Receptor
PDB id Resolution Class Description Source Keywords
5GP7 1.5 Å EC: 2.4.2.30 STRUCTURAL BASIS FOR THE BINDING BETWEEN TANKYRASE-1 AND USP HOMO SAPIENS TANKYRASE USP25 ANKYRIN REPEATS TRANSFERASE
Ref.: USP25 REGULATES WNT SIGNALING BY CONTROLLING THE ST OF TANKYRASES GENES DEV. V. 31 1024 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL A:1002;
A:1001;
 Invalid;
Invalid;
 none;
none;
 submit data
92.094 C3 H8 O3 C(C(C...
SER LEU SER ARG THR PRO ALA ASP GLY ARG B:1046;
 Valid;
 Atoms found LESS than expected: % Diff = 0.054;
 submit data
n/a n/a
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5GP7 1.5 Å EC: 2.4.2.30 STRUCTURAL BASIS FOR THE BINDING BETWEEN TANKYRASE-1 AND USP HOMO SAPIENS TANKYRASE USP25 ANKYRIN REPEATS TRANSFERASE
Ref.: USP25 REGULATES WNT SIGNALING BY CONTROLLING THE ST OF TANKYRASES GENES DEV. V. 31 1024 2017
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 18 families.
1 5GP7 - SER LEU SER ARG THR PRO ALA ASP GLY ARG n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 14 families.
1 5GP7 - SER LEU SER ARG THR PRO ALA ASP GLY ARG n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 5GP7 - SER LEU SER ARG THR PRO ALA ASP GLY ARG n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: SER LEU SER ARG THR PRO ALA ASP GLY ARG; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Ligands (3D)
Ligand no: 1; Ligand: SER LEU SER ARG THR PRO ALA ASP GLY ARG; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5GP7; Ligand: SER LEU SER ARG THR PRO ALA ASP GLY ARG; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 5gp7.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
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