Receptor
PDB id Resolution Class Description Source Keywords
5FKC 1.82 Å EC: 3.2.1.26 STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH RAFFINOSE XANTHOPHYLLOMYCES DENDRORHOUS HYDROLASE AMINO ACID SEQUENCE CARBOHYDRATES CATALYSIS CADOMAIN CLONING DIMERIZATION QUATERNARY PICHIA PASTORISGLYCOSIDE HYDROLASES FUNGAL PROTEINS KINETICS MOLECULARMOLECULAR CONFORMATION PROTEIN CONFORMATION PROTEIN STRUCSECONDARY SUBSTRATE SPECIFICITY BETA-FRUCTOFURANOSIDASE INVERTASE PREBIOTICS RAFFINOSE
Ref.: STRUCTURAL ANALYSIS OF BETA-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS REVEALS UNIQUE FEATUR THE CRUCIAL ROLE OF N-GLYCOSYLATION IN OLIGOMERIZAT ACTIVITY J.BIOL.CHEM. V. 291 6843 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NAG NAG BMA MAN MAN MAN G:1;
C:1;
 Invalid;
Invalid;
 none;
none;
 submit data
n/a n/a
NAG A:1644;
A:1555;
B:1471;
B:1644;
A:1125;
B:1215;
A:1512;
B:1052;
A:1319;
B:1555;
B:1319;
B:1483;
A:1483;
A:1606;
B:1242;
A:1471;
B:1125;
A:1236;
A:1215;
B:1357;
A:1357;
B:1539;
A:1539;
A:1052;
B:1444;
A:1242;
A:1444;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
 submit data
221.208 C8 H15 N O6 CC(=O...
NAG NAG BMA MAN MAN MAN MAN MAN MAN MAN D:1;
 Invalid;
 none;
 submit data
1721.53 n/a O=C(N...
NAG NAG I:1;
E:1;
 Invalid;
Invalid;
 none;
none;
 submit data
408.404 n/a O=C(N...
FRU GLC GLA F:1;
J:1;
 Valid;
Valid;
 none;
none;
 submit data
504.438 n/a O(CC1...
NAG NAG MAN BMA MAN MAN MAN MAN MAN MAN H:1;
 Invalid;
 none;
 submit data
n/a n/a
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5FMD 1.78 Å EC: 3.2.1.26 STRUCTURE OF D80A-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS COMPLEXED WITH NYSTOSE XANTHOPHYLLOMYCES DENDRORHOUS HYDROLASE CARBOHYDRATES CATALYSIS CATALYTIC DOMAIN CLONIDIMERIZATION QUATERNARY PICHIA PASTORIS GLYCOSIDE HYDROLFUNGAL PROTEINS KINETICS MOLECULAR CONFORMATION SUBSTRATSPECIFICITY INVERTASE PREBIOTICS NYSTOSE
Ref.: STRUCTURAL ANALYSIS OF BETA-FRUCTOFURANOSIDASE FROM XANTHOPHYLLOMYCES DENDRORHOUS REVEALS UNIQUE FEATUR THE CRUCIAL ROLE OF N-GLYCOSYLATION IN OLIGOMERIZAT ACTIVITY J.BIOL.CHEM. V. 291 6843 2016
Members (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 5FK7 - GLC FRU FRU n/a n/a
2 5FMB - FRU C6 H12 O6 C([C@@H]1[....
3 5FKC - FRU GLC GLA n/a n/a
4 5FIX - GLC FRU n/a n/a
5 5FK8 - GLC GLC FRU n/a n/a
6 5FKB - GLC FRU FRU n/a n/a
7 5FMD - GLC FRU FRU FRU n/a n/a
8 5FMC - FRU C6 H12 O6 C([C@@H]1[....
70% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 5FK7 - GLC FRU FRU n/a n/a
2 5FMB - FRU C6 H12 O6 C([C@@H]1[....
3 5FKC - FRU GLC GLA n/a n/a
4 5FIX - GLC FRU n/a n/a
5 5FK8 - GLC GLC FRU n/a n/a
6 5FKB - GLC FRU FRU n/a n/a
7 5FMD - GLC FRU FRU FRU n/a n/a
8 5FMC - FRU C6 H12 O6 C([C@@H]1[....
50% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 5FK7 - GLC FRU FRU n/a n/a
2 5FMB - FRU C6 H12 O6 C([C@@H]1[....
3 5FKC - FRU GLC GLA n/a n/a
4 5FIX - GLC FRU n/a n/a
5 5FK8 - GLC GLC FRU n/a n/a
6 5FKB - GLC FRU FRU n/a n/a
7 5FMD - GLC FRU FRU FRU n/a n/a
8 5FMC - FRU C6 H12 O6 C([C@@H]1[....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: FRU GLC GLA; Similar ligands found: 25
No: Ligand ECFP6 Tc MDL keys Tc
1 FRU GLC GLA 1 1
2 GLC FRU GLA GLA GLA 0.982456 1
3 GLC FRU GLA GLA 0.982456 1
4 GLC FRU GLA 0.710145 0.947368
5 GLC FRU FRU 0.651515 0.947368
6 Z9N GLC 0.537313 0.947368
7 MMA MAN 0.53125 0.846154
8 BGC GLC GLC GLC GLC GLC 0.523077 0.891892
9 BGC GLC GLC GLC GLC 0.523077 0.891892
10 GLC FRU 0.5 0.921053
11 ZEE UEA FRU FRU FRU 0.486842 0.947368
12 GLC FRU FRU FRU 0.486842 0.947368
13 BGC GLC GLC 0.472973 0.891892
14 BGC GLC GLC GLC 0.448718 0.891892
15 GLC GLC GLC GLC GLC 0.448718 0.891892
16 AHR AHR AHR AHR AHR AHR 0.439394 0.864865
17 AHR AHR AHR AHR 0.439394 0.864865
18 AHR AHR AHR AHR AHR 0.439394 0.864865
19 AHR AHR 0.4375 0.864865
20 GLC GLC GLC 0.435897 0.846154
21 BMA MAN MAN 0.426667 0.891892
22 BGC BGC BGC BGC 0.419753 0.891892
23 MMA MAN MAN 0.415584 0.846154
24 GLC GLC FRU 0.404762 0.973684
25 H1M MAN MAN 0.402439 0.785714
Similar Ligands (3D)
Ligand no: 1; Ligand: FRU GLC GLA; Similar ligands found: 1
No: Ligand Similarity coefficient
1 GLA GLC FRU 0.9325
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5FMD; Ligand: GLC FRU FRU FRU; Similar sites found with APoc: 2
This union binding pocket(no: 1) in the query (biounit: 5fmd.bio2) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 2ADD GLC FRU 12.8913
2 1Y9G FRU 16.6023
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