Receptor
PDB id Resolution Class Description Source Keywords
5FK7 2.05 Å EC: 3.2.1.26 STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH NEOKESTOSE XANTHOPHYLLOMYCES DENDRORHOUS HYDROLASE AMINO ACID SEQUENCE CARBOHYDRATES CATALYSIS CADOMAIN CLONING DIMERIZATION QUATERNARY PICHIA PASTORISGLYCOSIDE HYDROLASES FUNGAL PROTEINS KINETICS MOLECULARMOLECULAR CONFORMATION PROTEIN CONFORMATION PROTEIN STRUCSECONDARY SUBSTRATE SPECIFICITY BETA-FRUCTOFURANOSIDASE INVERTASE PREBIOTICS NEOKESTOSE
Ref.: STRUCTURAL ANALYSIS OF BETA-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS REVEALS UNIQUE FEATUR THE CRUCIAL ROLE OF N-GLYCOSYLATION IN OLIGOMERIZAT ACTIVITY J.BIOL.CHEM. V. 291 6843 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NAG NAG BMA MAN MAN MAN B:1058;
A:1058;
Invalid;
Invalid;
none;
none;
submit data n/a n/a n/a n/a
NAG A:1555;
A:1644;
B:1471;
B:1644;
A:1125;
B:1215;
A:1512;
B:1052;
A:1319;
B:1555;
B:1319;
B:1483;
A:1483;
A:1606;
B:1242;
A:1471;
A:1236;
A:1215;
B:1357;
A:1357;
B:1539;
A:1539;
A:1052;
B:1444;
A:1242;
A:1444;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
221.208 C8 H15 N O6 CC(=O...
NAG NAG BMA MAN MAN MAN MAN MAN MAN B:1107;
A:1107;
Invalid;
Invalid;
none;
none;
submit data n/a n/a n/a n/a
NAG NAG A:1576;
B:1576;
Invalid;
Invalid;
none;
none;
submit data
408.404 n/a O=C(N...
GLC FRU FRU A:1001;
B:1001;
Valid;
Valid;
none;
none;
submit data
504.438 n/a O(C1(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5FMD 1.78 Å EC: 3.2.1.26 STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH NYSTOSE XANTHOPHYLLOMYCES DENDRORHOUS HYDROLASE CARBOHYDRATES CATALYSIS CATALYTIC DOMAIN CLONIDIMERIZATION QUATERNARY PICHIA PASTORIS GLYCOSIDE HYDROLFUNGAL PROTEINS KINETICS MOLECULAR CONFORMATION SUBSTRATSPECIFICITY INVERTASE PREBIOTICS NYSTOSE
Ref.: STRUCTURAL ANALYSIS OF BETA-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS REVEALS UNIQUE FEATUR THE CRUCIAL ROLE OF N-GLYCOSYLATION IN OLIGOMERIZAT ACTIVITY J.BIOL.CHEM. V. 291 6843 2016
Members (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 7 families.
1 5FK7 - GLC FRU FRU n/a n/a
2 5FMB - FRU C6 H12 O6 C([C@@H]1[....
3 5FKC - FRU GLC GLA n/a n/a
4 5FIX - SUC C12 H22 O11 C([C@@H]1[....
5 5FK8 - GLC GLC FRU n/a n/a
6 5FKB - GLC FRU FRU n/a n/a
7 5FMD - NYT C24 H42 O21 C([C@@H]1[....
8 5FMC - FRU C6 H12 O6 C([C@@H]1[....
70% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 7 families.
1 5FK7 - GLC FRU FRU n/a n/a
2 5FMB - FRU C6 H12 O6 C([C@@H]1[....
3 5FKC - FRU GLC GLA n/a n/a
4 5FIX - SUC C12 H22 O11 C([C@@H]1[....
5 5FK8 - GLC GLC FRU n/a n/a
6 5FKB - GLC FRU FRU n/a n/a
7 5FMD - NYT C24 H42 O21 C([C@@H]1[....
8 5FMC - FRU C6 H12 O6 C([C@@H]1[....
50% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 6 families.
1 5FK7 - GLC FRU FRU n/a n/a
2 5FMB - FRU C6 H12 O6 C([C@@H]1[....
3 5FKC - FRU GLC GLA n/a n/a
4 5FIX - SUC C12 H22 O11 C([C@@H]1[....
5 5FK8 - GLC GLC FRU n/a n/a
6 5FKB - GLC FRU FRU n/a n/a
7 5FMD - NYT C24 H42 O21 C([C@@H]1[....
8 5FMC - FRU C6 H12 O6 C([C@@H]1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GLC FRU FRU; Similar ligands found: 16
No: Ligand ECFP6 Tc MDL keys Tc
1 GLC FRU FRU 1 1
2 SWE 0.684211 0.972973
3 GLC FRU 0.684211 0.972973
4 SUC 0.684211 0.972973
5 FRU GLC GLA 0.651515 0.947368
6 RAF 0.651515 0.947368
7 GLC GLC FRU 0.597222 0.973684
8 DQR 0.567164 1
9 SUP 0.550725 0.782609
10 20S 0.544304 0.822222
11 NYT 0.527778 1
12 FNY 0.527778 1
13 LBS 0.52381 0.921053
14 0UB 0.5 0.921053
15 SUC GLA 0.455696 0.897436
16 FRU FRU 0.402985 0.921053
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5FMD; Ligand: NYT; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 5fmd.bio1) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 5FMD; Ligand: NYT; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 5fmd.bio2) has 26 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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