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Receptor
PDB id Resolution Class Description Source Keywords
5HJM 1.76 Å EC: 2.1.1.228 CRYSTAL STRUCTURE OF PYROCOCCUS ABYSSI TRM5A COMPLEXED WITH PYROCOCCUS ABYSSI (STRAIN GE5 / ORSAY)ORGANISM_TAXID: 272844 METHYLTRANSFERASE TRM5A SAM TRNA MODIFICATION TRANSFERAS
Ref.: CRYSTAL STRUCTURES OF THE BIFUNCTIONAL TRNA METHYLTRANSFERASE TRM5A SCI REP V. 6 33553 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MTA A:401;
Valid;
none;
submit data
297.334 C11 H15 N5 O3 S CSC[C...
ACT A:402;
Invalid;
none;
submit data
59.044 C2 H3 O2 CC(=O...
HSL A:403;
Valid;
none;
submit data
101.104 C4 H7 N O2 C1COC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5HJM 1.76 Å EC: 2.1.1.228 CRYSTAL STRUCTURE OF PYROCOCCUS ABYSSI TRM5A COMPLEXED WITH PYROCOCCUS ABYSSI (STRAIN GE5 / ORSAY)ORGANISM_TAXID: 272844 METHYLTRANSFERASE TRM5A SAM TRNA MODIFICATION TRANSFERAS
Ref.: CRYSTAL STRUCTURES OF THE BIFUNCTIONAL TRNA METHYLTRANSFERASE TRM5A SCI REP V. 6 33553 2016
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5HJM - HSL C4 H7 N O2 C1COC(=O)[....
2 5HJI - ADN C10 H13 N5 O4 c1nc(c2c(n....
3 5HJK - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5HJM - HSL C4 H7 N O2 C1COC(=O)[....
2 5HJI - ADN C10 H13 N5 O4 c1nc(c2c(n....
3 5HJK - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5HJM - HSL C4 H7 N O2 C1COC(=O)[....
2 5HJI - ADN C10 H13 N5 O4 c1nc(c2c(n....
3 5HJK - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: MTA; Similar ligands found: 267
No: Ligand ECFP6 Tc MDL keys Tc
1 MTA 1 1
2 DTA 0.786885 0.867647
3 3DH 0.777778 0.938462
4 ADN 0.758621 0.878788
5 RAB 0.758621 0.878788
6 XYA 0.758621 0.878788
7 DSH 0.705882 0.84507
8 5N5 0.704918 0.878788
9 A4D 0.693548 0.907692
10 5CD 0.693548 0.892308
11 EP4 0.6875 0.939394
12 M2T 0.676923 0.940298
13 A7D 0.657534 0.882353
14 5X8 0.64 0.895522
15 5AD 0.639344 0.857143
16 AMP 0.628571 0.794521
17 A 0.628571 0.794521
18 ZAS 0.628571 0.816901
19 LMS 0.628571 0.719512
20 A5D 0.623377 0.867647
21 SAH 0.615385 0.869565
22 ABM 0.60274 0.821918
23 J7C 0.60274 0.794521
24 AAT 0.6 0.797297
25 6RE 0.597222 0.783784
26 SRA 0.597222 0.776316
27 S4M 0.594595 0.84
28 AOC 0.589041 0.880597
29 MAO 0.586667 0.805195
30 S8M 0.583333 0.833333
31 A2D 0.581081 0.773333
32 A3N 0.581081 0.867647
33 5AS 0.578947 0.697674
34 GJV 0.573333 0.773333
35 A12 0.565789 0.74359
36 AP2 0.565789 0.74359
37 BA3 0.565789 0.773333
38 AU1 0.564103 0.753247
39 ADX 0.564103 0.719512
40 M33 0.564103 0.810811
41 MHZ 0.564103 0.805195
42 B4P 0.558442 0.773333
43 AP5 0.558442 0.773333
44 ADP 0.558442 0.773333
45 7D7 0.553846 0.794118
46 Y3J 0.552239 0.80303
47 AN2 0.551282 0.763158
48 AT4 0.551282 0.766234
49 SON 0.551282 0.74359
50 SXZ 0.550562 0.849315
51 PRX 0.55 0.8
52 A6D 0.545455 0.766234
53 CA0 0.544304 0.753247
54 AD9 0.54321 0.753247
55 SA8 0.54321 0.873239
56 EEM 0.542169 0.849315
57 ACP 0.5375 0.753247
58 SFG 0.5375 0.826087
59 50T 0.5375 0.763158
60 HEJ 0.5375 0.773333
61 ATP 0.5375 0.773333
62 5FA 0.530864 0.773333
63 AQP 0.530864 0.773333
64 APC 0.530864 0.74359
65 APR 0.530864 0.773333
66 AR6 0.530864 0.773333
67 ANP 0.53012 0.753247
68 SAM 0.53012 0.875
69 SMM 0.529412 0.84
70 3AM 0.527027 0.756757
71 NEC 0.526316 0.823529
72 RBY 0.52439 0.74359
73 AGS 0.52439 0.75641
74 SAP 0.52439 0.75641
75 ADP PO3 0.52439 0.794521
76 ADV 0.52439 0.74359
77 5AL 0.52381 0.786667
78 54H 0.523256 0.705882
79 VMS 0.523256 0.705882
80 3AD 0.521739 0.863636
81 MTH 0.520548 0.984127
82 G5A 0.518072 0.678161
83 SAI 0.518072 0.830986
84 A5A 0.517647 0.722892
85 ME8 0.516484 0.797468
86 GAP 0.511905 0.753247
87 ACQ 0.511905 0.753247
88 T99 0.511905 0.766234
89 TAT 0.511905 0.766234
90 S7M 0.511628 0.824324
91 8QN 0.511364 0.786667
92 9ZD 0.511364 0.769231
93 9ZA 0.511364 0.769231
94 CC5 0.507463 0.876923
95 A3G 0.506494 0.828571
96 A3P 0.506329 0.77027
97 52H 0.505747 0.697674
98 NVA LMS 0.5 0.693182
99 7D5 0.5 0.714286
100 8X1 0.5 0.655556
101 53H 0.5 0.697674
102 ALF ADP 0.5 0.734177
103 ATF 0.5 0.74359
104 TSB 0.5 0.714286
105 MTP 0.5 0.828571
106 MAP 0.5 0.734177
107 ADP ALF 0.5 0.734177
108 DAL AMP 0.5 0.786667
109 25A 0.494382 0.773333
110 5SV 0.494382 0.759494
111 VO4 ADP 0.494253 0.763158
112 6YZ 0.494253 0.753247
113 ADP VO4 0.494253 0.763158
114 SRP 0.494253 0.74359
115 SSA 0.494253 0.678161
116 2AM 0.493333 0.746667
117 26A 0.492958 0.867647
118 PAJ 0.488889 0.75
119 LSS 0.488889 0.701149
120 A1R 0.488889 0.725
121 DSZ 0.488889 0.678161
122 ADQ 0.488889 0.753247
123 0UM 0.488889 0.810811
124 A3R 0.488889 0.725
125 3OD 0.483871 0.776316
126 AHX 0.483516 0.716049
127 62X 0.483516 0.815789
128 5CA 0.483146 0.678161
129 A22 0.483146 0.763158
130 A3T 0.481928 0.880597
131 2VA 0.481928 0.855072
132 RP1 0.480519 0.75
133 SP1 0.480519 0.75
134 3L1 0.478873 0.8
135 3D1 0.478873 0.8
136 OAD 0.478261 0.776316
137 LEU LMS 0.478261 0.693182
138 9X8 0.478261 0.779221
139 K15 0.478261 0.813333
140 OOB 0.477778 0.763158
141 GEK 0.477778 0.833333
142 A3S 0.47561 0.84058
143 OVE 0.474359 0.74026
144 P5A 0.473118 0.648352
145 PR8 0.473118 0.698795
146 NSS 0.472527 0.678161
147 4AD 0.472527 0.734177
148 AMO 0.472527 0.74359
149 2FA 0.472222 0.816901
150 6MD 0.472222 0.893939
151 NOC 0.471429 0.791045
152 NVA 2AD 0.470588 0.833333
153 A2P 0.469136 0.756757
154 2BA 0.469136 0.767123
155 CMP 0.469136 0.777778
156 9K8 0.468085 0.674157
157 PTJ 0.468085 0.759494
158 TXA 0.468085 0.766234
159 1ZZ 0.468085 0.731707
160 QQX 0.467532 0.714286
161 DLL 0.467391 0.763158
162 00A 0.467391 0.725
163 5F1 0.465753 0.782609
164 MYR AMP 0.463158 0.731707
165 3UK 0.462366 0.753247
166 ADP BMA 0.462366 0.753247
167 QQY 0.461538 0.723684
168 ACK 0.461538 0.739726
169 WAQ 0.457447 0.725
170 LAD 0.457447 0.707317
171 A A 0.457447 0.773333
172 B5V 0.457447 0.74359
173 GSU 0.457447 0.678161
174 KAA 0.457447 0.655556
175 PPS 0.454545 0.698795
176 B5Y 0.453608 0.75641
177 B5M 0.453608 0.75641
178 PAP 0.453488 0.76
179 BIS 0.452632 0.725
180 JB6 0.452632 0.746835
181 NB8 0.452632 0.716049
182 FYA 0.452632 0.763158
183 1DA 0.452055 0.878788
184 XAH 0.44898 0.690476
185 SO8 0.448276 0.869565
186 VRT 0.448276 0.84507
187 25L 0.447917 0.763158
188 KB1 0.447917 0.786667
189 4UV 0.444444 0.734177
190 9SN 0.443299 0.716049
191 V3L 0.443182 0.773333
192 LAQ 0.441176 0.710843
193 7D3 0.439024 0.696203
194 FA5 0.438776 0.74359
195 YAP 0.438776 0.734177
196 ATP A A A 0.438776 0.783784
197 8PZ 0.438776 0.678161
198 J1A 0.4375 0.740741
199 LPA AMP 0.436893 0.710843
200 J1C 0.435897 0.67033
201 7MD 0.435644 0.690476
202 AFH 0.435644 0.707317
203 GA7 0.435644 0.789474
204 4UU 0.435644 0.734177
205 J1B 0.434783 0.67033
206 YSA 0.434343 0.678161
207 4UW 0.432692 0.75
208 TXD 0.432692 0.746835
209 ARJ 0.432432 0.776119
210 MCF 0.432099 0.842857
211 GTA 0.431373 0.731707
212 TAD 0.431373 0.728395
213 KH3 0.431373 0.802632
214 4YB 0.431373 0.662921
215 TYR AMP 0.43 0.734177
216 AMP DBH 0.43 0.753247
217 IVH 0.428571 0.813333
218 AHZ 0.427184 0.731707
219 3NZ 0.427083 0.833333
220 7C5 0.425743 0.773333
221 G3A 0.425743 0.716049
222 2A5 0.425287 0.708861
223 7MC 0.424528 0.694118
224 AP0 0.424528 0.7375
225 TT8 0.423913 0.898551
226 YLP 0.423077 0.694118
227 48N 0.423077 0.7375
228 CNA 0.422018 0.74359
229 ARG AMP 0.421569 0.682353
230 AR6 AR6 0.421569 0.773333
231 G5P 0.421569 0.716049
232 ATR 0.420455 0.746667
233 101 0.419753 0.714286
234 D3Y 0.419355 0.816901
235 NXX 0.419048 0.74359
236 DND 0.419048 0.74359
237 6V0 0.419048 0.716049
238 NAX 0.419048 0.698795
239 NAI 0.419048 0.725
240 7D4 0.418605 0.696203
241 DQV 0.417476 0.763158
242 A A A 0.416667 0.763158
243 OMR 0.415094 0.722892
244 TXE 0.415094 0.725
245 649 0.415094 0.648352
246 D5M 0.414634 0.714286
247 DA 0.414634 0.714286
248 139 0.412844 0.698795
249 T5A 0.412844 0.694118
250 ADJ 0.412844 0.702381
251 YLB 0.411215 0.714286
252 YLC 0.411215 0.710843
253 F0P 0.411215 0.797297
254 8Q2 0.411215 0.655556
255 J1D 0.410714 0.628866
256 AYB 0.409091 0.705882
257 A2R 0.408602 0.763158
258 A4P 0.407407 0.659091
259 UP5 0.40566 0.734177
260 F2R 0.405405 0.674419
261 IOT 0.40367 0.666667
262 6CR 0.402597 0.805556
263 WSA 0.401869 0.686047
264 TYM 0.401869 0.74359
265 AF3 ADP 3PG 0.401869 0.707317
266 4TA 0.401786 0.702381
267 YLA 0.4 0.674419
Ligand no: 2; Ligand: HSL; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 HSL 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5HJM; Ligand: MTA; Similar sites found with APoc: 770
This union binding pocket(no: 1) in the query (biounit: 5hjm.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 4RVG TYD 1.42045
2 4RVG SAM 1.42045
3 1BXK NAD 1.42045
4 4YAC NAI 1.6835
5 3ZG6 APR 1.68919
6 5FWA J7C 1.70455
7 5XNC MTA 1.70455
8 6FP4 FAD 1.70455
9 2IID FAD 1.70455
10 2IID PHE 1.70455
11 6FP4 E1T 1.70455
12 4CNK FAD 1.70455
13 3GMB FAD 1.70455
14 5FUB SAH 1.78042
15 3EVG SAH 1.81818
16 3IID APR 1.89573
17 1ZEM NAD 1.9084
18 6CI9 NAP 1.9305
19 4Y9D NAI 1.96721
20 4A6D SAM 1.983
21 5MW4 5JU 1.98864
22 3QOX SAH 1.98864
23 3P9C SAH 1.98864
24 5JAQ NAI 1.98864
25 1D4D FAD 1.98864
26 2HQM FAD 1.98864
27 1GET NAP 1.98864
28 1GET FAD 1.98864
29 2Z3Y F2N 1.98864
30 1REO FAD 1.98864
31 4Z24 FAD 1.98864
32 3NTA FAD 1.98864
33 1WVG APR 1.98864
34 1ORR NAD 2.01729
35 4JNA FAD 2.05882
36 5E1M SAH 2.07469
37 5E1M PRO PRO LYS ARG ILE ALA 2.07469
38 2DPM SAM 2.11268
39 1RP0 AHZ 2.11268
40 2JK0 ASP 2.15385
41 5J60 FAD 2.1875
42 4ZRN NAD 2.24359
43 4ZRN UPG 2.24359
44 5WP5 SAH 2.27273
45 4UCI SAM 2.27273
46 5J5Z FAD 2.27273
47 3GF4 FAD 2.27273
48 1GPE FAD 2.27273
49 3QVP FAD 2.27273
50 5VN0 FAD 2.27273
51 5VN0 NAI 2.27273
52 3AYI FAD 2.27273
53 3AYI HCI 2.27273
54 3GF4 UPG 2.27273
55 1MO9 KPC 2.27273
56 1MO9 FAD 2.27273
57 2Q1S NAI 2.27273
58 3WMX NAD 2.27273
59 3PFG SAM 2.28137
60 3PFG TLO 2.28137
61 6GAR FAD 2.29226
62 2OOR TXP 2.29885
63 5OJI ISN 2.30769
64 5OJI NAP 2.30769
65 2PWY SAH 2.32558
66 5TWB FAD 2.32558
67 2WSB NAD 2.3622
68 1QZZ SAM 2.40642
69 6BWL NAD 2.43902
70 1EDO NAP 2.45902
71 4TQG NDP 2.47678
72 3F8D FAD 2.47678
73 5XLX SAH 2.48227
74 4RPL 3UC 2.50627
75 4RPL FAD 2.50627
76 2XVM SAH 2.51256
77 5O42 NAD 2.55474
78 5O42 9JW 2.55474
79 5O42 BGC 2.55474
80 1KYQ NAD 2.55474
81 1FP2 SAH 2.55682
82 1XDS SAM 2.55682
83 5KOK SAH 2.55682
84 1FP2 HMO 2.55682
85 5KOK S9T 2.55682
86 5KOK R9T 2.55682
87 5HSA FAS 2.55682
88 5FJN BE2 2.55682
89 5FJN FAD 2.55682
90 4HA6 FAD 2.55682
91 2NVK FAD 2.55682
92 2VVM FAD 2.55682
93 2R4J FAD 2.55682
94 2R4J 13P 2.55682
95 2VVL FAD 2.55682
96 3NKS FAD 2.55682
97 5I39 FAD 2.55682
98 3ICT FAD 2.55682
99 3RHJ NAP 2.55682
100 3ICS FAD 2.55682
101 3ICR FAD 2.55682
102 1RKX NAD 2.55682
103 5UAO FAD 2.55682
104 3ICS ADP 2.55682
105 3TKA SAM 2.59366
106 3MAG SAH 2.60586
107 2O07 SPD 2.63158
108 2O07 MTA 2.63158
109 4FWE FAD 2.63819
110 5A3B APR 2.64026
111 2DTX BMA 2.65152
112 2A14 SAH 2.6616
113 1TZJ A3B 2.66272
114 1R6D NAD 2.67062
115 1R6D DAU 2.67062
116 3G2O SAM 2.67559
117 1G60 SAM 2.69231
118 3MCT SAH 2.6936
119 5KMS NAD 2.71605
120 5KMS FAD 2.71605
121 1GEG NAD 2.73438
122 4PIO SAH 2.78638
123 4PIO AVI 2.78638
124 4IRP UDP 2.78884
125 5GWX SAR 2.8169
126 5GWX SAM 2.8169
127 2JAH NDP 2.83401
128 1F3L SAH 2.84091
129 5X62 SAH 2.84091
130 1ZK7 FAD 2.84091
131 5WGR FAD 2.84091
132 1I2B UPG 2.84091
133 1I2B NAD 2.84091
134 1I2B USQ 2.84091
135 3KLJ FAD 2.84091
136 1Y8Q ATP 2.84091
137 3K7M FAD 2.84091
138 3EYA FAD 2.84091
139 3NYC FAD 2.84091
140 3NYC IAR 2.84091
141 1RLZ NAD 2.84091
142 5TTJ FAD 2.84091
143 4BJZ P3A 2.84091
144 4BJZ FAD 2.84091
145 4XQC 13D 2.84091
146 1UAY ADN 2.89256
147 3CGB FAD 2.91667
148 5EJ2 NAD 2.92208
149 4ZCC FAD 2.97619
150 4ZCC NAI 2.97619
151 5Y1G AKB 3.04878
152 5Y1G NAD 3.04878
153 5Z75 NAD 3.0581
154 3O7W SAM 3.06122
155 2Q7V FAD 3.07692
156 2AE2 PTO 3.07692
157 2AE2 NAP 3.07692
158 1Q0S SAH 3.0888
159 5K7U SAM 3.11111
160 5ICE SAH 3.125
161 5ICE 2H4 3.125
162 3SSO SAH 3.125
163 3S5W FAD 3.125
164 5BJX NAD 3.125
165 5BJX UDP 3.125
166 2CDU FAD 3.125
167 5G3U FDA 3.125
168 1GPM CIT 3.125
169 2AQJ TRP 3.125
170 2AQJ FAD 3.125
171 1ZBQ NAD 3.125
172 5MZI FYK 3.125
173 5MZI FAD 3.125
174 2CDU ADP 3.125
175 2E5V FAD 3.125
176 5G3U ITW 3.125
177 5Y77 FAD 3.125
178 1TPY SAH 3.13589
179 1WG8 SAM 3.15789
180 4XUC 43G 3.21101
181 4XUC SAM 3.21101
182 2EWM NAD 3.21285
183 3QJ4 FAD 3.21637
184 5KVA SAM 3.23741
185 2JAP NDP 3.23887
186 2WA2 SAM 3.26087
187 1RJD SAM 3.29341
188 5NMX FAD 3.29412
189 5NMX NAP 3.29412
190 5IL1 SAM 3.30189
191 3FUU ADN 3.32103
192 2PZM NAD 3.33333
193 2PZM UDP 3.33333
194 4QTU SAM 3.36538
195 2GDZ NAD 3.37079
196 5DLY 5D7 3.38346
197 5DLY SAH 3.38346
198 1FP1 SAH 3.40909
199 5ERG SAM 3.40909
200 2RAB NAD 3.40909
201 2RAB FAD 3.40909
202 5OJ7 AR6 3.40909
203 2Q28 ADP 3.40909
204 1I8T FAD 3.40909
205 6H3O FAD 3.40909
206 3UCL FAD 3.40909
207 3UCL CYH 3.40909
208 3UCL NAP 3.40909
209 1XSE NDP 3.40909
210 5DF1 NAP 3.40909
211 5DF1 58X 3.40909
212 6ER9 FAD 3.40909
213 6ER9 NAP 3.40909
214 6C8R SAH 3.43008
215 6C8R EQV 3.43008
216 3LE7 ADE 3.44828
217 2FK8 SAM 3.45912
218 4QAR ADE 3.48259
219 3VC1 SAH 3.52564
220 3VC1 GST 3.52564
221 4FN4 NAD 3.54331
222 3P2E SAH 3.55556
223 1S7G APR 3.55731
224 1S7G NAD 3.55731
225 6FDF SAH 3.59281
226 6DUB SAH 3.6036
227 1BDB NAD 3.61011
228 6F9Q NAD 3.67647
229 3JWH SAH 3.68664
230 5EEH P9P 3.69318
231 5EEH SAH 3.69318
232 4D7E FAD 3.69318
233 1PJS NAD 3.69318
234 6F97 FAD 3.69318
235 1QO8 FAD 3.69318
236 5X7Q GLC GLC GLC GLC 3.69318
237 2XVF FAD 3.69318
238 5ZYN FAD 3.69318
239 1GTE FAD 3.69318
240 4D04 FAD 3.69318
241 4D04 NAP 3.69318
242 5X7Q GLC GLC GLC 3.69318
243 4TXI FAD 3.69318
244 4IV9 FAD 3.69318
245 2BRY FAD 3.69318
246 5GM1 SAH 3.7037
247 3OFK SAH 3.7037
248 4DCM SAM 3.73333
249 3LST SAH 3.73563
250 4N49 SAM 3.73832
251 5UFN SAH 3.78151
252 3C3Y SAH 3.79747
253 3N5O GSH 3.82979
254 5E9W SAH 3.84615
255 4M52 FAD 3.86266
256 4M52 M52 3.86266
257 2A8X FAD 3.87931
258 1QH9 LAC 3.87931
259 4NTC FAD 3.8806
260 3ZV6 NAD 3.91459
261 3ZV6 4HB 3.91459
262 3EVF SAH 3.97112
263 3EVF GTA 3.97112
264 4FC7 COA 3.97112
265 4FC7 NAP 3.97112
266 1SQF SAM 3.97727
267 2EG5 SAH 3.97727
268 2JB2 FAD 3.97727
269 2JB2 PHE 3.97727
270 3HDY FAD 3.97727
271 3HDY GDU 3.97727
272 3HDY FDA 3.97727
273 4KGD FAD 3.97727
274 4KGD TDP 3.97727
275 1M2K APR 3.97727
276 2XVE FAD 3.97727
277 1RSG FAD 3.97727
278 1V5F FAD 3.97727
279 1V5F TPP 3.97727
280 3CTY FAD 3.97727
281 5KOX RFP 3.97727
282 5KOX FAD 3.97727
283 2RGO FAD 3.97727
284 1C0I FAD 3.97727
285 1C0I BE2 3.97727
286 2C7G ODP 3.97727
287 2C7G FAD 3.97727
288 5LW0 AR6 3.97727
289 4G5H NAP 3.97727
290 4G5H UD7 3.97727
291 2YVF NAD 3.97727
292 2YVF FAD 3.97727
293 1KEW NAD 3.97727
294 5N5D SAM 3.9823
295 4GUT FAD 4.03226
296 4HSU FAD 4.03226
297 4GUS FAD 4.03226
298 4URF NAD 4.03226
299 1LVW TYD 4.0678
300 1GZ6 NAI 4.07523
301 4ITU NAI 4.08922
302 4ITU 1HS 4.08922
303 1BC5 SAH 4.08922
304 6C5B SAH 4.10557
305 3HCH RSM 4.10959
306 1IY8 NAD 4.11985
307 3OU2 SAH 4.12844
308 1U7T TDT 4.21456
309 3WDM ADN 4.21456
310 3I53 SAH 4.21687
311 4NEC SAH 4.26136
312 5WP4 SAH 4.26136
313 5U8U FAD 4.26136
314 5BVA FAD 4.26136
315 3LAD FAD 4.26136
316 2ZWA SAH 4.26136
317 3GDN HBX 4.26136
318 3GDN FAD 4.26136
319 1SB8 UD2 4.26136
320 1SB8 NAD 4.26136
321 4RSL FAD 4.26136
322 3E1T FAD 4.26136
323 5GSN FAD 4.26136
324 5GSN NAP 4.26136
325 5GSN MMZ 4.26136
326 5JCM NAD 4.26136
327 5JCM FAD 4.26136
328 5JCM ISD 4.26136
329 6EL3 NAP 4.26136
330 1EU1 MGD 4.26136
331 4D5G FAD 4.26136
332 4D5G TPP 4.26136
333 2V6G NAP 4.26136
334 3LCV SAM 4.27046
335 1OC2 NAD 4.31034
336 1OC2 TDX 4.31034
337 2JHP SAH 4.34783
338 4YJK URA 4.36508
339 3CGD FAD 4.375
340 3CGD COA 4.375
341 3CGD NAD 4.375
342 2BOS GLA GAL GLC NBU 4.41176
343 2BOS GLA GAL GLC 4.41176
344 1DL5 SAH 4.4164
345 6ECW SAH 4.44444
346 3NUG NAD 4.45344
347 1YC5 NCA 4.47154
348 4BUZ OCZ 4.47154
349 4BUZ OAD 4.47154
350 4BUZ NAD 4.47154
351 3T7S SAM 4.47761
352 5DM1 5D7 4.49438
353 5DM1 SAH 4.49438
354 3HVJ 705 4.52489
355 5E8J SAH 4.54545
356 4ONQ SFG 4.54545
357 2WPF WPF 4.54545
358 2WPF FAD 4.54545
359 1X87 NAD 4.54545
360 4HXY NDP 4.54545
361 6D6Y SAH 4.54545
362 5EB4 FAD 4.54545
363 5BUK FAD 4.54545
364 2C5A GDC 4.54545
365 2C5A NAD 4.54545
366 3LU1 NAD 4.54545
367 4BV6 FAD 4.54545
368 4U8P FDA 4.54545
369 3IHG FAD 4.54545
370 4U8P UDP 4.54545
371 4USR FAD 4.54545
372 5YJI SAH 4.57746
373 5YJI 8WO 4.57746
374 5YJF SAH 4.57746
375 5YJF 8WO 4.57746
376 4J36 1HR 4.57831
377 4J36 FAD 4.57831
378 3FXU TSU 4.59016
379 4FZV SAM 4.60251
380 4R6W PC 4.65116
381 4R6W SAH 4.65116
382 1Z3C SA8 4.69799
383 4CS9 AMP 4.7619
384 2CFC NAD 4.8
385 5DNK SAH 4.82955
386 1BZL FAD 4.82955
387 6F7L FAD 4.82955
388 1H82 FAD 4.82955
389 1H82 GZZ 4.82955
390 4J56 FAD 4.82955
391 4EIP FAD 4.82955
392 6GKV SAH 4.8433
393 1R18 SAH 4.84582
394 3GEG NAD 4.8583
395 2P41 SAH 4.91803
396 2XYQ SAH 4.91803
397 4CQM NAP 4.91803
398 4YUW 4JU 4.93421
399 4YUW S4M 4.93421
400 4L2I FAD 4.94297
401 3LKZ SFG 4.98442
402 1EJ0 SAM 5
403 4YMH SAH 5
404 3SJU NDP 5.01792
405 6AIN FAD 5.02392
406 5MGZ SAH 5.08475
407 5Y80 IRE 5.11182
408 1I1N SAH 5.11364
409 3S1S SAH 5.11364
410 2IVD FAD 5.11364
411 4AT0 FAD 5.11364
412 5TS5 FAD 5.11364
413 4MOP 2H5 5.11364
414 4TM3 FAD 5.11364
415 4II2 ATP 5.11364
416 2YY7 NAD 5.12821
417 5BSZ SAH 5.2
418 5M58 SAH 5.21739
419 1L1E SAH 5.22648
420 2EXX NAP 5.22876
421 2GAG NAD 5.2381
422 1YXM ADE 5.28053
423 6ECU SAH 5.37975
424 1NFQ NAI 5.38462
425 3GU3 SAH 5.39773
426 3PT9 SAH 5.39773
427 3GWZ SAH 5.39773
428 5MPT SAH 5.39773
429 3GXO SAH 5.39773
430 3SQP FAD 5.39773
431 1ZGA SAH 5.39773
432 4NTD FAD 5.39773
433 5T67 JHZ 5.39773
434 4MO2 FDA 5.39773
435 5T67 SAH 5.39773
436 4MO2 FAD 5.39773
437 4USQ FAD 5.39773
438 2GV8 FAD 5.39773
439 1VQW FAD 5.39773
440 5F2K SAH 5.39773
441 5F2K OCA 5.39773
442 3AXB FAD 5.39773
443 2GVC FAD 5.39773
444 4XFR CIT 5.39773
445 3AXB PRO 5.39773
446 3LZW NAP 5.42169
447 3LZW FAD 5.42169
448 6GAS FAD 5.43807
449 2PXX SAH 5.5814
450 1NJR XYL 5.6338
451 3C6K MTA 5.68182
452 3NDJ SAH 5.68182
453 3NDJ JHZ 5.68182
454 5MBX SP5 5.68182
455 5MBX FAD 5.68182
456 3C6K SPD 5.68182
457 3RUV ANP 5.68182
458 2AG5 NAD 5.69106
459 1IM8 SAI 5.7377
460 6BQ6 TER 5.74018
461 5MIT NAP 5.8104
462 5MIT FAD 5.8104
463 2GN4 UD1 5.81395
464 2GN4 NDP 5.81395
465 6HOY TSN 5.96026
466 6HOY AR6 5.96026
467 4KIB SAH 5.96591
468 4C4A SAH 5.96591
469 1YBH FAD 5.96591
470 2YG3 FAD 5.96591
471 5BRT FAD 5.96591
472 5BRT CH9 5.96591
473 4REP FAD 5.96591
474 4X9M FAD 5.96591
475 1RYI GOA 5.96591
476 2Y6Q I7T 5.96591
477 2Y6Q FAD 5.96591
478 1RYI FAD 5.96591
479 5N0J FAD 5.98291
480 2ZFU SAH 6.04651
481 2VT3 ATP 6.04651
482 2ZIF SAM 6.06061
483 1XKQ NDP 6.07143
484 3FPZ AHZ 6.13497
485 3H8V ATP 6.16438
486 4M73 SAH 6.23145
487 4M73 M72 6.23145
488 1U2Z SAH 6.25
489 3TKY SAH 6.25
490 5FTW SAH 6.25
491 1GY8 NAD 6.25
492 2C31 ADP 6.25
493 2C31 TZD 6.25
494 1NAA 6FA 6.25
495 1NAA ABL 6.25
496 1YY5 FAD 6.25
497 3ABI NAD 6.25
498 3GD4 NAD 6.26223
499 3GD4 FAD 6.26223
500 1DJL NAP 6.28019
501 1N2X SAM 6.31229
502 5CUQ NSC 6.36704
503 1XCL SAH 6.38298
504 2WK1 SAH 6.38298
505 3CBG SAH 6.46552
506 5GWT SIN 6.47482
507 5GWT NAD 6.47482
508 1VR0 3SL 6.47773
509 3RKR NAP 6.48855
510 2AOT SAH 6.50685
511 1JQD SAH 6.50685
512 1JQD HSM 6.50685
513 1UWK NAD 6.53409
514 1UWK URO 6.53409
515 4EUE NAI 6.53409
516 4E70 N7I 6.53409
517 1Q9I TEO 6.53409
518 1Q9I FAD 6.53409
519 4JDR FAD 6.53409
520 4C3Y FAD 6.53409
521 4C3Y ANB 6.53409
522 3NTD FAD 6.53409
523 3UOY NAP 6.53409
524 3UOY FAD 6.53409
525 1NW5 SAM 6.58307
526 1KPG SAH 6.62021
527 5E72 SAM 6.6474
528 1NV8 MEQ 6.69014
529 1NV8 SAM 6.69014
530 5ULP KB1 6.71642
531 1G8K MGD 6.76692
532 2UYQ SAM 6.77419
533 3L9W AMP 6.77966
534 3L9W GSH 6.77966
535 1UDB NAD 6.80473
536 1UDB UFG 6.80473
537 1XHC FAD 6.81199
538 5YF1 SFG 6.81818
539 3U4C NDP 6.81818
540 5YF1 8V0 6.81818
541 2WET FAD 6.81818
542 6CZ7 MGD 6.81818
543 4AP3 NAP 6.81818
544 4AP3 FAD 6.81818
545 2QA1 FAD 6.81818
546 6ECT SAM 6.85358
547 4BLW SAH 6.92042
548 4BLW AMP 6.92042
549 4J7U NAP 6.94444
550 4J7U YTZ 6.94444
551 5W7K SAH 7.05128
552 1D4O NAP 7.06522
553 1XTP SAI 7.08661
554 1Z6Z NAP 7.0922
555 5FA5 MTA 7.10227
556 3X0D SAH 7.10227
557 1PN0 FAD 7.10227
558 1PN0 IPH 7.10227
559 2DKH FAD 7.10227
560 2DKH 3HB 7.10227
561 3FRH SAH 7.11462
562 3VYW SAM 7.14286
563 4X60 SFG 7.14286
564 4X60 3XV 7.14286
565 2BGM NAJ 7.19424
566 5JGL SAM 7.26644
567 4GQB 0XU 7.26744
568 6EQS BV8 7.27273
569 3RIY NAD 7.32601
570 3DXY SAM 7.33945
571 3A28 NAD 7.36434
572 1FEC FAD 7.38636
573 1COY FAD 7.38636
574 4YNU FAD 7.38636
575 4YNU LGC 7.38636
576 1COY AND 7.38636
577 3X0V FAD 7.38636
578 5HZ9 5M8 7.40741
579 3LXD FAD 7.46988
580 6B92 SAH 7.48299
581 4POO SAM 7.5
582 1P1C SAH 7.53769
583 5ZW3 SAH 7.55556
584 4PNE SAH 7.61589
585 3G89 SAM 7.63052
586 5O4J 9KH 7.66423
587 5O4J PJL 7.66423
588 5O4J SAH 7.66423
589 3AB1 FAD 7.67045
590 4LHD GLY 7.67045
591 5WS9 AMP 7.67045
592 6ARJ BW4 7.73639
593 6ARJ SAH 7.73639
594 5DX0 SFG 7.73639
595 5DWQ SFG 7.73639
596 1XHL NDP 7.74411
597 2PT9 2MH 7.78816
598 2PT9 S4M 7.78816
599 3GCZ SAM 7.80142
600 4M37 SAH 7.87172
601 4M38 SAH 7.87172
602 5K0A FAD 7.87879
603 1V59 NAD 7.95455
604 1V59 FAD 7.95455
605 4EMI NAD 7.95455
606 4EMI FAD 7.95455
607 4EMJ FAD 7.95455
608 1ELI PYC 7.96915
609 5G3L SIA 8.08081
610 3LCC SAH 8.08511
611 5W7R SAH 8.15851
612 5W7R 9Z7 8.15851
613 4KRG SAH 8.23864
614 4YRY FAD 8.23864
615 1LVL FAD 8.23864
616 4YRY NAD 8.23864
617 1LVL NAD 8.23864
618 5TUF FAD 8.23864
619 5TUF TDC 8.23864
620 1O97 FAD 8.33333
621 1O97 AMP 8.33333
622 5W7M SAH 8.33333
623 4KRI SAH 8.52273
624 1T36 ORN 8.52273
625 4K5S PM0 8.52273
626 4K5S FAD 8.52273
627 1LSS NAD 8.57143
628 3RFV 15L 8.61423
629 3RFV NAI 8.61423
630 3ZNN 4WL 8.64553
631 3ZNN FAD 8.64553
632 3WGT QSC 8.64553
633 3WGT FAD 8.64553
634 3QFA FAD 8.67052
635 6GFK SAH 8.76494
636 2HNK SAH 8.78661
637 2EFJ SAH 8.80682
638 2I7C AAT 8.83392
639 1QAN SAH 9.01639
640 4RDH AMP 9.02778
641 5JJR SAH 9.09091
642 2VPY PCI 9.09091
643 1YQZ FAD 9.09091
644 3CH6 311 9.09091
645 3CH6 NAP 9.09091
646 1E1M NAP 9.09091
647 1E1M FAD 9.09091
648 2RGJ FAD 9.09091
649 2VPY MGD 9.09091
650 3BXO SAM 9.20502
651 2WPB ZZI 9.21053
652 4BWL MN9 9.21053
653 1H5R THM 9.21502
654 1H5S TMP 9.21502
655 4YAG NAI 9.34256
656 4AZW SAM 9.375
657 1KYZ SAH 9.375
658 1KYZ FER 9.375
659 4MIG G3F 9.375
660 3DUW SAH 9.41704
661 4IWN GEK 9.60699
662 3MQ2 SAH 9.63303
663 5OC1 FAD 9.65909
664 3M6W SAM 9.65909
665 1KPH SAH 9.7561
666 5TVI O8N 9.78261
667 3A4T SFG 9.85401
668 1E6E FAD 10.1562
669 4YSX FAD 10.2837
670 3RNM FAD 10.3448
671 3FPF TNA 10.4027
672 3FPF MTA 10.4027
673 1JQ3 AAT 10.473
674 2Q1W NAD 10.5105
675 2EJU SAH 10.5114
676 3TLJ SAH 10.5114
677 2JJQ SAH 10.5114
678 5THY SAH 10.5114
679 5F8F SFG 10.5114
680 1ZQ9 SAM 10.5114
681 5THZ SAH 10.5114
682 2IV2 MGD 10.5114
683 3Q87 SAM 10.5882
684 1FLJ GSH 10.7692
685 1VE3 SAM 11.0132
686 1E3W NAD 11.1111
687 5U19 SAH 11.1437
688 5U19 827 11.1437
689 1E6W NAD 11.1538
690 3GRU AMP 11.1864
691 3U31 NAD 11.3793
692 6BVE PGA 11.4286
693 3FZG SAM 11.5
694 2BZG SAH 11.6379
695 6DEN FAD 11.6477
696 6DEN TP9 11.6477
697 6DEN G8A 11.6477
698 4LWP SAH 11.9318
699 2NXE SAM 11.9318
700 1T9D P25 11.9318
701 1T9D FAD 11.9318
702 5WKC FAD 11.9318
703 1T9D PYD 11.9318
704 1T9D 1MM 11.9318
705 4J1Q NDP 12.2845
706 3H2B SAH 12.3153
707 3ELW GP3 12.3333
708 3ELW SAM 12.3333
709 3GDH SAH 12.4481
710 4NBW NAD 12.4514
711 4DSG FAD 12.5
712 4DSG UDP 12.5
713 4Y30 SAH 12.5356
714 4Y30 49L 12.5356
715 2PX8 SAH 12.6394
716 4K26 NDP 12.6812
717 4K26 SFF 12.6812
718 2BD0 NAP 12.7049
719 5JCA FAD 12.7841
720 5JCA NDP 12.7841
721 3AD8 NAD 12.8713
722 5LOG SAH 12.8755
723 1L3I SAH 13.0208
724 2FR1 NDP 13.0682
725 3EGI ADP 13.1068
726 4NBU NAI 13.2
727 3QWI NAP 13.3333
728 4B63 NAP 13.3523
729 4B63 ORN 13.3523
730 4B63 FAD 13.3523
731 1G55 SAH 13.4111
732 3BGD SAH 13.4615
733 3BGD PM6 13.4615
734 2OBF SAH 13.8408
735 2OBF F83 13.8408
736 1KNR FAD 13.9205
737 3G5S FAD 13.9205
738 2B4Q NAP 14.1304
739 5FA8 SAM 14.2857
740 4YMZ 13P 14.3426
741 2NUO BGC 14.7541
742 1EFV FAD 14.902
743 1EFV AMP 14.902
744 4OBW SAM 15.1751
745 2Q46 NAP 15.415
746 1PNO NAP 16.1111
747 1JG3 ADN 16.1702
748 4DMG SAM 16.1932
749 1I9G SAM 16.4286
750 5JE0 SAH 16.5992
751 5JE0 AZ8 16.5992
752 1OAA OAA 16.6023
753 5BW4 SAM 17.9775
754 3DMH SAM 18.75
755 3DMH GMP 18.75
756 1ZOS MTM 19.1304
757 2HMT NAI 19.4444
758 3VSE SAH 20.7386
759 1XG5 NAP 20.7885
760 5L95 AMP 21.25
761 2F5Z FAD 21.875
762 1WY7 SAH 24.6377
763 6F5Z SAH 27.8689
764 3MB5 SAM 29.4118
765 5DX8 SFG 31.5789
766 5DXA SFG 31.5789
767 2VDV SAM 33.7398
768 5DX1 SFG 36.8421
769 3A27 SAM 45.5882
770 3A25 SAM 47.5083
Pocket No.: 2; Query (leader) PDB : 5HJM; Ligand: HSL; Similar sites found with APoc: 24
This union binding pocket(no: 2) in the query (biounit: 5hjm.bio1) has 7 residues
No: Leader PDB Ligand Sequence Similarity
1 5K4W NAI 1.86916
2 5K4W THR 1.86916
3 6FL8 TIY 2.27273
4 6FL8 ADP 2.27273
5 3X44 PUS 2.71084
6 5DRB 5FJ 2.74914
7 1VL0 NAI 3.08219
8 1J0D 5PA 3.22581
9 1I8T FAD 3.40909
10 5I7A 68Q 3.68098
11 5E9W SAH 3.84615
12 1F2U ATP 4.05405
13 2JHP SAH 4.34783
14 6ECW SAH 4.44444
15 5E8J SAH 4.54545
16 5NV8 TRH 5.96591
17 5FAG PPI 5.96591
18 3B2Q ATP 7.10227
19 5JGL SAM 7.26644
20 5W7M SAH 8.33333
21 3AJM 4IP 8.4507
22 1PUJ GNP 9.57447
23 4BQS ADP 11.9318
24 4BQS K2Q 11.9318
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