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Receptor
PDB id Resolution Class Description Source Keywords
5GZ6 1.74 Å EC: 1.4.1.16 STRUCTURE OF D-AMINO ACID DEHYDROGENASE IN COMPLEX WITH NADP KETO-6-AMINOCAPRONIC ACID UREIBACILLUS THERMOSPHAERICUS ROSSMANN FOLD OXIDOREDUCTASE
Ref.: STRUCTURE-BASED ENGINEERING OF AN ARTIFICIALLY GENE NADP+-DEPENDENT D-AMINO ACID DEHYDROGENASE APPL. ENVIRON. MICROBIOL. V. 83 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SO4 B:3002;
A:1003;
Invalid;
Invalid;
none;
none;
submit data
96.063 O4 S [O-]S...
NDP A:1001;
Valid;
none;
submit data
745.421 C21 H30 N7 O17 P3 c1nc(...
7C3 A:1002;
Valid;
none;
submit data
145.156 C6 H11 N O3 C(CCN...
ACT B:3001;
Invalid;
none;
submit data
59.044 C2 H3 O2 CC(=O...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5GZ6 1.74 Å EC: 1.4.1.16 STRUCTURE OF D-AMINO ACID DEHYDROGENASE IN COMPLEX WITH NADP KETO-6-AMINOCAPRONIC ACID UREIBACILLUS THERMOSPHAERICUS ROSSMANN FOLD OXIDOREDUCTASE
Ref.: STRUCTURE-BASED ENGINEERING OF AN ARTIFICIALLY GENE NADP+-DEPENDENT D-AMINO ACID DEHYDROGENASE APPL. ENVIRON. MICROBIOL. V. 83 2017
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 5GZ3 - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
2 3WYC - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
3 5GZ6 - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 5GZ3 - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
2 3WYC - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
3 5GZ6 - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
50% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5GZ3 - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
2 3WYC - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
3 5GZ6 - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
4 1F06 Ki = 5 uM 2NP C8 H13 N O4 C=C(CCC[C@....
5 1DAP - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
6 3DAP - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
7 2DAP - API C7 H14 N2 O4 C(C[C@H](C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: NDP; Similar ligands found: 172
No: Ligand ECFP6 Tc MDL keys Tc
1 NDP 1 1
2 0WD 0.827273 1
3 NAI 0.803738 0.986842
4 NMN AMP PO4 0.794643 0.948052
5 NPW 0.692308 0.962025
6 NZQ 0.686441 0.987013
7 1DG 0.68 1
8 DG1 0.68 1
9 A2R 0.650943 0.909091
10 A22 0.64486 0.934211
11 TXP 0.644628 0.924051
12 ATR 0.640777 0.894737
13 NA7 0.636364 0.886076
14 XNP 0.620968 0.949367
15 AP0 0.598361 0.948718
16 A2P 0.598039 0.881579
17 NJP 0.574803 0.923077
18 25L 0.550847 0.934211
19 ODP 0.550388 0.936709
20 NAX 0.544 0.949367
21 25A 0.53913 0.921053
22 80F 0.537879 0.914634
23 2AM 0.529412 0.87013
24 6V0 0.519685 0.974026
25 NAP 0.514493 0.922078
26 7L1 0.507143 0.763441
27 EAD 0.507143 0.949367
28 A2D 0.504673 0.921053
29 TXE 0.503876 0.935897
30 NA0 0.496454 0.910256
31 TXD 0.496124 0.911392
32 SAP 0.495575 0.875
33 AGS 0.495575 0.875
34 P1H 0.493056 0.925926
35 CO7 0.489796 0.791209
36 TAP 0.489362 0.864198
37 PAP 0.482456 0.907895
38 BA3 0.481818 0.921053
39 NAJ PZO 0.478261 0.924051
40 ATP 0.477876 0.921053
41 HEJ 0.477876 0.921053
42 B4P 0.477477 0.921053
43 AP5 0.477477 0.921053
44 ADP 0.477477 0.921053
45 OAD 0.47541 0.897436
46 AR6 0.473684 0.896104
47 AQP 0.473684 0.921053
48 5FA 0.473684 0.921053
49 APR 0.473684 0.896104
50 AN2 0.473214 0.909091
51 3OD 0.467742 0.897436
52 50T 0.464912 0.884615
53 NAJ PYZ 0.464789 0.879518
54 9X8 0.463415 0.851852
55 PO4 PO4 A A A A PO4 0.463415 0.857143
56 V3L 0.461538 0.896104
57 2A5 0.46087 0.85
58 AT4 0.460177 0.886076
59 A1R 0.459016 0.841463
60 4AD 0.459016 0.875
61 ADQ 0.459016 0.897436
62 OVE 0.458716 0.8375
63 OMR 0.458647 0.813953
64 PPS 0.457627 0.811765
65 AD9 0.456897 0.897436
66 CA0 0.45614 0.897436
67 M33 0.45614 0.884615
68 ADJ 0.455882 0.879518
69 A3P 0.455357 0.894737
70 ACP 0.452174 0.897436
71 ENP 0.451613 0.85
72 UP5 0.451128 0.948052
73 SRP 0.45 0.8625
74 ANP 0.449153 0.897436
75 ACQ 0.449153 0.897436
76 PRX 0.448276 0.82716
77 A3R 0.447154 0.841463
78 5AL 0.445378 0.884615
79 7D4 0.443478 0.8375
80 ADX 0.443478 0.811765
81 6YZ 0.438017 0.897436
82 A 0.436364 0.894737
83 AMP 0.436364 0.894737
84 4TC 0.433824 0.924051
85 7D3 0.433628 0.8375
86 DCA 0.433566 0.788889
87 ETB 0.433566 0.797753
88 BIS 0.433071 0.864198
89 1ZZ 0.433071 0.802326
90 00A 0.432 0.864198
91 ATF 0.429752 0.886076
92 DQV 0.428571 0.934211
93 0T1 0.427586 0.788889
94 5SV 0.427419 0.788235
95 8QN 0.427419 0.884615
96 3AM 0.427273 0.857143
97 N01 0.426573 0.884615
98 PR8 0.425197 0.811765
99 LAD 0.425197 0.821429
100 WAQ 0.425197 0.841463
101 DTP 0.425 0.8375
102 AMO 0.424 0.886076
103 PAJ 0.424 0.843373
104 APC 0.423729 0.886076
105 UPA 0.423358 0.935897
106 48N 0.422222 0.853659
107 FYA 0.421875 0.860759
108 PTJ 0.421875 0.853659
109 CNA 0.421429 0.910256
110 PUA 0.42069 0.9125
111 DND 0.419118 0.910256
112 NXX 0.419118 0.910256
113 AV2 0.418033 0.848101
114 COA 0.417808 0.788889
115 3UK 0.417323 0.897436
116 OOB 0.416 0.909091
117 IVC 0.415584 0.78022
118 DAT 0.415254 0.8375
119 NDO 0.414966 0.897436
120 139 0.414286 0.901235
121 B5V 0.414062 0.886076
122 T99 0.413223 0.886076
123 TAT 0.413223 0.886076
124 3AT 0.413223 0.896104
125 YLB 0.413043 0.784091
126 62F 0.4125 0.823529
127 ABM 0.412281 0.848101
128 B5M 0.412214 0.875
129 YAP 0.412214 0.875
130 YLP 0.411765 0.784091
131 NB8 0.410853 0.853659
132 ME8 0.410853 0.802326
133 SON 0.410256 0.886076
134 DLL 0.409449 0.909091
135 AHX 0.409449 0.853659
136 CAO 0.409396 0.763441
137 30N 0.409396 0.72449
138 AMX 0.409396 0.797753
139 COS 0.409396 0.771739
140 7D5 0.409091 0.8125
141 4UW 0.408759 0.9125
142 F2R 0.408451 0.825581
143 APX 0.407692 0.841463
144 SRA 0.40708 0.85
145 CMX 0.406667 0.788889
146 SCO 0.406667 0.788889
147 TYM 0.405797 0.886076
148 COD 0.405594 0.777778
149 CA6 0.405229 0.70297
150 OXK 0.405229 0.771739
151 AP2 0.405172 0.886076
152 A12 0.405172 0.886076
153 9SN 0.40458 0.853659
154 LAQ 0.404412 0.802326
155 T5A 0.404255 0.914634
156 FAM 0.403974 0.771739
157 ACO 0.403974 0.763441
158 FCX 0.403974 0.763441
159 VO4 ADP 0.403226 0.860759
160 ADP VO4 0.403226 0.860759
161 YLC 0.402878 0.823529
162 1VU 0.402597 0.763441
163 B5Y 0.401515 0.875
164 FA5 0.401515 0.886076
165 HAX 0.401316 0.771739
166 AR6 AR6 0.4 0.871795
167 CAJ 0.4 0.771739
168 AFH 0.4 0.843373
169 APU 0.4 0.923077
170 A U 0.4 0.898734
171 TXA 0.4 0.886076
172 4UU 0.4 0.948052
Ligand no: 2; Ligand: 7C3; Similar ligands found: 8
No: Ligand ECFP6 Tc MDL keys Tc
1 7C3 1 1
2 OOG 0.466667 0.642857
3 ACA 0.451613 0.821429
4 011 0.4375 0.793103
5 ABU 0.428571 0.814815
6 8AC 0.424242 0.793103
7 26P 0.416667 0.71875
8 JX7 0.405405 0.722222
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5GZ6; Ligand: NDP; Similar sites found with APoc: 809
This union binding pocket(no: 1) in the query (biounit: 5gz6.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 1WUW TSU None
2 5DOZ NDP 1.22699
3 1Q0H NDP 1.22699
4 1Q0H FOM 1.22699
5 3JYN NDP 1.23077
6 1FWV SGA MAG FUC 1.49254
7 2AG8 NAP 1.52091
8 1SAY PYR 1.53374
9 1KEV NDP 1.53374
10 5KMS NAD 1.53374
11 5KMS FAD 1.53374
12 1SOW NAD 1.53374
13 6C4M NAP 1.53374
14 1ORR NAD 1.53374
15 3C1O NAP 1.55763
16 4UP3 NDP 1.59236
17 4UP3 FAD 1.59236
18 1HYE NAP 1.59744
19 3NGL NAP 1.81159
20 2B4Q NAP 1.81159
21 4GKV NAD 1.84049
22 4B63 NAP 1.84049
23 3GFB NAD 1.84049
24 1PL6 NAD 1.84049
25 4B63 FAD 1.84049
26 4B63 ORN 1.84049
27 1VQW FAD 1.84049
28 2GVC FAD 1.84049
29 2GV8 NDP 1.84049
30 1XHC FAD 1.84049
31 2GV8 FAD 1.84049
32 2DFV NAD 1.84049
33 3WGT FAD 1.84049
34 3WGT QSC 1.84049
35 4RSL FAD 1.84049
36 4NTD FAD 1.84049
37 6F97 FAD 1.84049
38 1D4D FAD 1.84049
39 3G5S FAD 1.84049
40 1V6A TRE 1.84049
41 4C3Y FAD 1.84049
42 3DAG FEG 1.84049
43 1N1G BCP 1.84049
44 1VDC FAD 1.84049
45 1PL6 572 1.84049
46 1M2W NAD 1.84049
47 1LJ8 NAD 1.84049
48 4C3Y ANB 1.84049
49 1EZ4 NAD 1.88679
50 4D3F NAP 1.93548
51 1DIG L37 1.96078
52 1DIG NAP 1.96078
53 5YAP NAI 2.10526
54 5YAP 8S0 2.10526
55 5O9F 9ON 2.14724
56 5O9F NAD 2.14724
57 1H2B NAJ 2.14724
58 4XYB NDP 2.14724
59 5A04 NDP 2.14724
60 2YVF NAD 2.14724
61 2YVF FAD 2.14724
62 3ITJ CIT 2.14724
63 5TWB FAD 2.14724
64 4EMI NAD 2.14724
65 2WET FAD 2.14724
66 2RGO FAD 2.14724
67 1GET NAP 2.14724
68 5TUF TDC 2.14724
69 3QJ4 FAD 2.14724
70 5TUF FAD 2.14724
71 3ETG GLU 2.14724
72 1PGP 6PG 2.14724
73 2RGH FAD 2.14724
74 1U1I NAD 2.14724
75 4EMI FAD 2.14724
76 3ETG GTP 2.14724
77 1GET FAD 2.14724
78 1I8T FAD 2.14724
79 3ETG NDP 2.14724
80 1LDM NAD 2.14724
81 3ITJ FAD 2.14724
82 4KOA NDP 2.14724
83 4UP4 GAL NAG 2.14724
84 5A04 BGC 2.14724
85 2JB2 PHE 2.14724
86 2JB2 FAD 2.14724
87 3A06 FOM 2.14724
88 3A06 NDP 2.14724
89 2CUL FAD 2.15517
90 5VKT NAP 2.20994
91 3GGO ENO 2.2293
92 3GGO NAI 2.2293
93 5FI3 NAP 2.2409
94 2Q0L NAP 2.2508
95 2Q0L FAD 2.2508
96 1YJQ NAP 2.31023
97 2PV7 NAD 2.34899
98 5U5G NAP 2.37288
99 3B1F NAD 2.41379
100 1WP4 NDP 2.42215
101 2CVZ NDP 2.42215
102 4RDH AMP 2.43056
103 4RDI ATP 2.43056
104 5Z21 NAI 2.45399
105 3FPZ AHZ 2.45399
106 2GZ3 NAP 2.45399
107 3UOY FAD 2.45399
108 3UOY NAP 2.45399
109 2NAD NAD 2.45399
110 3ZNN FAD 2.45399
111 3ZNN 4WL 2.45399
112 1QO8 FAD 2.45399
113 3AB1 FAD 2.45399
114 4A0S NAP 2.45399
115 4ZGS NAD 2.45399
116 4MO2 FAD 2.45399
117 4MO2 FDA 2.45399
118 4JNA FAD 2.45399
119 1D1T NAD 2.45399
120 5MQ6 NDP 2.45399
121 2V6G NAP 2.45399
122 6C4T NA7 2.45399
123 2Q1S NAI 2.45399
124 1UP7 NAD 2.45399
125 1P0F NAP 2.45399
126 3I6I NDP 2.45399
127 4WAS COO 2.45399
128 4WAS NAP 2.45399
129 1TB4 PEJ 2.45399
130 1N9G NAP 2.45399
131 5YU3 NAD 2.45399
132 5YU3 PRO 2.45399
133 2G5C NAD 2.4911
134 1LDN NAD 2.53165
135 4D79 ATP 2.53623
136 4L50 D8X 2.63158
137 1O6Z NAD 2.64026
138 5FEU NAP 2.74914
139 2CDC XYS 2.76074
140 2CDC XYP 2.76074
141 1YKJ FAD 2.76074
142 1YKJ PHB 2.76074
143 4AP3 FAD 2.76074
144 4AP3 NAP 2.76074
145 4J36 1HR 2.76074
146 4J36 FAD 2.76074
147 2B5W NAP 2.76074
148 2GSD NAD 2.76074
149 4USR FAD 2.76074
150 5Z75 NAD 2.76074
151 3GDN FAD 2.76074
152 3GDN HBX 2.76074
153 2B9W FAD 2.76074
154 4RVU NDP 2.76074
155 2CDC NAP 2.76074
156 2GLX NDP 2.76074
157 1PJS NAD 2.76074
158 2DM6 NAP 2.76074
159 1QMG APX 2.76074
160 2DM6 IMN 2.76074
161 1ZQ9 SAM 2.80702
162 3OA2 NAD 2.83019
163 3HAD NAD 2.92208
164 5JE8 NAD 2.98013
165 2DBZ NAP 2.99401
166 3RFV NAI 2.99625
167 3RFV 15L 2.99625
168 3OZ2 FAD 3.02267
169 5Y8L NAD 3.05085
170 5Y8L HUI 3.05085
171 1DLJ NAI 3.06748
172 2VHW NAI 3.06748
173 1HKU NAD 3.06748
174 1DLJ UGA 3.06748
175 2O4C NAD 3.06748
176 3LZW FAD 3.06748
177 3LZW NAP 3.06748
178 4W6Z 8ID 3.06748
179 4CNK FAD 3.06748
180 3SQP FAD 3.06748
181 3KLJ FAD 3.06748
182 4BV6 FAD 3.06748
183 3BAZ NAP 3.06748
184 3GD4 NAD 3.06748
185 3GD4 FAD 3.06748
186 5X68 FAD 3.06748
187 2ZXI FAD 3.06748
188 1GPE FAD 3.06748
189 2R4J 13P 3.06748
190 2R4J FAD 3.06748
191 1BZL GCG 3.06748
192 1BZL FAD 3.06748
193 1VKO NAD 3.06748
194 6F7L FAD 3.06748
195 5K0A FAD 3.06748
196 5MB4 NAG 3.06748
197 6EL3 NAP 3.06748
198 4G5H UD7 3.06748
199 4G5H NAP 3.06748
200 4TXI FAD 3.06748
201 1VL0 NAI 3.08219
202 5FFF NAP 3.11284
203 2ZB3 NDP 3.11615
204 4TSK NDP 3.14286
205 1J5P NAD 3.16206
206 3IHG FAD 3.17757
207 4EA7 COA 3.18182
208 4EA7 JB2 3.18182
209 3VPH OXM 3.22581
210 3VPH NAD 3.22581
211 1GUZ NAD 3.22581
212 1GV0 NAD 3.22581
213 5NE2 DGL 3.23741
214 1KYQ NAD 3.28467
215 4RF2 NAP 3.30882
216 2DT5 NAD 3.31754
217 1YQD NAP 3.37423
218 5H81 NAP 3.37423
219 3S5W NAP 3.37423
220 4L8V NAP 3.37423
221 4BVA T3 3.37423
222 1LVL NAD 3.37423
223 5AOV NAP 3.37423
224 6GAS FAD 3.37423
225 4X9M FAD 3.37423
226 1B8U OAA 3.37423
227 5BRT CH9 3.37423
228 5BRT FAD 3.37423
229 1B8U NAD 3.37423
230 5J7X FAD 3.37423
231 4BVA NDP 3.37423
232 5MBX FAD 3.37423
233 5MBX SP5 3.37423
234 1SC6 NAD 3.37423
235 1LVL FAD 3.37423
236 6H3O FAD 3.37423
237 6BII NAP 3.37423
238 1Z82 NDP 3.37423
239 4YT4 FE9 3.37423
240 5HSA FAS 3.37423
241 1KJ8 GAR 3.37423
242 5NUF NAD 3.37423
243 5NUE NAD 3.37423
244 6FP4 FAD 3.37423
245 6FP4 E1T 3.37423
246 3S5W FAD 3.37423
247 1RM4 NDP 3.37423
248 4B7X NAP 3.37423
249 1OMO NAD 3.41615
250 3H8V ATP 3.42466
251 1VL1 CIT 3.44828
252 1NVT NAP 3.48432
253 1HYH NAD 3.55987
254 2F1K NAP 3.58423
255 6A0S NDP 3.61446
256 6A0S HSE 3.61446
257 6AA8 NAD 3.64238
258 3NJ4 NAD 3.68098
259 3NJ4 AFX 3.68098
260 5NMX NAP 3.68098
261 1E3I CXF 3.68098
262 4MOP 2H5 3.68098
263 2QA1 FAD 3.68098
264 3CGD FAD 3.68098
265 4OPC PGT 3.68098
266 5GSN FAD 3.68098
267 5GSN NAP 3.68098
268 4OPC FDA 3.68098
269 3CGD COA 3.68098
270 3CGD NAD 3.68098
271 3NYC FAD 3.68098
272 3NYC IAR 3.68098
273 3AYI HCI 3.68098
274 3AYI FAD 3.68098
275 5GSN MMZ 3.68098
276 5W3K NDP 3.68098
277 5W3K 9TY 3.68098
278 3T31 DCQ 3.68098
279 3T31 FAD 3.68098
280 5NMX FAD 3.68098
281 3CGB FAD 3.68098
282 4M52 FAD 3.68098
283 5JWC FAD 3.68098
284 4REP FAD 3.68098
285 4M52 M52 3.68098
286 2A8X FAD 3.68098
287 5DF1 NAP 3.68098
288 5DF1 58X 3.68098
289 3FG2 FAD 3.68098
290 2ZB4 5OP 3.68098
291 2ZB4 NAP 3.68098
292 4HXY NDP 3.68098
293 5TUK FAD 3.68098
294 4JGP PYR 3.68664
295 1HDR NAD 3.68852
296 1A5Z NAD 3.76176
297 3O9Z NAD 3.84615
298 3O9Z AKG 3.84615
299 5X20 NAD 3.84615
300 6CI9 NAP 3.861
301 1UXG FUM 3.8835
302 1UXG NAD 3.8835
303 4YSX FAD 3.90071
304 5U8U FAD 3.98773
305 1KOL NAD 3.98773
306 1RYD NDP 3.98773
307 1H6C NDP 3.98773
308 1H6C SIN 3.98773
309 4XB2 NDP 3.98773
310 4YKG NAD 3.98773
311 4D04 FAD 3.98773
312 4D04 NAP 3.98773
313 4K5S FAD 3.98773
314 4K5S PM0 3.98773
315 2GCG NDP 3.98773
316 1EBF NAD 3.98773
317 1KNR FAD 3.98773
318 3LXD FAD 3.98773
319 4YKG FAD 3.98773
320 1RSG FAD 3.98773
321 4FWE FAD 3.98773
322 2Z3Y F2N 3.98773
323 1YY5 FAD 3.98773
324 3K7M FAD 3.98773
325 5HXI FAD 3.98773
326 4XB2 HSE 3.98773
327 3ULK NDP 3.98773
328 5HXI 5HN 3.98773
329 5H06 MAL 3.98773
330 4TQK NAG 3.98773
331 3QWB NDP 3.98773
332 5N6C NAD 4
333 5O4J PJL 4.0146
334 5O4J SAH 4.0146
335 5O4J 9KH 4.0146
336 3F8D FAD 4.02477
337 5OJL TXP 4.02685
338 4CJX NAP 4.07523
339 4J7U YTZ 4.16667
340 4J7U NAP 4.16667
341 2EV9 SKM 4.18251
342 2EV9 NAP 4.18251
343 5WQP NCA 4.2735
344 5WQP NAP 4.2735
345 6F3N NAD 4.29448
346 6F3N ADN 4.29448
347 5M67 ADE 4.29448
348 5M67 NAD 4.29448
349 4ZVV GN0 4.29448
350 4ZVV NAD 4.29448
351 2ZJ1 ARJ 4.29448
352 2ZJ1 NAD 4.29448
353 1CDO NAD 4.29448
354 2FZW NAD 4.29448
355 5M67 3D1 4.29448
356 4ZCC NAI 4.29448
357 4ZCC FAD 4.29448
358 1COY FAD 4.29448
359 1MO9 KPC 4.29448
360 1ZK7 FAD 4.29448
361 1MO9 FAD 4.29448
362 2Y6Q I7T 4.29448
363 2Y6Q FAD 4.29448
364 5ZBC FAD 4.29448
365 1COY AND 4.29448
366 4MDH NAD 4.29448
367 4RPL FAD 4.29448
368 4RPL 3UC 4.29448
369 1FEC FAD 4.29448
370 4JJF N2I 4.29448
371 4JJF FE9 4.29448
372 4IV9 FAD 4.29448
373 5MDH NAD 4.29448
374 6F3M NAD 4.29448
375 1LLU NAD 4.29448
376 3Q3C NAD 4.34783
377 3CTY FAD 4.38871
378 1P77 ATR 4.41176
379 4XQC 13D 4.60123
380 2RAB NAD 4.60123
381 1X7D ORN 4.60123
382 1X7D NAD 4.60123
383 2C7G FAD 4.60123
384 2C7G ODP 4.60123
385 5EZ7 FAD 4.60123
386 5EB4 FAD 4.60123
387 3K5I AIR 4.60123
388 5NA1 FAD 4.60123
389 1RM0 D6P 4.60123
390 1Q9I FAD 4.60123
391 1Q9I TEO 4.60123
392 1RM0 NAI 4.60123
393 2RAB FAD 4.60123
394 4RQU NAD 4.60123
395 2I3G NAP 4.60123
396 1O0S NAI 4.60123
397 4OOE FOM 4.60123
398 4OOE NDP 4.60123
399 1R37 NAD 4.60123
400 3Q9T FAY 4.60123
401 2C29 DQH 4.60123
402 2C29 NAP 4.60123
403 1GR0 NAD 4.60123
404 3H5N ATP 4.60123
405 4XQC NAD 4.60123
406 5U5N NAD 4.6595
407 1LTH NAD 4.70219
408 2DUR MAN MAN 4.74308
409 1NVM NAD 4.80769
410 1LUA NAP 4.87805
411 1RYI GOA 4.90798
412 6GAR FAD 4.90798
413 1RYI FAD 4.90798
414 5Y77 FAD 4.90798
415 4YRY NAD 4.90798
416 4YRY FAD 4.90798
417 1YQZ FAD 4.90798
418 4E5N NAD 4.90798
419 1BW9 NAD 4.90798
420 1BXG NAD 4.90798
421 1C1X NAD 4.90798
422 1X87 NAD 4.90798
423 1ELI PYC 4.90798
424 1Y8Q ATP 4.90798
425 2AG5 NAD 4.90798
426 5DN9 NAD 4.90798
427 5Y1G AKB 4.90798
428 5Y1G NAD 4.90798
429 4MP8 NAD 4.90798
430 4MP8 MLI 4.90798
431 4TQG NDP 4.95356
432 5DP2 NAP 4.97076
433 2RNF UM3 5
434 3RGG AIR 5.03145
435 3A4V NAD 5.04732
436 3A4V PYR 5.04732
437 1WMA NDP 5.07246
438 1WMA AB3 5.07246
439 6GNA FAD 5.20833
440 2NVK NAP 5.21472
441 1C0I FAD 5.21472
442 1C0I BE2 5.21472
443 1GTE FAD 5.21472
444 6FHO FAD 5.21472
445 5OC1 FAD 5.21472
446 4Z24 FAD 5.21472
447 4MIG G3F 5.21472
448 2AQJ FAD 5.21472
449 2AQJ TRP 5.21472
450 1YKF NAP 5.21472
451 1F8G NAD 5.21472
452 2NVK FAD 5.21472
453 4AT0 FAD 5.21472
454 6CEP NAD 5.21472
455 4Y1B NAP 5.21472
456 5A1T NAI 5.21472
457 6CEP OXM 5.21472
458 2OOR NAD 5.21472
459 5MLR NAP 5.21472
460 5MLR GRQ 5.21472
461 5A1T OXM 5.21472
462 1GQ2 NAP 5.21472
463 1NM5 NAP 5.21472
464 1NM5 NAD 5.21472
465 2O07 SPD 5.26316
466 2O07 MTA 5.26316
467 5JCA FAD 5.28169
468 5JCA NDP 5.28169
469 1TDF NAP 5.37975
470 1TDF FAD 5.37975
471 2P0D I3P 5.42636
472 1FL2 FAD 5.48387
473 5OCM NAP 5.49828
474 5NII FAD 5.50162
475 1J49 NAD 5.52147
476 5J5Z FAD 5.52147
477 5G3U FDA 5.52147
478 5G3U ITW 5.52147
479 3RNM FAD 5.52147
480 1PS9 FAD 5.52147
481 2XVE FAD 5.52147
482 3CIF G3H 5.52147
483 2XVF FAD 5.52147
484 2GMH FAD 5.52147
485 4JBI NDP 5.52147
486 4BJZ P3A 5.52147
487 4BJZ FAD 5.52147
488 4U8P FDA 5.52147
489 4U8P UDP 5.52147
490 1YB5 NAP 5.52147
491 9LDT NAD 5.52147
492 3CIF NAD 5.52147
493 1PS9 NAP 5.52147
494 9LDB NAD 5.52147
495 5XWV NDP 5.52147
496 5XWV 8H6 5.52147
497 3NKS FAD 5.52147
498 3C7A NAD 5.52147
499 2PK3 A2R 5.60748
500 1RP0 AHZ 5.6338
501 4JK3 NAD 5.79151
502 2HK9 ATR 5.81818
503 2HK9 NAP 5.81818
504 1CF2 NAP 5.82822
505 4HA6 FAD 5.82822
506 1E6E FAD 5.82822
507 1H82 GZZ 5.82822
508 1E1M NAP 5.82822
509 1E1M FAD 5.82822
510 1V59 FAD 5.82822
511 1H82 FAD 5.82822
512 3KB6 NAD 5.82822
513 5ODQ FAD 5.82822
514 2IVD FAD 5.82822
515 2VVM FAD 5.82822
516 2VTD LKM 5.82822
517 1V59 NAD 5.82822
518 5YB7 ORN 5.82822
519 5YB7 FAD 5.82822
520 5FPE 3TR 5.82822
521 3ORF NAD 5.82822
522 2Q7V FAD 5.84615
523 1JNR FAD 6
524 2BRY FAD 6.03622
525 2B4R NAD 6.08696
526 2B4R AES 6.08696
527 2CVQ NDP 6.11621
528 1C3M MAN MAN 6.12245
529 5BVA FAD 6.13497
530 1J0X NAD 6.13497
531 1DSS NAD 6.13497
532 3H9E NAD 6.13497
533 4XDY NAI 6.13497
534 2IXB A2G 6.13497
535 1Q1R FAD 6.13497
536 1ZH8 NAP 6.13497
537 5YEC ATP 6.13497
538 3E1T FAD 6.13497
539 5EOW FAD 6.13497
540 5Z20 NAI 6.13497
541 2VVL FAD 6.13497
542 4EIP FAD 6.13497
543 5UAO FAD 6.13497
544 4EIP K2C 6.13497
545 1OC2 TDX 6.13497
546 2IXB NAD 6.13497
547 1VM6 NAD 6.14035
548 5UAV TFB 6.21118
549 5UAV NDP 6.21118
550 2HMT NAI 6.25
551 5TC4 NAD 6.32911
552 5CAE SIN 6.38978
553 5CAE COA 6.38978
554 3OJO NAD 6.44172
555 5UR0 NAD 6.44172
556 1WDK NAD 6.44172
557 5KOX RFP 6.44172
558 5KOX FAD 6.44172
559 3RC1 NAP 6.44172
560 3LAD FAD 6.44172
561 1UWK NAD 6.44172
562 1UWK URO 6.44172
563 3RC1 TLO 6.44172
564 5JY6 NAD 6.44172
565 4DPL NAP 6.44172
566 3GF4 UPG 6.44172
567 3GF4 FAD 6.44172
568 4J4H NAI 6.56371
569 4J4H 1J1 6.56371
570 1GZ4 ATP 6.74847
571 5TS5 FAD 6.74847
572 5VN0 NAI 6.74847
573 1REO FAD 6.74847
574 5MZI FAD 6.74847
575 5MZI FYK 6.74847
576 4Z0H NAD 6.74847
577 3L4S NAD 6.74847
578 3L4S 3PG 6.74847
579 5VN0 FAD 6.74847
580 3FWN ATR 6.74847
581 2VYN NAD 6.74847
582 5LD5 NAD 6.74847
583 2YYY NAP 6.74847
584 1GAD NAD 6.74847
585 4IDC NDP 6.74847
586 4IDC 1XX 6.74847
587 4YCA NDP 6.80272
588 2RI1 GLP 6.80851
589 1ZEM NAD 6.87023
590 2BKA NDP 7.02479
591 4PLG NAI 7.05521
592 4PLG OXM 7.05521
593 6C4N NAP 7.05521
594 2IID PHE 7.05521
595 2IID FAD 7.05521
596 1MUU NAD 7.05521
597 1MV8 NAD 7.05521
598 1K3T BRZ 7.05521
599 3WMX NAD 7.05521
600 3V1Y NAD 7.05521
601 2FR1 NDP 7.05521
602 1CER NAD 7.05521
603 5BJX NAD 7.05521
604 5BJX UDP 7.05521
605 4I7E PEP 7.21003
606 2GN4 UD1 7.26744
607 2GN4 NDP 7.26744
608 1DRV A3D 7.32601
609 4J1Q NDP 7.32759
610 3WV8 ATP 7.33945
611 2QRK AMP 7.36196
612 3UCL FAD 7.36196
613 3UCL CYH 7.36196
614 3UCL NAP 7.36196
615 6ER9 FAD 7.36196
616 6ER9 NAP 7.36196
617 1PZG A3D 7.36196
618 2HJR APR 7.36196
619 3X0V FAD 7.36196
620 5TTJ FAD 7.36196
621 2D2I NAP 7.36196
622 4KP7 1UQ 7.36196
623 4KP7 NAP 7.36196
624 3WQQ IB3 7.36196
625 3WQQ NDP 7.36196
626 1WDI CIT 7.36196
627 5ZI2 NAD 7.36196
628 3B20 NAD 7.36196
629 5ZI2 ADP 7.36196
630 1T26 GBD 7.45342
631 1T26 NAI 7.45342
632 5L95 AMP 7.5
633 5Z2F NAP 7.54717
634 5X9D 80F 7.56579
635 4B4U NAP 7.59076
636 4QED NAP 7.66129
637 4TM3 FAD 7.66871
638 1DJN ADP 7.66871
639 5JCM NAD 7.66871
640 5ZYN FAD 7.66871
641 5JCM ISD 7.66871
642 5JCM FAD 7.66871
643 3ICS ADP 7.66871
644 3ICT ADP 7.66871
645 2RGJ FAD 7.66871
646 1F8F NAD 7.66871
647 3ICT FAD 7.66871
648 3ICR FAD 7.66871
649 3ICS FAD 7.66871
650 4E13 NAD 7.77385
651 5MIT FAD 7.97546
652 5MIT NAP 7.97546
653 2CDU ADP 7.97546
654 2YG3 FAD 7.97546
655 2CDU FAD 7.97546
656 5GUD NDP 7.97546
657 3L9W AMP 7.97546
658 3L9W GSH 7.97546
659 5GUD 2IT 7.97546
660 5GUD CIT 7.97546
661 4PIV NDP 7.97546
662 1X14 NAD 7.98005
663 5KKA 6V0 8.01282
664 5T2Y 753 8.08081
665 5N0J FAD 8.26211
666 3AXB PRO 8.28221
667 3AXB FAD 8.28221
668 1PN0 IPH 8.28221
669 1PN0 FAD 8.28221
670 3CMC NAD 8.28221
671 1HDG NAD 8.28221
672 2IZ1 ATR 8.28221
673 4DSG FAD 8.28221
674 4DSG UDP 8.28221
675 4EMJ FAD 8.41121
676 5I39 FAD 8.58896
677 2DKH FAD 8.58896
678 2DKH 3HB 8.58896
679 5BUK FAD 8.58896
680 4NTC FAD 8.58896
681 2WPF WPF 8.58896
682 2WPF FAD 8.58896
683 5BSH PRO 8.66426
684 4KQW NAP 8.89571
685 4GUT FAD 8.89571
686 4GUS FAD 8.89571
687 4HSU FAD 8.89571
688 1E5Q NDP 8.89571
689 5WGR FAD 8.89571
690 5AYV KPL 9.06149
691 5AYV NAP 9.06149
692 2Q46 NAP 9.09091
693 2YVJ NAI 9.17431
694 2YVJ FAD 9.17431
695 3WLE NAD 9.20245
696 4PLT NAI 9.20245
697 4PLT OXM 9.20245
698 5XWC 2IT 9.20245
699 5XWC 8GL 9.20245
700 5XWC NAP 9.20245
701 1VI2 NAD 9.33333
702 1O94 ADP 9.375
703 2F5Z FAD 9.375
704 1O97 FAD 9.375
705 2NPX NAD 9.5092
706 3ABI NAD 9.5092
707 2NPX FAD 9.5092
708 3NTA FAD 9.5092
709 3NT6 FAD 9.5092
710 3NTD FAD 9.5092
711 5ZZ6 ADP 9.61539
712 5ZZ6 NAD 9.61539
713 2YY7 NAD 9.61539
714 1NPD NAD 9.72222
715 2QZZ NAP 9.74843
716 2QZZ EMF 9.74843
717 5XVH NAP 9.80392
718 1V8B NAD 9.81595
719 4D7E FAD 9.81595
720 1I36 NAP 9.84848
721 2GAG NAD 10
722 2GAG FAD 10
723 2GAG FOA 10
724 3HDY FDA 10.1227
725 3HDY GDU 10.1227
726 3HDY FAD 10.1227
727 1H9A NAP 10.1227
728 2BOS GLA GAL GLC NBU 10.2941
729 2BOS GLA GAL GLC 10.2941
730 3OND ADN 10.4294
731 3OND NAD 10.4294
732 4YNU FAD 10.4294
733 4YNU LGC 10.4294
734 5TOW ADN 10.7362
735 5TOW NAI 10.7362
736 4USQ FAD 10.7362
737 3QFA FAD 10.7362
738 3TWO NDP 10.7362
739 3FXU TSU 10.8197
740 5G4L NDP 10.8392
741 5K4W NAI 10.9034
742 5K4W THR 10.9034
743 6A3J SOE 11.0429
744 6A3J NAI 11.0429
745 4EDF UPG 11.0429
746 4II2 ATP 11.0429
747 5D4V SAH 11.194
748 4XYM COA 11.3043
749 4XZ3 COA 11.3043
750 1JAY NAP 11.3208
751 3GMB FAD 11.3497
752 1C3V NDP 11.4286
753 2HYQ MAN MAN 11.4754
754 2NU5 NAG 11.4754
755 2GUD MAN 11.4754
756 2NUO BGC 11.4754
757 2GUC MAN 11.4754
758 2HYR BGC GLC 11.4754
759 6GNC FAD 11.5646
760 2E5V FAD 11.9632
761 5E4R NAP 11.9632
762 4XDZ NDP 11.9632
763 2AHR NAP 11.9691
764 1NAA ABL 12.2699
765 1NAA 6FA 12.2699
766 5EES NAP 12.5506
767 2NU8 COA 12.5767
768 2A92 NAI 12.5767
769 4R5M NAP 12.5767
770 4R5M 4NO 12.5767
771 1LC3 NAD 12.585
772 5T9F TYR 12.9151
773 5T9F NAP 12.9151
774 1NYT NAP 12.9151
775 5T9E NAP 12.9151
776 2VT3 ATP 13.0233
777 5OOH 9ZZ 13.1068
778 5OOH NAP 13.1068
779 6AIN FAD 13.1902
780 2HQM FAD 13.1902
781 5J60 FAD 13.4375
782 4OM8 NAD 13.5922
783 5KVS 6XR 13.8037
784 5KVS NAP 13.8037
785 4CQM NAP 13.9344
786 4LHD GLY 14.1104
787 1U3U NAD 14.7239
788 1U3U BNF 14.7239
789 2JHF NAD 14.7239
790 3QWI CUE 15.1852
791 3QV1 NAD 15.8537
792 3QVP FAD 15.9509
793 1LSS NAD 16.4286
794 4JDR FAD 17.1779
795 5FJN BE2 17.3246
796 5FJN FAD 17.3246
797 4J56 FAD 17.5439
798 1YS4 NAP 18.4049
799 3AD8 NAD 20.202
800 3AD8 PYC 20.202
801 3AD8 FAD 20.202
802 5N2I NAP 21.5517
803 2DC1 NAD 27.1186
804 5EIN NAP 27.7778
805 3B1J NAD 28
806 5YRF GLC GLC 30.9859
807 5YRI GLC GLC 30.9859
808 5YRM BGC GLC 30.9859
809 5YRG BGC GLC 30.9859
Pocket No.: 2; Query (leader) PDB : 5GZ6; Ligand: 7C3; Similar sites found with APoc: 760
This union binding pocket(no: 2) in the query (biounit: 5gz6.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 1WUW TSU None
2 5DOZ NDP 1.22699
3 1Q0H NDP 1.22699
4 1Q0H FOM 1.22699
5 3JYN NDP 1.23077
6 1FWV SGA MAG FUC 1.49254
7 2AG8 NAP 1.52091
8 1SAY PYR 1.53374
9 1KEV NDP 1.53374
10 5KMS NAD 1.53374
11 5KMS FAD 1.53374
12 1SOW NAD 1.53374
13 6C4M NAP 1.53374
14 4UP3 NDP 1.59236
15 4UP3 FAD 1.59236
16 1HYE NAP 1.59744
17 3NGL NAP 1.81159
18 3GFB NAD 1.84049
19 4B63 NAP 1.84049
20 1PL6 NAD 1.84049
21 4GKV NAD 1.84049
22 4B63 FAD 1.84049
23 4B63 ORN 1.84049
24 2DFV NAD 1.84049
25 1XHC FAD 1.84049
26 2GV8 NDP 1.84049
27 1VQW FAD 1.84049
28 2GVC FAD 1.84049
29 2GV8 FAD 1.84049
30 3WGT QSC 1.84049
31 3WGT FAD 1.84049
32 1PL6 572 1.84049
33 4RSL FAD 1.84049
34 1V6A TRE 1.84049
35 6F97 FAD 1.84049
36 1D4D FAD 1.84049
37 4NTD FAD 1.84049
38 3G5S FAD 1.84049
39 4C3Y FAD 1.84049
40 1N1G BCP 1.84049
41 3DAG FEG 1.84049
42 4C3Y ANB 1.84049
43 1VDC FAD 1.84049
44 1EZ4 NAD 1.88679
45 4D3F NAP 1.93548
46 1DIG NAP 1.96078
47 1DIG L37 1.96078
48 5YAP 8S0 2.10526
49 5YAP NAI 2.10526
50 5O9F NAD 2.14724
51 5O9F 9ON 2.14724
52 1H2B NAJ 2.14724
53 3ITJ CIT 2.14724
54 4XYB NDP 2.14724
55 5A04 NDP 2.14724
56 2YVF FAD 2.14724
57 2YVF NAD 2.14724
58 4EMI NAD 2.14724
59 1GET NAP 2.14724
60 5TWB FAD 2.14724
61 2WET FAD 2.14724
62 2RGO FAD 2.14724
63 5TUF TDC 2.14724
64 3ETG GLU 2.14724
65 5TUF FAD 2.14724
66 3QJ4 FAD 2.14724
67 3ETG NDP 2.14724
68 1LDM NAD 2.14724
69 4EMI FAD 2.14724
70 4UP4 GAL NAG 2.14724
71 1PGP 6PG 2.14724
72 1U1I NAD 2.14724
73 3ETG GTP 2.14724
74 1GET FAD 2.14724
75 2RGH FAD 2.14724
76 1I8T FAD 2.14724
77 5A04 BGC 2.14724
78 4KOA NDP 2.14724
79 3ITJ FAD 2.14724
80 2CUL FAD 2.15517
81 5VKT NAP 2.20994
82 3GGO ENO 2.2293
83 3GGO NAI 2.2293
84 5FI3 NAP 2.2409
85 2Q0L NAP 2.2508
86 2Q0L FAD 2.2508
87 1YJQ NAP 2.31023
88 2PV7 NAD 2.34899
89 5U5G NAP 2.37288
90 3B1F NAD 2.41379
91 1WP4 NDP 2.42215
92 2CVZ NDP 2.42215
93 4RDH AMP 2.43056
94 4RDI ATP 2.43056
95 2GZ3 NAP 2.45399
96 5Z21 NAI 2.45399
97 3FPZ AHZ 2.45399
98 3ZNN FAD 2.45399
99 3ZNN 4WL 2.45399
100 3UOY NAP 2.45399
101 3UOY FAD 2.45399
102 2NAD NAD 2.45399
103 1QO8 FAD 2.45399
104 4ZGS NAD 2.45399
105 3AB1 FAD 2.45399
106 4A0S NAP 2.45399
107 1D1T NAD 2.45399
108 4MO2 FAD 2.45399
109 4MO2 FDA 2.45399
110 4JNA FAD 2.45399
111 2V6G NAP 2.45399
112 3I6I NDP 2.45399
113 1P0F NAP 2.45399
114 1TB4 PEJ 2.45399
115 2Q1S NAI 2.45399
116 5MQ6 NDP 2.45399
117 5YU3 PRO 2.45399
118 5YU3 NAD 2.45399
119 1N9G NAP 2.45399
120 6C4T NA7 2.45399
121 1UP7 NAD 2.45399
122 2G5C NAD 2.4911
123 1LDN NAD 2.53165
124 4D79 ATP 2.53623
125 4L50 D8X 2.63158
126 1O6Z NAD 2.64026
127 2CDC XYS 2.76074
128 2CDC XYP 2.76074
129 2B5W NAP 2.76074
130 1YKJ PHB 2.76074
131 1YKJ FAD 2.76074
132 4J36 1HR 2.76074
133 4AP3 NAP 2.76074
134 4AP3 FAD 2.76074
135 2GSD NAD 2.76074
136 4J36 FAD 2.76074
137 2CDC NAP 2.76074
138 4USR FAD 2.76074
139 1PJS NAD 2.76074
140 5Z75 NAD 2.76074
141 3GDN HBX 2.76074
142 3GDN FAD 2.76074
143 2B9W FAD 2.76074
144 4RVU NDP 2.76074
145 2GLX NDP 2.76074
146 1QMG APX 2.76074
147 1ZQ9 SAM 2.80702
148 3OA2 NAD 2.83019
149 3HAD NAD 2.92208
150 5JE8 NAD 2.98013
151 2DBZ NAP 2.99401
152 3RFV 15L 2.99625
153 3OZ2 FAD 3.02267
154 5Y8L HUI 3.05085
155 5Y8L NAD 3.05085
156 1DLJ NAI 3.06748
157 1DLJ UGA 3.06748
158 2VHW NAI 3.06748
159 1HKU NAD 3.06748
160 2O4C NAD 3.06748
161 3LZW FAD 3.06748
162 3LZW NAP 3.06748
163 4W6Z 8ID 3.06748
164 3BAZ NAP 3.06748
165 3SQP FAD 3.06748
166 3GD4 NAD 3.06748
167 4CNK FAD 3.06748
168 3KLJ FAD 3.06748
169 4BV6 FAD 3.06748
170 3GD4 FAD 3.06748
171 5X68 FAD 3.06748
172 2ZXI FAD 3.06748
173 2R4J FAD 3.06748
174 2R4J 13P 3.06748
175 1GPE FAD 3.06748
176 1BZL GCG 3.06748
177 1BZL FAD 3.06748
178 1VKO NAD 3.06748
179 5MB4 NAG 3.06748
180 6F7L FAD 3.06748
181 6EL3 NAP 3.06748
182 5K0A FAD 3.06748
183 4G5H NAP 3.06748
184 4G5H UD7 3.06748
185 4TXI FAD 3.06748
186 5FFF NAP