Receptor
PDB id Resolution Class Description Source Keywords
5IRC 1.72 Å EC: 3.-.-.- P190A GAP DOMAIN COMPLEX WITH RHOA RATTUS NORVEGICUS PROTEIN-PROTEIN COMPLEX TRANSITION STATE GTPASE GAP DOMAIPROTEIN BINDING
Ref.: DECIPHERING THE MOLECULAR AND FUNCTIONAL BASIS OF R FAMILY PROTEINS: A SYSTEMATIC APPROACH TOWARD SELEC INACTIVATION OF RHO FAMILY PROTEINS. J.BIOL.CHEM. V. 291 20353 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MGF D:203;
F:203;
Invalid;
Invalid;
none;
none;
submit data
81.3 F3 Mg F[Mg-...
GDP D:201;
F:201;
Valid;
Valid;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
MG D:202;
F:202;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
CL B:1501;
A:1502;
A:1501;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
35.453 Cl [Cl-]
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5IRC 1.72 Å EC: 3.-.-.- P190A GAP DOMAIN COMPLEX WITH RHOA RATTUS NORVEGICUS PROTEIN-PROTEIN COMPLEX TRANSITION STATE GTPASE GAP DOMAIPROTEIN BINDING
Ref.: DECIPHERING THE MOLECULAR AND FUNCTIONAL BASIS OF R FAMILY PROTEINS: A SYSTEMATIC APPROACH TOWARD SELEC INACTIVATION OF RHO FAMILY PROTEINS. J.BIOL.CHEM. V. 291 20353 2016
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 218 families.
1 5IRC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 176 families.
1 5IRC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 143 families.
1 5IRC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5IRC; Ligand: GDP; Similar sites found: 368
This union binding pocket(no: 1) in the query (biounit: 5irc.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4PPF FLC 0.0001234 0.51987 1.99005
2 3LRE ADP 0.00003116 0.55572 2.48756
3 3UIE ANP 0.0002123 0.47325 2.5
4 2ZR9 DTP 0.001721 0.44205 2.68817
5 5MZN ADP 0.00554 0.4277 2.68817
6 3ZS9 ADP ALF 0.0002745 0.40988 2.68817
7 3IO3 ADP 0.02678 0.40955 2.98507
8 1D2E GDP 0.0000004744 0.57663 3.22581
9 3BFV ADP 0.001044 0.45232 3.22581
10 4V03 ADP 0.001042 0.44216 3.22581
11 3FWY ADP 0.0001041 0.49252 3.48259
12 4ZNL BEF ADP 0.0009341 0.4493 3.48259
13 5M04 GDP 0.000000967 0.60514 3.76344
14 1JJV ATP 0.0002712 0.49851 3.76344
15 5G41 AP5 0.01173 0.42941 3.76344
16 4YDS ATP 0.0001734 0.50279 3.9801
17 1V8K ANP 0.0001343 0.49445 3.9801
18 2ZFI ADP 0.0002531 0.48143 3.9801
19 1T5C ADP 0.00000509 0.45307 3.9801
20 1VHT BA3 0.004658 0.41285 3.9801
21 2HCJ GDP 0.00000001807 0.68903 4.30108
22 5JBQ GDP 0.00000008619 0.64541 4.30108
23 2FH5 GTP 0.00000000541 0.61196 4.30108
24 1D8T GDP 0.0000001186 0.59455 4.30108
25 2BVN GNP 0.0000002802 0.58651 4.30108
26 5FTB ANP 0.000892 0.44519 4.30108
27 5FHD ADP ALF 0.0001642 0.44137 4.30108
28 1G3Q ADP 0.001396 0.44124 4.30108
29 3P4X ADP 0.000404 0.43839 4.30108
30 1ION ADP 0.001404 0.43632 4.30108
31 3Q9L ATP 0.00149 0.41846 4.30108
32 2GK6 ADP 0.008656 0.418 4.30108
33 1JI0 ATP 0.0004141 0.48393 4.47761
34 1YTM ATP 0.000796 0.41556 4.47761
35 4QM7 GTP 0.0007446 0.45927 4.67836
36 5BQ5 ADP BEF 0.002137 0.4281 4.7619
37 2C77 GNP 0.0000001592 0.62732 4.83871
38 1GOJ ADP 0.000005202 0.60215 4.83871
39 2C78 GNP 0.00000009759 0.55052 4.83871
40 1G6H ADP 0.00006915 0.54084 4.83871
41 4CVN ADP 0.00007402 0.52122 4.83871
42 4PFO ADP 0.0001047 0.50568 4.83871
43 3BOS CDP 0.0004438 0.46989 4.83871
44 5L3W GDP 0.0002577 0.46947 4.83871
45 3DZD ADP 0.0009158 0.4357 4.83871
46 1IN4 ADP 0.00207 0.40511 4.83871
47 3H4S ADP 0.00001632 0.56819 4.97512
48 1F9V ADP 0.0000381 0.54146 4.97512
49 5L3V GDP 0.0001263 0.48341 4.97512
50 4TTQ ATP 0.0003923 0.47243 4.97512
51 1NJF AGS 0.001416 0.44697 4.97512
52 4FRZ ADP 0.00005708 0.44687 4.97512
53 1NJF ADP 0.001167 0.44681 4.97512
54 5L3S GNP 0.000192 0.41979 4.97512
55 2WJG GDP 0.0000001994 0.62819 5.31915
56 5KUT GDP 0.00000002926 0.63312 5.37634
57 1SKQ GDP 0.0000002617 0.63269 5.37634
58 2CBZ ATP 0.000007808 0.59508 5.37634
59 1G7S GDP 0.000001251 0.5818 5.37634
60 3ZFD ANP 0.000009763 0.53345 5.37634
61 3NHB ADP 0.0002805 0.49841 5.37634
62 4NON GDP 0.0000003048 0.48276 5.37634
63 1SQ5 ADP 0.0003306 0.4701 5.37634
64 2DPY ADP 0.00131 0.45897 5.37634
65 4R2I ANP 0.003771 0.43605 5.37634
66 1IHU AF3 0.0003566 0.41896 5.37634
67 1IHU ADP 0.0003445 0.4128 5.37634
68 3FVQ ATP 0.0008826 0.41073 5.37634
69 4E03 ADP 0.000588 0.44586 5.47264
70 4MKF AP5 0.007787 0.43458 5.47264
71 4FCW ADP 0.002862 0.41686 5.47264
72 4P3Y GDP 0.00000007722 0.5896 5.49451
73 1XPJ TLA 0.01787 0.41776 5.55556
74 5I0H ADP BEF 0.00007076 0.50509 5.91398
75 5X40 ACP 0.002419 0.43797 5.91398
76 1FNN ADP 0.001413 0.41201 5.91398
77 5N69 ADP 0.00003038 0.49809 5.97015
78 4ZKD GDP 0.0000004264 0.49113 5.97015
79 3EZ2 ADP 0.001316 0.45304 5.97015
80 2XAU ADP 0.001653 0.43313 5.97015
81 2OG2 MLI 0.003853 0.43303 5.97015
82 3B9Q MLI 0.006785 0.42175 5.97015
83 2WJH GDP 0.0000006192 0.57683 6.0241
84 2WJH FLC 0.00008233 0.49178 6.0241
85 4H1V GNP 0.000007769 0.51379 6.45161
86 2Y65 ADP 0.00001595 0.45271 6.45161
87 3COB ADP 0.00002598 0.44872 6.45161
88 4QOS ADP 0.001917 0.43023 6.45161
89 4LJ9 ACP 0.007223 0.41254 6.45161
90 4PJ3 ANP 0.004852 0.40465 6.45161
91 1B7T ADP 0.00007506 0.49358 6.46766
92 1KK8 BEF ADP 0.0000528 0.47679 6.46766
93 4R43 GDP 0.0003552 0.47447 6.46766
94 4PX9 ADP 0.00048 0.4743 6.46766
95 2CHG ANP 0.001358 0.42019 6.46766
96 2FNA ADP 0.001311 0.40007 6.46766
97 4BQS ADP 0.000558 0.46519 6.81818
98 4PC3 GDP 0.0000008775 0.56629 6.96517
99 3E70 GDP 0.0003824 0.46719 6.96517
100 2WHX ADP 0.00007643 0.5277 6.98925
101 2OFW ADX 0.00179 0.46408 6.98925
102 2JLR ANP 0.0004489 0.44858 6.98925
103 4JLV ADP 0.003634 0.4316 6.98925
104 4D81 ADP 0.001273 0.42924 6.98925
105 1XKV ATP 0.004192 0.41491 6.98925
106 4A4Z ANP 0.006458 0.41484 6.98925
107 1LVG ADP 0.0001656 0.50378 7.07071
108 5MVR ADP 0.0002274 0.48363 7.40741
109 1YRB GDP 0.0000001009 0.60628 7.46269
110 4R98 GNH 0.000003099 0.57185 7.46269
111 2XT3 ADP 0.00002084 0.56127 7.46269
112 5VGR GDP 0.002306 0.41044 7.46269
113 3U6B GDP 0.00000003389 0.67578 7.52688
114 3U6K GDP 0.00000006627 0.65081 7.52688
115 4G5G GDP 0.00000009372 0.6437 7.52688
116 4LYA ATP 0.0001433 0.48685 7.52688
117 3T34 GDP 0.00001107 0.47484 7.52688
118 2FAH GDP 0.0002721 0.45845 7.52688
119 4XVU ATP 0.0002354 0.41909 7.52688
120 5L3R GCP 0.000255 0.41589 7.52688
121 2RHO GSP 0.01462 0.40445 7.52688
122 1U0J ADP 0.003449 0.40046 7.52688
123 2BEK ATP 0.0008051 0.40909 7.9602
124 5M7P ADP 0.001588 0.40857 7.9602
125 4DCT GDP 0.00000002388 0.66107 8.06452
126 3CNL GNP 0.0000007039 0.61184 8.06452
127 2W58 ADP 0.00002664 0.56126 8.45771
128 3DKP ADP 0.002598 0.43358 8.45771
129 4IEE AGS 0.005597 0.42247 8.45771
130 4QRH 0O2 0.007609 0.41123 8.45771
131 5GJC ATP 0.0003381 0.47549 8.60215
132 1OXV ANP 0.0005386 0.42771 8.60215
133 1WDT GTP 0.0000294 0.48276 8.95522
134 4YMU ATP 0.0008351 0.46262 8.95522
135 2FSH ANP 0.005043 0.42467 8.95522
136 4LPS GDP 0.0000001192 0.62888 9.13978
137 1M7G ADX 0.001109 0.46524 9.13978
138 2PL3 ADP 0.0007873 0.46387 9.13978
139 1M7G AV2 0.00008369 0.46234 9.13978
140 1M7G ADP 0.001165 0.46123 9.13978
141 1FP6 ADP 0.0003401 0.45326 9.13978
142 4WEI GLC GAL 0.01205 0.41879 9.13978
143 4U00 ADP 0.0001084 0.41216 9.13978
144 3PQC GDP 0.00000004129 0.64029 9.23077
145 5IRR GSP 0.0000004997 0.52707 9.45274
146 3EWA ANP 0.0006952 0.46067 9.45274
147 4YS0 ADP 0.002109 0.4138 9.45274
148 4RD0 GDP 0.00000001504 0.57824 9.67742
149 5I34 GDP 0.001168 0.44482 9.67742
150 1Z6T ADP 0.0005316 0.43507 9.67742
151 2VF7 ADP 0.001997 0.43407 9.67742
152 3B5J 12D 0.0003262 0.48909 10.2151
153 5TSH ADP 0.0008184 0.47299 10.2151
154 5TSH ANP 0.0005067 0.46717 10.2151
155 5GVR LMR 0.000871 0.46373 10.2151
156 3B7G ANP 0.001915 0.43491 10.2151
157 1NY5 ADP 0.001123 0.42249 10.2151
158 5J1J ANP 0.0004555 0.40864 10.2151
159 2ZPA ADP 0.002734 0.40069 10.4478
160 1XX6 ADP 0.0005297 0.48477 10.4712
161 3DC4 ADP 0.0003131 0.48999 10.7527
162 2ZE7 DST 0.01081 0.41215 10.7527
163 4XTR ADP 0.0001738 0.44715 10.8108
164 4XTR ATP 0.0002083 0.42087 10.8108
165 2HF9 GSP 0.000002069 0.47663 10.9453
166 3WY9 GDP 0.0000000622 0.66298 11.2903
167 3WYA GDP 0.00000009193 0.64409 11.2903
168 2PZE ATP 0.00006297 0.5396 11.2903
169 1R0X ATP 0.0008545 0.42193 11.2903
170 1OYY AGS 0.009814 0.40622 11.2903
171 5XDR ADP 0.001611 0.43838 11.4428
172 1TQ4 GDP 0.0000006631 0.53406 11.828
173 2Q2Y MKR 0.004935 0.44233 11.828
174 2Q2Y ADP 0.005282 0.44193 11.828
175 5IFS ADP 0.002552 0.42463 11.828
176 2QZ4 ADP 0.001133 0.44052 11.9403
177 4ZG4 VO4 ADP 0.00006609 0.43574 11.9403
178 1OE0 TTP 0.003814 0.43364 11.9403
179 1JJ7 ADP 0.00004228 0.55452 12.3656
180 1G7C 5GP 0.00001469 0.5399 12.3656
181 3TBK ANP 0.001399 0.45755 12.3656
182 5HR5 ADP 0.001156 0.42257 12.3656
183 2WIC GNP 0.000002642 0.56682 12.4378
184 1H65 GDP 0.000006677 0.48349 12.4378
185 1W0J ADP 0.0002291 0.46101 12.4378
186 1W0J ADP BEF 0.0007952 0.42107 12.4378
187 4RZ3 ADP 0.003937 0.40328 12.4378
188 4WOP CTP 0.001758 0.4231 12.4444
189 2ZPT A3P 0.03711 0.41003 12.9032
190 2VVG ADP 0.000006181 0.59621 12.9353
191 2WZF BGC 0.01331 0.41001 12.9353
192 3TK1 GDP 0.0000003029 0.64031 13.4328
193 3IIJ ADP 0.0002957 0.47824 13.8889
194 1UKZ ADP 0.01307 0.41596 13.9303
195 2AWN ADP 0.00001529 0.58143 13.9785
196 4WZ6 ATP 0.0001311 0.51595 13.9785
197 1AQU A3P 0.0109 0.40028 13.9785
198 2KIN ADP 0.000004037 0.45884 14
199 5H56 TYD 0.003092 0.4424 14.359
200 5H56 ADP 0.003092 0.4424 14.359
201 5FG3 GDP 0.00000003481 0.60411 14.5161
202 1DAR GDP 0.000001691 0.58429 14.5161
203 5GOE GDP 0.000001309 0.57272 14.5161
204 3WXM GTP 0.0000001792 0.63607 14.9254
205 3VMF GTP 0.0000001548 0.51234 14.9254
206 2IS6 ADP 0.0008889 0.45563 14.9254
207 5CK5 GDP 0.00000036 0.62597 15.5914
208 3DEF GDP 0.00001052 0.51966 15.5914
209 3KTA AP5 0.002099 0.41916 15.6069
210 2XTZ GSP 0.0000001588 0.52127 16.129
211 1ZCB GDP 0.000001689 0.59015 16.6667
212 3AB3 GDP 0.000001249 0.58602 16.6667
213 1KK1 GNP 0.0000001805 0.57524 16.6667
214 4BAS GNP 0.000005281 0.5597 16.6667
215 1Y3A GDP 0.000004341 0.49038 16.6667
216 2OM2 GDP 0.00001356 0.48769 16.6667
217 3CX8 GSP 0.0000008101 0.4772 16.6667
218 1BH2 GSP 0.000001091 0.47353 16.6667
219 2ODE ALF GDP 0.000001158 0.47352 16.6667
220 1SVK ALF GDP 0.000001219 0.46593 16.6667
221 1BG2 ADP 0.000004193 0.45503 16.9154
222 1MKY GDP 0.00000002356 0.67205 17.2043
223 2VB6 ADP BEF 0.00008546 0.43318 17.4497
224 4J0Q GDP 0.0000000746 0.65915 17.7419
225 2V7Q ATP 0.0001884 0.47559 17.8082
226 2V7Q ADP 0.0003506 0.47473 17.8082
227 2CK3 ANP 0.0007387 0.42269 17.8082
228 2CK3 ADP 0.0007792 0.40098 17.8082
229 2QN6 GDP 0.0000000264 0.68105 18.2796
230 3W5J GDP 0.00002247 0.55868 18.8172
231 1HTW ADP 0.0001526 0.47117 18.9873
232 3ZIA ATP 0.0001629 0.47009 19.0476
233 3ZIA ADP 0.0002965 0.46932 19.0476
234 2IYL GDP 0.0003352 0.47566 19.3662
235 3A1S GDP 0.0000003438 0.60767 19.403
236 1NRJ GTP 0.0000007726 0.53673 20.2532
237 1CS4 GSP 0.0000008499 0.48538 20.4301
238 1AZT GSP 0.0000005254 0.48314 20.4301
239 4IDN GNP 0.0003163 0.42151 20.4301
240 3A4M ADP 0.00009677 0.51542 20.9677
241 2X77 GDP 0.00000009092 0.6343 21.6931
242 1YZG GDP 0.000001196 0.58269 21.7877
243 5LTJ ADP 0.0003639 0.46818 21.8905
244 5LTJ BEF 0.004694 0.44496 21.8905
245 1ZJ6 G3D 0.0000008298 0.59002 22.043
246 1PUJ GNP 0.0000004766 0.57655 22.3881
247 2A5F GTP 0.0000005084 0.51293 22.8571
248 5KDO GDP 0.00001136 0.49115 22.973
249 5IRN ADP 0.0004177 0.44953 23.1183
250 5EE5 GTP 0.00000006138 0.56344 23.9766
251 3PCR GTP 0.0000009007 0.51477 24.0741
252 4M9Q GNP 0.0000002866 0.54082 24.2291
253 1MR3 G3D 0.000002763 0.54872 24.3094
254 2OBM ADP 0.001972 0.45418 24.3781
255 3N5C GDP 0.000000998 0.59512 24.6914
256 4NCN GTP 0.00000001763 0.565 24.7312
257 4TMZ GSP 0.00000001909 0.56459 24.7312
258 2D7D ADP 0.002398 0.41492 25
259 1Y63 ADP 0.0006165 0.46314 25.5435
260 5LB3 ADP 0.0001738 0.49571 27.3632
261 5KSP GDP 0.000000008963 0.6807 27.4194
262 2RCN GDP 0.00000001716 0.67856 27.957
263 5KSZ GCP 0.0000000364 0.64275 27.957
264 1F6B GDP 0.000008344 0.54379 27.957
265 3DOE GTP 0.0000002107 0.53306 27.957
266 1UPT GTP 0.0000002049 0.54344 28.3333
267 5HCN GCP 0.0000001886 0.61969 29.5699
268 4KAX GTP 0.0000002308 0.54369 30.1775
269 4HI0 GDP 0.00001011 0.49299 30.3483
270 5DI3 GNP 0.0000002857 0.5412 31.3514
271 1R4A GNP 0.0000001284 0.53121 31.3725
272 1KSH GDP 0.00000003267 0.65907 31.7204
273 2W83 GTP 0.0000002202 0.53174 32.1212
274 3AQ4 GDP 0.000001554 0.57746 32.6087
275 1FQJ ALF 0.0001071 0.51939 32.7957
276 1FQJ GDP 0.0000009768 0.51467 32.7957
277 3T1O GDP 0.000002145 0.56308 33.3333
278 3T12 GDP ALF 0.0000005928 0.52913 33.3333
279 4HSE ADP 0.0002144 0.47878 33.3333
280 4YLG GDP 0.000000735 0.55599 34.104
281 2ZEJ GDP 0.000008043 0.45094 34.7826
282 1ZD9 GDP 0.0000001037 0.5774 34.9462
283 4V0K GDP 0.00000383 0.47597 35.503
284 1J2J GTP 0.00000002543 0.56376 36.1446
285 2J59 GTP 0.0000001358 0.54099 36.1446
286 1O3Y GTP 0.0000002234 0.53069 36.1446
287 3GJX GTP 0.000000001423 0.738 36.5591
288 3GJ4 GDP 0.00000004466 0.65892 36.5591
289 3GJ7 GDP 0.00000005289 0.65544 36.5591
290 3GJ8 GDP 0.0000001089 0.63068 36.5591
291 3GJ5 GDP 0.0000001152 0.62956 36.5591
292 5UWT GNP 0.000000001138 0.7426 37.0968
293 4HAT GNP 0.000000001467 0.74023 37.0968
294 3GJ3 GDP 0.00000007587 0.64803 37.0968
295 5DIF GNP 0.0000000009102 0.57535 37.0968
296 5UWU GNP 0.0000000009562 0.57462 37.0968
297 5UWJ GNP 0.0000000009911 0.57449 37.0968
298 5UWI GNP 0.000000001026 0.57402 37.0968
299 5UWO GNP 0.000000001001 0.57397 37.0968
300 5UWQ GNP 0.000000001059 0.57368 37.0968
301 5UWR GNP 0.000000001168 0.5724 37.0968
302 5DHF GNP 0.0000000012 0.57224 37.0968
303 5UWW GNP 0.000000001277 0.57136 37.0968
304 5UWH GNP 0.000000001349 0.57074 37.0968
305 5DI9 GNP 0.00000000113 0.56197 37.0968
306 5UWP GNP 0.00000000127 0.56069 37.0968
307 5UWS GNP 0.000000001736 0.55727 37.0968
308 1M2O GNP 0.0000003699 0.50405 37.0968
309 1S9D GDP 0.000003055 0.56392 37.1951
310 1RE0 GDP 0.0000006012 0.55722 37.1951
311 4B47 GDP 0.0000001086 0.65124 37.6344
312 3M1I GTP 0.000000001775 0.56766 37.6344
313 3WYF GTP 0.00000000458 0.54712 37.6344
314 3WYG GTP 0.000000007896 0.54147 38.4615
315 1Z06 GNP 0.000000003362 0.58018 38.7097
316 1WA5 GTP 0.000000002231 0.5261 39.2045
317 2QTV GNP 0.000002237 0.49104 41.3174
318 3BC1 GNP 0.000000005838 0.70614 41.3979
319 2CJW GDP 0.00000001228 0.68542 41.3979
320 3CPJ GDP 0.00000004768 0.64125 41.3979
321 3Q72 GNP 0.000000002377 0.64854 42.1687
322 2BME GNP 0.000000001922 0.72888 43.5484
323 1FZQ GDP 0.0000006161 0.60502 43.6464
324 3RWO GDP 0.00000002904 0.67331 43.7838
325 1YZN GNP 0.000000001071 0.57064 43.7838
326 3E5H GNP 0.000000005672 0.5627 43.8202
327 4GOJ GNP 0.0000001948 0.54485 43.9153
328 2BCG GDP 0.00000002796 0.59685 44.086
329 1OIX GDP 0.000000001586 0.5767 44.086
330 2HT6 GDP 0.00000001573 0.69196 44.2529
331 2A5J GDP 0.000000008428 0.67135 44.6237
332 1OIV GDP 0.00000003354 0.67036 44.6237
333 4ZI2 GNP 0.0000001629 0.54722 44.7368
334 1X1R GDP 0.000000007859 0.54342 44.9438
335 5SZH GNP 0.000000001191 0.74166 45.1613
336 3TKL GTP 0.0000000005857 0.60071 45.1613
337 2F9L GDP 0.0000000265 0.55669 45.1613
338 1Z0F GDP 0.00000001188 0.67505 45.2514
339 1Z0K GTP 0.000000003686 0.58929 45.3488
340 3Q85 GNP 0.00000002826 0.62124 45.5621
341 4D0G GTP 0.000000007041 0.59254 45.7143
342 5JCZ GDP 0.000000004529 0.62738 46.3687
343 5UQW GDP 0.0000000344 0.54419 46.5608
344 4LX0 BEF GDP 0.000000001256 0.74058 46.8927
345 3SFV GDP 0.00000001683 0.67237 46.9613
346 2A9K GDP 0.000000003467 0.64923 47.0588
347 1EK0 GNP 0.000000004588 0.56042 47.0588
348 1VG8 GNP 0.000000003675 0.71849 47.3118
349 1VG0 GDP 0.00000002814 0.62957 47.3118
350 4DSU GDP 0.00000001768 0.53454 47.3118
351 3NKV GNP 0.000000000213 0.60257 47.4286
352 3T5G GDP 0.0000000498 0.63663 47.5138
353 1VG9 GDP 0.0000000186 0.66608 47.5676
354 1VG1 GDP 0.00000002034 0.6409 47.5676
355 4DKX GDP 0.000000002923 0.71491 47.8495
356 1TU3 GNP 0.000000002231 0.72583 47.9532
357 4C4P GNP 0.000000004451 0.5513 47.9769
358 5TB5 GDP 0.000000005373 0.68015 48.1081
359 5TAR GDP 0.000000008985 0.65055 48.1081
360 1D5C GDP 0.000000005114 0.64333 48.1481
361 3MJH GTP 0.0000000002622 0.59816 48.2143
362 1R2Q GNP 0.000000001185 0.50293 48.2353
363 1KY3 GDP 0.0000001465 0.61916 48.3517
364 1ZC3 GNP 0.0000000004998 0.75951 48.5714
365 1XTQ GDP 0.0000002013 0.53024 48.5876
366 1UAD GNP 0.0000000001337 0.78344 49.1429
367 1KAO GDP 0.0000000441 0.60657 49.7006
368 1YVD GNP 0.000000001066 0.5806 49.7041
Pocket No.: 2; Query (leader) PDB : 5IRC; Ligand: GDP; Similar sites found: 3
This union binding pocket(no: 2) in the query (biounit: 5irc.bio2) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3KJI ADP 0.02985 0.40351 5.47264
2 2ZE7 AMP 0.01028 0.41171 10.7527
3 4U60 SIA GAL NGA 0.02386 0.40198 18.2796
Pocket No.: 3; Query (leader) PDB : 5IRC; Ligand: GDP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 5irc.bio3) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 5IRC; Ligand: GDP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 5irc.bio3) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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