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Receptor
PDB id Resolution Class Description Source Keywords
5FK8 1.88 Å EC: 3.2.1.26 STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH NEO-ERLOSE XANTHOPHYLLOMYCES DENDRORHOUS HYDROLASE AMINO ACID SEQUENCE CARBOHYDRATES CATALYSIS CADOMAIN CLONING DIMERIZATION QUATERNARY PICHIA PASTORISGLYCOSIDE HYDROLASES FUNGAL PROTEINS KINETICS MOLECULARMOLECULAR CONFORMATION PROTEIN CONFORMATION PROTEIN STRUCSECONDARY SUBSTRATE SPECIFICITY BETA-FRUCTOFURANOSIDASE INVERTASE PREBIOTICS NEOERLOSE
Ref.: STRUCTURAL ANALYSIS OF BETA-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS REVEALS UNIQUE FEATUR THE CRUCIAL ROLE OF N-GLYCOSYLATION IN OLIGOMERIZAT ACTIVITY J.BIOL.CHEM. V. 291 6843 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NAG NAG BMA MAN MAN MAN B:1058;
Invalid;
none;
submit data n/a n/a n/a n/a
NAG A:1644;
A:1555;
B:1471;
B:1644;
A:1125;
B:1215;
A:1512;
B:1052;
A:1319;
B:1555;
B:1319;
A:1483;
B:1483;
A:1606;
B:1242;
A:1471;
A:1236;
B:1125;
A:1215;
B:1357;
A:1357;
B:1539;
A:1539;
A:1052;
B:1444;
A:1242;
A:1444;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
221.208 C8 H15 N O6 CC(=O...
NAG NAG BMA MAN MAN MAN MAN MAN MAN MAN A:1107;
B:1107;
Invalid;
Invalid;
none;
none;
submit data
1721.53 n/a O=C(N...
GLC GLC FRU B:1001;
A:1001;
Valid;
Valid;
none;
none;
submit data n/a n/a n/a n/a
NAG NAG A:1576;
B:1576;
Invalid;
Invalid;
none;
none;
submit data
408.404 n/a O=C(N...
NAG NAG BMA MAN MAN MAN MAN A:1058;
Invalid;
none;
submit data
1219.11 n/a O=C(N...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5FMD 1.78 Å EC: 3.2.1.26 STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH NYSTOSE XANTHOPHYLLOMYCES DENDRORHOUS HYDROLASE CARBOHYDRATES CATALYSIS CATALYTIC DOMAIN CLONIDIMERIZATION QUATERNARY PICHIA PASTORIS GLYCOSIDE HYDROLFUNGAL PROTEINS KINETICS MOLECULAR CONFORMATION SUBSTRATSPECIFICITY INVERTASE PREBIOTICS NYSTOSE
Ref.: STRUCTURAL ANALYSIS OF BETA-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS REVEALS UNIQUE FEATUR THE CRUCIAL ROLE OF N-GLYCOSYLATION IN OLIGOMERIZAT ACTIVITY J.BIOL.CHEM. V. 291 6843 2016
Members (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 5FK7 - GLC FRU FRU n/a n/a
2 5FMB - FRU C6 H12 O6 C([C@@H]1[....
3 5FKC - FRU GLC GLA n/a n/a
4 5FIX - SUC C12 H22 O11 C([C@@H]1[....
5 5FK8 - GLC GLC FRU n/a n/a
6 5FKB - GLC FRU FRU n/a n/a
7 5FMD - NYT C24 H42 O21 C([C@@H]1[....
8 5FMC - FRU C6 H12 O6 C([C@@H]1[....
70% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 5FK7 - GLC FRU FRU n/a n/a
2 5FMB - FRU C6 H12 O6 C([C@@H]1[....
3 5FKC - FRU GLC GLA n/a n/a
4 5FIX - SUC C12 H22 O11 C([C@@H]1[....
5 5FK8 - GLC GLC FRU n/a n/a
6 5FKB - GLC FRU FRU n/a n/a
7 5FMD - NYT C24 H42 O21 C([C@@H]1[....
8 5FMC - FRU C6 H12 O6 C([C@@H]1[....
50% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 5FK7 - GLC FRU FRU n/a n/a
2 5FMB - FRU C6 H12 O6 C([C@@H]1[....
3 5FKC - FRU GLC GLA n/a n/a
4 5FIX - SUC C12 H22 O11 C([C@@H]1[....
5 5FK8 - GLC GLC FRU n/a n/a
6 5FKB - GLC FRU FRU n/a n/a
7 5FMD - NYT C24 H42 O21 C([C@@H]1[....
8 5FMC - FRU C6 H12 O6 C([C@@H]1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GLC GLC FRU; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5FMD; Ligand: NYT; Similar sites found with APoc: 48
This union binding pocket(no: 1) in the query (biounit: 5fmd.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 6I6X H6B 1.43541
2 3B6O TMP 1.61943
3 5GLN XYP XYP XYP 1.74419
4 5GLN XYS 1.74419
5 4U6D 3DY 1.93237
6 4O8O AHR 2.08333
7 5AYE BMA BMA 2.08955
8 3UG4 AHR 2.38095
9 4K10 NI9 2.48619
10 5JOX EDG 2.51938
11 4D1J DGJ 2.77778
12 3JQ9 AX1 2.77778
13 5GNX BGC 2.78373
14 1W6F ISZ 2.8777
15 5Z5I XYS 2.94659
16 5Z5I FUB 2.94659
17 4N2R FUB 2.99401
18 4N2R AHR 2.99401
19 1AFS TES 3.09598
20 3TTY GLA 3.15789
21 4UDK NDG 3.45821
22 5ZQS BXP 3.51201
23 1PT2 SUC 3.80313
24 2Z9V PXM 3.82653
25 2YFT DQR 3.85289
26 3A72 AHR AHR 4.22535
27 1TZD ADP 4.36364
28 4C6H HE2 4.46735
29 2J73 GLC GLC GLC 4.85437
30 2J73 GLC GLC GLC GLC 4.85437
31 5M1Z 6LW AHR 5.17711
32 4AK7 47N 6.43564
33 4M8D 23J 6.46388
34 6A8H AHR AHR AHR 6.54206
35 2WDQ CBE 6.97674
36 5A7V MAN 7.2165
37 6F1J EDG 7.69231
38 3WUC GLC GAL 8.0292
39 4A34 FUL 8.16327
40 4J51 N75 8.28221
41 2GL0 ADN 8.38323
42 3IR1 MET 9.38776
43 1WKM MET 10.1695
44 3OYW TDG 11.9403
45 6GMN F4E 12.3711
46 2ADD SUC 12.8913
47 1Y9G FRU 16.6023
48 3LIH RAF 49.8423
Pocket No.: 2; Query (leader) PDB : 5FMD; Ligand: NYT; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 5fmd.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 5FMD; Ligand: NYT; Similar sites found with APoc: 16
This union binding pocket(no: 3) in the query (biounit: 5fmd.bio2) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 1WCQ DAN 1.16473
2 4UCF GLA 1.50376
3 4YHG CT3 1.79949
4 2YA8 G39 1.82556
5 2Q1A 2KT 2.04778
6 2BF6 SIA 3.11804
7 1S68 AMP 3.21285
8 3ZGJ RMN 3.2345
9 4D52 GXL 3.49206
10 4LED XXR 5.22388
11 4JIE BMA 5.5666
12 1S14 NOV 6.18557
13 5HSS 650 7.00809
14 3CQO FUC 8.19113
15 3GXA MET 8.36364
16 1EUS DAN 8.49315
Pocket No.: 4; Query (leader) PDB : 5FMD; Ligand: NYT; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 5fmd.bio2) has 26 residues
No: Leader PDB Ligand Sequence Similarity
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