Receptor
PDB id Resolution Class Description Source Keywords
5FNQ 1.91 Å NON-ENZYME: OTHER STRUCTURE OF THE KEAP1 KELCH DOMAIN IN COMPLEX WITH A SMALL INHIBITOR. MUS MUSCULUS TRANSCRIPTION KEAP1 NRF2 OXIDATIVE STRESS
Ref.: MONO-ACIDIC INHIBITORS OF THE KELCH-LIKE ECH-ASSOCI PROTEIN 1 : NUCLEAR FACTOR ERYTHROID 2-RELATED FACT (KEAP1:NRF2) PROTEIN-PROTEIN INTERACTION WITH HIGH POTENCY IDENTIFIED BY FRAGMENT-BASED DISCOVERY. J.MED.CHEM. V. 59 3991 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
S0W A:1614;
 Valid;
 none;
 submit data
184.62 C9 H9 Cl O2 c1cc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5FNU 1.78 Å NON-ENZYME: OTHER STRUCTURE OF THE KEAP1 KELCH DOMAIN IN COMPLEX WITH A SMALL INHIBITOR. MUS MUSCULUS TRANSCRIPTION KEAP1 NRF2 OXIDATIVE STRESS
Ref.: MONO-ACIDIC INHIBITORS OF THE KELCH-LIKE ECH-ASSOCI PROTEIN 1 : NUCLEAR FACTOR ERYTHROID 2-RELATED FACT (KEAP1:NRF2) PROTEIN-PROTEIN INTERACTION WITH HIGH POTENCY IDENTIFIED BY FRAGMENT-BASED DISCOVERY. J.MED.CHEM. V. 59 3991 2016
Members (29)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 6T7Z ic50 = 55 nM ACY MV5 ASA 4FB GLU THR GLY GLU n/a n/a
2 5FNT Kd = 0.67 uM 0PL C24 H23 Cl N4 O4 S Cn1c2ccc(c....
3 4L7C ic50 = 7.4 uM 1VW C26 H26 N6 O3 c1ccc2c(c1....
4 5FNU Kd = 0.0013 uM L6I C28 H30 N4 O6 S Cc1ccc(cc1....
5 7C60 Kd = 27 nM NF3 C6 H8 O4 CCOC(=O)/C....
6 4ZY3 - K67 C29 H30 N2 O7 S2 CCOc1ccc(c....
7 7C5E Kd = 8.4 nM FUM C4 H4 O4 C(=C/C(=O)....
8 5FZJ - 75K C8 H7 N O3 Cc1nc2c(o1....
9 6Z6A Kd = 3.7 uM Q9E C23 H30 N4 O6 S CC(=O)N1CC....
10 3ZGC - GLY ASP GLU GLU THR GLY GLU n/a n/a
11 5FNR Kd = 59 uM XMS C16 H14 Cl N3 O2 Cn1c2ccc(c....
12 6QMC - J6H C14 H12 Cl N O3 c1cc(ccc1[....
13 5FNS Kd = 4 uM XYY C19 H21 Cl N4 O4 S Cn1c2ccc(c....
14 1X2R Ka = 5510000 M^-1 LEU ASP GLU GLU THR GLY GLU PHE LEU n/a n/a
15 6QMD ic50 = 170 uM J6N C16 H14 Cl N3 O2 Cn1c2ccc(c....
16 6LRZ Kd = 10 nM EOU C6 H8 O4 COC(=O)/C=....
17 6UF0 ic50 = 230 nM Q5Y C26 H24 N2 O8 S2 COc1ccc(cc....
18 6V6Z ic50 = 63 nM Q5Y C26 H24 N2 O8 S2 COc1ccc(cc....
19 5FNQ - S0W C9 H9 Cl O2 c1cc(ccc1C....
20 6TYP Kd = 2.7 nM PKG C28 H28 N4 O3 CCn1c2ccc(....
21 6QME ic50 = 44 uM J6Q C17 H16 Cl N3 O2 Cc1cc(ccc1....
22 4L7D ic50 = 0.75 uM 1VX C27 H30 N2 O4 Cc1cccc2c1....
23 6TYM Kd = 13.5 nM 08A C29 H30 N4 O3 CCn1c2ccc(....
24 5FZN - FB2 C6 H7 N O2 S c1ccc(cc1)....
25 5X54 Kd = 10 uM ACE GLU TRP TRP TRP n/a n/a
26 6QMJ ic50 = 0.069 uM J6K C26 H28 N4 O5 S Cc1ccc(cc1....
27 4L7B ic50 = 2.3 uM 1VV C26 H26 N2 O5 c1ccc2c(c1....
28 4IQK ic50 = 2.7 uM IQK C24 H22 N2 O6 S2 COc1ccc(cc....
29 4XMB Kd = 44 nM 41P C28 H28 N4 O8 S2 COc1ccc(cc....
70% Homology Family (31)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 6T7Z ic50 = 55 nM ACY MV5 ASA 4FB GLU THR GLY GLU n/a n/a
2 5FNT Kd = 0.67 uM 0PL C24 H23 Cl N4 O4 S Cn1c2ccc(c....
3 4L7C ic50 = 7.4 uM 1VW C26 H26 N6 O3 c1ccc2c(c1....
4 5FNU Kd = 0.0013 uM L6I C28 H30 N4 O6 S Cc1ccc(cc1....
5 7C60 Kd = 27 nM NF3 C6 H8 O4 CCOC(=O)/C....
6 4ZY3 - K67 C29 H30 N2 O7 S2 CCOc1ccc(c....
7 7C5E Kd = 8.4 nM FUM C4 H4 O4 C(=C/C(=O)....
8 5FZJ - 75K C8 H7 N O3 Cc1nc2c(o1....
9 6Z6A Kd = 3.7 uM Q9E C23 H30 N4 O6 S CC(=O)N1CC....
10 3ZGC - GLY ASP GLU GLU THR GLY GLU n/a n/a
11 5FNR Kd = 59 uM XMS C16 H14 Cl N3 O2 Cn1c2ccc(c....
12 6QMC - J6H C14 H12 Cl N O3 c1cc(ccc1[....
13 5FNS Kd = 4 uM XYY C19 H21 Cl N4 O4 S Cn1c2ccc(c....
14 1X2R Ka = 5510000 M^-1 LEU ASP GLU GLU THR GLY GLU PHE LEU n/a n/a
15 6QMD ic50 = 170 uM J6N C16 H14 Cl N3 O2 Cn1c2ccc(c....
16 6LRZ Kd = 10 nM EOU C6 H8 O4 COC(=O)/C=....
17 6UF0 ic50 = 230 nM Q5Y C26 H24 N2 O8 S2 COc1ccc(cc....
18 6V6Z ic50 = 63 nM Q5Y C26 H24 N2 O8 S2 COc1ccc(cc....
19 5FNQ - S0W C9 H9 Cl O2 c1cc(ccc1C....
20 6TYP Kd = 2.7 nM PKG C28 H28 N4 O3 CCn1c2ccc(....
21 6QME ic50 = 44 uM J6Q C17 H16 Cl N3 O2 Cc1cc(ccc1....
22 4L7D ic50 = 0.75 uM 1VX C27 H30 N2 O4 Cc1cccc2c1....
23 6TYM Kd = 13.5 nM 08A C29 H30 N4 O3 CCn1c2ccc(....
24 5FZN - FB2 C6 H7 N O2 S c1ccc(cc1)....
25 5X54 Kd = 10 uM ACE GLU TRP TRP TRP n/a n/a
26 6QMJ ic50 = 0.069 uM J6K C26 H28 N4 O5 S Cc1ccc(cc1....
27 4L7B ic50 = 2.3 uM 1VV C26 H26 N2 O5 c1ccc2c(c1....
28 4IQK ic50 = 2.7 uM IQK C24 H22 N2 O6 S2 COc1ccc(cc....
29 4XMB Kd = 44 nM 41P C28 H28 N4 O8 S2 COc1ccc(cc....
30 6QMK ic50 = 0.047 uM J8H C27 H28 N4 O6 S Cc1ccc(cc1....
31 6FMQ - ACE DYW GLU THR GLY GLU LEU n/a n/a
50% Homology Family (31)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 6T7Z ic50 = 55 nM ACY MV5 ASA 4FB GLU THR GLY GLU n/a n/a
2 5FNT Kd = 0.67 uM 0PL C24 H23 Cl N4 O4 S Cn1c2ccc(c....
3 4L7C ic50 = 7.4 uM 1VW C26 H26 N6 O3 c1ccc2c(c1....
4 5FNU Kd = 0.0013 uM L6I C28 H30 N4 O6 S Cc1ccc(cc1....
5 7C60 Kd = 27 nM NF3 C6 H8 O4 CCOC(=O)/C....
6 4ZY3 - K67 C29 H30 N2 O7 S2 CCOc1ccc(c....
7 7C5E Kd = 8.4 nM FUM C4 H4 O4 C(=C/C(=O)....
8 5FZJ - 75K C8 H7 N O3 Cc1nc2c(o1....
9 6Z6A Kd = 3.7 uM Q9E C23 H30 N4 O6 S CC(=O)N1CC....
10 3ZGC - GLY ASP GLU GLU THR GLY GLU n/a n/a
11 5FNR Kd = 59 uM XMS C16 H14 Cl N3 O2 Cn1c2ccc(c....
12 6QMC - J6H C14 H12 Cl N O3 c1cc(ccc1[....
13 5FNS Kd = 4 uM XYY C19 H21 Cl N4 O4 S Cn1c2ccc(c....
14 1X2R Ka = 5510000 M^-1 LEU ASP GLU GLU THR GLY GLU PHE LEU n/a n/a
15 6QMD ic50 = 170 uM J6N C16 H14 Cl N3 O2 Cn1c2ccc(c....
16 6LRZ Kd = 10 nM EOU C6 H8 O4 COC(=O)/C=....
17 6UF0 ic50 = 230 nM Q5Y C26 H24 N2 O8 S2 COc1ccc(cc....
18 6V6Z ic50 = 63 nM Q5Y C26 H24 N2 O8 S2 COc1ccc(cc....
19 5FNQ - S0W C9 H9 Cl O2 c1cc(ccc1C....
20 6TYP Kd = 2.7 nM PKG C28 H28 N4 O3 CCn1c2ccc(....
21 6QME ic50 = 44 uM J6Q C17 H16 Cl N3 O2 Cc1cc(ccc1....
22 4L7D ic50 = 0.75 uM 1VX C27 H30 N2 O4 Cc1cccc2c1....
23 6TYM Kd = 13.5 nM 08A C29 H30 N4 O3 CCn1c2ccc(....
24 5FZN - FB2 C6 H7 N O2 S c1ccc(cc1)....
25 5X54 Kd = 10 uM ACE GLU TRP TRP TRP n/a n/a
26 6QMJ ic50 = 0.069 uM J6K C26 H28 N4 O5 S Cc1ccc(cc1....
27 4L7B ic50 = 2.3 uM 1VV C26 H26 N2 O5 c1ccc2c(c1....
28 4IQK ic50 = 2.7 uM IQK C24 H22 N2 O6 S2 COc1ccc(cc....
29 4XMB Kd = 44 nM 41P C28 H28 N4 O8 S2 COc1ccc(cc....
30 6QMK ic50 = 0.047 uM J8H C27 H28 N4 O6 S Cc1ccc(cc1....
31 6FMQ - ACE DYW GLU THR GLY GLU LEU n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: S0W; Similar ligands found: 8
No: Ligand ECFP6 Tc MDL keys Tc
1 S0W 1 1
2 HPP 0.571429 0.64
3 PPT 0.555556 0.714286
4 HCI 0.527778 0.7
5 P47 0.5 0.653846
6 LSQ 0.47619 1
7 31S 0.421053 0.62963
8 4YZ 0.418605 0.8
Similar Ligands (3D)
Ligand no: 1; Ligand: S0W; Similar ligands found: 481
No: Ligand Similarity coefficient
1 HC4 1.0000
2 P81 0.9964
3 AHC 0.9836
4 F90 0.9780
5 BPW 0.9752
6 TYR 0.9661
7 YPN 0.9650
8 5OO 0.9647
9 6ZX 0.9627
10 TCA 0.9618
11 DTY 0.9615
12 ISA 0.9558
13 ENO 0.9528
14 PHI 0.9524
15 LVD 0.9524
16 DHC 0.9519
17 2UB 0.9516
18 TYC 0.9513
19 CFA 0.9512
20 QH3 0.9497
21 GB5 0.9496
22 TYE 0.9489
23 XIZ 0.9484
24 PBA 0.9441
25 GVY 0.9439
26 3ZB 0.9434
27 PO6 0.9424
28 0A1 0.9418
29 5LA 0.9398
30 HXY 0.9395
31 RQD 0.9395
32 4BF 0.9394
33 5O6 0.9392
34 PFF 0.9386
35 QIV 0.9385
36 NFA 0.9363
37 HHH 0.9357
38 IYR 0.9354
39 PHE 0.9351
40 F06 0.9350
41 SBK 0.9346
42 GB4 0.9339
43 HFA 0.9336
44 XCG 0.9330
45 UNJ 0.9322
46 OHJ 0.9322
47 4BY 0.9317
48 DAH 0.9315
49 PRA 0.9315
50 QBM 0.9313
51 F52 0.9311
52 4HP 0.9310
53 FK8 0.9310
54 2HC 0.9309
55 N9J 0.9304
56 PPY 0.9297
57 JAH 0.9290
58 36M 0.9285
59 N4B 0.9279
60 A5E 0.9279
61 TMG 0.9278
62 B3U 0.9276
63 4CF 0.9273
64 HIS 0.9273
65 Y3L 0.9270
66 P80 0.9264
67 36Y 0.9264
68 MMS 0.9258
69 ICB 0.9254
70 LT1 0.9254
71 YF3 0.9254
72 YOF 0.9251
73 P7Y 0.9247
74 2FX 0.9247
75 HF2 0.9246
76 TYL 0.9240
77 6SD 0.9235
78 1L5 0.9234
79 MP5 0.9234
80 MES 0.9225
81 PH3 0.9224
82 CXP 0.9218
83 DPN 0.9218
84 NFM 0.9217
85 RBJ 0.9216
86 92G 0.9215
87 6KT 0.9214
88 AKG 0.9213
89 264 0.9212
90 DHY 0.9209
91 4FE 0.9208
92 J6W 0.9206
93 J4K 0.9200
94 3H2 0.9198
95 363 0.9193
96 ALE 0.9188
97 C82 0.9181
98 Q9Z 0.9179
99 ESX 0.9178
100 GT4 0.9172
101 BNF 0.9167
102 JBZ 0.9165
103 YZM 0.9162
104 GWM 0.9161
105 K82 0.9157
106 IPO 0.9157
107 TB8 0.9154
108 M6H 0.9154
109 PBN 0.9148
110 CPZ 0.9146
111 MSR 0.9140
112 4BX 0.9139
113 I2E 0.9137
114 PLP 0.9129
115 S24 0.9129
116 268 0.9123
117 JA5 0.9121
118 FUD 0.9119
119 HWD 0.9108
120 HDH 0.9107
121 EYJ 0.9106
122 2QC 0.9104
123 ZEC 0.9104
124 3VS 0.9096
125 EQW 0.9095
126 AEF 0.9094
127 R9J 0.9093
128 SOJ 0.9093
129 61M 0.9091
130 3C4 0.9088
131 4LW 0.9086
132 ESP 0.9083
133 4LV 0.9081
134 4FP 0.9071
135 GO2 0.9071
136 J0Z 0.9067
137 5RP 0.9065
138 YRL 0.9064
139 BZ2 0.9064
140 258 0.9062
141 ARG 0.9061
142 PLR 0.9057
143 4FA 0.9054
144 IOP 0.9050
145 R52 0.9042
146 R5P 0.9042
147 HL4 0.9038
148 URO 0.9034
149 B40 0.9028
150 RES 0.9027
151 5WZ 0.9026
152 HIC 0.9026
153 4ZD 0.9024
154 AEG 0.9020
155 1F1 0.9019
156 X48 0.9013
157 BRH 0.9010
158 428 0.9010
159 FER 0.9009
160 OOG 0.9007
161 B41 0.9006
162 4I8 0.9004
163 PLP PMP 0.9000
164 GJK 0.8998
165 2LT 0.8997
166 42J 0.8994
167 A7H 0.8993
168 RCV 0.8992
169 LO1 0.8991
170 0A9 0.8990
171 M5E 0.8988
172 5SP 0.8985
173 FZM 0.8984
174 RP3 0.8984
175 650 0.8983
176 9BF 0.8979
177 YIE 0.8978
178 ENW 0.8976
179 KTW 0.8976
180 GLN 0.8972
181 SNU 0.8972
182 SOR 0.8969
183 1PS 0.8968
184 K7M 0.8968
185 E0O 0.8966
186 LDP 0.8966
187 SWX 0.8965
188 EVF 0.8965
189 E4P 0.8964
190 4WL 0.8963
191 OTR 0.8961
192 33S 0.8960
193 HX4 0.8957
194 657 0.8955
195 GCO 0.8955
196 8U3 0.8954
197 S7G 0.8954
198 3YP 0.8954
199 VC3 0.8953
200 7BC 0.8952
201 C1M 0.8951
202 263 0.8949
203 NYL 0.8945
204 GGB 0.8944
205 4AF 0.8942
206 PTU 0.8942
207 M74 0.8938
208 S8V 0.8937
209 2C0 0.8937
210 E3X 0.8935
211 OGA 0.8933
212 5TO 0.8932
213 4BL 0.8932
214 6FZ 0.8930
215 H4E 0.8928
216 BVS 0.8926
217 B1J 0.8925
218 80G 0.8923
219 ABF 0.8922
220 F4K 0.8922
221 B85 0.8920
222 FOM 0.8917
223 CS2 0.8916
224 SSB 0.8915
225 OLU 0.8915
226 F4E 0.8914
227 YI6 0.8913
228 AMR 0.8912
229 Y4L 0.8911
230 FWD 0.8909
231 1BN 0.8907
232 M1T 0.8906
233 8NB 0.8906
234 EUE 0.8905
235 DHI 0.8905
236 DYT 0.8904
237 56D 0.8903
238 AAN 0.8903
239 NAG 0.8903
240 S0D 0.8902
241 N91 0.8902
242 6J5 0.8901
243 3VW 0.8898
244 OQC 0.8898
245 HHI 0.8897
246 4TB 0.8895
247 TOH 0.8894
248 TZM 0.8892
249 6N4 0.8891
250 PNP 0.8890
251 RA7 0.8890
252 GVA 0.8889
253 EUH 0.8887
254 9VQ 0.8886
255 27K 0.8885
256 QME 0.8885
257 11C 0.8883
258 S2P 0.8883
259 MPV 0.8879
260 IWD 0.8877
261 1A7 0.8877
262 AOT 0.8875
263 BWD 0.8872
264 64Z 0.8871
265 TIH 0.8871
266 YIH 0.8870
267 TAG 0.8866
268 4Z1 0.8862
269 0XR 0.8861
270 EYV 0.8860
271 GLU 0.8857
272 IS2 0.8856
273 AHN 0.8856
274 GZ2 0.8855
275 SSC 0.8854
276 6C8 0.8854
277 HNT 0.8853
278 HMS 0.8848
279 CWD 0.8845
280 TRP 0.8844
281 5O5 0.8844
282 GLR 0.8844
283 SYE 0.8841
284 MTL 0.8841
285 M4T 0.8841
286 JCZ 0.8838
287 N7I 0.8837
288 DEZ 0.8836
289 BP7 0.8835
290 1FD 0.8834
291 MF3 0.8833
292 4TP 0.8833
293 DTR 0.8831
294 6C5 0.8830
295 FMQ 0.8829
296 833 0.8829
297 3VX 0.8825
298 LR8 0.8825
299 TZF 0.8824
300 TSR 0.8823
301 RNO 0.8821
302 492 0.8821
303 3QM 0.8821
304 T03 0.8820
305 0NX 0.8818
306 DI6 0.8818
307 GLO 0.8817
308 BNL 0.8816
309 MD6 0.8814
310 SHI 0.8814
311 CUW 0.8814
312 HNL 0.8813
313 IAC 0.8812
314 6HP 0.8811
315 SNO 0.8811
316 TZP 0.8809
317 UA5 0.8807
318 LYS 0.8804
319 4NS 0.8804
320 6C9 0.8804
321 88L 0.8802
322 KDG 0.8801
323 ONH 0.8799
324 DE5 0.8797
325 EPE 0.8796
326 DER 0.8795
327 3SU 0.8795
328 A51 0.8794
329 R2P 0.8787
330 1X4 0.8786
331 K80 0.8785
332 IOS 0.8784
333 HJH 0.8783
334 PMP 0.8783
335 PEA 0.8781
336 CIY 0.8780
337 F98 0.8778
338 IC9 0.8777
339 SX2 0.8775
340 CXH 0.8774
341 S7A 0.8774
342 C9M 0.8773
343 G14 0.8773
344 NY4 0.8772
345 2JJ 0.8771
346 795 0.8770
347 XRX 0.8770
348 I3E 0.8769
349 QUS 0.8767
350 HSX 0.8766
351 RP5 0.8763
352 C53 0.8762
353 3PG 0.8760
354 4NP 0.8760
355 A6P 0.8759
356 49F 0.8758
357 X1R 0.8756
358 5OY 0.8756
359 5TT 0.8756
360 PEL 0.8756
361 LNR 0.8755
362 3GZ 0.8754
363 EZL 0.8754
364 RLG 0.8753
365 36E 0.8753
366 N4E 0.8747
367 2HG 0.8745
368 DEW 0.8744
369 BL0 0.8743
370 9VZ 0.8742
371 CIR 0.8741
372 NFZ 0.8741
373 5XA 0.8741
374 CEE 0.8740
375 6C4 0.8738
376 M28 0.8735
377 X04 0.8733
378 HLP 0.8733
379 KMY 0.8731
380 14W 0.8728
381 I4B 0.8727
382 K4V 0.8726
383 TU0 0.8723
384 6Q3 0.8723
385 3R4 0.8723
386 AMQ 0.8721
387 Z70 0.8718
388 STT 0.8718
389 GNW 0.8715
390 A5P 0.8714
391 271 0.8711
392 S2G 0.8710
393 ODK 0.8710
394 Q06 0.8709
395 G6P 0.8708
396 B09 0.8708
397 7MW 0.8707
398 54E 0.8705
399 CTE 0.8703
400 DGL 0.8703
401 4HB 0.8702
402 SDD 0.8702
403 5LD 0.8702
404 3LR 0.8700
405 L99 0.8696
406 ZZU 0.8693
407 EGR 0.8690
408 PHU 0.8687
409 5WN 0.8687
410 HNK 0.8684
411 PRO GLY 0.8682
412 DXG 0.8681
413 1EB 0.8681
414 ERZ 0.8678
415 2O8 0.8677
416 GLP 0.8676
417 50C 0.8675
418 S0E 0.8675
419 JGB 0.8674
420 9NB 0.8674
421 BG6 0.8674
422 YIP 0.8673
423 HNM 0.8673
424 4XF 0.8672
425 JPQ 0.8672
426 11X 0.8672
427 API 0.8671
428 EYY 0.8671
429 3VQ 0.8670
430 PF1 0.8670
431 SB7 0.8668
432 BQ2 0.8667
433 A98 0.8665
434 AG2 0.8664
435 PIY 0.8660
436 XDK 0.8657
437 3IL 0.8655
438 7FU 0.8651
439 2BX 0.8648
440 GGL 0.8647
441 2IT 0.8646
442 DDU 0.8641
443 CLU 0.8640
444 AOY 0.8640
445 ZON 0.8640
446 9GB 0.8640
447 1FE 0.8638
448 B15 0.8638
449 4PN 0.8635
450 A6W 0.8634
451 6XA 0.8627
452 PXP 0.8627
453 4R1 0.8624
454 ENV 0.8615
455 RSV 0.8615
456 LTN 0.8613
457 86L 0.8613
458 PIM 0.8611
459 KYN 0.8607
460 7O4 0.8603
461 A7N 0.8600
462 0L1 0.8596
463 7UC 0.8595
464 SG3 0.8592
465 HSO 0.8592
466 58X 0.8590
467 3TC 0.8587
468 F5C 0.8586
469 TL6 0.8583
470 6L6 0.8580
471 SOL 0.8570
472 ONL 0.8564
473 8ZE 0.8563
474 SJK 0.8560
475 7VP 0.8556
476 AWE 0.8553
477 3OL 0.8544
478 KTA 0.8542
479 DUR 0.8527
480 M6P 0.8509
481 OCA 0.8509
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5FNU; Ligand: L6I; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 5fnu.bio1) has 42 residues
No: Leader PDB Ligand Sequence Similarity
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