Receptor
PDB id Resolution Class Description Source Keywords
5IFS 2.46 Å NON-ENZYME: OTHER QUANTITATIVE INTERACTION MAPPING REVEALS AN EXTENDED UBIQUIT REGULATORY DOMAIN IN ASPL THAT DISRUPTS FUNCTIONAL P97 HEXAI NDUCES CELL DEATH HOMO SAPIENS ASPL P97 DISASSEMBLY EUBX SIGNALING PROTEIN
Ref.: QUANTITATIVE INTERACTION MAPPING REVEALS AN EXTENDE DOMAIN IN ASPL THAT DISRUPTS FUNCTIONAL P97 HEXAMER NAT COMMUN V. 7 13047 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
EDO D:503;
B:504;
B:505;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
MG B:502;
D:502;
Invalid;
Invalid;
none;
none;
submit data
24.305 Mg [Mg+2...
ADP B:501;
D:501;
Valid;
Valid;
none;
none;
submit data
427.201 C10 H15 N5 O10 P2 c1nc(...
GOL B:506;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
SO4 B:503;
Invalid;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5IFS 2.46 Å NON-ENZYME: OTHER QUANTITATIVE INTERACTION MAPPING REVEALS AN EXTENDED UBIQUIT REGULATORY DOMAIN IN ASPL THAT DISRUPTS FUNCTIONAL P97 HEXAI NDUCES CELL DEATH HOMO SAPIENS ASPL P97 DISASSEMBLY EUBX SIGNALING PROTEIN
Ref.: QUANTITATIVE INTERACTION MAPPING REVEALS AN EXTENDE DOMAIN IN ASPL THAT DISRUPTS FUNCTIONAL P97 HEXAMER NAT COMMUN V. 7 13047 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 5IFS - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 5IFS - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 5IFS - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADP; Similar ligands found: 435
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 ATP 0.9 1
3 A2D 0.895522 0.971831
4 AQP 0.887324 1
5 5FA 0.887324 1
6 AP5 0.884058 0.971831
7 B4P 0.884058 0.971831
8 BA3 0.869565 0.971831
9 AN2 0.84507 0.985915
10 M33 0.833333 0.958333
11 ACQ 0.826667 0.972222
12 A 0.823529 0.971429
13 AMP 0.823529 0.971429
14 ACP 0.821918 0.972222
15 AR6 0.810811 0.971831
16 APR 0.810811 0.971831
17 ANP 0.802632 0.972222
18 AD9 0.8 0.972222
19 AGS 0.8 0.945946
20 SAP 0.8 0.945946
21 ADX 0.783784 0.873418
22 CA0 0.783784 0.945205
23 TAT 0.779221 0.958904
24 AMP MG 0.774648 0.891892
25 50T 0.773333 0.958333
26 ABM 0.763889 0.917808
27 APC 0.763158 0.958904
28 PRX 0.763158 0.893333
29 ATF 0.759494 0.958904
30 A22 0.753086 0.985915
31 A12 0.743243 0.958904
32 AP2 0.743243 0.958904
33 ADP MG 0.736842 0.905405
34 SRA 0.736111 0.918919
35 ADQ 0.73494 0.945205
36 25L 0.732558 0.985915
37 ADP BEF 0.727273 0.881579
38 BEF ADP 0.727273 0.881579
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 ADP PO3 0.708861 0.943662
44 PAP 0.708861 0.985714
45 ATR 0.708861 0.971429
46 SRP 0.707317 0.906667
47 7D3 0.706667 0.905405
48 25A 0.702381 0.971831
49 ATP MG 0.7 0.905405
50 OAD 0.697674 0.945205
51 RBY 0.6875 0.932432
52 ADV 0.6875 0.932432
53 00A 0.686047 0.883117
54 5SV 0.682353 0.848101
55 8QN 0.682353 0.931507
56 OOB 0.682353 0.931507
57 3OD 0.681818 0.945205
58 BIS 0.681818 0.933333
59 ADP ALF 0.674699 0.87013
60 ALF ADP 0.674699 0.87013
61 AMO 0.674419 0.932432
62 4AD 0.674419 0.92
63 PAJ 0.674419 0.884615
64 GAP 0.670732 0.893333
65 MAP 0.670588 0.945946
66 DLL 0.666667 0.931507
67 ANP MG 0.666667 0.894737
68 VO4 ADP 0.666667 0.931507
69 AHX 0.666667 0.896104
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LAD 0.651685 0.860759
75 WAQ 0.651685 0.883117
76 PR8 0.651685 0.85
77 ITT 0.65 0.943662
78 7D4 0.65 0.905405
79 G5P 0.648936 0.921053
80 RAB 0.647059 0.84507
81 ADN 0.647059 0.84507
82 XYA 0.647059 0.84507
83 TXA 0.644444 0.932432
84 1ZZ 0.644444 0.839506
85 ME8 0.644444 0.839506
86 NB8 0.644444 0.896104
87 FYA 0.644444 0.905405
88 6AD 0.642857 0.909091
89 ADP BMA 0.640449 0.918919
90 G3A 0.638298 0.921053
91 DAL AMP 0.632184 0.905405
92 AFH 0.631579 0.884615
93 9SN 0.630435 0.871795
94 GTA 0.625 0.886076
95 YAP 0.623656 0.894737
96 FA5 0.623656 0.906667
97 UP5 0.622449 0.92
98 XAH 0.617021 0.839506
99 AV2 0.616279 0.917808
100 AOC 0.615385 0.821918
101 48N 0.612245 0.896104
102 4UV 0.610526 0.894737
103 TXD 0.606061 0.907895
104 DND 0.606061 0.932432
105 NAX 0.606061 0.873418
106 NXX 0.606061 0.932432
107 NAI 0.606061 0.907895
108 6V0 0.606061 0.896104
109 5N5 0.605634 0.819444
110 5AS 0.604938 0.77907
111 A4P 0.60396 0.843373
112 DAT 0.60241 0.905405
113 A2R 0.602273 0.985915
114 TXE 0.6 0.907895
115 OMR 0.6 0.851852
116 4UU 0.597938 0.894737
117 A A 0.597826 0.944444
118 A4D 0.597222 0.819444
119 5CD 0.597222 0.805556
120 AP0 0.594059 0.896104
121 4TC 0.594059 0.896104
122 A3P 0.592593 0.971429
123 139 0.592233 0.873418
124 T5A 0.592233 0.841463
125 7D5 0.592105 0.878378
126 ATP A A A 0.589474 0.930556
127 LAQ 0.585859 0.839506
128 MYR AMP 0.585106 0.817073
129 YLP 0.58 0.819277
130 UPA 0.578431 0.907895
131 7DD 0.578313 0.985714
132 ADJ 0.576923 0.851852
133 3AM 0.576923 0.929577
134 COD 0.575472 0.811765
135 NAD 0.575472 0.931507
136 3AT 0.574713 0.971831
137 JB6 0.574468 0.883117
138 4UW 0.574257 0.860759
139 EP4 0.573333 0.753247
140 A2P 0.573171 0.957143
141 CNA 0.571429 0.932432
142 TYM 0.568627 0.906667
143 PPS 0.568182 0.873418
144 TYR AMP 0.56701 0.881579
145 DTA 0.565789 0.786667
146 M2T 0.565789 0.734177
147 AR6 AR6 0.565657 0.917808
148 A3D 0.564815 0.918919
149 3DH 0.564103 0.773333
150 G5A 0.563218 0.77907
151 YLB 0.563107 0.819277
152 YLC 0.563107 0.839506
153 AMP DBH 0.561224 0.893333
154 MTA 0.558442 0.773333
155 DTP 0.556818 0.905405
156 AHZ 0.554455 0.817073
157 NA7 0.553191 0.958904
158 IOT 0.552381 0.831325
159 7MD 0.55 0.8625
160 ZAS 0.55 0.766234
161 IMO 0.548781 0.929577
162 YLA 0.54717 0.819277
163 NAE 0.544643 0.894737
164 TAD 0.544554 0.884615
165 A5A 0.544444 0.807229
166 2AM 0.544304 0.943662
167 TSB 0.543478 0.819277
168 6RE 0.54321 0.759494
169 AYB 0.542056 0.809524
170 NAQ 0.539823 0.871795
171 V3L 0.539326 0.971831
172 ARG AMP 0.539216 0.829268
173 AF3 ADP 3PG 0.538462 0.8375
174 SSA 0.538462 0.8
175 LA8 ALF 3PG 0.538462 0.8375
176 ALF ADP 3PG 0.538462 0.8375
177 ZID 0.535088 0.918919
178 LPA AMP 0.533981 0.817073
179 54H 0.532609 0.788235
180 52H 0.532609 0.77907
181 VMS 0.532609 0.788235
182 BTX 0.53211 0.841463
183 J7C 0.53012 0.769231
184 A3N 0.53012 0.786667
185 5X8 0.528736 0.763158
186 BT5 0.527273 0.831325
187 5CA 0.526882 0.8
188 53H 0.526882 0.77907
189 ARU 0.526316 0.860759
190 EAD 0.525862 0.873418
191 RGT 0.525253 0.958904
192 OVE 0.52439 0.905405
193 S4M 0.52381 0.666667
194 7DT 0.522727 0.985714
195 GDP 0.522222 0.92
196 DDS 0.522222 0.878378
197 AVV 0.521277 0.896104
198 NDE 0.521008 0.932432
199 7MC 0.518868 0.841463
200 DSH 0.518072 0.725
201 MAO 0.517647 0.759036
202 LSS 0.515789 0.761364
203 DSZ 0.515789 0.8
204 NSS 0.515789 0.8
205 P5A 0.515464 0.744444
206 DZD 0.513514 0.884615
207 NVA LMS 0.510417 0.761364
208 12D 0.509615 0.785714
209 NAD IBO 0.509091 0.87013
210 M24 0.508772 0.85
211 YLY 0.508772 0.809524
212 P1H 0.508333 0.851852
213 5AD 0.506849 0.746479
214 GJV 0.505882 0.75
215 LEU LMS 0.505155 0.761364
216 G A A A 0.504505 0.871795
217 4TA 0.504505 0.807229
218 NAJ PZO 0.504425 0.848101
219 KAA 0.5 0.752809
220 NDC 0.5 0.871795
221 7D7 0.5 0.743243
222 71V 0.5 0.907895
223 A3G 0.5 0.8
224 128 0.5 0.776471
225 GSU 0.5 0.77907
226 N0B 0.495726 0.819277
227 NJP 0.495495 0.945946
228 ODP 0.495495 0.909091
229 2SA 0.494624 0.932432
230 6C6 0.494505 0.881579
231 SFG 0.494382 0.75
232 0WD 0.491071 0.921053
233 YSA 0.490196 0.77907
234 PO4 PO4 A A A A PO4 0.489796 0.902778
235 6IA 0.48913 0.8375
236 SAM 0.48913 0.690476
237 A7D 0.488636 0.776316
238 6FA 0.488 0.841463
239 FB0 0.487805 0.804598
240 NAJ PYZ 0.487179 0.85
241 IDP 0.483516 0.918919
242 A5D 0.483516 0.786667
243 SA8 0.483516 0.707317
244 MHZ 0.483146 0.697674
245 PGS 0.483146 0.883117
246 D5M 0.482353 0.878378
247 DA 0.482353 0.878378
248 NEC 0.482353 0.746667
249 NIA 0.481928 0.822785
250 Y3J 0.480519 0.726027
251 FAD 0.480315 0.851852
252 FAS 0.480315 0.851852
253 FDA 0.48 0.833333
254 N6P 0.479592 0.915493
255 GGZ 0.479167 0.825
256 SAH 0.478261 0.74359
257 SAI 0.478261 0.734177
258 NPW 0.477477 0.886076
259 NDP 0.477477 0.921053
260 AAM 0.476744 0.971429
261 AMZ 0.47561 0.916667
262 C2R 0.47561 0.90411
263 A A A 0.474747 0.905405
264 GTP 0.473684 0.92
265 U A G G 0.473684 0.883117
266 SMM 0.473684 0.686047
267 TXP 0.473214 0.921053
268 NZQ 0.473214 0.909091
269 A3S 0.47191 0.810811
270 AMP NAD 0.470588 0.881579
271 SFD 0.46875 0.734043
272 AIR 0.468354 0.901408
273 AAT 0.468085 0.707317
274 EEM 0.468085 0.690476
275 Z5A 0.466667 0.77907
276 7C5 0.466667 0.818182
277 J7V 0.466667 0.833333
278 62F 0.465649 0.8625
279 FAY 0.462121 0.8625
280 ETB 0.461538 0.833333
281 DCA 0.461538 0.823529
282 A3T 0.461538 0.821918
283 A6D 0.46 0.722892
284 A U 0.459459 0.87013
285 6K6 0.459184 0.930556
286 GEK 0.459184 0.7375
287 RFL 0.458647 0.821429
288 S7M 0.458333 0.690476
289 NAP 0.458333 0.945205
290 4YB 0.457944 0.761364
291 WSA 0.454545 0.788235
292 TAP 0.454545 0.907895
293 FNK 0.454545 0.804598
294 COA 0.453782 0.823529
295 0T1 0.453782 0.823529
296 101 0.453488 0.878378
297 XNP 0.452174 0.873418
298 NA0 0.45082 0.932432
299 7RP 0.448276 0.928571
300 GP3 0.446809 0.921053
301 TM1 0.446602 0.77381
302 APU 0.446429 0.894737
303 PUA 0.445378 0.884615
304 V1N 0.443396 0.917808
305 7RA 0.443182 0.957747
306 30N 0.442623 0.752688
307 CAO 0.442623 0.795455
308 AMX 0.442623 0.833333
309 COS 0.442623 0.804598
310 ACK 0.44186 0.861111
311 QQY 0.44186 0.815789
312 649 0.441441 0.744444
313 0UM 0.44 0.698795
314 NHD 0.439655 0.905405
315 CMX 0.439024 0.823529
316 SCO 0.439024 0.823529
317 GCP 0.438776 0.896104
318 8BR 0.438202 0.906667
319 GNH 0.4375 0.907895
320 3AD 0.4375 0.805556
321 62X 0.435644 0.666667
322 ACO 0.435484 0.795455
323 FCX 0.435484 0.795455
324 FAM 0.435484 0.804598
325 GNP 0.434343 0.896104
326 NMX 0.433071 0.76087
327 MGP 0.43299 0.884615
328 PLP AAD 0.432203 0.741573
329 26A 0.432099 0.763158
330 HAX 0.432 0.804598
331 K15 0.431373 0.682353
332 DG1 0.430894 0.921053
333 1DG 0.430894 0.921053
334 QQX 0.430233 0.805195
335 2VA 0.430108 0.8
336 S8M 0.43 0.759494
337 2MC 0.429688 0.769231
338 3KK 0.428571 0.804598
339 6G0 0.428571 0.884615
340 FYN 0.428571 0.823529
341 P5F 0.428571 0.823529
342 NAD BBN 0.428571 0.841463
343 U G A 0.427481 0.839506
344 AS 0.426966 0.833333
345 FAI 0.426966 0.916667
346 RMB 0.426966 0.873239
347 1RB 0.425287 0.885714
348 MCD 0.425197 0.804598
349 OXK 0.425197 0.804598
350 COK 0.425197 0.804598
351 CA6 0.425197 0.729167
352 SOP 0.425197 0.804598
353 G1R 0.424242 0.907895
354 CC5 0.423077 0.816901
355 SXZ 0.423077 0.710843
356 F2N 0.422535 0.813953
357 NAD CJ3 0.422222 0.811765
358 ANZ 0.422018 0.8
359 CMC 0.421875 0.804598
360 CO6 0.421875 0.804598
361 1VU 0.421875 0.795455
362 ZDA 0.421053 0.864865
363 GDD 0.420561 0.884615
364 GKE 0.420561 0.884615
365 GDC 0.420561 0.884615
366 NFD 0.420168 0.883117
367 GSP 0.42 0.873418
368 D3Y 0.42 0.789474
369 MC4 0.419847 0.76087
370 3L1 0.419753 0.773333
371 3D1 0.419753 0.773333
372 FA9 0.41958 0.864198
373 5GP 0.419355 0.906667
374 G 0.419355 0.906667
375 KB1 0.419048 0.698795
376 SCD 0.418605 0.823529
377 CAJ 0.418605 0.804598
378 2BA 0.417582 0.915493
379 CMP 0.417582 0.901408
380 SO8 0.416667 0.789474
381 N01 0.416667 0.905405
382 VRT 0.416667 0.769231
383 3HC 0.415385 0.813953
384 A1S 0.415385 0.804598
385 BCO 0.415385 0.804598
386 IVC 0.415385 0.813953
387 MLC 0.415385 0.804598
388 1HE 0.415385 0.786517
389 NMN AMP PO4 0.415254 0.87013
390 2FA 0.414634 0.813333
391 MGO 0.414141 0.860759
392 3NZ 0.413462 0.782051
393 MCA 0.412214 0.795455
394 CAA 0.412214 0.813953
395 YE1 0.412214 0.813953
396 COO 0.412214 0.804598
397 GAV 0.411765 0.884615
398 P2P 0.411111 0.902778
399 JLN 0.411111 0.890411
400 ZZB 0.410256 0.77381
401 CNV FAD 0.410072 0.793103
402 SCA 0.409091 0.804598
403 RP1 0.409091 0.842105
404 103 0.409091 0.837838
405 2CP 0.409091 0.795455
406 SP1 0.409091 0.842105
407 PAX 0.408 0.829268
408 FAD NBT 0.407143 0.75
409 NVA 2AD 0.40625 0.74359
410 COW 0.406015 0.795455
411 BYC 0.406015 0.804598
412 2KQ 0.406015 0.786517
413 COF 0.406015 0.786517
414 3CP 0.406015 0.804598
415 IRC 0.406015 0.813953
416 1GZ 0.406015 0.795455
417 HGG 0.406015 0.804598
418 CA8 0.406015 0.729167
419 G2P 0.405941 0.884615
420 SLU 0.404959 0.770115
421 U A C C 0.404959 0.858974
422 RBZ 0.404494 0.849315
423 1CZ 0.404412 0.795455
424 BCA 0.402985 0.795455
425 FAQ 0.402985 0.804598
426 4CA 0.402985 0.795455
427 MTP 0.402439 0.730769
428 8OD 0.402062 0.945205
429 CO7 0.401515 0.804598
430 DAL FAD PER 0.401408 0.809524
431 G2R 0.4 0.884615
432 HXC 0.4 0.786517
433 ENQ 0.4 0.916667
434 GMV 0.4 0.896104
435 GRA 0.4 0.804598
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5IFS; Ligand: ADP; Similar sites found: 372
This union binding pocket(no: 1) in the query (biounit: 5ifs.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1BG2 ADP 0.000001344 0.47345 2.15385
2 1V8K ANP 0.00004075 0.51894 2.53165
3 1JWY ADP 0.0001342 0.48816 2.53165
4 4ZNL BEF ADP 0.0001386 0.48752 2.53165
5 1YRB GDP 0.00005767 0.48679 2.53165
6 1JWY GDP 0.0002459 0.46069 2.53165
7 4KBF AMP 0.001104 0.45673 2.53165
8 4ZG4 VO4 ADP 0.000218 0.42003 2.53165
9 1SQ5 ADP 0.00004532 0.5099 2.5974
10 4IEE AGS 0.0002255 0.49022 2.95359
11 2ZJ5 ADP 0.01785 0.40507 2.95359
12 2J5V PCA 0.03924 0.4013 2.95359
13 3ZL8 ADP 0.01116 0.40351 2.97483
14 4NON GDP 0.00008831 0.50306 3.07692
15 5TSH ADP 0.00000767 0.57537 3.1185
16 5TSH ANP 0.000003428 0.56977 3.1185
17 1YZN GNP 0.0001243 0.40793 3.24324
18 1T5C ADP 0.000001267 0.6327 3.37553
19 2IS6 ADP 0.000005087 0.56167 3.37553
20 2GK6 ADP 0.00004166 0.53367 3.37553
21 1Z6T ADP 0.00001232 0.50531 3.37553
22 3EC1 GDP 0.00091 0.44982 3.37553
23 4YS0 ADP 0.0005286 0.43883 3.37553
24 2FAH GDP 0.001016 0.43432 3.37553
25 4IDN GNP 0.0004301 0.41667 3.37553
26 3LGS ADE 0.02063 0.40043 3.37553
27 1F6B GDP 0.00008843 0.49652 3.53535
28 4AG5 ADP 0.00001151 0.56837 3.57143
29 1Y3A GDP 0.00005093 0.44429 3.64742
30 2OM2 GDP 0.0001633 0.44162 3.69231
31 3FYH ADP 0.0002289 0.4082 3.72671
32 1GOJ ADP 0.0000009452 0.6378 3.79747
33 1SKQ GDP 0.00006808 0.51547 3.79747
34 2VF7 ADP 0.00008598 0.49708 3.79747
35 1BH2 GSP 0.00008878 0.40474 3.80952
36 1D8T GDP 0.00008856 0.503 3.81679
37 3DEF GDP 0.0001412 0.47014 3.81679
38 2BVN GNP 0.0003015 0.45633 3.81679
39 2QLU ADE 0.01628 0.40124 3.82166
40 1Z0F GDP 0.00001929 0.52702 3.91061
41 1UKZ ADP 0.0003339 0.49333 3.94089
42 4R98 GNH 0.000187 0.48765 4.05904
43 3DKP ADP 0.0001391 0.49373 4.08163
44 5X40 ACP 0.0004209 0.47344 4.10959
45 3REF GDP 0.0003042 0.42079 4.12371
46 4LJ9 ACP 0.00004824 0.51547 4.12979
47 3BP1 GUN 0.006532 0.42262 4.13793
48 4ARE FLC 0.01104 0.41087 4.158
49 5GJC ATP 0.00004639 0.51628 4.21941
50 2WIC GNP 0.00003678 0.51408 4.21941
51 3P4X ADP 0.00001766 0.49131 4.21941
52 5LB3 ADP 0.0003055 0.48383 4.21941
53 2Q2Y MKR 0.0008827 0.47923 4.21941
54 2Q2Y ADP 0.0009323 0.47923 4.21941
55 3NHB ADP 0.000005986 0.58318 4.24837
56 1G6H ADP 0.0000002747 0.66674 4.28016
57 1D2E GDP 0.0002126 0.4626 4.28212
58 5EP2 AZU 0.00006182 0.46496 4.29688
59 4WOP CTP 0.0009067 0.41211 4.44444
60 3FWY ADP 0.0002733 0.44896 4.4586
61 5KSZ GCP 0.000422 0.45983 4.48113
62 4FCW ADP 0.000007824 0.52951 4.50161
63 1OXV ANP 0.00002868 0.53369 4.53258
64 2GDJ ANP 0.0001219 0.49643 4.54545
65 1ZC3 GNP 0.0001695 0.40341 4.57143
66 4DCT GDP 0.00006477 0.50275 4.60526
67 1MKY GDP 0.00003492 0.52211 4.64135
68 4PFO ADP 0.0003426 0.48142 4.64135
69 2JLR ANP 0.0002287 0.46117 4.64135
70 1IHU AF3 0.0002038 0.42947 4.64135
71 2C77 GNP 0.0003763 0.4265 4.64135
72 1IHU ADP 0.0002258 0.42077 4.64135
73 2C78 GNP 0.0004218 0.41744 4.64135
74 4D42 W0I 0.02673 0.41599 4.64135
75 4D42 NAP 0.02673 0.41599 4.64135
76 1A4R GNH 0.0002457 0.44936 4.71204
77 1A4R GDP 0.0001812 0.44587 4.71204
78 1YVD GNP 0.0001667 0.40984 4.73373
79 1U8Z GDP 0.0001588 0.42486 4.7619
80 1Z06 GNP 0.0001662 0.41676 4.7619
81 4WZ6 ATP 0.00001449 0.56387 4.82759
82 2HF9 GSP 0.00003211 0.43644 4.86726
83 3DC4 ADP 0.00001232 0.56005 4.94186
84 2VVG ADP 0.000001113 0.63334 5.06329
85 4PX9 ADP 0.00008992 0.50961 5.06329
86 3QKT ANP 0.0002774 0.41237 5.06329
87 1OYY AGS 0.007815 0.41091 5.06329
88 2ZPA ADP 0.000008838 0.49993 5.1975
89 4ITR GDP 0.0003144 0.43813 5.2356
90 4QM7 GTP 0.00008705 0.50335 5.26316
91 5KUT GDP 0.00004297 0.49543 5.29101
92 1PUJ GNP 0.0001413 0.47039 5.31915
93 1I4D GDP 0.00008435 0.51096 5.35714
94 2ZEJ GDP 0.0001394 0.40707 5.43478
95 3BFV ADP 0.00005462 0.51292 5.48523
96 4PJ3 ANP 0.000128 0.47444 5.48523
97 1NST A3P 0.003773 0.40405 5.53846
98 3T1O GDP 0.00006803 0.49551 5.55556
99 1H65 GDP 0.0002 0.42925 5.55556
100 1NJF ADP 0.000002328 0.57074 5.6
101 1NJF AGS 0.000004951 0.561 5.6
102 3RC3 ANP 0.003032 0.43542 5.61331
103 3QBT GNP 0.00008787 0.41915 5.71429
104 2HT6 GDP 0.000008042 0.5605 5.74713
105 1JJ7 ADP 0.0000003093 0.66549 5.76923
106 5KSP GDP 0.0002371 0.47677 5.78947
107 1TQ4 GDP 0.00006413 0.45532 5.81114
108 2D7D ADP 0.0002019 0.48607 5.82121
109 3WXM GTP 0.0006936 0.46699 5.85106
110 5CK5 GDP 0.000003714 0.57678 5.90717
111 1FP6 ADP 0.0003475 0.45358 5.90717
112 4NCN GTP 0.000243 0.41757 5.9081
113 4DID GDP 0.0002271 0.47763 5.92105
114 1L2T ATP 0.0003204 0.40452 5.95745
115 5GVR LMR 0.0001097 0.51022 5.98291
116 2KIN ADP 0.00000147 0.47215 6
117 5HR5 ADP 0.00009897 0.4662 6.02911
118 2F9L GDP 0.0001752 0.42306 6.03015
119 4XTR ADP 0.0001256 0.45653 6.08696
120 4XTR ATP 0.0001748 0.4291 6.08696
121 4XVU ATP 0.0001819 0.42854 6.08696
122 4U00 ADP 0.0000008131 0.6364 6.14754
123 1OIV GDP 0.0003158 0.48309 6.28272
124 1OIX GDP 0.0002626 0.40499 6.28272
125 2ZE7 AMP 0.006524 0.42105 6.32411
126 2ZE7 DST 0.007023 0.42105 6.32411
127 3A4M ADP 0.00001471 0.55622 6.32911
128 2OG2 MLI 0.00004442 0.5393 6.32911
129 3B9Q MLI 0.0001512 0.51148 6.32911
130 1ION ADP 0.00009448 0.48908 6.32911
131 2XAU ADP 0.0007598 0.44833 6.32911
132 4RD0 GDP 0.0002758 0.42368 6.32911
133 3GJ0 GDP 0.00002206 0.53154 6.33484
134 3GJ4 GDP 0.00002666 0.52765 6.33484
135 3GJ5 GDP 0.00003709 0.51392 6.33484
136 2NGR GDP 0.00009603 0.49487 6.41026
137 1NRJ GTP 0.00007343 0.4539 6.42202
138 1IBR GNP 0.0002162 0.40011 6.48148
139 2FH5 GTP 0.00006316 0.45607 6.48649
140 2XTZ GSP 0.0002928 0.40302 6.49718
141 3UIE ANP 0.0001817 0.4763 6.5
142 1KSH GDP 0.0002756 0.47783 6.57895
143 3A1S GDP 0.0001594 0.48471 6.58915
144 5L3V GDP 0.00009279 0.48944 6.68896
145 1YQT ADP 0.000004605 0.58852 6.75105
146 5M04 GDP 0.00001838 0.54307 6.75105
147 2ZFI ADP 0.00004549 0.51668 6.75105
148 3VX3 ADP 0.000117 0.45818 6.75105
149 2C04 GCP 0.001602 0.41948 6.75105
150 2WKQ GTP 0.0003177 0.41228 6.75105
151 1KO8 6PG 0.0001009 0.45887 6.85714
152 5I0H ADP BEF 0.0002322 0.43353 6.86071
153 1ZD9 GDP 0.00007835 0.46108 6.91489
154 1OE0 TTP 0.004857 0.42866 6.95652
155 1Z0K GTP 0.00006389 0.43817 6.97674
156 2DPY ADP 0.0001212 0.51054 7.07763
157 3Q85 GNP 0.00002565 0.52844 7.10059
158 1DAR GDP 0.0001412 0.49342 7.173
159 3COB ADP 0.000001448 0.48926 7.173
160 4FRZ ADP 0.000004884 0.48674 7.173
161 2FSH ANP 0.0007758 0.46418 7.173
162 3BER AMP 0.002805 0.43201 7.173
163 1KAO GDP 0.0001238 0.4624 7.18563
164 3Q72 GNP 0.00001152 0.49959 7.22892
165 2DWU DGL 0.01113 0.40792 7.24638
166 4MKF AP5 0.0003185 0.50352 7.37327
167 1GRN GDP 0.0002075 0.45246 7.38916
168 1D5C GDP 0.00009278 0.46705 7.40741
169 3AB3 GDP 0.0001562 0.48921 7.45856
170 5MZN ADP 0.00009664 0.51545 7.48441
171 1U0J ADP 0.00004653 0.5235 7.49064
172 4TMK T5A 0.01934 0.40763 7.51174
173 1W5T ANP 0.0000009117 0.5309 7.52427
174 1W5T ADP 0.000005171 0.52366 7.52427
175 3RWO GDP 0.0002431 0.40596 7.56757
176 4LC1 GDP 0.00003776 0.5205 7.59494
177 4P32 ADP 0.0003687 0.41712 7.63052
178 1SVI GDP 0.00006156 0.51759 7.69231
179 3PQC GDP 0.0004158 0.46012 7.69231
180 2BEK ATP 0.0001561 0.43457 7.7821
181 2CJW GDP 0.00001741 0.5364 7.8125
182 1YZG GDP 0.00008905 0.49638 7.82123
183 3IUY AMP 0.002141 0.42328 7.89474
184 4BQS ADP 0.00001349 0.54165 7.95455
185 2GCN GDP 0.0004303 0.47099 7.9602
186 2GCO GNP 0.0002861 0.44703 7.9602
187 5L3R GCP 0.00003006 0.44652 7.97342
188 2D2F ADP 0.00007398 0.53016 8.01688
189 5HCN GCP 0.0001049 0.4931 8.01688
190 1G7S GDP 0.0001598 0.48467 8.01688
191 3FVQ ATP 0.0003312 0.42616 8.01688
192 4A4Z ANP 0.004543 0.42209 8.01688
193 1ZJ6 G3D 0.00008957 0.49626 8.02139
194 4BAS GNP 0.0003136 0.47737 8.0402
195 4H1V GNP 0.00114 0.42505 8.13008
196 3H4S ADP 0.000001443 0.62212 8.14815
197 1FWV SGA MAG FUC 0.01734 0.40796 8.20895
198 1VG8 GNP 0.0001687 0.49779 8.21256
199 1VG0 GDP 0.00009709 0.47731 8.21256
200 3W5J GDP 0.000003132 0.60345 8.33333
201 2GN3 MAN 0.02738 0.40168 8.33333
202 2W58 ADP 0.0000002495 0.66922 8.41584
203 1F9V ADP 0.000006399 0.58094 8.43882
204 1NY5 ADP 0.0000005772 0.56201 8.43882
205 1XKV ATP 0.0002505 0.47002 8.43882
206 2VQO TFG 0.004263 0.42823 8.43882
207 4OKD GLC GLC GLC 0.01526 0.40985 8.43882
208 1AQU A3P 0.009197 0.40366 8.43882
209 1KK8 BEF ADP 0.0002674 0.44862 8.44156
210 1LVG ADP 0.000005911 0.57596 8.58586
211 4GOX A3P 0.000475 0.41191 8.6262
212 3B5J 12D 0.00001332 0.55837 8.64198
213 5BXQ GDP 0.00004725 0.50907 8.66142
214 1VHT BA3 0.001113 0.44087 8.7156
215 2G77 GDP 0.0001199 0.46316 8.78049
216 1G16 GDP 0.0001403 0.43333 8.82353
217 2BCG GDP 0.00008168 0.45984 8.83002
218 2XT3 ADP 0.000002305 0.60948 8.86076
219 2WHX ADP 0.0000122 0.56708 8.86076
220 1KK1 GNP 0.00005487 0.52002 8.86076
221 2IXE ATP 0.0001272 0.43308 8.86076
222 1FQK GDP 0.0001755 0.42653 8.86076
223 2XTN GTP 0.0001409 0.42647 8.97436
224 5UQW GDP 0.0001599 0.41707 8.99471
225 4DSU GDP 0.0001796 0.40336 8.99471
226 1VG9 GDP 0.00007317 0.50031 9.18919
227 1VG1 GDP 0.00003666 0.49804 9.18919
228 5TB5 GDP 0.00009415 0.48915 9.18919
229 5TAR GDP 0.0001087 0.47494 9.18919
230 5H56 ADP 0.0001833 0.50126 9.23077
231 5H56 TYD 0.0001833 0.50126 9.23077
232 1G4U GDP 0.00006176 0.46511 9.23913
233 1MR3 G3D 0.00006748 0.487 9.39227
234 3IIJ ADP 0.00002357 0.53018 9.44444
235 3RAB GNP 0.0003241 0.48256 9.46746
236 4YMU ATP 0.00001934 0.542 9.54545
237 1O3Y GTP 0.0002136 0.42111 9.63855
238 2BME GNP 0.00006796 0.42243 9.67742
239 1S9D GDP 0.0000482 0.50867 9.7561
240 1RE0 GDP 0.00001416 0.49447 9.7561
241 2C5L GTP 0.0002019 0.40145 9.82659
242 1RYH GNP 0.0002404 0.47083 9.85222
243 5XCO GDP 0.00006225 0.48519 9.94152
244 4K81 GTP 0.0001737 0.40333 9.94152
245 3ZFD ANP 0.0001007 0.48784 9.97151
246 1UPT GTP 0.0001977 0.42976 10
247 5N69 ADP 0.0001053 0.47562 10.0503
248 1Z2A GDP 0.0003075 0.41424 10.119
249 4LPS GDP 0.00001413 0.53324 10.1266
250 1S8F GDP 0.00008524 0.4911 10.1695
251 1XTQ GDP 0.000337 0.41258 10.1695
252 1LFD GNP 0.0002308 0.40503 10.1796
253 1JJV ATP 0.00002398 0.55105 10.1942
254 5UFQ GNP 0.000132 0.41324 10.241
255 2UZI GTP 0.0001905 0.40886 10.241
256 3T12 GDP ALF 0.0001562 0.43375 10.2941
257 1Z0A GDP 0.00003162 0.51048 10.3448
258 1QHH ATP 0.00006887 0.50152 10.4348
259 1XX6 ADP 0.0001581 0.51069 10.4712
260 1G3Q ADP 0.0001186 0.49063 10.5485
261 1WQ1 GDP 0.0002311 0.41883 10.5485
262 1JI0 ATP 0.00002002 0.54954 10.8333
263 2QEN ADP 0.000003896 0.55761 10.9705
264 1YTM ATP 0.0003387 0.42857 10.9705
265 1IN4 ADP 0.0000004563 0.55164 11.0778
266 2FJU GSP 0.0004252 0.42248 11.236
267 1HE1 GDP 0.0001105 0.446 11.3636
268 1QHG ATP 0.0002573 0.46046 11.3924
269 1OW3 GDP 0.0003299 0.46967 11.399
270 3M1I GTP 0.0001939 0.40113 11.4155
271 3H86 AP5 0.00377 0.44348 11.4583
272 1FZQ GDP 0.00007444 0.50656 11.6022
273 3T5G GDP 0.0001299 0.48286 11.6022
274 1R4A GNP 0.0002291 0.41411 11.7647
275 4B47 GDP 0.00005416 0.52029 11.8143
276 2WOJ ADP ALF 0.0001522 0.4119 11.8143
277 5IRC GDP 0.002552 0.42463 11.828
278 5UWT GNP 0.0002138 0.49291 11.8881
279 5UWR GNP 0.0002084 0.40071 11.8881
280 5UWI GNP 0.0002095 0.40061 11.8881
281 5UWH GNP 0.0002117 0.40049 11.8881
282 5UWQ GNP 0.000219 0.40023 11.8881
283 5DIF GNP 0.0002203 0.40011 11.8881
284 4D0N GDP 0.00008104 0.47419 11.8919
285 5HPY GDP 0.0003385 0.44425 11.8919
286 1KMQ GNP 0.0004806 0.40689 11.9565
287 4CVN ADP 0.0000202 0.54935 12.0419
288 2A5J GDP 0.00003881 0.50647 12.0419
289 1GWN GTP 0.0006512 0.46058 12.1951
290 1DS6 GDP 0.0000852 0.47389 12.2222
291 3GJ7 GDP 0.00002098 0.53257 12.2449
292 1TU3 GNP 0.0002389 0.40378 12.2807
293 2PL3 ADP 0.0001081 0.50573 12.2881
294 3TK1 GDP 0.00004344 0.53276 12.6582
295 2IYL GDP 0.0001554 0.49145 12.6761
296 2WJG GDP 0.0000422 0.51822 12.766
297 1G7C 5GP 0.007906 0.41067 12.766
298 2W2X GSP 0.0002653 0.4329 12.9032
299 4HSE ADP 0.0000005462 0.59839 13.0802
300 2A5F GTP 0.0002452 0.41279 13.1429
301 3ZS9 ADP ALF 0.0001899 0.40922 13.1579
302 1M7G AV2 0.00002468 0.53686 13.2701
303 1R6B ADP 0.000005034 0.55392 13.5135
304 1M7B GTP 0.0004463 0.42253 13.587
305 3KTA AP5 0.0000962 0.47732 13.7363
306 2AWN ADP 0.0000003684 0.66116 13.9241
307 1FNN ADP 0.000000336 0.55999 13.9241
308 3TBK ANP 0.000847 0.46842 13.9241
309 3RLF ANP 0.0001896 0.4204 13.9241
310 4TTQ ATP 0.0003476 0.47491 13.9535
311 4M9Q GNP 0.000366 0.42043 14.0969
312 4KFU ACP 0.00002779 0.54898 14.1509
313 2J0V GDP 0.0001678 0.48369 14.1509
314 1FQJ GDP 0.00008118 0.43781 14.2857
315 5L3W GDP 0.000445 0.45879 14.346
316 5L3S GNP 0.00003249 0.44509 14.346
317 2WJH GDP 0.0001778 0.46921 14.4578
318 2WJH FLC 0.0003973 0.46101 14.4578
319 4HI0 GDP 0.00001159 0.48547 14.5729
320 3MJH GTP 0.0002291 0.40444 14.7059
321 2VB6 ADP BEF 0.0003619 0.41205 14.7651
322 2ODE ALF GDP 0.0001028 0.403 14.8936
323 1KY3 GDP 0.0001266 0.48607 15.3846
324 3KUD GDP 0.0001391 0.44152 16.0494
325 1D2N ANP 0.00001646 0.48171 16.1765
326 1M2O GNP 0.0003071 0.40942 16.3158
327 2CHG ANP 0.000006127 0.51736 16.3717
328 1EK0 GNP 0.0002571 0.40131 16.4706
329 5FG3 GDP 0.00003968 0.52685 16.8776
330 3ZQ6 ADP ALF 0.0002674 0.40401 16.9753
331 3KP6 SAL 0.01805 0.41698 17.2185
332 4U5X GNP 0.0002764 0.43869 17.4157
333 1CXZ GSP 0.0004454 0.41732 17.4419
334 2V7Q ADP 0.00005279 0.51362 17.6471
335 2V7Q ATP 0.00008137 0.49201 17.6471
336 1W0J ADP 0.00007723 0.48173 17.6471
337 1W0J ADP BEF 0.00008452 0.4626 17.6471
338 2CK3 ANP 0.0001052 0.45885 17.6471
339 2CK3 ADP 0.0001572 0.4273 17.6471
340 1B7T ADP 0.0003345 0.46437 17.9487
341 5BQ5 ADP BEF 0.000002664 0.55884 17.9894
342 3BOS CDP 0.000005784 0.55903 18.1818
343 3B7G ANP 0.0002181 0.47844 18.2609
344 2ZR9 DTP 0.00009284 0.50203 18.9112
345 5KDO GDP 0.0001089 0.44828 18.9873
346 1GOT GDP 0.0001572 0.4351 18.9873
347 1J2J GTP 0.0003056 0.41452 20
348 3GJ8 GDP 0.00004068 0.51207 20.6522
349 2A9K GDP 0.00008337 0.46901 20.6751
350 4V0K GDP 0.0004818 0.40359 20.7101
351 4QOS ADP 0.0000394 0.50618 20.7547
352 4R2I ANP 0.003292 0.439 21.4286
353 2QN6 GDP 0.00004559 0.52392 21.5054
354 4R43 GDP 0.0005516 0.46543 21.519
355 4OI4 ATP 0.0007232 0.4028 21.7391
356 1GP2 GDP 0.0001755 0.4268 22.5352
357 2RCN GDP 0.00001456 0.54007 22.7848
358 2D7C GTP 0.000225 0.40659 23.8095
359 3DZD ADP 0.0000002883 0.58775 24.1848
360 2Y65 ADP 0.000004045 0.47594 25
361 3BC1 GNP 0.0001322 0.41361 25.4237
362 2QTV GNP 0.0001596 0.41978 26.5306
363 2HCJ GDP 0.00004701 0.52328 27.027
364 3E70 GDP 0.0001651 0.48402 28.692
365 3QF7 ANP 0.0001344 0.45243 30
366 3ZIA ATP 0.00004442 0.51031 30.1587
367 3ZIA ADP 0.00004867 0.49027 30.1587
368 3GJ3 GDP 0.00002578 0.52834 30.303
369 2HV8 GTP 0.0001782 0.40981 31.25
370 2CE7 ADP 0.0000000001912 0.49831 33.4034
371 5O2T GSP 0.0001911 0.40255 34.2246
372 5UWJ GNP 0.0002095 0.40046 40
Pocket No.: 2; Query (leader) PDB : 5IFS; Ligand: ADP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 5ifs.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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