Receptor
PDB id Resolution Class Description Source Keywords
5H5O 2.12 Å EC: 7.-.-.- A CYCLIC-GMP-DEPENDENT SIGNALLING PATHWAY REGULATES BACTERIA PHYTOPATHOGENESIS XANTHOMONAS CAMPESTRIS PV. CAMPESTRIS B100) CYCLIC GMP XC0250 XC0249 SIGNALLING PATHWAY BIOSYNTHETIC
Ref.: A CYCLIC GMP-DEPENDENT SIGNALLING PATHWAY REGULATES BACTERIAL PHYTOPATHOGENESIS EMBO J. V. 32 2430 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PCG B:201;
A:201;
Valid;
Valid;
none;
none;
Kd = 0.293 uM
345.205 C10 H12 N5 O7 P c1nc2...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5H5O 2.12 Å EC: 7.-.-.- A CYCLIC-GMP-DEPENDENT SIGNALLING PATHWAY REGULATES BACTERIA PHYTOPATHOGENESIS XANTHOMONAS CAMPESTRIS PV. CAMPESTRIS B100) CYCLIC GMP XC0250 XC0249 SIGNALLING PATHWAY BIOSYNTHETIC
Ref.: A CYCLIC GMP-DEPENDENT SIGNALLING PATHWAY REGULATES BACTERIAL PHYTOPATHOGENESIS EMBO J. V. 32 2430 2013
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 293 families.
1 5H5O Kd = 0.293 uM PCG C10 H12 N5 O7 P c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 250 families.
1 5H5O Kd = 0.293 uM PCG C10 H12 N5 O7 P c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 204 families.
1 5H5O Kd = 0.293 uM PCG C10 H12 N5 O7 P c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: PCG; Similar ligands found: 57
No: Ligand ECFP6 Tc MDL keys Tc
1 35G 1 1
2 C2E 1 0.986111
3 PCG 1 1
4 4BW 0.806818 0.986111
5 1YD 0.806818 0.986111
6 5GP 5GP 0.743902 0.945205
7 4UR 0.731959 0.986111
8 6SW 0.627907 0.957747
9 1YC 0.616162 0.958333
10 6J7 0.58427 0.946667
11 CMP 0.534091 0.888889
12 2BA 0.534091 0.902778
13 GMP 0.53012 0.84
14 1SY 0.495575 0.986111
15 SGP 0.483871 0.835443
16 6SZ 0.483871 0.902778
17 3GP 0.478261 0.932432
18 1OR 0.474747 0.729412
19 G 0.468085 0.945946
20 5GP 0.468085 0.945946
21 7CH 0.467391 0.875
22 6SX 0.462366 0.847222
23 6JR 0.457944 0.930556
24 G2R 0.457143 0.897436
25 GPX 0.451923 0.906667
26 GP3 0.44898 0.934211
27 2GP 0.446809 0.92
28 GP2 0.444444 0.897436
29 GDP 0.444444 0.933333
30 GNH 0.44 0.921053
31 P2G 0.4375 0.893333
32 G2P 0.436893 0.897436
33 GMV 0.431373 0.909091
34 GTP 0.431373 0.933333
35 ALF 5GP 0.431373 0.851852
36 G1R 0.427184 0.921053
37 GCP 0.427184 0.909091
38 G3D 0.423077 0.945946
39 9GM 0.423077 0.909091
40 GSP 0.423077 0.886076
41 GNP 0.423077 0.909091
42 GDP AF3 0.420561 0.851852
43 G4P 0.415094 0.945946
44 GAV 0.415094 0.897436
45 P1G 0.414141 0.881579
46 Y9Z 0.410714 0.843373
47 GCP G 0.409091 0.906667
48 GDP ALF 0.407407 0.851852
49 ALF GDP 0.407407 0.851852
50 N6R 0.40708 0.818182
51 N6S 0.40708 0.818182
52 G G 0.40708 0.934211
53 G3A 0.403509 0.934211
54 YGP 0.401786 0.8875
55 GPG 0.4 0.922078
56 G5P 0.4 0.934211
57 0O2 0.4 0.945946
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5H5O; Ligand: PCG; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 5h5o.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 5H5O; Ligand: PCG; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 5h5o.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
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