO 0.8792
239 GAF 0.8791
240 J9Q 0.8790
241 98J 0.8790
242 MR1 0.8788
243 GBN 0.8788
244 HG3 0.8788
245 TZM 0.8784
246 ASP 0.8784
247 I1E 0.8781
248 ARB 0.8781
249 5HY 0.8781
250 HNK 0.8780
251 RB0 0.8780
252 RB5 0.8780
253 IAC 0.8779
254 1AL 0.8776
255 RBJ 0.8771
256 X6X 0.8771
257 MES 0.8771
258 3S5 0.8768
259 15N 0.8768
260 FA1 0.8767
261 1BN 0.8767
262 PPR 0.8766
263 52C 0.8766
264 2HU 0.8765
265 X1R 0.8764
266 DOB 0.8764
267 HC4 0.8763
268 JDN 0.8762
269 1WC 0.8761
270 ASN 0.8761
271 N2Z 0.8760
272 Q06 0.8760
273 ASC 0.8758
274 MET 0.8758
275 0V5 0.8758
276 BMA 0.8757
277 PMF 0.8757
278 AEG 0.8757
279 BHU 0.8757
280 A3M 0.8756
281 OVM 0.8756
282 JF6 0.8755
283 AMQ 0.8755
284 3A9 0.8754
285 ICF 0.8752
286 Q03 0.8748
287 TAG 0.8747
288 QY9 0.8747
289 3QM 0.8746
290 SPV 0.8745
291 46P 0.8742
292 3C4 0.8740
293 N7P 0.8739
294 HZP 0.8739
295 GUA 0.8738
296 PC 0.8736
297 URO 0.8735
298 XRG 0.8735
299 I4B 0.8734
300 3MB 0.8734
301 G4D 0.8732
302 LX1 0.8731
303 SC2 0.8731
304 7WG 0.8731
305 NDH 0.8731
306 PIM 0.8730
307 3QO 0.8727
308 3AL 0.8727
309 6FZ 0.8727
310 S8V 0.8726
311 5RN 0.8726
312 OEM 0.8724
313 C2Y 0.8723
314 GVG 0.8723
315 MZT 0.8722
316 PHU 0.8721
317 NVU 0.8721
318 AT3 0.8720
319 RUY 0.8719
320 LMR 0.8719
321 ARW 0.8718
322 UN1 0.8718
323 HGA 0.8716
324 OW4 0.8714
325 0QW 0.8712
326 8G0 0.8711
327 LDP 0.8708
328 3OC 0.8707
329 BGC 0.8705
330 4AV 0.8705
331 7A2 0.8704
332 CFA 0.8704
333 E5X 0.8702
334 VNL 0.8701
335 FBM 0.8701
336 E0O 0.8700
337 5WZ 0.8698
338 0JD 0.8698
339 6LW 0.8697
340 ISZ 0.8696
341 MNP 0.8695
342 XX3 0.8695
343 MEQ 0.8692
344 CTS 0.8691
345 MEV 0.8690
346 B40 0.8690
347 HPP 0.8688
348 2PG 0.8687
349 QUS 0.8687
350 86L 0.8686
351 HFA 0.8685
352 NIZ 0.8684
353 HHA 0.8684
354 B85 0.8683
355 ARG 0.8682
356 OW7 0.8682
357 JB8 0.8680
358 BDF 0.8680
359 SHA 0.8678
360 HSO 0.8678
361 4RW 0.8678
362 AMH 0.8676
363 CLT 0.8674
364 BHO 0.8674
365 PSV 0.8674
366 13P 0.8672
367 MSR 0.8672
368 SKM 0.8671
369 IF7 0.8671
370 IVL 0.8670
371 PGH 0.8670
372 8U3 0.8669
373 5XC 0.8669
374 MNM 0.8668
375 DPN 0.8667
376 HHT 0.8665
377 K34 0.8664
378 BNL 0.8664
379 1X4 0.8664
380 PGA 0.8663
381 M4T 0.8661
382 BNF 0.8661
383 AHB 0.8660
384 4CS 0.8659
385 8WQ 0.8659
386 NLE 0.8659
387 GLF 0.8659
388 M74 0.8659
389 069 0.8658
390 TEO 0.8657
391 4M0 0.8654
392 G3P 0.8653
393 HPS 0.8653
394 3R9 0.8652
395 JRB 0.8651
396 4P5 0.8651
397 TSS 0.8648
398 7N0 0.8647
399 XDK 0.8647
400 M45 0.8646
401 GLY GLY GLY 0.8643
402 I2M 0.8642
403 5CU 0.8640
404 CWJ 0.8639
405 AG2 0.8639
406 DQA 0.8638
407 Q02 0.8637
408 F31 0.8637
409 6TZ 0.8634
410 FA0 0.8634
411 2UB 0.8633
412 MFU 0.8633
413 DNF 0.8630
414 EDR 0.8630
415 MAJ 0.8627
416 HNH 0.8626
417 ILE 0.8622
418 FOM 0.8620
419 DAS 0.8619
420 KOJ 0.8617
421 PH3 0.8616
422 264 0.8616
423 SF6 0.8613
424 B2Y 0.8613
425 URS 0.8613
426 IPB 0.8612
427 G3H 0.8607
428 L13 0.8606
429 BHA 0.8600
430 NYL 0.8597
431 ACA 0.8597
432 97T 0.8596
433 3PO 0.8594
434 0F9 0.8594
435 54Z 0.8593
436 OEG 0.8593
437 GWM 0.8589
438 NFA 0.8581
439 X1S 0.8580
440 SPA 0.8579
441 1SA 0.8574
442 EYV 0.8572
443 92P 0.8567
444 BRH 0.8565
445 4JT 0.8562
446 RP5 0.8562
447 LNO 0.8562
448 YRL 0.8560
449 NM2 0.8557
450 EOL 0.8549
451 94W 0.8547
452 AMG 0.8538
453 COI 0.8536
454 9FE 0.8525
455 NM3 0.8511
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4JYD; Ligand: SAH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4jyd.bio1) has 33 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback