Receptor
PDB id Resolution Class Description Source Keywords
5HPY 2.4 Å NON-ENZYME: MOBILE CRYSTAL STRUCTURE OF RHOA.GDP.MGF3-IN COMPLEX WITH HUMAN MYO RHOGAP DOMAIN HOMO SAPIENS COMPLEX RHO GTPASES RHOGAP GENE REGULATION-SIGNALING PROTCOMPLEX
Ref.: NONCANONICAL MYO9B-RHOGAP ACCELERATES RHOA GTP HYDR A DUAL-ARGININE-FINGER MECHANISM J.MOL.BIOL. V. 428 3043 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MGF F:201;
B:201;
Invalid;
Invalid;
none;
none;
submit data
81.3 F3 Mg F[Mg-...
MG B:202;
F:204;
F:203;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
GDP B:203;
F:202;
Valid;
Valid;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5HPY 2.4 Å NON-ENZYME: MOBILE CRYSTAL STRUCTURE OF RHOA.GDP.MGF3-IN COMPLEX WITH HUMAN MYO RHOGAP DOMAIN HOMO SAPIENS COMPLEX RHO GTPASES RHOGAP GENE REGULATION-SIGNALING PROTCOMPLEX
Ref.: NONCANONICAL MYO9B-RHOGAP ACCELERATES RHOA GTP HYDR A DUAL-ARGININE-FINGER MECHANISM J.MOL.BIOL. V. 428 3043 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 61 families.
1 5HPY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 55 families.
1 5HPY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 39 families.
1 5HPY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5HPY; Ligand: GDP; Similar sites found: 429
This union binding pocket(no: 1) in the query (biounit: 5hpy.bio2) has 20 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3LN9 FLC 0.01363 0.40771 None
2 3IIJ ADP 0.00004037 0.52472 2.22222
3 3UIE ANP 0.00005714 0.50441 2.7027
4 2QZ4 ADP 0.0001213 0.4895 2.7027
5 2GDJ ANP 0.0002538 0.48647 3.01724
6 3ZS9 ADP ALF 0.0001179 0.42541 3.01724
7 2WOJ ADP ALF 0.0001422 0.42085 3.01724
8 1VHT BA3 0.001204 0.44402 3.21101
9 3EWA ANP 0.0001337 0.4998 3.24324
10 3BFV ADP 0.0001929 0.49218 3.24324
11 4ZNL BEF ADP 0.0001992 0.48542 3.24324
12 4V03 ADP 0.0002 0.47958 3.24324
13 2CHG ANP 0.0005004 0.45163 3.24324
14 1W5T ANP 0.001749 0.41304 3.24324
15 1W5T ADP 0.003921 0.41264 3.24324
16 5WRJ A3P 0.01174 0.40047 3.24324
17 3TK1 GDP 0.00000002914 0.69851 3.44828
18 3E70 GDP 0.0000449 0.51565 3.44828
19 1M2Z BOG 0.01293 0.40672 3.44828
20 1YQT ADP 0.00008247 0.53013 3.78378
21 2ZFI ADP 0.00003764 0.52617 3.78378
22 3FWY ADP 0.000048 0.496 3.78378
23 4RZ3 ADP 0.0007764 0.44332 3.78378
24 4FRZ ADP 0.000006125 0.46149 4.31034
25 5MZN ADP 0.002423 0.45015 4.31034
26 1D2N ANP 0.0026 0.40604 4.31034
27 2FH5 GTP 0.000000001462 0.65879 4.32432
28 1JI0 ATP 0.00006082 0.53095 4.32432
29 5L3V GDP 0.00002311 0.52234 4.32432
30 5LTJ ADP 0.00008511 0.50267 4.32432
31 1H65 GDP 0.000007322 0.49899 4.32432
32 3VX3 ADP 0.0003503 0.45066 4.32432
33 3P4X ADP 0.00006887 0.45046 4.32432
34 2GK6 ADP 0.002681 0.44793 4.32432
35 5LTJ BEF 0.006762 0.43937 4.32432
36 3ZQ6 ADP ALF 0.0002786 0.41065 4.32432
37 3KTA AP5 0.0006668 0.45084 4.62428
38 4QM7 GTP 0.0001214 0.50182 4.67836
39 4GOX A3P 0.001802 0.40213 4.74138
40 2IXE ATP 0.0005868 0.42376 4.79705
41 2WJG GDP 0.00000001885 0.68424 4.86486
42 2C77 GNP 0.00000005807 0.62974 4.86486
43 2C78 GNP 0.00000004693 0.58451 4.86486
44 2OG2 MLI 0.00009163 0.53433 4.86486
45 4ZKD GDP 0.0000001207 0.52484 4.86486
46 3B9Q MLI 0.0001692 0.5158 4.86486
47 3BOS CDP 0.00008321 0.50967 4.86486
48 4D81 ADP 0.0002322 0.47126 4.86486
49 3DZD ADP 0.0007226 0.44928 4.86486
50 1IN4 ADP 0.0006302 0.43832 4.86486
51 3KJI ADP 0.02091 0.40477 4.86486
52 2W58 ADP 0.000001773 0.63286 4.9505
53 1LVG ADP 0.00003162 0.54529 5.05051
54 4MKF AP5 0.004808 0.43722 5.06912
55 4BQS ADP 0.0001128 0.50335 5.11364
56 1D2E GDP 0.00000007189 0.62767 5.17241
57 2XTN GTP 0.000003476 0.50372 5.17241
58 1SKQ GDP 0.00000002094 0.6935 5.40541
59 4LC1 GDP 0.000000115 0.64661 5.40541
60 2CBZ ATP 0.000001253 0.64122 5.40541
61 1PUJ GNP 0.0000001064 0.62008 5.40541
62 5KUT GDP 0.000000009704 0.61821 5.40541
63 4M9Q GNP 0.00000008465 0.57618 5.40541
64 3ZFD ANP 0.000003598 0.55918 5.40541
65 4YMU ATP 0.00007876 0.51781 5.40541
66 2DPY ADP 0.0001343 0.51359 5.40541
67 4HSE ADP 0.00005267 0.51241 5.40541
68 4NON GDP 0.0000001307 0.51056 5.40541
69 5LB3 ADP 0.0001482 0.50431 5.40541
70 1XKV ATP 0.0007019 0.45471 5.40541
71 1IHU AF3 0.0001321 0.44883 5.40541
72 5VGR GDP 0.0007657 0.44358 5.40541
73 1IHU ADP 0.0001434 0.4395 5.40541
74 1XPJ TLA 0.01788 0.42364 5.55556
75 2WIC GNP 0.0000003226 0.61579 5.60345
76 5XDR ADP 0.0005045 0.46656 5.60345
77 4IEE AGS 0.001369 0.45686 5.60345
78 5K5Z ANP 0.0003027 0.42283 5.60345
79 1QXA GLY GLY GLY 0.03128 0.40059 5.60345
80 1OE0 TTP 0.01071 0.40527 5.65217
81 4E03 ADP 0.0001002 0.45877 5.82524
82 3CNL GNP 0.0000001239 0.65557 5.94595
83 4R98 GNH 0.000000522 0.61516 5.94595
84 5X40 ACP 0.0006634 0.45468 5.94595
85 1FEC FAD 0.01441 0.42061 5.94595
86 2WJH GDP 0.0000001196 0.57988 6.0241
87 2WJH FLC 0.00002055 0.49615 6.0241
88 1GOJ ADP 0.0000005894 0.65478 6.03448
89 3Q9L ATP 0.0007409 0.4442 6.03448
90 2FSH ANP 0.004659 0.43068 6.03448
91 4OI4 ATP 0.001523 0.40109 6.08696
92 2FNA ADP 0.0004476 0.42882 6.46552
93 5IRR GSP 0.0000003281 0.55167 6.48649
94 4QOS ADP 0.000445 0.46374 6.48649
95 3COB ADP 0.000002508 0.46241 6.48649
96 3DKP ADP 0.00173 0.44653 6.48649
97 5M7P ADP 0.0006665 0.43748 6.48649
98 5MEX SZZ 0.01341 0.41294 6.48649
99 5MEX PAP 0.007559 0.40213 6.48649
100 3X27 TRP 0.01897 0.40057 6.48649
101 3LRE ADP 0.000002693 0.61768 6.89655
102 3VMF GTP 0.00000007094 0.54182 6.89655
103 2JLR ANP 0.0002951 0.46662 7.02703
104 2BEK ATP 0.0002399 0.4409 7.02703
105 4JLV ADP 0.003854 0.43474 7.02703
106 3CV2 OXL 0.02456 0.40906 7.02703
107 3FVQ ATP 0.0003831 0.43911 7.24234
108 2IYL GDP 0.00003122 0.53006 7.39437
109 5MVR ADP 0.0000672 0.51411 7.40741
110 3T34 GDP 0.00001239 0.48499 7.56757
111 2ZJ5 ADP 0.006789 0.43066 7.56757
112 3BER AMP 0.01604 0.40006 7.56757
113 2WHX ADP 0.00003023 0.55321 7.75862
114 4R43 GDP 0.000148 0.49769 7.75862
115 1G3Q ADP 0.0003061 0.4767 7.75862
116 4XGU ADP 0.001019 0.43818 7.75862
117 4XTR ADP 0.0001226 0.46853 7.8341
118 4XTR ATP 0.0001276 0.44329 7.8341
119 4XVU ATP 0.0001484 0.44095 7.8341
120 4KFU ACP 0.00001063 0.45724 8.01887
121 4R2I ANP 0.00087 0.47262 8.09524
122 4DCT GDP 0.000000002925 0.71122 8.10811
123 5CK5 GDP 0.00000008586 0.66339 8.10811
124 4H1V GNP 0.000003694 0.54454 8.10811
125 4LYA ATP 0.00004023 0.51787 8.10811
126 1FP6 ADP 0.00007905 0.49212 8.10811
127 2ZPA ADP 0.0006322 0.43855 8.10811
128 3IO3 ADP 0.01352 0.41764 8.10811
129 5M04 GDP 0.00000008039 0.66479 8.18966
130 1DAR GDP 0.0000001094 0.64767 8.18966
131 5L3W GDP 0.00003882 0.51206 8.18966
132 4PX9 ADP 0.000453 0.48047 8.18966
133 5L3S GNP 0.00004888 0.45163 8.18966
134 3BFX A3P 0.003296 0.40986 8.18966
135 5L3S G 0.01956 0.40958 8.18966
136 4KVA GTP 0.000002765 0.40554 8.18966
137 3PQC GDP 0.00000002563 0.65713 8.20513
138 5BQ5 ADP BEF 0.000178 0.48189 8.46561
139 2FAH GDP 0.0001588 0.47862 8.62069
140 4PJ3 ANP 0.004476 0.41395 8.62069
141 2OZE AGS 0.01893 0.41059 8.62069
142 2D2F ADP 0.0002382 0.51373 8.64865
143 5GJC ATP 0.00009437 0.50705 8.64865
144 1U0J ADP 0.000807 0.46814 8.64865
145 1UKZ ADP 0.004406 0.43109 8.64865
146 3WXM GTP 0.00000006058 0.6405 9.05172
147 1SQ5 ADP 0.00006456 0.50828 9.05172
148 4AG5 ADP 0.00002476 0.55721 9.18919
149 2HF9 GSP 0.000002977 0.48975 9.18919
150 1M7G ADX 0.00046 0.47379 9.18919
151 1M7G AV2 0.00001453 0.47071 9.18919
152 2PL3 ADP 0.0007702 0.46914 9.18919
153 1M7G ADP 0.0007458 0.46106 9.18919
154 2GWH A3P 0.002794 0.41907 9.18919
155 1YRB GDP 0.00000002965 0.6448 9.48276
156 2XAU ADP 0.0006312 0.45681 9.48276
157 1Z6T ADP 0.0001536 0.47398 9.72973
158 5I34 GDP 0.0005216 0.46588 9.72973
159 5H56 TYD 0.0009223 0.45837 9.74359
160 5H56 ADP 0.0009223 0.45837 9.74359
161 3A1S GDP 0.0000002553 0.62054 9.91379
162 3EZ2 ADP 0.00008266 0.51677 9.91379
163 1SVI GDP 0.000000001311 0.75265 10.2703
164 1XX6 ADP 0.00006781 0.53588 10.2703
165 3B5J 12D 0.00005891 0.53165 10.2703
166 3B7G ANP 0.0005168 0.46607 10.2703
167 5GVR LMR 0.000992 0.46346 10.2703
168 3TBK ANP 0.001414 0.46196 10.2703
169 1NY5 ADP 0.0005943 0.44838 10.2703
170 5J1J ANP 0.0001742 0.43705 10.2703
171 4U00 ADP 0.000009094 0.42568 10.2703
172 2HCJ GDP 0.000000001978 0.74386 10.3448
173 3U6B GDP 0.000000003966 0.72901 10.3448
174 3U6K GDP 0.000000007274 0.70404 10.3448
175 5JBQ GDP 0.000000008607 0.70054 10.3448
176 4G5G GDP 0.000000008774 0.70014 10.3448
177 2BVN GNP 0.00000007784 0.62612 10.3448
178 1D8T GDP 0.00000001179 0.60141 10.3448
179 4PC3 GDP 0.0000002887 0.60075 10.3448
180 1WDT GTP 0.000007087 0.52118 10.3448
181 2VF7 ADP 0.0006601 0.4611 10.3448
182 4TTQ ATP 0.0001322 0.50004 10.6977
183 1BO4 COA 0.01606 0.40005 10.7143
184 1OXV ANP 0.00008868 0.43752 10.7759
185 2Z5F A3P 0.003166 0.40338 10.7759
186 3DC4 ADP 0.00004307 0.53852 10.8108
187 1G6H ADP 0.000006631 0.60107 11.2069
188 1YTM ATP 0.0002682 0.4467 11.2069
189 2QN6 GDP 0.000000002292 0.74072 11.3514
190 3WY9 GDP 0.000000004491 0.72636 11.3514
191 3WYA GDP 0.000000006604 0.70605 11.3514
192 4RD0 GDP 0.000000007483 0.61368 11.3514
193 2PZE ATP 0.000009443 0.58735 11.3514
194 1OYY AGS 0.001462 0.45005 11.3514
195 1R0X ATP 0.0003106 0.4231 11.3514
196 4WEI GLC GAL 0.01418 0.41886 11.3514
197 2X7I CIT 0.01039 0.40915 11.3514
198 4YDS ATP 0.00001372 0.5636 11.4035
199 3RC3 ANP 0.005723 0.42628 11.6379
200 3H4S ADP 0.000001478 0.62825 11.8519
201 1TQ4 GDP 0.0000002589 0.56811 11.8919
202 5IFS ADP 0.0003385 0.44425 11.8919
203 1F5N GNP 0.0002345 0.41264 11.8919
204 1L2T ATP 0.0005751 0.41048 11.8919
205 3QKT ANP 0.0009687 0.40314 11.8919
206 1ION ADP 0.000308 0.47103 12.069
207 1JJ7 ADP 0.000004125 0.61411 12.4324
208 1G7C 5GP 0.00000148 0.59349 12.4324
209 5HR5 ADP 0.0003011 0.46125 12.4324
210 2B8W ALF 5GP 0.000192 0.42899 12.4324
211 5MX4 HPA 0.02758 0.40113 12.4324
212 5J1S ATP 0.001288 0.40036 12.4324
213 4WOP CTP 0.001311 0.41835 12.4444
214 5TSH ADP 0.00007652 0.53067 12.5
215 5TSH ANP 0.00005278 0.51914 12.5
216 5FHD ADP ALF 0.00005879 0.47157 12.5
217 5FTB ANP 0.0003778 0.46698 12.5
218 1JWY GDP 0.000003879 0.55047 12.931
219 1JWY ADP 0.000009218 0.54777 12.931
220 1JJV ATP 0.0001244 0.52015 13.1068
221 4CVN ADP 0.0000152 0.56134 13.1387
222 4A4Z ANP 0.006534 0.41885 13.3621
223 2IS6 ADP 0.0001687 0.49497 13.5135
224 2OBM ADP 0.000691 0.4852 13.5135
225 5L3R GCP 0.0000737 0.44619 13.5135
226 1KO8 6PG 0.001055 0.42946 13.7143
227 2AWN ADP 0.000001114 0.64954 14.0541
228 4WZ6 ATP 0.00003152 0.55251 14.0541
229 1AQU A3P 0.003316 0.41582 14.0541
230 1FNN ADP 0.0003568 0.44902 14.2241
231 5GOE GDP 0.0000001801 0.6185 14.5946
232 5FG3 GDP 0.000000002434 0.61297 14.5946
233 2XTZ GSP 0.00000006584 0.55004 14.5946
234 3NHB ADP 0.0000292 0.55402 14.6552
235 3RLF ANP 0.0004311 0.42229 14.6552
236 2ZPT A3P 0.02011 0.41733 14.6552
237 4P3Y GDP 0.000000006899 0.59688 14.8352
238 1NJF AGS 0.0005164 0.45755 15.0862
239 1NJF ADP 0.0004254 0.45701 15.0862
240 3DEF GDP 0.000005428 0.54396 15.1351
241 3ITJ CIT 0.02945 0.40062 15.1351
242 1G7S GDP 0.0000001275 0.63464 15.5172
243 2QEN ADP 0.0001086 0.48056 15.5172
244 4PPF FLC 0.000008603 0.58842 15.6757
245 3QF7 ANP 0.001869 0.41851 16
246 5G41 AP5 0.006315 0.43542 16.1435
247 1WF3 GNP 0.0000002504 0.51561 16.2162
248 4FCW ADP 0.0006839 0.42752 16.2162
249 1KK1 GNP 0.00000002226 0.6922 16.7568
250 3EC1 GDP 0.0000004591 0.60864 16.7568
251 1ZCB GDP 0.000000372 0.60496 16.7568
252 3AB3 GDP 0.0000002462 0.60205 16.7568
253 4BAS GNP 0.000001509 0.57003 16.7568
254 1Y3A GDP 0.000001057 0.52642 16.7568
255 1GP2 GDP 0.000002943 0.50973 16.7568
256 3CX8 GSP 0.0000002085 0.50921 16.7568
257 2ODE ALF GDP 0.0000002869 0.50417 16.7568
258 1BH2 GSP 0.000000353 0.50275 16.7568
259 1SVK ALF GDP 0.000000191 0.50088 16.7568
260 5E5U MLI 0.003807 0.43017 17.0854
261 1W0J ADP 0.00006495 0.49592 17.2414
262 1W0J ADP BEF 0.0001817 0.46115 17.2414
263 2CK3 ANP 0.0001903 0.46043 17.2414
264 2CK3 ADP 0.0002124 0.43351 17.2414
265 1MKY GDP 0.000000001844 0.73258 17.2973
266 2OFW ADX 0.001062 0.46616 17.2973
267 1NRJ GTP 0.000000781 0.55187 17.4312
268 3ZIA ADP 0.00008424 0.47736 17.4603
269 3ZIA ATP 0.00003709 0.47518 17.4603
270 4J0Q GDP 0.000000007016 0.71684 17.8378
271 1HTW ADP 0.0000552 0.46861 18.3544
272 1TAD GDP 0.0000002719 0.50403 18.3784
273 1TAD ALF 0.0000002719 0.50403 18.3784
274 4U60 SIA GAL NGA 0.01114 0.42346 18.3784
275 4U60 SIA 0.01181 0.42202 18.3784
276 5H67 ATP 0.006716 0.41397 18.75
277 4LPS GDP 0.00000004344 0.65648 18.9189
278 3W5J GDP 0.000002978 0.61067 18.9189
279 2ZR9 DTP 0.0002001 0.49142 18.9189
280 1GOT GDP 0.000002568 0.52066 19.1781
281 4LJ9 ACP 0.002123 0.44227 19.4595
282 2X77 GDP 0.00000002225 0.67005 20.1058
283 1CS4 GSP 0.0000002808 0.5146 20.5405
284 1AZT GSP 0.0000001784 0.51158 20.5405
285 4IDN GNP 0.0001459 0.44762 20.5405
286 1QHH ATP 0.01022 0.40541 20.8696
287 3A4M ADP 0.00001164 0.56719 21.0811
288 4HI0 GDP 0.000002815 0.52844 21.0811
289 2V7Q ADP 0.00004599 0.522 21.2121
290 2V7Q ATP 0.00003737 0.51282 21.2121
291 1YZG GDP 0.0000001511 0.63119 21.7877
292 1ZJ6 G3D 0.00000009642 0.6403 22.1622
293 1R6B ADP 0.0001658 0.48913 22.1622
294 4YS0 ADP 0.002636 0.42017 22.1622
295 2A5F GTP 0.0000002769 0.5365 22.8571
296 5KDO GDP 0.000002539 0.53091 22.973
297 2VOH CIT 0.01705 0.42412 23.0769
298 5IRN ADP 0.0001196 0.48411 23.2432
299 2C04 GCP 0.001067 0.4373 23.2432
300 5EE5 GTP 0.000000045 0.58669 23.9766
301 3PCR GTP 0.0000004092 0.54049 24.0741
302 1MR3 G3D 0.0000003108 0.56096 24.3094
303 4KBF AMP 0.005722 0.42628 24.3243
304 3N5C GDP 0.0000000954 0.65051 24.6914
305 4TMZ GSP 0.000000008348 0.59859 24.8649
306 4NCN GTP 0.000000008659 0.59728 24.8649
307 1Y63 ADP 0.0000999 0.50587 25.5435
308 2D7D ADP 0.002429 0.40222 27.5
309 5KSP GDP 0.000000006512 0.69498 27.5676
310 5KSZ GCP 0.00000003602 0.65039 27.5676
311 2RCN GDP 0.000000001917 0.73177 28.1081
312 1KSH GDP 0.00000001562 0.65491 28.1081
313 1F6B GDP 0.000001521 0.58433 28.1081
314 3DOE GTP 0.00000009501 0.56224 28.1081
315 2GJ8 ALF GDP 0.0000001212 0.52655 28.4884
316 3H86 AP5 0.00806 0.42005 29.1667
317 5HCN GCP 0.00000006587 0.64803 29.7297
318 4KAX GTP 0.000000131 0.56978 30.1775
319 1R4A GNP 0.00000005331 0.56093 31.3725
320 2W83 GTP 0.0000001442 0.55683 32.1212
321 3AQ4 GDP 0.0000002182 0.62373 32.6087
322 1FQJ GDP 0.0000001729 0.55578 32.973
323 1FQK GDP 0.000000418 0.543 32.973
324 1FQJ ALF 0.0002358 0.50707 32.973
325 1FQK ALF 0.001578 0.46856 32.973
326 1UPT GTP 0.0000000977 0.57293 33.3333
327 3T1O GDP 0.00000031 0.60775 33.5135
328 3T12 GDP ALF 0.0000003029 0.55556 33.5135
329 4V0K GDP 0.000001281 0.50805 33.7278
330 4YLG GDP 0.0000001922 0.60048 34.104
331 3M1I GTP 0.000000000607 0.60538 34.5946
332 3WYF GTP 0.000000001184 0.58477 34.5946
333 2ZEJ GDP 0.000003828 0.47492 34.7826
334 3GJX GTP 0.0000000005916 0.73419 35.1351
335 3GJ4 GDP 0.000000003956 0.71671 35.1351
336 3GJ7 GDP 0.000000005047 0.71164 35.1351
337 3GJ8 GDP 0.000000009542 0.68723 35.1351
338 3GJ5 GDP 0.00000001162 0.68324 35.1351
339 1ZD9 GDP 0.00000006236 0.60746 35.1351
340 3WYG GTP 0.000000001168 0.58515 35.1648
341 4HAT GNP 0.0000000004632 0.74196 35.6757
342 5UWT GNP 0.000000000459 0.73918 35.6757
343 3GJ0 GDP 0.000000004529 0.7139 35.6757
344 3GJ3 GDP 0.000000006748 0.7056 35.6757
345 5BXQ GDP 0.000000003926 0.63495 35.6757
346 5DIF GNP 0.0000000003286 0.61317 35.6757
347 5UWU GNP 0.0000000003541 0.61214 35.6757
348 5UWO GNP 0.0000000003539 0.61209 35.6757
349 5UWQ GNP 0.0000000003649 0.61185 35.6757
350 5UWW GNP 0.0000000003682 0.61153 35.6757
351 5UWJ GNP 0.0000000003954 0.61084 35.6757
352 5UWI GNP 0.0000000004005 0.61075 35.6757
353 5UWR GNP 0.0000000004581 0.60886 35.6757
354 5UWH GNP 0.0000000004752 0.60854 35.6757
355 5DHF GNP 0.0000000004854 0.60819 35.6757
356 1IBR GNP 0.000000000581 0.60574 35.6757
357 5UWP GNP 0.0000000004624 0.59705 35.6757
358 5DI9 GNP 0.0000000005208 0.59564 35.6757
359 5UWS GNP 0.0000000005217 0.59561 35.6757
360 1J2J GTP 0.00000002726 0.5824 36.1446
361 2J59 GTP 0.00000007826 0.56603 36.1446
362 1O3Y GTP 0.0000001687 0.55589 36.1446
363 1S9D GDP 0.0000003891 0.61199 37.1951
364 1RE0 GDP 0.00000005022 0.56933 37.1951
365 1M2O GNP 0.0000002211 0.5288 37.2973
366 1WA5 GTP 0.0000000007603 0.55989 37.5
367 4B47 GDP 0.000000005717 0.72121 37.8378
368 2OM2 GDP 0.000003198 0.52624 38.8889
369 2G77 GDP 0.0000000002536 0.72596 38.9189
370 2G77 AF3 0.0004809 0.49187 38.9189
371 1Z06 GNP 0.0000000005264 0.63031 39.4595
372 4ZI2 GNP 0.00000009333 0.57371 40.5263
373 4GOJ GNP 0.00000009985 0.57374 40.7407
374 2QTV GNP 0.000001323 0.51326 41.3174
375 2CJW GDP 0.000000001378 0.73865 41.6216
376 3BC1 GNP 0.00000000107 0.60723 41.6216
377 5DI3 GNP 0.0000001069 0.57325 41.6216
378 3Q72 GNP 0.0000000002799 0.6445 42.1687
379 2BME GNP 0.0000000006336 0.72979 43.2432
380 3RWO GDP 0.000000002144 0.70593 43.2432
381 1FZQ GDP 0.00000005803 0.66084 43.6464
382 3CPJ GDP 0.000000003572 0.66324 43.7838
383 3E5H GNP 0.0000000006623 0.61515 43.8202
384 1OIX GDP 0.0000000001314 0.63581 44.3243
385 1OIV GDP 0.000000005238 0.68843 44.8649
386 1X1R GDP 0.000000002024 0.58452 44.9438
387 2A5J GDP 0.0000000001597 0.75773 45.4054
388 2BCG GDP 0.000000002148 0.66701 45.4054
389 2F9L GDP 0.000000002067 0.61926 45.4054
390 3Q85 GNP 0.0000000024 0.6274 45.5621
391 1Z0F GDP 0.0000000003757 0.75286 45.8101
392 1Z0K GTP 0.0000000009435 0.6345 45.9302
393 1VG9 GDP 0.0000000003804 0.75261 45.9459
394 1VG8 GNP 0.0000000004136 0.74123 45.9459
395 1VG0 GDP 0.00000000173 0.69981 45.9459
396 1VG1 GDP 0.0000000002121 0.68404 45.9459
397 3TKL GTP 0.00000000006639 0.65968 45.9459
398 1YZN GNP 0.00000000009194 0.62809 45.9459
399 4D0G GTP 0.0000000008694 0.65032 46.2857
400 5JCZ GDP 0.0000000004346 0.69577 46.3687
401 3T5G GDP 0.000000003837 0.69476 46.4088
402 2HT6 GDP 0.0000000009004 0.76066 46.5517
403 4LX0 BEF GDP 0.0000000002538 0.75084 46.8927
404 5SZH GNP 0.00000000008819 0.77164 47.027
405 1EK0 GNP 0.0000000008018 0.60787 47.0588
406 5UQW GDP 0.000000011 0.58206 47.0899
407 1XTQ GDP 0.00000003463 0.57567 47.4576
408 1S8F GDP 0.000000002017 0.57142 47.4576
409 4DSU GDP 0.000000003365 0.57791 47.5676
410 2A9K GDP 0.0000000008715 0.7026 47.5936
411 1Z0J GTP 0.0000000003616 0.60842 47.6471
412 2HV8 GTP 0.0000000003197 0.62206 47.6744
413 1TU3 GNP 0.0000000002359 0.74914 47.9532
414 4C4P GNP 0.0000000007377 0.59864 47.9769
415 3NKV GNP 0.00000000002603 0.65937 48
416 2Y8E GNP 0.0000000002417 0.62895 48.0447
417 3SFV GDP 0.0000000007379 0.7134 48.0663
418 4DKX GDP 0.00000000002742 0.82012 48.1081
419 1D5C GDP 0.0000000005708 0.71061 48.1481
420 3MJH GTP 0.00000000007626 0.64209 48.2143
421 1R2Q GNP 0.0000000002493 0.54 48.2353
422 1KY3 GDP 0.000000005757 0.65376 48.3517
423 2D7C GTP 0.0000000006104 0.73052 48.503
424 1ZC3 GNP 0.0000000001296 0.76406 48.5714
425 1UAD GNP 0.00000000006156 0.77545 49.1429
426 2EFE GNH 0.000000005996 0.67575 49.1713
427 1KAO GDP 0.00000001193 0.65309 49.7006
428 1YVD GNP 0.0000000002675 0.62505 49.7041
429 5WDR GNP 0.0000000000849 0.62829 49.7076
Pocket No.: 2; Query (leader) PDB : 5HPY; Ligand: GDP; Similar sites found: 4
This union binding pocket(no: 2) in the query (biounit: 5hpy.bio1) has 20 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2XMY CDK 0.04486 0.40502 6.03448
2 1SR7 MOF 0.01196 0.40966 7.32759
3 4X1Z FUC GAL NDG 0.0248 0.4064 9.18919
4 5AHO TLA 0.0275 0.40098 10.3448
Feedback