Receptor
PDB id Resolution Class Description Source Keywords
5I3B 2.2 Å EC: 1.14.18.1 CRYSTAL STRUCTURE OF TYROSINASE FROM BACILLUS MEGATERIUM WIT CONFIGURATION B OF HYDROQUINONE INHIBITOR IN THE ACTIVE SIT BACILLUS MEGATERIUM DI-COPPER OXIDASE OXIDOREDUCTASE
Ref.: THE UNRAVELLING OF THE COMPLEX PATTERN OF TYROSINAS INHIBITION. SCI REP V. 6 34993 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ZN A:302;
B:302;
B:304;
A:301;
B:301;
 Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
 none;
none;
none;
none;
none;
 submit data
65.409 Zn [Zn+2...
HQE B:303;
A:303;
 Valid;
Valid;
 none;
none;
 Kd = 9 uM
110.111 C6 H6 O2 c1cc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6QXD 2.32 Å EC: 1.14.18.1 CRYSTAL STRUCTURE OF TYROSINASE FROM BACILLUS MEGATERIUM WIT INHIBITOR IN THE ACTIVE SITE. BACILLUS MEGATERIUM TYROSINASE INHIBITOR LIGAND OXIDOREDUCTASE
Ref.: EXPLOITING THE 1-(4-FLUOROBENZYL)PIPERAZINE FRAGMEN DEVELOPMENT OF NOVEL TYROSINASE INHIBITORS AS ANTI-MELANOGENIC AGENTS: DESIGN, SYNTHESIS, STRUCTU INSIGHTS AND BIOLOGICAL PROFILE. EUR.J.MED.CHEM. V. 178 380 2019
Members (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 6QXD ic50 = 0.96 uM JKB C18 H17 F N4 O5 c1cc(ccc1C....
2 4P6R - TYR C9 H11 N O3 c1cc(ccc1C....
3 4P6S - DAH C9 H11 N O4 c1cc(c(cc1....
4 4P6T - YRL C8 H10 O2 c1cc(ccc1C....
5 5I3B Kd = 9 uM HQE C6 H6 O2 c1cc(ccc1O....
6 5I3A Kd = 9 uM HQE C6 H6 O2 c1cc(ccc1O....
7 3NQ1 - KOJ C6 H6 O4 C1=C(OC=C(....
8 6EI4 - B5N C19 H21 F N2 O Cc1ccccc1C....
70% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 6QXD ic50 = 0.96 uM JKB C18 H17 F N4 O5 c1cc(ccc1C....
2 4P6R - TYR C9 H11 N O3 c1cc(ccc1C....
3 4P6S - DAH C9 H11 N O4 c1cc(c(cc1....
4 4P6T - YRL C8 H10 O2 c1cc(ccc1C....
5 5I3B Kd = 9 uM HQE C6 H6 O2 c1cc(ccc1O....
6 5I3A Kd = 9 uM HQE C6 H6 O2 c1cc(ccc1O....
7 3NQ1 - KOJ C6 H6 O4 C1=C(OC=C(....
8 6EI4 - B5N C19 H21 F N2 O Cc1ccccc1C....
50% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 6QXD ic50 = 0.96 uM JKB C18 H17 F N4 O5 c1cc(ccc1C....
2 4P6R - TYR C9 H11 N O3 c1cc(ccc1C....
3 4P6S - DAH C9 H11 N O4 c1cc(c(cc1....
4 4P6T - YRL C8 H10 O2 c1cc(ccc1C....
5 5I3B Kd = 9 uM HQE C6 H6 O2 c1cc(ccc1O....
6 5I3A Kd = 9 uM HQE C6 H6 O2 c1cc(ccc1O....
7 3NQ1 - KOJ C6 H6 O4 C1=C(OC=C(....
8 6EI4 - B5N C19 H21 F N2 O Cc1ccccc1C....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: HQE; Similar ligands found: 18
No: Ligand ECFP6 Tc MDL keys Tc
1 HQE 1 1
2 4HB 0.5625 0.8125
3 FPN 0.529412 0.647059
4 BML 0.529412 0.647059
5 PCR 0.529412 0.785714
6 IOL 0.529412 0.647059
7 4CH 0.529412 0.647059
8 A8K 0.473684 0.684211
9 H8N 0.45 0.6875
10 IPH 0.4375 0.769231
11 FCR 0.428571 0.611111
12 H3Z 0.428571 0.6875
13 4VP 0.428571 0.733333
14 HBA 0.428571 0.857143
15 PHB 0.409091 0.8125
16 DBE 0.409091 0.764706
17 H48 0.409091 0.8125
18 2OH 0.409091 0.65
Similar Ligands (3D)
Ligand no: 1; Ligand: HQE; Similar ligands found: 803
No: Ligand Similarity coefficient
1 PXY 1.0000
2 2MH 1.0000
3 4JU 1.0000
4 PLQ 1.0000
5 LG4 1.0000
6 25R 1.0000
7 DA1 1.0000
8 4HS 0.9970
9 4JN 0.9951
10 CYH 0.9813
11 4XX 0.9781
12 CXL 0.9775
13 1MC 0.9751
14 2IM 0.9732
15 HAI 0.9724
16 V1L 0.9722
17 FPI 0.9707
18 25T 0.9698
19 282 0.9692
20 FPY 0.9692
21 TDR 0.9687
22 MCT 0.9679
23 TH0 0.9668
24 URF 0.9666
25 AMC 0.9655
26 4AP 0.9651
27 1DH 0.9651
28 ICP 0.9650
29 MBN 0.9646
30 PYD 0.9645
31 XBZ 0.9644
32 1PT 0.9644
33 GXE 0.9642
34 3AP 0.9642
35 ECE 0.9638
36 HVK 0.9637
37 2AP 0.9637
38 WBU 0.9637
39 WOT 0.9636
40 A1U 0.9636
41 5MH 0.9634
42 QOS 0.9633
43 HRZ 0.9633
44 A2Q 0.9632
45 4HO 0.9629
46 LGA 0.9628
47 275 0.9627
48 XYD 0.9626
49 4CL 0.9616
50 2AC 0.9614
51 TMZ 0.9614
52 JZ2 0.9612
53 34A 0.9610
54 J1Z 0.9610
55 XYP 0.9609
56 5UC 0.9608
57 9PO 0.9606
58 4ZE 0.9602
59 2MP 0.9600
60 MWM 0.9597
61 4JO 0.9596
62 HBX 0.9590
63 HT4 0.9586
64 8CL 0.9585
65 LXC 0.9578
66 4JJ 0.9578
67 DEN 0.9577
68 43M 0.9574
69 5JC 0.9574
70 MZG 0.9570
71 TM7 0.9570
72 PYF 0.9570
73 BZF 0.9569
74 HYN 0.9567
75 CEJ 0.9565
76 27Y 0.9564
77 0CT 0.9558
78 GVH 0.9558
79 NBE 0.9558
80 2YU 0.9557
81 MZW 0.9557
82 BP9 0.9557
83 0R1 0.9551
84 IND 0.9550
85 ABN 0.9549
86 4JP 0.9548
87 4JL 0.9547
88 MPI 0.9542
89 BZI 0.9542
90 SYN 0.9542
91 FBA 0.9540
92 LZ1 0.9540
93 BR9 0.9533
94 7EX 0.9533
95 MWJ 0.9526
96 XIX 0.9526
97 PY7 0.9525
98 VAL 0.9516
99 C2B 0.9515
100 TTO 0.9513
101 IUR 0.9510
102 DMG 0.9508
103 TMT 0.9508
104 TLD 0.9507
105 8H8 0.9503
106 MZ0 0.9503
107 RSF 0.9498
108 MAK 0.9484
109 FYU 0.9479
110 NK 0.9479
111 KIV 0.9471
112 OHG 0.9466
113 Y8I 0.9465
114 CRS 0.9465
115 HHN 0.9464
116 MLA 0.9459
117 LDU 0.9458
118 4JM 0.9455
119 IDM 0.9452
120 2KT 0.9452
121 L60 0.9440
122 280 0.9438
123 HGW 0.9438
124 PIH 0.9433
125 93B 0.9430
126 PRO 0.9422
127 1AN 0.9418
128 92Z 0.9417
129 6AI 0.9416
130 0R0 0.9415
131 CAQ 0.9415
132 8LG 0.9411
133 1MR 0.9410
134 HMH 0.9409
135 93Q 0.9407
136 IDH 0.9406
137 HIU 0.9404
138 BZX 0.9402
139 24T 0.9401
140 14O 0.9399
141 XYS 0.9396
142 JZ0 0.9396
143 2K4 0.9395
144 NVI 0.9392
145 5H1 0.9391
146 BEW 0.9390
147 L89 0.9389
148 F60 0.9387
149 JAE 0.9385
150 APY 0.9385
151 MLI 0.9385
152 RCO 0.9384
153 P2D 0.9382
154 ICC 0.9381
155 FP2 0.9375
156 270 0.9375
157 CYS 0.9375
158 ZZT 0.9374
159 NPO 0.9373
160 3ZQ 0.9372
161 JZ3 0.9371
162 R2B 0.9370
163 5MI 0.9369
164 HPY 0.9368
165 MAE 0.9368
166 AX7 0.9367
167 P92 0.9366
168 FOA 0.9360
169 PYJ 0.9358
170 URA 0.9356
171 5MB 0.9356
172 OXE 0.9355
173 2MI 0.9354
174 2CH 0.9352
175 DGY 0.9347
176 BEZ 0.9345
177 938 0.9345
178 11S 0.9345
179 TH7 0.9343
180 PYG 0.9339
181 DSN 0.9337
182 BAM 0.9336
183 BEN 0.9334
184 2AF 0.9333
185 3PY 0.9333
186 JZ9 0.9330
187 4XR 0.9329
188 B24 0.9328
189 LG3 0.9327
190 3MC 0.9327
191 HTS 0.9326
192 CYT 0.9324
193 NBZ 0.9322
194 3CH 0.9321
195 MLM 0.9317
196 DUC 0.9315
197 ES9 0.9312
198 AHR 0.9312
199 EDG 0.9311
200 OAA 0.9311
201 284 0.9311
202 76X 0.9307
203 E60 0.9307
204 H4N 0.9305
205 FK1 0.9299
206 6X8 0.9294
207 QUZ 0.9292
208 ABV 0.9292
209 23W 0.9290
210 1AB 0.9290
211 BVF 0.9289
212 FFP 0.9287
213 KG7 0.9284
214 GMN 0.9284
215 NIO 0.9283
216 9CL 0.9283
217 3FA 0.9283
218 PZA 0.9281
219 HGQ 0.9281
220 NCA 0.9281
221 NSP 0.9280
222 MRY 0.9279
223 PYC 0.9276
224 THR 0.9276
225 9X7 0.9275
226 MBD 0.9274
227 C5J 0.9273
228 24B 0.9273
229 YCP 0.9267
230 NPY 0.9266
231 6PC 0.9266
232 DTU 0.9266
233 PCA 0.9261
234 26D 0.9261
235 1DU 0.9259
236 NTN 0.9258
237 2PC 0.9254
238 OXQ 0.9248
239 8GF 0.9246
240 8NY 0.9245
241 0TR 0.9240
242 DXX 0.9236
243 LG5 0.9236
244 TFB 0.9235
245 2C9 0.9234
246 FLM 0.9233
247 KSW 0.9232
248 TM4 0.9226
249 FUM 0.9225
250 SIN 0.9225
251 2MY 0.9224
252 TP5 0.9224
253 23A 0.9222
254 HMU 0.9219
255 265 0.9218
256 VGL 0.9215
257 XM0 0.9215
258 SER 0.9214
259 273 0.9211
260 LMR 0.9210
261 BVG 0.9210
262 JIF 0.9209
263 FUL 0.9208
264 40O 0.9207
265 UNU 0.9207
266 JBN 0.9205
267 HSL 0.9202
268 PAB 0.9201
269 ARB 0.9200
270 RIP 0.9198
271 1Y6 0.9194
272 HBD 0.9193
273 F81 0.9193
274 3CE 0.9187
275 0MK 0.9185
276 MMZ 0.9184
277 RIB 0.9184
278 R8A 0.9183
279 H3M 0.9182
280 BVC 0.9180
281 RSO 0.9180
282 MB3 0.9178
283 KOJ 0.9178
284 BAQ 0.9173
285 PBZ 0.9172
286 6MH 0.9168
287 PZM 0.9167
288 826 0.9166
289 BE7 0.9165
290 AMT 0.9163
291 SW7 0.9163
292 TZC 0.9162
293 YHO 0.9162
294 7CZ 0.9161
295 4MA 0.9159
296 JFD 0.9159
297 4H2 0.9158
298 HX3 0.9157
299 Z82 0.9156
300 C21 0.9153
301 GOL 0.9152
302 HVQ 0.9150
303 2CM 0.9150
304 P72 0.9146
305 3MT 0.9144
306 HY3 0.9144
307 174 0.9143
308 ALO 0.9142
309 5AC 0.9141
310 35C 0.9140
311 286 0.9140
312 MZY 0.9140
313 DFU 0.9139
314 HEW 0.9137
315 CIG 0.9137
316 GAG 0.9136
317 1MZ 0.9136
318 3TR 0.9135
319 4MZ 0.9133
320 FUC 0.9132
321 GBD 0.9132
322 60P 0.9131
323 5MP 0.9131
324 B3R 0.9131
325 JZ5 0.9128
326 3DM 0.9127
327 MMU 0.9126
328 FQI 0.9125
329 2HA 0.9124
330 M3T 0.9124
331 MR3 0.9124
332 1WG 0.9122
333 7MH 0.9121
334 1CB 0.9120
335 278 0.9120
336 3MH 0.9117
337 M1A 0.9115
338 T6C 0.9114
339 JBE 0.9114
340 URP 0.9113
341 SAL 0.9112
342 FAN 0.9111
343 BE2 0.9111
344 2MZ 0.9111
345 PBC 0.9110
346 HOW 0.9109
347 2CK 0.9108
348 4SV 0.9108
349 ATQ 0.9105
350 JZ1 0.9103
351 3U4 0.9101
352 AC6 0.9101
353 285 0.9096
354 67N 0.9096
355 ABE 0.9095
356 F05 0.9093
357 2AI 0.9091
358 GBL 0.9090
359 ABA 0.9090
360 HLR 0.9088
361 SS1 0.9088
362 SMV 0.9086
363 FLA 0.9086
364 QSC 0.9085
365 AC0 0.9084
366 DUB 0.9081
367 717 0.9080
368 14J 0.9078
369 MEU 0.9075
370 JAB 0.9075
371 JZ6 0.9074
372 9EW 0.9074
373 5KX 0.9073
374 9TY 0.9068
375 HSE 0.9067
376 MLT 0.9066
377 5NU 0.9066
378 1XX 0.9066
379 HHQ 0.9065
380 7WG 0.9062
381 NEQ 0.9061
382 DTI 0.9060
383 PM6 0.9058
384 M58 0.9058
385 HPA 0.9056
386 ES6 0.9055
387 ES4 0.9054
388 BTE 0.9054
389 SVN 0.9048
390 TBP 0.9048
391 R8S 0.9047
392 B53 0.9046
393 HX2 0.9045
394 ADE 0.9043
395 150 0.9040
396 G6D 0.9039
397 5WV 0.9037
398 5CU 0.9037
399 SS2 0.9036
400 IMR 0.9033
401 TLA 0.9033
402 FCA 0.9030
403 36R 0.9030
404 BP1 0.9029
405 BYZ 0.9029
406 GLC 0.9027
407 DFB 0.9025
408 0RW 0.9024
409 9DA 0.9024
410 2CQ 0.9022
411 F4Z 0.9022
412 P3K 0.9019
413 5VM 0.9019
414 64K 0.9017
415 2EZ 0.9016
416 TC7 0.9016
417 1WD 0.9016
418 10L 0.9014
419 ET2 0.9014
420 ES3 0.9012
421 CLW 0.9010
422 UY7 0.9009
423 4M0 0.9009
424 4DX 0.9007
425 YAN 0.9007
426 T2C 0.9006
427 3SK 0.9005
428 7WA 0.9005
429 VGD 0.9004
430 6MP 0.9002
431 DMI 0.9002
432 BHA 0.9001
433 4AX 0.9000
434 LER 0.9000
435 DOB 0.8999
436 SWD 0.8999
437 45C 0.8997
438 PYZ 0.8991
439 69O 0.8986
440 UGC 0.8981
441 FA0 0.8981
442 3XX 0.8978
443 ES7 0.8977
444 R1X 0.8976
445 03V 0.8975
446 7HP 0.8973
447 K2T 0.8973
448 PAE 0.8971
449 JB5 0.8969
450 HUI 0.8968
451 IFM 0.8966
452 9HX 0.8966
453 PRI 0.8966
454 JKE 0.8965
455 1AC 0.8965
456 03W 0.8962
457 AZF 0.8962
458 3OH 0.8962
459 FBB 0.8960
460 2AQ 0.8959
461 ISN 0.8958
462 XRG 0.8958
463 VNJ 0.8958
464 3ZS 0.8954
465 PYR 0.8954
466 PRS 0.8954
467 6M9 0.8952
468 4FS 0.8951
469 HDA 0.8951
470 2RA 0.8950
471 AAE 0.8950
472 BAL 0.8949
473 7W4 0.8949
474 IT2 0.8948
475 DBB 0.8947
476 A3B 0.8947
477 COU 0.8945
478 192 0.8942
479 DYA 0.8942
480 HYP 0.8941
481 DPR 0.8940
482 HSM 0.8939
483 NOJ 0.8939
484 KKN 0.8938
485 94N 0.8937
486 ES5 0.8936
487 RUU 0.8934
488 DAB 0.8933
489 BNS 0.8932
490 4FA 0.8930
491 C2A 0.8927
492 RP7 0.8927
493 ABU 0.8925
494 AKB 0.8923
495 PEA 0.8920
496 7WV 0.8916
497 1DW 0.8913
498 DCY 0.8911
499 HH5 0.8911
500 ILE 0.8909
501 OXM 0.8909
502 SRT 0.8908
503 0PY 0.8907
504 PHZ 0.8907
505 9YL 0.8906
506 1P8 0.8904
507 OXZ 0.8904
508 BZ3 0.8903
509 XQ0 0.8902
510 KPL 0.8902
511 BSX 0.8901
512 5OB 0.8901
513 OXL 0.8901
514 YTB 0.8901
515 ES2 0.8900
516 FUF 0.8899
517 BNZ 0.8899
518 YRL 0.8898
519 6M4 0.8897
520 B20 0.8896
521 2DR 0.8896
522 H42 0.8895
523 LEA 0.8894
524 KYD 0.8893
525 2A9 0.8892
526 DX4 0.8892
527 RM4 0.8892
528 OK7 0.8890
529 ITN 0.8889
530 CXF 0.8886
531 47J 0.8884
532 OCH 0.8881
533 FP1 0.8881
534 AGK 0.8880
535 HIO 0.8880
536 P1R 0.8879
537 3V4 0.8878
538 IP0 0.8878
539 E5X 0.8878
540 ARA 0.8877
541 6GU 0.8877
542 XBT 0.8876
543 DTL 0.8874
544 AZA 0.8870
545 CFP 0.8870
546 RNS 0.8867
547 9DG 0.8863
548 M2H 0.8863
549 6F0 0.8862
550 IFL 0.8857
551 GUN 0.8856
552 8GC 0.8853
553 AEF 0.8852
554 CRN 0.8850
555 XAN 0.8849
556 Q88 0.8848
557 SAR 0.8848
558 BUA 0.8847
559 BAE 0.8846
560 ADZ 0.8846
561 0CU 0.8845
562 1DQ 0.8845
563 6AP 0.8844
564 SEJ 0.8844
565 GLL 0.8843
566 6SP 0.8843
567 PYM 0.8843
568 IPB 0.8843
569 LAC 0.8842
570 A2F 0.8840
571 ASN 0.8840
572 FCB 0.8839
573 ES0 0.8839
574 FUB 0.8838
575 JBK 0.8837
576 ITU 0.8835
577 261 0.8834
578 NMG 0.8834
579 L3Q 0.8832
580 DGJ 0.8831
581 ASP 0.8831
582 YH7 0.8830
583 HGY 0.8826
584 DBH 0.8826
585 7B4 0.8825
586 2ZV 0.8825
587 MNM 0.8825
588 7N0 0.8825
589 C2N 0.8824
590 290 0.8822
591 1XM 0.8821
592 G2F 0.8821
593 1M2 0.8820
594 PEL 0.8819
595 3HA 0.8818
596 ZBT 0.8818
597 G4D 0.8817
598 3F0 0.8817
599 3ID 0.8815
600 CP 0.8815
601 82I 0.8813
602 CWM 0.8811
603 OXD 0.8810
604 BCP 0.8807
605 4BZ 0.8807
606 IHG 0.8806
607 RBJ 0.8806
608 XXR 0.8806
609 WDL 0.8804
610 BUO 0.8804
611 NMJ 0.8803
612 RHU 0.8800
613 XIY 0.8798
614 AX2 0.8798
615 IQ0 0.8796
616 5Y9 0.8796
617 IGA 0.8795
618 GAL 0.8794
619 Z6J 0.8794
620 4CS 0.8794
621 3M0 0.8793
622 2D0 0.8792
623 CHT 0.8790
624 DMD 0.8789
625 ISZ 0.8788
626 141 0.8787
627 CEE 0.8787
628 P9P 0.8785
629 HCS 0.8784
630 NOY 0.8783
631 DHB 0.8780
632 ANN 0.8777
633 4XH 0.8777
634 HH8 0.8776
635 3HB 0.8773
636 GRE 0.8773
637 XX2 0.8773
638 4NC 0.8773
639 PAF 0.8772
640 6UA 0.8771
641 GIF 0.8771
642 QWN 0.8771
643 QXW 0.8769
644 M6W 0.8769
645 MYJ 0.8768
646 BPN 0.8767
647 O72 0.8765
648 PBE 0.8763
649 51F 0.8762
650 NVA 0.8761
651 PGA 0.8760
652 1SQ 0.8759
653 AZG 0.8758
654 3NT 0.8757
655 MR1 0.8756
656 5Q0 0.8755
657 PNZ 0.8753
658 F9Y 0.8751
659 MFB 0.8751
660 SAN 0.8751
661 S0H 0.8750
662 IHB 0.8750
663 JZ7 0.8749
664 GLU 0.8749
665 5HN 0.8748
666 2ZX 0.8747
667 FHB 0.8746
668 1LQ 0.8744
669 6M1 0.8744
670 3RK 0.8740
671 5AN 0.8740
672 3AB 0.8740
673 5SG 0.8740
674 40E 0.8740
675 4A3 0.8739
676 GAB 0.8739
677 SN4 0.8738
678 9TW 0.8737
679 JA8 0.8736
680 JLZ 0.8736
681 2HO 0.8735
682 FW5 0.8735
683 SGL 0.8735
684 HQY 0.8734
685 13X 0.8733
686 TEO 0.8733
687 CHB 0.8732
688 4ZC 0.8732
689 ASO 0.8730
690 1NP 0.8730
691 NXA 0.8729
692 BOA 0.8728
693 LCN 0.8724
694 4NM 0.8724
695 260 0.8724
696 24W 0.8724
697 B57 0.8723
698 JPZ 0.8721
699 4YS 0.8721
700 4P5 0.8720
701 5IQ 0.8720
702 MRZ 0.8720
703 PAV 0.8720
704 DHR 0.8719
705 IF7 0.8719
706 QSB 0.8717
707 93K 0.8717
708 7HQ 0.8717
709 1LM 0.8715
710 JBH 0.8714
711 ES1 0.8714
712 NCM 0.8713
713 OVV 0.8712
714 3AY 0.8711
715 1DV 0.8711
716 PKU 0.8710
717 GOO 0.8709
718 I3A 0.8709
719 2BG 0.8708
720 3HM 0.8700
721 259 0.8698
722 271 0.8697
723 3Z7 0.8696
724 NNO 0.8696
725 BUB 0.8694
726 THE 0.8693
727 BHO 0.8693
728 HV2 0.8690
729 3HR 0.8688
730 PTO 0.8687
731 INO 0.8687
732 53C 0.8685
733 3DO 0.8684
734 TAR 0.8682
735 6HQ 0.8682
736 GLA 0.8682
737 COI 0.8680
738 WCE 0.8675
739 HY1 0.8674
740 BR8 0.8674
741 EGD 0.8674
742 NIZ 0.8670
743 BRT 0.8670
744 F5B 0.8668
745 EQT 0.8664
746 PEP 0.8664
747 1P7 0.8663
748 N5J 0.8663
749 PZI 0.8661
750 3BZ 0.8660
751 TSU 0.8659
752 5ZE 0.8657
753 TIU 0.8655
754 FB2 0.8654
755 TB6 0.8654
756 HHA 0.8648
757 XUL 0.8645
758 RB5 0.8644
759 H76 0.8633
760 JZ4 0.8632
761 2LP 0.8632
762 KJH 0.8632
763 5B1 0.8630
764 3HL 0.8623
765 MAN 0.8623
766 LZM 0.8619
767 ALA 0.8611
768 12Q 0.8611
769 RAM 0.8610
770 IVA 0.8609
771 5RG 0.8609
772 3GR 0.8608
773 TNE 0.8607
774 TZE 0.8607
775 4JT 0.8600
776 4WL 0.8598
777 98J 0.8593
778 CFI 0.8592
779 2OP 0.8590
780 BTY 0.8589
781 2HE 0.8585
782 LRH 0.8580
783 3SL 0.8577
784 KJY 0.8575
785 V55 0.8571
786 DAL 0.8570
787 4M4 0.8570
788 PHU 0.8567
789 86J 0.8565
790 42A 0.8564
791 AAS 0.8560
792 FBS 0.8557
793 AC5 0.8554
794 4J8 0.8549
795 5QX 0.8545
796 4AA 0.8545
797 O7U 0.8543
798 SNE 0.8543
799 GTQ 0.8543
800 EXO 0.8539
801 FBM 0.8533
802 PMB 0.8527
803 PRY 0.8510
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6QXD; Ligand: JKB; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 6qxd.bio1) has 20 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback